Title: Effects of mycophenolic acid alone and in combination with its metabolite mycophenolic acid glucuronide on rat embryos in vitro.
Journal: Archives of toxicology 20130201
Title: Omeprazole impairs the absorption of mycophenolate mofetil but not of enteric-coated mycophenolate sodium in healthy volunteers.
Journal: Journal of clinical pharmacology 20120801
Title: Liquid chromatography-tandem mass spectrometry method for the quantification of mycophenolic acid and its phenolic glucuronide in saliva and plasma using a standardized saliva collection device.
Journal: Journal of chromatography. A 20120608
Title: Development of population PK model with enterohepatic circulation for mycophenolic acid in patients with childhood-onset systemic lupus erythematosus.
Journal: British journal of clinical pharmacology 20120501
Title: Effective plasma concentrations of mycophenolic acid and its glucuronide in systemic lupus erythematosus patients in the remission-maintenance phase.
Journal: Journal of clinical pharmacy and therapeutics 20120401
Title: Human α/β hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver.
Journal: The Journal of biological chemistry 20120316
Title: A high-throughput U-HPLC-MS/MS assay for the quantification of mycophenolic acid and its major metabolites mycophenolic acid glucuronide and mycophenolic acid acyl-glucuronide in human plasma and urine.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120201
Title: Pharmacokinetics of tacrolimus and mycophenolate mofetil in renal transplant recipients on a corticosteroid-free regimen.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120115
Title: Renal graft function and low-dose cyclosporine affect mycophenolic acid pharmacokinetics in kidney transplantation.
Journal: Transplantation 20110915
Title: Mycophenolic acid pharmacokinetics during maintenance immunosuppression in African American and Caucasian renal transplant recipients.
Journal: Journal of clinical pharmacology 20110801
Title: Cyclosporine alters correlation between free and total mycophenolic acid in kidney transplant recipients in the initial phase.
Journal: Journal of clinical pharmacy and therapeutics 20110401
Title: UPLC MS/MS method for quantification of mycophenolic acid and metabolites in human plasma: Application to pharmacokinetic study.
Journal: Clinica chimica acta; international journal of clinical chemistry 20110114
Title: Simultaneous determination of mycophenolic acid and its metabolites by HPLC and pharmacokinetic studies in rat plasma and bile.
Journal: Archives of pharmacal research 20110101
Title: [Optimal immunosuppressive therapy based on pharmacokinetics and pharmacodynamics of antimetabolites in clinical practice].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101201
Title: Neither mycophenolate acyl-glucuronide levels nor their areas under the curve are responsible for the gastrointestinal side effects in kidney transplant recipients receiving EC-MPA: a prospective trial.
Journal: Transplantation proceedings 20101201
Title: Establishment of high-performance liquid chromatography and enzyme multiplied immunoassay technology methods for determination of free mycophenolic acid and its application in Chinese liver transplant recipients.
Journal: Therapeutic drug monitoring 20101001
Title: Sample cleanup-free determination of mycophenolic acid and its glucuronide in serum and plasma using the novel technology of ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry.
Journal: Talanta 20100315
Title: Mycophenolate pharmacokinetics and association with response to acute graft-versus-host disease treatment from the Blood and Marrow Transplant Clinical Trials Network.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100301
Title: Pharmacogenetic influences on mycophenolate therapy.
Journal: Pharmacogenomics 20100301
Title: Inhibition of intestinal and hepatic glucuronidation of mycophenolic acid by Ginkgo biloba extract and flavonoids.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201
Title: Investigation of the crossreactivity of mycophenolic acid glucuronide metabolites and of mycophenolate mofetil in the Cedia MPA assay.
Journal: Therapeutic drug monitoring 20100201
Title: Monitoring of mycophenolate acid in serum or plasma using LC tandem mass spectrometry.
Journal: Methods in molecular biology (Clifton, N.J.) 20100101
Title: High-performance liquid chromatography-mass spectroscopy/mass spectroscopy method for simultaneous quantification of total or free fraction of mycophenolic acid and its glucuronide metabolites.
Journal: Therapeutic drug monitoring 20091201
Title: Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients.
Journal: Journal of pharmacokinetics and pharmacodynamics 20091201
Title: Bioavailability of mycophenolate mofetil and enteric-coated mycophenolate sodium is differentially affected by pantoprazole in healthy volunteers.
Journal: Journal of clinical pharmacology 20091001
Title: Optimal mycophenolic acid and mycophenolic acid glucuronide levels at the early period after kidney transplantation are the key contributors to improving long-term outcomes.
Journal: Transplantation proceedings 20091001
Title: Mechanism-based enterohepatic circulation model of mycophenolic acid and its glucuronide metabolite: assessment of impact of cyclosporine dose in Asian renal transplant patients.
Journal: Journal of clinical pharmacology 20090601
Title: Impact of calcineurin inhibitors on urinary excretion of mycophenolic acid and its glucuronide in kidney transplant recipients.
Journal: Journal of clinical pharmacology 20090601
Title: Influence of clinical and demographic variables on mycophenolic acid pharmacokinetics in antineutrophil cytoplasmic antibody-associated vasculitis.
Journal: The Annals of pharmacotherapy 20090601
Title: Cyclosporine concentration-dependent increase in concentration ratio of mycophenolic acid acyl and phenol glucuronides to mycophenolic acid in stable kidney transplant recipients.
Journal: Clinical biochemistry 20090501
Title: Effect of mycophenolate acyl-glucuronide on human recombinant type 2 inosine monophosphate dehydrogenase.
Journal: Clinical chemistry 20090501
Title: Measurement of mycophenolic acid and its glucuronide using a novel rapid liquid chromatography-electrospray ionization tandem mass spectrometry assay.
Journal: Clinical biochemistry 20090101
Title: Pharmacokinetics of mycophenolic acid in patients with lupus nephritis.
Journal: Pharmacotherapy 20090101
Title: The role of pH in the glucuronidation of raloxifene, mycophenolic acid and ezetimibe.
Journal: Molecular pharmaceutics 20090101
Title: Limited sampling models and Bayesian estimation for mycophenolic acid area under the curve prediction in stable renal transplant patients co-medicated with ciclosporin or sirolimus.
Journal: Clinical pharmacokinetics 20090101
Title: Comparison of pharmacokinetics of mycophenolic acid and its glucuronide between patients with lupus nephritis and with kidney transplantation.
Journal: Therapeutic drug monitoring 20081201
Title: Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20081101
Title: Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.
Journal: Therapeutic drug monitoring 20081001
Title: AcylMPAG plasma concentrations and mycophenolic acid-related side effects in patients undergoing renal transplantation are not related to the UGT2B7-840G>A gene polymorphism.
Journal: Therapeutic drug monitoring 20080801
Title: Application of experimental design in optimization of solid phase extraction of mycophenolic acid and mycophenolic acid glucuronide from human urine and plasma and SPE-RP-HPLC method validation.
Journal: Journal of pharmaceutical and biomedical analysis 20080715
Title: Determination of mycophenolic acid glucuronide in microsomal incubations using high performance liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080715
Title: The impact of P-glycoprotein and Mrp2 on mycophenolic acid levels in mice.
Journal: Transplant immunology 20080701
Title: Pharmacokinetics of mycophenolic acid in live donor liver transplant patients vs deceased donor liver transplant patients.
Journal: Journal of clinical pharmacology 20080501
Title: Simultaneous determination of mycophenolic acid and its glucuronides in human plasma using isocratic ion pair high-performance liquid chromatography.
Journal: Journal of pharmaceutical and biomedical analysis 20080213
Title: Evaluation of MPA and MPAG removal by continuous venovenous hemodiafiltration and continuous venovenous hemofiltration.
Journal: Therapeutic drug monitoring 20080201
Title: Glucuronidation of mycophenolic acid by Wistar and Mrp2-deficient TR- rat liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080101
Title: Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients: a pilot study.
Journal: Clinical transplantation 20080101
Title: Lack of association between common polymorphisms in UGT1A9 and gene expression and activity.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20071201
Title: Liquid chromatographic determination of mycophenolic acid and its metabolites in human kidney transplant plasma: pharmacokinetic application.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071115
Title: Simultaneous determination of cortisol, dexamethasone, methylprednisolone, prednisone, prednisolone, mycophenolic acid and mycophenolic acid glucuronide in human plasma utilizing liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101
Title: Methanol-associated matrix effects in electrospray ionization tandem mass spectrometry.
Journal: Clinical chemistry 20071001
Title: Influence of renal insufficiency on pharmacokinetics of ACYL-glucuronide metabolite of mycophenolic acid in renal transplant patients.
Journal: Transplantation proceedings 20070901
Title: The impact of renal allograft function on exposure and elimination of mycophenolic acid (MPA) and its metabolite MPA 7-O-glucuronide.
Journal: Transplantation 20070815
Title: Plasma concentrations of mycophenolic acid acyl glucuronide are not associated with diarrhea in renal transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070701
Title: Interaction and transport characteristics of mycophenolic acid and its glucuronide via human organic anion transporters hOAT1 and hOAT3.
Journal: Biochemical pharmacology 20070630
Title: Relationship between MPA free fraction and free MPAG concentrations in heart transplant recipients based on simultaneous HPLC quantification of the target compounds in human plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601
Title: Influence of the UGT2B7 promoter region and exon 2 polymorphisms and comedications on Acyl-MPAG production in vitro and in adult renal transplant patients.
Journal: Pharmacogenetics and genomics 20070501
Title: Gender-related differences in mycophenolate mofetil-induced gastrointestinal toxicity in rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301
Title: Concentrations of mycophenolic acid and glucuronide metabolites under concomitant therapy with cyclosporine or tacrolimus.
Journal: Therapeutic drug monitoring 20070201
Title: Total and free mycophenolic acid and its 7-O-glucuronide metabolite in Chinese adult renal transplant patients: pharmacokinetics and application of limited sampling strategies.
Journal: European journal of clinical pharmacology 20070101
Title: Bioequivalence of enteric-coated mycophenolate sodium and mycophenolate mofetil: a meta-analysis of three studies in stable renal transplant recipients.
Journal: Transplantation 20061215
Title: Rifampin induces alterations in mycophenolic acid glucuronidation and elimination: implications for drug exposure in renal allograft recipients.
Journal: Clinical pharmacology and therapeutics 20061101
Title: Quantification by liquid chromatography tandem mass spectrometry of mycophenolic acid and its phenol and acyl glucuronide metabolites.
Journal: Clinical chemistry 20061001
Title: Characterization of intestinal absorption and enterohepatic circulation of mycophenolic Acid and its 7-O-glucuronide in rats.
Journal: Drug metabolism and pharmacokinetics 20061001
Title: Influence of nonsynonymous polymorphisms of UGT1A8 and UGT2B7 metabolizing enzymes on the formation of phenolic and acyl glucuronides of mycophenolic acid.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060901
Title: Characterization of rat intestinal microsomal UDP-glucuronosyltransferase activity toward mycophenolic acid.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060901
Title: Pharmacokinetics of mycophenolic acid and its glucuronidated metabolites in stable lung transplant recipients.
Journal: The Annals of pharmacotherapy 20060901
Title: Absorption characteristics of EC-MPS--an enteric-coated formulation of mycophenolic sodium.
Journal: International journal of clinical pharmacology and therapeutics 20060801
Title: Adsorption of mycophenolic acid and its phenolic glucuronide to glass, polystyrene, and polypropylene containers.
Journal: Clinical chemistry 20060501
Title: [Pharmacokinetic model for the enterohepatic circulation of mycophenolic acid].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060301
Title: Effects of calcineurin inhibitors on pharmacokinetics of mycophenolic acid and its glucuronide metabolite during the maintenance period following renal transplantation.
Journal: Biological & pharmaceutical bulletin 20060201
Title: Comparison of mycophenolic acid pharmacokinetic parameters in kidney transplant patients within the first 3 months post-transplant.
Journal: Journal of clinical pharmacy and therapeutics 20060201
Title: Pharmacokinetics of enteric-coated mycophenolate sodium in stable pediatric renal transplant recipients.
Journal: Pediatric transplantation 20051201
Title: Trough levels of mycophenolic acid and its glucuronidated metabolite in renal transplant recipients.
Journal: International journal of clinical pharmacology and therapeutics 20050801
Title: Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
Title: Enteric-coated mycophenolate sodium delivers bioequivalent MPA exposure compared with mycophenolate mofetil.
Journal: Clinical transplantation 20050401
Title: Pharmacokinetics of tacrolimus and mycophenolic acid are altered, but recover at different times during hepatic regeneration in rats.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050301
Title: Mycophenolic acid pharmacokinetics and related outcomes early after renal transplant.
Journal: British journal of clinical pharmacology 20050301
Title: Standard dose enteric-coated mycophenolate sodium (myfortic) delivers rapid therapeutic mycophenolic acid exposure in kidney transplant recipients.
Journal: Transplantation proceedings 20050301
Title: Intraindividual and interindividual variations in the pharmacokinetics of mycophenolic acid in liver transplant patients.
Journal: Journal of clinical pharmacology 20050101
Title: HPLC determination of mycophenolic acid and mycophenolic acid glucuronide in human plasma with hybrid material.
Journal: Journal of pharmaceutical and biomedical analysis 20041115
Title: Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20040601
Title: Development of a high pressure liquid chromatography method for the determination of mycophenolic acid and its glucuronide metabolite in small volumes of plasma from paediatric patients.
Journal: Journal of pharmaceutical and biomedical analysis 20040401
Title: Pharmacokinetics of daclizumab and mycophenolate mofetil with cyclosporine and steroids in renal transplantation.
Journal: Clinical transplantation 20031201
Title: Twelve-month evaluation of the clinical pharmacokinetics of total and free mycophenolic acid and its glucuronide metabolites in renal allograft recipients on low dose tacrolimus in combination with mycophenolate mofetil.
Journal: Therapeutic drug monitoring 20031001
Title: High-performance liquid chromatographic method for mycophenolic acid and its glucuronide in serum and urine.
Journal: Journal of clinical pharmacy and therapeutics 20030201
Title: Mycophenolic acid and mycophenolic acid glucuronide pharmacokinetics in pediatric liver transplant recipients: effect of cyclosporine and tacrolimus comedication.
Journal: Therapeutic drug monitoring 20021001
Title: Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients.
Journal: Therapeutic drug monitoring 20020601
Title: In vivo higher glucuronidation of mycophenolic acid in male than in female recipients of a cadaveric kidney allograft and under immunosuppressive therapy with mycophenolate mofetil.
Journal: Therapeutic drug monitoring 20011001
Title: Rapid and simultaneous determination of mycophenolic acid and its glucuronide conjugate in human plasma by ion-pair reversed-phase high-performance liquid chromatography using isocratic elution.
Journal: Journal of chromatography. B, Biomedical sciences and applications 20010405
Title: Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes.
Journal: British journal of pharmacology 20010301
Title: Pharmacokinetics of mycophenolic acid after mycophenolate mofetil administration in liver transplant patients treated with tacrolimus.
Journal: Journal of clinical pharmacology 20010301
Title: The acyl glucuronide metabolite of mycophenolic acid inhibits the proliferation of human mononuclear leukocytes.
Journal: Transplantation proceedings 20010101
