Home Other Building Blocks 2826-26-8
2826-26-8,MFCD00019787
Catalog No.:AA007KXY

2826-26-8 | Propanedinitrile,2-[(4-methoxyphenyl)methylene]-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$95.00   $67.00
- +
5g
98%
in stock  
$311.00   $218.00
- +
10g
98%
in stock  
$378.00   $264.00
- +
25g
98%
in stock  
$809.00   $567.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007KXY
Chemical Name:
Propanedinitrile,2-[(4-methoxyphenyl)methylene]-
CAS Number:
2826-26-8
Molecular Formula:
C11H8N2O
Molecular Weight:
184.1940
MDL Number:
MFCD00019787
SMILES:
COc1ccc(cc1)C=C(C#N)C#N
Properties
Computed Properties
 
Complexity:
289  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
2  

Literature

Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

Journal: The Biochemical journal 20130415

Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Journal: Nature biotechnology 20111101

Title: Growth factor/growth factor receptor loops in autocrine growth regulation of human prostate cancer DU145 cells.

Journal: Acta biochimica Polonica 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301

Title: BFA-induced compartments from the Golgi apparatus and trans-Golgi network/early endosome are distinct in plant cells.

Journal: The Plant journal : for cell and molecular biology 20091201

Title: Regulation of store-operated Ca2+ entry in pulmonary artery smooth muscle cells.

Journal: Cell calcium 20090801

Title: Basic fibroblast growth factor increases intracellular magnesium concentration through the specific signaling pathways.

Journal: Molecules and cells 20090731

Title: 3,5-Bis(4-methoxy-phen-yl)-1H-1,2,4-triazole monohydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20090601

Title: Protein tyrosine kinases and protein tyrosine phosphatases are involved in abscisic acid-dependent processes in Arabidopsis seeds and suspension cells.

Journal: Plant physiology 20081101

Title: Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes.

Journal: Pflugers Archiv : European journal of physiology 20080601

Title: Effects of tyrosine kinase and phosphatase inhibitors on microtubules in Arabidopsis root cells.

Journal: Cell biology international 20080601

Title: Molecular basis for genistein-induced inhibition of Kir2.3 currents.

Journal: Pflugers Archiv : European journal of physiology 20080501

Title: Differential effects of intravenous anesthetics on capacitative calcium entry in human pulmonary artery smooth muscle cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080501

Title: The plant defense elicitor cryptogein stimulates clathrin-mediated endocytosis correlated with reactive oxygen species production in bright yellow-2 tobacco cells.

Journal: Plant physiology 20080301

Title: S-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-O-methyltransferase.

Journal: The Journal of biological chemistry 20071019

Title: Rapid regulation of dopamine transporters by tyrosine kinases in rat neuronal preparations.

Journal: Journal of neurochemistry 20070601

Title: Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs.

Journal: Biochimica et biophysica acta 20061001

Title: Vascular endothelial growth factor increases the intracellular magnesium.

Journal: Biochemical and biophysical research communications 20060825

Title: Mitogen-activated protein kinase is involved in the progesterone-mediated induction of baboon glycodelin.

Journal: Endocrine 20060201

Title: Swelling-activated K+ efflux and regulatory volume decrease efficiency in human bronchial epithelial cells.

Journal: The Journal of membrane biology 20060101

Title: Assigning functions to distinct regions of the N-terminus of the prion protein that are involved in its copper-stimulated, clathrin-dependent endocytosis.

Journal: Journal of cell science 20051101

Title: Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury.

Journal: American journal of respiratory and critical care medicine 20050415

Title: Intracellular protein phosphorylation in adherent U937 monocytes mediated by various culture conditions and fibronectin-derived surface ligands.

Journal: Biomaterials 20050301

Title: Genistein reduces agonist-induced contractions of porcine coronary arterial smooth muscle in a cyclic AMP-dependent manner.

Journal: European journal of pharmacology 20041025

Title: [Construction of a three-dimensional human angiogenesis model in vitro for antiangiogenic drug selection].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20041001

Title: The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801

Title: Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.

Journal: European journal of endocrinology 20040801

Title: Modulations of shear stress-induced contractile responses and agonist-induced vasodilation in hypercholesterolemic rats.

Journal: Atherosclerosis 20040701

Title: Evidence for the involvement of protein kinase C in acidic pH-induced contraction in spontaneously hypertensive rat aorta.

Journal: Pharmacology 20040501

Title: Effect of tyrosine kinase blockade on norepinephrine-induced cytosolic calcium response in rat afferent arterioles.

Journal: American journal of physiology. Renal physiology 20040501

Title: Heat-shock treatment-mediated increase in transduction by recombinant adeno-associated virus 2 vectors is independent of the cellular heat-shock protein 90.

Journal: The Journal of biological chemistry 20040326

Title: Expression of the beacon gene in the rat adrenal gland: direct inhibitory effect of beacon[47-73] on aldosterone secretion from dispersed adrenal zona glomerulosa cells.

Journal: International journal of molecular medicine 20040201

Title: Differential role of PTK and ERK MAPK in superoxide impairment of K(ATP) and K(Ca) channel cerebrovasodilation.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030701

Title: Tyrphostin A23 inhibits internalization of the transferrin receptor by perturbing the interaction between tyrosine motifs and the medium chain subunit of the AP-2 adaptor complex.

Journal: The Journal of biological chemistry 20030404

Title: A novel function for chemokines: downregulation of neutrophil migration.

Journal: Scandinavian journal of immunology 20030401

Title: Monocytic activation of protein tyrosine kinase, protein kinase A and protein kinase C induced by porins isolated from Salmonella enterica serovar Typhimurium.

Journal: The Journal of infection 20030201

Title: Enhancement of glucose transport in rat thymocytes by different radical sources.

Journal: Free radical research 20030201

Title: Cellular signaling during the macrophage invasion by Trypanosoma cruzi.

Journal: Histochemistry and cell biology 20021201

Title: Tyrosine kinases regulate intracellular calcium during alpha(2)-adrenergic contraction in rat aorta.

Journal: American journal of physiology. Heart and circulatory physiology 20021001

Title: Regulation of steroidogenic genes by insulin-like growth factor-1 and follicle-stimulating hormone: differential responses of cytochrome P450 side-chain cleavage, steroidogenic acute regulatory protein, and 3beta-hydroxysteroid dehydrogenase/isomerase in rat granulosa cells.

Journal: Biology of reproduction 20020901

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Acute and chronic effects of genistein, tyrphostin and lavendustin A on steroid synthesis in luteinized human granulosa cells.

Journal: Human reproduction (Oxford, England) 20020301

Title: Activation of background membrane conductance by the tyrosine kinase inhibitor tyrphostin A23 and its inactive analog tyrphostin A1 in guinea pig ventricular myocytes.

Journal: Japanese journal of pharmacology 20011101

Title: Forskolin activation of apical Cl- channel and Na+/K+/2Cl- cotransporter via a PTK-dependent pathway in renal epithelium.

Journal: Biochemical and biophysical research communications 20010727

Title: Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade.

Journal: The Journal of physiology 20010401

Title: Chronic nicotine alters NO signaling of Ca(2+) channels in cerebral arterioles.

Journal: Circulation research 20010216

Title: Tyrosine kinase involvement in renal arteriolar constrictor responses to angiotensin II.

Journal: Hypertension (Dallas, Tex. : 1979) 20010201

Title: Epidermal growth factor activates store-operated calcium channels in human glomerular mesangial cells.

Journal: Journal of the American Society of Nephrology : JASN 20010101

Title: Modulation of noradrenaline-induced microvascular constriction by protein kinase inhibitors.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010101

Title: Secretoneurin, a novel neuropeptide, is a potent chemoattractant for human eosinophils.

Journal: Blood 19980301

Title: Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors.

Journal: Journal of medicinal chemistry 19891001

Title: Du C, et al. Inhibition of CD40 signaling pathway by tyrphostin A1 reduces secretion of IL-12 in macrophage, Th1 cell development and experimental allergic encephalomyelitis in SJL/J mice. J Neuroimmunol. 2001 Mar 1;114(1-2):69-79.

Title: Ogura T, et al. Activation of background membrane conductance by the tyrosine kinase inhibitor tyrphostin A23 and its inactive analog tyrphostin A1 in guinea pig ventricular myocytes. Jpn J Pharmacol. 2001 Nov;87(3):235-9.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:2826-26-8 Molecular Formula|2826-26-8 MDL|2826-26-8 SMILES|2826-26-8 Propanedinitrile,2-[(4-methoxyphenyl)methylene]-