Home Other Building Blocks 315-72-0
315-72-0,MFCD00865455
Catalog No.:AA01CBU2

315-72-0 | 1-Piperazineethanol, 4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$56.00   $39.00
- +
10mg
≥98%
in stock  
$100.00   $70.00
- +
25mg
≥98%
in stock  
$218.00   $152.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01CBU2
Chemical Name:
1-Piperazineethanol, 4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-
CAS Number:
315-72-0
Molecular Formula:
C23H29N3O
Molecular Weight:
363.4959
MDL Number:
MFCD00865455
SMILES:
OCCN1CCN(CC1)CCCN1c2ccccc2C=Cc2c1cccc2
NSC Number:
169867
Properties
Properties
 
Form:
Solid  
MP:
94-97℃  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
448  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
3.6  

Literature

Title: Opipramol dihydro-chloride.

Journal: Acta crystallographica. Section E, Structure reports online 20111101

Title: Opipramolium fumarate.

Journal: Acta crystallographica. Section E, Structure reports online 20110901

Title: Clinical outcome of a headache-specific multidisciplinary treatment program and adherence to treatment recommendations in a tertiary headache center: an observational study.

Journal: The journal of headache and pain 20110801

Title: Opipramol.

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Molecular recognition of the antiretroviral drug abacavir: towards the development of a novel carbazole-based fluorosensor.

Journal: Journal of fluorescence 20110501

Title: Antidepressant use and colorectal cancer risk: a Danish population-based case-control study.

Journal: British journal of cancer 20110104

Title: Opipramol improves subjective quality of sleep the night prior to surgery: confirmatory testing of a double-blind, randomized clinical trial.

Journal: Neuropsychobiology 20110101

Title: Complete Long-Term Remission of an Inflammatory Pseudotumor under Corticosteroid Therapy.

Journal: Case reports in oncology 20110101

Title: Marked mydriasis and neuritis nervi optici associated with galactorrhea following citalopram treatment: a case report and discussion.

Journal: Case reports in medicine 20110101

Title: Reduction of claustrophobia with short-bore versus open magnetic resonance imaging: a randomized controlled trial.

Journal: PloS one 20110101

Title: Generalised anxiety disorder.

Journal: BMJ clinical evidence 20110101

Title: Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays.

Journal: PloS one 20110101

Title: Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease.

Journal: Annals of neurology 20101101

Title: In vitro studies of DNA damage caused by tricyclic antidepressants: a role of peroxidase in the side effects of the drugs.

Journal: Chemical research in toxicology 20100920

Title: Opipramol dipicrate.

Journal: Acta crystallographica. Section E, Structure reports online 20100801

Title: Determination of the chemical structure of potential organic impurities occurring in the drug substance opipramol.

Journal: Die Pharmazie 20100401

Title: Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.

Journal: Nutrition journal 20100101

Title: Tricyclic antidepressants and headaches: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.) 20100101

Title: Binding of imipramine, dosulepin, and opipramol to liposomes for overdose treatment.

Journal: Journal of pharmaceutical sciences 20091001

Title: The sigma-1 antagonist BMY-14802 inhibits L-DOPA-induced abnormal involuntary movements by a WAY-100635-sensitive mechanism.

Journal: Psychopharmacology 20090701

Title: Gastroprotective and antioxidant effects of opipramol on indomethacin-induced ulcers in rats.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090701

Title: Opipramol as nighttime medication.

Journal: Deutsches Arzteblatt international 20090501

Title: Magnitude of potentially inappropriate prescribing in Germany among older patients with generalized anxiety disorder.

Journal: BMC geriatrics 20090101

Title: sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20081101

Title: Optimizing prophylactic treatment of migraine: Subtypes and patient matching.

Journal: Therapeutics and clinical risk management 20081001

Title: Frequency of different anti-depressants associated with suicides and drug deaths.

Journal: International journal of legal medicine 20080301

Title: [Pathologic worry].

Journal: MMW Fortschritte der Medizin 20071115

Title: [Generalized anxiety disorder (GAD)--diagnosis and therapy].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20071101

Title: Generalised anxiety disorder.

Journal: BMJ clinical evidence 20070101

Title: Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020

Title: A retrospective analysis of antidepressant poisonings in the emergency department: 11-year experience.

Journal: Human & experimental toxicology 20061001

Title: [Trazodone for the treatment of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease: a retrospective study focused on the aggression and negativism in caregiving situations].

Journal: No to shinkei = Brain and nerve 20060601

Title: Induction of a mixed depressive episode during rTMS treatment in a patient with refractory major depression.

Journal: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20060101

Title: Anti-proliferative activity of haloperidol in B16 mouse and human SK-MEL-28 melanoma cell lines.

Journal: International journal of oncology 20051001

Title: Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.

Journal: Journal of medicinal chemistry 20050728

Title: Combined pH/organic solvent gradient HPLC in analysis of forensic material.

Journal: Journal of pharmaceutical and biomedical analysis 20050429

Title: 2,2'-Bipyridine as a new and sensitive spectrophotometric reagent for the determination of nanoamounts of certain dibenzazepine class of tricyclic antidepressant drugs.

Journal: Farmaco (Societa chimica italiana : 1989) 20050101

Title: Neuropharmacology of the anxiolytic drug opipramol, a sigma site ligand.

Journal: Pharmacopsychiatry 20041101

Title: Clinical trials with sigma ligands.

Journal: Pharmacopsychiatry 20041101

Title: [Somatoform disorders--what must the general practitioner know?].

Journal: MMW Fortschritte der Medizin 20040819

Title: Urine sample preparation of tricyclic antidepressants by means of a supported liquid membrane technique for high-performance liquid chromatographic analysis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040305

Title: Therapeutic drug monitoring of 13 antidepressant and five neuroleptic drugs in serum with liquid chromatography-electrospray ionization mass spectrometry.

Journal: Clinical chemistry and laboratory medicine 20031201

Title: Specific modulation of sigma binding sites by the anxiolytic drug opipramol.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20031001

Title: Bioavailability of opipramol from a film-coated tablet, a sugar-coated tablet and an aqueous solution in healthy volunteers.

Journal: Arzneimittel-Forschung 20030101

Title: Kava-Kava extract LI 150 is as effective as Opipramol and Buspirone in Generalised Anxiety Disorder--an 8-week randomized, double-blind multi-centre clinical trial in 129 out-patients.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20030101

Title: The treatment of generalised anxiety disorder. A systematic review.

Journal: Panminerva medica 20021201

Title: Simultaneous determination of seven tricyclic antidepressant drugs in human plasma by direct-injection HPLC-APCI-MS-MS with an ion trap detector.

Journal: Therapeutic drug monitoring 20020801

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Effects of opipramol as an evening anaesthesiologic premedication.

Journal: Neuropsychobiology 20020101

Title: Determination of opipramol in human plasma by high-performance liquid chromatography with photometric detection using a cyanopropyl column.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010405

Title: Opipramol for the treatment of generalized anxiety disorder: a placebo-controlled trial including an alprazolam-treated group.

Journal: Journal of clinical psychopharmacology 20010201

Title: Some central effects of opipramol given repeatedly.

Journal: Polish journal of pharmacology and pharmacy 19900101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:315-72-0 Molecular Formula|315-72-0 MDL|315-72-0 SMILES|315-72-0 1-Piperazineethanol, 4-[3-(5H-dibenz[b,f]azepin-5-yl)propyl]-