Home Amines 29457-07-6
29457-07-6,MFCD07787410
Catalog No.:AA01CCK0

29457-07-6 | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-, disodiumsalt, (2S,5R,6R)-

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50mg
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$177.00   $124.00
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100mg
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250mg
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA01CCK0
Chemical Name:
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-, disodiumsalt, (2S,5R,6R)-
CAS Number:
29457-07-6
Molecular Formula:
C15H14N2Na2O6S2
Molecular Weight:
428.3910
MDL Number:
MFCD07787410
SMILES:
O=C(C(c1cscc1)C(=O)[O-])NC1C(=O)N2C1SC(C2C(=O)[O-])(C)C.[Na+].[Na+]
Properties
Computed Properties
 
Complexity:
629  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  

Literature

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Journal: Veterinary dermatology 20120401

Title: Nanoscale effects of antibiotics on P. aeruginosa.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20120101

Title: Population pharmacokinetic and pharmacodynamic modeling of high-dose intermittent ticarcillin-clavulanate administration in pediatric cystic fibrosis patients.

Journal: Clinical therapeutics 20111101

Title: Enhancement of antibiotic susceptibility of Stenotrophomonas maltophilia using a polyclonal antibody developed against an ABC multidrug efflux pump.

Journal: Canadian journal of microbiology 20111001

Title: In vitro elution of amikacin and ticarcillin from a resorbable, self-setting, fiber reinforced calcium phosphate cement.

Journal: Veterinary surgery : VS 20110701

Title: A prospective study of cefepime versus ticarcilline/clavulanate as empirical treatment of febrile neutropenia in lymphoma patients.

Journal: JPMA. The Journal of the Pakistan Medical Association 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Clinical profile of adult cystic fibrosis patients with frequent epidemic clones of Pseudomonas aeruginosa.

Journal: Respirology (Carlton, Vic.) 20100801

Title: High dose intermittent ticarcillin-clavulanate administration in pediatric cystic fibrosis patients.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20100701

Title: [Infectious keratitis and cosmetic lenses: a five-case retrospective study].

Journal: Journal francais d'ophtalmologie 20100401

Title: Antimicrobial delivery by intrasynovial catheterisation with systemic administration for equine synovial trauma and sepsis.

Journal: Australian veterinary journal 20100401

Title: Agrobacterium-mediated transformation of Fraxinus pennsylvanica hypocotyls and plant regeneration.

Journal: Plant cell reports 20090601

Title: The costs of treatment of early and chronic Pseudomonas aeruginosa infection in cystic fibrosis patients.

Journal: Journal of chemotherapy (Florence, Italy) 20090401

Title: A bullous lesion in a neutropenic adolescent.

Journal: Pediatric emergency care 20090201

Title: [Aerobic bacteria associated with acute appendicitis in children].

Journal: Annales francaises d'anesthesie et de reanimation 20090101

Title: Development of a new HPLC method for the simultaneous determination of ticarcillin and clavulanic acid in pharmaceutical formulations.

Journal: Journal of AOAC International 20090101

Title: Comparison of ticarcillin and piperacillin in Kenney's semen extender.

Journal: Theriogenology 20071001

Title: Ertapenem or ticarcillin/clavulanate for the treatment of intra-abdominal infections or acute pelvic infections in pediatric patients.

Journal: American journal of surgery 20070901

Title: Alcaligenes xylosoxidans conjunctivitis.

Journal: Cornea 20070801

Title: Sensitivity pattern of gram negative bacilli to three beta-lactam/beta-lactamase inhibitor combinations using the automated API system.

Journal: Indian journal of medical microbiology 20070701

Title: Outpatient intravenous antibiotics for methicillin-resistant Staphylococcus aureus sinusitis.

Journal: American journal of rhinology 20070101

Title: [Characteristic of clinical strains of gram-negative obligate anaerobes].

Journal: Medycyna doswiadczalna i mikrobiologia 20070101

Title: In vitro pyrogenicity of Gram-positive bacteria--validation of the kit using fresh human whole blood.

Journal: Pharmeuropa scientific notes 20060801

Title: [Prospects of using timentin (ticarcillin/clavulanate) for the treatment of the surgical infections].

Journal: Klinichna khirurhiia 20060601

Title: Agrobacterium-mediated genetic transformation of the desiccation tolerant resurrection plant Ramonda myconi (L.) Rchb.

Journal: Plant cell reports 20060501

Title: Comparative in vitro activity of beta-lactam/beta-lactamase inhibitor combinations against gram negative bacteria.

Journal: The Indian journal of medical research 20051101

Title: Continuous infusion of ticarcillin-clavulanate for home treatment of serious infections: clinical efficacy, safety, pharmacokinetics and pharmacodynamics.

Journal: International journal of antimicrobial agents 20050601

Title: Acinetobacter baumanii folliculitis in a patient with AIDS.

Journal: Clinical and experimental dermatology 20050501

Title: Pharmacokinetics of ticarcillin in the loggerhead sea turtle (Caretta caretta) after single intravenous and intramuscular injections.

Journal: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20050301

Title: Effect of bovine lactoferrin on the MICs of ampicillin/sulbactam (UNASYN), amoxicillin/clavulanic acid (Augmentin), ticarcillin clavulanate (Timentin), and piperacillin-tazobactam (ZOSYN), against clinical and environmental isolates of motile Aeromonas.

Journal: The Journal of the American Osteopathic Association 20050101

Title: Comparison of antimicrobial resistance of Acinetobacter baumannii clinical isolates from Shanghai and Hong Kong.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101

Title: [Bacterial meningitis and Pseudomonas aeruginosa: apropos of a case].

Journal: Revista cubana de medicina tropical 20050101

Title: Impact of a formulary switch from ticarcillin-clavulanate to piperacillin-tazobactam on colonization with vancomycin-resistant enterococci.

Journal: American journal of infection control 20041201

Title: [Pseudomonas aeruginosa: a multicentric study of antibiotic resistance (1999-2000)].

Journal: La Tunisie medicale 20041201

Title: Clinical efficacy, tolerability, and cost savings associated with the use of open-label metronidazole plus ceftriaxone once daily compared with ticarcillin/clavulanate every 6 hours as empiric treatment for diabetic lower-extremity infections in older males.

Journal: The American journal of geriatric pharmacotherapy 20040901

Title: The value of a CT-guided fine needle aspirate in infants with lung abscess.

Journal: Journal of paediatrics and child health 20040801

Title: [Surveillance on antibiotic resistance of Stenotrophomonas maltophilia in Chengdu and Chongqing area].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20040101

Title: [Management of ENT diseases complications using ticarcillin clavulanate].

Journal: Vestnik otorinolaringologii 20040101

Title: Detection of ticarcillin-clavulonic acid susceptibility with microdilution method in Citrobacter, Hafnia, Proteus and some gram negative bacteria.

Journal: Drug metabolism and drug interactions 20040101

Title: [Antibiotic susceptibility and occurrence of ESBL in Pseudomonas aeruginosa strains isolated from different clinical specimens].

Journal: Medycyna doswiadczalna i mikrobiologia 20040101

Title: Haemorrhagic cystitis with ticarcillin: risk factors include cystic fibrosis.

Journal: Prescrire international 20031001

Title: Simultaneous determination of ticarcillin and clavulanate in rabbit serum and tissue cage fluid by liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030905

Title: Early antibiotic selection and efficient rooting and acclimatization improve the production of transgenic plum plants (Prunus domestica L.).

Journal: Plant cell reports 20030801

Title: [Community-acquired Pseudomonas aeruginosa bacteremic pneumonia in a 'healthy' subject].

Journal: Presse medicale (Paris, France : 1983) 20030712

Title: Cefepime versus ticarcillin and clavulanate potassium and aztreonam for febrile neutropenia therapy in high-dose chemotherapy patients.

Journal: American journal of clinical oncology 20030601

Title: Ticarcillin-clavulanic acid plus amikacin versus ceftazidime plus amikacin in the empirical treatment of fever in acute leukemia: a prospective randomized trial.

Journal: Journal of chemotherapy (Florence, Italy) 20030601

Title: Application of MEKC for determination of ticarcillin and clavulanic acid in Timentin intravenous preparation.

Journal: Journal of pharmaceutical and biomedical analysis 20030424

Title: Evaluation of ticarcillin/clavulanic acid versus ceftriaxone plus amikacin for fever and neutropenia in pediatric patients with leukemia and lymphoma.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20030401

Title: Agrobacterium radiobacter bacteremia in pediatric patients: case report and review.

Journal: The Pediatric infectious disease journal 20030201

Title: Late bacterial keratitis after implantation of intrastromal corneal ring segments.

Journal: Journal of cataract and refractive surgery 20030201

Title: Efficiency of procedures for induction and cultivation of Pseudomonas syringae pv. pisi L-form.

Journal: Microbiological research 20030101

Title: Antibiotic-associated maculopapular reaction.

Journal: The Annals of pharmacotherapy 20021201

Title: Once-daily, high-dose levofloxacin versus ticarcillin-clavulanate alone or followed by amoxicillin-clavulanate for complicated skin and skin-structure infections: a randomized, open-label trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020815

Title: [Hepatic inflammatory pseudotumor regressing with antibiotic therapy].

Journal: Presse medicale (Paris, France : 1983) 20020525

Title: Growth of cell-wall-deficient variants of Enterobacter cloacae facilitates beta-lactamase derepressed mutants.

Journal: International journal of antimicrobial agents 20020501

Title: Timentin overdose. 'No admittance' to the pharmacy?

Journal: Nursing 20020401

Title: Antibiotic-induced recurring interstitial nephritis.

Journal: Pediatric nephrology (Berlin, Germany) 20020101

Title: Severe cellulitis/myositis caused by Stenotrophomonas maltophilia.

Journal: The Annals of pharmacotherapy 20020101

Title: Clinical evaluation of the Vitek automated system with cards GNS 122 and 127 and VTK-R07.01 software for antimicrobial susceptibility testing of Pseudomonas aeruginosa.

Journal: Diagnostic microbiology and infectious disease 20020101

Title: Stability of piperacillin and ticarcillin in AutoDose infusion system bags.

Journal: The Annals of pharmacotherapy 20011101

Title: Bacteroides fragilis arthritis in a patient with sickle cell disease.

Journal: The American journal of medicine 20010801

Title: Pneumonia after cardiac surgery is predictable by tracheal aspirates but cannot be prevented by prolonged antibiotic prophylaxis.

Journal: The Annals of thoracic surgery 20010701

Title: Acute epiglottitis: a review of 80 patients.

Journal: The Journal of laryngology and otology 20010101

Title: In vitro susceptibility of Stenotrophomonas maltophilia to various antimicrobial combinations.

Journal: Diagnostic microbiology and infectious disease 20010101

Title: [Antibiotic prophylaxis of postoperative complications in surgical treatment of pulmonary, tracheal and mediastinal tumors].

Journal: Anesteziologiia i reanimatologiia 20010101

Title: Positive direct antiglobulin tests and haemolytic anaemia following therapy with beta-lactamase inhibitor containing drugs may be associated with nonimmunologic adsorption of protein onto red blood cells.

Journal: British journal of haematology 19980301

Title: Intrahepatic cholestasis due to ticarcillin-clavulanate.

Journal: The American journal of gastroenterology 19950401

Title: Hypokalemia associated with ticarcillin-clavulanic acid.

Journal: Maryland medical journal (Baltimore, Md. : 1985) 19931001

Title: Sensitization to aztreonam and cross-reactivity with other beta-lactam antibiotics in high-risk patients with cystic fibrosis.

Journal: The Journal of allergy and clinical immunology 19910101

Title: Sodium protects against nephrotoxicity in patients receiving amphotericin B.

Journal: The American journal of the medical sciences 19891101

Title: In-vitro susceptibility of Mycobacterium tuberculosis, Mycobacterium bovis and Mycobacterium kansasii to amoxycillin and ticarcillin in combination with clavulanic acid.

Journal: The Journal of antimicrobial chemotherapy 19881201

Title: Nephrotoxicity in leukemic patients receiving empirical amphotericin B and aminoglycosides.

Journal: Southern medical journal 19880901

Title: In vitro activity of antimicrobial agents against mycobacteria.

Journal: Drugs under experimental and clinical research 19880101

Title: Action of antituberculous and beta-lactam drugs (including imipenem) against extra- and intra-cellularly growing Mycobacterium avium-intracellulare.

Journal: Annales de l'Institut Pasteur. Microbiology 19880101

Title: Broth microdilution testing of susceptibilities to 30 antimicrobial agents of Mycobacterium avium strains from patients with acquired immune deficiency syndrome.

Journal: Antimicrobial agents and chemotherapy 19871001

Title: Tobramycin and ticarcillin as empiric therapy for febrile patients with granulocytopenia: a reevaluation.

Journal: Southern medical journal 19870701

Title: Amphotericin-B nephrotoxicity in humans decreased by sodium supplements with coadministration of ticarcillin or intravenous saline.

Journal: Klinische Wochenschrift 19870601

Title: In vitro susceptibility of Mycobacterium tuberculosis, Mycobacterium africanum, Mycobacterium bovis, Mycobacterium avium, Mycobacterium fortuitum, and Mycobacterium chelonae to ticarcillin in combination with clavulanic acid.

Journal: Antimicrobial agents and chemotherapy 19870101

Title: Drug-induced hemorrhagic cystitis.

Journal: Clinical pharmacy 19860701

Title: An evaluation of the safety and tolerance of Timentin.

Journal: The Journal of antimicrobial chemotherapy 19860501

Title: Attenuation of experimental tobramycin nephrotoxicity by ticarcillin.

Journal: Antimicrobial agents and chemotherapy 19850601

Title: Ticarcillin-induced cystitis. Cross-reactivity with related penicillins.

Journal: American journal of diseases of children (1960) 19840701

Title: Ticarcillin-induced immune haemolytic anaemia.

Journal: Scandinavian journal of haematology 19820501

Title: Ticarcillin associated hypokalemia.

Journal: Clinical biochemistry 19820401

Title: Antibiotic combination-associated nephrotoxicity in granulocytopenic patients with cancer.

Journal: Archives of internal medicine 19811201

Title: Use of probenecid in ticarcillin-induced hypokalemia.

Journal: Clinical therapeutics 19800101

Title: Comparative auditory toxicity of aminoglycoside antibiotics in leukopenic patients.

Journal: American journal of hospital pharmacy 19790801

Title: Neurotoxicity due to ticarcillin in patient with renal failure.

Journal: Lancet (London, England) 19790317

Title: [Comparative study of ticarcillin and of carbenicillin as prophylactic treatment in the oncologic surgery of head and neck (author's transl)].

Journal: Acta chirurgica Belgica 19760101

Title: Spierer O, et al. Comparative activity of antimicrobials against Pseudomonas aeruginosa, Achromobacter xylosoxidans and Stenotrophomonas maltophilia keratitis isolates. Br J Ophthalmol. 2018 May;102(5):708-712.

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Tags:29457-07-6 Molecular Formula|29457-07-6 MDL|29457-07-6 SMILES|29457-07-6 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-carboxy-3-thienylacetyl]amino]-3,3-dimethyl-7-oxo-, disodiumsalt, (2S,5R,6R)-