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315698-36-3,MFCD02330713
Catalog No.:AA00CNEN

315698-36-3 | MLS1547

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
95%
in stock  
$90.00   $63.00
- +
50mg
≥98%(HPLC)
in stock  
$747.00   $523.00
- +
100mg
≥98%(HPLC)
in stock  
$1,259.00   $882.00
- +
500mg
in stock  
$3,958.00   $2,771.00
- +
1000mg
in stock  
$6,295.00   $4,407.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00CNEN
Chemical Name:
MLS1547
CAS Number:
315698-36-3
Molecular Formula:
C19H19ClN4O
Molecular Weight:
354.8334
MDL Number:
MFCD02330713
SMILES:
Clc1cc(CN2CCN(CC2)c2ccccn2)c(c2c1cccn2)O
Properties
Computed Properties
 
Complexity:
432  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3.2  

Literature

Title: Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.

Journal: Molecular pharmacology 20140701

Title: Derivatives of 8-hydroxyquinoline--antibacterial agents that target intra- and extracellular Gram-negative pathogens.

Journal: Bioorganic & medicinal chemistry letters 20120515

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Free RB, et al. Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor. Mol Pharmacol. 2014;86(1):96-105.

Title: Chun LS, et al. Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor. Front Synaptic Neurosci. 2018;10:2. Published 2018 Feb 21.

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