Title: Exploring a model of a chemokine receptor/ligand complex in an explicit membrane environment by molecular dynamics simulation: the human CCR1 receptor.
Journal: Journal of chemical information and modeling 20111024
Title: The chemokine, CCL3, and its receptor, CCR1, mediate thoracic radiation-induced pulmonary fibrosis.
Journal: American journal of respiratory cell and molecular biology 20110701
Title: Why CCR2 and CCR5 blockade failed and why CCR1 blockade might still be effective in the treatment of rheumatoid arthritis.
Journal: PloS one 20110101
Title: No significant effect of orally administered chemokine receptor 1 antagonist on intercellular adhesion molecule-3 expression in relapsing--remitting multiple sclerosis patients.
Journal: Multiple sclerosis (Houndmills, Basingstoke, England) 20100301
Title: Fibrogenesis in kidney transplantation: potential targets for prevention and therapy.
Journal: Transplantation 20091127
Title: Assessment of QT(c)-prolonging potential of BX471 in healthy volunteers. A 'thorough QT study' following ICH E14 using various QT(c) correction methods.
Journal: British journal of clinical pharmacology 20090901
Title: Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice.
Journal: The American journal of pathology 20070901
Title: Treatment with BX471, a CC chemokine receptor 1 antagonist, attenuates systemic inflammatory response during sepsis.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070401
Title: Beneficial effects of CCR1 blockade on the progression of chronic renal allograft damage.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301
Title: Treatment with BX471, a nonpeptide CCR1 antagonist, protects mice against acute pancreatitis-associated lung injury by modulating neutrophil recruitment.
Journal: Pancreas 20070301
Title: Blockade of chemokine signaling in patients with multiple sclerosis.
Journal: Neurology 20061128
Title: Predictions of CCR1 chemokine receptor structure and BX 471 antagonist binding followed by experimental validation.
Journal: The Journal of biological chemistry 20060915
Title: Effects of formulation and process variables on the release of a weakly basic drug from single unit extended release formulations.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060101
Title: Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model.
Journal: Clinical & experimental metastasis 20060101
Title: Development of a single unit extended release formulation for ZK 811 752, a weakly basic drug.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050901
Title: BX471: a CCR1 antagonist with anti-inflammatory activity in man.
Journal: Mini reviews in medicinal chemistry 20050901
Title: Development of a multi particulate extended release formulation for ZK 811 752, a weakly basic drug.
Journal: International journal of pharmaceutics 20050811
Title: Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice.
Journal: British journal of pharmacology 20050801
Title: Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease.
Journal: Journal of the American Society of Nephrology : JASN 20050401
Title: Chemokine receptor CCR1: a new target for progressive kidney disease.
Journal: American journal of nephrology 20050101
Title: CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome.
Journal: Kidney international 20041201
Title: Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice.
Journal: Journal of the American Society of Nephrology : JASN 20040601
Title: BX-471 Berlex.
Journal: Current opinion in investigational drugs (London, England : 2000) 20020601
Title: A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.
Journal: The Journal of clinical investigation 20020115
Title: CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model.
Journal: Immunology letters 20010402
Title: A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection.
Journal: The Journal of biological chemistry 20010209
Title: Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1.
Journal: The Journal of biological chemistry 20000623
Title: Liang M, et al. Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. J Biol Chem. 2000 Jun 23;275(25):19000-8.
Title: Anders HJ, et al. A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. J Clin Invest. 2002 Jan;109(2):251-9.
Title: Furuichi K, et al. Chemokine receptor CCR1 regulates inflammatory cell infiltration after renal ischemia-reperfusion injury. J Immunol. 2008 Dec 15;181(12):8670-6.
Title: Horuk R, et al. A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection. J Biol Chem. 2001 Feb 9;276(6):4199-204.
