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303997-35-5,MFCD00140737
Catalog No.:AA01DU7U

303997-35-5 | R-7050

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$18.00   $13.00
- +
5mg
97%
in stock  
$44.00   $31.00
- +
10mg
97%
in stock  
$63.00   $44.00
- +
25mg
97%
in stock  
$91.00   $64.00
- +
50mg
97%
in stock  
$131.00   $92.00
- +
100mg
97%
in stock  
$214.00   $150.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DU7U
Chemical Name:
R-7050
CAS Number:
303997-35-5
Molecular Formula:
C16H8ClF3N4S
Molecular Weight:
380.7747
MDL Number:
MFCD00140737
SMILES:
Clc1ccc2c(c1)n1c(c(n2)Sc2ccccc2)nnc1C(F)(F)F
Properties
Computed Properties
 
Complexity:
477  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
2  
XLogP3:
5.5  

Literature

Title: Role of tumor necrosis factor-α and interleukin-1β in anorexia induction following oral exposure to the trichothecene deoxynivalenol (vomitoxin) in the mouse.

Journal: The Journal of toxicological sciences 20140101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Gururaja TL, et al. A class of small molecules that inhibit TNFalpha-induced survival and death pathways viaprevention of interactions between TNFalphaRI, TRADD, and RIP1. Chem Biol. 2007 Oct;14(10):1105-18.

Title: King MD, et al. TNF-alpha receptor antagonist, R-7050, improves neurological outcomes following intracerebralhemorrhage in mice. Neurosci Lett. 2013 May 10;542:92-6.

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SDS
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