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2753-30-2,MFCD01750174
Catalog No.:AA00C4FX

2753-30-2 | Gedunin

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C4FX
Chemical Name:
Gedunin
CAS Number:
2753-30-2
Molecular Formula:
C28H34O7
Molecular Weight:
482.5654
MDL Number:
MFCD01750174
SMILES:
CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@@]2([C@@H]2[C@]1(C)[C@@]13O[C@@H]1C(=O)O[C@H]([C@@]3(CC2)C)c1ccoc1)C
Properties
Computed Properties
 
Complexity:
1030  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
3  
XLogP3:
4.2  

Literature

Title: Hsp90 Co-chaperone p23 contributes to dopaminergic mitochondrial stress via stabilization of PHD2: Implications for Parkinson's disease.

Journal: Neurotoxicology 20180301

Title: Gedunin and photogedunin of Xylocarpus granatum possess antifilarial activity against human lymphatic filarial parasite Brugia malayi in experimental rodent host.

Journal: Parasitology research 20111101

Title: Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators.

Journal: Chemistry & biology 20110624

Title: Cytotoxic and apoptosis-inducing activities of limonoids from the seeds of Azadirachta indica (neem).

Journal: Journal of natural products 20110425

Title: A systematic protocol for the characterization of Hsp90 modulators.

Journal: Bioorganic & medicinal chemistry 20110101

Title: Antiplasmodial triterpenoids from the fruits of neem, Azadirachta indica.

Journal: Journal of natural products 20100827

Title: Gedunin and photogedunin of Xylocarpus granatum show significant anti-secretory effects and protect the gastric mucosa of peptic ulcer in rats.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100701

Title: Neuroprotective activity and evaluation of Hsp90 inhibitors in an immortalized neuronal cell line.

Journal: Bioorganic & medicinal chemistry 20090215

Title: Effects of limonoids from Cipadessa fruticosa on fall armyworm.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101

Title: A novel high-throughput screening assay for putative antidiabetic agents through PPARalpha interactions.

Journal: Journal of biomolecular screening 20081001

Title: Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.

Journal: Cancer cell 20061001

Title: The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Journal: Science (New York, N.Y.) 20060929

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Antioxidant and insect growth regulatory activities of stilbenes and extracts from Yucca periculosa.

Journal: Phytochemistry 20030901

Title: 6beta-hydroxygedunin from Azadirachta indica. Its potentiation effects with some non-azadirachtin limonoids in neem against lepidopteran larvae.

Journal: Journal of agricultural and food chemistry 20030507

Title: Insect antifeedant activity of tetranortriterpenoids from the Rutales. A perusal of structural relations.

Journal: Journal of agricultural and food chemistry 20020731

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