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30286-75-0,MFCD05664584
Catalog No.:AA01CBV0

30286-75-0 | 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-ethyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide,(1a,2b,4b,5a,7b)-

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5mg
>98.00%
3 weeks  
$779.00   $545.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA01CBV0
Chemical Name:
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-ethyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide,(1a,2b,4b,5a,7b)-
CAS Number:
30286-75-0
Molecular Formula:
C19H26BrNO4
Molecular Weight:
412.3180
MDL Number:
MFCD05664584
SMILES:
OC[C@H](c1ccccc1)C(=O)O[C@@H]1C[C@@H]2[C@@H]3[C@H]([C@H](C1)[N@+]2(C)CC)O3.[Br-]
Properties
Computed Properties
 
Complexity:
472  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  

Literature

Title: Anticholinergic therapy for acute asthma in children.

Journal: The Cochrane database of systematic reviews 20120418

Title: Effects of tiotropium on sympathetic activation during exercise in stable chronic obstructive pulmonary disease patients.

Journal: International journal of chronic obstructive pulmonary disease 20120101

Title: Beta2-adrenergic receptor polymorphisms as a determinant of preferential bronchodilator responses to β2-agonist and anticholinergic agents in Japanese patients with chronic obstructive pulmonary disease.

Journal: Pharmacogenetics and genomics 20111101

Title: Effects of inhalation or incubation of oxitropium bromide on diaphragm muscle contractility in mice.

Journal: Allergology international : official journal of the Japanese Society of Allergology 20110901

Title: The thermosalient phenomenon. 'Jumping crystals' and crystal chemistry of the anticholinergic agent oxitropium bromide.

Journal: Journal of the American Chemical Society 20101013

Title: Comparison of the protective effect amongst anticholinergic drugs on methacholine-induced bronchoconstriction in asthma.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma 20080601

Title: High-resolution computed tomography evaluation of airway distensibility in asthmatic and healthy subjects.

Journal: La Radiologia medica 20080201

Title: Inhaled corticosteroids as additional treatment in alpha-1-antitrypsin-deficiency-related COPD.

Journal: Respiration; international review of thoracic diseases 20080101

Title: Long-term effect of the beta2-receptor agonist procaterol on daily life performance and exercise capacity in patients with stable chronic obstructive pulmonary disease. Clinical study with special reference to health-related quality of life and activities of daily living.

Journal: Arzneimittel-Forschung 20080101

Title: Effect of resection of the posterior nasal nerve on functional and morphological changes in the inferior turbinate mucosa.

Journal: Acta oto-laryngologica 20080101

Title: Effects of replacing oxitropium with tiotropium on pulmonary function in patients with COPD: a randomized study.

Journal: Respiratory medicine 20070301

Title: The development of anticholinergics in the management of COPD.

Journal: International journal of chronic obstructive pulmonary disease 20070301

Title: Use of tiotropium bromide for pre-operative treatment in chronic obstructive pulmonary disease patients: comparison with oxitropium bromide.

Journal: Internal medicine (Tokyo, Japan) 20070101

Title: Anticholinergic agents in asthma and COPD.

Journal: European journal of pharmacology 20060308

Title: Increased responses to inhaled oxitropium bromide in asthmatic patients with active hepatitis C virus infection.

Journal: Chest 20040401

Title: [Beta 2-adrenoceptor polymorphism and effects of inhaled beta 2-stimulant (procaterol) and an anti-cholinergic drug (oxitropium) on the airway resistance].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20040301

Title: Reproducibility of forced inspiratory and expiratory volumes after bronchodilation in patients with COPD or asthma.

Journal: Respiratory medicine 20030501

Title: Efficacy of a consensus protocol therapy in adults with acute, severe asthma.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030301

Title: Effect of inhaled bronchodilators on inspiratory capacity and dyspnoea at rest in COPD.

Journal: The European respiratory journal 20030101

Title: Efficacy and safety of oxitropium bromide, theophylline and their combination in COPD patients: a double-blind, randomized, multicentre study (BREATH Trial).

Journal: Respiratory medicine 20021101

Title: Bronchodilating effect of oxitropium bromide in heart disease patients with exacerbations of COPD: double-blind, randomized, controlled study.

Journal: Respiratory medicine 20020301

Title: Efficacy of inhaled anticholinergics and anesthesia in treatment of a patient in status asthmaticus.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma 20020201

Title: Anticholinergics in the treatment of chronic obstructive pulmonary disease.

Journal: Respiration; international review of thoracic diseases 20020101

Title: Anti-cholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease.

Journal: The Cochrane database of systematic reviews 20020101

Title: Comparison of the effect of oxitropium bromide and of slow-release theophylline on nocturnal asthma.

Journal: Postgraduate medical journal 19880801

Title: Shindoh C, et al. Effects of inhalation or incubation of oxitropium bromide on diaphragm muscle contractility in mice. Allergol Int. 2011 Sep;60(3):365-72.

Title: Kohno SW, et al. Effect of oxitropium bromide (Ba253) on increased airway resistance induced by various agonists and antigen in the guinea pig. Jpn J Pharmacol. 1989 Aug;50(4):455-66.

Title: Takeyama K, et al. Effect of oxitropium bromide on histamine-induced airway goblet cell secretion. Am J Respir Crit Care Med. 1996 Jul;154(1):231-6.

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Tags:30286-75-0 Molecular Formula|30286-75-0 MDL|30286-75-0 SMILES|30286-75-0 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-ethyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide,(1a,2b,4b,5a,7b)-