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27210-57-7,MFCD00238644
Catalog No.:AA0037N0

27210-57-7 | Miltirone

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$79.00   $55.00
- +
5mg
≥95%
in stock  
$368.00   $257.00
- +
10mg
≥95%
in stock  
$655.00   $458.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0037N0
Chemical Name:
Miltirone
CAS Number:
27210-57-7
Molecular Formula:
C19H22O2
Molecular Weight:
282.3768
MDL Number:
MFCD00238644
SMILES:
CC(C1=Cc2ccc3c(c2C(=O)C1=O)CCCC3(C)C)C
NSC Number:
639662
Properties
Properties
 
Form:
Solid  
MP:
100 - 105°C  

Computed Properties
 
Complexity:
498  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
4.9  

Literature

Title: Effects of tanshinones from Salvia miltiorrhiza on CYP2C19 activity in human liver microsomes: enzyme kinetic and molecular docking studies.

Journal: Chemico-biological interactions 20150325

Title: Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases.

Journal: Bioorganic & medicinal chemistry 20121001

Title: In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica.

Journal: Bioorganic & medicinal chemistry 20110815

Title: [Chemical constituents from Salvia przewalskii Maxim].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110701

Title: Cytotoxic activity of proflavine diureas: synthesis, antitumor, evaluation and DNA binding properties of 1',1''-(acridin-3,6-diyl)-3',3''-dialkyldiureas.

Journal: Bioorganic & medicinal chemistry 20080401

Title: Identification of miltirone as active ingredient of Salvia miltiorrhiza responsible for the reducing effect of root extracts on alcohol intake in rats.

Journal: Alcoholism, clinical and experimental research 20060501

Title: Synthesis of miltirone analogues as inhibitors of Cdc25 phosphatases.

Journal: Bioorganic & medicinal chemistry letters 20060401

Title: Inhibition by miltirone of up-regulation of GABAA receptor alpha4 subunit mRNA by ethanol withdrawal in hippocampal neurons.

Journal: European journal of pharmacology 20040628

Title: C M Lee, et al. Miltirone, a central benzodiazepine receptor partial agonist from a Chinese medicinal herb Salvia miltiorrhiza. Neurosci Lett. 1991 Jun 24;127(2):237-41.

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