Home Amines 30486-73-8
30486-73-8,MFCD06659790
Catalog No.:AA00308B

30486-73-8 | 5-Fluoro-1h-benzimidazole-2-amine

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250mg
95%
in stock  
$61.00   $43.00
- +
1g
95%
in stock  
$152.00   $107.00
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5g
95%
in stock  
$428.00   $300.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00308B
Chemical Name:
5-Fluoro-1h-benzimidazole-2-amine
CAS Number:
30486-73-8
Molecular Formula:
C7H6FN3
Molecular Weight:
151.1410
MDL Number:
MFCD06659790
SMILES:
Fc1ccc2c(c1)[nH]c(n2)N
Properties
Computed Properties
 
Complexity:
153  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
XLogP3:
1.4  

Downstream Synthesis Route

[1]Frei,Reto;Breitbach,AnthonyS.;Blackwell,HelenE.[AngewandteChemie-InternationalEdition,2012,vol.51,#21,p.5226-5229]

[2]Namani,Vasu;BharathKumarGoud;BharathiKumari;Kumbham,Ramesh;Balakrishna,Kannoju;Bhima,Bhukya[AsianJournalofChemistry,2015,vol.27,#12,p.4575-4578]

[3]Ueda,Satoshi;Buchwald,StephenL.[AngewandteChemie-InternationalEdition,2012,vol.51,#41,p.10364-10367]

[4]CurrentPatentAssignee:EXELIXISINC-WO2008/42282,2008,A2Locationinpatent:Page/Pagecolumn213-214

[5]Powers,JayP.;Li,Shyun;Jaen,JuanC.;Liu,Jinqian;Walker,NigelP.C.;Wang,Zhulun;Wesche,Holger[BioorganicandMedicinalChemistryLetters,2006,vol.16,#11,p.2842-2845]

[6]Kong,Weiguang;Zhou,Yao;Song,Qiuling[AdvancedSynthesisandCatalysis,2018,vol.360,#10,p.1943-1948]

[7]CurrentPatentAssignee:OREGONSTATEBOARDOFHIGHEREDUCATION-WO2021/22061,2021,A1Locationinpatent:Page/Pagecolumn44;48

[8]Ferreira,RafaelAugustoAlves;Junior,CelsodeOliveiraRezende;Martinez,PabloDavidGrigol;Koovits,PaulJohn;Soares,BrunaMiranda;Ferreira,LeonardoL.G.;Michelan-Duarte,Simone;Chelucci,RafaelConsolin;Andricopulo,AdrianoD.;Galuppo,MarianaK.;Uliana,SilviaR.B.;Matheeussen,An;Caljon,Guy;Maes,Louis;Campbell,Simon;Kratz,JadelM.;Mowbray,CharlesE.;Dias,LuizCarlos[PLoSNeglectedTropicalDiseases,2021,vol.15,#2]

30486-73-8    121-92-6   
<i>N</i>-(5-fluoro-1<i>H</i>-benzoimidazol-2-yl)-3-nitro-benzamide 

[1]Powers,JayP.;Li,Shyun;Jaen,JuanC.;Liu,Jinqian;Walker,NigelP.C.;Wang,Zhulun;Wesche,Holger[BioorganicandMedicinalChemistryLetters,2006,vol.16,#11,p.2842-2845]

30486-73-8   
5-fluoro-2-aminobenzimidazolehydrochloride 

[1]Frei,Reto;Breitbach,AnthonyS.;Blackwell,HelenE.[AngewandteChemie-InternationalEdition,2012,vol.51,#21,p.5226-5229]

[1]Ueda,Satoshi;Buchwald,StephenL.[AngewandteChemie-InternationalEdition,2012,vol.51,#41,p.10364-10367]

Literature

Title: Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.

Journal: The Biochemical journal 20101001

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SDS
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