Name: Name:Thymidine, 2-thio-
Brand: AABLOCKS
SKU: AA002VO6
Rating: 90 (10 reviews)

Catalog No.: AA002VO6

28585-51-5 | Thymidine, 2-thio-

Pack Size： 10mg

Purity：

2 weeks

$206.00 $144.00

Pack Size： 25mg

Purity：

2 weeks

$295.00 $207.00

Pack Size： 50mg

Purity：

2 weeks

$474.00 $332.00

Pack Size： 100mg

Purity：

2 weeks

$697.00 $488.00

Pack Size： 250mg

Purity：

2 weeks

$1,411.00 $988.00

Quantity

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Technical Information

Catalog Number: AA002VO6

Chemical Name: Thymidine, 2-thio-

CAS Number: 28585-51-5

Molecular Formula: C10H14N2O4S

Molecular Weight: 258.2942

MDL Number: MFCD03788706

SMILES: OC[C@H]1O[C@H](C[C@@H]1O)n1cc(C)c(=O)[nH]c1=S

Properties

Complexity: 385

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 3

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 17

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: -0.6

Downstream Synthesis Route

40615-36-9

28585-51-5

125258-60-8

[1]Hassan,AbdallaE.A.;Sheng,Jia;Zhang,Wen;Huang,Zhen[JournaloftheAmericanChemicalSociety,2010,vol.132,p.2120-2121]

[2]Wang,Rui;Ranganathan,SrivathsanV.;Basanta-Sanchez,Maria;Shen,Fusheng;Chen,Alan;Sheng,Jia[ChemicalCommunications,2015,vol.51,#91,p.16369-16372]

[3]Haruehanroengra,Phensinee;Vangaveti,Sweta;Ranganathan,SrivathsanV.;Wang,Rui;Chen,Alan;Sheng,Jia[ACSChemicalBiology,2017,vol.12,#6,p.1504-1513]

[4]Yu,Ping;Zhou,Honglin;Li,Yuanyuan;Du,Zhifeng;Wang,Rui[Nucleosides,nucleotidesandnucleicacids,2021,vol.40,#7,p.754-766]

[5]Kuimelis;Nambiar[TetrahedronLetters,1993,vol.34,#24,p.3813-3816]

[6]Rajur;McLaughlin[TetrahedronLetters,1992,vol.33,#41,p.6081-6084]

4,4-dimethoxytritylchloride

28585-51-5

125258-60-8

[1]CurrentPatentAssignee:UNIVERSITYSYSTEMOFGEORGIA;SENARESEARCHINC-WO2010/135564,2010,A2Locationinpatent:Page/Pagecolumn52-53

125258-60-8

28585-51-5

[1]CurrentPatentAssignee:NIUAOWEITECHENGDUBIOTECHNOLOGY;XIRUIENTEBIOTECHCHENGDU-CN113004358,2021,ALocationinpatent:Paragraph0098;0100;0103-0104

Literature fold

Title: Self-Avoiding Molecular Recognition Systems (SAMRS).

Journal: Nucleic acids symposium series (2004)20080101

Title: Stability and mismatch discrimination of DNA duplexes containing 2,6-diaminopurine and 2-thiothymidine locked nucleic acid bases.

Journal: Nucleic acids symposium series (2004)20080101

Title: Triplex forming ability of oligonucleotides containing 2'-O-methyl-2-thiouridine or 2-thiothymidine.

Journal: Bioorganic & medicinal chemistry letters20060615

Title: Enhanced base pairing and replication efficiency of thiothymidines, expanded-size variants of thymidine.

Journal: Journal of the American Chemical Society20060118

Title: Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations.

Journal: Biochemistry20040120

Title: Synthesis and antiherpesvirus activities of 5-alkyl-2-thiopyrimidine nucleoside analogues.

Journal: Antiviral chemistry & chemotherapy20020301

Title: Anti-herpesvirus activities and cytotoxicities of 2-thiopyrimidine nucleoside analogues in vitro.

Journal: Antiviral chemistry & chemotherapy19990701

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