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29070-92-6,MFCD00238657
Catalog No.:AA002X5E

29070-92-6 | Lanost-8-en-21-oic acid, 3-(acetyloxy)-16-hydroxy-24-methylene-, (3β,16α)-

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1mg
98%(HPLC)powder
in stock  
$81.00   $57.00
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5mg
≥98%
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$173.00   $121.00
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10mg
≥98%
in stock  
$276.00   $193.00
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25mg
≥98%
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$605.00   $423.00
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1000mg
98% by HPLC
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$22,079.00   $15,455.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002X5E
Chemical Name:
Lanost-8-en-21-oic acid, 3-(acetyloxy)-16-hydroxy-24-methylene-, (3β,16α)-
CAS Number:
29070-92-6
Molecular Formula:
C33H52O5
Molecular Weight:
528.7630
MDL Number:
MFCD00238657
SMILES:
CC(=O)O[C@H]1CC[C@]2([C@H](C1(C)C)CCC1=C2CC[C@]2([C@@]1(C)C[C@H]([C@@H]2[C@H](C(=O)O)CCC(=C)C(C)C)O)C)C
Properties
Computed Properties
 
Complexity:
1020  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  
XLogP3:
7.2  

Literature

Title: Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

Journal: Chemico-biological interactions 20170801

Title: Pachymic acid stimulates glucose uptake through enhanced GLUT4 expression and translocation.

Journal: European journal of pharmacology 20101201

Title: [RP-HPLC simultaneous determination of five triterpenoid acids in different parts of Poria cocos by UV wavelengths switch].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100401

Title: Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cells.

Journal: Molecular carcinogenesis 20100301

Title: Effects of triterpenoids from Poria cocos Wolf on the serotonin type 3A receptor-mediated ion current in Xenopus oocytes.

Journal: European journal of pharmacology 20090801

Title: Absorption and transport of pachymic acid in the human intestinal cell line Caco-2 monolayers.

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080701

Title: Triterpene acids from Poria cocos and their anti-tumor-promoting effects.

Journal: Journal of natural products 20070601

Title: Induction of apoptosis in prostate cancer cells by pachymic acid from Poria cocos.

Journal: Biochemical and biophysical research communications 20050715

Title: Inhibitory effects of triterpenes isolated from Hoelen on free radical-induced lysis of red blood cells.

Journal: Phytotherapy research : PTR 20030201

Title: Chen Y, et al. Pachymic acid inhibits tumorigenesis in gallbladder carcinoma cells. Int J Clin Exp Med. 2015 Oct 15;8(10):17781-8.

Title: Ma J, et al. Pachymic acid induces apoptosis via activating ROS-dependent JNK and ER stress pathways in lung cancer cells. Cancer Cell Int. 2015 Aug 5;15:78.

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SDS
Tags:29070-92-6 Molecular Formula|29070-92-6 MDL|29070-92-6 SMILES|29070-92-6 Lanost-8-en-21-oic acid, 3-(acetyloxy)-16-hydroxy-24-methylene-, (3β,16α)-