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Home Oxazoles 288862-83-9
288862-83-9,MFCD28963803
Catalog No.:AA002WV7

288862-83-9 | 1-Hexanone, 1-oxazolo[4,5-b]pyridin-2-yl-6-phenyl-

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1mg
≥98%
in stock  
$392.00   $274.00
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5mg
≥98%
in stock  
$1,699.00   $1,189.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002WV7
Chemical Name:
1-Hexanone, 1-oxazolo[4,5-b]pyridin-2-yl-6-phenyl-
CAS Number:
288862-83-9
Molecular Formula:
C18H18N2O2
Molecular Weight:
294.3477
MDL Number:
MFCD28963803
SMILES:
O=C(c1nc2c(o1)cccn2)CCCCCc1ccccc1
Properties
Computed Properties
 
Complexity:
355  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
7  
XLogP3:
4.4  

Literature

Title: Design, synthesis and evaluation of polar head group containing 2-keto-oxazole inhibitors of FAAH.

Journal: Bioorganic & medicinal chemistry 20120115

Title: The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).

Journal: Bioorganic & medicinal chemistry letters 20110815

Title: 1-Indol-1-yl-propan-2-ones and related heterocyclic compounds as dual inhibitors of cytosolic phospholipase A(2)alpha and fatty acid amide hydrolase.

Journal: Bioorganic & medicinal chemistry 20100115

Title: Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors.

Journal: Journal of medicinal chemistry 20081211

Title: Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality.

Journal: Bioorganic & medicinal chemistry 20080215

Title: The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications.

Journal: Journal of medicinal chemistry 20050811

Title: Discovery of a potent, selective, and efficacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics.

Journal: Journal of medicinal chemistry 20050324

Title: Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity.

Journal: Bioorganic & medicinal chemistry letters 20050301

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SDS
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Tags:288862-83-9 Molecular Formula|288862-83-9 MDL|288862-83-9 SMILES|288862-83-9 1-Hexanone, 1-oxazolo[4,5-b]pyridin-2-yl-6-phenyl-