Home Sulfonamines 3144-09-0
3144-09-0,MFCD00007940
Catalog No.:AA003522

3144-09-0 | Methanesulfonamide

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5g
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25g
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100g
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500g
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003522
Chemical Name:
Methanesulfonamide
CAS Number:
3144-09-0
Molecular Formula:
CH5NO2S
Molecular Weight:
95.1209
MDL Number:
MFCD00007940
SMILES:
CS(=O)(=O)N
NSC Number:
271
Properties
Properties
 
BP:
208.2°C at 760 mmHg  
Form:
Solid  
MP:
85-89 °C(lit.)  
Refractive Index:
1.5130 (estimate)  
Solubility:
Slightly soluble in DMSO and methanol.  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
95.3  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
5  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
XLogP3:
-1.1  

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Title: Impact of dronedarone in atrial fibrillation and flutter on stroke reduction.

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Title: Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.

Journal: European journal of medicinal chemistry 20090901

Title: Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activities.

Journal: Bioorganic & medicinal chemistry 20090815

Title: Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer.

Journal: British journal of cancer 20090804

Title: Synthesis, anticancer, and anti-inflammatory activity evaluation of methanesulfonamide and amidine derivatives of 3,4-diaryl-2-imino-4-thiazolines.

Journal: Molecular diversity 20090801

Title: Development and validation of an LC-MS/MS method for determination of methanesulfonamide in human urine.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715

Title: Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinediones.

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Title: Methanesulfonamide: a cosolvent and a general acid catalyst in sharpless asymmetric dihydroxylations.

Journal: The Journal of organic chemistry 20090417

Title: Cytotoxic activity of platinum(II) and palladium(II) complexes of N-3-pyridinylmethanesulfonamide: the influence of electroporation.

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Title: An experimental and theoretical study of dipole moments of N-[4-(9-acridinylamino)-3-methoxyphenyl]methanesulfonamide.

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Title: Optimization of triaryl bis-sulfones as cannabinoid-2 receptor ligands.

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Title: A single component ratiometric pH probe with long wavelength excitation of europium emission.

Journal: Chemical communications (Cambridge, England) 20070207

Title: Synthesis and biological evaluation of methanesulfonamide analogues of rofecoxib: Replacement of methanesulfonyl by methanesulfonamido decreases cyclooxygenase-2 selectivity.

Journal: Bioorganic & medicinal chemistry 20070115

Title: Inhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agents.

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Title: Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.

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Title: Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxysulfamides--a new zinc-binding function in the design of inhibitors.

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Title: Methanesulfonamide group at position-4 of the C-5-phenyl ring of 1,5-diarylpyrazole affords a potent class of cyclooxygenase-2 (COX-2) inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20040405

Title: N-4-Substituted-benzyl-N'-tert-butylbenzyl thioureas as vanilloid receptor ligands: investigation on the role of methanesulfonamido group in antagonistic activity.

Journal: Bioorganic & medicinal chemistry letters 20040209

Title: Differential recovery of action potential duration and HERG currents from the effects of two methanesulfonamide class III antiarrhythmic agents, KCB-328 and dofetilide.

Journal: Journal of cardiovascular pharmacology 20031101

Title: Variations of acidic functions at position 2 and substituents at positions 4, 5 and 6 of the indole moiety and their effect on NMDA-glycine site affinity.

Journal: European journal of medicinal chemistry 20031001

Title: Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion.

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Title: Substituted indole-5-carboxamides and -acetamides as potent nonpeptide GnRH receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20010709

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