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272-24-2,MFCD11110440
Catalog No.:AA007LKK

272-24-2 | Thieno[2,3-d]pyrimidine

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250mg
98%
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$53.00   $37.00
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1g
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$209.00   $146.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA007LKK
Chemical Name:
Thieno[2,3-d]pyrimidine
CAS Number:
272-24-2
Molecular Formula:
C6H4N2S
Molecular Weight:
136.1744
MDL Number:
MFCD11110440
SMILES:
c1ncc2c(n1)scc2
Properties
Computed Properties
 
Complexity:
107  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
XLogP3:
1.6  

Literature

Title: Novel thieno[2,3-d]pyrimidines: their design, synthesis, crystal structure analysis and pharmacological evaluation.

Journal: Organic & biomolecular chemistry 20120807

Title: Discovery of novel c-Met kinase inhibitors bearing a thieno[2,3-d]pyrimidine or furo[2,3-d]pyrimidine scaffold.

Journal: Bioorganic & medicinal chemistry 20110701

Title: Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity.

Journal: Chemistry Central journal 20110101

Title: Discovery of novel Thieno[2,3-d]pyrimidin-4-yl hydrazone-based cyclin-dependent kinase 4 inhibitors: synthesis, biological evaluation and structure-activity relationships.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Synthesis and screening of some novel fused thiophene and thienopyrimidine derivatives for anti-avian influenza virus (H5N1) activity.

Journal: European journal of medicinal chemistry 20101101

Title: Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of cyclin D1-CDK4: synthesis, biological evaluation and structure-activity relationships. Part 2.

Journal: Bioorganic & medicinal chemistry 20091201

Title: Analogs of a 4-aminothieno[2,3-d]pyrimidine lead (QB13) as modulators of P-glycoprotein substrate specificity.

Journal: Bioorganic & medicinal chemistry letters 20091101

Title: Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents.

Journal: Journal of medicinal chemistry 20090813

Title: Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: synthesis, biological evaluation, and structure-activity relationships.

Journal: Bioorganic & medicinal chemistry letters 20090115

Title: Synthesis and receptor binding of new thieno[2,3-d]-pyrimidines as selective ligands of 5-HT(3) receptors.

Journal: Archiv der Pharmazie 20080601

Title: Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20071201

Title: Synthesis and antimicrobial activity of some cyclic and acyclic nucleosides of thieno[2,3-d]pyrimidines.

Journal: Nucleosides, nucleotides & nucleic acids 20070101

Title: Synthesis of thieno[2,3-d]pyrimidin-2-ylmethanamine combinatorial library with four diversity points.

Journal: Journal of combinatorial chemistry 20070101

Title: Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns.

Journal: Journal of medicinal chemistry 20060629

Title: Synthesis and antiviral screening of some thieno[2,3-d]pyrimidine nucleosides.

Journal: Nucleosides, nucleotides & nucleic acids 20060101

Title: Synthesis of certain new thiieno [2,3-d] pyrimidines as potential antitumor and radioprotective agents.

Journal: Arzneimittel-Forschung 20060101

Title: Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines.

Journal: European journal of medicinal chemistry 20030601

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