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31252-42-3,MFCD00006006
Catalog No.:AA003KR8

31252-42-3 | 4-Benzylpiperidine

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Purity
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Price(USD)
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1g
95%
in stock  
$18.00   $13.00
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5g
95%
in stock  
$24.00   $17.00
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25g
95%
in stock  
$59.00   $42.00
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100g
≥ 99% (GC)
in stock  
$165.00   $115.00
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250g
≥ 99% (GC)
in stock  
$329.00   $230.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003KR8
Chemical Name:
4-Benzylpiperidine
CAS Number:
31252-42-3
Molecular Formula:
C12H17N
Molecular Weight:
175.2701
MDL Number:
MFCD00006006
SMILES:
N1CCC(CC1)Cc1ccccc1
NSC Number:
30346
Properties
Properties
 
BP:
279.6°C at 760 mmHg  
Form:
Liquid  
MP:
6-7 °C(lit.)  
Refractive Index:
n20/D 1.537(lit.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
132  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.5  

Literature

Title: Structural, vibrational and DSC investigations of the bis-4-benzyl piperidinium tetraoxoselenate monohydrate crystal.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

Title: Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120601

Title: Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.

Journal: The Journal of pharmacology and experimental therapeutics 20090401

Title: Synthesis and pharmacological properties of new derivatives of 4-alkoxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones.

Journal: Acta poloniae pharmaceutica 20090101

Title: Novel sigma receptor ligands: synthesis and biological profile.

Journal: Journal of medicinal chemistry 20070308

Title: JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast.

Journal: Molecular pharmacology 20061001

Title: Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.

Journal: Journal of medicinal chemistry 20060504

Title: A novel class of sodium/calcium exchanger inhibitor: design, synthesis, and structure-activity relationships of 3,4-dihydro-2(1H)-quinazolinone derivatives.

Journal: Bioorganic & medicinal chemistry 20050601

Title: Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency.

Journal: Journal of medicinal chemistry 20050324

Title: Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.

Journal: Journal of medicinal chemistry 20050113

Title: CCR5 antagonists as anti-HIV-1 agents. Part 2: Synthesis and biological evaluation of N-[3-(4-benzylpiperidin-1-yl)propyl]-N,N'-diphenylureas.

Journal: Bioorganic & medicinal chemistry 20040501

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