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312917-14-9,MFCD01005305
Catalog No.:AA00C0UL

312917-14-9 | Tcs jnk 5a

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
98%
in stock  
$75.00   $53.00
- +
100mg
≥99%(HPLC)
in stock  
$711.00   $498.00
- +
250mg
≥99%(HPLC)
in stock  
$1,529.00   $1,070.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C0UL
Chemical Name:
Tcs jnk 5a
CAS Number:
312917-14-9
Molecular Formula:
C20H16N2OS
Molecular Weight:
332.4188
MDL Number:
MFCD01005305
SMILES:
N#Cc1c(sc2c1CCCC2)NC(=O)c1cccc2c1cccc2
Properties
Properties
 
BP:
486.8°C at 760 mmHg  
Form:
Solid  
MP:
88-90ºC  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
527  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
5.5  

Literature

Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.

Journal: Bioorganic & medicinal chemistry letters 20130801

Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

Journal: The Biochemical journal 20130415

Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Journal: Nature biotechnology 20111101

Title: N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3.

Journal: Bioorganic & medicinal chemistry letters 20070301

Title: SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20011120

Title: Angell RM, et al. N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1296-301.

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