Home Amines 3084-04-6
3084-04-6,MFCD00747789
Catalog No.:AA00BLJI

3084-04-6 | 4-Benzofuran-2-yl-thiazol-2-ylamine

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100mg
97%
1 week  
$97.00   $68.00
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250mg
97%
1 week  
$148.00   $104.00
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1g
97%
1 week  
$450.00   $315.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00BLJI
Chemical Name:
4-Benzofuran-2-yl-thiazol-2-ylamine
CAS Number:
3084-04-6
Molecular Formula:
C11H8N2OS
Molecular Weight:
216.2590
MDL Number:
MFCD00747789
SMILES:
Nc1scc(n1)c1cc2c(o1)cccc2
Properties
Computed Properties
 
Complexity:
239  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2.7  

Downstream Synthesis Route

[1]Othman,DinaI.;Abdelal,AliM.M.;El-Sayed,MagdaA.;ElBialy,SerryA.A.[HeterocyclicCommunications,2013,vol.19,#1,p.29-35]

[2]Annadurai,Sivakumar;Martinez,Rogelio;Canney,DanielJ.;Eidem,Tess;Dunman,PaulM.;Abou-Gharbia,Magid[BioorganicandMedicinalChemistryLetters,2012,vol.22,#24,p.7719-7725]

[3]Kurt,BelmaZengin;Gazioglu,Isil;Basile,Livia;Sonmez,Fatih;Ginex,Tiziana;Kucukislamoglu,Mustafa;Guccione,Salvatore[EuropeanJournalofMedicinalChemistry,2015,vol.102,p.80-92]

[4]Locationinpatent:schemeortableVenkatesh,BhoviK.;Bodke,YadavD.;Biradar[Phosphorus,SulfurandSiliconandtheRelatedElements,2010,vol.185,#9,p.1926-1931]

404-71-7    3084-04-6   
1-(4-(benzofuran-2-yl)thiazol-2-yl)-3-(3-fluorophenyl)urea 

[1]Kurt,BelmaZengin;Gazioglu,Isil;Basile,Livia;Sonmez,Fatih;Ginex,Tiziana;Kucukislamoglu,Mustafa;Guccione,Salvatore[EuropeanJournalofMedicinalChemistry,2015,vol.102,p.80-92]

Literature

Title: Preparation of leukotriene B(4) inhibitory active 2- and 3-(2-aminothiazol-4-yl)benzo[b]furan derivatives and their growth inhibitory activity on human pancreatic cancer cells.

Journal: Organic & biomolecular chemistry 20080807

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

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SDS
Tags:3084-04-6 Molecular Formula|3084-04-6 MDL|3084-04-6 SMILES|3084-04-6 4-Benzofuran-2-yl-thiazol-2-ylamine