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2782-91-4,MFCD00008324
Catalog No.:AA002US5

2782-91-4 | Tetramethylthiourea

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500g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA002US5
Chemical Name:
Tetramethylthiourea
CAS Number:
2782-91-4
Molecular Formula:
C5H12N2S
Molecular Weight:
132.2272
MDL Number:
MFCD00008324
SMILES:
CN(C(=S)N(C)C)C
NSC Number:
102499
Properties
Properties
 
BP:
245°C at 760 mmHg  
Form:
Solid  
MP:
75-77 °C(lit.)  
Refractive Index:
1.5300 (estimate)  
Solubility:
32g/l  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
78.4  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
XLogP3:
0.5  

Downstream Synthesis Route

[1]Bierbach,Ulrich;Barklage,Walter;Saak,Wolfgang;Pohl,Siegfried[ZeitschriftfurNaturforschung,B:ChemicalSciences,1992,vol.47,#11,p.1593-1601]

[2]Sahasrabudhey[JournaloftheIndianChemicalSociety,1951,vol.28,p.342]

[1]Aoyagi,Naoto;Endo,Takeshi;Furusho,Yoshio[Synthesis,2020,vol.52,#1,p.150-158]

[2]Sabot,Cyrille;Kumar,KanduluruAnanda;Antheaume,Cyril;Mioskowski,Charles[JournalofOrganicChemistry,2007,vol.72,#13,p.5001-5004]

[3]Fujisaki,Shizuo;Fujiwara,Isamu;Norisue,Yasumasa;Kajigaeshi,Shoji[BulletinoftheChemicalSocietyofJapan,1985,vol.58,#8,p.2429-2430]

[4]Kondo,Yasuhiko;Yamada,Tetsuya;Kusabayashi,Shigekazu[JournaloftheChemicalSociety.PerkintransactionsII,1981,p.414-418]

[5]Lecher;Heuck[JustusLiebigsAnnalenderChemie,1924,vol.438,p.181]

[6]Hanson,P.;Williams,D.A.R.[JournaloftheChemicalSociety.PerkintransactionsII,1973,p.2162-2165]

[7]Yamaguchi,T.etal.[BulletinoftheChemicalSocietyofJapan,1968,vol.41,p.673-676]

[8]Arbelot,M.;Allouche,A.;Purcell,K.F.;Chanon,M.[JournalofOrganicChemistry,1995,vol.60,#8,p.2330-2343]

[9]Zábranský,Martin;Machara,Aleš;Císařová,Ivana;Štěpnička,Petr[EuropeanJournalofInorganicChemistry,2017,vol.2017,#41,p.4850-4860]

[1]Neuhaus,JamesD.;Angyal,Peter;Oost,Rik;Maulide,Nuno[JournalofOrganicChemistry,2018,vol.83,#4,p.2479-2485]

[2]Lloyd,D.etal.[Tetrahedron,1977,vol.33,p.1379-1389]

[3]Gronski,P.etal.[ChemischeBerichte,1977,vol.110,p.3689-3702]

[4]Arduengo,A.J.;Burgess,E.M.[JournaloftheAmericanChemicalSociety,1976,vol.98,p.5020-5021]

[1]Tyrra,Wieland[HeteroatomChemistry,2002,vol.13,#6SPEC.,p.561-566]

[2]Fawcett,F.S.etal.[JournaloftheAmericanChemicalSociety,1962,vol.84,p.4275-4285]

2782-91-4    105-36-2   
2-(2-ethoxy-2-oxoethyl)-1,1,3,3-tetramethylthiouroniumbromide 

[1]Neuhaus,JamesD.;Angyal,Peter;Oost,Rik;Maulide,Nuno[JournalofOrganicChemistry,2018,vol.83,#4,p.2479-2485]

[2]Mitamura,S.etal.[BulletinoftheChemicalSocietyofJapan,1974,vol.47,p.3152-3157]

[3]Takaku,M.etal.[TetrahedronLetters,1969,p.3651-3652]

Literature

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Journal: Dalton transactions (Cambridge, England : 2003) 20120921

Title: Thermodynamic and kinetic behaviour of [Pt(2-methylthiomethylpyridine)(OH2)2]2+.

Journal: Dalton transactions (Cambridge, England : 2003) 20120114

Title: S-oxygenation of thiocarbamides IV: Kinetics of oxidation of tetramethylthiourea by aqueous bromine and acidic bromate.

Journal: The journal of physical chemistry. A 20110407

Title: Dicyanidobis(N,N'-dimethythio-urea-κS)mercury(II).

Journal: Acta crystallographica. Section E, Structure reports online 20100901

Title: Dibromidobis(N,N,N',N'-tetra-methyl-thio-urea-κS)cadmium(II).

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Diiodidobis(N,N,N',N'-tetra-methyl-thio-urea-κS)cadmium(II).

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Dichloridobis(N,N,N',N'-tetra-methyl-thio-urea-κS)mercury(II).

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Dicyanidobis(thio-urea-κS)cadmium(II) monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Tuning the reactivity of chelated dinuclear Pt(II) complexes through a flexible diamine linker. A detailed kinetic and mechanistic study.

Journal: Dalton transactions (Cambridge, England : 2003) 20100421

Title: Platinum(II) mediated C(sp3)-H activation of tetramethylthiourea.

Journal: Dalton transactions (Cambridge, England : 2003) 20091014

Title: Mixed adsorption layers of 0.1 M tert-butanol-tetramethylthiourea at the interface of Hg/aqueous perchlorate solutions.

Journal: Journal of colloid and interface science 20090415

Title: Controlling the extent of pi-backbonding in platinum(ii) terpyridyl systems: a detailed kinetic, mechanistic and computational approach.

Journal: Dalton transactions (Cambridge, England : 2003) 20081221

Title: DNA-binding activity of NF-kappaB and phosphorylation of p65 are induced by N-acetylcysteine through phosphatidylinositol (PI) 3-kinase.

Journal: Molecular immunology 20080901

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Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060401

Title: Studies on the goitrogenic mechanism of action of N,N,N',N'-tetramethylthiourea.

Journal: Toxicology 20060116

Title: Structural modifications of aqueous ionic micelles in the presence of denaturants as studied by DLS and viscometry.

Journal: Langmuir : the ACS journal of surfaces and colloids 20051011

Title: Transforming growth factor-beta1 drives airway remodeling in cigarette smoke-exposed tracheal explants.

Journal: American journal of respiratory cell and molecular biology 20051001

Title: Air pollution particles activate NF-kappaB on contact with airway epithelial cell surfaces.

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Title: Use of a stopped-flow technique for investigation and determination of thiourea and its N-methyl derivatives as inducers of the iodine-azide reaction.

Journal: Analytical and bioanalytical chemistry 20050801

Title: Tetramethyl thiourea/Co2(CO)8-catalyzed Pauson-Khand reaction under balloon pressure of CO.

Journal: Organic letters 20050217

Title: An electrochemical quartz crystal microbalance study of the etching of gold surfaces in the presence of tetramethylthiourea.

Journal: Journal of colloid and interface science 20041101

Title: Role of chelate substituents and cis sigma-effect on the rate of ligand substitution at Pt(N-N-N) and Pt(N-N-C) centres.

Journal: Dalton transactions (Cambridge, England : 2003) 20040121

Title: Cigarette smoke produces airway wall remodeling in rat tracheal explants.

Journal: American journal of respiratory and critical care medicine 20031115

Title: Cyclometalated analogues of platinum terpyridine complexes: kinetic study of the strong sigma-donor cis and trans effects of carbon in the presence of a pi-acceptor ligand backbone.

Journal: Inorganic chemistry 20031006

Title: Air pollution particles produce airway wall remodeling in rat tracheal explants.

Journal: American journal of respiratory cell and molecular biology 20030901

Title: Redox regulation of HIF-1alpha levels and HO-1 expression in renal medullary interstitial cells.

Journal: American journal of physiology. Renal physiology 20030601

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Title: Chalcogenide-Lewis acid mediated reactions of electron-deficient alkynes with aldehydes.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20030404

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Journal: Inorganic chemistry 20030310

Title: Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate.

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