Title: LncRNA SNHG1 promotes α-synuclein aggregation and toxicity by targeting miR-15b-5p to activate SIAH1 in human neuroblastoma SH-SY5Y cells.
Journal: Neurotoxicology 20180901
Title: Paraquat and MPTP induce alteration in the expression profile of long noncoding RNAs in the substantia nigra of mice: Role of the transcription factor Nrf2.
Journal: Toxicology letters 20180701
Title: Protective effects of pituitary adenylate cyclase activating polypeptide against neurotoxic agents.
Journal: Neurotoxicology 20180501
Title: Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
Journal: Neurotoxicology 20170501
Title: Amentoflavone protects dopaminergic neurons in MPTP-induced Parkinson's disease model mice through PI3K/Akt and ERK signaling pathways.
Journal: Toxicology and applied pharmacology 20170315
Title: Nicotine suppresses the neurotoxicity by MPP(+)/MPTP through activating α7nAChR/PI3K/Trx-1 and suppressing ER stress.
Journal: Neurotoxicology 20170301
Title: FosB and ΔFosB expression in brain regions containing differentially susceptible dopamine neurons following acute neurotoxicant exposure.
Journal: Brain research 20161015
Title: Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160901
Title: MPTP neurotoxicity is highly concordant between the sexes among BXD recombinant inbred mouse strains.
Journal: Neurotoxicology 20160701
Title: Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20160608
Title: Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor.
Journal: The Journal of biological chemistry 20160603
Title: Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPARγ agonist in vitro and in MPTP-treated mice.
Journal: Neuroscience 20150827
Title: MPTP's pathway of toxicity indicates central role of transcription factor SP1.
Journal: Archives of toxicology 20150501
Title: Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150201
Title: Decreased expression of organic cation transporters, Oct1 and Oct2, in brain microvessels and its implication to MPTP-induced dopaminergic toxicity in aged mice.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20150101
Title: The role of parkin in the differential susceptibility of tuberoinfundibular and nigrostriatal dopamine neurons to acute toxicant exposure.
Journal: Neurotoxicology 20150101
Title: Neuroprotective effects of ginkgetin against neuroinjury in Parkinson's disease model induced by MPTP via chelating iron.
Journal: Free radical research 20150101
Title: Guanosine exerts neuroprotective effects by reversing mitochondrial dysfunction in a cellular model of Parkinson's disease.
Journal: International journal of molecular medicine 20141101
Title: CNB-001, a novel pyrazole derivative mitigates motor impairments associated with neurodegeneration via suppression of neuroinflammatory and apoptotic response in experimental Parkinson's disease mice.
Journal: Chemico-biological interactions 20140905
Title: Ceftriaxone mediated rescue of nigral oxidative damage and motor deficits in MPTP model of Parkinson's disease in rats.
Journal: Neurotoxicology 20140901
Title: Neuroprotective effect of the chemical chaperone, trehalose in a chronic MPTP-induced Parkinson's disease mouse model.
Journal: Neurotoxicology 20140901
Title: Gene expression regulation of Bcl2, Bax and cytochrome-C by geraniol on chronic MPTP/probenecid induced C57BL/6 mice model of Parkinson's disease.
Journal: Chemico-biological interactions 20140625
Title: Neuroprotective effect of silymarin in a MPTP mouse model of Parkinson's disease.
Journal: Toxicology 20140507
Title: The role of thioredoxin-1 in suppression of endoplasmic reticulum stress in Parkinson disease.
Journal: Free radical biology & medicine 20140201
Title: BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation.
Journal: PloS one 20140101
Title: The c-Abl inhibitor, nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease.
Journal: Scientific reports 20140101
Title: Salvianolic acid B attenuates toxin-induced neuronal damage via Nrf2-dependent glial cells-mediated protective activity in Parkinson's disease models.
Journal: PloS one 20140101
Title: Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism.
Journal: Free radical biology & medicine 20131201
Title: Mangiferin attenuates MPTP induced dopaminergic neurodegeneration and improves motor impairment, redox balance and Bcl-2/Bax expression in experimental Parkinson's disease mice.
Journal: Chemico-biological interactions 20131125
Title: Neuroprotection by tetrahydroxystilbene glucoside in the MPTP mouse model of Parkinson's disease.
Journal: Toxicology letters 20131024
Title: Telmisartan attenuates MPTP induced dopaminergic degeneration and motor dysfunction through regulation of α-synuclein and neurotrophic factors (BDNF and GDNF) expression in C57BL/6J mice.
Journal: Neuropharmacology 20131001
Title: Minocycline, levodopa and MnTMPyP induced changes in the mitochondrial proteome profile of MPTP and maneb and paraquat mice models of Parkinson's disease.
Journal: Biochimica et biophysica acta 20130801
Title: The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.
Journal: The Journal of biological chemistry 20130726
Title: Sustained resistance to acute MPTP toxicity by hypothalamic dopamine neurons following chronic neurotoxicant exposure is associated with sustained up-regulation of parkin protein.
Journal: Neurotoxicology 20130701
Title: Astaxanthin suppresses MPP(+)-induced oxidative damage in PC12 cells through a Sp1/NR1 signaling pathway.
Journal: Marine drugs 20130401
Title: The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
Journal: British journal of pharmacology 20130301
Title: Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin.
Journal: Nature 20130207
Title: Acetylcholinesterase deficiency decreases apoptosis in dopaminergic neurons in the neurotoxin model of Parkinson's disease.
Journal: The international journal of biochemistry & cell biology 20130201
Title: Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease.
Journal: Antioxidants & redox signaling 20130110
Title: Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo.
Journal: Neuro-degenerative diseases 20130101
Title: Biochemical evaluation of the neurotoxicity of MPTP and MPP⁺ in embryonic and newborn mice.
Journal: The Journal of toxicological sciences 20130101
Title: The effect of guggulipid and nimesulide on MPTP-induced mediators of neuroinflammation in rat astrocytoma cells, C6.
Journal: Chemico-biological interactions 20121205
Title: Neuroprotective effects of agmatine in mice infused with a single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Journal: Behavioural brain research 20121201
Title: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neuroblastic apoptosis in the subventricular zone is caused by 1-methy-4-phenylpiridinium (MPP(+)) converted from MPTP through MAO-B.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20121101
Title: Effect of oestrogen receptors on brain NMDA receptors of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.
Journal: Journal of neuroendocrinology 20121101
Title: Transient receptor potential vanilloid subtype 1 contributes to mesencephalic dopaminergic neuronal survival by inhibiting microglia-originated oxidative stress.
Journal: Brain research bulletin 20121101
Title: Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson's disease: role of regulatory T cells.
Journal: Brain, behavior, and immunity 20121101
Title: Loss of parvalbumin-positive neurons from the globus pallidus in animal models of Parkinson disease.
Journal: Journal of neuropathology and experimental neurology 20121101
Title: The soluble isoform of CX3CL1 is necessary for neuroprotection in a mouse model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20121017
Title: Activation of transcription factor MEF2D by bis(3)-cognitin protects dopaminergic neurons and ameliorates Parkinsonian motor defects.
Journal: The Journal of biological chemistry 20121005
Title: Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease.
Journal: The Journal of nutritional biochemistry 20121001
Title: The effects of rehabilitative training on the behaviors of Parkinson's disease mouse and underlying mechanism.
Journal: The International journal of neuroscience 20121001
Title: The nigrostriatal system in the presymptomatic and symptomatic stages in the MPTP monkey model: a PET, histological and biochemical study.
Journal: Neurobiology of disease 20121001
Title: L-DOPA pharmacokinetics in the MPTP-lesioned macaque model of Parkinson's disease.
Journal: Neuropharmacology 20121001
Title: Ogg1 null mice exhibit age-associated loss of the nigrostriatal pathway and increased sensitivity to MPTP.
Journal: Neurochemistry international 20121001
Title: Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease.
Journal: Molecular neurobiology 20121001
Title: Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Journal: Cellular and molecular life sciences : CMLS 20121001
Title: Low nigrostriatal reserve for motor parkinsonism in nonhuman primates.
Journal: Experimental neurology 20121001
Title: Non-human primate FOG develops with advanced parkinsonism induced by MPTP Treatment.
Journal: Experimental neurology 20121001
Title: Sirtuin 2 (SIRT2) enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via deacetylating forkhead box O3a (Foxo3a) and activating Bim protein.
Journal: The Journal of biological chemistry 20120921
Title: Rosiglitazone, a PPAR-γ agonist, protects against striatal dopaminergic neurodegeneration induced by 6-OHDA lesions in the substantia nigra of rats.
Journal: Toxicology letters 20120918
Title: The neuroprotection of hydrogen sulfide against MPTP-induced dopaminergic neuron degeneration involves uncoupling protein 2 rather than ATP-sensitive potassium channels.
Journal: Antioxidants & redox signaling 20120915
Title: A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating Scale.
Journal: Movement disorders : official journal of the Movement Disorder Society 20120915
Title: Molecular mechanism underlying the cerebral effect of Gly-Pro-Glu tripeptide bound to L-dopa in a Parkinson's animal model.
Journal: Amino acids 20120901
Title: Metabotropic glutamate receptors in neurodegeneration/neuroprotection: still a hot topic?
Journal: Neurochemistry international 20120901
Title: Cooperative action of JNK and AKT/mTOR in 1-methyl-4-phenylpyridinium-induced autophagy of neuronal PC12 cells.
Journal: Journal of neuroscience research 20120901
Title: Neuroprotective effect of curcuminoids against inflammation-mediated dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120901
Title: Comparison of the D2 receptor regulation and neurotoxicant susceptibility of nigrostriatal dopamine neurons in wild-type and CB1/CB2 receptor knockout mice.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120901
Title: Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation.
Journal: Journal of neurochemistry 20120901
Title: Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Journal of neurochemistry 20120901
Title: LLDT-67 attenuates MPTP-induced neurotoxicity in mice by up-regulating NGF expression.
Journal: Acta pharmacologica Sinica 20120901
Title: Theaflavin ameliorates behavioral deficits, biochemical indices and monoamine transporters expression against subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of Parkinson's disease.
Journal: Neuroscience 20120830
Title: Disruption of programmed masticatory movements in unilateral MPTP-treated monkeys as a model of jaw movement abnormality in Parkinson's disease.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20120801
Title: Alterations of gene expression of sodium channels in dorsal root ganglion neurons of estrogen receptor knockout (ERKO) mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Journal: Endocrine 20120801
Title: L-745,870 reduces L-DOPA-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 20120801
Title: MPTP modulates hippocampal synaptic transmission and activity-dependent synaptic plasticity via dopamine receptors.
Journal: Journal of neurochemistry 20120801
Title: Neural targets for relieving parkinsonian rigidity and bradykinesia with pallidal deep brain stimulation.
Journal: Journal of neurophysiology 20120715
Title: Long-lasting transcriptional refractoriness triggered by a single exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine.
Journal: Neuroscience 20120712
Title: Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model.
Journal: Neuroscience letters 20120711
Title: Docosahexaenoic acid provides protective mechanism in bilaterally MPTP-lesioned rat model of Parkinson's disease.
Journal: Folia histochemica et cytobiologica 20120704
Title: Blockade of metabotropic glutamate receptors inhibits cognition and neurodegeneration in an MPTP-induced Parkinson's disease rat model.
Journal: Pharmacology, biochemistry, and behavior 20120701
Title: Dopamine pathway loss in nucleus accumbens and ventral tegmental area predicts apathetic behavior in MPTP-lesioned monkeys.
Journal: Experimental neurology 20120701
Title: Loss of spinal motor neurons and alteration of alpha-synuclein immunostaining in MPTP induced Parkinsonism in mice.
Journal: Journal of chemical neuroanatomy 20120701
Title: Neurotoxin-based models of Parkinson's disease.
Journal: Neuroscience 20120601
Title: Blood-borne macrophage-neural cell interactions hitchhike on endosome networks for cell-based nanozyme brain delivery.
Journal: Nanomedicine (London, England) 20120601
Title: Recovery of hypothalamic tuberoinfundibular dopamine neurons from acute toxicant exposure is dependent upon protein synthesis and associated with an increase in parkin and ubiquitin carboxy-terminal hydrolase-L1 expression.
Journal: Neurotoxicology 20120601
Title: Electrophysiological characterization of the polyspecific organic cation transporter plasma membrane monoamine transporter.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120601
Title: Effect of pesticides on the aggregation of mutant huntingtin protein.
Journal: Molecular neurobiology 20120601
Title: Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson's disease.
Journal: Experimental neurology 20120601
Title: Pegylated granulocyte colony-stimulating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease.
Journal: Brain : a journal of neurology 20120601
Title: PEP-1-heat shock protein 27 protects from neuronal damage in cells and in a Parkinson's disease mouse model.
Journal: The FEBS journal 20120601
Title: MPTP-induced model of Parkinson's disease in heat shock protein 70.1 knockout mice.
Journal: Molecular medicine reports 20120601
Title: Animal models of L-DOPA-induced dyskinesia: an update on the current options.
Journal: Neuroscience 20120601
Title: Glutathione S-transferase pi mediates MPTP-induced c-Jun N-terminal kinase activation in the nigrostriatal pathway.
Journal: Molecular neurobiology 20120601
Title: Transduced Tat-DJ-1 protein protects against oxidative stress-induced SH-SY5Y cell death and Parkinson disease in a mouse model.
Journal: Molecules and cells 20120531
Title: Protective effect of extract of Acanthopanax senticosus Harms on dopaminergic neurons in Parkinson's disease mice.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120515
Title: Lithium and oxidative stress lessons from the MPTP model of Parkinson's disease.
Journal: Neuroscience letters 20120510
Title: Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on retinal dopaminergic system in mice.
Journal: Neuroscience letters 20120502
Title: Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease.
Journal: Antioxidants & redox signaling 20120501
Title: Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic, nitric oxidergic, and cholinergic neurotransmitters in myenteric plexus.
Journal: Journal of molecular neuroscience : MN 20120501
Title: Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells.
Journal: Biochimica et biophysica acta 20120501
Title: Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson's disease.
Journal: Behavioural brain research 20120501
Title: Neddylation positively regulates the ubiquitin E3 ligase activity of parkin.
Journal: Journal of neuroscience research 20120501
Title: α7 nicotinic acetylcholine receptor mediated neuroprotection in Parkinson's disease.
Journal: Current drug targets 20120501
Title: Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors.
Journal: Molecular pharmacology 20120501
Title: Investigate the chronic neurotoxic effects of diquat.
Journal: Neurochemical research 20120501
Title: Susceptibility to a parkinsonian toxin varies during primate development.
Journal: Experimental neurology 20120501
Title: Correlation between decreased motor activity and dopaminergic degeneration in the ventrolateral putamen in monkeys receiving repeated MPTP administrations: a positron emission tomography study.
Journal: Neuroscience research 20120501
Title: Differential susceptibility to the PPAR-γ agonist pioglitazone in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 6-hydroxydopamine rodent models of Parkinson's disease.
Journal: Pharmacological research 20120501
Title: Increased α-synuclein phosphorylation and nitration in the aging primate substantia nigra.
Journal: Cell death & disease 20120501
Title: Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.
Journal: Human molecular genetics 20120415
Title: Parkinson's disease: don't mess with calcium.
Journal: The Journal of clinical investigation 20120402
Title: Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling.
Journal: The Journal of clinical investigation 20120402
Title: Molecular imaging of cell death in an experimental model of Parkinson's disease with a novel apoptosis-targeting peptide.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20120401
Title: A novel compound PTIQ protects the nigral dopaminergic neurones in an animal model of Parkinson's disease induced by MPTP.
Journal: British journal of pharmacology 20120401
Title: Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease.
Journal: Cellular and molecular life sciences : CMLS 20120401
Title: Occurrence and distribution of salsolinol-like compound, 1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (ADTIQ) in parkinsonian brains.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20120401
Title: Abnormal metabolic brain networks in a nonhuman primate model of parkinsonism.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120401
Title: Redox modification of Akt mediated by the dopaminergic neurotoxin MPTP, in mouse midbrain, leads to down-regulation of pAkt.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120401
Title: Effects of MK-801 on recognition and neurodegeneration in an MPTP-induced Parkinson's rat model.
Journal: Behavioural brain research 20120401
Title: Animal models of Parkinson's disease.
Journal: The FEBS journal 20120401
Title: Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.
Journal: Behavioural brain research 20120401
Title: Signaling pathways mediating the neuroprotective effects of sex steroids and SERMs in Parkinson's disease.
Journal: Frontiers in neuroendocrinology 20120401
Title: Murine motor and behavior functional evaluations for acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120301
Title: Modeling mitochondrial dysfunctions in the brain: from mice to men.
Journal: Journal of inherited metabolic disease 20120301
Title: Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease.
Journal: Cell death and differentiation 20120301
Title: Increase in endoplasmic reticulum-associated tissue transglutaminase and enzymatic activation in a cellular model of Parkinson's disease.
Journal: Neurobiology of disease 20120301
Title: Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20120301
Title: Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons.
Journal: Human molecular genetics 20120301
Title: Partial dopamine depletion in MPTP-treated mice differentially altered motor skill learning and action control.
Journal: Behavioural brain research 20120301
Title: Harpagoside attenuates MPTP/MPP⁺ induced dopaminergic neurodegeneration and movement disorder via elevating glial cell line-derived neurotrophic factor.
Journal: Journal of neurochemistry 20120301
Title: Social enrichment attenuates nigrostriatal lesioning and reverses motor impairment in a progressive 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.
Journal: Neurobiology of disease 20120301
Title: Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways.
Journal: Neurobiology of disease 20120301
Title: Ablation of serum response factor in dopaminergic neurons exacerbates susceptibility towards MPTP-induced oxidative stress.
Journal: The European journal of neuroscience 20120301
Title: Prevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL.
Journal: Aging 20120301
Title: Modeling Parkinson's disease in primates: The MPTP model.
Journal: Cold Spring Harbor perspectives in medicine 20120301
Title: [Protective effect of nicotinamide in a mouse Parkinson's disease model].
Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20120301
Title: Lipopolysaccharide-induced nigral inflammation leads to increased IL-1β tissue content and expression of astrocytic glial cell line-derived neurotrophic factor.
Journal: Neuroscience letters 20120227
Title: Selective neuroprotective effects of the S18Y polymorphic variant of UCH-L1 in the dopaminergic system.
Journal: Human molecular genetics 20120215
Title: Dangguijakyak-san protects dopamine neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity under postmenopausal conditions.
Journal: Journal of ethnopharmacology 20120215
Title: Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/β-catenin signaling pathways: functional consequences for neuroprotection and repair.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120208
Title: Oral administration of coenzyme Q₁₀ reduces MPTP-induced loss of dopaminergic nerve terminals in the striatum in mice.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120201
Title: Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells.
Journal: Cell research 20120201
Title: Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice.
Journal: Journal of neurochemistry 20120201
Title: The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity.
Journal: PLoS genetics 20120201
Title: Ghrelin protects spinal cord motoneurons against chronic glutamate excitotoxicity by inhibiting microglial activation.
Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20120201
Title: Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.
Journal: Nature medicine 20120129
Title: Theaflavin, a black tea polyphenol, protects nigral dopaminergic neurons against chronic MPTP/probenecid induced Parkinson's disease.
Journal: Brain research 20120118
Title: Bee venom protects SH-SY5Y human neuroblastoma cells from 1-methyl-4-phenylpyridinium-induced apoptotic cell death.
Journal: Brain research 20120106
Title: 5-HT2A receptor levels increase in MPTP-lesioned macaques treated chronically with L-DOPA.
Journal: Neurobiology of aging 20120101
Title: Regulation of cortical and striatal 5-HT1A receptors in the MPTP-lesioned macaque.
Journal: Neurobiology of aging 20120101
Title: Clavulanic acid does not affect convulsions in acute seizure tests in mice.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20120101
Title: Docosahexaenoic acid promotes dopaminergic differentiation in induced pluripotent stem cells and inhibits teratoma formation in rats with Parkinson-like pathology.
Journal: Cell transplantation 20120101
Title: Oestrogen receptors and signalling pathways: implications for neuroprotective effects of sex steroids in Parkinson's disease.
Journal: Journal of neuroendocrinology 20120101
Title: Traditional chinese medicine for senile dementia.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Effect of globus pallidus internus stimulation on neuronal activity in the pedunculopontine tegmental nucleus in the primate model of Parkinson's disease.
Journal: Experimental neurology 20120101
Title: Phytochemical characteristics, free radical scavenging activities, and neuroprotection of five medicinal plant extracts.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: High-fat diet exacerbates MPTP-induced dopaminergic degeneration in mice.
Journal: Neurobiology of disease 20120101
Title: Oxidative stress, mitochondrial dysfunction, and aging.
Journal: Journal of signal transduction 20120101
Title: Asiaticoside: attenuation of neurotoxicity induced by MPTP in a rat model of Parkinsonism via maintaining redox balance and up-regulating the ratio of Bcl-2/Bax.
Journal: Pharmacology, biochemistry, and behavior 20120101
Title: External pallidal stimulation improves parkinsonian motor signs and modulates neuronal activity throughout the basal ganglia thalamic network.
Journal: Experimental neurology 20120101
Title: Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease.
Journal: Neurotoxicity research 20120101
Title: Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia.
Journal: Parkinson's disease 20120101
Title: Adaptive alternative splicing correlates with less environmental risk of parkinsonism.
Journal: Neuro-degenerative diseases 20120101
Title: 4-iodophenyl isothiocyanate: a neuroprotective compound.
Journal: Restorative neurology and neuroscience 20120101
Title: The MPTP neurotoxic lesion model of Parkinson's disease activates the apolipoprotein E cascade in the mouse brain.
Journal: Experimental neurology 20120101
Title: Clinical application of stem cell therapy in Parkinson's disease.
Journal: BMC medicine 20120101
Title: Alpha oscillations in the pedunculopontine nucleus correlate with gait performance in parkinsonism.
Journal: Brain : a journal of neurology 20120101
Title: CART peptide is a potential endogenous antioxidant and preferentially localized in mitochondria.
Journal: PloS one 20120101
Title: Connecting the dots between PubMed abstracts.
Journal: PloS one 20120101
Title: NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration.
Journal: Journal of neuroinflammation 20120101
Title: Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation.
Journal: PloS one 20120101
Title: The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease.
Journal: Parkinson's disease 20120101
Title: Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism.
Journal: Chinese medicine 20120101
Title: Genetic dissection of strain dependent paraquat-induced neurodegeneration in the substantia nigra pars compacta.
Journal: PloS one 20120101
Title: Elevated pontine and putamenal GABA levels in mild-moderate Parkinson disease detected by 7 tesla proton MRS.
Journal: PloS one 20120101
Title: Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema.
Journal: Journal of inflammation (London, England) 20120101
Title: An alteration in the lateral geniculate nucleus of experimental glaucoma monkeys: in vivo positron emission tomography imaging of glial activation.
Journal: PloS one 20120101
Title: Lactulose: an effective preventive and therapeutic option for ischemic stroke by production of hydrogen.
Journal: Medical gas research 20120101
Title: Evaluation of blood-brain barrier transport and CNS drug metabolism in diseased and control brain after intravenous L-DOPA in a unilateral rat model of Parkinson's disease.
Journal: Fluids and barriers of the CNS 20120101
Title: Antiparkinsonian mechanism of electroconvulsive therapy in MPTP-lesioned non-human primates.
Journal: Neuro-degenerative diseases 20120101
Title: Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease.
Journal: Journal of neuroinflammation 20120101
Title: No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease.
Journal: PloS one 20120101
Title: Minocycline markedly reduces acute visceral nociception via inhibiting neuronal ERK phosphorylation.
Journal: Molecular pain 20120101
Title: A 6-hydroxydopamine in vivo model of Parkinson's disease.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Aspects of innate immunity and Parkinson's disease.
Journal: Frontiers in pharmacology 20120101
Title: Effects of L-carnitine against oxidative stress in human hepatocytes: involvement of peroxisome proliferator-activated receptor alpha.
Journal: Journal of biomedical science 20120101
Title: Natural plant products and extracts that reduce immunoexcitotoxicity-associated neurodegeneration and promote repair within the central nervous system.
Journal: Surgical neurology international 20120101
Title: N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity.
Journal: PloS one 20120101
Title: Effect of Quercetin in the 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-Induced Mouse Model of Parkinson's Disease.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Methylphenidate exposure induces dopamine neuron loss and activation of microglia in the basal ganglia of mice.
Journal: PloS one 20120101
Title: Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP(+)/MPTP Models of Parkinson's Disease In Vitro and In Vivo.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Riluzole neuroprotection in a Parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation.
Journal: BMC neuroscience 20120101
Title: Neuroprotective effects of 17β-estradiol rely on estrogen receptor membrane initiated signals.
Journal: Frontiers in physiology 20120101
Title: Genetic Screening of the Mitochondrial Rho GTPases MIRO1 and MIRO2 in Parkinson's Disease.
Journal: The open neurology journal 20120101
Title: Diverse Roles of JNK and MKK Pathways in the Brain.
Journal: Journal of signal transduction 20120101
Title: The ketogenic diet as a treatment paradigm for diverse neurological disorders.
Journal: Frontiers in pharmacology 20120101
Title: MicroRNAs in Neurotoxicity.
Journal: Journal of toxicology 20120101
Title: Classic and new animal models of Parkinson's disease.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra.
Journal: Current gerontology and geriatrics research 20120101
Title: Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys.
Journal: PloS one 20120101
Title: Oxidative stress and microglial cells in Parkinson's disease.
Journal: Mediators of inflammation 20120101
Title: Mesenchymal stem cells augment neurogenesis in the subventricular zone and enhance differentiation of neural precursor cells into dopaminergic neurons in the substantia nigra of a parkinsonian model.
Journal: Cell transplantation 20120101
Title: Hormone replacement therapy and risk for neurodegenerative diseases.
Journal: International journal of Alzheimer's disease 20120101
Title: Genetic rat models of Parkinson's disease.
Journal: Parkinson's disease 20120101
Title: Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies.
Journal: Parkinson's disease 20120101
Title: Role of alpha-synuclein protein levels in mitochondrial morphology and cell survival in cell lines.
Journal: PloS one 20120101
Title: Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease.
Journal: PloS one 20120101
Title: Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease.
Journal: Mediators of inflammation 20120101
Title: Heterogeneous responses to antioxidants in noradrenergic neurons of the Locus coeruleus indicate differing susceptibility to free radical content.
Journal: Oxidative medicine and cellular longevity 20120101
Title: Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis.
Journal: Parkinson's disease 20120101
Title: Preclinical models to investigate retinal ischemia: advances and drawbacks.
Journal: Frontiers in neurology 20120101
Title: Mitochondria: redox metabolism and dysfunction.
Journal: Biochemistry research international 20120101
Title: Urate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinson's disease.
Journal: PloS one 20120101
Title: Role of vitamin d in Parkinson's disease.
Journal: ISRN neurology 20120101
Title: Gene therapy for Parkinson's disease.
Journal: Parkinson's disease 20120101
Title: Genetics and epigenetics of Parkinson's disease.
Journal: TheScientificWorldJournal 20120101
Title: α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation.
Journal: Journal of neuroinflammation 20120101
Title: The Path to microRNA Therapeutics in Psychiatric and Neurodegenerative Disorders.
Journal: Frontiers in genetics 20120101
Title: Current understanding of the glial response to disorders of the aging CNS.
Journal: Frontiers in pharmacology 20120101
Title: Magnolol Protects against MPTP/MPP(+)-Induced Toxicity via Inhibition of Oxidative Stress in In Vivo and In Vitro Models of Parkinson's Disease.
Journal: Parkinson's disease 20120101
Title: Imaging of microglia in patients with neurodegenerative disorders.
Journal: Frontiers in pharmacology 20120101
Title: Modulation of Neuronal Survival Factor MEF2 by Kinases in Parkinson's Disease.
Journal: Frontiers in physiology 20120101
Title: Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases.
Journal: Oxidative medicine and cellular longevity 20120101
Title: Patterns of Cell Activity in the Subthalamic Region Associated with the Neuroprotective Action of Near-Infrared Light Treatment in MPTP-Treated Mice.
Journal: Parkinson's disease 20120101
Title: High frequency deep brain stimulation attenuates subthalamic and cortical rhythms in Parkinson's disease.
Journal: Frontiers in human neuroscience 20120101
Title: Mitochondrial Stress Signalling: HTRA2 and Parkinson's Disease.
Journal: International journal of cell biology 20120101
Title: Mechanism of oxidative stress in neurodegeneration.
Journal: Oxidative medicine and cellular longevity 20120101
Title: The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection.
Journal: Oxidative medicine and cellular longevity 20120101
Title: Matrix metalloproteinases and minocycline: therapeutic avenues for fragile X syndrome.
Journal: Neural plasticity 20120101
Title: Survival of Dopaminergic Amacrine Cells after Near-Infrared Light Treatment in MPTP-Treated Mice.
Journal: ISRN neurology 20120101
Title: Endocannabinoid modulation of dopaminergic motor circuits.
Journal: Frontiers in pharmacology 20120101
Title: Antioxidant protects against increases in low molecular weight hyaluronan and inflammation in asphyxiated newborn pigs resuscitated with 100% oxygen.
Journal: PloS one 20120101
Title: Intensive rehabilitation treatment in parkinsonian patients with dyskinesias: a preliminary study with 6-month followup.
Journal: Parkinson's disease 20120101
Title: Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease.
Journal: PloS one 20120101
Title: Non-stationary discharge patterns in motor cortex under subthalamic nucleus deep brain stimulation.
Journal: Frontiers in integrative neuroscience 20120101
Title: 25-Hydroxyvitamin D depletion does not exacerbate MPTP-induced dopamine neuron damage in mice.
Journal: PloS one 20120101
Title: Overexpression of parkin ameliorates dopaminergic neurodegeneration induced by 1- methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Journal: PloS one 20120101
Title: Behavioral improvement in MPTP-treated nonhuman primates in the HALLWAY task after transfer of TH cDNA to host astrocytes.
Journal: Acta neurobiologiae experimentalis 20120101
Title: Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease.
Journal: PloS one 20120101
Title: Acacetin protects dopaminergic cells against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuroinflammation in vitro and in vivo.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice.
Journal: PloS one 20120101
Title: Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death.
Journal: PloS one 20120101
Title: The monoamine re-uptake inhibitor UWA-101 improves motor fluctuations in the MPTP-lesioned common marmoset.
Journal: PloS one 20120101
Title: Unexpected neuronal protection of SU5416 against 1-Methyl-4-phenylpyridinium ion-induced toxicity via inhibiting neuronal nitric oxide synthase.
Journal: PloS one 20120101
Title: 17α-Ethynyl-androst-5-ene-3β,7β,17β-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease.
Journal: Parkinson's disease 20120101
Title: PET analysis of dopaminergic neurodegeneration in relation to immobility in the MPTP-treated common marmoset, a model for Parkinson's disease.
Journal: PloS one 20120101
Title: Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson's disease.
Journal: Journal of neuroinflammation 20120101
Title: Time-dependent slowly-reversible inhibition of monoamine oxidase A by N-substituted 1,2,3,6-tetrahydropyridines.
Journal: Bioorganic & medicinal chemistry 20111215
Title: Cannabinoid receptor type 1 protects nigrostriatal dopaminergic neurons against MPTP neurotoxicity by inhibiting microglial activation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20111215
Title: Sex- and brain region-specific role of cytochrome c oxidase in 1-methyl-4-phenylpyridinium-mediated astrocyte vulnerability.
Journal: Journal of neuroscience research 20111201
Title: Antidepressant-like properties of sarizotan in experimental Parkinsonism.
Journal: Psychopharmacology 20111201
Title: Novel variant Pro143Ala in HTRA2 contributes to Parkinson's disease by inducing hyperphosphorylation of HTRA2 protein in mitochondria.
Journal: Human genetics 20111201
Title: SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease.
Journal: Neuropharmacology 20111201
Title: Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β.
Journal: The FEBS journal 20111201
Title: Environmental- and injury-related epidemic-assistance investigations, 1946-2005.
Journal: American journal of epidemiology 20111201
Title: Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption.
Journal: Translational psychiatry 20111201
Title: Prospect of cell therapy for Parkinson's disease.
Journal: Anatomy & cell biology 20111201
Title: The use of Stronger Neo-Minophagen C, a glycyrrhizin-containing preparation, in robust neuroprotection in the postischemic brain.
Journal: Anatomy & cell biology 20111201
Title: Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease.
Journal: Toxicology letters 20111130
Title: Preventive and therapeutic effects of caffeic acid against inflammatory injury in striatum of MPTP-treated mice.
Journal: European journal of pharmacology 20111130
Title: Chronic progesterone treatment of male rats with unilateral 6-hydroxydopamine lesion of the dorsal striatum exacerbates [corrected] parkinsonian symptoms.
Journal: Neuroscience 20111124
Title: Impact of exercise on mitochondrial transcription factor expression and damage in the striatum of a chronic mouse model of Parkinson's disease.
Journal: Neuroscience letters 20111121
Title: Dopamine-depletion and increased α-synuclein load induce degeneration of cortical cholinergic fibers in mice.
Journal: Journal of the neurological sciences 20111115
Title: Chronic systemic treatment with a high-dose proteasome inhibitor in mice produces akinesia unrelated to nigrostriatal degeneration.
Journal: Neurobiology of aging 20111101
Title: Contamination of mesenchymal stem-cells with fibroblasts accelerates neurodegeneration in an experimental model of Parkinson's disease.
Journal: Stem cell reviews 20111101
Title: Pallidothalamic-projecting neurons in Macaca fascicularis co-express GABAergic and glutamatergic markers as seen in control, MPTP-treated and dyskinetic monkeys.
Journal: Brain structure & function 20111101
Title: Association analysis of PARP1 polymorphisms with Parkinson's disease.
Journal: Parkinsonism & related disorders 20111101
Title: Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum.
Journal: The European journal of neuroscience 20111101
Title: Subthalamo-pallidal interactions underlying parkinsonian neuronal oscillations in the primate basal ganglia.
Journal: The European journal of neuroscience 20111101
Title: Natural toxins implicated in the development of Parkinson's disease.
Journal: Therapeutic advances in neurological disorders 20111101
Title: Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Journal: Neuroscience 20111027
Title: L-Dihydroxyphenylalanine modulates the steady-state expression of mouse striatal tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine and its metabolites in an MPTP mouse model of Parkinson's disease.
Journal: Life sciences 20111024
Title: Closed-loop deep brain stimulation is superior in ameliorating parkinsonism.
Journal: Neuron 20111020
Title: Heat shock protein 70 kDa over-expression and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigrostriatal degeneration in mice.
Journal: Neuroscience 20111013
Title: S-Allylcysteine, a garlic compound, protects against oxidative stress in 1-methyl-4-phenylpyridinium-induced parkinsonism in mice.
Journal: The Journal of nutritional biochemistry 20111001
Title: The effect of docosahexaenoic Acid on visual evoked potentials in a mouse model of Parkinson's disease: the role of cyclooxygenase-2 and nuclear factor kappa-B.
Journal: Neurotoxicity research 20111001
Title: JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro.
Journal: Journal of molecular neuroscience : MN 20111001
Title: Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease.
Journal: British journal of pharmacology 20111001
Title: The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice.
Journal: Neurochemical research 20111001
Title: Neuroprotection effects of retained acupuncture in neurotoxin-induced Parkinson's disease mice.
Journal: Brain, behavior, and immunity 20111001
Title: The influence and the mechanism of docosahexaenoic acid on a mouse model of Parkinson's disease.
Journal: Neurochemistry international 20111001
Title: Regulation of myocyte enhancer factor-2 transcription factors by neurotoxins.
Journal: Neurotoxicology 20111001
Title: Melatonin protects against neurobehavioral and mitochondrial deficits in a chronic mouse model of Parkinson's disease.
Journal: Pharmacology, biochemistry, and behavior 20111001
Title: Profiling changes in gait dynamics resulting from progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigrostriatal lesioning.
Journal: Journal of neuroscience research 20111001
Title: Phosphatidylinositol 3-kinase/Akt signaling pathway mediates acupuncture-induced dopaminergic neuron protection and motor function improvement in a mouse model of Parkinson's disease.
Journal: The International journal of neuroscience 20111001
Title: Regulation of bat echolocation pulse acoustics by striatal dopamine.
Journal: The Journal of experimental biology 20111001
Title: Antiparkinsonian properties of a nerve growth factor dipeptide mimetic GK-2 in in vivo experiments.
Journal: Bulletin of experimental biology and medicine 20111001
Title: Midbrain dopamine neurons associated with reward processing innervate the neurogenic subventricular zone.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110914
Title: Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults.
Journal: Nature neuroscience 20110904
Title: Mice lacking major brain gangliosides develop parkinsonism.
Journal: Neurochemical research 20110901
Title: Cell-mediated transfer of catalase nanoparticles from macrophages to brain endothelial, glial and neuronal cells.
Journal: Nanomedicine (London, England) 20110901
Title: Estrogen receptors and gonadal steroids in vulnerability and protection of dopamine neurons in a mouse model of Parkinson's disease.
Journal: Neuropharmacology 20110901
Title: Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110901
Title: Aged monkeys as a partial model for Parkinson's disease.
Journal: Pharmacology, biochemistry, and behavior 20110901
Title: Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase.
Journal: Disease models & mechanisms 20110901
Title: An angiogenic inhibitor, cyclic RGDfV, attenuates MPTP-induced dopamine neuron toxicity.
Journal: Experimental neurology 20110901
Title: Differential DAergic Control of D1 and D2 Receptor Agonist Over Locomotor Activity and GABA Level in the Striatum.
Journal: Experimental neurobiology 20110901
Title: Involvement of the Fc gamma receptor in a chronic N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of dopaminergic loss.
Journal: The Journal of biological chemistry 20110819
Title: Probing the steric space at the floor of the D1 dopamine receptor orthosteric binding domain: 7α-, 7β-, 8α-, and 8β-methyl substituted dihydrexidine analogues.
Journal: Journal of medicinal chemistry 20110811
Title: The effect of nNOS inhibitors on toxin-induced cell death in dopaminergic cell lines depends on the extent of enzyme expression.
Journal: Brain research 20110802
Title: Constitutive Ret signaling is protective for dopaminergic cell bodies but not for axonal terminals.
Journal: Neurobiology of aging 20110801
Title: Both stereoselective (R)- and (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline enantiomers protect striatal terminals against rotenone-induced suppression of dopamine release.
Journal: Neurotoxicity research 20110801
Title: The critical role of the MyD88-dependent pathway in non-CNS MPTP-mediated toxicity.
Journal: Brain, behavior, and immunity 20110801
Title: The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease.
Journal: Neurobiology of disease 20110801
Title: Assessment of fetal brain uptake of paraquat in utero using in vivo PET/CT imaging.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110801
Title: Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801
Title: Parkinson's disease mouse models in translational research.
Journal: Mammalian genome : official journal of the International Mammalian Genome Society 20110801
Title: Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity.
Journal: Environmental health perspectives 20110801
Title: MPTP-meditated hippocampal dopamine deprivation modulates synaptic transmission and activity-dependent synaptic plasticity.
Journal: Toxicology and applied pharmacology 20110801
Title: MPP(+)-induced toxicity in the presence of dopamine is mediated by COX-2 through oxidative stress.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110801
Title: Endogenous morphine-like compound immunoreactivity increases in parkinsonism.
Journal: Brain : a journal of neurology 20110801
Title: Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease.
Journal: Journal of neuropathology and experimental neurology 20110801
Title: REM sleep behavior disorder in the marmoset MPTP model of early Parkinson disease.
Journal: Sleep 20110801
Title: Transcriptional modulation by VIP: a rational target against inflammatory disease.
Journal: Clinical epigenetics 20110801
Title: Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.
Journal: Journal of medicinal chemistry 20110728
Title: Bioactive neo-clerodane diterpenoids from the whole plants of Ajuga ciliata Bunge.
Journal: Journal of natural products 20110722
Title: Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a mouse model of Parkinson's disease.
Journal: Antioxidants & redox signaling 20110715
Title: Changes of gene expression profiles in the cervical spinal cord by acupuncture in an MPTP-intoxicated mouse model: microarray analysis.
Journal: Gene 20110715
Title: Ethyl pyruvate rescues nigrostriatal dopaminergic neurons by regulating glial activation in a mouse model of Parkinson's disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110715
Title: Identification of N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile.
Journal: Journal of medicinal chemistry 20110714
Title: Metabotropic glutamate receptor type 5 in levodopa-induced motor complications.
Journal: Neurobiology of aging 20110701
Title: Chronic dietary supplementation with turmeric protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-mediated neurotoxicity in vivo: implications for Parkinson's disease.
Journal: The British journal of nutrition 20110701
Title: Upregulation of microglial C1q expression has no effects on nigrostriatal dopaminergic injury in the MPTP mouse model of Parkinson disease.
Journal: Journal of neuroimmunology 20110701
Title: Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys.
Journal: Brain : a journal of neurology 20110701
Title: Parkin' control: regulation of PGC-1α through PARIS in Parkinson's disease.
Journal: Disease models & mechanisms 20110701
Title: Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.
Journal: Current pharmaceutical design 20110701
Title: Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity.
Journal: International journal of environmental research and public health 20110701
Title: Pharmacological targeting of the transcription factor Nrf2 at the basal ganglia provides disease modifying therapy for experimental parkinsonism.
Journal: Antioxidants & redox signaling 20110615
Title: Highly potent activity of (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in animal models of Parkinson's disease.
Journal: Journal of medicinal chemistry 20110609
Title: Role of the dopamine transporter in mediating the neuroleptic-induced reduction of tyrosine hydroxylase-immunoreactive midbrain neurons.
Journal: Brain research 20110607
Title: Imidazolium salt (DBZIM) reduces gliosis in mice treated with neurotoxicant 2'-CH(3) -MPTP.
Journal: CNS neuroscience & therapeutics 20110601
Title: DJ-1 cleavage by matrix metalloproteinase 3 mediates oxidative stress-induced dopaminergic cell death.
Journal: Antioxidants & redox signaling 20110601
Title: Primary motor cortex of the parkinsonian monkey: differential effects on the spontaneous activity of pyramidal tract-type neurons.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20110601
Title: Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.
Journal: Environmental health perspectives 20110601
Title: Novel role of aquaporin-4 in CD4+ CD25+ T regulatory cell development and severity of Parkinson's disease.
Journal: Aging cell 20110601
Title: Effects of D-cycloserine on MPTP-induced behavioral and neurological changes: potential for treatment of Parkinson's disease dementia.
Journal: Behavioural brain research 20110601
Title: Rotenone, paraquat, and Parkinson's disease.
Journal: Environmental health perspectives 20110601
Title: The selective mu-opioid receptor antagonist ADL5510 reduces levodopa-induced dyskinesia without affecting antiparkinsonian action in MPTP-lesioned macaque model of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20110601
Title: Harnessing neuroplasticity for clinical applications.
Journal: Brain : a journal of neurology 20110601
Title: Cold water stress attenuates dopaminergic neurotoxicity induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Journal: Acta biochimica et biophysica Sinica 20110601
Title: Long-term potentiation and long-term depression: a clinical perspective.
Journal: Clinics (Sao Paulo, Brazil) 20110601
Title: Epigallocatechin-3-gallate Regulates Inducible Nitric Oxide Synthase Expression in Human Umbilical Vein Endothelial Cells.
Journal: Laboratory animal research 20110601
Title: The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders.
Journal: Experimental neurobiology 20110601
Title: Medical management of Parkinson's disease: focus on neuroprotection.
Journal: Current neuropharmacology 20110601
Title: Kainic Acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines.
Journal: Current neuropharmacology 20110601
Title: Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
Journal: Brain research bulletin 20110530
Title: Effect of intermittent washout periods on progressive lesioning of the nigrostriatal pathway with 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Journal: Neuroscience 20110519
Title: Modeling of presymptomatic and symptomatic stages of parkinsonism in mice.
Journal: Neuroscience 20110505
Title: Dynamic alterations of gene expression of nicotinic acetylcholine receptor α7, α4 and β2 subunits in an acute MPTP-lesioned mouse model.
Journal: Neuroscience letters 20110502
Title: Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson's disease.
Journal: European journal of neurology 20110501
Title: Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation.
Journal: Neuropharmacology 20110501
Title: The acute antiparkinsonian and antidyskinetic effect of AFQ056, a novel metabotropic glutamate receptor type 5 antagonist, in L-Dopa-treated parkinsonian monkeys.
Journal: Parkinsonism & related disorders 20110501
Title: Modulation of α-synuclein aggregation by dopamine in the presence of MPTP and its metabolite.
Journal: The FEBS journal 20110501
Title: The herbal preparation Padma® 28 protects against neurotoxicity in PC12 cells.
Journal: Phytotherapy research : PTR 20110501
Title: Neuroprotective effects of creatine.
Journal: Amino acids 20110501
Title: Brain 5-HT(2A) receptors in MPTP monkeys and levodopa-induced dyskinesias.
Journal: The European journal of neuroscience 20110501
Title: Knockdown of cytosolic NADP(+) -dependent isocitrate dehydrogenase enhances MPP(+) -induced oxidative injury in PC12 cells.
Journal: BMB reports 20110501
Title: A tale on animal models of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20110501
Title: Phenylbutyrate up-regulates the DJ-1 protein and protects neurons in cell culture and in animal models of Parkinson disease.
Journal: The Journal of biological chemistry 20110429
Title: BL-1023 improves behavior and neuronal survival in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice.
Journal: Neuroscience 20110428
Title: Dopaminergic and behavioral correlates of progressive lesioning of the nigrostriatal pathway with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Neuroscience 20110428
Title: Possible role of propofol's cyclooxygenase-inhibiting property in alleviating dopaminergic neuronal loss in the substantia nigra in an MPTP-induced murine model of Parkinson's disease.
Journal: Brain research 20110428
Title: Effects of treadmill exercise on behavioral recovery and neural changes in the substantia nigra and striatum of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse.
Journal: Brain research 20110422
Title: Zonisamide-induced long-lasting recovery of dopaminergic neurons from MPTP-toxicity.
Journal: Brain research 20110412
Title: Endometrial stem cell transplantation restores dopamine production in a Parkinson's disease model.
Journal: Journal of cellular and molecular medicine 20110401
Title: Metabolic manipulators: a well founded strategy to combat mitochondrial dysfunction.
Journal: Journal of inherited metabolic disease 20110401
Title: Dissociation of motor symptoms during deep brain stimulation of the subthalamic nucleus in the region of the internal capsule.
Journal: Experimental neurology 20110401
Title: Neuroprotective changes of striatal degeneration-related gene expression by acupuncture in an MPTP mouse model of Parkinsonism: microarray analysis.
Journal: Cellular and molecular neurobiology 20110401
Title: Mutant α-synuclein and aging reduce neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal: Aging cell 20110401
Title: Mitochondrial quality control and Parkinson's disease: a pathway unfolds.
Journal: Molecular neurobiology 20110401
Title: Baicalein protects the brain against neuron impairments induced by MPTP in C57BL/6 mice.
Journal: Pharmacology, biochemistry, and behavior 20110401
Title: Bee venom reduces neuroinflammation in the MPTP-induced model of Parkinson's disease.
Journal: The International journal of neuroscience 20110401
Title: Differential structural plasticity of corticostriatal and thalamostriatal axo-spinous synapses in MPTP-treated Parkinsonian monkeys.
Journal: The Journal of comparative neurology 20110401
Title: Alterations in the mitochondrial proteome of neuroblastoma cells in response to complex 1 inhibition.
Journal: Journal of proteome research 20110401
Title: The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects.
Journal: Current topics in medicinal chemistry 20110401
Title: IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson's disease.
Journal: Cell death & disease 20110401
Title: Polygalae radix inhibits toxin-induced neuronal death in the Parkinson's disease models.
Journal: Journal of ethnopharmacology 20110324
Title: The endoplasmic reticulum stress sensor, ATF6α, protects against neurotoxin-induced dopaminergic neuronal death.
Journal: The Journal of biological chemistry 20110311
Title: New evidences for fractalkine/CX3CL1 involved in substantia nigral microglial activation and behavioral changes in a rat model of Parkinson's disease.
Journal: Neurobiology of aging 20110301
Title: Neuroprotective and anti-inflammatory effects of the adenosine A(2A) receptor antagonist ST1535 in a MPTP mouse model of Parkinson's disease.
Journal: Synapse (New York, N.Y.) 20110301
Title: Running wheel activity restores MPTP-induced functional deficits.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20110301
Title: Estradiol modulation of cortical, striatal and raphe nucleus 5-HT1A and 5-HT2A receptors of female hemiparkinsonian monkeys after long-term ovariectomy.
Journal: Neuropharmacology 20110301
Title: Different sub-cellular localization of alpha-synuclein in the C57BL\6J mouse's central nervous system by two novel monoclonal antibodies.
Journal: Journal of chemical neuroanatomy 20110301
Title: Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration.
Journal: Experimental neurology 20110301
Title: Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neurons.
Journal: Journal of neuroscience research 20110301
Title: Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted mice.
Journal: Aging 20110301
Title: Experimental modeling of preclinical and clinical stages of Parkinson's disease.
Journal: Bulletin of experimental biology and medicine 20110301
Title: In vitro study of neuroprotective properties of GK-2, a new original nerve growth factor mimetic.
Journal: Bulletin of experimental biology and medicine 20110301
Title: Enhanced GDNF expression in dopaminergic cells of monkeys grafted with carotid body cell aggregates.
Journal: Brain research 20110223
Title: Parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and alpha-synuclein mutations promote Tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in vitro.
Journal: The Journal of biological chemistry 20110218
Title: α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209
Title: Minor retinal degeneration in Parkinson's disease.
Journal: Medical hypotheses 20110201
Title: Fatty acid amide hydrolase (FAAH) inhibition reduces L-3,4-dihydroxyphenylalanine-induced hyperactivity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned non-human primate model of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 20110201
Title: Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal: Neurobiology of disease 20110201
Title: A neuroprotective role for angiogenin in models of Parkinson's disease.
Journal: Journal of neurochemistry 20110201
Title: Transgenic conversion of omega-6 into omega-3 fatty acids in a mouse model of Parkinson's disease.
Journal: Journal of lipid research 20110201
Title: Protective effect of panaxatriol saponins extracted from Panax notoginseng against MPTP-induced neurotoxicity in vivo.
Journal: Journal of ethnopharmacology 20110127
Title: Enriched environment promotes similar neuronal and behavioral recovery in a young and aged mouse model of Parkinson's disease.
Journal: Neuroscience 20110113
Title: Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110112
Title: Granulocyte-colony stimulating factor (G-CSF) enhances recovery in mouse model of Parkinson's disease.
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Title: Implication of the c-Jun-NH2-terminal kinase pathway in the neuroprotective effect of puerarin against 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in PC-12 cells.
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Title: San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Ganoderma lucidum Protects Dopaminergic Neuron Degeneration through Inhibition of Microglial Activation.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: The Role of Th17 in Neuroimmune Disorders: A Target for CAM Therapy. Part III.
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Title: Acute but not chronic administration of pioglitazone promoted behavioral and neurochemical protective effects in the MPTP model of Parkinson's disease.
Journal: Behavioural brain research 20110101
Title: Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin.
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Title: Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms.
Journal: Environmental health perspectives 20110101
Title: MPTP-induced neuroinflammation increases the expression of pro-inflammatory cytokines and their receptors in mouse brain.
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Title: Antiparkinsonian effects of aqueous methanolic extract of Hyoscyamus niger seeds result from its monoamine oxidase inhibitory and hydroxyl radical scavenging potency.
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Title: Assessment of metabolic changes in the striatum of a MPTP-intoxicated canine model: in vivo ¹H-MRS study of an animal model for Parkinson's disease.
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Title: Astaxanthin protects against MPTP/MPP+-induced mitochondrial dysfunction and ROS production in vivo and in vitro.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110101
Title: Dyskinesias do not develop after chronic intermittent levodopa therapy in clinically hemiparkinsonian rhesus monkeys.
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Title: Kainic acid-induced neurodegenerative model: potentials and limitations.
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Title: Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model.
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Title: Manganese inhalation as a Parkinson disease model.
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Title: Limitations of animal models of Parkinson's disease.
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Title: Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity.
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Title: Inflammatory mechanisms of neurodegeneration in toxin-based models of Parkinson's disease.
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Title: Toxin-induced and genetic animal models of Parkinson's disease.
Journal: Parkinson's disease 20110101
Title: Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection.
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Title: Enhanced glutamate, IP3 and cAMP activity in the cerebral cortex of unilateral 6-hydroxydopamine induced Parkinson's rats: effect of 5-HT, GABA and bone marrow cell supplementation.
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Title: Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice.
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Title: Use of non-steroidal anti-inflammatory drugs and risk of Parkinson's disease: nested case-control study.
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Title: CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease.
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Title: Dispersed activity during passive movement in the globus pallidus of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated primate.
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Title: BCG vaccine-induced neuroprotection in a mouse model of Parkinson's disease.
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Title: Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation.
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Title: Toxicity of neurons treated with herbicides and neuroprotection by mitochondria-targeted antioxidant SS31.
Journal: International journal of environmental research and public health 20110101
Title: Mitochondrial Dysfunction: The Road to Alpha-Synuclein Oligomerization in PD.
Journal: Parkinson's disease 20110101
Title: The endotoxin-induced neuroinflammation model of Parkinson's disease.
Journal: Parkinson's disease 20110101
Title: The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.
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Title: Evolution of extra-nigral damage predicts behavioural deficits in a rat proteasome inhibitor model of Parkinson's disease.
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Title: The intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a new rodent model to test palliative and neuroprotective agents for Parkinson's disease.
Journal: Current pharmaceutical design 20110101
Title: Phosphodiesterase 7 inhibition preserves dopaminergic neurons in cellular and rodent models of Parkinson disease.
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Title: The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease.
Journal: Parkinson's disease 20110101
Title: Hsp70 and its molecular role in nervous system diseases.
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Title: Manganese-Induced Parkinsonism due to Ephedrone Abuse.
Journal: Parkinson's disease 20110101
Title: Mitochondrial fusion/fission, transport and autophagy in Parkinson's disease: when mitochondria get nasty.
Journal: Parkinson's disease 20110101
Title: Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.
Journal: Genome biology 20110101
Title: Efficacy, safety, and patient preference of monoamine oxidase B inhibitors in the treatment of Parkinson's disease.
Journal: Patient preference and adherence 20110101
Title: Dopamine signaling in dorsal versus ventral striatum: the dynamic role of cholinergic interneurons.
Journal: Frontiers in systems neuroscience 20110101
Title: BmDJ-1 is a key regulator of oxidative modification in the development of the silkworm, Bombyx mori.
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Title: Mitochondrial dysfunction in Parkinson's disease.
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Journal: Eksperimental'naia i klinicheskaia farmakologiia 20110101
Title: Drosophila models of Parkinson's disease: discovering relevant pathways and novel therapeutic strategies.
Journal: Parkinson's disease 20110101
Title: Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease.
Journal: Molecular neurodegeneration 20110101
Title: Dynamic stereotypic responses of Basal Ganglia neurons to subthalamic nucleus high-frequency stimulation in the parkinsonian primate.
Journal: Frontiers in systems neuroscience 20110101
Title: Minocycline fails to modulate cerebrospinal fluid HIV infection or immune activation in chronic untreated HIV-1 infection: results of a pilot study.
Journal: AIDS research and therapy 20110101
Title: Balancing the brain: resting state networks and deep brain stimulation.
Journal: Frontiers in integrative neuroscience 20110101
Title: Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation.
Journal: Molecular neurodegeneration 20110101
Title: Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease.
Journal: BMC medical genetics 20110101
Title: Lipopolysaccharide animal models for Parkinson's disease.
Journal: Parkinson's disease 20110101
Title: Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: possible implication in Parkinson's disease incidence.
Journal: Parkinson's disease 20110101
Title: Optimizing a rodent model of Parkinson's disease for exploring the effects and mechanisms of deep brain stimulation.
Journal: Parkinson's disease 20110101
Title: Do somatic mitochondrial DNA mutations contribute to Parkinson's disease?
Journal: Parkinson's disease 20110101
Title: Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy?
Journal: Parkinson's disease 20110101
Title: Dopaminergic Balance between Reward Maximization and Policy Complexity.
Journal: Frontiers in systems neuroscience 20110101
Title: Transcriptional Factor NF-κB as a Target for Therapy in Parkinson's Disease.
Journal: Parkinson's disease 20110101
Title: Available and emerging treatments for Parkinson's disease: a review.
Journal: Drug design, development and therapy 20110101
Title: Dexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia.
Journal: BMC neuroscience 20110101
Title: The antioxidative effect of electro-acupuncture in a mouse model of Parkinson's disease.
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Title: Transplantation of neuronal-primed human bone marrow mesenchymal stem cells in hemiparkinsonian rodents.
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Title: GSK-3 in Neurodegenerative Diseases.
Journal: International journal of Alzheimer's disease 20110101
Title: Melatonin in mitochondrial dysfunction and related disorders.
Journal: International journal of Alzheimer's disease 20110101
Title: Noradrenaline and Parkinson's disease.
Journal: Frontiers in systems neuroscience 20110101
Title: Chronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751)(SL) mice.
Journal: PloS one 20110101
Title: Assessing causal relationships in genomics: From Bradford-Hill criteria to complex gene-environment interactions and directed acyclic graphs.
Journal: Emerging themes in epidemiology 20110101
Title: Neuroprotective effects of marine algae.
Journal: Marine drugs 20110101
Title: Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease.
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Title: Therapeutic effects of hydrogen in animal models of Parkinson's disease.
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Title: The involvement of neuroinflammation and kynurenine pathway in Parkinson's disease.
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Title: The degenerating substantia nigra as a susceptible region for gene transfer-mediated inflammation.
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Title: Loss of specificity in Basal Ganglia related movement disorders.
Journal: Frontiers in systems neuroscience 20110101
Title: Protein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degeneration.
Journal: Molecular neurodegeneration 20110101
Title: Nitric Oxide Synthase Inhibitor Improves De Novo and Long-Term l-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats.
Journal: Frontiers in systems neuroscience 20110101
Title: Distribution of tyrosine hydroxylase-expressing interneurons with respect to anatomical organization of the neostriatum.
Journal: Frontiers in systems neuroscience 20110101
Title: The 5-HT(2A) Receptor Antagonist M100907 Produces Antiparkinsonian Effects and Decreases Striatal Glutamate.
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Title: Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease.
Journal: Alzheimer's research & therapy 20110101
Title: Effect of endurance exercise training on the expression of GFAP, S100B, and NSE in the striatum of chronic/progressive mouse model of Parkinson's disease.
Journal: NeuroRehabilitation 20110101
Title: Neuropharmacological approach against MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine)-induced mouse model of Parkinson's disease.
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Title: Chaotic desynchronization as the therapeutic mechanism of deep brain stimulation.
Journal: Frontiers in systems neuroscience 20110101
Title: α-Synuclein Alters Toll-Like Receptor Expression.
Journal: Frontiers in neuroscience 20110101
Title: Neighboring Pallidal Neurons Do Not Exhibit more Synchronous Oscillations than Remote Ones in the MPTP Primate Model of Parkinson's Disease.
Journal: Frontiers in systems neuroscience 20110101
Title: A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection.
Journal: Molecular neurodegeneration 20110101
Title: Bridging molecular genetics and biomarkers in lewy body and related disorders.
Journal: International journal of Alzheimer's disease 20110101
Title: MPTP Neurotoxicity and Testosterone Induce Dendritic Remodeling of Striatal Medium Spiny Neurons in the C57Bl/6 Mouse.
Journal: Parkinson's disease 20110101
Title: Pharmacological and physiological characterization of the tremulous jaw movement model of parkinsonian tremor: potential insights into the pathophysiology of tremor.
Journal: Frontiers in systems neuroscience 20110101
Title: Estrogens regulate neuroinflammatory genes via estrogen receptors α and β in the frontal cortex of middle-aged female rats.
Journal: Journal of neuroinflammation 20110101
Title: 24-Epibrassinolide, a Phytosterol from the Brassinosteroid Family, Protects Dopaminergic Cells against MPP-Induced Oxidative Stress and Apoptosis.
Journal: Journal of toxicology 20110101
Title: Protective Action of Neurotrophic Factors and Estrogen against Oxidative Stress-Mediated Neurodegeneration.
Journal: Journal of toxicology 20110101
Title: Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism.
Journal: Molecular neurodegeneration 20110101
Title: Enhanced catecholamine transporter binding in the locus coeruleus of patients with early Parkinson disease.
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Title: Oxidative toxicity in neurodegenerative diseases: role of mitochondrial dysfunction and therapeutic strategies.
Journal: Journal of toxicology 20110101
Title: 14-3-3theta protects against neurotoxicity in a cellular Parkinson's disease model through inhibition of the apoptotic factor Bax.
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Title: Neuroprotective effect of kaempferol against a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Past, present, and future of the pathophysiological model of the Basal Ganglia.
Journal: Frontiers in neuroanatomy 20110101
Title: [Influence of hemantane and doxycycline on MPTP-evoked behavior violations in C57BL/6 mice].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20110101
Title: The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys.
Journal: Journal of neuroinflammation 20110101
Title: Renin angiotensin system and gender differences in dopaminergic degeneration.
Journal: Molecular neurodegeneration 20110101
Title: Localization and Function of GABA Transporters GAT-1 and GAT-3 in the Basal Ganglia.
Journal: Frontiers in systems neuroscience 20110101
Title: Degenerate wave and capacitive coupling increase human MSC invasion and proliferation while reducing cytotoxicity in an in vitro wound healing model.
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Title: Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unifying hypothesis.
Journal: Surgical neurology international 20110101
Title: Early presymptomatic and long-term changes of rest activity cycles and cognitive behavior in a MPTP-monkey model of Parkinson's disease.
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Title: Bladder, bowel, and sexual dysfunction in Parkinson's disease.
Journal: Parkinson's disease 20110101
Title: Peripheral neuropathy in the Twitcher mouse involves the activation of axonal caspase 3.
Journal: ASN neuro 20110101
Title: D-β-hydroxybutyrate is protective in mouse models of Huntington's disease.
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Title: The locus coeruleus is directly implicated in L-DOPA-induced dyskinesia in parkinsonian rats: an electrophysiological and behavioural study.
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Title: Controversies in neurology: why monoamine oxidase B inhibitors could be a good choice for the initial treatment of Parkinson's disease.
Journal: BMC neurology 20110101
Title: Regulation by glycogen synthase kinase-3 of inflammation and T cells in CNS diseases.
Journal: Frontiers in molecular neuroscience 20110101
Title: Multi-neuronal recordings in the Basal Ganglia in normal and dystonic rats.
Journal: Frontiers in systems neuroscience 20110101
Title: New aspects of mitochondrial Uncoupling Proteins (UCPs) and their roles in tumorigenesis.
Journal: International journal of molecular sciences 20110101
Title: Type A monoamine oxidase regulates life and death of neurons in neurodegeneration and neuroprotection.
Journal: International review of neurobiology 20110101
Title: Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade.
Journal: Journal of neuroinflammation 20110101
Title: The role of manganese superoxide dismutase in inflammation defense.
Journal: Enzyme research 20110101
Title: The role of the MYD88-dependent pathway in MPTP-induced brain dopaminergic degeneration.
Journal: Journal of neuroinflammation 20110101
Title: Protective effect of tetrahydroxystilbene glucoside on 6-OHDA-induced apoptosis in PC12 cells through the ROS-NO pathway.
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Title: Low concentrations of methamphetamine can protect dopaminergic cells against a larger oxidative stress injury: mechanistic study.
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Title: The role of inhibition in generating and controlling Parkinson's disease oscillations in the Basal Ganglia.
Journal: Frontiers in systems neuroscience 20110101
Title: L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission.
Journal: Frontiers in behavioral neuroscience 20110101
Title: Early exposure to paraquat sensitizes dopaminergic neurons to subsequent silencing of PINK1 gene expression in mice.
Journal: International journal of biological sciences 20110101
Title: Dissociation of progressive dopaminergic neuronal death and behavioral impairments by Bax deletion in a mouse model of Parkinson's diseases.
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Title: Stuck at the bench: Potential natural neuroprotective compounds for concussion.
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Title: Beyond cAMP: The Regulation of Akt and GSK3 by Dopamine Receptors.
Journal: Frontiers in molecular neuroscience 20110101
Title: Roles of oxidative stress, apoptosis, PGC-1α and mitochondrial biogenesis in cerebral ischemia.
Journal: International journal of molecular sciences 20110101
Title: Differential expression of Wnts after spinal cord contusion injury in adult rats.
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Title: Mortality from Parkinson's disease and other causes among a workforce manufacturing paraquat: a retrospective cohort study.
Journal: BMJ open 20110101
Title: Moving forward: advances in the treatment of movement disorders with deep brain stimulation.
Journal: Frontiers in integrative neuroscience 20110101
Title: Neuromelanin is an immune stimulator for dendritic cells in vitro.
Journal: BMC neuroscience 20110101
Title: A TNF receptor 2 selective agonist rescues human neurons from oxidative stress-induced cell death.
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Title: Differential regional expression patterns of α-synuclein, TNF-α, and IL-1β; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment.
Journal: Journal of neuroinflammation 20110101
Title: Interaction between α-synuclein and other proteins in neurodegenerative disorders.
Journal: TheScientificWorldJournal 20110101
Title: The promise of neuroprotective agents in Parkinson's disease.
Journal: Frontiers in neurology 20110101
Title: Acupuncture enhances the synaptic dopamine availability to improve motor function in a mouse model of Parkinson's disease.
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Title: Oxidation of DJ-1 induced by 6-hydroxydopamine decreasing intracellular glutathione.
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Title: History of innate immunity in neurodegenerative disorders.
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Title: Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors.
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Title: Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study.
Journal: Medical gas research 20110101
Title: The 2011 Medical Molecular Hydrogen Symposium: An inaugural symposium of the journal Medical Gas Research.
Journal: Medical gas research 20110101
Title: Application of medical gases in the field of neurobiology.
Journal: Medical gas research 20110101
Title: Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide.
Journal: Medical gas research 20110101
Title: Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.
Journal: Medical gas research 20110101
Title: Oxidative stress in neurodegenerative diseases: mechanisms and therapeutic perspectives.
Journal: Oxidative medicine and cellular longevity 20110101
Title: Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice.
Journal: PloS one 20110101
Title: Resveratrol protects rats from Aβ-induced neurotoxicity by the reduction of iNOS expression and lipid peroxidation.
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Title: Apoptosis Induced by Manganese on Neuronal SK-N-MC Cell Line: Endoplasmic Reticulum (ER) Stress and Mitochondria Dysfunction.
Journal: Environmental health and toxicology 20110101
Title: The translational value of the MPTP non-human primate model of Parkinsonism for deep brain stimulation research.
Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20110101
Title: Inter-hemispheric asymmetry of nigrostriatal dopaminergic lesion: a possible compensatory mechanism in Parkinson's disease.
Journal: Frontiers in systems neuroscience 20110101
Title: A role for locus coeruleus in Parkinson tremor.
Journal: Frontiers in human neuroscience 20110101
Title: Correlation transfer from basal ganglia to thalamus in Parkinson's disease.
Journal: Frontiers in computational neuroscience 20110101
Title: Inflammatory Animal Model for Parkinson's Disease: The Intranigral Injection of LPS Induced the Inflammatory Process along with the Selective Degeneration of Nigrostriatal Dopaminergic Neurons.
Journal: ISRN neurology 20110101
Title: Serine 129 Phosphorylation of α-Synuclein Cross-Links with Tissue Transglutaminase to Form Lewy Body-Like Inclusion Bodies.
Journal: ISRN neurology 20110101
Title: Peripheral vs. Central Sex Steroid Hormones in Experimental Parkinson's Disease.
Journal: Frontiers in endocrinology 20110101
Title: Male/Female differences in neuroprotection and neuromodulation of brain dopamine.
Journal: Frontiers in endocrinology 20110101
Title: Microdialysis study of striatal dopamine in MPTP-hemilesioned rats challenged with apomorphine and amphetamine.
Journal: Behavioural brain research 20101220
Title: Exercise elevates dopamine D2 receptor in a mouse model of Parkinson's disease: in vivo imaging with [¹⁸F]fallypride.
Journal: Movement disorders : official journal of the Movement Disorder Society 20101215
Title: Functional proteomic analysis for regulatory T cell surveillance of the HIV-1-infected macrophage.
Journal: Journal of proteome research 20101203
Title: Exercise effects on motor and affective behavior and catecholamine neurochemistry in the MPTP-lesioned mouse.
Journal: Behavioural brain research 20101201
Title: Protective effects of Chunghyuldan against ROS-mediated neuronal cell death in models of Parkinson's disease.
Journal: Basic & clinical pharmacology & toxicology 20101201
Title: Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia.
Journal: Neurobiology of disease 20101201
Title: Metabolic activity of the subthalamic nucleus in a primate model of L-dopa-unresponsive parkinsonism.
Journal: Neurological research 20101201
Title: Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model.
Journal: Free radical biology & medicine 20101201
Title: The partial dopamine agonist pardoprunox (SLV308) administered in combination with l-dopa improves efficacy and decreases dyskinesia in MPTP treated common marmosets.
Journal: Experimental neurology 20101201
Title: Proanthocyanidin-rich fraction from Croton celtidifolius Baill confers neuroprotection in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine rat model of Parkinson's disease.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20101201
Title: Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP.
Journal: Nature neuroscience 20101201
Title: Effects of rotenone and other mitochondrial complex I inhibitors on the brine shrimp Artemia.
Journal: Acta biologica Hungarica 20101201
Title: Oxidative stress induced by the Fe/ascorbic acid system or model ischemia in vitro: effect of carvedilol and pyridoindole antioxidant SMe1EC2 in young and adult rat brain tissue.
Journal: Interdisciplinary toxicology 20101201
Title: Mesenchymal stem cells for treatment of CNS injury.
Journal: Current neuropharmacology 20101201
Title: The role of axonopathy in Parkinson's disease.
Journal: Experimental neurobiology 20101201
Title: Gene disruption of caspase-3 prevents MPTP-induced Parkinson's disease in mice.
Journal: Biochemical and biophysical research communications 20101112
Title: Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer's and Parkinson's diseases.
Journal: Apoptosis : an international journal on programmed cell death 20101101
Title: Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease.
Journal: Cellular and molecular life sciences : CMLS 20101101
Title: Selenium partially reverses the depletion of striatal dopamine and its metabolites in MPTP-treated C57BL mice.
Journal: Neurochemistry international 20101101
Title: The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6.
Journal: Free radical research 20101101
Title: Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia.
Journal: Annals of neurology 20101101
Title: Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples.
Journal: Archives of toxicology 20101101
Title: [Effects of subchronic hemantane administration on dopamine and serotonin receptors in intact and MPP+-treated rat brain ex vivo].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20101101
Title: Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals.
Journal: Neuroscience letters 20101015
Title: Pardoprunox reverses motor deficits but induces only mild dyskinesia in MPTP-treated common marmosets.
Journal: Movement disorders : official journal of the Movement Disorder Society 20101015
Title: Substance abuse and movement disorders.
Journal: Movement disorders : official journal of the Movement Disorder Society 20101015
Title: MPTP-induced parkinsonism extends to a subclass of TH-positive neurons in the gut.
Journal: Brain research 20101008
Title: Cortical regulation of striatal medium spiny neuron dendritic remodeling in parkinsonism: modulation of glutamate release reverses dopamine depletion-induced dendritic spine loss.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20101001
Title: Neuroprotective and anti-inflammatory activities of ketogenic diet on MPTP-induced neurotoxicity.
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Title: Intranigral LPS administration produces dopamine, glutathione but not behavioral impairment in comparison to MPTP and 6-OHDA neurotoxin models of Parkinson's disease.
Journal: Neurochemical research 20101001
Title: Dopaminergic cell damage and vulnerability to MPTP in Pink1 knockdown zebrafish.
Journal: Neurobiology of disease 20101001
Title: N(ɛ)-(carboxymethyl)lysine linkage to α-synuclein and involvement of advanced glycation end products in α-synuclein deposits in an MPTP-intoxicated mouse model.
Journal: Biochimie 20101001
Title: Preladenant, a selective A(2A) receptor antagonist, is active in primate models of movement disorders.
Journal: Experimental neurology 20101001
Title: Licofelone attenuates MPTP-induced neuronal toxicity: behavioral, biochemical and cellular evidence.
Journal: Inflammopharmacology 20101001
Title: Oestrogen receptor beta ligand: a novel treatment to enhance endogenous functional remyelination.
Journal: Brain : a journal of neurology 20101001
Title: Experimental model of combined pain and depression status in rats.
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Title: [Pathophysiology of Parkinson's disease: an update].
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Title: The effects of docosahexaenoic acid on glial derived neurotrophic factor and neurturin in bilateral rat model of Parkinson's disease.
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Title: Neuroprotective effects of an herbal medicine, Yi-Gan San on MPP+/MPTP-induced cytotoxicity in vitro and in vivo.
Journal: Journal of ethnopharmacology 20100915
Title: Pathogenic lysosomal depletion in Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100915
Title: Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD.
Journal: Neuroscience letters 20100906
Title: HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20100901
Title: Gene-environment interactions in Parkinson's disease and other forms of parkinsonism.
Journal: Neurotoxicology 20100901
Title: A direct projection from the subthalamic nucleus to the ventral thalamus in monkeys.
Journal: Neurobiology of disease 20100901
Title: Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration.
Journal: Neuroscience 20100901
Title: Inhibition of inducible nitric oxide synthase expression and cell death by (-)-epigallocatechin-3-gallate, a green tea catechin, in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100901
Title: Functional disconnection of the substantia nigra pars compacta from the pedunculopontine nucleus impairs learning of a conditioned avoidance task.
Journal: Neurobiology of learning and memory 20100901
Title: The roles of the thioredoxin system and peroxiredoxins in 1-methyl-4-phenyl-pyridinium ion-induced cytotoxicity in rat pheochromocytoma cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100901
Title: Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.
Journal: Bioorganic & medicinal chemistry letters 20100901
Title: Amelioration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced behavioural dysfunction and oxidative stress by Pycnogenol in mouse model of Parkinson's disease.
Journal: Behavioural pharmacology 20100901
Title: The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures.
Journal: The international journal of neuropsychopharmacology 20100901
Title: Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease.
Journal: British journal of pharmacology 20100901
Title: Therapeutic effect of a novel anti-parkinsonian agent zonisamide against MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine) neurotoxicity in mice.
Journal: Metabolic brain disease 20100901
Title: PINK1 and Parkin to control mitochondria remodeling.
Journal: Anatomy & cell biology 20100901
Title: Melatonin metabolism in the central nervous system.
Journal: Current neuropharmacology 20100901
Title: The role of mitochondria in brain aging and the effects of melatonin.
Journal: Current neuropharmacology 20100901
Title: Neurotoxins: free radical mechanisms and melatonin protection.
Journal: Current neuropharmacology 20100901
Title: Neurotoxic effects of tetrahydroisoquinolines and underlying mechanisms.
Journal: Experimental neurobiology 20100901
Title: Role of cortical and striatal 5-HT1A receptors in alleviating antipsychotic-induced extrapyramidal disorders.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100816
Title: Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100816
Title: Novel D3 dopamine receptor-preferring agonist D-264: Evidence of neuroprotective property in Parkinson's disease animal models induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and lactacystin.
Journal: Journal of neuroscience research 20100815
Title: MPTP treatment increases expression of pre-pro-nociceptin/orphanin FQ mRNA in a subset of substantia nigra reticulata neurons.
Journal: Neuroscience 20100811
Title: Mesencephalic and striatal protein profiles in mice over-expressing glucose-6-phosphate dehydrogenase in dopaminergic neurons.
Journal: Journal of proteomics 20100805
Title: Decreased RGS9 protein level in the striatum of rodents undergoing MPTP or 6-OHDA neurotoxicity.
Journal: Neuroscience letters 20100802
Title: An in vivo pharmacological evaluation of pardoprunox (SLV308)--a novel combined dopamine D(2)/D(3) receptor partial agonist and 5-HT(1A) receptor agonist with efficacy in experimental models of Parkinson's disease.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100801
Title: Cellular localization of the organic cation transporters, OCT1 and OCT2, in brain microvessel endothelial cells and its implication for MPTP transport across the blood-brain barrier and MPTP-induced dopaminergic toxicity in rodents.
Journal: Journal of neurochemistry 20100801
Title: alpha-Synuclein- and MPTP-generated rodent models of Parkinson's disease and the study of extracellular striatal dopamine dynamics: a microdialysis approach.
Journal: CNS & neurological disorders drug targets 20100801
Title: Macrophage-mediated GDNF delivery protects against dopaminergic neurodegeneration: a therapeutic strategy for Parkinson's disease.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20100801
Title: Promise and pitfalls of animal models of schizophrenia.
Journal: Current psychiatry reports 20100801
Title: The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia.
Journal: Acta neuropathologica 20100801
Title: Morin exerts neuroprotective actions in Parkinson disease models in vitro and in vivo.
Journal: Acta pharmacologica Sinica 20100801
Title: Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins.
Journal: Annals of neurology 20100801
Title: Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans.
Journal: PLoS genetics 20100801
Title: Effect of histamine H2 receptor antagonism on levodopa-induced dyskinesia in the MPTP-macaque model of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20100730
Title: Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease.
Journal: Brain research 20100730
Title: Gene expression profiling in progressively MPTP-lesioned macaques reveals molecular pathways associated with sporadic Parkinson's disease.
Journal: Brain research 20100730
Title: Microglial activation and age-related dopaminergic neurodegeneration in MPTP-treated SAMP8 mice.
Journal: Brain research 20100723
Title: Meloxicam protects cell damage from 1-methyl-4-phenyl pyridinium toxicity via the phosphatidylinositol 3-kinase/Akt pathway in human dopaminergic neuroblastoma SH-SY5Y cells.
Journal: Brain research 20100716
Title: Salicylic acid protects against chronic L-DOPA-induced 6-OHDA generation in experimental model of parkinsonism.
Journal: Brain research 20100716
Title: Objective and quantitative evaluation of motor function in a monkey model of Parkinson's disease.
Journal: Journal of neuroscience methods 20100715
Title: Paroxetine prevents loss of nigrostriatal dopaminergic neurons by inhibiting brain inflammation and oxidative stress in an experimental model of Parkinson's disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20100715
Title: Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100714
Title: VTA neurons show a potentially protective transcriptional response to MPTP.
Journal: Brain research 20100709
Title: Paraquat and Parkinson's disease.
Journal: Cell death and differentiation 20100701
Title: Hexokinase II gene transfer protects against neurodegeneration in the rotenone and MPTP mouse models of Parkinson's disease.
Journal: Journal of neuroscience research 20100701
Title: Mulberry fruit protects dopaminergic neurons in toxin-induced Parkinson's disease models.
Journal: The British journal of nutrition 20100701
Title: Calcium-permeable AMPA receptors are involved in the induction and expression of l-DOPA-induced dyskinesia in Parkinson's disease.
Journal: Journal of neurochemistry 20100701
Title: Estrogen reduces BDNF level, but maintains dopaminergic cell density in the striatum of MPTP mouse model.
Journal: The International journal of neuroscience 20100701
Title: Metabolic changes detected in vivo by 1H MRS in the MPTP-intoxicated mouse.
Journal: NMR in biomedicine 20100701
Title: Exercise protects against MPTP-induced neurotoxicity in mice.
Journal: Brain research 20100623
Title: Time course of MPTP toxicity on translational control protein expression in mice brain.
Journal: Toxicology letters 20100616
Title: A rotarod test for evaluation of motor skill learning.
Journal: Journal of neuroscience methods 20100615
Title: The timing of administration, dose dependence and efficacy of dopa decarboxylase inhibitors on the reversal of motor disability produced by L-DOPA in the MPTP-treated common marmoset.
Journal: European journal of pharmacology 20100610
Title: Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.
Journal: The Journal of biological chemistry 20100604
Title: Effects of cysteamine on MPTP-induced dopaminergic neurodegeneration in mice.
Journal: Brain research 20100604
Title: Changes of AMPA receptors in MPTP monkeys with levodopa-induced dyskinesias.
Journal: Neuroscience 20100602
Title: Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys.
Journal: Neuropharmacology 20100601
Title: Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade.
Journal: Experimental neurology 20100601
Title: Protective effects of heme oxygenase-1 against MPP(+)-induced cytotoxicity in PC-12 cells.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20100601
Title: Localization and function of GABA transporters in the globus pallidus of parkinsonian monkeys.
Journal: Experimental neurology 20100601
Title: Genes regulated in MPTP-treated macaques and human Parkinson's disease suggest a common signature in prefrontal cortex.
Journal: Neurobiology of disease 20100601
Title: Dopaminergic cells in the periaqueductal grey matter of MPTP-treated monkeys and mice; patterns of survival and effect of deep brain stimulation and lesion of the subthalamic nucleus.
Journal: Parkinsonism & related disorders 20100601
Title: Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 20100601
Title: Sex differences in motor behavior in the MPTP mouse model of Parkinson's disease.
Journal: Pharmacology, biochemistry, and behavior 20100601
Title: Post-MPTP treatment with granulocyte colony-stimulating factor improves nigrostriatal function in the mouse model of Parkinson's disease.
Journal: Molecular neurobiology 20100601
Title: Therapeutic effect of a novel anti-parkinsonian agent zonisamide against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice.
Journal: Metabolic brain disease 20100601
Title: Biochemical alterations of the striatum in an MPTP-treated mouse model of Parkinson's disease.
Journal: Metabolic brain disease 20100601
Title: Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial.
Journal: The Lancet. Neurology 20100601
Title: Interactions of 1-methyl-3-phenylpyrrolidine and 3-methyl-1-phenyl-3-azabicyclo[3.1.0]hexane with monoamine oxidase B.
Journal: Bioorganic & medicinal chemistry 20100601
Title: Aged Tgfbeta2/Gdnf double-heterozygous mice show no morphological and functional alterations in the nigrostriatal system.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20100601
Title: Effect of preferential cyclooxygenase-2 (COX-2) inhibitor against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced striatal lesions in rats: behavioral, biochemical and histological evidences.
Journal: Indian journal of experimental biology 20100601
Title: Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents.
Journal: Experimental neurobiology 20100601
Title: Poly(ADP-ribose)polymerase inhibitor can attenuate the neuronal death after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice.
Journal: Journal of neuroscience research 20100515
Title: Towards model-based control of Parkinson's disease.
Journal: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20100513
Title: Prosurvival effect of human wild-type alpha-synuclein on MPTP-induced toxicity to central but not peripheral catecholaminergic neurons isolated from transgenic mice.
Journal: Neuroscience 20100505
Title: Neuroprotection by caffeine: time course and role of its metabolites in the MPTP model of Parkinson's disease.
Journal: Neuroscience 20100505
Title: Chronic administration with rotenone does not enhance MPTP neurotoxicity in C57BL/6 mice.
Journal: Journal of molecular neuroscience : MN 20100501
Title: Effect of L-Dopa on metabotropic glutamate receptor 5 in the brain of parkinsonian monkeys.
Journal: Journal of neurochemistry 20100501
Title: Differing short-term neuroprotective effects of the fibrates fenofibrate and bezafibrate in MPTP and 6-OHDA experimental models of Parkinson's disease.
Journal: Behavioural pharmacology 20100501
Title: Drinking hydrogen water ameliorated cognitive impairment in senescence-accelerated mice.
Journal: Journal of clinical biochemistry and nutrition 20100501
Title: Insulin like growth factor-1 prevents 1-mentyl-4-phenylphyridinium-induced apoptosis in PC12 cells through activation of glycogen synthase kinase-3beta.
Journal: Toxicology 20100430
Title: Nicotine- and caffeine-mediated changes in gene expression patterns of MPTP-lesioned mouse striatum: Implications in neuroprotection mechanism.
Journal: Chemico-biological interactions 20100429
Title: Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.
Journal: Neuroscience 20100428
Title: Protocatechuic acid inhibits neurotoxicity induced by MPTP in vivo.
Journal: Neuroscience letters 20100426
Title: Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinson's disease.
Journal: Science translational medicine 20100421
Title: Striatal Akt/GSK3 signaling pathway in the development of L-Dopa-induced dyskinesias in MPTP monkeys.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100416
Title: Ethyl pyruvate has a neuroprotective effect through activation of extracellular signal-regulated kinase in Parkinson's disease model.
Journal: Biochemical and biophysical research communications 20100409
Title: Nest building performance following MPTP toxicity in mice.
Journal: Behavioural brain research 20100402
Title: Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease.
Journal: Glia 20100401
Title: MPTP-induced dopaminergic degeneration and deficits in object recognition in rats are accompanied by neuroinflammation in the hippocampus.
Journal: Pharmacology, biochemistry, and behavior 20100401
Title: Transient elevation of adult hippocampal neurogenesis after dopamine depletion.
Journal: Experimental neurology 20100401
Title: Vulnerability of peripheral catecholaminergic neurons to MPTP is not regulated by alpha-synuclein.
Journal: Neurobiology of disease 20100401
Title: Preventive role of PD-1 on MPTP-induced dopamine depletion in mice.
Journal: Cell biochemistry and function 20100401
Title: Detection of MPTP-induced substantia nigra hyperechogenicity in Rhesus monkeys by transcranial ultrasound.
Journal: Ultrasound in medicine & biology 20100401
Title: Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4-phenylpyridinium toxicity in SH-SY5Y neuronal cells.
Journal: The European journal of neuroscience 20100401
Title: Cellular repair in the parkinsonian nonhuman primate brain.
Journal: Rejuvenation research 20100401
Title: Involvement of NMDA receptors in both MPTP-induced neuroinflammation and deficits in episodic-like memory in Wistar rats.
Journal: Behavioural brain research 20100317
Title: A new ethyladenine antagonist of adenosine A(2A) receptors: behavioral and biochemical characterization as an antiparkinsonian drug.
Journal: Neuropharmacology 20100301
Title: Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20100301
Title: Environmental toxins and Parkinson's disease: putative roles of impaired electron transport chain and oxidative stress.
Journal: Toxicology and industrial health 20100301
Title: Ultrastructural localization and function of dopamine D1-like receptors in the substantia nigra pars reticulata and the internal segment of the globus pallidus of parkinsonian monkeys.
Journal: The European journal of neuroscience 20100301
Title: [Experimental modeling of functional deficiency of the nigrostriatal dopaminergic system in mice].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20100301
Title: Cyclooxygenase and neuroinflammation in Parkinson's disease neurodegeneration.
Journal: Current neuropharmacology 20100301
Title: Altered AMPA receptor expression with treadmill exercise in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury.
Journal: Journal of neuroscience research 20100215
Title: A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20100209
Title: Neuroprotective effect of PACAP on translational control alteration and cognitive decline in MPTP parkinsonian mice.
Journal: Neurotoxicity research 20100201
Title: Single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice models early preclinical phase of Parkinson's disease.
Journal: Neurotoxicity research 20100201
Title: Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model.
Journal: Journal of neuroscience research 20100201
Title: Synaptic recruitment of AMPA glutamate receptor subunits in levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate.
Journal: Synapse (New York, N.Y.) 20100201
Title: Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease.
Journal: Free radical biology & medicine 20100201
Title: The antiepileptic drug zonisamide inhibits MAO-B and attenuates MPTP toxicity in mice: clinical relevance.
Journal: Experimental neurology 20100201
Title: Small peptide inhibitor of JNKs protects against MPTP-induced nigral dopaminergic injury via inhibiting the JNK-signaling pathway.
Journal: Laboratory investigation; a journal of technical methods and pathology 20100201
Title: Molecular modeling study of 4-phenylpiperazine and 4-phenyl-1,2,3,6-tetrahydropyridine derivatives: a new step towards the design of high-affinity 5-HT1A ligands.
Journal: Bioorganic & medicinal chemistry letters 20100201
Title: Gene expression profile of acupuncture treatment in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease model.
Journal: Neurological research 20100201
Title: Neuroprotective effects of bee venom pharmaceutical acupuncture in acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.
Journal: Neurological research 20100201
Title: Neuroprotective effect of Centella asiatica extract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats.
Journal: The Journal of toxicological sciences 20100201
Title: [Caffeine as a preventive drug for Parkinson's disease: epidemiologic evidence and experimental support].
Journal: Revista de neurologia 20100201
Title: Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway.
Journal: Rejuvenation research 20100201
Title: Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120
Title: BDNF levels are not related with levodopa-induced dyskinesias in MPTP monkeys.
Journal: Movement disorders : official journal of the Movement Disorder Society 20100115
Title: Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease.
Journal: Brain research 20100108
Title: Increased expression of erythropoietin receptor in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced Parkinsonian model.
Journal: Physiological research 20100101
Title: Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides.
Journal: Neuropharmacology 20100101
Title: Effects of hydroxysafflor yellow A in the attenuation of MPTP neurotoxicity in mice.
Journal: Neurochemical research 20100101
Title: Role of PPARs in Radiation-Induced Brain Injury.
Journal: PPAR research 20100101
Title: The dopamine D(2) receptor partial agonist aplindore improves motor deficits in MPTP-treated common marmosets alone and combined with L-dopa.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20100101
Title: Potentiation of methamphetamine neurotoxicity by intrastriatal lipopolysaccharide administration.
Journal: Neurochemistry international 20100101
Title: Neuroprotection of midbrain dopaminergic cells in MPTP-treated mice after near-infrared light treatment.
Journal: The Journal of comparative neurology 20100101
Title: Cerebral bioimaging of Cu, Fe, Zn, and Mn in the MPTP mouse model of Parkinson's disease using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS).
Journal: Journal of the American Society for Mass Spectrometry 20100101
Title: AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Biochemical and biophysical research communications 20100101
Title: Treadmill gait analysis characterizes gait alterations in Parkinson's disease and amyotrophic lateral sclerosis mouse models.
Journal: Journal of motor behavior 20100101
Title: L-DOPA-induced 6-hydroxydopamine production in the striata of rodents is sensitive to the degree of denervation.
Journal: Neurochemistry international 20100101
Title: Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice.
Journal: Brain : a journal of neurology 20100101
Title: Indirubins deplete striatal monoamines in the Intact and MPTP-treated mouse brain and block kainate-induced striatal astrogliosis.
Journal: Neurotoxicology and teratology 20100101
Title: Owner reports of attention, activity, and impulsivity in dogs: a replication study.
Journal: Behavioral and brain functions : BBF 20100101
Title: Caffeine and a selective adenosine A2A receptor antagonist induce sensitization and cross-sensitization behavior associated with increased striatal dopamine in mice.
Journal: Journal of biomedical science 20100101
Title: Interleukin 18 in the CNS.
Journal: Journal of neuroinflammation 20100101
Title: Melatonin and structurally-related compounds protect synaptosomal membranes from free radical damage.
Journal: International journal of molecular sciences 20100101
Title: Neuropsychiatric behaviors in the MPTP marmoset model of Parkinson's disease.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100101
Title: Neuroprotective and neurotoxic phenotypes of activated microglia in neonatal mice with respective MPTP- and ethanol-induced brain injury.
Journal: Neuro-degenerative diseases 20100101
Title: Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy.
Journal: PloS one 20100101
Title: Destruction of dopaminergic neurons in the midbrain by 6-hydroxydopamine decreases hippocampal cell proliferation in rats: reversal by fluoxetine.
Journal: PloS one 20100101
Title: Cellular stress responses: cell survival and cell death.
Journal: International journal of cell biology 20100101
Title: Low dosage of rasagiline and epigallocatechin gallate synergistically restored the nigrostriatal axis in MPTP-induced parkinsonism.
Journal: Neuro-degenerative diseases 20100101
Title: Social odor recognition: a novel behavioral model for cognitive dysfunction in Parkinson's disease.
Journal: Neuro-degenerative diseases 20100101
Title: Effects of Pharmacological Block of GABA(A) Receptors on Pallidal Neurons in Normal and Parkinsonian State.
Journal: Frontiers in cellular neuroscience 20100101
Title: Does the difference between physically active and couch potato lie in the dopamine system?
Journal: International journal of biological sciences 20100101
Title: Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro.
Journal: PloS one 20100101
Title: Parkinson's disease: functional changes in frontal and parietal cortex using 18 F- fluoro-deoxy glucose positron emission tomography/computed tomography.
Journal: Neurology India 20100101
Title: Microglia in the aging brain: relevance to neurodegeneration.
Journal: Molecular neurodegeneration 20100101
Title: [Study of extracellular concentration of dopamine and its metabolites in mice striatum by a microdialysis technique at intraperitoneal administration of MPTP].
Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20100101
Title: 5-HT2A receptor antagonists improve motor impairments in the MPTP mouse model of Parkinson's disease.
Journal: Neuropharmacology 20100101
Title: Risk of Parkinson's disease after tamoxifen treatment.
Journal: BMC neurology 20100101
Title: Nitrated alpha-synuclein induces the loss of dopaminergic neurons in the substantia nigra of rats.
Journal: PloS one 20100101
Title: Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease.
Journal: Molecular neurodegeneration 20100101
Title: Kainic acid-induced microglial activation is attenuated in aged interleukin-18 deficient mice.
Journal: Journal of neuroinflammation 20100101
Title: Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.
Journal: PloS one 20100101
Title: Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.
Journal: BMC neuroscience 20100101
Title: Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model.
Journal: BMC neuroscience 20100101
Title: Animal models of neurological disease.
Journal: Advances in experimental medicine and biology 20100101
Title: Cassiae semen, a seed of Cassia obtusifolia, has neuroprotective effects in Parkinson's disease models.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Title: Effect of prolonged exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brain.
Journal: Particle and fibre toxicology 20100101
Title: Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS.
Journal: PloS one 20100101
Title: GT1b-induced neurotoxicity is mediated by the Akt/GSK-3/tau signaling pathway but not caspase-3 in mesencephalic dopaminergic neurons.
Journal: BMC neuroscience 20100101
Title: Selective neuronal vulnerability to oxidative stress in the brain.
Journal: Frontiers in aging neuroscience 20100101
Title: Endurance exercise training promotes angiogenesis in the brain of chronic/progressive mouse model of Parkinson's Disease.
Journal: NeuroRehabilitation 20100101
Title: Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis.
Journal: Frontiers in aging neuroscience 20100101
Title: Reduction of L-type amino acid transporter 1 mRNA expression in brain capillaries in a mouse model of Parkinson's disease.
Journal: Biological & pharmaceutical bulletin 20100101
Title: A53T-alpha-synuclein overexpression impairs dopamine signaling and striatal synaptic plasticity in old mice.
Journal: PloS one 20100101
Title: [Modeling of preclinical and early clinical stages of Parkinson's disease].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
Title: Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP).
Journal: PloS one 20100101
Title: Different susceptibility to the Parkinson's toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1.
Journal: PloS one 20100101
Title: Computational physiology of the basal ganglia in Parkinson's disease.
Journal: Progress in brain research 20100101
Title: Electrophysiological characteristics of globus pallidus neurons.
Journal: PloS one 20100101
Title: [Oxidative processes and lipid metabolism in the experimental induced Parkinsonian syndrome].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
Title: [Optimization of counting process of dopaminergic neurons in substantia nigra of parkinsonian mice].
Journal: Tsitologiia 20100101
Title: Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice.
Journal: PloS one 20100101
Title: Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia.
Journal: PloS one 20100101
Title: Neuroprotective effect of gypenosides against oxidative injury in the substantia nigra of a mouse model of Parkinson's disease.
Journal: The Journal of international medical research 20100101
Title: Role of nitric oxide and its metabolites as potential markers in lung cancer.
Journal: Annals of thoracic medicine 20100101
Title: Mitochondrial preconditioning: a potential neuroprotective strategy.
Journal: Frontiers in aging neuroscience 20100101
Title: Zonisamide attenuates MPTP neurotoxicity in marmosets.
Journal: Journal of pharmacological sciences 20100101
Title: Neuroprotection and Functional Recovery Associated with Decreased Microglial Activation Following Selective Activation of mGluR2/3 Receptors in a Rodent Model of Parkinson's Disease.
Journal: Parkinson's disease 20100101
Title: Oxidative stress in skin fibroblasts cultures from patients with Parkinson's disease.
Journal: BMC neurology 20100101
Title: Neuroanatomical study of the A11 diencephalospinal pathway in the non-human primate.
Journal: PloS one 20100101
Title: Subtle cardiovascular dysfunction in the unilateral 6-hydroxydopamine-lesioned rat.
Journal: Parkinson's disease 20100101
Title: Fcγ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson's disease.
Journal: Molecular neurodegeneration 20100101
Title: Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.
Journal: PloS one 20100101
Title: Protein aggregation containing β-amyloid, α-synuclein and hyperphosphorylated τ in cultured cells of hippocampus, substantia nigra and locus coeruleus after rotenone exposure.
Journal: BMC neuroscience 20100101
Title: Estrogens of multiple classes and their role in mental health disease mechanisms.
Journal: International journal of women's health 20100101
Title: Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes.
Journal: Molecular brain 20100101
Title: Vulnerability of mesostriatal dopaminergic neurons in Parkinson's disease.
Journal: Frontiers in neuroanatomy 20100101
Title: Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal: Journal of neuroinflammation 20100101
Title: Catechol-O-methyltransferase inhibitors in preclinical models as adjuncts of L-dopa treatment.
Journal: International review of neurobiology 20100101
Title: In vivo imaging of retinal gliosis: a platform for diagnosis of PD and Screening of anti-PD compounds.
Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20100101
Title: Modeling the motor striatum under Deep Brain Stimulation in normal and MPTP conditions.
Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20100101
Title: Modeling the effects of Deep Brain Stimulation on sensorimotor cortex in normal and MPTP conditions.
Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20100101
Title: Extrastriatal dopaminergic circuits of the Basal Ganglia.
Journal: Frontiers in neuroanatomy 20100101
Title: The New Inhibitor of Monoamine Oxidase, M30, has a Neuroprotective Effect Against Dexamethasone-Induced Brain Cell Apoptosis.
Journal: Frontiers in neuroscience 20100101
Title: Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity.
Journal: PloS one 20100101
Title: Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys.
Journal: PloS one 20100101
Title: Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport.
Journal: Journal of biomedical science 20100101
Title: ER stress response plays an important role in aggregation of α-synuclein.
Journal: Molecular neurodegeneration 20100101
Title: Role of Basal Ganglia in sleep-wake regulation: neural circuitry and clinical significance.
Journal: Frontiers in neuroanatomy 20100101
Title: Parkinson's disease: is it a toxic syndrome?
Journal: Neurology research international 20100101
Title: Striatal spine plasticity in Parkinson's disease.
Journal: Frontiers in neuroanatomy 20100101
Title: Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder.
Journal: International journal of tryptophan research : IJTR 20100101
Title: Mitochondrial therapy for Parkinson's disease: neuroprotective pharmaconutrition may be disease-modifying.
Journal: Clinical pharmacology : advances and applications 20100101
Title: Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091216
Title: Elevated interleukin-1beta induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine aggravating dopaminergic neurodegeneration in old male mice.
Journal: Brain research 20091211
Title: Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats.
Journal: Pharmacology, biochemistry, and behavior 20091201
Title: CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20091201
Title: Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys.
Journal: Human gene therapy 20091201
Title: MPTP lesion causes neuroinflammation and deficits in object recognition in Wistar rats.
Journal: Behavioral neuroscience 20091201
Title: Striatal spine plasticity in Parkinson's disease: pathological or not?
Journal: Parkinsonism & related disorders 20091201
Title: Iron transport in Parkinson's disease.
Journal: Parkinsonism & related disorders 20091201
Title: Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency.
Journal: Parkinsonism & related disorders 20091201
Title: Do mtDNA Mutations Participate in the Pathogenesis of Sporadic Parkinson's Disease?
Journal: Current genomics 20091201
Title: Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells.
Journal: Toxicology and applied pharmacology 20091115
Title: Gender differences on MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in C57BL/6 mice.
Journal: Molecular and cellular endocrinology 20091113
Title: Modulation of brain-derived neurotrophic factor as a potential neuroprotective mechanism of action of omega-3 fatty acids in a parkinsonian animal model.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20091113
Title: Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091111
Title: Cruciferous nutraceutical 3H-1,2-dithiole-3-thione protects human primary astrocytes against neurocytotoxicity elicited by MPTP, MPP(+), 6-OHDA, HNE and acrolein.
Journal: Neurochemical research 20091101
Title: Doxycycline is neuroprotective against nigral dopaminergic degeneration by a dual mechanism involving MMP-3.
Journal: Neurotoxicity research 20091101
Title: MPTP-induced neuroblast apoptosis in the subventricular zone is not regulated by dopamine or other monoamine transporters.
Journal: Neurotoxicology 20091101
Title: Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study.
Journal: Journal of neurochemistry 20091101
Title: Melatonin inhibits 6-hydroxydopamine production in the brain to protect against experimental parkinsonism in rodents.
Journal: Journal of pineal research 20091101
Title: Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091028
Title: Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease.
Journal: The Journal of biological chemistry 20091016
Title: JNK inhibitor protects dopaminergic neurons by reducing COX-2 expression in the MPTP mouse model of subacute Parkinson's disease.
Journal: Journal of the neurological sciences 20091015
Title: Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia.
Journal: Science translational medicine 20091014
Title: Toxic influence of chronic oral administration of paraquat on nigrostriatal dopaminergic neurons in C57BL/6 mice.
Journal: Chinese medical journal 20091005
Title: Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection.
Journal: Biochemical and biophysical research communications 20091002
Title: Alterations of nocturnal activity in rats following subchronic oral administration of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20091001
Title: Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease.
Journal: Free radical biology & medicine 20091001
Title: Sleep disorders in Parkinson's disease: the contribution of the MPTP non-human primate model.
Journal: Experimental neurology 20091001
Title: Nur77 mRNA levels and L-Dopa-induced dyskinesias in MPTP monkeys treated with docosahexaenoic acid.
Journal: Neurobiology of disease 20091001
Title: Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).
Journal: Free radical research 20091001
Title: Effects of a novel dopamine uptake inhibitor upon extracellular dopamine from superfused murine striatal tissue.
Journal: European journal of pharmacology 20091001
Title: Effects of pergolide mesilate on metallothionein mRNAs expression in a mouse model for Parkinson disease.
Journal: Biological & pharmaceutical bulletin 20091001
Title: [Neuroprotective effects and mechanisms of Chuanxiong Chatiao pulvis against MPTP-induced dopaminergic neurotoxicity in mice model of Parkinson's disease].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091001
Title: [Effection of Qing-Xuan tablets on behavior pattern and striatal TNF-alpha of Parkinson model mice].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091001
Title: MPTP administration increases plasma levels of acute phase proteins in non-human primates (Macaca fascicularis).
Journal: Neuroscience letters 20090929
Title: Withania somnifera root extract improves catecholamines and physiological abnormalities seen in a Parkinson's disease model mouse.
Journal: Journal of ethnopharmacology 20090925
Title: Iron-catalyzed selective oxidation of N-methyl amines: highly efficient synthesis of methylene-bridged bis-1,3-dicarbonyl compounds.
Journal: Organic letters 20090917
Title: Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease.
Journal: Biological psychiatry 20090915
Title: A novel anti-Parkinsonian agent, zonisamide, attenuates MPTP-induced neurotoxicity in mice.
Journal: Journal of molecular neuroscience : MN 20090901
Title: Mitochondria targeted peptides protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.
Journal: Antioxidants & redox signaling 20090901
Title: Pallidal stimulation that improves parkinsonian motor symptoms also modulates neuronal firing patterns in primary motor cortex in the MPTP-treated monkey.
Journal: Experimental neurology 20090901
Title: The blood-brain barrier is intact after levodopa-induced dyskinesias in parkinsonian primates--evidence from in vivo neuroimaging studies.
Journal: Neurobiology of disease 20090901
Title: Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease.
Journal: Experimental neurology 20090901
Title: Fucoidan protects against dopaminergic neuron death in vivo and in vitro.
Journal: European journal of pharmacology 20090901
Title: Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease.
Journal: The Journal of endocrinology 20090901
Title: Quantification of Paraquat, MPTP, and MPP+ in brain tissue using microwave-assisted solvent extraction (MASE) and high-performance liquid chromatography-mass spectrometry.
Journal: Analytical and bioanalytical chemistry 20090901
Title: Acute and chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administrations elicit similar microglial activation in the substantia nigra of monkeys.
Journal: Journal of neuropathology and experimental neurology 20090901
Title: Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles.
Journal: Journal of drug targeting 20090901
Title: TRPC1 inhibits apoptotic cell degeneration induced by dopaminergic neurotoxin MPTP/MPP(+).
Journal: Cell calcium 20090901
Title: The substantia nigra pars compacta of the Göttingen minipig: an anatomical and stereological study.
Journal: Brain structure & function 20090901
Title: Basal ganglia neuroprotection with anticonvulsants after energy stress: a comparative study.
Journal: Metabolic brain disease 20090901
Title: The neurotrophic and neuroprotective effects of psychotropic agents.
Journal: Dialogues in clinical neuroscience 20090901
Title: Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment.
Journal: Brain research 20090825
Title: Long term high frequency stimulation of STN increases dopamine in the corpus striatum of hemiparkinsonian rhesus monkey.
Journal: Brain research 20090825
Title: New MRI, 18F-DOPA and 11C-(+)-alpha-dihydrotetrabenazine templates for Macaca fascicularis neuroimaging: advantages to improve PET quantification.
Journal: NeuroImage 20090815
Title: Behavior, neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson's disease.
Journal: Physiology & behavior 20090804
Title: Effect of caffeine on the expression of cytochrome P450 1A2, adenosine A2A receptor and dopamine transporter in control and 1-methyl 4-phenyl 1, 2, 3, 6-tetrahydropyridine treated mouse striatum.
Journal: Brain research 20090804
Title: Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease.
Journal: Neurobiology of disease 20090801
Title: Not lost in translation Sensing the loss and filling the gap during regeneration.
Journal: Seminars in cell & developmental biology 20090801
Title: Redox activated MAP kinase death signaling cascade initiated by ASK1 is not activated in female mice following MPTP: novel mechanism of neuroprotection.
Journal: Neurotoxicity research 20090801
Title: Evidence for a dopaminergic innervation of the pedunculopontine nucleus in monkeys, and its drastic reduction after MPTP intoxication.
Journal: Journal of neurochemistry 20090801
Title: Effects of dopamine depletion on network entropy in the external globus pallidus.
Journal: Journal of neurophysiology 20090801
Title: Multipoint analysis of reduced (125)I-meta-iodobenzylguanidine uptake and norepinephrine turnover in the hearts of mice with 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine-induced parkinsonism.
Journal: Nuclear medicine and biology 20090801
Title: Neuroprotective effect of long-term NDI1 gene expression in a chronic mouse model of Parkinson disorder.
Journal: Rejuvenation research 20090801
Title: No Lewy pathology in monkeys with over 10 years of severe MPTP Parkinsonism.
Journal: Movement disorders : official journal of the Movement Disorder Society 20090730
Title: Low doses of sarizotan reduce dyskinesias and maintain antiparkinsonian efficacy of L-Dopa in parkinsonian monkeys.
Journal: Parkinsonism & related disorders 20090701
Title: Systemic administration of proteasome inhibitor protects against MPTP neurotoxicity in mice.
Journal: Cellular and molecular neurobiology 20090701
Title: Macroautophagy of the GPR37 orphan receptor and Parkinson disease-associated neurodegeneration.
Journal: Autophagy 20090701
Title: Neuroprotective actions of sex steroids in Parkinson's disease.
Journal: Frontiers in neuroendocrinology 20090701
Title: Cervical carotid and circle of willis arterial anatomy of macaque monkeys: a comparative anatomy study.
Journal: Anatomical record (Hoboken, N.J. : 2007) 20090701
Title: Blockade of PrRP attenuates MPTP-induced toxicity in mice.
Journal: Peptides 20090701
Title: Cortical serotonin and norepinephrine denervation in parkinsonism: preferential loss of the beaded serotonin innervation.
Journal: The European journal of neuroscience 20090701
Title: Risk is in the air: an intranasal MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) rat model of Parkinson's disease.
Journal: Annals of the New York Academy of Sciences 20090701
Title: Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins.
Journal: Brain research bulletin 20090630
Title: Activation of phosphatidylinositol-linked D1-like receptor modulates FGF-2 expression in astrocytes via IP3-dependent Ca2+ signaling.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090617
Title: Short-term depression of synaptic transmission during stimulation in the globus pallidus of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090617
Title: Two new test methods to quantify motor deficits in a marmoset model for Parkinson's disease.
Journal: Behavioural brain research 20090608
Title: Implication of NMDA receptors in the antidyskinetic activity of cabergoline, CI-1041, and Ro 61-8048 in MPTP monkeys with levodopa-induced dyskinesias.
Journal: Journal of molecular neuroscience : MN 20090601
Title: GSTpi expression in MPTP-induced dopaminergic neurodegeneration of C57BL/6 mouse midbrain and striatum.
Journal: Journal of molecular neuroscience : MN 20090601
Title: Interactions between cortical rhythms and spiking activity of single basal ganglia neurons in the normal and parkinsonian state.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20090601
Title: Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors.
Journal: European journal of medicinal chemistry 20090601
Title: Decreased inflammation and augmented expression of trophic factors correlate with MOG-induced neuroprotection of the injured nigrostriatal system in the murine MPTP model of Parkinson's disease.
Journal: International immunopharmacology 20090601
Title: MPTP-induced model of Parkinson's disease in cytochrome P450 2E1 knockout mice.
Journal: Neuropharmacology 20090601
Title: MPTP intoxication in mice: a useful model of Leigh syndrome to study mitochondrial diseases in childhood.
Journal: Metabolic brain disease 20090601
Title: Blockade of the translocation and activation of c-Jun N-terminal kinase 3 (JNK3) attenuates dopaminergic neuronal damage in mouse model of Parkinson's disease.
Journal: Neurochemistry international 20090601
Title: Copper reduces striatal protein nitration and tyrosine hydroxylase inactivation induced by MPP+ in rats.
Journal: Neurochemistry international 20090601
Title: Activation of p38 MAPK in the substantia nigra leads to nuclear translocation of NF-kappaB in MPTP-treated mice: implication in Parkinson's disease.
Journal: Journal of neurochemistry 20090601
Title: Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and alpha-synuclein inclusions.
Journal: Journal of neurochemistry 20090601
Title: Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases.
Journal: Journal of neurochemistry 20090601
Title: WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Journal: The European journal of neuroscience 20090601
Title: Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
Journal: PLoS genetics 20090601
Title: The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.
Journal: Rejuvenation research 20090601
Title: Neurogenesis in Neurotoxin-induced Animal Models for Parkinson's Disease-A Review of the Current Status.
Journal: Journal of toxicologic pathology 20090601
Title: Effect of estradiol on striatal dopamine activity of female hemiparkinsonian monkeys.
Journal: Journal of neuroscience research 20090515
Title: Strain-specific sensitivity to MPTP of C57BL/6 and BALB/c mice is age dependent.
Journal: Neuroreport 20090506
Title: Does melatonin help save dopaminergic cells in MPTP-treated mice?
Journal: Parkinsonism & related disorders 20090501
Title: Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys.
Journal: Journal of neurochemistry 20090501
Title: Functional effects of AAV2-GDNF on the dopaminergic nigrostriatal pathway in parkinsonian rhesus monkeys.
Journal: Human gene therapy 20090501
Title: Zocor Forte (simvastatin) has a neuroprotective effect against LPS striatal dopaminergic terminals injury, whereas against MPP+ does not.
Journal: European journal of pharmacology 20090501
Title: In vitro dopaminergic neuroprotective and in vivo antiparkinsonian-like effects of Delta 3,2-hydroxybakuchiol isolated from Psoralea corylifolia (L.).
Journal: Cellular and molecular life sciences : CMLS 20090501
Title: Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation.
Journal: Neurotoxicity research 20090501
Title: Zonisamide increases dopamine turnover in the striatum of mice and common marmosets treated with MPTP.
Journal: Journal of pharmacological sciences 20090501
Title: Mitochondria and energetic depression in cell pathophysiology.
Journal: International journal of molecular sciences 20090501
Title: High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease.
Journal: Neurology 20090421
Title: Antagonism of haloperidol-induced swim impairment in L-dopa and caffeine treated mice: a pre-clinical model to study Parkinson's disease.
Journal: Journal of neuroscience methods 20090415
Title: Protective actions of the vesicular monoamine transporter 2 (VMAT2) in monoaminergic neurons.
Journal: Molecular neurobiology 20090401
Title: Microglial activation is inhibited by corticosterone in dopaminergic neurodegeneration.
Journal: Journal of neuroimmunology 20090331
Title: Age- and sex-differences in the nitric oxide synthase expression and dopamine concentration in the murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Brain research 20090319
Title: Systemic lipopolysaccharide plus MPTP as a model of dopamine loss and gait instability in C57Bl/6J mice.
Journal: Behavioural brain research 20090317
Title: Quantitative evaluation of MPTP-treated nonhuman parkinsonian primates in the HALLWAY task.
Journal: Journal of neuroscience methods 20090315
Title: Combined kinase inhibition modulates parkin inactivation.
Journal: Human molecular genetics 20090301
Title: Identification of zebrafish A2 adenosine receptors and expression in developing embryos.
Journal: Gene expression patterns : GEP 20090301
Title: PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease.
Journal: The European journal of neuroscience 20090301
Title: Granulocyte-macrophage colony-stimulating factor promotes survival of dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced murine Parkinson's disease model.
Journal: The European journal of neuroscience 20090301
Title: Bone marrow-derived mesenchymal stem cell therapy as a candidate disease-modifying strategy in Parkinson's disease and multiple system atrophy.
Journal: Journal of clinical neurology (Seoul, Korea) 20090301
Title: Effect of a prolyl endopeptidase inhibitor benzyloxycarbonyl-alanyl-proline on the development of experimental depressive syndrome in rats.
Journal: Bulletin of experimental biology and medicine 20090301
Title: Targeting the progression of Parkinson's disease.
Journal: Current neuropharmacology 20090301
Title: Protective effect against Parkinson's disease-related insults through the activation of XBP1.
Journal: Brain research 20090227
Title: Objective quantification of arm rigidity in MPTP-treated primates.
Journal: Journal of neuroscience methods 20090215
Title: Beneficial effects of pioglitazone on cognitive impairment in MPTP model of Parkinson's disease.
Journal: Behavioural brain research 20090211
Title: Dopamine innervation in the thalamus: monkey versus rat.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20090201
Title: The effects of piroxicam in the attenuation of MPP+/MPTP toxicity in vitro and in vivo.
Journal: Neurochemical research 20090201
Title: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure fails to produce delayed degeneration of substantia nigra neurons in monkeys.
Journal: Journal of neuroscience research 20090201
Title: Dopaminergic denervation and spine loss in the striatum of MPTP-treated monkeys.
Journal: Experimental neurology 20090201
Title: Role of nuclear transcription factor kappa B (NF-kappaB) for MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine)-induced apoptosis in nigral neurons of mice.
Journal: Experimental and molecular pathology 20090201
Title: MPTP and MPP+ target specific aminergic cell populations in larval zebrafish.
Journal: Journal of neurochemistry 20090201
Title: Ghrelin antagonized 1-methyl-4-phenylpyridinium (MPP(+))-induced apoptosis in MES23.5 cells.
Journal: Journal of molecular neuroscience : MN 20090201
Title: Neurochemical plasticity in the enteric nervous system of a primate animal model of experimental Parkinsonism.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20090201
Title: The neurophysiology and effect of deep brain stimulation in a patient with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism.
Journal: Journal of neurosurgery 20090201
Title: Quantitative approach for incorporating methylmercury risks and omega-3 fatty acid benefits in developing species-specific fish consumption advice.
Journal: Environmental health perspectives 20090201
Title: Pyrethroid and organophosphate insecticide exposure in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease: an immunohistochemical analysis of tyrosine hydroxylase and glial fibrillary acidic protein in dorsolateral striatum.
Journal: Toxicology and industrial health 20090201
Title: Assessment of symptomatic and neuroprotective efficacy of Mucuna pruriens seed extract in rodent model of Parkinson's disease.
Journal: Neurotoxicity research 20090201
Title: [Effects of SV heat-resisting protein on the microglial cells in MPTP-treated mice].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20090201
Title: [The effect of TSPG in vivo on transplantation of neural stem cells in treatment of Parkinson's disease mouse].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20090201
Title: Potential mechanisms of neuroprotection induced by low dose total-body gamma-irradiation in C57 mice administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Journal: Neuroscience letters 20090130
Title: Acupuncture inhibits ferric iron deposition and ferritin-heavy chain reduction in an MPTP-induced parkinsonism model.
Journal: Neuroscience letters 20090130
Title: Neuroprotective effects of (+/-)-catechin against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity in mice.
Journal: Neuroscience letters 20090130
Title: Effects of endurance exercise on ventral tegmental area neurons in the chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and probenecid-treated mice.
Journal: Neuroscience letters 20090130
Title: Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.
Journal: The Journal of clinical investigation 20090105
Title: Oxidative and inflammatory pathways in Parkinson's disease.
Journal: Neurochemical research 20090101
Title: Modulation of neurotoxicant-induced increases in intracellular calcium by phytoestrogens differ for amyloid beta peptide (Abeta) and 1-methyl-4-phenyl-pyridine (MPP(+)).
Journal: Journal of applied toxicology : JAT 20090101
Title: Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nitric-oxide synthase 2 expression in astrocytes by a novel diindolylmethane analog protects striatal neurons against apoptosis.
Journal: Molecular pharmacology 20090101
Title: Alpha1-adrenoceptors mediate dihydroxyphenylalanine-induced activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaques.
Journal: The Journal of pharmacology and experimental therapeutics 20090101
Title: Enhanced susceptibility to MPTP neurotoxicity in magnesium-deficient C57BL/6N mice.
Journal: Neuroscience research 20090101
Title: Rg1 reduces nigral iron levels of MPTP-treated C57BL6 mice by regulating certain iron transport proteins.
Journal: Neurochemistry international 20090101
Title: Involvement of ubiquitin proteasome system in protective mechanisms of Puerarin to MPP(+)-elicited apoptosis.
Journal: Neuroscience research 20090101
Title: Transplantation of embryonic stem cell-derived dopaminergic neurons in MPTP-treated monkeys.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) does not elicit long-lasting increases in cyclooxygenase-2 expression in dopaminergic neurons of monkeys.
Journal: Journal of neuropathology and experimental neurology 20090101
Title: Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration.
Journal: BMC neuroscience 20090101
Title: Meeting report: consensus statement-Parkinson's disease and the environment: collaborative on health and the environment and Parkinson's Action Network (CHE PAN) conference 26-28 June 2007.
Journal: Environmental health perspectives 20090101
Title: Evolution of neurotoxins: from research modalities to clinical realities.
Journal: Current protocols in neuroscience 20090101
Title: [Effect of phosphorylated-ERK1/2 on inducible nitric oxide synthase expression in the substantia nigra of mice with MPTP-induced Parkinson disease].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090101
Title: PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease.
Journal: PloS one 20090101
Title: Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains.
Journal: Molecular neurodegeneration 20090101
Title: Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells.
Journal: PloS one 20090101
Title: Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain.
Journal: Journal of neuroinflammation 20090101
Title: [No-dependent modulation of the sensitivity of the mitochondrial permeability transition pore opening under ischemia-reperfusion of the isolated heart].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090101
Title: FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4.
Journal: PloS one 20090101
Title: Axonal degeneration of nigra-striatum dopaminergic neurons induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Journal: The Journal of international medical research 20090101
Title: Striatal neuroinflammation promotes Parkinsonism in rats.
Journal: PloS one 20090101
Title: Involvment of cytosolic and mitochondrial GSK-3beta in mitochondrial dysfunction and neuronal cell death of MPTP/MPP-treated neurons.
Journal: PloS one 20090101
Title: Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.
Journal: PloS one 20090101
Title: Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle.
Journal: Molecular neurodegeneration 20090101
Title: Cellular immune response to intrastriatally implanted allogeneic bone marrow stromal cells in a rat model of Parkinson's disease.
Journal: Journal of neuroinflammation 20090101
Title: Primate adult brain cell autotransplantation, a pilot study in asymptomatic MPTP-treated monkeys.
Journal: Cell transplantation 20090101
Title: Effects of prolylendopeptidase inhibitor benzyloxycarbonyl-methionyl-2(S)-cyanopyrrolidine on experimental depressive syndrome development in rats.
Journal: Bulletin of experimental biology and medicine 20090101
Title: Postulated vasoactive neuropeptide immunopathology affecting the blood-brain/blood-spinal barrier in certain neuropsychiatric fatigue-related conditions: A role for phosphodiesterase inhibitors in treatment?
Journal: Neuropsychiatric disease and treatment 20090101
Title: Evidence for oxidative stress in the developing cerebellum of the rat after chronic mild carbon monoxide exposure (0.0025% in air).
Journal: BMC neuroscience 20090101
Title: Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons.
Journal: Molecular neurodegeneration 20090101
Title: Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice.
Journal: Journal of neuroinflammation 20090101
Title: Paraquat induces oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats: neuroprotection and amelioration of symptoms by water-soluble formulation of coenzyme Q10.
Journal: BMC neuroscience 20090101
Title: Differential response of C57BL/6J mouse and DBA/2J mouse to optic nerve crush.
Journal: BMC neuroscience 20090101
Title: Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial.
Journal: Nutrition & metabolism 20090101
Title: Activation of mGlu3 receptors stimulates the production of GDNF in striatal neurons.
Journal: PloS one 20090101
Title: Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease.
Journal: BMC neuroscience 20090101
Title: Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101
Title: Enrichment from birth accelerates the functional and cellular development of a motor control area in the mouse.
Journal: PloS one 20090101
Title: Oxidative inactivation of mitochondrial aconitase results in iron and H2O2-mediated neurotoxicity in rat primary mesencephalic cultures.
Journal: PloS one 20090101
Title: Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Journal: PloS one 20090101
Title: [Dynamics of spectral parameters of the rat brain electrical activity in the model of depressive pain syndrome].
Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20090101
Title: NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures.
Journal: Molecular brain 20090101
Title: Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release.
Journal: ASN neuro 20090101
Title: Does neuroinflammation fan the flame in neurodegenerative diseases?
Journal: Molecular neurodegeneration 20090101
Title: The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity.
Journal: PloS one 20090101
Title: Dissociable effects of dopamine on neuronal firing rate and synchrony in the dorsal striatum.
Journal: Frontiers in integrative neuroscience 20090101
Title: Spatial distribution of Parkinson's disease mortality in Spain, 1989-1998, as a guide for focused aetiological research or health-care intervention.
Journal: BMC public health 20090101
Title: Coenzyme Q10 effects in neurodegenerative disease.
Journal: Neuropsychiatric disease and treatment 20090101
Title: Effects of chronic low dose rotenone treatment on human microglial cells.
Journal: Molecular neurodegeneration 20090101
Title: Copper sulfate prevents tyrosine hydroxylase reduced activity and motor deficits in a Parkinson's disease model in mice.
Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20090101
Title: The neurobiology of the substantia nigra pars compacta: from motor to sleep regulation.
Journal: Journal of neural transmission. Supplementum 20090101
Title: Distinct effects of intranigral L-DOPA infusion in the MPTP rat model of Parkinson's disease.
Journal: Journal of neural transmission. Supplementum 20090101
Title: Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson's disease.
Journal: Frontiers in aging neuroscience 20090101
Title: Biotelemetric monitoring of brain neurochemistry in conscious rats using microsensors and biosensors.
Journal: Sensors (Basel, Switzerland) 20090101
Title: Damage to the nigrostriatal system in the MPTP-treated SAMP8 mouse.
Journal: Neuroscience letters 20081226
Title: Effects of estrogens on striatal damage after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in male and female mice.
Journal: Molecular and cellular endocrinology 20081216
Title: A novel adenosine A(1) and A(2A) receptor antagonist ASP5854 ameliorates motor impairment in MPTP-treated marmosets: comparison with existing anti-Parkinson's disease drugs.
Journal: Behavioural brain research 20081212
Title: Effects of acute administration of the hydroalcoholic extract of mate tea leaves (Ilex paraguariensis) in animal models of learning and memory.
Journal: Journal of ethnopharmacology 20081208
Title: Biperiden enhances L-DOPA methyl ester and dopamine D(l) receptor agonist SKF-82958 but antagonizes D(2)/D(3) receptor agonist rotigotine antihemiparkinsonian actions.
Journal: European journal of pharmacology 20081203
Title: Adenosine A(2A) receptors in Parkinson's disease treatment.
Journal: Purinergic signalling 20081201
Title: Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment.
Journal: Neuropharmacology 20081201
Title: Balance of increases and decreases in firing rate of the spontaneous activity of basal ganglia high-frequency discharge neurons.
Journal: Journal of neurophysiology 20081201
Title: Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia.
Journal: Brain : a journal of neurology 20081201
Title: The effect of alpha-synuclein knockdown on MPP+ toxicity in models of human neurons.
Journal: The European journal of neuroscience 20081201
Title: Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze?
Journal: Neurotoxicity research 20081201
Title: Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance.
Journal: Annals of the New York Academy of Sciences 20081201
Title: Functional models of Parkinson's disease: a valuable tool in the development of novel therapies.
Journal: Annals of neurology 20081201
Title: Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR alpha1, gene.
Journal: Brain research 20081119
Title: Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081119
Title: The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains.
Journal: Journal of neuroimmunology 20081115
Title: Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20081115
Title: Striatal 19S Rpt6 deficit is related to alpha-synuclein accumulation in MPTP-treated mice.
Journal: Biochemical and biophysical research communications 20081114
Title: Proteasome inhibitor does not enhance MPTP neurotoxicity in mice.
Journal: Cellular and molecular neurobiology 20081101
Title: Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081101
Title: Neural progenitor cells are protected against MPTP by MAO-B inhibitors.
Journal: Neurotoxicology 20081101
Title: Molecular imaging reveals a correlation between 2'-CH3-MPTP-induced neonatal neurotoxicity and dopaminergic neurodegeneration in adult transgenic mice.
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20081101
Title: Memory, mood, dopamine, and serotonin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury.
Journal: Neurobiology of disease 20081101
Title: Modelling Parkinson-like neurodegeneration via osmotic minipump delivery of MPTP and probenecid.
Journal: Journal of neurochemistry 20081101
Title: Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation.
Journal: Journal of neurophysiology 20081101
Title: Deep brain stimulation reduces neuronal entropy in the MPTP-primate model of Parkinson's disease.
Journal: Journal of neurophysiology 20081101
Title: Proteomic analysis of the neuroprotective mechanisms of acupuncture treatment in a Parkinson's disease mouse model.
Journal: Proteomics 20081101
Title: A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.
Journal: PLoS genetics 20081101
Title: Therapeutic modulation of apoptosis: targeting the BCL-2 family at the interface of the mitochondrial membrane.
Journal: Yonsei medical journal 20081031
Title: Sensitive and selective liquid chromatography/tandem mass spectrometry methods for quantitative analysis of 1-methyl-4-phenyl pyridinium (MPP+) in mouse striatal tissue.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081015
Title: Effects of levodopa on striatal monoamines in mice with levodopa-induced hyperactivity.
Journal: Neuroscience letters 20081010
Title: Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats.
Journal: European journal of pharmacology 20081010
Title: A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model.
Journal: Pharmacology, biochemistry, and behavior 20081001
Title: A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice.
Journal: Neuropharmacology 20081001
Title: Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.
Journal: Bioorganic & medicinal chemistry 20081001
Title: Parkinson disease: primacy of age as a risk factor for mitochondrial dysfunction.
Journal: Metabolism: clinical and experimental 20081001
Title: Targeting reactive oxygen species, reactive nitrogen species and inflammation in MPTP neurotoxicity and Parkinson's disease.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20081001
Title: Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: protective role of S-allylcysteine.
Journal: Free radical research 20081001
Title: Defining 'neuroinflammation'.
Journal: Annals of the New York Academy of Sciences 20081001
Title: Extranigral neurodegeneration in Parkinson's disease.
Journal: Annals of the New York Academy of Sciences 20081001
Title: Methamphetamine fails to alter the noradrenergic integrity of the heart.
Journal: Annals of the New York Academy of Sciences 20081001
Title: MPTP- but not methamphetamine-induced parkinsonism extends to catecholamine neurons in the gut.
Journal: Annals of the New York Academy of Sciences 20081001
Title: Behavioral recovery in MPTP-treated monkeys: neurochemical mechanisms studied by intrastriatal microdialysis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080917
Title: The tert-butoxyl radical mediated hydrogen atom transfer reactions of the Parkinsonian proneurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and selected tertiary amines.
Journal: Bioorganic & medicinal chemistry 20080915
Title: Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum.
Journal: Neuroscience 20080909
Title: Dopamine transporter inhibitory and antiparkinsonian effect of common flowering quince extract.
Journal: Pharmacology, biochemistry, and behavior 20080901
Title: Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment.
Journal: Journal of neuroscience research 20080901
Title: Endogenous dopamine suppresses initiation of swimming in prefeeding zebrafish larvae.
Journal: Journal of neurophysiology 20080901
Title: Developmental heptachlor exposure increases susceptibility of dopamine neurons to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)in a gender-specific manner.
Journal: Neurotoxicology 20080901
Title: Amiloride is neuroprotective in an MPTP model of Parkinson's disease.
Journal: Neurobiology of disease 20080901
Title: Comparative pharmacological study of free radical scavenger, nitric oxide synthase inhibitor, nitric oxide synthase activator and cyclooxygenase inhibitor against MPTP neurotoxicity in mice.
Journal: Metabolic brain disease 20080901
Title: Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatum.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901
Title: Effects of sildenafil on nigrostriatal dopamine neurons in a murine model of Parkinson's disease.
Journal: Journal of Alzheimer's disease : JAD 20080901
Title: Neuroprotective effect of benzylideneacetophenone derivative on the MPTP model of neurodegeneration in mice.
Journal: Archives of pharmacal research 20080901
Title: Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans.
Journal: Current neuropharmacology 20080901
Title: Melatonin combats molecular terrorism at the mitochondrial level.
Journal: Interdisciplinary toxicology 20080901
Title: Neuroprotective effects of resveratrol on MPTP-induced neuron loss mediated by free radical scavenging.
Journal: Journal of agricultural and food chemistry 20080827
Title: Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys.
Journal: Glia 20080815
Title: Neuroprotective effect of baicalein against MPTP neurotoxicity: behavioral, biochemical and immunohistochemical profile.
Journal: Neuroscience letters 20080815
Title: Estrogen and SERM neuroprotection in animal models of Parkinson's disease.
Journal: Molecular and cellular endocrinology 20080813
Title: Acrylamide: a dietary carcinogen formed in vivo?
Journal: Journal of agricultural and food chemistry 20080813
Title: Hypersensitivity of aquaporin 4-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine and astrocytic modulation.
Journal: Neurobiology of aging 20080801
Title: Taurine fails to protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion in mice.
Journal: Amino acids 20080801
Title: Development of a stable, early stage unilateral model of Parkinson's disease in middle-aged rhesus monkeys.
Journal: Experimental neurology 20080801
Title: Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra.
Journal: Experimental neurology 20080801
Title: Pathologic modifications of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated squirrel monkeys.
Journal: Journal of neuropathology and experimental neurology 20080801
Title: Broad neuroprotective profile of nicotinamide in different mouse models of MPTP-induced parkinsonism.
Journal: The European journal of neuroscience 20080801
Title: Significant effect of dimethylsulfoniopropionate on Parkinson's disease of senescence-accelerated mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Journal of nutritional science and vitaminology 20080801
Title: [Ginsenoside Rg1 modulates COX-2 expression in the substantia nigra of mice with MPTP-induced Parkinson disease through the P38 signaling pathway].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801
Title: Inversion of dopamine responses in striatal medium spiny neurons and involuntary movements.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080723
Title: mGluR5 metabotropic glutamate receptors and dyskinesias in MPTP monkeys.
Journal: Neurobiology of aging 20080701
Title: Role of protein kinase Cdelta in paraquat-induced glial cell death.
Journal: Journal of neuroscience research 20080701
Title: PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080701
Title: Methamphetamine-induced neurotoxicity and microglial activation are not mediated by fractalkine receptor signaling.
Journal: Journal of neurochemistry 20080701
Title: Striatal histone modifications in models of levodopa-induced dyskinesia.
Journal: Journal of neurochemistry 20080701
Title: Neuroprotective activities of catalpol on MPP+/MPTP-induced neurotoxicity.
Journal: Neurological research 20080701
Title: Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080701
Title: Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease.
Journal: Brain : a journal of neurology 20080701
Title: Electrochemical mass spectrometric studies on 1-cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Rapid communications in mass spectrometry : RCM 20080701
Title: Parkinson's disease and the gut: a well known clinical association in need of an effective cure and explanation.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080701
Title: Relationship between the severity of hypokinesia induced by neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and neurochemical changes in brain structures of C57Bl/6 mice.
Journal: Bulletin of experimental biology and medicine 20080701
Title: Protective effects of SUN N8075, a novel agent with antioxidant properties, in in vitro and in vivo models of Parkinson's disease.
Journal: Brain research 20080612
Title: Globus pallidus plays a critical role in neurotrophic factor induced functional improvements in hemiparkinsonian monkeys.
Journal: Biochemical and biophysical research communications 20080606
Title: Hemiparkinsonian rats rotate toward the side with the weaker dopaminergic neurotransmission.
Journal: Behavioural brain research 20080603
Title: Role of lipoamide dehydrogenase and metallothionein on 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity.
Journal: Neurochemical research 20080601
Title: Role of reactive nitrogen and reactive oxygen species against MPTP neurotoxicity in mice.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080601
Title: Pre-synaptic dopaminergic compensation after moderate nigrostriatal damage in non-human primates.
Journal: Journal of neurochemistry 20080601
Title: Role of tuberin in neuronal degeneration.
Journal: Neurochemical research 20080601
Title: Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease.
Journal: Free radical biology & medicine 20080601
Title: Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.
Journal: Experimental neurology 20080601
Title: Failure of acute administration with proteasome inhibitor to provide a model of Parkinson's disease in mice.
Journal: Metabolic brain disease 20080601
Title: Neuroprotective effects of PACAP27 in mice model of Parkinson's disease involved in the modulation of K(ATP) subunits and D2 receptors in the striatum.
Journal: Neuropeptides 20080601
Title: Role of homocysteine in the treatment of Parkinson's disease.
Journal: Expert review of neurotherapeutics 20080601
Title: Expression of Cbl-interacting protein of 85 kDa in MPTP mouse model of Parkinson's disease and 1-methyl-4-phenyl-pyridinium ion-treated dopaminergic SH-SY5Y cells.
Journal: Acta biochimica et biophysica Sinica 20080601
Title: Calpain as a potential therapeutic target in Parkinson's disease.
Journal: CNS & neurological disorders drug targets 20080601
Title: Fibroblast growth factor 2 enhances striatal and nigral neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal: Neuroscience 20080515
Title: Alteration of dopaminergic markers in gastrointestinal tract of different rodent models of Parkinson's disease.
Journal: Neuroscience 20080515
Title: Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.
Journal: Neurochemical research 20080501
Title: Comparison of the time courses of selective gene expression and dopaminergic depletion induced by MPP+ in MN9D cells.
Journal: Neurochemistry international 20080501
Title: Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080501
Title: In vitro and in vivo evidences that antioxidant action contributes to the neuroprotective effects of the neuronal nitric oxide synthase and monoamine oxidase-B inhibitor, 7-nitroindazole.
Journal: Neurochemistry international 20080501
Title: Delayed treatment with arundic acid reduces the MPTP-induced neurotoxicity in mice.
Journal: Cellular and molecular neurobiology 20080501
Title: Cotinine selectively activates a subpopulation of alpha3/alpha6beta2 nicotinic receptors in monkey striatum.
Journal: The Journal of pharmacology and experimental therapeutics 20080501
Title: Attenuation of MPTP neurotoxicity by rolipram, a specific inhibitor of phosphodiesterase IV.
Journal: Experimental neurology 20080501
Title: The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B.
Journal: British journal of pharmacology 20080501
Title: Pallidal burst activity during therapeutic deep brain stimulation.
Journal: Experimental neurology 20080501
Title: Nicotine and caffeine-mediated modulation in the expression of toxicant responsive genes and vesicular monoamine transporter-2 in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype in mouse.
Journal: Brain research 20080501
Title: Neurotoxicity of MPTP to migrating neuroblasts: studies in acute and subacute mouse models of Parkinson's disease.
Journal: Neurotoxicology 20080501
Title: Involvement of brain dopaminergic systems in the development of an MPTP-induced depressive state in rats.
Journal: Neuroscience and behavioral physiology 20080501
Title: Quantitative gene expression profiling of mouse brain regions reveals differential transcripts conserved in human and affected in disease models.
Journal: Physiological genomics 20080422
Title: Differential effects of overexpression of wild-type and mutant human alpha-synuclein on MPP+-induced neurotoxicity in PC12 cells.
Journal: Neuroscience letters 20080418
Title: Transplantation of human amniotic cells exerts neuroprotection in MPTP-induced Parkinson disease mice.
Journal: Brain research 20080418
Title: The novel cyclooxygenase-2 inhibitor GW637185X protects against l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
Journal: Neuroreport 20080416
Title: Lesion of the centromedian thalamic nucleus in MPTP-treated monkeys.
Journal: Movement disorders : official journal of the Movement Disorder Society 20080415
Title: Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080401
Title: MPTP-treated mice: long-lasting loss of nigral TH-ir neurons but not paradoxical sleep alterations.
Journal: Experimental brain research 20080401
Title: Effect of (R)-salsolinol and N-methyl-(R)-salsolinol on the balance impairment between dopamine and acetylcholine in rat brain: involvement in pathogenesis of Parkinson disease.
Journal: Clinical chemistry 20080401
Title: The role of MPTP in Parkinson's disease: connecting brain and gut?
Journal: Experimental neurology 20080401
Title: Stereochemical studies on the novel monoamine oxidase B substrates (1R,6S)- and (1S,6R)-3-methyl-6-phenyl-3-aza-bicyclo[4.1.0]heptane.
Journal: Bioorganic & medicinal chemistry 20080401
Title: [Responsive changes to MPTP in rats with DAT inhibited by antisense oligonucleotides].
Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20080401
Title: Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice.
Journal: Inflammopharmacology 20080401
Title: Inhibition of the outgrowth and elongation of neurites from pheochromocytoma cells by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and preventive effects of dimethylsulfoniopropionate in the presence of nerve growth factor.
Journal: Journal of nutritional science and vitaminology 20080401
Title: [Isolation and identification of Suavissimoside R1 from roots of Rubus parvifollus used for protecting dopaminergic neurons against MPP+ toxicity].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080401
Title: Neuropathological changes induced by neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in male Swiss albino mice.
Journal: Toxicology and industrial health 20080401
Title: Glycyrrhizin Attenuates MPTP Neurotoxicity in Mouse and MPP-Induced Cell Death in PC12 Cells.
Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20080401
Title: Role of glial cell derived neurotrophic factor in the protective effect of smilagenin on rat mesencephalic dopaminergic neurons damaged by MPP+.
Journal: FEBS letters 20080319
Title: Glial reactions in Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20080315
Title: Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?
Journal: Genes, brain, and behavior 20080301
Title: Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism.
Journal: Journal of neurochemistry 20080301
Title: Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson's disease.
Journal: Metabolic brain disease 20080301
Title: Spinal cord degeneration in C57BL/6N mice following induction of experimental parkinsonism with MPTP.
Journal: Journal of neurochemistry 20080301
Title: Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice.
Journal: Experimental neurology 20080301
Title: Loss of aromatase cytochrome P450 function as a risk factor for Parkinson's disease?
Journal: Brain research reviews 20080301
Title: Structure-activity relationships in the inhibition of monoamine oxidase B by 1-methyl-3-phenylpyrroles.
Journal: Bioorganic & medicinal chemistry 20080301
Title: Thalamocortical relay fidelity varies across subthalamic nucleus deep brain stimulation protocols in a data-driven computational model.
Journal: Journal of neurophysiology 20080301
Title: Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease.
Journal: Biochimica et biophysica acta 20080301
Title: Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms.
Journal: Annals of neurology 20080301
Title: Forebrain dopamine depletion impairs motor behavior in lamprey.
Journal: The European journal of neuroscience 20080301
Title: Proteome analysis of ventral midbrain in MPTP-treated normal and L1cam transgenic mice.
Journal: Proteomics 20080301
Title: Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery.
Journal: The AAPS journal 20080301
Title: [Protective effects of Cistanche total glycosides on dopaminergic neuron in substantia nigra of model mice of Parkinson's disease].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080301
Title: Vesicular monoamine transporter substrate/inhibitor activity of MPTP/MPP+ derivatives: a structure-activity study.
Journal: Journal of medicinal chemistry 20080227
Title: Systemic proteasomal inhibitor exposure enhances dopamine turnover and decreases dopamine levels but does not affect MPTP-induced striatal dopamine depletion in mice.
Journal: Synapse (New York, N.Y.) 20080201
Title: Normalization of GABAA receptor specific binding in the substantia nigra reticulata and the prevention of L-dopa-induced dyskinesias in MPTP parkinsonian monkeys.
Journal: Synapse (New York, N.Y.) 20080201
Title: Membrane-permeable Bcl-xL prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra.
Journal: Journal of neurochemistry 20080201
Title: Basal ganglia group II metabotropic glutamate receptors specific binding in non-human primate model of L-Dopa-induced dyskinesias.
Journal: Neuropharmacology 20080201
Title: S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiological and behavioral characterization in vivo.
Journal: The Journal of pharmacology and experimental therapeutics 20080201
Title: Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease.
Journal: Neuroscience research 20080201
Title: Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity.
Journal: Annals of neurology 20080201
Title: Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish.
Journal: Developmental biology 20080201
Title: Mitochondrial dysfunction, oxidative stress, and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease.
Journal: Journal of proteome research 20080201
Title: [Evaluation of motor disorders in animal models of Parkinson's disease].
Journal: Revista de neurologia 20080201
Title: Antiparkinsonian effect of nerve growth factor adsorbed on polybutylcyanoacrylate nanoparticles coated with polysorbate-80.
Journal: Bulletin of experimental biology and medicine 20080201
Title: Repeated intranigral MPTP administration: a new protocol of prolonged locomotor impairment mimicking Parkinson's disease.
Journal: Journal of neuroscience methods 20080130
Title: Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys.
Journal: Behavioural brain research 20080125
Title: Exploring the neuroprotective effects of modafinil in a marmoset Parkinson model with immunohistochemistry, magnetic resonance imaging and spectroscopy.
Journal: Brain research 20080116
Title: Low-pass filter properties of basal ganglia cortical muscle loops in the normal and MPTP primate model of parkinsonism.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080116
Title: A cell-permeable peptide inhibitor TAT-JBD reduces the MPP+-induced caspase-9 activation but does not prevent the dopaminergic degeneration in substantia nigra of rats.
Journal: Toxicology 20080114
Title: Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080109
Title: Estimation of D2-like receptor occupancy by dopamine in the putamen of hemiparkinsonian Monkeys.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080101
Title: MPTP-induced deficits in striatal synaptic plasticity are prevented by glial cell line-derived neurotrophic factor expressed via an adeno-associated viral vector.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080101
Title: L-Dopa treatment abolishes the numerical increase in striatal dopaminergic neurons in parkinsonian monkeys.
Journal: Journal of chemical neuroanatomy 20080101
Title: Neurobehavioral protection by single dose l-deprenyl against MPTP-induced parkinsonism in common marmosets.
Journal: Psychopharmacology 20080101
Title: Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson's disease.
Journal: Neurobiology of disease 20080101
Title: Bak Foong protects dopaminergic neurons against MPTP-induced neurotoxicity by its anti-apoptotic activity.
Journal: Cell biology international 20080101
Title: Effects of low-frequency stimulation of the subthalamic nucleus on movement in Parkinson's disease.
Journal: Experimental neurology 20080101
Title: Alteration in the differentiation-related molecular expression in the subventricular zone in a mouse model of Parkinson's disease.
Journal: Neuroscience research 20080101
Title: Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction.
Journal: The European journal of neuroscience 20080101
Title: Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.
Journal: PloS one 20080101
Title: Protection by the NDI1 gene against neurodegeneration in a rotenone rat model of Parkinson's disease.
Journal: PloS one 20080101
Title: Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure.
Journal: PloS one 20080101
Title: Proteome analysis of human substantia nigra in Parkinson's disease.
Journal: Proteome science 20080101
Title: MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology.
Journal: PloS one 20080101
Title: Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease.
Journal: Journal of neuroinflammation 20080101
Title: Effects of aging on neuroprotective and neurotoxic properties of microglia in neurodegenerative diseases.
Journal: Neuro-degenerative diseases 20080101
Title: Metabolic profiling reveals therapeutic effects of Herba Cistanches in an animal model of hydrocortisone-induced 'kidney-deficiency syndrome'.
Journal: Chinese medicine 20080101
Title: Genetic variability of histamine receptors in patients with Parkinson's disease.
Journal: BMC medical genetics 20080101
Title: [Use of 11C-(+)-alpha -dihydrotetrabenazine for the assessment of dopaminergic innervation in animal models of Parkinson's disease].
Journal: Revista espanola de medicina nuclear 20080101
Title: Calpain-mediated MPP+ toxicity in mitochondrial DNA depleted cells.
Journal: Neurotoxicity research 20080101
Title: Pesticide exposure and risk of Parkinson's disease: a family-based case-control study.
Journal: BMC neurology 20080101
Title: Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease.
Journal: BMC neuroscience 20080101
Title: Peroxisome Proliferator-Activated Receptor-gamma in Amyotrophic Lateral Sclerosis and Huntington's Disease.
Journal: PPAR research 20080101
Title: Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.
Journal: Journal of neuroinflammation 20080101
Title: Intraputamenal infusion of exogenous neurturin protein restores motor and dopaminergic function in the globus pallidus of MPTP-lesioned rhesus monkeys.
Journal: Cell transplantation 20080101
Title: GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys.
Journal: Cell transplantation 20080101
Title: Pharmacological MRI (phMRI) monitoring of treatment in hemiparkinsonian rhesus monkeys.
Journal: Cell transplantation 20080101
Title: PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.
Journal: PloS one 20080101
Title: Role of CYP2E1 in the mouse model of MPTP toxicity.
Journal: Parkinsonism & related disorders 20080101
Title: Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol.
Journal: Parkinsonism & related disorders 20080101
Title: Transgenic rodent models of Parkinson's disease.
Journal: Acta neurochirurgica. Supplement 20080101
Title: Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice.
Journal: PloS one 20080101
Title: PPAR Regulation of Inflammatory Signaling in CNS Diseases.
Journal: PPAR research 20080101
Title: Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons.
Journal: BMC neuroscience 20080101
Title: Expression of TLR4 and CD14 in the central nervous system (CNS) in a MPTP mouse model of Parkinson's-like disease.
Journal: Immunopharmacology and immunotoxicology 20080101
Title: Brain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementation.
Journal: Journal of the International Society of Sports Nutrition 20080101
Title: TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease.
Journal: Journal of neuroinflammation 20080101
Title: Potential developmental neurotoxicity of pesticides used in Europe.
Journal: Environmental health : a global access science source 20080101
Title: NADPH oxidase as a therapeutic target in Alzheimer's disease.
Journal: BMC neuroscience 20080101
Title: [Glutamate antibodies in the development of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonian syndrome in C57B1/6 mice].
Journal: Patologicheskaia fiziologiia i eksperimental'naia terapiia 20080101
Title: Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP+-induced oxidative stress.
Journal: Oxidative medicine and cellular longevity 20080101
Title: Therapeutic Potential of PPARγ Activation in Stroke.
Journal: PPAR research 20080101
Title: RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20071226
Title: [Changes of amino acids neurotransmitters in striatum of hemi-parkinsonian rhesus monkey after high frequency stimulation of subthalamic nucleus].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20071215
Title: Constitutive expression and functional characterization of mitochondrial glutaredoxin (Grx2) in mouse and human brain.
Journal: Brain research 20071214
Title: Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro.
Journal: Journal of molecular medicine (Berlin, Germany) 20071201
Title: The number of dopaminergic cells is increased in the olfactory bulb of monkeys chronically exposed to MPTP.
Journal: Synapse (New York, N.Y.) 20071201
Title: Pael receptor is involved in dopamine metabolism in the nigrostriatal system.
Journal: Neuroscience research 20071201
Title: Bone-marrow-derived cell differentiation into microglia: a study in a progressive mouse model of Parkinson's disease.
Journal: Neurobiology of disease 20071201
Title: The administration of entacapone prevents L-dopa-induced dyskinesia when added to dopamine agonist therapy in MPTP-treated primates.
Journal: Experimental neurology 20071201
Title: Nicotine reduces levodopa-induced dyskinesias in lesioned monkeys.
Journal: Annals of neurology 20071201
Title: Enhanced tyrosine hydroxylase expression in PC12 cells co-cultured with feline mesenchymal stem cells.
Journal: Journal of veterinary science 20071201
Title: Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions.
Journal: Current neuropharmacology 20071201
Title: The neuropharmacology of (-)-stepholidine and its potential applications.
Journal: Current neuropharmacology 20071201
Title: Proteome analysis of substantia nigra and striatal tissue in the mouse MPTP model of Parkinson's disease.
Journal: Proteomics. Clinical applications 20071201
Title: MPTP administration in mice changes the ratio of splice isoforms of fosB and rgs9.
Journal: Brain research 20071128
Title: Changes in the rates of the tricarboxylic acid (TCA) cycle and glutamine synthesis in the monkey brain with hemiparkinsonism induced by intracarotid infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): studies by non-invasive 13C-magnetic resonance spectroscopy.
Journal: Brain research 20071121
Title: Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease.
Journal: Journal of leukocyte biology 20071101
Title: Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats.
Journal: Experimental neurology 20071101
Title: Paraquat: the red herring of Parkinson's disease research.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071101
Title: [Protective effect of baicalin on mouse with Parkinson's disease induced by MPTP].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20071101
Title: [The protective effect of nicotine on dopaminergic neuron of Parkinson's disease mice].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20071101
Title: Complement 3-deficient mice are not protected against MPTP-induced dopaminergic neurotoxicity.
Journal: Brain research 20071031
Title: Increased host neuronal survival and motor function in BMT Parkinsonian mice: involvement of immunosuppression.
Journal: The Journal of comparative neurology 20071020
Title: Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta.
Journal: Brain research 20071017
Title: Quantitative [(123)I]FP-CIT pinhole SPECT imaging predicts striatal dopamine levels, but not number of nigral neurons in different mouse models of Parkinson's disease.
Journal: NeuroImage 20071015
Title: Endurance exercise promotes cardiorespiratory rehabilitation without neurorestoration in the chronic mouse model of parkinsonism with severe neurodegeneration.
Journal: Neuroscience 20071012
Title: Blockade of cannabinoid type 1 receptors augments the antiparkinsonian action of levodopa without affecting dyskinesias in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated rhesus monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20071001
Title: Non-motor behavioural impairments in parkin-deficient mice.
Journal: The European journal of neuroscience 20071001
Title: Prolonged toxicokinetics and toxicodynamics of paraquat in mouse brain.
Journal: Environmental health perspectives 20071001
Title: Neuroprotective effect of dipeptide AVP(4-5)-NH2 is associated with nerve growth factor and heat shock protein HSP70.
Journal: Bulletin of experimental biology and medicine 20071001
Title: Chronic exposure to low levels of aluminum alters cerebral cell signaling in response to acute MPTP administration.
Journal: Toxicology and industrial health 20071001
Title: Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20070904
Title: Gene expression profiling of MPP+-treated MN9D cells: a mechanism of toxicity study.
Journal: Neurotoxicology 20070901
Title: Toki-to protects dopaminergic neurons in the substantia nigra from neurotoxicity of MPTP in mice.
Journal: Phytotherapy research : PTR 20070901
Title: Rapid down-regulation of Ret following exposure of dopaminergic neurons to neurotoxins.
Journal: Journal of neurochemistry 20070901
Title: Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 20070901
Title: Loss of enteric dopaminergic neurons and associated changes in colon motility in an MPTP mouse model of Parkinson's disease.
Journal: Experimental neurology 20070901
Title: Exacerbation of dopaminergic terminal damage in a mouse model of Parkinson's disease by the G-protein-coupled receptor protease-activated receptor 1.
Journal: Molecular pharmacology 20070901
Title: Evaluation of neuroprotective and anti-fatigue effects of sildenafil.
Journal: Life sciences 20070901
Title: Aminochrome as a preclinical experimental model to study degeneration of dopaminergic neurons in Parkinson's disease.
Journal: Neurotoxicity research 20070901
Title: Brain-derived neurotrophic factor expression in the substantia nigra does not change after lesions of dopaminergic neurons.
Journal: Neurotoxicity research 20070901
Title: Adenosine A(1) receptor: Functional receptor-receptor interactions in the brain.
Journal: Purinergic signalling 20070901
Title: MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine.
Journal: Purinergic signalling 20070901
Title: Homocysteine is toxic for dopaminergic neurons in primary mesencephalic culture.
Journal: Neuroreport 20070827
Title: 17Beta-estradiol reduces nitrotyrosine immunoreactivity and increases SOD1 and SOD2 immunoreactivity in nigral neurons in male mice following MPTP insult.
Journal: Brain research 20070820
Title: A beam-walking apparatus to assess behavioural impairments in MPTP-treated mice: pharmacological validation with R-(-)-deprenyl.
Journal: Journal of neuroscience methods 20070815
Title: Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain.
Journal: Neuroscience 20070810
Title: The effects of serotoninergic, noradrenergic, cholinergic and dopaminergic drugs on vigilance states in MPTP-treated mice.
Journal: Brain research 20070803
Title: Interaction between nicotine and MPTP/MPP+ in rat brain endothelial cells.
Journal: Life sciences 20070802
Title: Effect of acute administration of hydroalcohol extract of Ilex paraguariensis St Hilaire (Aquifoliaceae) in animal models of Parkinson's disease.
Journal: Phytotherapy research : PTR 20070801
Title: Impaired mutagenic activities of MPDP(+) (1-methyl-4-phenyl-2,3-dihydropyridinium) and MPP(+) (1-methyl-4-phenylpyridinium) due to their interactions with methylxanthines.
Journal: Bioorganic & medicinal chemistry 20070801
Title: Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter.
Journal: Neurobiology of disease 20070801
Title: Survival of midbrain dopaminergic cells after lesion or deep brain stimulation of the subthalamic nucleus in MPTP-treated monkeys.
Journal: Brain : a journal of neurology 20070801
Title: In vivo evidence of D3 dopamine receptor sensitization in parkinsonian primates and rodents with l-DOPA-induced dyskinesias.
Journal: Neurobiology of disease 20070801
Title: Correlation between levels of pigment epithelium-derived factor and vascular endothelial growth factor in the striatum of patients with Parkinson's disease.
Journal: Experimental neurology 20070801
Title: The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070801
Title: Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease.
Journal: CNS & neurological disorders drug targets 20070801
Title: [Effect of phosphorylated c-Jun expression on COX-2 expression in the substantia nigra of MPTP mouse model of subacute Parkinson disease].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070801
Title: Microarray analysis of laser capture microdissected substantia nigra pars compacta after a single administration of MPTP in common marmosets.
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20070801
Title: Neurotoxicity studies with the monoamine oxidase B substrate 1-methyl-3-phenyl-3-pyrroline.
Journal: Life sciences 20070719
Title: Comparative analysis of the effects of resveratrol in two apoptotic models: inhibition of complex I and potassium deprivation in cerebellar neurons.
Journal: Neuroscience 20070713
Title: Unique responses to mitochondrial complex I inhibition in tuberoinfundibular dopamine neurons may impart resistance to toxic insult.
Journal: Neuroscience 20070713
Title: Neurotoxicity in murine striatal dopaminergic pathways following long-term application of low doses of permethrin and MPTP.
Journal: Toxicology letters 20070710
Title: SPECT imaging, immunohistochemical and behavioural correlations in the primate models of Parkinson's disease.
Journal: Parkinsonism & related disorders 20070701
Title: Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by alpha-lipoic acid.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701
Title: Apoptotic mode of cell death in substantia nigra following intranigral infusion of the parkinsonian neurotoxin, MPP+ in Sprague-Dawley rats: cellular, molecular and ultrastructural evidences.
Journal: Neurochemical research 20070701
Title: Nigrostriatal damage preferentially decreases a subpopulation of alpha6beta2* nAChRs in mouse, monkey, and Parkinson's disease striatum.
Journal: Molecular pharmacology 20070701
Title: Neuroprotective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) in MPP+-induced alteration of translational control in Neuro-2a neuroblastoma cells.
Journal: Journal of neuroscience research 20070701
Title: Lamotrigine is neuroprotective in the energy deficiency model of MPTP intoxicated mice.
Journal: Pediatric research 20070701
Title: Striatal leucine-rich repeat kinase 2 mRNA is increased in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned common marmosets (Callithrix jacchus) with L-3, 4-dihydroxyphenylalanine methyl ester-induced dyskinesia.
Journal: The European journal of neuroscience 20070701
Title: 'Rejuvenation' protects neurons in mouse models of Parkinson's disease.
Journal: Nature 20070628
Title: Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease.
Journal: European journal of pharmacology 20070614
Title: Localization and expression of group I metabotropic glutamate receptors in the mouse striatum, globus pallidus, and subthalamic nucleus: regulatory effects of MPTP treatment and constitutive Homer deletion.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070606
Title: Increased murine neonatal iron intake results in Parkinson-like neurodegeneration with age.
Journal: Neurobiology of aging 20070601
Title: Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson's disease.
Journal: Neurobiology of disease 20070601
Title: Non-steroidal anti-inflammatory drugs in Parkinson's disease.
Journal: Experimental neurology 20070601
Title: Activated microglia affect the nigro-striatal dopamine neurons differently in neonatal and aged mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Journal of neuroscience research 20070601
Title: Inhibition of glycogen synthase kinase-3beta protects dopaminergic neurons from MPTP toxicity.
Journal: Neuropharmacology 20070601
Title: Mitochondrial nutrition as a strategy for neuroprotection in Parkinson's disease—research focus in the department of alternative medicine and experimental therapeutics at Hokuriku University.
Journal: Evidence-based complementary and alternative medicine : eCAM 20070601
Title: Rasagiline - a novel MAO B inhibitor in Parkinson's disease therapy.
Journal: Therapeutics and clinical risk management 20070601
Title: Fluoro-Jade C can specifically stain the degenerative neurons in the substantia nigra of the 1-methyl-4-phenyl-1,2,3,6-tetrahydro pyridine-treated C57BL/6 mice.
Journal: Brain research 20070530
Title: Use-dependent behavioral and neurochemical asymmetry in MPTP mice.
Journal: Neuroscience letters 20070518
Title: Mangiferin protects against 1-methyl-4-phenylpyridinium toxicity mediated by oxidative stress in N2A cells.
Journal: Neuroscience letters 20070517
Title: Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070516
Title: Pre-training to find a hidden platform in the Morris water maze can compensate for a deficit to find a cued platform in a rat model of Parkinson's disease.
Journal: Neurobiology of learning and memory 20070501
Title: Does ORP150/HSP12A protect dopaminergic neurons against MPTP/MPP(+)-induced neurotoxicity?
Journal: Antioxidants & redox signaling 20070501
Title: The selective kappa-opioid receptor agonist U50,488 reduces L-dopa-induced dyskinesias but worsens parkinsonism in MPTP-treated primates.
Journal: Experimental neurology 20070501
Title: MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.
Journal: Neurobiology of disease 20070501
Title: A highly sensitive automated complex running wheel test to detect latent motor deficits in the mouse MPTP model of Parkinson's disease.
Journal: Experimental neurology 20070501
Title: Altered D(1) dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates.
Journal: Neurobiology of disease 20070501
Title: Modification of the number and phenotype of striatal dopaminergic cells by carotid body graft.
Journal: Brain : a journal of neurology 20070501
Title: Does thioredoxin-1 prevent mitochondria- and endoplasmic reticulum-mediated neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine?
Journal: Antioxidants & redox signaling 20070501
Title: N-methyltetrahydro-beta-carboline analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin are oxidized to neurotoxic beta-carbolinium cations by heme peroxidases.
Journal: Biochemical and biophysical research communications 20070427
Title: Antioxidant responses and lipid peroxidation following intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats: increased susceptibility of olfactory bulb.
Journal: Life sciences 20070424
Title: An orally active catalytic metalloporphyrin protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in vivo.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070418
Title: Antiparkinsonian activity of L-propyl-L-leucyl-glycinamide or melanocyte-inhibiting factor in MPTP-treated common marmosets.
Journal: Movement disorders : official journal of the Movement Disorder Society 20070415
Title: Attenuation of 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine induced nigrostriatal toxicity in mice by N-acetyl cysteine.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20070415
Title: The COX-2 inhibitor parecoxib produces neuroprotective effects in MPTP-lesioned rats.
Journal: European journal of pharmacology 20070410
Title: Chronic ferritin expression within murine dopaminergic midbrain neurons results in a progressive age-related neurodegeneration.
Journal: Brain research 20070406
Title: Enhanced preproenkephalin-B-derived opioid transmission in striatum and subthalamic nucleus converges upon globus pallidus internalis in L-3,4-dihydroxyphenylalanine-induced dyskinesia.
Journal: Biological psychiatry 20070401
Title: TNF-alpha knockout and minocycline treatment attenuates blood-brain barrier leakage in MPTP-treated mice.
Journal: Neurobiology of disease 20070401
Title: Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism.
Journal: Neurobiology of disease 20070401
Title: Oxidative damage in nucleic acids and Parkinson's disease.
Journal: Journal of neuroscience research 20070401
Title: DJ-1 and Parkin modulate dopamine-dependent behavior and inhibit MPTP-induced nigral dopamine neuron loss in mice.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20070401
Title: Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERalpha in primary cultures of mouse mesencephalon.
Journal: Experimental neurology 20070401
Title: Motor cortex stimulation: mild transient benefit in a primate model of Parkinson disease.
Journal: Journal of neurosurgery 20070401
Title: Epidemiology of Parkinson's disease.
Journal: Disease-a-month : DM 20070401
Title: Long-lasting reactive changes observed in microglia in the striatal and substantia nigral of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Brain research 20070323
Title: Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070321
Title: Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson's disease.
Journal: Neuroscience 20070316
Title: Lipid-lowering drugs in the MPTP mouse model of Parkinson's disease: fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not.
Journal: Brain research 20070302
Title: Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070301
Title: Changes in the neuronal activity in the pedunculopontine nucleus in chronic MPTP-treated primates: an in situ hybridization study of cytochrome oxidase subunit I, choline acetyl transferase and substance P mRNA expression.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20070301
Title: Decreased expression of l-dopa-induced dyskinesia by switching to ropinirole in MPTP-treated common marmosets.
Journal: Experimental neurology 20070301
Title: Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo.
Journal: The Journal of pharmacology and experimental therapeutics 20070301
Title: The isolation of neural stem cells from the olfactory bulb of Parkinson's disease model.
Journal: Neuroscience research 20070301
Title: Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system.
Journal: PLoS biology 20070301
Title: Impact of chronic subthalamic high-frequency stimulation on metabolic basal ganglia activity: a 2-deoxyglucose uptake and cytochrome oxidase mRNA study in a macaque model of Parkinson's disease.
Journal: The European journal of neuroscience 20070301
Title: Manganese does not alter the severe neurotoxicity of MPTP.
Journal: Human & experimental toxicology 20070301
Title: Acupuncture inhibits microglial activation and inflammatory events in the MPTP-induced mouse model.
Journal: Brain research 20070202
Title: The novel squamosamide derivative (compound FLZ) attenuated 1-methyl, 4-phenyl-pyridinium ion (MPP+)-induced apoptosis and alternations of related signal transduction in SH-SY5Y cells.
Journal: Neuropharmacology 20070201
Title: Tamoxifen effect on L-DOPA induced response complications in parkinsonian rats and primates.
Journal: Neuropharmacology 20070201
Title: GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action.
Journal: Neurobiology of disease 20070201
Title: CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal: Journal of neuroimmunology 20070201
Title: Prodromal non-motor symptoms of Parkinson's disease.
Journal: Neuropsychiatric disease and treatment 20070201
Title: Chemokines in the MPTP model of Parkinson's disease: absence of CCL2 and its receptor CCR2 does not protect against striatal neurodegeneration.
Journal: Brain research 20070112
Title: Cytotoxicity of 17 tetrahydroisoquinoline derivatives in SH-SY5Y human neuroblastoma cells is related to mitochondrial NADH-ubiquinone oxidoreductase inhibition.
Journal: Neurotoxicology 20070101
Title: Evaluation of acute antiapoptotic effects of Li+ in neuronal cell cultures.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20070101
Title: Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant.
Journal: Neurochemistry international 20070101
Title: Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.
Journal: American journal of physiology. Cell physiology 20070101
Title: Divergent mechanisms of paraquat, MPP+, and rotenone toxicity: oxidation of thioredoxin and caspase-3 activation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070101
Title: Obligatory role for complex I inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070101
Title: Activation of tyrosine kinase receptor signaling pathway by rasagiline facilitates neurorescue and restoration of nigrostriatal dopamine neurons in post-MPTP-induced parkinsonism.
Journal: Neurobiology of disease 20070101
Title: Transglutaminase 2 ablation leads to defective function of mitochondrial respiratory complex I affecting neuronal vulnerability in experimental models of extrapyramidal disorders.
Journal: Journal of neurochemistry 20070101
Title: Striatal delta opioid receptor binding in experimental models of Parkinson's disease and dyskinesia.
Journal: Movement disorders : official journal of the Movement Disorder Society 20070101
Title: A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101
Title: Levodopa-induced hyperactivity in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Movement disorders : official journal of the Movement Disorder Society 20070101
Title: Metabolic activity of cerebellar and basal ganglia-thalamic neurons is reduced in parkinsonism.
Journal: Brain : a journal of neurology 20070101
Title: Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death.
Journal: The American journal of pathology 20070101
Title: Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alpha-synuclein.
Journal: Journal of neuroinflammation 20070101
Title: Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra.
Journal: Molecular neurodegeneration 20070101
Title: Neuroprotective effect of ketamine/xylazine on two rat models of Parkinson's disease.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070101
Title: Alloimmunisation to donor antigens and immune rejection following foetal neural grafts to the brain in patients with Huntington's disease.
Journal: PloS one 20070101
Title: Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain.
Journal: Genome biology 20070101
Title: Role of mitochondrial dysfunction in Parkinson's disease: Implications for treatment.
Journal: Drugs & aging 20070101
Title: Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice.
Journal: BMC neuroscience 20070101
Title: XIAP protection of photoreceptors in animal models of retinitis pigmentosa.
Journal: PloS one 20070101
Title: Protocol for the MPTP mouse model of Parkinson's disease.
Journal: Nature protocols 20070101
Title: Modulating effect of Hypericum perforatum extract on astrocytes in MPTP induced Parkinson's disease in mice.
Journal: European review for medical and pharmacological sciences 20070101
Title: The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention.
Journal: Molecular cancer 20070101
Title: The neuroprotective effect of Withania somnifera root extract in MPTP-intoxicated mice: an analysis of behavioral and biochemical variables.
Journal: Cellular & molecular biology letters 20070101
Title: Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice.
Journal: Molecular neurodegeneration 20070101
Title: The role of the substantia nigra pars compacta in regulating sleep patterns in rats.
Journal: PloS one 20070101
Title: Antioxidative and anti-inflammatory effects of four cysteine-containing agents in striatum of MPTP-treated mice.
Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20070101
Title: Inflammation in Parkinson's diseases and other neurodegenerative diseases: cause and therapeutic implications.
Journal: Current pharmaceutical design 20070101
Title: [Involvement of the brain dopaminergic systems in the development of the MPTP-induced depressive state in rats].
Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20070101
Title: Inflammation in Parkinson's disease: causative or epiphenomenal?
Journal: Sub-cellular biochemistry 20070101
Title: Minocycline delayed photoreceptor death in rds mice through iNOS-dependent mechanism.
Journal: Molecular vision 20070101
Title: Minocycline and sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation.
Journal: Molecular vision 20070101
Title: Identification of novel proteins affected by rotenone in mitochondria of dopaminergic cells.
Journal: BMC neuroscience 20070101
Title: Nonhuman primate models of Parkinson's disease.
Journal: ILAR journal 20070101
Title: Enhanced astrocytic nitric oxide production and neuronal modifications in the neocortex of a NOS2 mutant mouse.
Journal: PloS one 20070101
Title: A unified framework for finding differentially expressed genes from microarray experiments.
Journal: BMC bioinformatics 20070101
Title: Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase.
Journal: Journal of neuroinflammation 20070101
Title: Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line.
Journal: BMC neuroscience 20070101
Title: CYP 2E1 mutant mice are resistant to DDC-induced enhancement of MPTP toxicity.
Journal: Journal of neural transmission. Supplementum 20070101
Title: A model of MPTP-induced Parkinson's disease in the goldfish.
Journal: Nature protocols 20070101
Title: Multilineage potential of stable human mesenchymal stem cell line derived from fetal marrow.
Journal: PloS one 20070101
Title: [Daphnia magna (straus): a new test object for modeling of dopaminergic neurotransmission deficiency induced by the selective neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20070101
Title: PET 6-[F]fluoro-L-m-tyrosine Studies of Dopaminergic Function in Human and Nonhuman Primates.
Journal: Frontiers in human neuroscience 20070101
Title: Human bone marrow-derived mesenchymal stem cells.
Journal: The Libyan journal of medicine 20070101
Title: Identification of genes related to Parkinson's disease using expressed sequence tags.
Journal: DNA research : an international journal for rapid publication of reports on genes and genomes 20061231
Title: Intrastriatal infusion of the Parkinsonian neurotoxin, MPP(+), induces damage of striatal cell nuclei in Sprague-Dawley rats.
Journal: Journal of chemical neuroanatomy 20061201
Title: Neuroanatomical mapping of DNA repair and antioxidative responses in mouse brain: Effects of a single dose of MPTP.
Journal: Neurotoxicology 20061201
Title: The risk is in the air: Intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease.
Journal: Experimental neurology 20061201
Title: In vivo modulation of the Parkinsonian phenotype by Nrf2.
Journal: Neurotoxicology 20061201
Title: In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates, the selective 5-hydroxytryptamine 1a agonist (R)-(+)-8-OHDPAT inhibits levodopa-induced dyskinesia but only with\ increased motor disability.
Journal: The Journal of pharmacology and experimental therapeutics 20061201
Title: Subthalamic nucleus neurones in slices from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mice show irregular, dopamine-reversible firing pattern changes, but without synchronous activity.
Journal: Neuroscience 20061201
Title: Metabolic aromatization of N-alkyl-1,2,3,4-tetrahydroquinoline substructures to quinolinium by human liver microsomes and horseradish peroxidase.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20061201
Title: Antiparkinsonian effects of the novel D3/D2 dopamine receptor agonist, S32504, in MPTP-lesioned marmosets: Mediation by D2, not D3, dopamine receptors.
Journal: Movement disorders : official journal of the Movement Disorder Society 20061201
Title: Mitochondrial complex-1 in Parkinson's disease.
Journal: Neurology India 20061201
Title: Mass spectrometric studies on 4-aryl-1-cyclopropyl-1,2-dihydropyridinyl derivatives: an examination of a novel fragmentation pathway.
Journal: Journal of mass spectrometry : JMS 20061201
Title: 3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061201
Title: alpha-Synuclein, oxidative stress and apoptosis from the perspective of a yeast model of Parkinson's disease.
Journal: FEMS yeast research 20061201
Title: Neuroprotection in Parkinson models varies with toxin administration protocol.
Journal: The European journal of neuroscience 20061201
Title: Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys.
Journal: Annals of neurology 20061201
Title: Place learning strategy of substantia nigra pars compacta-lesioned rats.
Journal: Behavioral neuroscience 20061201
Title: 1alpha,25-Dihydroxyvitamin D(3) Protects Dopaminergic Neurons in Rodent Models of Parkinson's Disease through Inhibition of Microglial Activation.
Journal: Journal of clinical neurology (Seoul, Korea) 20061201
Title: Enhanced neuroprotective effect by combination of bromocriptine and Hypericum perforatum extract against MPTP-induced neurotoxicity in mice.
Journal: Journal of the neurological sciences 20061115
Title: Ebselen effects on MPTP-induced neurotoxicity.
Journal: Brain research 20061106
Title: DHEA improves symptomatic treatment of moderately and severely impaired MPTP monkeys.
Journal: Neurobiology of aging 20061101
Title: Wld(S) mice are protected against the Parkinsonian mimetic MPTP.
Journal: Experimental neurology 20061101
Title: Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6.
Journal: Toxicology and applied pharmacology 20061101
Title: HSV-mediated delivery of erythropoietin restores dopaminergic function in MPTP-treated mice.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20061101
Title: Pharmacological characterization of psychosis-like behavior in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20061101
Title: Tetrandrine selectively protects against amyloid-beta protein - but not against MPTP-induced cytotoxicity in SK-N-SH neuroblastoma cells.
Journal: Planta medica 20061101
Title: Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels.
Journal: Journal of neurochemistry 20061101
Title: Implications for estrogens in Parkinson's disease: an epidemiological approach.
Journal: Annals of the New York Academy of Sciences 20061101
Title: Activities of prolyl endopeptidase and dipeptidyl peptidase IV in brain structures of rats with dopamine deficiency-dependent MPTP-induced depressive syndrome.
Journal: Bulletin of experimental biology and medicine 20061101
Title: Dynamic modeling of alpha-synuclein aggregation for the sporadic and genetic forms of Parkinson's disease.
Journal: Neuroscience 20061027
Title: Distinct structure and activity of monoamine oxidase in the brain of zebrafish (Danio rerio).
Journal: The Journal of comparative neurology 20061010
Title: Dopamine turnover is upregulated in the caudate/putamen of asymptomatic MPTP-treated rhesus monkeys.
Journal: Neurochemistry international 20061001
Title: Does increased excitatory drive from the subthalamic nucleus contribute to dopaminergic neuronal death in Parkinson's disease?
Journal: Experimental neurology 20061001
Title: Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20061001
Title: Behavioral models of Parkinson's disease in rodents: a new look at an old problem.
Journal: Movement disorders : official journal of the Movement Disorder Society 20061001
Title: Partial recovery of striatal nicotinic receptors in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned monkeys with chronic oral nicotine.
Journal: The Journal of pharmacology and experimental therapeutics 20061001
Title: Translation of nondopaminergic treatments for levodopa-induced dyskinesia from MPTP-lesioned nonhuman primates to phase IIa clinical studies: keys to success and roads to failure.
Journal: Movement disorders : official journal of the Movement Disorder Society 20061001
Title: Persistent penetration of MPTP through the nasal route induces Parkinson's disease in mice.
Journal: The European journal of neuroscience 20061001
Title: Effects of nicotinic therapies on attention and executive functions in chronic low-dose MPTP-treated monkeys.
Journal: The European journal of neuroscience 20061001
Title: Further validation of LABORAS using various dopaminergic manipulations in mice including MPTP-induced nigro-striatal degeneration.
Journal: Journal of neuroscience methods 20060930
Title: The novel adenosine A2a receptor antagonist ST1535 potentiates the effects of a threshold dose of L-DOPA in MPTP treated common marmosets.
Journal: European journal of pharmacology 20060928
Title: Nitric oxide and MPP+-induced hydroxyl radical generation.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20060901
Title: Potentiating effect of the ATP-sensitive potassium channel blocker glibenclamide on complex I inhibitor neurotoxicity in vitro and in vivo.
Journal: Neurotoxicology 20060901
Title: Prevention of dyskinesia by an NMDA receptor antagonist in MPTP monkeys: effect on adenosine A2A receptors.
Journal: Synapse (New York, N.Y.) 20060901
Title: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced acute transient dystonia in monkeys associated with low striatal dopamine.
Journal: Neuroscience 20060901
Title: Genetic vitamin E deficiency does not affect MPTP susceptibility in the mouse brain.
Journal: Journal of neurochemistry 20060901
Title: Chronic oral nicotine treatment protects against striatal degeneration in MPTP-treated primates.
Journal: Journal of neurochemistry 20060901
Title: A call for clinically driven experimental design in assessing neuroprotection in experimental Parkinsonism.
Journal: Behavioural pharmacology 20060901
Title: Neuroprotective effects of modafinil in a marmoset Parkinson model: behavioral and neurochemical aspects.
Journal: Behavioural pharmacology 20060901
Title: Parkinson's disease-like syndrome in rats induced by 2,9-dimethyl-beta-carbolinium ion, a beta-carboline occurring in the human brain.
Journal: Behavioural pharmacology 20060901
Title: Evidence of apoptosis in the subventricular zone and rostral migratory stream in the MPTP mouse model of Parkinson disease.
Journal: Journal of neuropathology and experimental neurology 20060901
Title: Dopamine receptor agonists and levodopa and inducing psychosis-like behavior in the MPTP primate model of Parkinson disease.
Journal: Archives of neurology 20060901
Title: Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability.
Journal: PLoS computational biology 20060901
Title: Alterations of the expression and activity of midbrain nitric oxide synthase and soluble guanylyl cyclase in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.
Journal: Neuroscience 20060825
Title: Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/Bl mice.
Journal: The Journal of comparative neurology 20060820
Title: Dopamine replacement therapy does not restore the full spectrum of normal pallidal activity in the 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine primate model of Parkinsonism.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060802
Title: The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal.
Journal: Journal of molecular medicine (Berlin, Germany) 20060801
Title: Synthetic bovine proline-rich-polypeptides generate hydroxyl radicals and fail to protect dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity in mice.
Journal: Neuropeptides 20060801
Title: Basal ganglia lesions after MPTP administration in rhesus monkeys.
Journal: Neurobiology of disease 20060801
Title: Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801
Title: Convergent roles of alpha-synuclein, DA metabolism, and the ubiquitin-proteasome system in nigrostriatal toxicity.
Journal: Annals of the New York Academy of Sciences 20060801
Title: Inclusion dynamics in PC12 is comparable between amphetamines and MPTP.
Journal: Annals of the New York Academy of Sciences 20060801
Title: Calpain activation in apoptosis of motoneurons in cell culture models of experimental parkinsonism.
Journal: Annals of the New York Academy of Sciences 20060801
Title: gamma-Tocopherol attenuates MPTP-induced dopamine loss more efficiently than alpha-tocopherol in mouse brain.
Journal: Neuroscience letters 20060731
Title: Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060705
Title: Endogenously nitrated proteins in mouse brain: links to neurodegenerative disease.
Journal: Biochemistry 20060704
Title: 5-HT1A receptor agonist-mediated protection from MPTP toxicity in mouse and macaque models of Parkinson's disease.
Journal: Neurobiology of disease 20060701
Title: Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism.
Journal: Neuropharmacology 20060701
Title: Differential protection against MPTP or methamphetamine toxicity in dopamine neurons by deletion of ppN/OFQ expression.
Journal: Journal of neurochemistry 20060701
Title: Parkinsonism-preventing activity of 1-methyl-1,2,3,4-tetrahydroisoquinoline derivatives in C57BL mouse in vivo.
Journal: Biological & pharmaceutical bulletin 20060701
Title: Comparison of [18F]FDOPA, [18F]FMT and [18F]FECNT for imaging dopaminergic neurotransmission in mice.
Journal: Nuclear medicine and biology 20060701
Title: (-)-Epigallocatechin gallate regulates dopamine transporter internalization via protein kinase C-dependent pathway.
Journal: Brain research 20060630
Title: Early signs of neuronal apoptosis in the substantia nigra pars compacta of the progressive neurodegenerative mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model of Parkinson's disease.
Journal: Neuroscience 20060619
Title: Age-related severity of dopaminergic neurodegeneration to MPTP neurotoxicity causes motor dysfunction in C57BL/6 mice.
Journal: Neuroscience letters 20060619
Title: Doxycycline-regulated co-expression of GDNF and TH in PC12 cells.
Journal: Neuroscience letters 20060619
Title: Identification of far upstream element-binding protein-1 as an authentic Parkin substrate.
Journal: The Journal of biological chemistry 20060616
Title: Potential neuroprotective effect of low dose whole-body gamma-irradiation against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic toxicity in C57 mice.
Journal: Neuroscience letters 20060612
Title: Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.
Journal: Neurobiology of aging 20060601
Title: Discordant regulatory changes in monocrotaline-induced megalocytosis of lung arterial endothelial and alveolar epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060601
Title: Lesions in monkey globus pallidus externus exacerbate parkinsonian symptoms.
Journal: Experimental neurology 20060601
Title: Histamine H3 receptor agonists reduce L-dopa-induced chorea, but not dystonia, in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20060601
Title: Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A1 receptor.
Journal: British journal of pharmacology 20060601
Title: Histological effects of intraputaminal infusion of glial cell line-derived neurotrophic factor in Parkinson disease model macaque monkeys.
Journal: Neurologia medico-chirurgica 20060601
Title: Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.
Journal: The European journal of neuroscience 20060601
Title: In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease.
Journal: The Journal of biological chemistry 20060519
Title: Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke.
Journal: Bioorganic & medicinal chemistry 20060515
Title: Local shuffling of spike trains boosts the accuracy of spike train spectral analysis.
Journal: Journal of neurophysiology 20060501
Title: Clozapine modulates aromatic L-amino acid decarboxylase activity in mouse striatum.
Journal: The Journal of pharmacology and experimental therapeutics 20060501
Title: Enhanced de novo neurogenesis and dopaminergic neurogenesis in the substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease-like mice.
Journal: Stem cells (Dayton, Ohio) 20060501
Title: New striatal dopamine neurons in MPTP-treated macaques result from a phenotypic shift and not neurogenesis.
Journal: Brain : a journal of neurology 20060501
Title: Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease.
Journal: Journal of neurochemistry 20060501
Title: Attenuation of MPTP-induced neurotoxicity and locomotor dysfunction in Nucling-deficient mice via suppression of the apoptosome pathway.
Journal: Journal of neurochemistry 20060501
Title: [125I]Iodomethyllycaconitine binds to alpha7 nicotinic acetylcholine receptors in monkey brain.
Journal: The European journal of neuroscience 20060501
Title: Neuroprotection by transgenic expression of glucose-6-phosphate dehydrogenase in dopaminergic nigrostriatal neurons of mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060426
Title: Chronic oral nicotine normalizes dopaminergic function and synaptic plasticity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned primates.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060426
Title: Pedunculopontine nucleus electric stimulation alleviates akinesia independently of dopaminergic mechanisms.
Journal: Neuroreport 20060424
Title: Estrogen down-regulates glial activation in male mice following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication.
Journal: Brain research 20060421
Title: Proteomic analysis of microglial contribution to mouse strain-dependent dopaminergic neurotoxicity.
Journal: Glia 20060415
Title: Rifampicin attenuates the MPTP-induced neurotoxicity in mouse brain.
Journal: Brain research 20060412
Title: Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson's disease.
Journal: Brain research 20060412
Title: MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Cell death and differentiation 20060401
Title: Neuronal firing before and after burst discharges in the monkey basal ganglia is predictably patterned in the normal state and altered in parkinsonism.
Journal: Journal of neurophysiology 20060401
Title: Implication of the phosphatidylinositol-3 kinase/protein kinase B signaling pathway in the neuroprotective effect of estradiol in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.
Journal: Molecular pharmacology 20060401
Title: Synaptic microcircuitry of tyrosine hydroxylase-containing neurons and terminals in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys.
Journal: The Journal of comparative neurology 20060401
Title: Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060401
Title: MPTP treatment of common marmosets impairs proteasomal enzyme activity and decreases expression of structural and regulatory elements of the 26S proteasome.
Journal: The European journal of neuroscience 20060401
Title: Dopamine-dependent non-linear correlation between subthalamic rhythms in Parkinson's disease.
Journal: The Journal of physiology 20060315
Title: Norharman-induced motoric impairment in mice: neurodegeneration and glial activation in substantia nigra.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20060301
Title: Transforming growth factor beta2 haploinsufficient mice develop age-related nigrostriatal dopamine deficits.
Journal: Neurobiology of disease 20060301
Title: The neurotoxin 2'-NH2-MPTP degenerates serotonin axons and evokes increases in hippocampal BDNF.
Journal: Neuropharmacology 20060301
Title: Neuroprotective effect of arundic acid, an astrocyte-modulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity.
Journal: Neuropharmacology 20060301
Title: Tetrahydrobiopterin causes mitochondrial dysfunction in dopaminergic cells: implications for Parkinson's disease.
Journal: Neurochemistry international 20060301
Title: Effect of age on markers for monoaminergic neurons of normal and MPTP-lesioned rhesus monkeys: a multi-tracer PET study.
Journal: NeuroImage 20060301
Title: Role of extracellular-regulated kinase and c-Jun NH2-terminal kinase in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurofilament phosphorylation.
Journal: Journal of neuroscience research 20060301
Title: Pramipexole protects against MPTP toxicity in non-human primates.
Journal: Journal of neurochemistry 20060301
Title: Convection-enhanced delivery of adeno-associated virus type 2 (AAV2) into the striatum and transport of AAV2 within monkey brain.
Journal: Human gene therapy 20060301
Title: FGF-2 deficiency does not alter vulnerability of the dopaminergic nigrostriatal system towards MPTP intoxication in mice.
Journal: The European journal of neuroscience 20060301
Title: The potentiating effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on paraquat-induced neurochemical and behavioral changes in mice.
Journal: Pharmacology, biochemistry, and behavior 20060301
Title: Therapeutic effects of caloric stimulation and optokinetic stimulation on hemispatial neglect.
Journal: Journal of clinical neurology (Seoul, Korea) 20060301
Title: Cerebellar neurotransmission in attention-deficit/hyperactivity disorder: does dopamine neurotransmission occur in the cerebellar vermis?
Journal: Journal of neuroscience methods 20060215
Title: Divergent role of calcium on Abeta- and MPTP-induced cell death in SK-N-SH neuroblastoma.
Journal: Life sciences 20060209
Title: Adult and in utero exposure to cocaine alters sensitivity to the Parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Neuroscience 20060201
Title: Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys.
Journal: Experimental neurology 20060201
Title: Behavioral motor recovery in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned squirrel monkey (Saimiri sciureus): changes in striatal dopamine and expression of tyrosine hydroxylase and dopamine transporter proteins.
Journal: Journal of neuroscience research 20060201
Title: Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor-alpha.
Journal: Journal of neurochemistry 20060201
Title: Compensation in pre-synaptic dopaminergic function following nigrostriatal damage in primates.
Journal: Journal of neurochemistry 20060201
Title: Docosahexaenoic acid reduces levodopa-induced dyskinesias in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine monkeys.
Journal: Annals of neurology 20060201
Title: Pesticides and Parkinson's disease--is there a link?
Journal: Environmental health perspectives 20060201
Title: Decreased striatal levels of PEP-19 following MPTP lesion in the mouse.
Journal: Journal of proteome research 20060201
Title: H MRS identifies lactate rise in the striatum of MPTP-treated C57BL/6 mice.
Journal: The European journal of neuroscience 20060201
Title: Molecular biology, pharmacology and functional role of the plasma membrane dopamine transporter.
Journal: CNS & neurological disorders drug targets 20060201
Title: Ameliorating effect of dimethylsulfoniopropionate on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease of mice.
Journal: Journal of nutritional science and vitaminology 20060201
Title: Dopamine release in human neocortical slices: characterization of inhibitory autoreceptors and of nicotinic acetylcholine receptor-evoked release.
Journal: Brain research bulletin 20060130
Title: Estrogen prevents neuroprotection by caffeine in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111
Title: Prevention of levodopa-induced dyskinesias by a selective NR1A/2B N-methyl-D-aspartate receptor antagonist in parkinsonian monkeys: implication of preproenkephalin.
Journal: Movement disorders : official journal of the Movement Disorder Society 20060101
Title: Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: glia dictates resistance versus vulnerability to neurodegeneration.
Journal: Neuroscience 20060101
Title: cDNA array reveals increased expression of glucose-dependent insulinotropic polypeptide following chronic clozapine treatment: role in atypical antipsychotic drug-induced adverse metabolic effects.
Journal: The pharmacogenomics journal 20060101
Title: Mutagenic activity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Journal of applied genetics 20060101
Title: Serum antibodies from Parkinson's disease patients react with neuronal membrane proteins from a mouse dopaminergic cell line and affect its dopamine expression.
Journal: Journal of neuroinflammation 20060101
Title: Reduced 125I-meta-iodobenzylguanidine uptake and norepinephrine transporter density in the hearts of mice with MPTP-induced parkinsonism.
Journal: Nuclear medicine and biology 20060101
Title: Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease.
Journal: Journal of neuroinflammation 20060101
Title: N-acetyltransferase 2 (NAT2) gene polymorphisms in Parkinson's disease.
Journal: BMC medical genetics 20060101
Title: A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.
Journal: BMC neuroscience 20060101
Title: Melatonin in Alzheimer's disease and other neurodegenerative disorders.
Journal: Behavioral and brain functions : BBF 20060101
Title: Coenzyme Q(10) provides neuroprotection in iron-induced apoptosis in dopaminergic neurons.
Journal: Journal of molecular neuroscience : MN 20060101
Title: Can a single subunit yeast NADH dehydrogenase (Ndi1) remedy diseases caused by respiratory complex I defects?
Journal: Rejuvenation research 20060101
Title: Progressive dopamine neuron loss in Parkinson's disease: the multiple hit hypothesis.
Journal: Cell transplantation 20060101
Title: Neural repair strategies for Parkinson's disease: insights from primate models.
Journal: Cell transplantation 20060101
Title: Switching from levodopa to the long-acting dopamine D2/D3 agonist piribedil reduces the expression of dyskinesia while maintaining effective motor activity in MPTP-treated primates.
Journal: Clinical neuropharmacology 20060101
Title: Phosphatidylinositol transfer protein expression altered by aging and Parkinson disease.
Journal: Cellular and molecular neurobiology 20060101
Title: Curcumin protects mouse brain from oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: European review for medical and pharmacological sciences 20060101
Title: [Dependence of electromyographic reaction indices of the muscles-antagonists and stiffness of the elbow joint on its extension velocity before and after the injection of neurotoxin].
Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101
Title: Toxicity and metabolism of the chloral-derived mammalian alkaloid 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) in PC12 cells.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101
Title: A short overview on the role of alpha-synuclein and proteasome in experimental models of Parkinson's disease.
Journal: Journal of neural transmission. Supplementum 20060101
Title: Nongenetic causes of Parkinson's disease.
Journal: Journal of neural transmission. Supplementum 20060101
Title: Cytochrome P450 and Parkinson's disease: protective role of neuronal CYP 2E1 from MPTP toxicity.
Journal: Journal of neural transmission. Supplementum 20060101
Title: Controversies on new animal models of Parkinson's disease pro and con: the rotenone model of Parkinson's disease (PD).
Journal: Journal of neural transmission. Supplementum 20060101
Title: M30, a novel multifunctional neuroprotective drug with potent iron chelating and brain selective monoamine oxidase-ab inhibitory activity for Parkinson's disease.
Journal: Journal of neural transmission. Supplementum 20060101
Title: Anti-apoptotic gene therapy in Parkinson's disease.
Journal: Journal of neural transmission. Supplementum 20060101
Title: Complement activation in the Parkinson's disease substantia nigra: an immunocytochemical study.
Journal: Journal of neuroinflammation 20060101
Title: [Monoamine oxidase as a target for drug action].
Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20060101
Title: [Change of the nitric oxide synthase activity after administration of neurotoxic compounds in mice].
Journal: Acta pharmaceutica Hungarica 20060101
Title: Spirulina maxima pretreatment partially protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.
Journal: Nutritional neuroscience 20060101
Title: Oxidative stress and 17-alpha- and 17-beta-estradiol modulate neurofilaments differently.
Journal: Journal of molecular neuroscience : MN 20060101
Title: Molecular mechanism of the relation of monoamine oxidase B and its inhibitors to Parkinson's disease: possible implications of glial cells.
Journal: Journal of neural transmission. Supplementum 20060101
Title: Marmoset monkey models of Parkinson's disease: which model, when and why?
Journal: Brain research bulletin 20051230
Title: MPTP induces intranuclear rodlet formation in midbrain dopaminergic neurons.
Journal: Brain research 20051220
Title: Morphological impairments in retinal neurons of the scotopic visual pathway in a monkey model of Parkinson's disease.
Journal: The Journal of comparative neurology 20051212
Title: Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice.
Journal: The Journal of biological chemistry 20051202
Title: The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells.
Journal: Neurotoxicology 20051201
Title: Changes in cytoskeletal gene expression linked to MPTP-treatment in Mice.
Journal: Neurobiology of disease 20051201
Title: Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.
Journal: Neurobiology of disease 20051201
Title: Altered gene expression profiles reveal similarities and differences between Parkinson disease and model systems.
Journal: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 20051201
Title: K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons.
Journal: Nature neuroscience 20051201
Title: Down-regulation of metabotropic glutamate receptor 1alpha in globus pallidus and substantia nigra of parkinsonian monkeys.
Journal: The European journal of neuroscience 20051201
Title: Hormones are key actors in gene x environment interactions programming the vulnerability to Parkinson's disease: glia as a common final pathway.
Journal: Annals of the New York Academy of Sciences 20051201
Title: Neuroprotection of MPTP-induced toxicity in zebrafish dopaminergic neurons.
Journal: Brain research. Molecular brain research 20051130
Title: Heat shock proteins protect both MPP(+) and paraquat neurotoxicity.
Journal: Brain research bulletin 20051130
Title: Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction.
Journal: Gene 20051121
Title: Expression of GAD65 and GAD67 immunoreactivity in MPTP-treated monkeys with or without L-DOPA administration.
Journal: Neurobiology of disease 20051101
Title: Glia cell number modulates sensitivity to MPTP in mice.
Journal: Glia 20051101
Title: Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl.
Journal: Molecular pharmacology 20051101
Title: CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism.
Journal: Journal of neurochemistry 20051101
Title: Paraquat neurotoxicity is distinct from that of MPTP and rotenone.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051101
Title: Increased plasma levels of TNF-alpha but not of IL1-beta in MPTP-treated monkeys one year after the MPTP administration.
Journal: Parkinsonism & related disorders 20051101
Title: Cell survival patterns in the pedunculopontine tegmental nucleus of methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys and 6OHDA-lesioned rats: evidence for differences to idiopathic Parkinson disease patients?
Journal: Anatomy and embryology 20051101
Title: Dopamine D3 receptor-preferring agonists induce neurotrophic effects on mesencephalic dopamine neurons.
Journal: The European journal of neuroscience 20051101
Title: Effects of mitochondrial toxins on the brain amino acid concentrations.
Journal: Neurochemical research 20051101
Title: [Effects of yinxing pingchan recipe and its components on activity of mitochondrial enzyme complex in brain of mice with Parkinson's disease].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20051101
Title: Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051019
Title: Comparison of bilaterally 6-OHDA- and MPTP-lesioned rats as models of the early phase of Parkinson's disease: histological, neurochemical, motor and memory alterations.
Journal: Journal of neuroscience methods 20051015
Title: A novel and selective monoamine oxidase B substrate.
Journal: Bioorganic & medicinal chemistry 20051015
Title: Sepiapterin attenuates 1-methyl-4-phenylpyridinium-induced apoptosis in neuroblastoma cells transfected with neuronal NOS: role of tetrahydrobiopterin, nitric oxide, and proteasome activation.
Journal: Free radical biology & medicine 20051015
Title: Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051012
Title: Intra-nigral MPTP lesion in rats: behavioral and autoradiography studies.
Journal: Experimental neurology 20051001
Title: 4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20051001
Title: Subthalamic high frequency stimulation resets subthalamic firing and reduces abnormal oscillations.
Journal: Brain : a journal of neurology 20051001
Title: Unraveling substantia nigra sequential gene expression in a progressive MPTP-lesioned macaque model of Parkinson's disease.
Journal: Neurobiology of disease 20051001
Title: Formation of stacking complexes between caffeine (1,2,3-trimethylxanthine) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine may attenuate biological effects of this neurotoxin.
Journal: Bioorganic chemistry 20051001
Title: Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases. In vivo selective brain monoamine oxidase inhibition and prevention of MPTP-induced striatal dopamine depletion.
Journal: Journal of neurochemistry 20051001
Title: [Animal models of parkinsonism].
Journal: Revue neurologique 20051001
Title: Neuroprotective therapy in Parkinson's disease: current status and new directions from experimental and genetic clues.
Journal: Journal of clinical neurology (Seoul, Korea) 20051001
Title: Swim-test as a function of motor impairment in MPTP model of Parkinson's disease: a comparative study in two mouse strains.
Journal: Behavioural brain research 20050908
Title: Decrease in alpha3*/alpha6* nicotinic receptors but not nicotine-evoked dopamine release in monkey brain after nigrostriatal damage.
Journal: Molecular pharmacology 20050901
Title: The effects of a selective dopamine D2 receptor agonist on behavioral and pathological outcome in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated squirrel monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20050901
Title: Early environmental origins of neurodegenerative disease in later life.
Journal: Environmental health perspectives 20050901
Title: The role of early life environmental risk factors in Parkinson disease: what is the evidence?
Journal: Environmental health perspectives 20050901
Title: Developmental pesticide models of the Parkinson disease phenotype.
Journal: Environmental health perspectives 20050901
Title: Differential survival patterns among midbrain dopaminergic cells of MPTP-treated monkeys and 6OHDA-lesioned rats.
Journal: Anatomy and embryology 20050901
Title: Apoptosis inducing factor mediates caspase-independent 1-methyl-4-phenylpyridinium toxicity in dopaminergic cells.
Journal: Journal of neurochemistry 20050901
Title: Unilateral pallidotomy in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets exhibiting levodopa-induced dyskinesia.
Journal: The European journal of neuroscience 20050901
Title: Cellular distribution of interleukin-1alpha-immunoreactivity after MPTP intoxication in mice.
Journal: Brain research. Molecular brain research 20050818
Title: Role of mitochondrial re-energization and Ca2+ influx in reperfusion injury of metabolically inhibited cardiac myocytes.
Journal: Cardiovascular research 20050801
Title: Dietary restriction affects striatal glutamate in the MPTP-induced mouse model of nigrostriatal degeneration.
Journal: Synapse (New York, N.Y.) 20050801
Title: MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contact.
Journal: Neuroscience research 20050801
Title: Melatonin protects against MPTP/MPP+ -induced mitochondrial DNA oxidative damage in vivo and in vitro.
Journal: Journal of pineal research 20050801
Title: Naltrexone in the short-term decreases antiparkinsonian response to l-Dopa and in the long-term increases dyskinesias in drug-naïve parkinsonian monkeys.
Journal: Neuropharmacology 20050801
Title: Oestrogens prevent loss of dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) in substantia nigra of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice.
Journal: Journal of neuroendocrinology 20050801
Title: Synthesis and neurotoxicity of tetrahydroisoquinoline derivatives for studying Parkinson's disease.
Journal: Biological & pharmaceutical bulletin 20050801
Title: In vivo models of multiple system atrophy.
Journal: Movement disorders : official journal of the Movement Disorder Society 20050801
Title: Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.
Journal: Journal of neurochemistry 20050801
Title: Effects of metabolic modifiers such as carnitines, coenzyme Q10, and PUFAs against different forms of neurotoxic insults: metabolic inhibitors, MPTP, and methamphetamine.
Journal: Annals of the New York Academy of Sciences 20050801
Title: Pinhole SPECT imaging of dopamine transporters correlates with dopamine transporter immunohistochemical analysis in the MPTP mouse model of Parkinson's disease.
Journal: NeuroImage 20050715
Title: Pig brain stereotaxic standard space: mapping of cerebral blood flow normative values and effect of MPTP-lesioning.
Journal: Brain research bulletin 20050715
Title: Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713
Title: MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701
Title: Acute repetitive transcranial magnetic stimulation reactivates dopaminergic system in lesion rats.
Journal: Neuroscience letters 20050701
Title: A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701
Title: Possibility for neurogenesis in substantia nigra of parkinsonian brain.
Journal: Annals of neurology 20050701
Title: Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys.
Journal: Movement disorders : official journal of the Movement Disorder Society 20050701
Title: Levodopa-induced dyskinesia in MPTP-treated macaques is not dependent on the extent and pattern of nigrostrial lesioning.
Journal: The European journal of neuroscience 20050701
Title: The acute and the long-term effects of nigral lipopolysaccharide administration on dopaminergic dysfunction and glial cell activation.
Journal: The European journal of neuroscience 20050701
Title: Study of antiparkinsonic activity of panavir on a model of Parkinson syndrome induced by systemic administration of MPTP to outbred rats and C57Bl/6 mice.
Journal: Bulletin of experimental biology and medicine 20050701
Title: Toxin-induced models of Parkinson's disease.
Journal: NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 20050701
Title: MPTP-induced models of Parkinson's disease in mice and non-human primates.
Journal: Current protocols in pharmacology 20050701
Title: The Webcam system: a simple, automated, computer-based video system for quantitative measurement of movement in nonhuman primates.
Journal: Journal of neuroscience methods 20050630
Title: Written in our genes?
Journal: Science (New York, N.Y.) 20050617
Title: Possible mechanisms of the protection of ginsenoside Re against MPTP-induced apoptosis in substantia nigra neurons of Parkinson's disease mouse model.
Journal: Journal of Asian natural products research 20050601
Title: Oxidative stress and inflammation in Parkinson's disease: is there a causal link?
Journal: Experimental neurology 20050601
Title: Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors.
Journal: Parkinsonism & related disorders 20050601
Title: Neuroinflammatory processes in Parkinson's disease.
Journal: Parkinsonism & related disorders 20050601
Title: [Effect of the oil from ganoderma lucidum spores on pathological changes in the substantia nigra and behaviors of MPTP-treated mice].
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050601
Title: Immunoautoradiographic analysis of NMDA receptor subunits and associated postsynaptic density proteins in the brain of dyskinetic MPTP-treated common marmosets.
Journal: The European journal of neuroscience 20050601
Title: Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade.
Journal: Purinergic signalling 20050601
Title: In mice, production of plasma IL-1 and IL-6 in response to MPTP is related to behavioral lateralization.
Journal: Brain research 20050531
Title: Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines.
Journal: Bioorganic & medicinal chemistry 20050516
Title: Temporal evolution of mouse striatal gene expression following MPTP injury.
Journal: Neurobiology of aging 20050501
Title: [Kinetic changes of plasma IL-1 and IL-6 levels in MPTP-induced Parkinson's disease model mice and their relationship with brain asymmetry].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20050501
Title: Induction of thioredoxin and mitochondrial survival proteins mediates preconditioning-induced cardioprotection and neuroprotection.
Journal: Annals of the New York Academy of Sciences 20050501
Title: LC-MS determination of MPTP at sub-ppm level in pethidine hydrochloride.
Journal: Journal of pharmaceutical and biomedical analysis 20050429
Title: Differential inflammatory activation of IL-6 (-/-) astrocytes.
Journal: Cytokine 20050421
Title: Selective glial cell line-derived neurotrophic factor production in adult dopaminergic carotid body cells in situ and after intrastriatal transplantation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420
Title: Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20050405
Title: Regulation of striatal preproenkephalin mRNA levels in MPTP-lesioned mice treated with estradiol.
Journal: Journal of neuroscience research 20050401
Title: Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity.
Journal: Journal of neurochemistry 20050401
Title: Glucocorticoid receptor-nitric oxide crosstalk and vulnerability to experimental parkinsonism: pivotal role for glia-neuron interactions.
Journal: Brain research. Brain research reviews 20050401
Title: Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease.
Journal: Journal of clinical neurology (Seoul, Korea) 20050401
Title: The MPTP model of Parkinson's disease.
Journal: Brain research. Molecular brain research 20050324
Title: Absence of inclusion body formation in the MPTP mouse model of Parkinson's disease.
Journal: Brain research. Molecular brain research 20050324
Title: Quantitative proteomic analysis of mitochondrial proteins: relevance to Lewy body formation and Parkinson's disease.
Journal: Brain research. Molecular brain research 20050324
Title: Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism.
Journal: Brain research. Molecular brain research 20050324
Title: Regulation of mitochondrial NADP+-dependent isocitrate dehydrogenase activity by glutathionylation.
Journal: The Journal of biological chemistry 20050318
Title: Chronic implantation of deep brain stimulation leads in animal models of neurological disorders.
Journal: Journal of neuroscience methods 20050315
Title: Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity.
Journal: Free radical biology & medicine 20050315
Title: Simvastatin prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion and protein tyrosine nitration in mice.
Journal: Brain research 20050310
Title: A synthetic human proline-rich-polypeptide enhances hydroxyl radical generation and fails to protect dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced toxicity in mice.
Journal: Neuroscience letters 20050303
Title: Multiple small doses of levodopa plus entacapone produce continuous dopaminergic stimulation and reduce dyskinesia induction in MPTP-treated drug-naive primates.
Journal: Movement disorders : official journal of the Movement Disorder Society 20050301
Title: Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates.
Journal: Experimental neurology 20050301
Title: Lesion of the substantia nigra, pars compacta impairs delayed alternation in a Y-maze in rats.
Journal: Experimental neurology 20050301
Title: Neural mechanisms underlying motor dysfunction as detected by the tail suspension test in MPTP-treated C57BL/6 mice.
Journal: Neuroscience research 20050301
Title: Disruption of lateral olivocochlear neurons via a dopaminergic neurotoxin depresses sound-evoked auditory nerve activity.
Journal: Journal of the Association for Research in Otolaryngology : JARO 20050301
Title: Viral vector mediated overexpression of human alpha-synuclein in the nigrostriatal dopaminergic neurons: a new model for Parkinson's disease.
Journal: CNS spectrums 20050301
Title: KW-6002 protects from MPTP induced dopaminergic toxicity in the mouse.
Journal: Neuropharmacology 20050301
Title: Zebrafish embryos are susceptible to the dopaminergic neurotoxin MPTP.
Journal: The European journal of neuroscience 20050301
Title: Tumor necrosis factor-alpha receptor ablation in a chronic MPTP mouse model of Parkinson's disease.
Journal: Neuroscience letters 20050227
Title: Acanthopanax senticosus Harms as a prophylactic for MPTP-induced Parkinson's disease in rats.
Journal: Journal of ethnopharmacology 20050227
Title: Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050216
Title: Thalamic neuronal activity in dopamine-depleted primates: evidence for a loss of functional segregation within basal ganglia circuits.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050209
Title: Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism.
Journal: Experimental neurology 20050201
Title: A novel thiol antioxidant that crosses the blood brain barrier protects dopaminergic neurons in experimental models of Parkinson's disease.
Journal: The European journal of neuroscience 20050201
Title: A modified MPTP treatment regime produces reproducible partial nigrostriatal lesions in common marmosets.
Journal: The European journal of neuroscience 20050201
Title: Measurement of mitochondrial respiration in permeabilized murine neuroblastoma (N-2alpha) cells, a simple and rapid in situ assay to investigate mitochondrial toxins.
Journal: Journal of biochemical and biophysical methods 20050131
Title: Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures.
Journal: Biochemical pharmacology 20050115
Title: Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050105
Title: Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model.
Journal: The Journal of clinical investigation 20050103
Title: Subunit composition of nicotinic receptors in monkey striatum: effect of treatments with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine or L-DOPA.
Journal: Molecular pharmacology 20050101
Title: Selective alterations of gene expression in mice induced by MPTP.
Journal: Synapse (New York, N.Y.) 20050101
Title: Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia.
Journal: Annals of neurology 20050101
Title: Effect of angiotensin-converting enzyme inhibitor perindopril on interneurons in MPTP-treated mice.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050101
Title: Physiological studies of information processing in the normal and Parkinsonian basal ganglia: pallidal activity in Go/No-Go task and following MPTP treatment.
Journal: Progress in brain research 20050101
Title: Hsp70 gene transfer by adeno-associated virus inhibits MPTP-induced nigrostriatal degeneration in the mouse model of Parkinson disease.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20050101
Title: Interleukine-1beta and interleukine-6 levels in striatum and other brain structures after MPTP treatment: influence of behavioral lateralization.
Journal: Journal of neuroimmunology 20050101
Title: A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities.
Journal: Experimental neurology 20050101
Title: Differential effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the olfactory bulb and the striatum in mice.
Journal: Neuroscience research 20050101
Title: Beta-carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway.
Journal: Neuropharmacology 20050101
Title: Autotoxicity, methylation and a road to the prevention of Parkinson's disease.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20050101
Title: Recovery from experimental Parkinson's disease in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride treated marmoset with the melatonin analogue ML-23.
Journal: Pharmacology, biochemistry, and behavior 20050101
Title: Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress.
Journal: Acta pharmacologica Sinica 20050101
Title: Immunization with myelin oligodendrocyte glycoprotein and complete Freund adjuvant partially protects dopaminergic neurons from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced damage in mouse model of Parkinson's disease.
Journal: Neuroscience 20050101
Title: Pharmacological manipulation of ataxia-telangiectasia kinase activity as a treatment for Parkinson's disease.
Journal: Medical hypotheses 20050101
Title: Potential neuroprotective effect of t-butylhydroquinone against neurotoxicity-induced by 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) in mice.
Journal: Journal of biochemical and molecular toxicology 20050101
Title: The chemistry and pharmacology of tetrahydropyridines.
Journal: Current medicinal chemistry 20050101
Title: Inflammatory process in Parkinson's disease: role for cytokines.
Journal: Current pharmaceutical design 20050101
Title: Enhanced striatal opioid receptor-mediated G-protein activation in L-DOPA-treated dyskinetic monkeys.
Journal: Neuroscience 20050101
Title: Dyskinesias occur in response to saline and naltrexone alone after priming with combination of dopaminergic agents and naltrexone in the MPTP parkinsonian monkeys.
Journal: Neurobiology of disease 20050101
Title: LY503430: pharmacology, pharmacokinetics, and effects in rodent models of Parkinson's disease.
Journal: CNS drug reviews 20050101
Title: Reactive oxygen and nitrogen species: weapons of neuronal destruction in models of Parkinson's disease.
Journal: Antioxidants & redox signaling 20050101
Title: MPTP and SNpc DA neuronal vulnerability: role of dopamine, superoxide and nitric oxide in neurotoxicity. Minireview.
Journal: Neurotoxicity research 20050101
Title: [Neurodegenerative alterations induced by MPTP neurotoxin in senescence accelerated mice essay].
Journal: Uspekhi fiziologicheskikh nauk 20050101
Title: Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures.
Journal: Cell transplantation 20050101
Title: Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition.
Journal: Journal of neuroinflammation 20050101
Title: Influence of paraquat on dopaminergic transporter in the rat brain.
Journal: Pharmacological reports : PR 20050101
Title: Adenosine-dopamine interactions revealed in knockout mice.
Journal: Journal of molecular neuroscience : MN 20050101
Title: A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools.
Journal: BMC bioinformatics 20050101
Title: Gait dynamics in mouse models of Parkinson's disease and Huntington's disease.
Journal: Journal of neuroengineering and rehabilitation 20050101
Title: MAOA haplotypes associated with thrombocyte-MAO activity.
Journal: BMC genetics 20050101
Title: Neurochemical evidence for agmatine modulation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity.
Journal: Neurochemical research 20050101
Title: l-dopa-induced reversal in striatal glutamate following partial depletion of nigrostriatal dopamine with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Neuroscience 20050101
Title: [Evoked potentials of the somatic cortex, thalamus, and electromyographic reactions of the cat shoulder muscles elicited by elbow joint straightening in norm and after injection of neurotoxin].
Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101
Title: MPTP treatment impairs tyrosine hydroxylase immunopositive fibers not only in the striatum, but also in the amygdala.
Journal: Neuro-degenerative diseases 20050101
Title: Modeling neurodegenerative diseases in vivo review.
Journal: Neuro-degenerative diseases 20050101
Title: Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in mice.
Journal: Brain research 20041224
Title: Effect of estrogen receptor agonists treatment in MPTP mice: evidence of neuroprotection by an ER alpha agonist.
Journal: Neuropharmacology 20041201
Title: Lack of evidence of direct mitochondrial involvement in the neuroprotective effect of minocycline.
Journal: European journal of pharmacology 20041128
Title: Striatal preprotachykinin gene expression reflects parkinsonian signs.
Journal: Neuroreport 20041115
Title: Upregulation of guanylyl cyclase expression and activity in striatum of MPTP-induced parkinsonism in mice.
Journal: Biochemical and biophysical research communications 20041105
Title: Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20041101
Title: Prolongation of levodopa responses by glycineB antagonists in parkinsonian primates.
Journal: Annals of neurology 20041101
Title: Astroglial plasticity and glutamate function in a chronic mouse model of Parkinson's disease.
Journal: Experimental neurology 20041101
Title: A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo.
Journal: Neurobiology of disease 20041101
Title: Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism.
Journal: PLoS biology 20041101
Title: Detection and semi-quantitative determination of low abundance GFAP mRNA in mouse brain by capillary electrophoresis coupled with laser-induced fluorescence.
Journal: Brain research. Brain research protocols 20041101
Title: Vigilance states in a parkinsonian model, the MPTP mouse.
Journal: The European journal of neuroscience 20041101
Title: Effect of 5-HT1B/D receptor agonist and antagonist administration on motor function in haloperidol and MPTP-treated common marmosets.
Journal: Pharmacology, biochemistry, and behavior 20041101
Title: Mapping dopamine function in primates using pharmacologic magnetic resonance imaging.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041027
Title: Effects of blocking the dopamine biosynthesis and of neurotoxic dopamine depletion with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on voluntary wheel running in mice.
Journal: Behavioural brain research 20041005
Title: Acoustic startle response, prepulse inhibition, and spontaneous locomotor activity in MPTP-treated mice.
Journal: Behavioural brain research 20041005
Title: Discharge rate of substantia nigra pars reticulata neurons is reduced in non-parkinsonian monkeys with apomorphine-induced orofacial dyskinesia.
Journal: Journal of neurophysiology 20041001
Title: Dexamethasone protects against dopaminergic neurons damage in a mouse model of Parkinson's disease.
Journal: International immunopharmacology 20041001
Title: Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology.
Journal: Brain research 20041001
Title: PET imaging of implanted human retinal pigment epithelial cells in the MPTP-induced primate model of Parkinson's disease.
Journal: Experimental neurology 20041001
Title: Regulation of dopamine receptor and neuropeptide expression in the basal ganglia of monkeys treated with MPTP.
Journal: Experimental neurology 20041001
Title: 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH.
Journal: Journal of neurochemistry 20041001
Title: Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.
Journal: Journal of neurochemistry 20041001
Title: Dopamine transporter: involvement in selective dopaminergic neurotoxicity and degeneration.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20041001
Title: Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP.
Journal: Cell and tissue research 20041001
Title: Role of mitochondrial dysfunction in neurotoxicity of MPP+: partial protection of PC12 cells by acetyl-L-carnitine.
Journal: Annals of the New York Academy of Sciences 20041001
Title: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned model of parkinson's disease, with emphasis on mice and nonhuman primates.
Journal: Comparative medicine 20041001
Title: Increased GAD67 mRNA levels are correlated with in vivo GABA synthesis in the MPTP-treated catecholamine-depleted goldfish brain.
Journal: Brain research. Molecular brain research 20040928
Title: The cytotoxic activity of lactoperoxidase: enhancement and inhibition by neuroactive compounds.
Journal: Free radical biology & medicine 20040915
Title: Proteasome-dependent degradation of cyclin D1 in 1-methyl-4-phenylpyridinium ion (MPP+)-induced cell cycle arrest.
Journal: The Journal of biological chemistry 20040910
Title: Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse.
Journal: Brain research 20040903
Title: Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration.
Journal: Neurotoxicology 20040901
Title: Iron-sulfur enzyme mediated mitochondrial superoxide toxicity in experimental Parkinson's disease.
Journal: Journal of neurochemistry 20040901
Title: Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901
Title: The role of membrane and vesicular monoamine transporters in the neurotoxic and hypothermic effects of 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH(2)-MPTP).
Journal: Molecular pharmacology 20040901
Title: Comparison of two methods for the analysis of [18F]6-fluoro-L-m-tyrosine PET data.
Journal: NeuroImage 20040901
Title: Neuroprotective effect of the angiotensin-converting enzyme inhibitor perindopril in MPTP-treated mice.
Journal: Neurological research 20040901
Title: Attention and executive function deficits in chronic low-dose MPTP-treated non-human primates.
Journal: The European journal of neuroscience 20040901
Title: Is the unilateral lesion of the left substantia nigra pars compacta sufficient to induce working memory impairment in rats?
Journal: Neurobiology of learning and memory 20040901
Title: Coordinated behavior of mitochondria in both space and time: a reactive oxygen species-activated wave of mitochondrial depolarization.
Journal: Biophysical journal 20040901
Title: Postmortem studies in Parkinson's disease.
Journal: Dialogues in clinical neuroscience 20040901
Title: Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder.
Journal: Dialogues in clinical neuroscience 20040901
Title: High-performance liquid chromatography/tandem mass spectrometry assay for the determination of 1-methyl-4-phenyl pyridinium (MPP+) in brain tissue homogenates.
Journal: Journal of neuroscience methods 20040830
Title: Dysregulation of gene expression in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse substantia nigra.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040825
Title: Folate intake and risk of Parkinson's disease.
Journal: American journal of epidemiology 20040815
Title: The NR2B-selective NMDA receptor antagonist CP-101,606 exacerbates L-DOPA-induced dyskinesia and provides mild potentiation of anti-parkinsonian effects of L-DOPA in the MPTP-lesioned marmoset model of Parkinson's disease.
Journal: Experimental neurology 20040801
Title: Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia.
Journal: Journal of neuroscience research 20040801
Title: Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.
Journal: Neurobiology of disease 20040801
Title: Olfactory impairment and Parkinson's disease-like symptoms observed in the common marmoset following administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Acta oto-laryngologica. Supplementum 20040801
Title: Neuroprotective effects of Bak Foong Pill in 1-methyl-4-phenyl-1,2,3,6-tetrahyrdropyridine (MPTP)-induced Parkinson's disease model mice.
Journal: Biological & pharmaceutical bulletin 20040801
Title: MPTP as a mitochondrial neurotoxic model of Parkinson's disease.
Journal: Journal of bioenergetics and biomembranes 20040801
Title: Acetyl-L-carnitine prevents total body hydroxyl free radical and uric acid production induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the rat.
Journal: Life sciences 20040723
Title: Role of external pallidal segment in primate parkinsonism: comparison of the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism and lesions of the external pallidal segment.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040721
Title: Attentional cueing reverses deficits in spatial working memory task performance in chronic low dose MPTP-treated monkeys.
Journal: Behavioural brain research 20040709
Title: Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 20040701
Title: The role of Ca2+ channel modulation in the neuroprotective actions of estrogen in beta-amyloid protein and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) cytotoxic models.
Journal: Neurochemistry international 20040701
Title: Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701
Title: Selective blockade of D(3) dopamine receptors enhances the anti-parkinsonian properties of ropinirole and levodopa in the MPTP-lesioned primate.
Journal: Experimental neurology 20040701
Title: Relevance of the MPTP primate model in the study of dyskinesia priming mechanisms.
Journal: Parkinsonism & related disorders 20040701
Title: Prolonged biologically active transgene expression driven by HSV LAP2 in brain in vivo.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20040701
Title: L-3-hydroxyacyl-CoA dehydrogenase II protects in a model of Parkinson's disease.
Journal: Annals of neurology 20040701
Title: Recent failures of new potential symptomatic treatments for Parkinson's disease: causes and solutions.
Journal: Movement disorders : official journal of the Movement Disorder Society 20040701
Title: An application of a new planar positron imaging system (PPIS) in a small animal: MPTP-induced parkinsonism in mouse.
Journal: Annals of nuclear medicine 20040701
Title: Chemoarchitectonic heterogeneities in the primate zona incerta: clinical and functional implications.
Journal: Journal of neurocytology 20040701
Title: Spike synchronization in the cortex/basal-ganglia networks of Parkinsonian primates reflects global dynamics of the local field potentials.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040630
Title: The biogenic trace amine tyramine induces a pronounced hydroxyl radical production via a monoamine oxidase dependent mechanism: an in vivo microdialysis study in mouse striatum.
Journal: Brain research 20040625
Title: S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: II. Actions in rodent, primate, and cellular models of antiparkinsonian activity in comparison to ropinirole.
Journal: The Journal of pharmacology and experimental therapeutics 20040601
Title: Neuroprotective effects of a novel poly(ADP-ribose) polymerase-1 inhibitor, 2-[3-[4-(4-chlorophenyl)-1-piperazinyl] propyl]-4(3H)-quinazolinone (FR255595), in an in vitro model of cell death and in mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 20040601
Title: Altered nitric oxide production in mouse brain after administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridin or methamphetamine.
Journal: Neurochemistry international 20040601
Title: Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and Bax.
Journal: Neuropharmacology 20040601
Title: The role of NF-kappaB in 6-hydroxydopamine- and TNFalpha-induced apoptosis of PC12 cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040601
Title: Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice.
Journal: Journal of neurochemistry 20040601
Title: Neuroprotective effects of phenylethanoid glycosides from Cistanches salsa against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic toxicity in C57 mice.
Journal: Biological & pharmaceutical bulletin 20040601
Title: The opioid agonist morphine decreases the dyskinetic response to dopaminergic agents in parkinsonian monkeys.
Journal: Neurobiology of disease 20040601
Title: Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease.
Journal: The European journal of neuroscience 20040601
Title: Development of calorie restriction mimetics as a prolongevity strategy.
Journal: Annals of the New York Academy of Sciences 20040601
Title: The levels of plasma IL-1beta, IL-6 of C57BL/6J mice treated with MPTP and brain lateralization.
Journal: Cellular & molecular immunology 20040601
Title: Striatal tyrosine hydroxylase immunoreactive neurons are induced by L-dihydroxyphenylalanine and nerve growth factor treatment in 6-hydroxydopamine lesioned rats.
Journal: Neuroscience letters 20040520
Title: Tyrosine hydroxylase and dopamine transporter expression following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration of the mouse nigrostriatal pathway.
Journal: Journal of neuroscience research 20040515
Title: Induction of gp130-related cytokines and activation of JAK2/STAT3 pathway in astrocytes precedes up-regulation of glial fibrillary acidic protein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of neurodegeneration: key signaling pathway for astrogliosis in vivo?
Journal: The Journal of biological chemistry 20040507
Title: The neuroprotective effects of estrogen in SK-N-SH neuroblastoma cell cultures.
Journal: Neurochemistry international 20040501
Title: Immunofluorescent labeling of increased calpain expression and neuronal death in the spinal cord of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.
Journal: Brain research 20040501
Title: Differential expression and ser897 phosphorylation of striatal N-methyl-d-aspartate receptor subunit NR1 in animal models of Parkinson's disease.
Journal: Experimental neurology 20040501
Title: Antiparkinsonian activity of Ro 25-6981, a NR2B subunit specific NMDA receptor antagonist, in animal models of Parkinson's disease.
Journal: Experimental neurology 20040501
Title: Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake.
Journal: Journal of neurochemistry 20040501
Title: Brain inflammation enhances 1-methyl-4-phenylpyridinium-evoked neurotoxicity in rats.
Journal: Toxicology and applied pharmacology 20040501
Title: Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure.
Journal: Glia 20040501
Title: Early administration of nicotinamide prevents learning and memory impairment in mice induced by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine.
Journal: Pharmacology, biochemistry, and behavior 20040501
Title: The neuroprotective effects of Semax in conditions of MPTP-induced lesions of the brain dopaminergic system.
Journal: Neuroscience and behavioral physiology 20040501
Title: 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide.
Journal: The Journal of biological chemistry 20040430
Title: Aging of the nigrostriatal system in the squirrel monkey.
Journal: The Journal of comparative neurology 20040412
Title: Acetaminophen and aspirin inhibit superoxide anion generation and lipid peroxidation, and protect against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats.
Journal: Neurochemistry international 20040401
Title: Commentary on 'Alpha-synuclein and mitochondria: a tangled skein'.
Journal: Experimental neurology 20040401
Title: Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.
Journal: Experimental neurology 20040401
Title: Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice.
Journal: Journal of neuropathology and experimental neurology 20040401
Title: Measurement of motor disability in MPTP-treated macaques using a telemetry system for estimating circadian motor activity.
Journal: Journal of neuroscience methods 20040315
Title: Differences in alpha7 nicotinic acetylcholine receptor binding in motor symptomatic and asymptomatic MPTP-treated monkeys.
Journal: Brain research 20040305
Title: Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040301
Title: Effect of melatonin on temporal changes of reactive oxygen species and glutathione after MPP(+) treatment in human astrocytoma U373MG cells.
Journal: Journal of pineal research 20040301
Title: Deep brain stimulation for Parkinson's disease: potential risk of tissue damage associated with external stimulation.
Journal: Annals of neurology 20040301
Title: Neuroprotective mechanism of modafinil on Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Acta pharmacologica Sinica 20040301
Title: Effect of a selective glutamate antagonist on L-dopa-induced dyskinesias in drug-naive parkinsonian monkeys.
Journal: Neurobiology of disease 20040301
Title: Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity.
Journal: Journal of neurochemistry 20040301
Title: Protective effects of neuronal nitric oxide synthase inhibitor in mouse brain against MPTP neurotoxicity: an immunohistological study.
Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20040301
Title: [Inflammation and Parkinson's disease].
Journal: Revista de neurologia 20040301
Title: Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.
Journal: Annals of the New York Academy of Sciences 20040301
Title: The role of the substantia nigra in cognitive activity in cats.
Journal: Neuroscience and behavioral physiology 20040301
Title: Differing response to antipsychotic therapy in schizophrenia: pharmacogenomic aspects.
Journal: Dialogues in clinical neuroscience 20040301
Title: Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040225
Title: Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040225
Title: Neurotrophic actions of the novel AMPA receptor potentiator, LY404187, in rodent models of Parkinson's disease.
Journal: European journal of pharmacology 20040220
Title: Levetiracetam improves choreic levodopa-induced dyskinesia in the MPTP-treated macaque.
Journal: European journal of pharmacology 20040206
Title: SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease.
Journal: Neuroscience research 20040201
Title: Long-term retention of neurotoxic beta-carbolines in brain neuromelanin.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20040201
Title: Dopamine agonist 3-PPP fails to protect against MPTP-induced toxicity.
Journal: Neurochemical research 20040201
Title: Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease.
Journal: Current drug targets 20040201
Title: Immunization of rats with conjugates of dopamine and serotonin with bovine serum albumin prevents the development of experimental MPTP-induced depressive syndrome (electrophysiological parameters).
Journal: Neuroscience and behavioral physiology 20040201
Title: Preclinical models of Parkinson's disease.
Journal: Current protocols in toxicology 20040201
Title: Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040128
Title: Behavioural and neurochemical effects of phosphatidylserine in MPTP lesion of the substantia nigra of rats.
Journal: European journal of pharmacology 20040126
Title: TorsinA, the gene linked to early-onset dystonia, is upregulated by the dopaminergic toxin MPTP in mice.
Journal: Neuroscience letters 20040123
Title: Avoidance of dyskinesia: preclinical evidence for continuous dopaminergic stimulation.
Journal: Neurology 20040113
Title: Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment.
Journal: Neurology 20040113
Title: Modafinil prevents the MPTP-induced increase in GABAA receptor binding in the internal globus pallidus of MPTP-treated common marmosets.
Journal: Neuroscience letters 20040102
Title: Differential effects of carboxyfullerene on MPP+/MPTP-induced neurotoxicity.
Journal: Neurochemistry international 20040101
Title: Glucocorticoid receptor deficiency increases vulnerability of the nigrostriatal dopaminergic system: critical role of glial nitric oxide.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040101
Title: Melatonin protects against oxidative stress caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the mouse nigrostriatum.
Journal: Journal of pineal research 20040101
Title: Depressed contractile function and adrenergic responsiveness of cardiac myocytes in an experimental model of Parkinson disease, the MPTP-treated mouse.
Journal: Neurobiology of aging 20040101
Title: Estrogen interacts with the IGF-1 system to protect nigrostriatal dopamine and maintain motoric behavior after 6-hydroxdopamine lesions.
Journal: Journal of neuroscience research 20040101
Title: Neurochemical and behavioural changes in zebrafish Danio rerio after systemic administration of 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Journal of neurochemistry 20040101
Title: Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation.
Journal: Journal of neurochemistry 20040101
Title: MPTP potentiates 3-nitropropionic acid-induced striatal damage in mice: reference to striatonigral degeneration.
Journal: Experimental neurology 20040101
Title: (-)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties.
Journal: Neurotoxicology 20040101
Title: Tobacco leaf, smoke and smoking, MAO inhibitors, Parkinson's disease and neuroprotection; are there links?
Journal: Neurotoxicology 20040101
Title: Characterization of novel dihydrothienopyridinium and thienopyridinium metabolites of ticlopidine in vitro: role of peroxidases, cytochromes p450, and monoamine oxidases.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040101
Title: Disruption of self-organized actions in monkeys with progressive MPTP-induced parkinsonism. I. Effects of task complexity.
Journal: The European journal of neuroscience 20040101
Title: Disruption of self-organized actions in monkeys with progressive MPTP-induced parkinsonism: II. Effects of reward preference.
Journal: The European journal of neuroscience 20040101
Title: The monoamine reuptake inhibitor BTS 74 398 fails to evoke established dyskinesia but does not synergise with levodopa in MPTP-treated primates.
Journal: Movement disorders : official journal of the Movement Disorder Society 20040101
Title: Neurogenesis in olfactory bulb identified by retroviral labeling in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated adult mice.
Journal: Neuroscience 20040101
Title: Time-course evaluation of whole blood phagocytosis in mice treated with the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Inflammopharmacology 20040101
Title: Matrix metalloproteinase-9 is elevated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
Journal: Neuromolecular medicine 20040101
Title: [Estimation of the protective effect of the novel potential antiparkinsonian agent himantane against MPTP neurotoxicity].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20040101
Title: Effects of high frequency deep brain stimulation on urine storage and voiding function in conscious minipigs.
Journal: Neurourology and urodynamics 20040101
Title: Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats.
Journal: BMC neurology 20040101
Title: Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists.
Journal: Neurotoxicity research 20040101
Title: [Comparative study of neurophysiological effects of adamantane derivatives in the experimental parkinsonism model].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20040101
Title: Decreased expression of kynurenine aminotransferase-I (KAT-I) in the substantia nigra of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment.
Journal: Neuroscience 20040101
Title: Identification of brain-derived neurotrophic factor in nestin-expressing astroglial cells in the neostriatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.
Journal: Neuroscience 20040101
Title: Dopamine transporter as a marker of neuroprotection in methamphetamine-lesioned mice treated acutely with estradiol.
Journal: Neuroendocrinology 20040101
Title: Selective recovery of striatal 125I-alpha-conotoxinmii nicotinic receptors after nigrostriatal damage in monkeys.
Journal: Neuroscience 20040101
Title: The strong inhibition of triosephosphate isomerase by the natural beta-carbolines may explain their neurotoxic actions.
Journal: Neuroscience 20040101
Title: Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment.
Journal: Neuroscience 20040101
Title: Sensitivity of zebrafish to environmental toxins implicated in Parkinson's disease.
Journal: Neurotoxicology and teratology 20040101
Title: Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D3 receptor.
Journal: BMC biology 20040101
Title: 1-amino-4-phenyl-1,2,3,6-tetrahydropyridine and 1-amino-4-phenylpyridinium salt, the 1-amino analogues of neurotoxins, MPTP and MPP+, induce apoptosis in PC12 cells: detection of apoptotic cells by Comet assay and flow cytometric analysis.
Journal: In vivo (Athens, Greece) 20040101
Title: Neuroprotective role of testosterone in the nervous system.
Journal: Polish journal of pharmacology 20040101
Title: Neuroprotective effects of phenylbutyrate against MPTP neurotoxicity.
Journal: Neuromolecular medicine 20040101
Title: Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate.
Journal: Journal of molecular neuroscience : MN 20040101
Title: MPTP-induced increase in c-Fos- and c-Jun-like immunoreactivity in the monkey cerebellum.
Journal: European journal of histochemistry : EJH 20040101
Title: Neuroprotective effects of oral administration of triacetyluridine against MPTP neurotoxicity.
Journal: Neuromolecular medicine 20040101
Title: Caenorhabditis elegans MPP+ model of Parkinson's disease for high-throughput drug screenings.
Journal: Neuro-degenerative diseases 20040101
Title: Injury and strain-dependent dopaminergic neuronal degeneration in the substantia nigra of mice after axotomy or MPTP.
Journal: Brain research 20031224
Title: Manganese complexes of curcumin and its derivatives: evaluation for the radical scavenging ability and neuroprotective activity.
Journal: Free radical biology & medicine 20031215
Title: Heat shock protects PC12 cells against MPP+ toxicity.
Journal: Brain research 20031212
Title: Modulation of GABAergic transmission in the striatopallidal system by adenosine A2A receptors: a potential mechanism for the antiparkinsonian effects of A2A antagonists.
Journal: Neurology 20031209
Title: Neuroprotection by caffeine and more specific A2A receptor antagonists in animal models of Parkinson's disease.
Journal: Neurology 20031209
Title: Monoamine oxidase B inhibition and neuroprotection: studies on selective adenosine A2A receptor antagonists.
Journal: Neurology 20031209
Title: Translating A2A antagonist KW6002 from animal models to parkinsonian patients.
Journal: Neurology 20031209
Title: Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031203
Title: Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine.
Journal: The Journal of pharmacology and experimental therapeutics 20031201
Title: Opioid antagonists increase the dyskinetic response to dopaminergic agents in parkinsonian monkeys: interaction between dopamine and opioid systems.
Journal: Neuropharmacology 20031201
Title: Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice.
Journal: Pharmacology, biochemistry, and behavior 20031201
Title: Survival and differentiation of transplanted neural stem cells in mice brain with MPTP-induced Parkinson disease.
Journal: Acta pharmacologica Sinica 20031201
Title: Chronic treatment with small doses of cabergoline prevents dopa-induced dyskinesias in parkinsonian monkeys.
Journal: Movement disorders : official journal of the Movement Disorder Society 20031201
Title: Inactivation of acetylcholinesterase by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride.
Journal: Molecular and cellular biochemistry 20031201
Title: Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease.
Journal: Molecular neurobiology 20031201
Title: Microglial response is poorly correlated with neurodegeneration following chronic, low-dose MPTP administration in monkeys.
Journal: Experimental neurology 20031201
Title: Diverse psychotomimetics act through a common signaling pathway.
Journal: Science (New York, N.Y.) 20031121
Title: Synthesis and in vitro biological evaluation of fluoro-substituted-4-phenyl-1,2,3,6-tetrahydropyridines as monoamine oxidase B substrates.
Journal: Bioorganic & medicinal chemistry 20031117
Title: Development of levodopa-induced dyskinesias in parkinsonian monkeys may depend upon rate of symptom onset and/or duration of symptoms.
Journal: Brain research 20031114
Title: Brain-derived neurotrophic factor controls dopamine D3 receptor expression: therapeutic implications in Parkinson's disease.
Journal: European journal of pharmacology 20031107
Title: PDNF, a human parasite-derived mimic of neurotrophic factors, prevents caspase activation, free radical formation, and death of dopaminergic cells exposed to the Parkinsonism-inducing neurotoxin MPP+.
Journal: Brain research. Molecular brain research 20031106
Title: Synthesis and evaluation of chiral bicyclic proline FKBP12 ligands.
Journal: Bioorganic & medicinal chemistry letters 20031103
Title: Synthesis, molecular modeling and biological evaluation of aza-proline and aza-pipecolic derivatives as FKBP12 ligands and their in vivo neuroprotective effects.
Journal: Bioorganic & medicinal chemistry 20031103
Title: Behavioral changes are not directly related to striatal monoamine levels, number of nigral neurons, or dose of parkinsonian toxin MPTP in mice.
Journal: Neurobiology of disease 20031101
Title: Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration.
Journal: Annals of neurology 20031101
Title: A2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinson's disease.
Journal: Experimental neurology 20031101
Title: Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole.
Journal: Experimental neurology 20031101
Title: Neuroprotective actions of the ginseng extract G115 in two rodent models of Parkinson's disease.
Journal: Experimental neurology 20031101
Title: Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset.
Journal: Movement disorders : official journal of the Movement Disorder Society 20031101
Title: MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-kappaB signaling pathways.
Journal: Journal of neuropathology and experimental neurology 20031101
Title: COX-2-deficient mice are less prone to MPTP-neurotoxicity than wild-type mice.
Journal: Neuroreport 20031027
Title: [Increased DMT1 expression and iron content in MPTP-treated C57BL/6 mice].
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20031025
Title: Minocycline enhances MPTP toxicity to dopaminergic neurons.
Journal: Journal of neuroscience research 20031015
Title: The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagiline.
Journal: Biochemical pharmacology 20031015
Title: Hprt(CAG)146 mice: age of onset of behavioral abnormalities, time course of neuronal intranuclear inclusion accumulation, neurotransmitter marker alterations, mitochondrial function markers, and susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: The Journal of comparative neurology 20031013
Title: Time-course of the expression of inflammatory cytokines and matrix metalloproteinases in the striatum and mesencephalon of mice injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a dopaminergic neurotoxin.
Journal: Neuroscience letters 20031009
Title: 3,4-methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031008
Title: D-deprenyl protects nigrostriatal neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity.
Journal: Synapse (New York, N.Y.) 20031001
Title: Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001
Title: Synergistic dopaminergic neurotoxicity of MPTP and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001
Title: Cerebral alterations in a MPTP-mouse model of Parkinson's disease--an immunocytochemical study.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20031001
Title: Primate models of Parkinson's disease.
Journal: Experimental neurology 20031001
Title: Increased striatal pre-proenkephalin B expression is associated with dyskinesia in Parkinson's disease.
Journal: Experimental neurology 20031001
Title: Mapping of brain function after MPTP-induced neurotoxicity in a primate Parkinson's disease model.
Journal: NeuroImage 20031001
Title: Quantitative analysis of dopaminergic loss in relation to functional territories in MPTP-treated monkeys.
Journal: The European journal of neuroscience 20031001
Title: Dipeptide analog of neurotensin active site prevents the development of experimental Parkinson's syndrome in mice.
Journal: Bulletin of experimental biology and medicine 20031001
Title: NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons.
Journal: The Journal of biological chemistry 20030926
Title: The MPTP-treated primate as a model of motor complications in PD: primate model of motor complications.
Journal: Neurology 20030923
Title: Compromised reactive microgliosis in MPTP-lesioned IL-6 KO mice.
Journal: Brain research 20030919
Title: Determination of MPTP, a toxic impurity of pethidine.
Journal: Journal of pharmaceutical and biomedical analysis 20030915
Title: Attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity by the novel selective dopamine D3-receptor partial agonist FAUC 329 predominantly in the nucleus accumbens of mice.
Journal: Biochemical pharmacology 20030915
Title: D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease.
Journal: The Journal of clinical investigation 20030915
Title: Cigarette smoke and nicotine protect dopaminergic neurons against the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Parkinsonian toxin.
Journal: Brain research 20030912
Title: Chromosomal loci influencing the susceptibility to the parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030910
Title: Sympathetic innervation in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 20030901
Title: Dopaminergic cell death precedes iron elevation in MPTP-injected monkeys.
Journal: Free radical biology & medicine 20030901
Title: Cerebrospinal fluid 3,4-dihydroxyphenylacetic acid level after tolcapone administration as an indicator of nigrostriatal degeneration.
Journal: Experimental neurology 20030901
Title: Overlesioned hemiparkinsonian non human primate model: correlation between clinical, neurochemical and histochemical changes.
Journal: Frontiers in bioscience : a journal and virtual library 20030901
Title: Profiling genes related to mitochondrial function in mice treated with N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Biochemical and biophysical research communications 20030815
Title: Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms.
Journal: European journal of pharmacology 20030815
Title: Synthesis and antioxidant activity evaluation of novel antiparkinsonian agents, aminoadamantane derivatives of nitroxyl free radical.
Journal: Bioorganic & medicinal chemistry 20030805
Title: LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 20030801
Title: Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy).
Journal: Acta neuropathologica 20030801
Title: Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Journal: Neuropharmacology 20030801
Title: Antidyskinetic effect of magnesium sulfate in MPTP-lesioned monkeys.
Journal: Experimental neurology 20030801
Title: Effects of monoamine oxidase inhibitors on the diethyldithiocarbamate-induced enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in C57BL/6 mice.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030801
Title: Recovery of motor function and dopaminergic parameters in a mouse model of Parkinson's disease induced by co-administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030801
Title: Effect of manganese exposure on MPTP neurotoxicities.
Journal: Neurotoxicology 20030801
Title: Circadian determinations of cortisol, prolactin and melatonin in chronic methyl-phenyl-tetrahydropyridine-treated monkeys.
Journal: Neuroendocrinology 20030801
Title: Calcium channel agonist, (+/-)-Bay K8644, causes an immediate increase in the striatal 1-methyl-4-phenylpyridinium level following systemic administration of the dopaminergic neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, in Balb/c mice.
Journal: Neuroscience letters 20030731
Title: Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells.
Journal: Biochemical pharmacology 20030715
Title: The subtype-selective nicotinic acetylcholine receptor agonist SIB-1553A improves both attention and memory components of a spatial working memory task in chronic low dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 20030701
Title: Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease.
Journal: Endocrinology 20030701
Title: Models of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20030701
Title: Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs.
Journal: Nuclear medicine and biology 20030701
Title: Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor.
Journal: Journal of neurochemistry 20030701
Title: Alpha-1B adrenergic receptor knockout mice are protected against methamphetamine toxicity.
Journal: Journal of neurochemistry 20030701
Title: Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT.
Journal: NeuroImage 20030701
Title: Adult neural stem/progenitor cells in neurodegenerative repair.
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20030625
Title: MPTP-induced reactive oxygen species promote cell death through a gradual activation of caspase-3 without expression of GRP78/Bip as a preventive measure against ER stress in PC12 cells.
Journal: Life sciences 20030620
Title: Rapid reduction of ATP synthesis and lack of free radical formation by MPP+ in rat brain synaptosomes and mitochondria.
Journal: Brain research 20030613
Title: The retina as a novel in vivo model for studying the role of molecules of the Bcl-2 family in relation to MPTP neurotoxicity.
Journal: Neurochemical research 20030601
Title: Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function.
Journal: Nature medicine 20030601
Title: Compensatory regulation of striatal neuropeptide gene expression occurs before changes in metabolic activity of basal ganglia nuclei.
Journal: Neurobiology of disease 20030601
Title: Estradiol and dehydroepiandrosterone potentiate levodopa-induced locomotor activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine monkeys.
Journal: Endocrine 20030601
Title: Role of dopamine transporter against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice.
Journal: Metabolic brain disease 20030601
Title: The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease.
Journal: Annals of the New York Academy of Sciences 20030601
Title: COX-2 and neurodegeneration in Parkinson's disease.
Journal: Annals of the New York Academy of Sciences 20030601
Title: Peroxynitrite and mitochondrial dysfunction in the pathogenesis of Parkinson's disease.
Journal: Antioxidants & redox signaling 20030601
Title: [New aspects of neuroprotective effects of nonsteroidal anti-inflammatory drugs].
Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20030601
Title: Interactions between environmental and genetic factors in the pathophysiology of Parkinson's disease.
Journal: IUBMB life 20030601
Title: Nitric oxide and reactive oxygen species in Parkinson's disease.
Journal: IUBMB life 20030601
Title: Dextromethorphan prevents the diethyldithiocarbamate enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in mice.
Journal: Brain research 20030530
Title: Differential expression patterns of mGluR1 alpha in monkey nigral dopamine neurons.
Journal: Neuroreport 20030523
Title: Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515
Title: Human neural stem cell transplantation in the MPTP-lesioned mouse.
Journal: Brain research 20030509
Title: Neuroprotective effect of vasoactive intestinal peptide (VIP) in a mouse model of Parkinson's disease by blocking microglial activation.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501
Title: Expression of S-100 protein is related to neuronal damage in MPTP-treated mice.
Journal: Glia 20030501
Title: Evidence for the substantia nigra pars compacta as an essential component of a memory system independent of the hippocampal memory system.
Journal: Neurobiology of learning and memory 20030501
Title: Influence of lipophilicity on the interactions of N-alkyl-4-phenyl-1,2,3,6-tetrahydropyridines and their positively charged N-alkyl-4-phenylpyridinium metabolites with cytochrome P450 2D6.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20030501
Title: Differential declines in striatal nicotinic receptor subtype function after nigrostriatal damage in mice.
Journal: Molecular pharmacology 20030501
Title: Rest tremor in rhesus monkeys with MPTP-induced parkinsonism.
Journal: Frontiers in bioscience : a journal and virtual library 20030501
Title: Increased synaptosomal dopamine content and brain concentration of paraquat produced by selective dithiocarbamates.
Journal: Journal of neurochemistry 20030501
Title: Effect of pulsatile administration of levodopa on dyskinesia induction in drug-naïve MPTP-treated common marmosets: effect of dose, frequency of administration, and brain exposure.
Journal: Movement disorders : official journal of the Movement Disorder Society 20030501
Title: Targeting programmed cell death in neurodegenerative diseases.
Journal: Nature reviews. Neuroscience 20030501
Title: Dietary restriction does not protect the nigrostriatal dopaminergic pathway of older animals from low-dose MPTP-induced neurotoxicity.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20030501
Title: Protection of dopaminergic neurons with a novel astrocyte modulating agent (R)-(-)-2-propyloctanoic acid (ONO-2506) in an MPTP-mouse model of Parkinson's disease.
Journal: Journal of the neurological sciences 20030415
Title: Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415
Title: Alterations in m-RNA expression for Cu,Zn-superoxide dismutase and glutathione peroxidase in the basal ganglia of MPTP-treated marmosets and patients with Parkinson's disease.
Journal: Brain research 20030411
Title: Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease.
Journal: Toxicology letters 20030404
Title: Inhibition of monoamine oxidase B by selective adenosine A2A receptor antagonists.
Journal: Bioorganic & medicinal chemistry 20030403
Title: Glutaredoxin is essential for maintenance of brain mitochondrial complex I: studies with MPTP.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401
Title: Prospects for antiapoptotic drug therapy of neurodegenerative diseases.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20030401
Title: 1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3.
Journal: Journal of neurochemistry 20030401
Title: Protective action of recombinant neurturin on dopaminergic neurons in substantia nigra in a rhesus monkey model of Parkinson's disease.
Journal: Neurological research 20030401
Title: Repeated estradiol treatment prevents MPTP-induced dopamine depletion in male mice.
Journal: Neuroendocrinology 20030401
Title: Ironic fate: can a banned drug control metal heavies in neurodegenerative diseases?
Journal: Neuron 20030327
Title: Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease.
Journal: Neuron 20030327
Title: Grid performance test to measure behavioral impairment in the MPTP-treated-mouse model of parkinsonism.
Journal: Journal of neuroscience methods 20030315
Title: Pattern of levodopa-induced striatal changes is different in normal and MPTP-lesioned mice.
Journal: Journal of neurochemistry 20030301
Title: Stimulation of the subthalamic nucleus changes the firing pattern of pallidal neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301
Title: Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice.
Journal: Neurobiology of disease 20030301
Title: Acute and subchronic MPTP administration differentially affects striatal glutamate synaptic function.
Journal: Experimental neurology 20030301
Title: Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice.
Journal: Brain research 20030227
Title: The establishment of a reliable cytotoxic system with SK-N-SH neuroblastoma cell culture.
Journal: Journal of neuroscience methods 20030215
Title: D-(+)-glucose rescue against 1-methyl-4-phenylpyridinium toxicity through anaerobic glycolysis in neuroblastoma cells.
Journal: Brain research 20030207
Title: PF 9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine], a new MAO-B inhibitor, attenuates MPTP-induced depletion of striatal dopamine levels in C57/BL6 mice.
Journal: Neurochemistry international 20030201
Title: Pathogenic role of glial cells in Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20030201
Title: Effects of some antioxidative aporphine derivatives on striatal dopaminergic transmission and on MPTP-induced striatal dopamine depletion in B6CBA mice.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030201
Title: Proton magnetic resonance imaging and spectroscopy identify metabolic changes in the striatum in the MPTP feline model of parkinsonism.
Journal: Experimental neurology 20030201
Title: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine pretreatment attenuates methamphetamine-induced dopamine toxicity.
Journal: Pharmacology & toxicology 20030201
Title: Dehydroepiandrosterone (DHEA) such as 17beta-estradiol prevents MPTP-induced dopamine depletion in mice.
Journal: Synapse (New York, N.Y.) 20030101
Title: Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.
Journal: Archives of biochemistry and biophysics 20030101
Title: Screening of novel pentacyclo-undecylamines for neuroprotective activity.
Journal: European journal of pharmacology 20030101
Title: Both short- and long-acting D-1/D-2 dopamine agonists induce less dyskinesia than L-DOPA in the MPTP-lesioned common marmoset (Callithrix jacchus).
Journal: Experimental neurology 20030101
Title: Experimental parkinsonism is associated with increased pallidal GAD gene expression and is reversed by site-directed antisense gene therapy.
Journal: Movement disorders : official journal of the Movement Disorder Society 20030101
Title: The mouse MPTP model: gene expression changes in dopaminergic neurons.
Journal: The European journal of neuroscience 20030101
Title: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced lipid peroxidation and DNA damage in mouse bone marrow and blood.
Journal: Environmental and molecular mutagenesis 20030101
Title: In vivo imaging of brain dopaminergic neurotransmission system in small animals with high-resolution single photon emission computed tomography.
Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030101
Title: Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: a link through mitochondrial dysfunction.
Journal: Journal of neurochemistry 20030101
Title: The contribution of the MPTP-treated primate model to the development of new treatment strategies for Parkinson's disease.
Journal: Parkinsonism & related disorders 20030101
Title: Synergistic effects of melatonin and deprenyl against MPTP-induced mitochondrial damage and DA depletion.
Journal: Neurobiology of aging 20030101
Title: Neuroprotective effects of inhibitors of dipeptidyl peptidase-iV in vitro and in vivo.
Journal: Advances in experimental medicine and biology 20030101
Title: Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice.
Journal: Neuroscience 20030101
Title: [Immunization of rats with bovine serum albumin conjugate with dopamine or 5-hydroxytryptamine prevents the development of experimental MPTP-induced depressive syndrome. An electrophysiological study].
Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20030101
Title: [Insufficiency of nigrostriatal dopaminergic system as a disregulation mechanism of dopamine-dependent depression syndrome].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101
Title: Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease.
Journal: Neuroscience 20030101
Title: Effects of acute administration of DA agonists on locomotor activity: MPTP versus neonatal intracerebroventricular 6-OHDA treatment.
Journal: Neurotoxicity research 20030101
Title: A chemical genetic approach for the identification of direct substrates of protein kinases.
Journal: Methods in molecular biology (Clifton, N.J.) 20030101
Title: BP 897, a selective dopamine D3 receptor ligand with therapeutic potential for the treatment of cocaine-addiction.
Journal: CNS drug reviews 20030101
Title: Neuroprotective strategies in Parkinson's disease : an update on progress.
Journal: CNS drugs 20030101
Title: What have we learnt from CDNA microarray gene expression studies about the role of iron in MPTP induced neurodegeneration and Parkinson's disease?
Journal: Journal of neural transmission. Supplementum 20030101
Title: Animal models of Parkinson's disease in rodents induced by toxins: an update.
Journal: Journal of neural transmission. Supplementum 20030101
Title: Experimental study on the protective effect of puerarin to Parkinson disease.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20030101
Title: Neurobehavioural deficits following postnatal iron overload: I spontaneous motor activity.
Journal: Neurotoxicity research 20030101
Title: Additive neuroprotective effects of creatine and a cyclooxygenase 2 inhibitor against dopamine depletion in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.
Journal: Journal of molecular neuroscience : MN 20030101
Title: Noradrenergic drugs for levodopa-induced dyskinesia.
Journal: Clinical neuropharmacology 20030101
Title: Overexpression of CYP2D6 attenuates the toxicity of MPP+ in actively dividing and differentiated PC12 cells.
Journal: Gene expression 20030101
Title: MPP(+)-induced degeneration is potentiated by dicoumarol in cultures of the RCSN-3 dopaminergic cell line. Implications of neuromelanin in oxidative metabolism of dopamine neurotoxicity.
Journal: Neurotoxicity research 20030101
Title: Green tea polyphenol (-)-epigallocatechin-3-gallate protects rat PC12 cells from apoptosis induced by serum withdrawal independent of P13-Akt pathway.
Journal: Neurotoxicity research 20030101
Title: Zinc potentiates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced dopamine depletion in caudate nucleus of mice brain.
Journal: Neuroscience letters 20021219
Title: Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys.
Journal: Neuroscience letters 20021219
Title: Dopamine, but not norepinephrine or serotonin, reuptake inhibition reverses motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates.
Journal: The Journal of pharmacology and experimental therapeutics 20021201
Title: Homocysteine, folate deficiency, and Parkinson's disease.
Journal: Nutrition reviews 20021201
Title: An inflammatory review of Parkinson's disease.
Journal: Progress in neurobiology 20021201
Title: [Genetics and environmental factors of Parkinson disease].
Journal: Revue neurologique 20021201
Title: Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease.
Journal: Brain research 20021122
Title: Impact of incorporating the 2C5 crystal structure into comparative models of cytochrome P450 2D6.
Journal: Proteins 20021101
Title: Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons.
Journal: Nature biotechnology 20021101
Title: 2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine].
Journal: The Journal of pharmacology and experimental therapeutics 20021101
Title: Declines in different beta2* nicotinic receptor populations in monkey striatum after nigrostriatal damage.
Journal: The Journal of pharmacology and experimental therapeutics 20021101
Title: Reversal of akinesia in experimental parkinsonism by GABA antagonist microinjections in the pedunculopontine nucleus.
Journal: Brain : a journal of neurology 20021101
Title: Disruption of the proprioceptive mapping in the medial wall of parkinsonian monkeys.
Journal: Annals of neurology 20021101
Title: p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism.
Journal: Annals of neurology 20021101
Title: Neural stem cells, scaffolds, and chaperones.
Journal: Nature biotechnology 20021101
Title: Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Experimental neurology 20021101
Title: Stimulation of cannabinoid receptors reduces levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20021101
Title: Beginning-of-dose and rebound worsening in MPTP-treated common marmosets treated with levodopa.
Journal: Movement disorders : official journal of the Movement Disorder Society 20021101
Title: Activation of the c-Jun N terminal kinase pathway in an animal model of Parkinson's disease.
Journal: Annals of the New York Academy of Sciences 20021101
Title: Neuroprotective effect of estradiol and phytoestrogens on MPP+-induced cytotoxicity in neuronal PC12 cells.
Journal: Journal of neuroscience research 20021001
Title: Increased vulnerability of dopaminergic neurons in MPTP-lesioned interleukin-6 deficient mice.
Journal: Journal of neurochemistry 20021001
Title: A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism.
Journal: Journal of neurochemistry 20021001
Title: Overexpression of Parkinson's disease-associated alpha-synucleinA53T by recombinant adeno-associated virus in mice does not increase the vulnerability of dopaminergic neurons to MPTP.
Journal: Journal of neurobiology 20021001
Title: Neuroimmunophilin ligand V-10,367 is neuroprotective after 24-hour delayed administration in a mouse model of diffuse traumatic brain injury.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20021001
Title: Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20021001
Title: [Pesticide exposure and Parkinson's syndrome - the epidemiological and experimental evidence].
Journal: Der Nervenarzt 20021001
Title: Role of nitric oxide synthase against MPTP neurotoxicity in mice.
Journal: Neurological research 20021001
Title: Environmental factors in Parkinson's disease.
Journal: Neurotoxicology 20021001
Title: Catecholaminergic neuronal degeneration in rainbow trout assessed by skin color change: a model system for identification of environmental risk factors.
Journal: Neurotoxicology 20021001
Title: Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells.
Journal: Neurotoxicology 20021001
Title: L-DOPA does not cause neurotoxicity in VMAT2 heterozygote knockout mice.
Journal: Neurotoxicology 20021001
Title: Quetiapine attenuates levodopa-induced motor complications in rodent and primate parkinsonian models.
Journal: Experimental neurology 20021001
Title: Early and late gene changes in MPTP mice model of Parkinson's disease employing cDNA microarray.
Journal: Neurochemical research 20021001
Title: 8-(3-Chlorostyryl)caffeine may attenuate MPTP neurotoxicity through dual actions of monoamine oxidase inhibition and A2A receptor antagonism.
Journal: The Journal of biological chemistry 20020927
Title: Dopamine replacement therapy reverses abnormal synchronization of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of parkinsonism.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915
Title: The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induces apoptosis in mouse nigrostriatal glia. Relevance to nigral neuronal death and striatal neurochemical changes.
Journal: The Journal of biological chemistry 20020913
Title: Dopamine reuptake inhibition and failure to evoke dyskinesia in MPTP-treated primates.
Journal: European journal of pharmacology 20020913
Title: Dopamine efflux by MPTP and hydroxyl radical generation.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020901
Title: Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020901
Title: Lack of effect of testosterone and dihydrotestosterone compared to 17beta-oestradiol in 1-methyl-4-phenyl-1,2,3,6, tetrahydropyridine-mice.
Journal: Journal of neuroendocrinology 20020901
Title: In vivo receptor assay with multiple ligand concentrations: an equilibrium approach.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020901
Title: Protective effect of ginsenoside Rg1 against MPTP-induced apoptosis in mouse substantia nigra neurons.
Journal: Acta pharmacologica Sinica 20020901
Title: Therapeutic effect of neuronal nitric oxide synthase inhibitor (7-nitroindazole) against MPTP neurotoxicity in mice.
Journal: Metabolic brain disease 20020901
Title: The monoamine reuptake blocker brasofensine reverses akinesia without dyskinesia in MPTP-treated and levodopa-primed common marmosets.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020901
Title: Repeated administration of piribedil induces less dyskinesia than L-dopa in MPTP-treated common marmosets: a behavioural and biochemical investigation.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020901
Title: The hyperkinetic abnormal movements scale: a tool for measuring levodopa-induced abnormal movements in squirrel monkeys.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020901
Title: Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate.
Journal: Neurotoxicology 20020901
Title: Role of TNF-alpha receptors in mice intoxicated with the parkinsonian toxin MPTP.
Journal: Experimental neurology 20020901
Title: Neuroprotective effect of the monoamine oxidase inhibitor PF 9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] on rat nigral neurons after 6-hydroxydopamine-striatal lesion.
Journal: Neuroscience letters 20020830
Title: GABA(A) and mu-opioid receptor binding in the globus pallidus and endopeduncular nucleus of animals symptomatic for and recovered from experimental Parkinsonism.
Journal: Brain research 20020830
Title: Pharmacological evaluation of a Br-76 analog of epibatidine: a potent ligand for studying brain nicotinic acetylcholine receptors.
Journal: Synapse (New York, N.Y.) 20020801
Title: Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects.
Journal: Journal of medicinal chemistry 20020801
Title: Synthesis of ketone analogues of prolyl and pipecolyl ester FKBP12 ligands.
Journal: Journal of medicinal chemistry 20020801
Title: Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease.
Journal: Journal of neurochemistry 20020801
Title: GABA-opioid interactions in the globus pallidus: [D-Ala2]-Met-enkephalinamide attenuates potassium-evoked GABA release after nigrostriatal lesion.
Journal: Journal of neurochemistry 20020801
Title: Studies on the oxidation of 1,4-disubstituted-1,2,3,6-tetrahydropyridines.
Journal: Drug metabolism reviews 20020801
Title: 1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) and related derivatives: chemistry and biochemical effects on catecholamine biosynthesis.
Journal: Bioorganic & medicinal chemistry 20020701
Title: Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811.
Journal: Molecular pharmacology 20020701
Title: Biodistribution study of [99mTc] TRODAT-1 alone or combined with other dopaminergic drugs in mice with macroautoradiography.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20020701
Title: Indomethacin protects against neurodegeneration caused by MPTP intoxication in mice.
Journal: International immunopharmacology 20020701
Title: Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615
Title: Role of hydroxyl radical formation in neurotoxicity as revealed by in vivo free radical trapping.
Journal: Toxicology letters 20020614
Title: Resistance to striatal dopamine depletion induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice expressing human mutant Cu,Zn superoxide dismutase.
Journal: Neuroscience letters 20020607
Title: Peroxynitrite inactivates the human dopamine transporter by modification of cysteine 342: potential mechanism of neurotoxicity in dopamine neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020601
Title: Enhanced synchrony among primary motor cortex neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020601
Title: Morphological and biochemical evidence that apomorphine rescues striatal dopamine terminals and prevents methamphetamine toxicity.
Journal: Annals of the New York Academy of Sciences 20020601
Title: Calpain upregulation and neuron death in spinal cord of MPTP-induced parkinsonism in mice.
Journal: Annals of the New York Academy of Sciences 20020601
Title: Effect of MPTP on Dopamine metabolism in Ames dwarf mice.
Journal: Neurochemical research 20020601
Title: Effect of tomato intake on striatal monoamine level in a mouse model of experimental Parkinson's disease.
Journal: Journal of nutritional science and vitaminology 20020601
Title: Experimental depressive-pain syndrome in rats with initial various anxiety-phobic levels: a behavioral study.
Journal: Bulletin of experimental biology and medicine 20020601
Title: The lesion of the rat substantia nigra pars compacta dopaminergic neurons as a model for Parkinson's disease memory disabilities.
Journal: Cellular and molecular neurobiology 20020601
Title: Effects of fibroblast growth factor and glial-derived neurotrophic factor on akinesia, F-DOPA uptake and dopamine cells in parkinsonian primates.
Journal: Parkinsonism & related disorders 20020601
Title: Solid-phase synthesis of FKBP12 inhibitors: N-sulfonyl and N-carbamoylprolyl/pipecolyl amides.
Journal: Bioorganic & medicinal chemistry letters 20020520
Title: Biochemical and pharmacological characterization of 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline: a biologically relevant neurotoxin?
Journal: European journal of pharmacology 20020503
Title: Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice.
Journal: Experimental neurology 20020501
Title: Environmental estrogen-like chemicals and hydroxyl radicals induced by MPTP in the striatum: a review.
Journal: Neurochemical research 20020501
Title: Modification of tyrosine hydroxylase activity by chloral derived beta-carbolines in vitro.
Journal: Journal of neurochemistry 20020501
Title: Nitric oxide: an antioxidant and neuroprotector.
Journal: Annals of the New York Academy of Sciences 20020501
Title: Impaired learning in a spatial working memory version and in a cued version of the water maze in rats with MPTP-induced mesencephalic dopaminergic lesions.
Journal: Brain research bulletin 20020501
Title: Animal models of Parkinson's disease.
Journal: BioEssays : news and reviews in molecular, cellular and developmental biology 20020401
Title: Dopaminergic cells of the carotid body: physiological significance and possible therapeutic applications in Parkinson's disease.
Journal: Brain research bulletin 20020401
Title: Method for culturing postnatal substantia nigra as an in vitro model of experimental Parkinson's disease.
Journal: Brain research. Brain research protocols 20020401
Title: Age-related alteration in hepatic disposition of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and pesticides.
Journal: Pharmacology & toxicology 20020401
Title: [Possible mechanisms of the protective effect of ginsenoside Rg1 on apoptosis in substantia nigra neurons].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020401
Title: Antioxidant compounds protect dopamine neurons from death due to oxidative stress in vitro.
Journal: Brain research 20020329
Title: Caffeine's neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity shows no tolerance to chronic caffeine administration in mice.
Journal: Neuroscience letters 20020329
Title: Association of homozygous 7048G7049 variant in the intron six of Nurr1 gene with Parkinson's disease.
Journal: Neurology 20020326
Title: Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro.
Journal: Neuroscience letters 20020315
Title: Thioredoxin suppresses 1-methyl-4-phenylpyridinium-induced neurotoxicity in rat PC12 cells.
Journal: Neuroscience letters 20020315
Title: The distribution of copper, zinc- and manganese-superoxide dismutase, and glutathione peroxidase messenger ribonucleic acid in rat basal ganglia.
Journal: Biochemical pharmacology 20020315
Title: Striatal AMPA receptor binding is unaltered in the MPTP-lesioned macaque model of Parkinson's disease and dyskinesia.
Journal: Experimental neurology 20020301
Title: Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301
Title: Continuous subcutaneous infusion of apomorphine rescues nigro-striatal dopaminergic terminals following MPTP injection in mice.
Journal: Neuropharmacology 20020301
Title: Selective dopaminergic neurotoxicity of isoquinoline derivatives related to Parkinson's disease: studies using heterologous expression systems of the dopamine transporter.
Journal: Biochemical pharmacology 20020301
Title: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine has a transient proliferative effect on PC12h cells and nerve growth factor additively promotes this effect: possible involvement of distinct mechanisms of activation of MAP kinase family proteins.
Journal: Brain research. Developmental brain research 20020227
Title: Pharmacology of dopamine agonists in the treatment of Parkinson's disease.
Journal: Neurology 20020226
Title: Neuroprotection and dopamine agonists.
Journal: Neurology 20020226
Title: Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.
Journal: Human gene therapy 20020210
Title: Effects of the prolyl endopeptidase inhibitor S 17092 on cognitive deficits in chronic low dose MPTP-treated monkeys.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020201
Title: Neuroprotective actions of selegiline.
Journal: Journal of neuroscience research 20020201
Title: Slow oscillatory discharge in the primate basal ganglia.
Journal: Journal of neurophysiology 20020201
Title: Significant reduction of 125 I-meta-iodobenzylguanidine accumulation directly caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine, a toxic agent for inducing experimental Parkinson's disease.
Journal: Nuclear medicine communications 20020201
Title: The actions of a D-1 agonist in MPTP treated primates show dependence on both D-1 and D-2 receptor function and tolerance on repeated administration.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020201
Title: Disturbances of saccadic eye movements in monkeys during development of MPTP-induced syndrome.
Journal: Bulletin of experimental biology and medicine 20020201
Title: Deprenyl protects from MPTP-induced Parkinson-like syndrome and glutathione oxidation in rat striatum.
Journal: Toxicology 20020125
Title: Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease.
Journal: The Journal of comparative neurology 20020121
Title: Significant up-regulation of nestin protein in the neostriatum of MPTP-treated mice. Are the striatal astrocytes regionally activated after systemic MPTP administration?
Journal: Brain research 20020118
Title: Effects of transient focal inactivation of the basal ganglia in parkinsonian primates.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020115
Title: Loss of nicotinic receptors in monkey striatum after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment is due to a decline in alpha-conotoxin MII sites.
Journal: Molecular pharmacology 20020101
Title: Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease.
Journal: Journal of neurochemistry 20020101
Title: Neuroprotective effect of riluzole in a primate model of Parkinson's disease: behavioral and histological evidence.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020101
Title: Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical.
Journal: Journal of pineal research 20020101
Title: Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020101
Title: Neuroprotection by adenosine A2A receptor blockade in experimental models of Parkinson's disease.
Journal: Journal of neurochemistry 20020101
Title: Differential vulnerability of snake species to MPTP: a behavioral and biochemical comparison in ratsnakes (Elaphe) and watersnakes (Nerodia).
Journal: Neurotoxicology and teratology 20020101
Title: Brainstem motor loops in the control of movement.
Journal: Movement disorders : official journal of the Movement Disorder Society 20020101
Title: [Experimental models of Parkinson's disease].
Journal: Annales pharmaceutiques francaises 20020101
Title: Differential nicotinic receptor expression in monkey basal ganglia: effects of nigrostriatal damage.
Journal: Neuroscience 20020101
Title: Increases in striatal preproenkephalin gene expression are associated with nigrostriatal damage but not L-DOPA-induced dyskinesias in the squirrel monkey.
Journal: Neuroscience 20020101
Title: Amine-related neurotoxins in Parkinson's disease: past, present, and future.
Journal: Neurotoxicology and teratology 20020101
Title: N-methylation underlying Parkinson's disease.
Journal: Neurotoxicology and teratology 20020101
Title: Apoptotic molecules and MPTP-induced cell death.
Journal: Neurotoxicology and teratology 20020101
Title: MPTP: insights into parkinsonian neurodegeneration.
Journal: Neurotoxicology and teratology 20020101
Title: Aliphatic propargylamines as symptomatic and neuroprotective treatments for neurodegenerative diseases.
Journal: Neurotoxicology and teratology 20020101
Title: Parkinson's disease.
Journal: International review of neurobiology 20020101
Title: Exploration of the role of the upper brainstem in motor control.
Journal: Stereotactic and functional neurosurgery 20020101
Title: Elevation of antioxidant potency in mice brain by low-dose X-ray irradiation and its effect on Fe-NTA-induced brain damage.
Journal: Physiological chemistry and physics and medical NMR 20020101
Title: Endogenous risk factors in Parkinson's disease: dopamine and tetrahydroisoquinolines.
Journal: Polish journal of pharmacology 20020101
Title: Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011215
Title: Mutation analysis of the human NR4A2 gene, an essential gene for midbrain dopaminergic neurogenesis, in schizophrenic patients.
Journal: American journal of medical genetics 20011208
Title: Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway.
Journal: Brain research 20011207
Title: Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Journal: Neuroscience letters 20011201
Title: Protective effect and mechanism of Ginkgo biloba leaf extracts for Parkinson disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Acta pharmacologica Sinica 20011201
Title: L-Dopa restores striatal dopamine level but fails to reverse MPTP-induced memory deficits in rats.
Journal: The international journal of neuropsychopharmacology 20011201
Title: Neurotoxicity of MPTP.
Journal: Neuropathology : official journal of the Japanese Society of Neuropathology 20011201
Title: Increased cannabinoid CB1 receptor binding and activation of GTP-binding proteins in the basal ganglia of patients with Parkinson's syndrome and of MPTP-treated marmosets.
Journal: The European journal of neuroscience 20011201
Title: Profound astrogenesis in the striatum of adult mice following nigrostriatal dopaminergic lesion by repeated MPTP administration.
Journal: Brain research. Developmental brain research 20011126
Title: Cell membrane transport of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the liver and systemic bioavailability.
Journal: Biochemical and biophysical research communications 20011123
Title: Sequential up-regulation of the c-fos, c-jun and bax genes in the cortex, striatum and cerebellum induced by a single injection of a low dose of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in C57BL/6 mice.
Journal: Neuroscience letters 20011113
Title: Impairment of the neuronal dopamine transporter activity in MPP(+)-treated rat was not prevented by treatments with nitric oxide synthase or poly(ADP-ribose) polymerase inhibitors.
Journal: Neuroscience letters 20011113
Title: Neuroprotective effect of riluzole in MPTP-treated mice.
Journal: Brain research 20011109
Title: Nicotine administration reduces striatal MPP+ levels in mice.
Journal: Brain research 20011102
Title: Antiparkinsonian action of a delta opioid agonist in rodent and primate models of Parkinson's disease.
Journal: Experimental neurology 20011101
Title: Behavioral phenotyping of the MPTP mouse model of Parkinson's disease.
Journal: Behavioural brain research 20011101
Title: Evaluation of neurotoxicity of TIQ and MPTP and of parkinsonism-preventing effect of 1-MeTIQ by in vivo measurement of pre-synaptic dopamine transporters and post-synaptic dopamine D(2) receptors in the mouse striatum.
Journal: Journal of neurochemistry 20011101
Title: Differential effects of D1 and D2 agonists in MPTP-treated primates: functional implications for Parkinson's disease. 1990.
Journal: Neurology 20011101
Title: Acute exposure to organochlorine pesticides does not affect striatal dopamine in mice.
Journal: Neurotoxicity research 20011101
Title: Adenosine A(2a) receptor antagonists: potential therapeutic and neuroprotective effects in Parkinson's disease.
Journal: Neurotoxicity research 20011101
Title: Diversity in mechanisms of substrate oxidation by cytochrome P450 2D6. Lack of an allosteric role of NADPH-cytochrome P450 reductase in catalytic regioselectivity.
Journal: The Journal of biological chemistry 20011026
Title: Assessment of motor behavior using a video system and a clinical rating scale in parkinsonian monkeys lesioned by MPTP.
Journal: Journal of neuroscience methods 20011015
Title: Riluzole (2-amino-6-trifluoromethoxy benzothiazole) attenuates MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity in mice.
Journal: Neuroscience letters 20011012
Title: Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease.
Journal: Progress in neurobiology 20011001
Title: Molecular neurotoxicological models of Parkinsonism: focus on genetic manipulation of mice.
Journal: Parkinsonism & related disorders 20011001
Title: Lidocaine and muscimol microinjections in subthalamic nucleus reverse Parkinsonian symptoms.
Journal: Brain : a journal of neurology 20011001
Title: Memory disruption in rats with nigral lesions induced by MPTP: a model for early Parkinson's disease amnesia.
Journal: Behavioural brain research 20010928
Title: Manganese mimics the action of 1-methyl-4-phenylpyridinium ion, a dopaminergic neurotoxin, in rat striatal tissue slices.
Journal: Neuroscience letters 20010921
Title: Loss of metabolites from monkey striatum during PET with FDOPA.
Journal: Synapse (New York, N.Y.) 20010901
Title: The parkinsonian neurotoxin, MPP+ induces phosphorylated c-Jun in dopaminergric neurons of mesencephalic cultures.
Journal: Parkinsonism & related disorders 20010901
Title: Evidence for target-specific outgrowth from subpopulations of grafted human dopamine neurons.
Journal: Microscopy research and technique 20010901
Title: Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010901
Title: Mu- and delta-opioid receptor antagonists reduce levodopa-induced dyskinesia in the MPTP-lesioned primate model of Parkinson's disease.
Journal: Experimental neurology 20010901
Title: Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration.
Journal: Journal of neurochemistry 20010901
Title: 1-Methyl-4-phenyl-pyridinium increases S-adenosyl-L-methionine dependent phospholipid methylation.
Journal: Pharmacology, biochemistry, and behavior 20010901
Title: Novel observations with FDOPA-PET imaging after early nigrostriatal damage.
Journal: Movement disorders : official journal of the Movement Disorder Society 20010901
Title: Group I mGluR antagonist AIDA protects nigral DA cells from MPTP-induced injury.
Journal: Neuroreport 20010828
Title: Dissociated functional recovery in parkinsonian monkeys following transplantation of astroglial cells.
Journal: Brain research 20010824
Title: Nitric oxide enhances MPP(+) inhibition of complex I.
Journal: FEBS letters 20010824
Title: Interactions of 1-methyl-4-phenylpyridinium and other compounds with P-glycoprotein: relevance to toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Journal: Brain research 20010810
Title: Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice.
Journal: Synapse (New York, N.Y.) 20010801
Title: Protection of nigral neurons by GDNF-engineered marrow cell transplantation.
Journal: Neuroscience research 20010801
Title: Vulnerability of 125I-alpha-conotoxin MII binding sites to nigrostriatal damage in monkey.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010801
Title: Tyrosine hydroxylase and dopamine transporter expression in residual dopaminergic neurons: potential contributors to spontaneous recovery from experimental Parkinsonism.
Journal: Journal of neuroscience research 20010801
Title: Cytochrome P450 2D6.1 and cytochrome P450 2D6.10 differ in catalytic activity for multiple substrates.
Journal: Pharmacogenetics 20010801
Title: Neurotrophic and neuroprotective actions of ginsenosides Rb(1) and Rg(1).
Journal: Planta medica 20010801
Title: Biochemical and pathological study of endogenous 1-benzyl-1,2,3,4-tetrahydroisoquinoline-induced parkinsonism in the mouse.
Journal: Brain research 20010713
Title: Expression of striatal preprotachykinin mRNA in symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-exposed monkeys is related to parkinsonian motor signs.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701
Title: Differentiation of embryonic stem cell-derived dopaminergic neurons is enhanced by survival-promoting factors.
Journal: Mechanisms of development 20010701
Title: Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R-apomorphine.
Journal: Journal of neurochemistry 20010701
Title: Anatomic and biochemical correlates of the dopamine transporter ligand 11C-PE2I in normal and parkinsonian primates: comparison with 6-[18F]fluoro-L-dopa.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010701
Title: Neuroimmunophilins: novel neuroprotective and neuroregenerative targets.
Journal: Annals of neurology 20010701
Title: Antiparkinsonian activity and dyskinesia risk of ropinirole and L-DOPA combination therapy in drug naïve MPTP-lesioned common marmosets (Callithrix jacchus).
Journal: Movement disorders : official journal of the Movement Disorder Society 20010701
Title: Neural mechanisms underlying peak-dose dyskinesia induced by levodopa and apomorphine are distinct: evidence from the effects of the alpha(2) adrenoceptor antagonist idazoxan.
Journal: Movement disorders : official journal of the Movement Disorder Society 20010701
Title: Idazoxan, an alpha-2 antagonist, and L-DOPA-induced dyskinesias in patients with Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 20010701
Title: [Pathogenesis of idiopathic Parkinson's disease].
Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20010701
Title: Administration of FGF-1 through transfected cells alleviates MPTP toxicity in mice.
Journal: Neurotoxicity research 20010701
Title: Neuroprotective effects of pramipexole in young and aged MPTP-treated mice.
Journal: Brain research 20010629
Title: Changes in striatal dopamine D3 receptor regulation during expression of and recovery from MPTP-induced parkinsonism.
Journal: Brain research 20010629
Title: Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation.
Journal: Brain research 20010629
Title: Differential regulation of striatal G protein levels following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration in C57 BL/6 mice.
Journal: Neuroscience letters 20010622
Title: Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4).
Journal: Biochimica et biophysica acta 20010606
Title: Effect of MPTP-induced denervation on basal ganglia GABA(B) receptors: correlation with dopamine concentrations and dopamine transporter.
Journal: Synapse (New York, N.Y.) 20010601
Title: Parkinson's disease--redox mechanisms.
Journal: Current medicinal chemistry 20010601
Title: Lack of protective effect by intermittent hypoxia on MPTP-induced neurotoxicity in mice.
Journal: Annals of the New York Academy of Sciences 20010601
Title: Rescue of dying neurons by (R)-deprenyl in the MPTP-mouse model of Parkinson's disease does not include restoration of neostriatal dopamine.
Journal: Annals of the New York Academy of Sciences 20010601
Title: Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates.
Journal: Psychopharmacology 20010601
Title: Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010515
Title: Participation of manganese-superoxide dismutase in the neuroprotection exerted by copper sulfate against 1-methyl 4-phenylpyridinium neurotoxicity.
Journal: Brain research bulletin 20010515
Title: Experimental models of Parkinson's disease.
Journal: Nature reviews. Neuroscience 20010501
Title: Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice.
Journal: Journal of neurochemistry 20010501
Title: Caffeine reverses the memory disruption induced by intra-nigral MPTP-injection in rats.
Journal: Brain research bulletin 20010501
Title: Preclinical models of Parkinson's disease.
Journal: Current protocols in neuroscience 20010501
Title: Nuclear factor-kappaB activation is not involved in a MPTP model of Parkinson's disease.
Journal: Neuroreport 20010417
Title: Strain-dependent susceptibility to MPTP and MPP(+)-induced parkinsonism is determined by glia.
Journal: Glia 20010415
Title: Dose-dependent protective effects of apomorphine against methamphetamine-induced nigrostriatal damage.
Journal: Brain research 20010413
Title: Parkin immunoreactivity in the brain of human and non-human primates: an immunohistochemical analysis in normal conditions and in Parkinsonian syndromes.
Journal: The Journal of comparative neurology 20010402
Title: Neuroprotective effects of (+/-)-kavain in the MPTP mouse model of Parkinson's disease.
Journal: Synapse (New York, N.Y.) 20010401
Title: Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid.
Journal: Experimental neurology 20010401
Title: Selective inhibition of MAO-B through chronic low-dose (R)-deprenyl treatment in C57BL/6 mice has no effect on basal neostriatal dopamine levels.
Journal: Experimental neurology 20010401
Title: Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010401
Title: Effects of R- and S-apomorphine on MPTP-induced nigro-striatal dopamine neuronal loss.
Journal: Journal of neurochemistry 20010401
Title: Prosaptide D5, a retro-inverso 11-mer peptidomimetic, rescued dopaminergic neurons in a model of Parkinson's disease.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010401
Title: Upregulation of striatal preproenkephalin gene expression occurs before the appearance of parkinsonian signs in 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine monkeys.
Journal: Neurobiology of disease 20010401
Title: Protective role of melatonin against MPTP-induced mouse brain cell DNA fragmentation and apoptosis in vivo.
Journal: Neuro endocrinology letters 20010401
Title: Pharmacological properties of the MPTP analog trans-1-methyl-4-[4-dimethylaminophenylethenyl]-1,2,3,6-tetrahydropyridine and its pyridinium metabolite in mouse brain synaptosomes: a potential visual marker for substrates of MPTP-induced neurotoxicity.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20010401
Title: Serotonin 5-HT(1A) receptor expression is selectively enhanced in the striosomal compartment of chronic parkinsonian monkeys.
Journal: Synapse (New York, N.Y.) 20010315
Title: A new in vitro approach for investigating the MPTP effect on DA uptake.
Journal: Neurochemistry international 20010301
Title: Evidence for a dissociation between MPTP toxicity and tyrosinase activity based on congenic mouse strain susceptibility.
Journal: Experimental neurology 20010301
Title: Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys.
Journal: Experimental neurology 20010301
Title: Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey.
Journal: Brain : a journal of neurology 20010301
Title: Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease.
Journal: Journal of neuroscience research 20010301
Title: The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety.
Journal: Journal of neurochemistry 20010301
Title: Gene therapy to the rescue in Parkinson's disease. Response from Kordower and Aebischer.
Journal: Trends in pharmacological sciences 20010301
Title: Immunophilin ligands can prevent progressive dopaminergic degeneration in animal models of Parkinson's disease.
Journal: The European journal of neuroscience 20010301
Title: Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice.
Journal: Movement disorders : official journal of the Movement Disorder Society 20010301
Title: Reliability and validity of a new global dyskinesia rating scale in the MPTP-lesioned non-human primate.
Journal: Movement disorders : official journal of the Movement Disorder Society 20010301
Title: Eldepryl prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigral neuronal apoptosis in mice.
Journal: Chinese medical journal 20010301
Title: SKF-38393, a dopamine receptor agonist, attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity.
Journal: Brain research 20010223
Title: Erythropoietin exerts neuroprotection in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/BL mice via increasing nitric oxide production.
Journal: Neuroscience letters 20010202
Title: Nicotine, but not cotinine, partially protects dopaminergic neurons against MPTP-induced degeneration in mice.
Journal: Brain research 20010202
Title: Effects of acute and repeated treatment with a novel dopamine D2 receptor ligand on L-DOPA-induced dyskinesias in MPTP monkeys.
Journal: European journal of pharmacology 20010202
Title: Activity of pallidal and striatal tonically active neurons is correlated in mptp-treated monkeys but not in normal monkeys.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010201
Title: Protection from MPTP-induced neurotoxicity in differentiating mouse N2a neuroblastoma cells.
Journal: Journal of neurochemistry 20010201
Title: Antiparkinsonian and behavioral effects of inactivation of the substantia nigra pars reticulata in hemiparkinsonian primates.
Journal: Experimental neurology 20010201
Title: GDNF reverses priming for dyskinesia in MPTP-treated, L-DOPA-primed common marmosets.
Journal: The European journal of neuroscience 20010201
Title: Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism.
Journal: Journal of neurochemistry 20010201
Title: [Parkinsonism induced by MPTP and free radical generation].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010201
Title: Accumulation of the 1-methyl-4-phenylpyridinium ion in suncus (Suncus murinus) brain: implication for flavin-containing monooxygenase activity in brain microvessels.
Journal: Chemical research in toxicology 20010201
Title: Nicotinamide-N-methyltransferase is higher in the lumbar cerebrospinal fluid of patients with Parkinson's disease.
Journal: Neuroscience letters 20010126
Title: Glial cell line-derived neurotrophic factor concentration dependently improves disability and motor activity in MPTP-treated common marmosets.
Journal: European journal of pharmacology 20010119
Title: Molecular characterization of monoamine oxidases A and B.
Journal: Progress in nucleic acid research and molecular biology 20010101
Title: Biochemical and immunohistological changes in the brain of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mouse.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010101
Title: Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.
Journal: Experimental neurology 20010101
Title: Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP+-induced neurotoxicity along with brain-derived neurotrophic factor induction.
Journal: Journal of neurochemistry 20010101
Title: Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.
Journal: Journal of neurochemistry 20010101
Title: [Sensorimotor reactivity (acoustic startle response) in rats with experimental depressive syndrome].
Journal: Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20010101
Title: Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey.
Journal: Neuroscience 20010101
Title: Co-administration of memantine and amantadine with sub/suprathreshold doses of L-Dopa restores motor behaviour of MPTP-treated mice.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101
Title: Ubiquinone (coenzyme q10) and mitochondria in oxidative stress of parkinson's disease.
Journal: Biological signals and receptors 20010101
Title: [Mexidol potentiates antiparkinsonian effect of L-DOPA in MPTP-induced parkinsonism model].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101
Title: Microtubule assembly is directly affected by MPP(+)in vitro.
Journal: Cell biology international 20010101
Title: Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment.
Journal: Neuroscience 20010101
Title: Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101
Title: Effects of single and repeated administration of 1,2,3,4-tetrahydroisoquinoline analogs on the binding of [11C]raclopride to dopamine D2 receptors in the mouse brain.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101
Title: Neuronal ectopic expression of tyrosine hydroxylase in the mouse striatum by combined administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 3-nitropropionic acid.
Journal: Neuroscience 20010101
Title: Are dopamine, norepinephrine, and serotonin precursors of biologically reactive intermediates involved in the pathogenesis of neurodegenerative brain disorders?
Journal: Advances in experimental medicine and biology 20010101
Title: Neurochemical findings in the MPTP model of Parkinson's disease.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20010101
Title: Current evidence for neuroprotective effects of nicotine and caffeine against Parkinson's disease.
Journal: Drugs & aging 20010101
Title: Neurotoxicology of the brain barrier system: new implications.
Journal: Journal of toxicology. Clinical toxicology 20010101
Title: Complex I and Parkinson's disease.
Journal: IUBMB life 20010101
Title: [Treatment of neurodegenerative diseases: new perspectives].
Journal: Neurologia i neurochirurgia polska 20010101
Title: Apomorphine as a neuroprotective drug: a study in MPTP-treated mice and potential relevance to ischemia.
Journal: Functional neurology 20010101
Title: Experimental parkinsonism in primates.
Journal: Stereotactic and functional neurosurgery 20010101
Title: The role of the pedunculopontine tegmental nucleus in experimental parkinsonism in primates.
Journal: Stereotactic and functional neurosurgery 20010101
Title: Oxidative stress indices in Parkinson's disease : biochemical determination.
Journal: Methods in molecular medicine 20010101
Title: Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model.
Journal: Movement disorders : official journal of the Movement Disorder Society 20000501
Title: AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys.
Journal: Neurology 20000425
Title: Combined use of the adenosine A(2A) antagonist KW-6002 with L-DOPA or with selective D1 or D2 dopamine agonists increases antiparkinsonian activity but not dyskinesia in MPTP-treated monkeys.
Journal: Experimental neurology 20000401
Title: Investigating levodopa-induced dyskinesias in the parkinsonian primate.
Journal: Annals of neurology 20000401
Title: Effects of the partial glycine agonist D-cycloserine on cognitive functioning in chronic low dose MPTP-treated monkeys.
Journal: Brain research 20000331
Title: Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20000201
Title: Sustained cabergoline treatment reverses levodopa-induced dyskinesias in parkinsonian monkeys.
Journal: Clinical neuropharmacology 20000101
Title: Neuroprotective effects of estrogen upon the nigrostriatal dopaminergic system.
Journal: Journal of neurocytology 20000101
Title: Internal globus pallidus discharge is nearly suppressed during levodopa-induced dyskinesias.
Journal: Annals of neurology 19991101
Title: Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP.
Journal: Psychopharmacology 19991101
Title: The alpha2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances anti-parkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease.
Journal: Movement disorders : official journal of the Movement Disorder Society 19990901
Title: D1 receptor blockade improves L-dopa-induced dyskinesia but worsens parkinsonism in MPTP monkeys.
Journal: Neurology 19990310
Title: CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.
Journal: The Journal of pharmacology and experimental therapeutics 19990201
Title: Differential regulation of striatal preproenkephalin and preprotachykinin mRNA levels in MPTP-lesioned monkeys chronically treated with dopamine D1 or D2 receptor agonists.
Journal: Journal of neurochemistry 19990201
Title: Nicotine prevents experimental parkinsonism in rodents and induces striatal increase of neurotrophic factors.
Journal: Journal of neurochemistry 19981201
Title: Effects of pramipexole on contraversive rotation and functional motor impairments in 1-methyl-4-phenyl1,2,3, 6-tetrahydropyridine-induced chronic hemiparkinsonian monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 19981201
Title: Amantadine reduces levodopa-induced dyskinesias in parkinsonian monkeys.
Journal: Movement disorders : official journal of the Movement Disorder Society 19980901
Title: Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys.
Journal: Annals of neurology 19970801
Title: Potential therapeutic use of the selective dopamine D1 receptor agonist, A-86929: an acute study in parkinsonian levodopa-primed monkeys.
Journal: Neurology 19970801
Title: (-)-OSU 6162 inhibits levodopa-induced dyskinesias in a monkey model of Parkinson's disease.
Journal: Neuroreport 19970728
Title: The selective dopamine D1 receptor agonist A-86929 maintains efficacy with repeated treatment in rodent and primate models of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 19970401
Title: Striatal increase of neurotrophic factors as a mechanism of nicotine protection in experimental parkinsonism.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 19970101
Title: Effects of L-DOPA-therapy on dopamine D2 receptor mRNA expression in the striatum of MPTP-intoxicated parkinsonian monkeys.
Journal: Brain research. Molecular brain research 19961101
Title: Poly(ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice.
Journal: Brain research 19960812
Title: Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys.
Journal: Annals of neurology 19960501
Title: Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of deltaFosB-like protein(s) in both the rodent and primate striatum.
Journal: The European journal of neuroscience 19960201
Title: ABT-431: the diacetyl prodrug of A-86929, a potent and selective dopamine D1 receptor agonist: in vitro characterization and effects in animal models of Parkinson's disease.
Journal: The Journal of pharmacology and experimental therapeutics 19960101
Title: Chronic L-DOPA administration induces dyskinesias in the 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine-treated common marmoset (Callithrix Jacchus).
Journal: Movement disorders : official journal of the Movement Disorder Society 19951101
Title: Levodopa or D2 agonist induced dyskinesia in MPTP monkeys: correlation with changes in dopamine and GABAA receptors in the striatopallidal complex.
Journal: Brain research 19950522
Title: Behavioral involvement of central dopamine D1 and D2 receptors in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned parkinsonian cynomolgus monkeys.
Journal: Japanese journal of pharmacology 19950201
Title: Is striatal dopaminergic receptor imbalance responsible for levodopa-induced dyskinesia?
Journal: Fundamental & clinical pharmacology 19950101
Title: Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.
Journal: The Journal of pharmacology and experimental therapeutics 19941201
Title: Excitotoxic lateral pallidotomy does not relieve L-dopa-induced dyskinesia in MPTP parkinsonian monkeys.
Journal: Brain research 19940704
Title: Dopamine-depleting effects of MPTP and reserpine in weaver mutant mice.
Journal: Molecular and chemical neuropathology 19931201
Title: Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys.
Journal: Clinical neuropharmacology 19931001
Title: Thalamotomy for the alleviation of levodopa-induced dyskinesia: experimental studies in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated parkinsonian monkey.
Journal: Neuroscience 19930701
Title: Effects of terguride, a partial D2 agonist, on MPTP-lesioned parkinsonian cynomolgus monkeys.
Journal: Annals of neurology 19930501
Title: Dystonia induced by combined treatment with L-dopa and MK-801 in parkinsonian monkeys.
Journal: Annals of neurology 19920701
Title: [Dopa-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated hemiparkinsonian monkeys].
Journal: Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry 19920201
Title: Effect of ethosuximide on rest tremor in the MPTP monkey model.
Journal: Movement disorders : official journal of the Movement Disorder Society 19920101
Title: Quantitative structure-metabolism relationship analyses of MAO-mediated toxication of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analogues.
Journal: Chemical research in toxicology 19920101
Title: Effect of D1 and D2 agonists and antagonists on dyskinesia produced by L-dopa in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys.
Journal: The Journal of pharmacology and experimental therapeutics 19911001
Title: Unilateral MPTP-induced parkinsonism in monkeys. A quantitative autoradiographic study of dopamine D1 and D2 receptors and re-uptake sites.
Journal: Neuro-Chirurgie 19910101
Title: Oral levodopa dose-response study in MPTP-induced hemiparkinsonian monkeys: assessment with a new rating scale for monkey parkinsonism.
Journal: Movement disorders : official journal of the Movement Disorder Society 19910101
Title: Contrasting tissue factors predict heterogeneous striatal dopamine neurotoxicity after MPTP or methamphetamine treatment.
Journal: Brain research 19901126
Title: Nigrostriatal damage is required for induction of dyskinesias by L-DOPA in squirrel monkeys.
Journal: Clinical neuropharmacology 19901001
Title: (+)-PHNO: a new anti-parkinsonian agent which does not induce chorea in MPTP-treated squirrel monkeys.
Journal: Journal of neurology, neurosurgery, and psychiatry 19900701
Title: Differential effects of D1 and D2 agonists in MPTP-treated primates: functional implications for Parkinson's disease.
Journal: Neurology 19900601
Title: CCK-8S inhibits L-dopa-induced dyskinesias in parkinsonian squirrel monkeys.
Journal: Neurology 19900401
Title: Ro 19-6327, a reversible and highly selective monoamine, oxidase B inhibitor: a novel tool to explore the MAO-B function in humans.
Journal: Advances in neurology 19900101
Title: Induction of chorea and dystonia in parkinsonian primates.
Journal: Movement disorders : official journal of the Movement Disorder Society 19900101
Title: Neural mechanisms of dystonia: evidence from a 2-deoxyglucose uptake study in a primate model of dopamine agonist-induced dystonia.
Journal: Movement disorders : official journal of the Movement Disorder Society 19900101
Title: Characterisation of dyskinesias induced by L-dopa in MPTP-treated squirrel monkeys.
Journal: Psychopharmacology 19900101
Title: NB-355: a novel prodrug for L-DOPA with reduced risk for peak-dose dyskinesias in MPTP-treated squirrel monkeys.
Journal: Clinical neuropharmacology 19891001
Title: Levodopa-induced dyskinesias in parkinsonian monkeys: relationship to extent of nigrostriatal damage.
Journal: Pharmacology, biochemistry, and behavior 19890901
Title: The effect of deprenyl (selegiline) on the natural history of Parkinson's disease.
Journal: Science (New York, N.Y.) 19890804
Title: MPTP-induced parkinsonism in the monkey: neurochemical pathology, complications of treatment and pathophysiological mechanisms.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19870801
Title: Levodopa-induced dyskinesia and response fluctuations in primates rendered parkinsonian with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Journal: Journal of the neurological sciences 19870501
Title: Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): implications for treatment and the pathogenesis of Parkinson's disease.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19840201