Home Nitro Compounds 28448-04-6
28448-04-6,MFCD00233577
Catalog No.:AA007KIK

28448-04-6 | 2H-1-Benzopyran-2-one, 3-nitro-

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5mg
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1 week  
$131.00   $92.00
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100mg
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$169.00   $118.00
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250mg
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$285.00   $199.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA007KIK
Chemical Name:
2H-1-Benzopyran-2-one, 3-nitro-
CAS Number:
28448-04-6
Molecular Formula:
C9H5NO4
Molecular Weight:
191.1403
MDL Number:
MFCD00233577
SMILES:
[O-][N+](=O)c1cc2ccccc2oc1=O
Properties
Computed Properties
 
Complexity:
304  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
XLogP3:
1.9  

Downstream Synthesis Route

[1]Sharma,RajeshKumar;Priyanka;Katiyar,Diksha[MonatsheftefurChemie,2016,vol.147,#12,p.2157-2161]

[2]Vyasamudri,Sameer;Yang,Ding-Yah[Tetrahedron,2018,vol.74,#10,p.1092-1100]

[3]Butcher,R.J.;Katiyar,Diksha;Sharma,RajeshKumar;Singh,Vineeta;Tiwari,Neha[BioorganicChemistry,2020,vol.98]

[4]Manjappa,KiranB.;Lin,Jhih-Min;Yang,Ding-Yah[JournalofOrganicChemistry,2017,vol.82,#14,p.7648-7656]

[5]Thomas,Joice;John,Jubi;Parekh,Nikita;Dehaen,Wim[AngewandteChemie-InternationalEdition,2014,vol.53,#38,p.10155-10159][Angew.Chem.,2014,vol.53,#38,p.10319-10323,5]

[6]Locationinpatent:bodytextGavrilova;Semichenko;Korotchenko;Suboch[RussianJournalofOrganicChemistry,2008,vol.44,#4,p.624-625]

[7]Perrella;Chen;Behrens;KaltenbachIII;Seitz[JournalofMedicinalChemistry,1994,vol.37,#14,p.2232-2237]

[8]Locationinpatent:experimentalpartMatos,MariaJoao;Santana,Lourdes;Uriarte,Eugenio;Serra,Silvia;Corda,Marcella;Fadda,MariaBenedetta;Era,Benedetta;Fais,Antonella[JournalofPharmacyandPharmacology,2012,vol.64,#5,p.742-746]

[9]Matos,MariaJoao;Vazquez-Rodriguez,Saleta;Santana,Lourdes;Uriarte,Eugenio;Fuentes-Edfuf,Cristina;Santos,Ysabel;Munoz-Crego,Angeles[MedicinalChemistry,2012,vol.8,#6,p.1140-1145,6]

[1]Locationinpatent:experimentalpartMatos,MariaJoao;Santana,Lourdes;Uriarte,Eugenio;Serra,Silvia;Corda,Marcella;Fadda,MariaBenedetta;Era,Benedetta;Fais,Antonella[JournalofPharmacyandPharmacology,2012,vol.64,#5,p.742-746]

[2]Butcher,R.J.;Katiyar,Diksha;Sharma,RajeshKumar;Singh,Vineeta;Tiwari,Neha[BioorganicChemistry,2020,vol.98]

[1]Manjappa,KiranB.;Lin,Jhih-Min;Yang,Ding-Yah[JournalofOrganicChemistry,2017,vol.82,#14,p.7648-7656]

[2]CurrentPatentAssignee:TUNGHAIUNIVERSITY-US2018/273543,2018,A1Locationinpatent:Paragraph0093;0137-0138

152368-17-7    28448-04-6   
4-(3-hydroxy-6-(morpholinomethyl)-4-oxo-4H-pyran-2-yl)-2H-chromen-2-one 

[1]Komogortsev,AndreyN.;Lichitsky,BorisV.;Melekhina,ValeriyaG.;Minyaev,MikhailE.[TetrahedronLetters,2021,vol.68]

Literature

Title: Complete assignment of the 1H and 13C NMR spectra of antimicrobial 4-arylamino- 3-nitrocoumarin derivatives.

Journal: Magnetic resonance in chemistry : MRC 20101101

Title: Biorelevant refinement of the Caco-2 cell culture model to assess efficacy of paracellular permeability enhancers.

Journal: Journal of pharmaceutical sciences 20080501

Title: QSAR study of antimicrobial activity of some 3-nitrocoumarins and related compounds.

Journal: Journal of chemical information and modeling 20070101

Title: Diacylglycerol and its formation by phospholipase C regulate Rab- and SNARE-dependent yeast vacuole fusion.

Journal: The Journal of biological chemistry 20041217

Title: The beta-amyloid precursor protein controls a store-operated Ca2+ entry in cortical neurons.

Journal: The European journal of neuroscience 20041001

Title: 3-nitrocoumarins as dienophiles in the Diels-Alder reaction in water. An approach to the synthesis of nitrotetrahydrobenzo[c]chromenones and dihydrodibenzo[b,d]furans.

Journal: The Journal of organic chemistry 20031128

Title: Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins.

Journal: The Journal of biological chemistry 20020920

Title: Phospholipase C is required for glucose-induced calcium influx in budding yeast.

Journal: FEBS letters 20020605

Title: 3-Nitrocoumarin is an efficient inhibitor of budding yeast phospholipase-C.

Journal: Cell biochemistry and function 20011201

Title: PtdIns(4,5)P(2) and phospholipase C-independent Ins(1,4,5)P(3) signals induced by a nitrogen source in nitrogen-starved yeast cells.

Journal: The Biochemical journal 20011101

Title: Ward PD, et al. Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins. J Biol Chem. 2002 Sep 20;277(38):35760-5.

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Tags:28448-04-6 Molecular Formula|28448-04-6 MDL|28448-04-6 SMILES|28448-04-6 2H-1-Benzopyran-2-one, 3-nitro-