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[1]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2011/17108,2011,A2
[2]Zhang,Hao;Liu,Jun;Zhang,Luyong;Kong,Lingyi;Yao,Hequan;Sun,Hongbin[BioorganicandMedicinalChemistryLetters,2012,vol.22,#11,p.3598-3602]
[3]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2012/85665,2012,A2
[4]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2012/85665,2012,A2
[5]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2012/85665,2012,A2
[6]CurrentPatentAssignee:SINOBIOPHARMACEUTICALLIMITED-CN104610237,2018,B
[1]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2011/17108,2011,A2
[2]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2012/85665,2012,A2
[3]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2012/85665,2012,A2
[4]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2012/85665,2012,A2
[5]CurrentPatentAssignee:SUNPHARMACEUTICALINDUSTRIESLIMITED-WO2016/38520,2016,A1
[6]CurrentPatentAssignee:HAOCONGMEI-CN104230818,2018,B
[1]Patent:WO2011/17108,2011,A2
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[1]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-WO2011/17108,2011,A2
[2]Zhang,Hao;Liu,Jun;Zhang,Luyong;Kong,Lingyi;Yao,Hequan;Sun,Hongbin[BioorganicandMedicinalChemistryLetters,2012,vol.22,#11,p.3598-3602]
[3]CurrentPatentAssignee:MEGAFINEPHARMA(P)LTD.-WO2014/102830,2014,A1
[4]CurrentPatentAssignee:DRREDDY'SLABORATORIESLIMITED-US2015/73146,2015,A1
[5]CurrentPatentAssignee:CIPLALTD;COTTRILLEMILY-WO2016/30704,2016,A1
[6]CurrentPatentAssignee:CIPLALTD;COTTRILLEMILY-WO2016/30704,2016,A1
[7]CurrentPatentAssignee:CHENGDUHUAYUPHARMACEUTICAL-CN105669681,2016,A
[8]CurrentPatentAssignee:HAISCOPHARMACEUTICALGROUPCO.,LTD.-CN103664958,2017,B
[9]CurrentPatentAssignee:SHANGHAIHUAYUANMEDICINETECHDEV-CN106866682,2017,A
[10]CurrentPatentAssignee:HUIZHOUXINLITAIPHARMACEUTICAL;SHENZHENSALUBRISPHARMACEUTICALSCO.,LTD.-CN105153167,2017,B
[11]CurrentPatentAssignee:HUNANTIANJICOTTAGEPHARMACEUTICAL-CN107337675,2017,A
[12]CurrentPatentAssignee:JINGCHUUNIVERSITYOFTECHNOLOGY-CN107089984,2017,A
[13]CurrentPatentAssignee:TIANJINCHASESUNPHARMACEUTICALCOLTD-CN106543191,2017,A
[14]CurrentPatentAssignee:BEIJINGDONGXULIPHARMACEUTICALTECH-CN108329320,2018,A
[15]CurrentPatentAssignee:HEBEIKIVIPHARM-CN108276417,2018,A
[16]CurrentPatentAssignee:JIANGXIGUOYAOPHARMACEUTICAL-CN108892670,2018,A
[17]CurrentPatentAssignee:YUTIANRONG;YuTianrong-CN108299441,2018,A
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[19]CurrentPatentAssignee:NANJINGYIXINHEPHARMATECH-CN111978326,2020,A
[20]CurrentPatentAssignee:ZAKLADYFARMACEUTYCZNEPOLPHARMAS.A.-WO2021/245220,2021,A1
Title: Critical Role of P2Y(12) Receptor in Regulation of Th17 Differentiation and Experimental Autoimmune Encephalomyelitis Pathogenesis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20170701
Title: A semi-quantitative translational pharmacology analysis to understand the relationship between in vitro ENT1 inhibition and the clinical incidence of dyspnoea and bronchospasm.
Journal: Toxicology and applied pharmacology 20170215
Title: Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor.
Journal: Journal of thrombosis and haemostasis : JTH 20141101
Title: Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1.
Journal: Journal of cardiovascular pharmacology and therapeutics 20140301
Title: Lead optimization of ethyl 6-aminonicotinate acyl sulfonamides as antagonists of the P2Y12 receptor. separation of the antithrombotic effect and bleeding for candidate drug AZD1283.
Journal: Journal of medicinal chemistry 20130912
Title: Lack of clinically significant pharmacological interactions between ticagrelor and enoxaparin or unfractionated heparin in healthy subjects.
Journal: Journal of clinical pharmacy and therapeutics 20121201
Title: The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day.
Journal: Drugs 20121112
Title: Safety profile and bleeding risk of ticagrelor compared with clopidogrel.
Journal: Expert opinion on drug safety 20121101
Title: [Platelet inhibitors in clinical practice].
Journal: Therapeutische Umschau. Revue therapeutique 20121101
Title: Identification of high-affinity P2Y₁₂ antagonists based on a phenylpyrazole glutamic acid piperazine backbone.
Journal: Journal of medicinal chemistry 20121025
Title: Factors contributing to the lower mortality with ticagrelor compared with clopidogrel in patients undergoing coronary artery bypass surgery.
Journal: Journal of the American College of Cardiology 20121023
Title: Antiplatelet therapy for patients with diabetes mellitus and acute coronary syndrome.
Journal: Primary care diabetes 20121001
Title: Current antiplatelet options for NSTE-ACS patients.
Journal: QJM : monthly journal of the Association of Physicians 20121001
Title: Improving long-term ACS management: is there a role for the new antiplatelets?
Journal: Journal of interventional cardiology 20121001
Title: Acute ST-elevation myocardial infarction.
Journal: Current opinion in critical care 20121001
Title: Evaluation of ticagrelor pharmacodynamic interactions with reversibly binding or non-reversibly binding P2Y(12) antagonists in an ex-vivo canine model.
Journal: Thrombosis research 20121001
Title: Review of ticagrelor in the management of acute coronary syndromes.
Journal: Expert opinion on drug metabolism & toxicology 20121001
Title: New anti-platelet agents: the end of resistance?
Journal: Thrombosis research 20121001
Title: Ticagrelor (brilinta), an antiplatelet drug for acute coronary syndrome.
Journal: P & T : a peer-reviewed journal for formulary management 20121001
Title: Letter by Fort and Plachetka regarding article, 'association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from PLATO'.
Journal: Circulation 20120911
Title: Pharmacokinetics, pharmacodynamics, and safety of ticagrelor in volunteers with severe renal impairment.
Journal: Journal of clinical pharmacology 20120901
Title: Platelets in atherothrombosis--diagnostic and prognostic value of platelet activation in patients with atherosclerotic diseases.
Journal: Current vascular pharmacology 20120901
Title: Platelet hyperreactivity and stent thrombosis in patients undergoing coronary stenting.
Journal: Current vascular pharmacology 20120901
Title: P2Y(12) receptors in platelets and other hematopoietic and non-hematopoietic cells.
Journal: Purinergic signalling 20120901
Title: Novel antiplatelet therapy in acute coronary syndromes: what is new in the pipeline?
Journal: Current vascular pharmacology 20120901
Title: Antiplatelet therapy: Treatment with ticagrelor for 12 months after ACS is cost-effective.
Journal: Nature reviews. Cardiology 20120901
Title: Updating an institutional chest pain algorithm: incorporating new evidence on emerging pharmacotherapy.
Journal: Critical pathways in cardiology 20120901
Title: Viewpoint: Central adjudication of myocardial infarction in outcome-driven clinical trials--common patterns in TRITON, RECORD, and PLATO?
Journal: Thrombosis and haemostasis 20120901
Title: UA/NSTEMI: Are you following the latest guidelines?
Journal: Nursing 20120901
Title: Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes-insights from the PLATelet inhibition and patient Outcomes (PLATO) trial.
Journal: American heart journal 20120901
Title: Ticagrelor: molecular discovery to clinical evidence: ticagrelor: a novel antiplatelet agent.
Journal: Indian heart journal 20120901
Title: [Medication of the month. Ticagrelor (Brilique): potent oral antagonist of platelet activity].
Journal: Revue medicale de Liege 20120901
Title: Novel platelet ADP P2Y12 inhibitors in the treatment of acute coronary syndrome.
Journal: Cardiovascular therapeutics 20120801
Title: Lack of significant food effect on the pharmacokinetics of ticagrelor in healthy volunteers.
Journal: Journal of clinical pharmacy and therapeutics 20120801
Title: Effect of age and gender on pharmacokinetics and pharmacodynamics of a single ticagrelor dose in healthy individuals.
Journal: European journal of clinical pharmacology 20120801
Title: Which antiplatelet agent for whom? Which patient populations benefit most from novel antiplatelet agents (ticagrelor, prasugrel)?
Journal: Current cardiology reports 20120801
Title: Platelet function and inhibition in ischemic heart disease.
Journal: Current cardiology reports 20120801
Title: Network meta-analysis of prasugrel, ticagrelor, high- and standard-dose clopidogrel in patients scheduled for percutaneous coronary interventions.
Journal: Thrombosis and haemostasis 20120801
Title: Ticagrelor in clopidogrel-resistant patients undergoing maintenance hemodialysis.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20120801
Title: Clinical pharmacogenomics of warfarin and clopidogrel.
Journal: Journal of pharmacy practice 20120801
Title: Ticagrelor versus prasugrel in acute coronary syndrome patients with high on-clopidogrel platelet reactivity following percutaneous coronary intervention: a pharmacodynamic study.
Journal: Journal of the American College of Cardiology 20120717
Title: Quantitative comparison of clopidogrel 600 mg, prasugrel and ticagrelor, against clopidogrel 300 mg on major adverse cardiovascular events and bleeding in coronary stenting: synthesis of CURRENT-OASIS-7, TRITON-TIMI-38 and PLATO.
Journal: International journal of cardiology 20120712
Title: Baseline Q waves as a prognostic modulator in patients with ST-segment elevation: insights from the PLATO trial.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20120710
Title: Ticagrelor, but not clopidogrel and prasugrel, prevents ADP-induced vascular smooth muscle cell contraction: a placebo-controlled study in rats.
Journal: Thrombosis research 20120701
Title: Prasugrel during primary percutaneous coronary intervention: evidence from clinical data.
Journal: Current vascular pharmacology 20120701
Title: Ticagrelor in ST-elevation myocardial infarction.
Journal: Current vascular pharmacology 20120701
Title: Advances in antiplatelet therapy for acute coronary syndromes.
Journal: Postgraduate medical journal 20120701
Title: Lessons from platelet inhibition and patient outcomes.
Journal: Current opinion in cardiology 20120701
Title: Comparative pharmacokinetics and pharmacodynamics of platelet adenosine diphosphate receptor antagonists and their clinical implications.
Journal: Clinical pharmacokinetics 20120701
Title: Farnesyl pyrophosphate is an endogenous antagonist to ADP-stimulated P2Y₁₂ receptor-mediated platelet aggregation.
Journal: Thrombosis and haemostasis 20120701
Title: New drugs 2012, part 2.
Journal: Nursing 20120701
Title: Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies.
Journal: American heart journal 20120701
Title: Atopaxar: a review of its mechanism of action and role in patients with coronary artery disease.
Journal: Future cardiology 20120701
Title: Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack.
Journal: Circulation 20120612
Title: Beware of novel antiplatelet therapy in acute coronary syndrome patients with previous stroke.
Journal: Circulation 20120612
Title: Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model.
Journal: Journal of cardiovascular pharmacology and therapeutics 20120601
Title: Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies.
Journal: Clinical pharmacokinetics 20120601
Title: Ticagrelor: oral reversible P2Y(12) receptor antagonist for the management of acute coronary syndromes.
Journal: Clinical therapeutics 20120601
Title: Synthesis and biological evaluation of ticagrelor derivatives as novel antiplatelet agents.
Journal: Bioorganic & medicinal chemistry letters 20120601
Title: Management of non-ST-segment elevation acute coronary syndrome: comparison of the updated guidelines from North America and Europe.
Journal: Critical pathways in cardiology 20120601
Title: Use of cilostazol in percutaneous coronary interventions.
Journal: The Annals of pharmacotherapy 20120601
Title: Meeting new challenges with antiplatelet therapy in primary care.
Journal: The Journal of family practice 20120601
Title: [Platelet function: new drugs, new assays : possible impacts on operative medicine?].
Journal: Der Anaesthesist 20120601
Title: Unstable angina and non-ST elevation myocardial infarction.
Journal: American journal of respiratory and critical care medicine 20120501
Title: Pharmacokinetic, pharmacodynamic and pharmacogenetic profile of the oral antiplatelet agent ticagrelor.
Journal: Clinical pharmacokinetics 20120501
Title: Personalised antiplatelet therapy in stent thrombosis: observations from the Clopidogrel Resistance in Stent Thrombosis (CREST) registry.
Journal: Heart (British Cardiac Society) 20120501
Title: Ticagrelor: a P2Y12 antagonist for use in acute coronary syndromes.
Journal: Expert review of clinical pharmacology 20120501
Title: Mechanisms of Platelet Activation and Integrin αIIβ3.
Journal: Korean circulation journal 20120501
Title: Cardiac dysfunction in the CABG patient.
Journal: Current opinion in pharmacology 20120401
Title: [Modern treatment in acute coronary syndrome].
Journal: Deutsche medizinische Wochenschrift (1946) 20120401
Title: Latest evidence in personalized antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary intervention.
Journal: Hospital practice (1995) 20120401
Title: Ticagrelor: a new option for ACS.
Journal: The Nurse practitioner 20120313
Title: Antiplatelet therapy: controversial aspects.
Journal: Thrombosis research 20120301
Title: [New antiplatelet agents and the question of dual antiplatelet therapy].
Journal: Der Internist 20120301
Title: Review of atrial fibrillation outcome trials of oral anticoagulant and antiplatelet agents.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120301
Title: Emerging antiplatelet therapy for coronary artery disease and acute coronary syndrome.
Journal: Pharmacotherapy 20120301
Title: Peripheral vascular outcomes in the PLATO trial: update from the FDA ticagrelor complete response review.
Journal: American journal of therapeutics 20120301
Title: Association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from the platelet inhibition and patient outcomes trial.
Journal: Circulation 20120227
Title: Ticagrelor induces adenosine triphosphate release from human red blood cells.
Journal: Biochemical and biophysical research communications 20120224
Title: Optimizing antiplatelet therapy in acute coronary syndrome and percutaneous coronary intervention.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201
Title: Antiplatelet and anticoagulant drugs in interventional radiology.
Journal: Cardiovascular and interventional radiology 20120201
Title: Antiplatelet function variability in clopidogrel-treated patients: need for new antiplatelet agents.
Journal: Fundamental & clinical pharmacology 20120201
Title: Clinical effects and outcomes with new P2Y12 inhibitors in ACS.
Journal: Fundamental & clinical pharmacology 20120201
Title: In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization.
Journal: Purinergic signalling 20120201
Title: Novel antiplatelet therapies.
Journal: Current atherosclerosis reports 20120201
Title: Pharmacokinetics and tolerability of single and multiple doses of ticagrelor in healthy Chinese subjects: an open-label, sequential, two-cohort, single-centre study.
Journal: Clinical drug investigation 20120201
Title: Antiplatelet therapy in patients with ST-elevation myocardial infarction undergoing myocardial revascularisation: beyond clopidogrel.
Journal: Current medical research and opinion 20120201
Title: P2Y12 platelet inhibition in clinical practice.
Journal: Journal of thrombosis and thrombolysis 20120201
Title: Optimal management of antiplatelet therapy and proton pump inhibition following percutaneous coronary intervention.
Journal: Current treatment options in cardiovascular medicine 20120201
Title: Management of coagulation: an Australian perspective.
Journal: Current opinion in anaesthesiology 20120201
Title: Evaluation and characterization of the effects of ticagrelor on serum and urinary uric acid in healthy volunteers.
Journal: Clinical pharmacology and therapeutics 20120201
Title: A comprehensive comparative review of adenosine diphosphate receptor antagonists.
Journal: Expert opinion on pharmacotherapy 20120201
Title: InforMatrix: ADP antagonists in acute coronary syndromes.
Journal: Expert opinion on pharmacotherapy 20120201
Title: Effect size of ticagrelor over clopidogrel in the Platelet Inhibition and Patient Outcomes (PLATO) trial: from statistics to clinical judgment.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20120201
Title: 'Conversations in cardiology': How do you pick the best antiplatelet drug--clopidogrel, prasugrel, ticagrelor for your PCI patient?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201
Title: Primary and secondary prevention of cardiovascular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Journal: Chest 20120201
Title: ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy.
Journal: Circulation 20120124
Title: No one-size-fits-all: A tailored approach to antithrombotic therapy after stent implantation.
Journal: Circulation 20120124
Title: Do aspirin and other antiplatelet drugs reduce the mortality in critically ill patients?
Journal: Thrombosis 20120101
Title: Cystatin C and estimated glomerular filtration rate as predictors for adverse outcome in patients with ST-elevation and non-ST-elevation acute coronary syndromes: results from the Platelet Inhibition and Patient Outcomes study.
Journal: Clinical chemistry 20120101
Title: Antiplatelet therapy in acute coronary syndromes.
Journal: Expert opinion on pharmacotherapy 20120101
Title: Recent advances in epidural analgesia.
Journal: Anesthesiology research and practice 20120101
Title: Bleeding tendency in dual antiplatelet therapy with aspirin/clopidogrel: rescue of the template bleeding time in a single-center prospective study.
Journal: Thrombosis journal 20120101
Title: Antiplatelet therapy in atherothrombotic cardiovascular diseases for primary and secondary prevention: a focus on old and new antiplatelet agents.
Journal: Current pharmaceutical design 20120101
Title: Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology.
Journal: Frontiers in pharmacology 20120101
Title: New perspectives in antiplatelet therapy.
Journal: Current medicinal chemistry 20120101
Title: Increased atherothrombotic burden in patients with diabetes mellitus and acute coronary syndrome: a review of antiplatelet therapy.
Journal: Cardiology research and practice 20120101
Title: A critical appraisal of the functional evolution of P2Y12 antagonists as antiplatelet drugs.
Journal: Current pharmaceutical design 20120101
Title: Evolving role of platelet function testing in coronary artery interventions.
Journal: Vascular health and risk management 20120101
Title: Who protects physicians and patients from guidelines?
Journal: Cardiology 20120101
Title: Serotonin antagonism improves platelet inhibition in clopidogrel low-responders after coronary stent placement: an in vitro pilot study.
Journal: PloS one 20120101
Title: Oral antiplatelet therapy for atherothrombotic disease: overview of current and emerging treatment options.
Journal: Vascular health and risk management 20120101
Title: [Optimal antiplatelet and antithrombotic therapy in patients with ST elevation myocardial infarction].
Journal: Kardiologia polska 20120101
Title: [Letter to Kardiologia Polska concerning optimal treatment of myocardial infarction].
Journal: Kardiologia polska 20120101
Title: The avantgarde carbostent in patients scheduled for undelayable noncardiac surgery.
Journal: Thrombosis 20120101
Title: Chinese herb and formulas for promoting blood circulation and removing blood stasis and antiplatelet therapies.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: The 'Harmonizing Optimal Strategy for Treatment of coronary artery stenosis - sAfety & effectiveneSS of drug-elUting stents & antiplatelet REgimen' (HOST-ASSURE) trial: study protocol for a randomized controlled trial.
Journal: Trials 20120101
Title: Platelet adenosine diphosphate receptor antagonists: ticlopidine to ticagrelor-a long continuing journey.
Journal: Indian heart journal 20120101
Title: Anticoagulant and antiplatelet therapy in patients with atrial fibrillation and coronary artery disease.
Journal: Thrombosis 20120101
Title: Stent thrombosis: incidence, predictors and new technologies.
Journal: Thrombosis 20120101
Title: Do Clopidogrel Nonresponders Have an Increased Risk of Adverse Events during Supra-Aortal Angioplasty and Stenting?
Journal: Stroke research and treatment 20120101
Title: [New antithrombotic drugs].
Journal: Duodecim; laaketieteellinen aikakauskirja 20120101
Title: Dabigatran for stroke prevention in nonvalvular atrial fibrillation: answers to challenging 'real-world' questions.
Journal: Thrombosis 20120101
Title: Dual thienopyridine low-response to clopidogrel and prasugrel in a patient with STEMI, cardiogenic shock and early stent thrombosis is overcome by ticagrelor.
Journal: Platelets 20120101
Title: Antiplatelet therapy - ticagrelor.
Journal: Hamostaseologie 20120101
Title: Ticagrelor FDA approval issues revisited.
Journal: Cardiology 20120101
Title: [The role of direct-acting P2Y12 inhibitors in acute coronary syndrome].
Journal: Kardiologiia 20120101
Title: Impact of antiplatelet therapy in heart disease.
Journal: Advances in cardiology 20120101
Title: Clopidogrel in coronary artery disease: update 2012.
Journal: Advances in cardiology 20120101
Title: Antiplatelet therapy in acute coronary syndromes: ticagrelor.
Journal: Advances in cardiology 20120101
Title: Genetic considerations.
Journal: Advances in cardiology 20120101
Title: Advances in the monitoring of anti-P2Y12 therapy.
Journal: Platelets 20120101
Title: Thienopyridines and other ADP-receptor antagonists.
Journal: Handbook of experimental pharmacology 20120101
Title: Intracellular signaling as a potential target for antiplatelet therapy.
Journal: Handbook of experimental pharmacology 20120101
Title: Antiplatelet therapy in peripheral artery disease.
Journal: Handbook of experimental pharmacology 20120101
Title: Antiplatelet agents and anticoagulants for hypertension.
Journal: The Cochrane database of systematic reviews 20111207
Title: Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes.
Journal: European heart journal 20111201
Title: Clopidogrel resistance: identifying and overcoming a barrier to effective antiplatelet treatment.
Journal: Cardiovascular therapeutics 20111201
Title: Pulmonary function in patients with acute coronary syndrome treated with ticagrelor or clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] pulmonary function substudy).
Journal: The American journal of cardiology 20111201
Title: Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y₁₂ antagonist ticagrelor.
Journal: Thrombosis and haemostasis 20111201
Title: Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial.
Journal: European heart journal 20111201
Title: No free lunches: balancing bleeding and efficacy with ticagrelor.
Journal: European heart journal 20111201
Title: Unravelling the benefit against the risk of long-term dual antiplatelet therapy.
Journal: Current opinion in cardiology 20111201
Title: [Who protects physicians and patients from guidelines?].
Journal: Deutsche medizinische Wochenschrift (1946) 20111201
Title: Recent advances in the management of acute myocardial infarction.
Journal: The Journal of the Association of Physicians of India 20111201
Title: Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease.
Journal: Journal of the American College of Cardiology 20111122
Title: Genetic determinants of platelet response to clopidogrel.
Journal: Journal of thrombosis and thrombolysis 20111101
Title: Role of platelet function testing in clinical practice: current concepts and future perspectives.
Journal: Current drug targets 20111101
Title: Overcoming limitations of current antiplatelet drugs: a concerted effort for more profitable strategies of intervention.
Journal: Annals of medicine 20111101
Title: Current concepts on coronary revascularization in diabetic patients.
Journal: European heart journal 20111101
Title: Treating acute coronary syndromes with new antiplatelet drugs: the mortality issue with prasugrel and ticagrelor.
Journal: Current medical research and opinion 20111101
Title: Female platelets are hard to control.
Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20111101
Title: Antiplatelet options for secondary prevention in acute coronary syndromes.
Journal: Expert review of cardiovascular therapy 20111101
Title: Evaluating the risk-benefit profile of the direct-acting P2Y(12) inhibitor ticagrelor in acute coronary syndromes.
Journal: Postgraduate medicine 20111101
Title: [New era in antiplatelet therapy based on results from recent clinical trials].
Journal: Medicina clinica 20111022
Title: Oral antiplatelet agents in ACS: from pharmacology to clinical differences.
Journal: Fundamental & clinical pharmacology 20111001
Title: Anti-platelet therapy: ADP receptor antagonists.
Journal: British journal of clinical pharmacology 20111001
Title: Genotypic and phenotypic assessment of platelet function and response to P2Y12 antagonists.
Journal: Current cardiology reports 20111001
Title: Antiplatelet effects of aspirin vary with level of P2Y₁₂ receptor blockade supplied by either ticagrelor or prasugrel.
Journal: Journal of thrombosis and haemostasis : JTH 20111001
Title: Vorapaxar: a novel protease-activated receptor-1 inhibitor.
Journal: Expert opinion on investigational drugs 20111001
Title: Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction--a hospital registry-primary care linked cohort (MINAP-GPRD).
Journal: European heart journal 20111001
Title: Use of prasugrel in a patient with clopidogrel hypersensitivity.
Journal: The Annals of pharmacotherapy 20111001
Title: Variability of clopidogrel response in patients with type 2 diabetes mellitus.
Journal: Diabetes & vascular disease research 20111001
Title: Ticagrelor. Acute coronary syndromes: nothing new.
Journal: Prescrire international 20111001
Title: Benefits of ticagrelor debated as antiplatelet class approaches generic market.
Journal: Managed care (Langhorne, Pa.) 20111001
Title: Managing adverse effects and drug-drug interactions of antiplatelet agents.
Journal: Nature reviews. Cardiology 20110913
Title: Ticagrelor (Brilinta)--better than clopidogrel (Plavix)?
Journal: The Medical letter on drugs and therapeutics 20110905
Title: Implications of variability in definition and reporting of major bleeding in randomized trials of oral P2Y12 inhibitors for acute coronary syndromes.
Journal: European heart journal 20110901
Title: Disposition and metabolism of ticagrelor, a novel P2Y12 receptor antagonist, in mice, rats, and marmosets.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110901
Title: Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses.
Journal: Journal of thrombosis and haemostasis : JTH 20110901
Title: Agreement between adjusted indirect comparison and simplified network meta-analyses on prasugrel and ticagrelor (Reply to Passaro et al. - Int J Cardiol 2011).
Journal: International journal of cardiology 20110901
Title: P2 receptors and platelet function.
Journal: Purinergic signalling 20110901
Title: P2Y₁₂ receptor inhibitors: integrating ticagrelor into the management of acute coronary syndrome.
Journal: The Annals of pharmacotherapy 20110901
Title: Ticagrelor approved for acute coronary syndrome.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110901
Title: Evaluation of the effect of dapagliflozin on cardiac repolarization: a thorough QT/QTc study.
Journal: Diabetes therapy : research, treatment and education of diabetes and related disorders 20110901
Title: Adjusted indirect comparison meta-analysis of prasugrel versus ticagrelor for patients with acute coronary syndromes.
Journal: International journal of cardiology 20110804
Title: Anti-platelet treatments in acute coronary syndrome: simplified network meta-analysis.
Journal: International journal of cardiology 20110804
Title: Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial.
Journal: Circulation 20110802
Title: P2Y12 antagonists in acute coronary syndrome: in whom should they be started, and when?
Journal: Current cardiology reports 20110801
Title: High platelet reactivity and clinical outcome - fact and fiction.
Journal: Thrombosis and haemostasis 20110801
Title: Antithrombotic management for transient ischemic attack and ischemic stroke (other than atrial fibrillation).
Journal: Current atherosclerosis reports 20110801
Title: Beyond aspirin and clopidogrel: is there a need for additional antiplatelet therapy in ACS?
Journal: Current cardiology reports 20110801
Title: Effect of ticagrelor on the pharmacokinetics of ethinyl oestradiol and levonorgestrel in healthy volunteers.
Journal: Current medical research and opinion 20110801
Title: Determination of unbound ticagrelor and its active metabolite (AR-C124910XX) in human plasma by equilibrium dialysis and LC-MS/MS.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110801
Title: Prasugrel vs. ticagrelor in acute coronary syndromes: which one to choose?
Journal: Wiener klinische Wochenschrift 20110801
Title: The future of platelet function testing to guide therapy in clopidogrel low and enhanced responders.
Journal: Expert review of cardiovascular therapy 20110801
Title: Impact of dyspnea on medical utilization and affiliated costs in patients with acute coronary syndrome.
Journal: Hospital practice (1995) 20110801
Title: Pharmacokinetics, pharmacodynamics, and safety of ticagrelor in volunteers with mild hepatic impairment.
Journal: Journal of clinical pharmacology 20110701
Title: Ischaemic and bleeding complications with new, compared to standard, ADP-antagonist regimens in acute coronary syndromes: a meta-analysis of randomized trials.
Journal: QJM : monthly journal of the Association of Physicians 20110701
Title: The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies.
Journal: American heart journal 20110701
Title: [Ticagrelor: a novel antiplatelet agent for patients with acute coronary syndrome].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20110701
Title: Non-interventional management of acute coronary syndromes.
Journal: BMJ (Clinical research ed.) 20110617
Title: How to explain the reduced cardiovascular mortality in the ticagrelor arm of the PLATO trial?
Journal: International journal of cardiology 20110602
Title: Novel antiplatelet agent ticagrelor in the management of acute coronary syndrome.
Journal: Journal of interventional cardiology 20110601
Title: Beyond efficacy: pharmacokinetic differences between clopidogrel, prasugrel and ticagrelor.
Journal: Expert opinion on pharmacotherapy 20110601
Title: Usefulness of a nanoparticle formulation to investigate some hemodynamic parameters of a poorly soluble compound.
Journal: Journal of pharmaceutical sciences 20110601
Title: [Myocardial infarction: Role of new antiplatelet agents].
Journal: Presse medicale (Paris, France : 1983) 20110601
Title: [Update on anti-platelet therapy].
Journal: Deutsche medizinische Wochenschrift (1946) 20110601
Title: Ticagrelor for acute coronary syndrome?
Journal: Drug and therapeutics bulletin 20110601
Title: Ticagrelor versus genotype-driven antiplatelet therapy for secondary prevention after acute coronary syndrome: a cost-effectiveness analysis.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110601
Title: The incidence of bradyarrhythmias and clinical bradyarrhythmic events in patients with acute coronary syndromes treated with ticagrelor or clopidogrel in the PLATO (Platelet Inhibition and Patient Outcomes) trial: results of the continuous electrocardiographic assessment substudy.
Journal: Journal of the American College of Cardiology 20110510
Title: Ticagrelor: a review of its use in the management of acute coronary syndromes.
Journal: Drugs 20110507
Title: [New approaches and indications for the analysis of platelet function in cardiology].
Journal: Hamostaseologie 20110502
Title: Viewpoint: paradoxical excess mortality in the PLATO trial should be independently verified.
Journal: Thrombosis and haemostasis 20110501
Title: Explaining the unexpected: insights from the PLATelet inhibition and clinical Outcomes (PLATO) trial comparing ticagrelor and clopidogrel. Editorial on Serebruany 'Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified' (Thromb Haemost 2011; 105.5).
Journal: Thrombosis and haemostasis 20110501
Title: The PLATO trial reveals further opportunities to improve outcomes in patients with acute coronary syndrome. Editorial on Serebruany. 'Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified' (Thromb Haemost 2011; 105.5).
Journal: Thrombosis and haemostasis 20110501
Title: Bleeding manifestations of congenital and drug-induced defects of the platelet P2Y12 receptor for adenosine diphosphate.
Journal: Thrombosis and haemostasis 20110501
Title: Pharmacology and clinical trials of reversibly-binding P2Y12 inhibitors.
Journal: Thrombosis and haemostasis 20110501
Title: [Coronary stent thrombosis: what's new in 2011?].
Journal: Herz 20110501
Title: Advances in cardiology: clinical trial update.
Journal: Future cardiology 20110501
Title: In vitro evaluation of potential drug-drug interactions with ticagrelor: cytochrome P450 reaction phenotyping, inhibition, induction, and differential kinetics.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110401
Title: Fresh from the pipeline. Ticagrelor.
Journal: Nature reviews. Drug discovery 20110401
Title: [Do genetic factors reduce the effects of clopidogrel?].
Journal: Deutsche medizinische Wochenschrift (1946) 20110401
Title: [Recent advances on the studies of the platelet's inhibition and aggregation. State of the art of new P2Y12 antagonists].
Journal: Recenti progressi in medicina 20110401
Title: Oral antiplatelet therapy for atherothrombotic disease: current evidence and new directions.
Journal: American heart journal 20110301
Title: The platelet P2Y₁₂ receptor for adenosine diphosphate: congenital and drug-induced defects.
Journal: Blood 20110217
Title: Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: results from the PLATO (Platelet Inhibition and Patient Outcomes) trial.
Journal: Journal of the American College of Cardiology 20110208
Title: Mechanisms potentially contributing to the reduction in mortality associated with ticagrelor therapy.
Journal: Journal of the American College of Cardiology 20110208
Title: Allergic reactions to clopidogrel and cross-reactivity to other agents.
Journal: Current allergy and asthma reports 20110201
Title: Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20110201
Title: Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling.
Journal: Journal of thrombosis and haemostasis : JTH 20110201
Title: Antiplatelet drugs: a review of their pharmacology and management in the perioperative period.
Journal: Anesthesia and analgesia 20110201
Title: Antithrombotic therapy in ST-segment elevation myocardial infarction.
Journal: Expert opinion on pharmacotherapy 20110201
Title: Overview of the 2010 Food and Drug Administration Cardiovascular and Renal Drugs Advisory Committee meeting regarding ticagrelor.
Journal: Circulation 20110201
Title: Resistance to anti-platelet agents.
Journal: Thrombosis research 20110201
Title: [Coronary heart disease - what is of importance after coronary intervention?].
Journal: Deutsche medizinische Wochenschrift (1946) 20110201
Title: Ticagrelor: from concept to clinical evaluation.
Journal: Biomarkers in medicine 20110201
Title: Mode of action of P2Y(12 ) antagonists as inhibitors of platelet function.
Journal: Thrombosis and haemostasis 20110101
Title: Adenosine release: a potential explanation for the benefits of ticagrelor in the PLATelet inhibition and clinical outcomes trial?
Journal: American heart journal 20110101
Title: Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium.
Journal: European heart journal 20110101
Title: Pharmacogenetics: Ticagrelor superior to clopidogrel in individuals predicted to be clopidogrel responders.
Journal: Nature reviews. Cardiology 20110101
Title: Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance--the BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy.
Journal: BMC medicine 20110101
Title: Ticagrelor: a novel reversible oral antiplatelet agent.
Journal: Cardiology in review 20110101
Title: Antiplatelet combinations for prevention of atherothrombotic events.
Journal: Vascular health and risk management 20110101
Title: Ticagrelor: the evidence for its clinical potential as an oral antiplatelet treatment for the reduction of major adverse cardiac events in patients with acute coronary syndromes.
Journal: Core evidence 20110101
Title: P2Y receptors in health and disease.
Journal: Advances in pharmacology (San Diego, Calif.) 20110101
Title: P2Y₁₂ and EP3 antagonists promote the inhibitory effects of natural modulators of platelet aggregation that act via cAMP.
Journal: Platelets 20110101
Title: Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial.
Journal: BMJ (Clinical research ed.) 20110101
Title: Diabetes mellitus and cardiovascular prevention: the role and the limitations of currently available antiplatelet drugs.
Journal: International journal of vascular medicine 20110101
Title: Effect of proton pump inhibitors on platelet inhibition activity of clopidogrel in Chinese patients with percutaneous coronary intervention.
Journal: Vascular health and risk management 20110101
Title: Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis.
Journal: BMJ (Clinical research ed.) 20110101
Title: Oral antiplatelet therapy in diabetes mellitus and the role of prasugrel: an overview.
Journal: Vascular health and risk management 20110101
Title: Between-centre differences and treatment effects in randomized controlled trials: a case study in traumatic brain injury.
Journal: Trials 20110101
Title: Platelet function in patients with diabetes mellitus: from a theoretical to a practical perspective.
Journal: International journal of endocrinology 20110101
Title: The use of ticagrelor in a patient at increased risk of stent thrombosis resistant to multiple thienopyridines.
Journal: Cardiology 20110101
Title: Emerging therapies for acute coronary syndromes.
Journal: Frontiers in pharmacology 20110101
Title: Novel agents for anti-platelet therapy.
Journal: Journal of hematology & oncology 20110101
Title: Rivaroxaban, ticagrelor, and fidaxomicin.
Journal: Journal of the American Pharmacists Association : JAPhA 20110101
Title: Optimizing antiplatelet therapy following percutaneous coronary intervention: clinical pathways for platelet function testing.
Journal: Reviews in cardiovascular medicine 20110101
Title: Current options in oral antiplatelet strategies during percutaneous coronary interventions.
Journal: Reviews in cardiovascular medicine 20110101
Title: Post percutaneous coronary intervention antiplatelet therapy: current perceptions, prospects and perplexity.
Journal: Cardiology journal 20110101
Title: Gene-drug interaction in stroke.
Journal: Stroke research and treatment 20110101
Title: Advances in antiplatelet therapy.
Journal: Hematology. American Society of Hematology. Education Program 20110101
Title: Critical appraisal of ticagrelor in the management of acute coronary syndrome.
Journal: Therapeutics and clinical risk management 20110101
Title: [The effectiveness of Ticagrelor does not depend on CYP2C19 gene polymorphism and ABCB1: results of a genetic analysis of the study PLATO].
Journal: Kardiologiia 20110101
Title: The FDA outlook of events reporting after ticagrelor or clopidogrel in the PLATO Trial: impact of sponsor censoring dates, drug discontinuation, and withdrawal of consent.
Journal: Cardiology 20110101
Title: Cytochrome P450 2C19 Polymorphism in Iranian Patients with Coronary Artery Disease.
Journal: ARYA atherosclerosis 20110101
Title: Ticagrelor vs. clopidogrel in patients with acute coronary syndromes and diabetes: a substudy from the PLATelet inhibition and patient Outcomes (PLATO) trial.
Journal: European heart journal 20101201
Title: Diabetics with acute coronary syndrome: advances, challenges, and uncertainties.
Journal: European heart journal 20101201
Title: Ticagrelor effectively and reversibly blocks murine platelet P2Y12-mediated thrombosis and demonstrates a requirement for sustained P2Y12 inhibition to prevent subsequent neointima.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20101201
Title: Is ticagrelor the antiplatelet therapy panacea?
Journal: Circulation. Cardiovascular genetics 20101201
Title: First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.
Journal: Circulation. Cardiovascular genetics 20101201
Title: Ticagrelor to prevent restenosis: new drug for an old hypothesis?
Journal: Arteriosclerosis, thrombosis, and vascular biology 20101201
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20101201
Title: [Antiplatelet agents in acute coronary syndromes. Data from the main clinical trials].
Journal: Annales de cardiologie et d'angeiologie 20101201
Title: [Antiplatelet agents and diabetes mellitus].
Journal: Annales de cardiologie et d'angeiologie 20101201
Title: [Current options to manage clopidogrel poor responsiveness].
Journal: Giornale italiano di cardiologia (2006) 20101201
Title: [Antiplatelet therapy in acute coronary syndromes: state of the art and new perspectives].
Journal: Giornale italiano di cardiologia (2006) 20101201
Title: Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis.
Journal: Circulation 20101123
Title: Double-blind, placebo-controlled Phase II studies of the protease-activated receptor 1 antagonist E5555 (atopaxar) in Japanese patients with acute coronary syndrome or high-risk coronary artery disease.
Journal: European heart journal 20101101
Title: A new era for antiplatelet therapy in patients with acute coronary syndrome.
Journal: The American journal of the medical sciences 20101101
Title: Ticagrelor and prasugrel: two novel, most-promising antiplatelet agents.
Journal: Recent patents on cardiovascular drug discovery 20101101
Title: Dual antiplatelet therapy in cardiovascular disease: does aspirin increase clinical risk in the presence of potent P2Y12 receptor antagonists?
Journal: Heart (British Cardiac Society) 20101101
Title: Emerging oral antiplatelet therapies for acute coronary syndromes.
Journal: Hospital practice (1995) 20101101
Title: Clinical impact of enhanced inhibition of P2Y12-mediated platelet aggregation in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention.
Journal: Hospital practice (1995) 20101101
Title: Ticagrelor: a novel oral antiplatelet agent.
Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20101101
Title: Ticagrelor: from discovery to Phase III clinical trial.
Journal: Future cardiology 20101101
Title: Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: the PLATO (PLATelet inhibition and patient Outcomes) PLATELET substudy.
Journal: Journal of the American College of Cardiology 20101026
Title: Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial.
Journal: Lancet (London, England) 20101016
Title: Antiplatelet therapy in acute coronary syndrome (ACS): applying new science to clinical decisions.
Journal: The American journal of cardiology 20101015
Title: State of the art of new P2Y12 antagonists.
Journal: Internal and emergency medicine 20101001
Title: Emerging antithrombotic agents: what does the intensivist need to know?
Journal: Current opinion in critical care 20101001
Title: Single-dose ticagrelor does not prolong the QT interval in healthy subjects.
Journal: International journal of clinical pharmacology and therapeutics 20101001
Title: Genetic testing for CYP450 polymorphisms to predict response to clopidogrel: current evidence and test availability. Application: pharmacogenomics.
Journal: PLoS currents 20100920
Title: Ticagrelor in the renal dysfunction subgroup: subjugated or substantiated?
Journal: Circulation 20100914
Title: Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial.
Journal: Circulation 20100914
Title: Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901
Title: New antithrombotic agents--insights from clinical trials.
Journal: Nature reviews. Cardiology 20100901
Title: Determination of ticagrelor and two metabolites in plasma samples by liquid chromatography and mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100901
Title: Adjunctive treatment with ticagrelor, but not clopidogrel, added to tPA enables sustained coronary artery recanalisation with recovery of myocardium perfusion in a canine coronary thrombosis model.
Journal: Thrombosis and haemostasis 20100901
Title: Ticagrelor for the treatment of arterial thrombosis.
Journal: Expert opinion on pharmacotherapy 20100901
Title: Balancing the benefits and risks of antiplatelet agents in patients with non-ST-segment elevated acute coronary syndromes and undergoing percutaneous coronary intervention.
Journal: Journal of thrombosis and thrombolysis 20100801
Title: Recent therapeutic approaches to platelet activation in coronary artery disease.
Journal: Pharmacology & therapeutics 20100801
Title: Current strategies in antiplatelet therapy--does identification of risk and adjustment of therapy contribute to more effective, personalized medicine in cardiovascular disease?
Journal: Pharmacology & therapeutics 20100801
Title: Oral antiplatelet therapy after acute coronary syndrome and percutaneous coronary intervention: balancing efficacy and bleeding risk.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100801
Title: Pharmacologic therapy for non ST-segment elevation acute coronary syndromes: focus on antithrombotic therapy.
Journal: Cardiovascular drugs and therapy 20100801
Title: Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study.
Journal: Journal of the American College of Cardiology 20100713
Title: The reversible oral P2Y12 antagonist AZD6140 inhibits ADP-induced contractions in murine and human vasculature.
Journal: International journal of cardiology 20100709
Title: The case for routine genotyping in dual-antiplatelet therapy.
Journal: Journal of the American College of Cardiology 20100706
Title: The role of antiplatelet therapy in the secondary prevention of coronary artery disease.
Journal: Current opinion in cardiology 20100701
Title: Examining biology and pharmacology-based hypotheses in the PLATO trial.
Journal: Journal of thrombosis and thrombolysis 20100701
Title: Antiplatelet therapy in percutaneous coronary intervention: recent advances in oral antiplatelet agents.
Journal: Current opinion in cardiology 20100701
Title: PLATO study of ticagrelor versus clopidogrel in patients with high-risk acute coronary syndromes.
Journal: Current cardiology reports 20100701
Title: What goes into a major acute coronary syndrome trial and what will future trials look like?
Journal: Current cardiology reports 20100701
Title: Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers.
Journal: British journal of clinical pharmacology 20100701
Title: [Novel agents in antiplatelet therapy].
Journal: Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20100701
Title: Alternatives to clopidogrel for acute coronary syndromes: Prasugrel or ticagrelor?
Journal: World journal of cardiology 20100626
Title: The state of periprocedural antiplatelet therapy after recent trials.
Journal: JACC. Cardiovascular interventions 20100601
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20100601
Title: The year in interventional cardiology.
Journal: Journal of the American College of Cardiology 20100518
Title: ACP Journal Club. Ticagrelor was more effective than clopidogrel in acute coronary syndromes with planned invasive treatment.
Journal: Annals of internal medicine 20100518
Title: Antiplatelet drugs--do we need new options? With a reappraisal of direct thromboxane inhibitors.
Journal: Drugs 20100507
Title: Advances in antiplatelet treatment for acute coronary syndromes.
Journal: Heart (British Cardiac Society) 20100501
Title: Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y(12) receptor antagonist, in healthy subjects.
Journal: European journal of clinical pharmacology 20100501
Title: [The PLATO study].
Journal: Giornale italiano di cardiologia (2006) 20100501
Title: Recent research on antithrombotics. News on the treatment of patients with acute coronary syndromes.
Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20100501
Title: The PLATO trial: do you believe in magic?
Journal: European heart journal 20100401
Title: Antiplatelet therapy prasugrel: a novel platelet ADP P2Y12 receptor antagonist.
Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20100401
Title: [Update: oral platelet inhibitors in cardiology].
Journal: Der Internist 20100401
Title: Changes in inflammatory biomarkers in patients treated with ticagrelor or clopidogrel.
Journal: Clinical cardiology 20100401
Title: Ticagrelor.
Journal: Drugs of today (Barcelona, Spain : 1998) 20100401
Title: Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study.
Journal: Circulation 20100316
Title: Role of ticagrelor in clopidogrel nonresponders: resistance is futile?
Journal: Circulation 20100316
Title: The novel P2Y 12 antagonist AZD6140 rapidly and reversibly reduces platelet activation in diabetic rats.
Journal: Thrombosis research 20100301
Title: Efficacy and safety of ticagrelor: a reversible P2Y12 receptor antagonist.
Journal: The Annals of pharmacotherapy 20100301
Title: Advances in antiplatelet therapy for stroke prevention: the new P2Y12 antagonists.
Journal: Current drug targets 20100301
Title: Management of antiplatelet therapy during acute percutaneous coronary intervention: new strategies and therapeutics.
Journal: Annals of the Academy of Medicine, Singapore 20100301
Title: The TRITON versus PLATO trials: differences beyond platelet inhibition.
Journal: Thrombosis and haemostasis 20100201
Title: Pharmacokinetic, pharmacodynamic and clinical profile of novel antiplatelet drugs targeting vascular diseases.
Journal: British journal of pharmacology 20100201
Title: New drugs for the treatment of coronary artery syndromes: otamixaban and ticagrelor.
Journal: Expert opinion on pharmacotherapy 20100201
Title: Limitations of current therapies to prevent thrombosis: a need for novel strategies.
Journal: Molecular bioSystems 20100201
Title: The year in cardiothoracic and vascular anesthesia: selected highlights from 2009.
Journal: Journal of cardiothoracic and vascular anesthesia 20100201
Title: Mechanism of action and clinical development of ticagrelor, a novel platelet ADP P2Y12 receptor antagonist.
Journal: Expert review of cardiovascular therapy 20100201
Title: Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study.
Journal: Lancet (London, England) 20100123
Title: Ticagrelor in ACS: redefining a new standard of care?
Journal: Lancet (London, England) 20100123
Title: [Update on new antithrombotic treatments].
Journal: Revue medicale suisse 20100120
Title: Emerging P2Y12 receptor antagonists: role in coronary artery disease.
Journal: Current vascular pharmacology 20100101
Title: Recent advances in cardiology.
Journal: Future cardiology 20100101
Title: [Ticagrelor versus clopidogrel in patients with acute coronary syndromes: results of the PLATO study].
Journal: Kardiologiia 20100101
Title: Stabilizing role of platelet P2Y(12) receptors in shear-dependent thrombus formation on ruptured plaques.
Journal: PloS one 20100101
Title: Ticagrelor, a new antiplatelet agent, for prevention of ischemic events in patients with coronary artery disease.
Journal: Current neurology and neuroscience reports 20100101
Title: Forecasting drug utilization and expenditure in a metropolitan health region.
Journal: BMC health services research 20100101
Title: Novel antiplatelet agents in the prevention of cardiovascular complications--focus on ticagrelor.
Journal: Vascular health and risk management 20100101
Title: Prasugrel: a novel platelet ADP P2Y(12) receptor antagonist.
Journal: Methods in molecular biology (Clifton, N.J.) 20100101
Title: [Antiplatelet therapy in coronary heart disease. Some problems and achivements].
Journal: Kardiologiia 20100101
Title: News and views from the literature. Antiplatelet therapy. Ticagrelor in acute coronary syndrome: a new frontier in platelet inhibition.
Journal: Reviews in cardiovascular medicine 20100101
Title: Antithrombotics in acute coronary syndromes: updates from the past year.
Journal: Current treatment options in cardiovascular medicine 20100101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20100101
Title: Antithrombotic strategies in patients undergoing percutaneous coronary intervention for acute coronary syndrome.
Journal: Drug design, development and therapy 20100101
Title: Ticagrelor: an investigational oral antiplatelet treatment for reduction of major adverse cardiac events in patients with acute coronary syndrome.
Journal: Vascular health and risk management 20100101
Title: Anti-platelet therapy and aspirin resistance - clinically and chemically relevant?
Journal: Current medicinal chemistry 20100101
Title: Current concepts on antiplatelet therapy: focus on the novel thienopyridine and non-thienopyridine agents.
Journal: Advances in hematology 20100101
Title: Clopidogrel: a pharmacogenomic perspective on its use in coronary artery disease.
Journal: Clinical Medicine Insights. Cardiology 20100101
Title: Mortality benefit in PLATO cannot be explained by antiplatelet properties of ticagrelor.
Journal: Cardiology 20100101
Title: New antiplatelet agents.
Journal: Acta anaesthesiologica Belgica 20100101
Title: Aspirin dose and ticagrelor benefit in PLATO: fact or fiction?
Journal: Cardiology 20100101
Title: Newer antithrombotic drugs.
Journal: Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20100101
Title: Interaction between clopidogrel and proton-pump inhibitors and management strategies in patients with cardiovascular diseases.
Journal: Drug, healthcare and patient safety 20100101
Title: Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of Ticagrelor versus Clopidogrel in patients with stable coronary artery disease. The ONSET/OFFSET study.
Journal: Maedica 20100101
Title: Emerging antiplatelet agents, differential pharmacology, and clinical utility.
Journal: Journal of blood medicine 20100101
Title: Antiplatelet therapy in acute coronary syndromes: focus on ticagrelor.
Journal: Journal of blood medicine 20100101
Title: The interaction between clopidogrel and proton pump inhibitors (PPI): is there any clinical relevance?
Journal: Clinical pharmacology : advances and applications 20100101
Title: Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.
Journal: Circulation 20091222
Title: ACP Journal Club. Ticagrelor was more effective than clopidogrel, with no increase in major bleeding in acute coronary syndromes.
Journal: Annals of internal medicine 20091215
Title: Ticagrelor versus clopidogrel in acute coronary syndromes.
Journal: The New England journal of medicine 20091210
Title: Ticagrelor versus clopidogrel in acute coronary syndromes.
Journal: The New England journal of medicine 20091210
Title: Ticagrelor versus clopidogrel in acute coronary syndromes.
Journal: The New England journal of medicine 20091210
Title: Ticagrelor versus clopidogrel in acute coronary syndromes.
Journal: The New England journal of medicine 20091210
Title: Oral antiplatelet therapy for acute and chronic management of NSTE ACS: residual ischemic risk and opportunities for improvement.
Journal: Cardiovascular drugs and therapy 20091201
Title: New antiplatelet agents: why they are needed.
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