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3067-14-9,MFCD00871838
Catalog No.:AA0030PM

3067-14-9 | Benzo[a]pyrene-3,6-dione

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1mg
3 weeks  
$326.00   $228.00
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10mg
3 weeks  
$1,376.00   $963.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0030PM
Chemical Name:
Benzo[a]pyrene-3,6-dione
CAS Number:
3067-14-9
Molecular Formula:
C20H10O2
Molecular Weight:
282.2922
MDL Number:
MFCD00871838
SMILES:
O=C1C=Cc2c3c1ccc1c3c(cc2)c2c(C1=O)cccc2
Properties
Computed Properties
 
Complexity:
548  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
4.3  

Literature

Title: Acute changes in pulse pressure in relation to constituents of particulate air pollution in elderly persons.

Journal: Environmental research 20120801

Title: Selective accurate-mass-based analysis of 11 oxy-PAHs on atmospheric particulate matter by pressurized liquid extraction followed by high-performance liquid chromatography and magnetic sector mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20120201

Title: Potent phototoxicity of marine bunker oil to translucent herring embryos after prolonged weathering.

Journal: PloS one 20120101

Title: Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.

Journal: Chemical research in toxicology 20111219

Title: Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli.

Journal: Molecular pharmacology 20091101

Title: EGF-receptor phosphorylation and downstream signaling are activated by benzo[a]pyrene 3,6-quinone and benzo[a]pyrene 1,6-quinone in human mammary epithelial cells.

Journal: Toxicology and applied pharmacology 20090315

Title: Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in breast epithelial cell lines.

Journal: The Journal of toxicological sciences 20090201

Title: Method development and validation for optimized separation of benzo[a]pyrene-quinone isomers using liquid chromatography-mass spectrometry and chemometric response surface methodology.

Journal: Journal of chromatography. A 20071012

Title: Benzo[a]pyrene-3,6-dione inhibited VEGF expression through inducing HIF-1alpha degradation.

Journal: Biochemical and biophysical research communications 20070601

Title: Activation of dioxin response element (DRE)-associated genes by benzo(a)pyrene 3,6-quinone and benzo(a)pyrene 1,6-quinone in MCF-10A human mammary epithelial cells.

Journal: Toxicology and applied pharmacology 20070601

Title: Determination of oxygenated polycyclic aromatic hydrocarbons in particulate matter using high-performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20061110

Title: Effects of riboflavin on the phototransformation of benzo[a]pyrene.

Journal: Chemosphere 20060501

Title: Benzo(a)pyrene quinones increase cell proliferation, generate reactive oxygen species, and transactivate the epidermal growth factor receptor in breast epithelial cells.

Journal: Cancer research 20031115

Title: Role of cytochrome P4501B1 in benzo[a]pyrene bioactivation to DNA-binding metabolites in mouse vascular smooth muscle cells: evidence from 32P-postlabeling for formation of 3-hydroxybenzo[a]pyrene and benzo[a]pyrene-3,6-quinone as major proximate genotoxic intermediates.

Journal: The Journal of pharmacology and experimental therapeutics 20030401

Title: Identification of albumin precursor protein, Phi AP3, and alpha-smooth muscle actin as novel components of redox sensing machinery in vascular smooth muscle cells.

Journal: Molecular pharmacology 20020501

Title: Intestinal bioavailability and biotransformation of 3-hydroxybenzo(a)pyrene in an isolated perfused preparation from channel catfish, Ictalurus punctatus.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010501

Title: Profiles of antioxidant/electrophile response element (ARE/EpRE) nuclear protein binding and c-Ha-ras transactivation in vascular smooth muscle cells treated with oxidative metabolites of benzo[a]pyrene.

Journal: Biochemical pharmacology 20001101

Title: Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidant-responsive element.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20000915

Title: Hydroquinones cause specific mutations and lead to cellular transformation and in vivo tumorigenesis.

Journal: British journal of cancer 19980801

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