Title: Antiplatelet treatment in primary and secondary stroke prevention in women.
Journal: European journal of internal medicine 20121001
Title: Non-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium?
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120301
Title: Review of atrial fibrillation outcome trials of oral anticoagulant and antiplatelet agents.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120301
Title: Antithrombotic and thrombolytic therapy for ischemic stroke: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Journal: Chest 20120201
Title: Using functional signatures to identify repositioned drugs for breast, myelogenous leukemia and prostate cancer.
Journal: PLoS computational biology 20120201
Title: Effect of pharmacological therapies for stroke prevention on major gastrointestinal bleeding in patients with atrial fibrillation.
Journal: International journal of clinical practice 20120101
Title: Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice.
Journal: Journal of neuroinflammation 20120101
Title: Aspirin prophylaxis for the prevention of thrombosis: expectations and limitations.
Journal: Thrombosis 20120101
Title: Preventing stroke in atrial fibrillation patients - clinical utility of oral anticoagulants.
Journal: Journal of blood medicine 20120101
Title: Recommendations for management of patients with carotid stenosis.
Journal: Stroke research and treatment 20120101
Title: A phase I study to characterize the multiple-dose pharmacokinetics, pharmacodynamics and safety of new enteric-coated triflusal formulations in healthy male volunteers.
Journal: Expert opinion on drug metabolism & toxicology 20111201
Title: Gastrointestinal safety of triflusal solution in healthy volunteers: a proof of concept endoscopic study.
Journal: European journal of clinical pharmacology 20110701
Title: Antiagregation and anticoagulation, relationship with upper gastrointestinal bleeding.
Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20110701
Title: Letter by Borja and Garcia-Rafanell regarding article, 'Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association'.
Journal: Stroke 20110601
Title: Two cases of h(2)-receptor antagonist hypersensitivity and cross-reactivity.
Journal: Allergy, asthma & immunology research 20110401
Title: Regular physical exercise training assists in preventing type 2 diabetes development: focus on its antioxidant and anti-inflammatory properties.
Journal: Cardiovascular diabetology 20110101
Title: Effect of the dual endothelin receptor antagonist bosentan on untreatable skin ulcers in a patient with diabetes: a case report.
Journal: Journal of medical case reports 20110101
Title: Antiplatelets in secondary stroke prevention.
Journal: Frontiers in neurology 20110101
Title: Comparative effects of triflusal, S-adenosylmethionine, and dextromethorphan over intestinal ischemia/reperfusion injury.
Journal: TheScientificWorldJournal 20110101
Title: Optimal management of peripheral arterial disease for the non-specialist.
Journal: The Ulster medical journal 20110101
Title: Triflusal reduces cerebral ischemia induced inflammation in a combined mouse model of Alzheimer's disease and stroke.
Journal: Brain research 20101217
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Bioactive polymeric systems with platelet antiaggregating activity for the coating of vascular devices.
Journal: Biomacromolecules 20101011
Title: Oral antiplatelet therapy in stroke prevention. Minireview.
Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20100901
Title: Electrochemical behavior of triflusal, aspirin and their metabolites at glassy carbon and boron doped diamond electrodes.
Journal: Combinatorial chemistry & high throughput screening 20100801
Title: Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease.
Journal: Neurobiology of disease 20100601
Title: Thinking outside the box about COX-1 in Alzheimer's disease.
Journal: Neurobiology of disease 20100601
Title: Update on antithrombotic therapy for stroke prevention in atrial fibrillation.
Journal: Current treatment options in cardiovascular medicine 20100601
Title: Thrombi of different pathologies: implications for diagnosis and treatment.
Journal: Current treatment options in cardiovascular medicine 20100601
Title: In vitro and in vivo performance of a dual drug-eluting stent (DDES).
Journal: Biomaterials 20100501
Title: Influence of antiplatelet pre-treatment on the risk of intracranial haemorrhage in acute ischaemic stroke after intravenous thrombolysis.
Journal: European journal of neurology 20100201
Title: Comparative bioavailability study of triflusal oral solution vs. triflusal capsules in healthy subjects. A single, randomized, two-way cross-over, open-label phase I study.
Journal: Arzneimittel-Forschung 20100101
Title: Study on QSTR of benzoic acid compounds with MCI.
Journal: International journal of molecular sciences 20100101
Title: Triple antiplatelet therapy for preventing vascular events: a systematic review and meta-analysis.
Journal: BMC medicine 20100101
Title: Presenilin/gamma-Secretase and Inflammation.
Journal: Frontiers in aging neuroscience 20100101
Title: Eicosanoids in the innate immune response: TLR and non-TLR routes.
Journal: Mediators of inflammation 20100101
Title: Prevention strategies for cardioembolic stroke: present and future perspectives.
Journal: The open neurology journal 20100101
Title: Are NSAIDs useful to treat Alzheimer's disease or mild cognitive impairment?
Journal: Frontiers in aging neuroscience 20100101
Title: Is there an association between low dose aspirin and anemia (without overt bleeding)? Narrative review.
Journal: BMC geriatrics 20100101
Title: Staging anti-inflammatory therapy in Alzheimer's disease.
Journal: Frontiers in aging neuroscience 20100101
Title: Addressing the challenges to successful recruitment and retention in Alzheimer's disease clinical trials.
Journal: Alzheimer's research & therapy 20100101
Title: Comparison of triple antiplatelet therapy including triflusal and conventional dual therapy in patients who underwent drug-eluting stent implantation.
Journal: International heart journal 20091101
Title: The short-term effect on restenosis and thrombosis of a cobalt-chromium stent eluting two drugs in a porcine coronary artery model.
Journal: Journal of interventional cardiology 20091001
Title: Long-term follow-up of atrial fibrillation patients in the NASPEAF study. Prospective evaluation of different antiplatelet treatments.
Journal: Revista espanola de cardiologia 20090901
Title: Neuroprotective effects of the anti-inflammatory compound triflusal on ischemia-like neurodegeneration in mouse hippocampal slice cultures occur independent of microglia.
Journal: Experimental neurology 20090701
Title: Photonucleophilic addition of the epsilon-amino group of lysine to a triflusal metabolite as a mechanistic key to photoallergy mediated by the parent drug.
Journal: ChemMedChem 20090701
Title: Mechanism-based treatments for Alzheimer's disease.
Journal: Dialogues in clinical neuroscience 20090601
Title: Effect of age on stroke prevention therapy in patients with atrial fibrillation: the atrial fibrillation investigators.
Journal: Stroke 20090401
Title: [Resistance to triflusal or an insufficient dose?].
Journal: Revista de neurologia 20090401
Title: Triflusal: an old drug in modern antiplatelet therapy. Review of its action, use, safety and effectiveness.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20090101
Title: Triflusal and aspirin have different effects on inflammatory biomarkers measured in patients with acute ischemic stroke.
Journal: Cerebrovascular diseases (Basel, Switzerland) 20090101
Title: Protective effects of triflusal on secondary thrombus growth and vascular cyclooxygenase-2.
Journal: Journal of thrombosis and haemostasis : JTH 20080801
Title: Salicylates increase insulin secretion in healthy obese subjects.
Journal: The Journal of clinical endocrinology and metabolism 20080701
Title: Spectroscopic and chromatographic characterization of triflusal delivery systems prepared by using supercritical impregnation technologies.
Journal: Journal of pharmaceutical and biomedical analysis 20080213
Title: Safety of triflusal (antiplatelet drug) in patients with aspirin-exacerbated respiratory diseases.
Journal: Allergy 20080101
Title: The inflammatory hypothesis of Alzheimer disease: dead or alive?
Journal: Alzheimer disease and associated disorders 20080101
Title: A randomized, double-blind, placebo controlled-trial of triflusal in mild cognitive impairment: the TRIMCI study.
Journal: Alzheimer disease and associated disorders 20080101
Title: Bioequivalence of two oral formulations of triflusal capsules in healthy volunteers.
Journal: Arzneimittel-Forschung 20080101
Title: Inflammaging as a prodrome to Alzheimer's disease.
Journal: Journal of neuroinflammation 20080101
Title: Amiodarone-induced hepatitis and polyneuropathy.
Journal: The Korean journal of internal medicine 20070901
Title: The study of the influence of surfactant charge on alkaline hydrolysis reactions of acetylsalicylic acid (ASA) and triflusal (TFL) using spectrophotometric methods.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070701
Title: Effects of triflusal and aspirin in a rat model of cerebral ischemia.
Journal: Stroke 20070201
Title: [Trend in platelet antiaggregants utilization in the autonomous community of Valencia, Spain (2000-2005)].
Journal: Revista espanola de salud publica 20070101
Title: Use of aspirin for primary and secondary prevention of cardiovascular disease in diabetic patients in an ambulatory care setting in Spain.
Journal: BMC family practice 20070101
Title: Antithrombotic treatment in atrial fibrillation.
Journal: Expert opinion on drug safety 20060901
Title: Antithrombotic treatment in atrial fibrillation. Response to: Bereznicki LR, Peterson GM, Jackson SL, Jeffrey EC: the risks of warfarin use in the elderly. Expert Opin. Drug Saf. (2006) 5(3):417-431.
Journal: Expert opinion on drug safety 20060701
Title: Platelet microparticles and platelet adhesion: therapeutic implications for the prevention and treatment of stroke.
Journal: Current treatment options in cardiovascular medicine 20060501
Title: Inhibition of cardiac hypertrophy by triflusal (4-trifluoromethyl derivative of salicylate) and its active metabolite.
Journal: Molecular pharmacology 20060401
Title: Upper gastrointestinal bleeding associated with antiplatelet drugs.
Journal: Alimentary pharmacology & therapeutics 20060115
Title: Triflusal: a review of its use in cerebral infarction and myocardial infarction, and as thromboprophylaxis in atrial fibrillation.
Journal: Drugs 20060101
Title: Triflusal: an antiplatelet drug with a neuroprotective effect?
Journal: Cardiovascular drug reviews 20060101
Title: Platelet aggregation inhibitors in primary and secondary prevention of ischemic stroke.
Journal: GMS health technology assessment 20060101
Title: Inhibition of thromboxane biosynthesis by triflusal in type 2 diabetes mellitus.
Journal: Atherosclerosis 20051201
Title: Review of antiplatelet therapy in secondary prevention of cerebrovascular events: a need for direct comparisons between antiplatelet agents.
Journal: Journal of cardiovascular pharmacology and therapeutics 20050901
Title: Interaction between a rat model of cerebral ischemia and beta-amyloid toxicity: II. Effects of triflusal.
Journal: Stroke 20050801
Title: Triflusal for preventing serious vascular events in people at high risk.
Journal: The Cochrane database of systematic reviews 20050720
Title: Randomized clinical stroke trials in 2004.
Journal: Current atherosclerosis reports 20050701
Title: Triflusal versus oral anticoagulation for primary prevention of thromboembolism after bioprosthetic valve replacement (trac): prospective, randomized, co-operative trial.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050501
Title: Access of HTB, main metabolite of triflusal, to cerebrospinal fluid in healthy volunteers.
Journal: European journal of clinical pharmacology 20050401
Title: Oral antiplatelet therapy.
Journal: JAMA 20050216
Title: Protective effect of triflusal and its main metabolite HTB in an in vitro model of anoxia-reoxygenation in rat brain slices: comparison with acetylsalicylic and salicylic acids.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050101
Title: Adverse effects and drug interactions of antithrombotic agents used in prevention of ischaemic stroke.
Journal: Drugs 20050101
Title: A new pharmacological effect of salicylates: inhibition of NFAT-dependent transcription.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20041101
Title: Comparative effects of antiplatelet, anticoagulant, or combined therapy in patients with valvular and nonvalvular atrial fibrillation: a randomized multicenter study.
Journal: Journal of the American College of Cardiology 20041019
Title: Reconsidering combined antiplatelet and anticoagulant therapy in atrial fibrillation.
Journal: Journal of the American College of Cardiology 20041019
Title: Hydrophilic polymer drug from a derivative of salicylic acid: synthesis, controlled release studies and biological behavior.
Journal: Macromolecular bioscience 20040625
Title: Effects of triflusal on oxidative stress, prostaglandin production and nitric oxide pathway in a model of anoxia-reoxygenation in rat brain slices.
Journal: Brain research 20040618
Title: Aspirin: it's hard to beat.
Journal: Neurology 20040413
Title: Triflusal vs aspirin for prevention of cerebral infarction: a randomized stroke study.
Journal: Neurology 20040413
Title: Widespread eczema from triflusal confirmed by patch testing.
Journal: Contact dermatitis 20040401
Title: The stability of 2-acetoxy-4-trifluoromethylbenzoic acid (Triflusal) in micellar pseudophase.
Journal: Journal of pharmaceutical sciences 20040201
Title: Polymeric drugs with prolonged sustained delivery of specific anti-aggregant agents for platelets: kinetic analysis of the release mechanism.
Journal: Journal of biomaterials science. Polymer edition 20040101
Title: [Stroke and Other Thromboembolic Complications of Atrial Fibrillation. Part III. Prevention With Other Antithrombotic Agents.].
Journal: Kardiologiia 20040101
Title: Simultaneous determination of triflusal and its major active metabolite, 2-hydroxy-4-trifluoromethyl benzoic acid, in rat and human plasma by high-performance liquid chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031225
Title: Potential role of mitral valve strands on stroke recurrence in rheumatoid arthritis.
Journal: Arthritis and rheumatism 20031215
Title: Triflusal versus oral anticoagulation for primary prevention of thromboembolism after bioprosthetic valve replacement (TRAC): rationale and design for a prospective, randomized, co-operative trial.
Journal: Interactive cardiovascular and thoracic surgery 20030601
Title: Comparison of triflusal and aspirin for prevention of vascular events in patients after cerebral infarction: the TACIP Study: a randomized, double-blind, multicenter trial.
Journal: Stroke 20030401
Title: Can aspirin ever be surpassed for stroke prevention?
Journal: Stroke 20030401
Title: Risk of upper gastrointestinal bleeding associated with non-aspirin cardiovascular drugs, analgesics and nonsteroidal anti-inflammatory drugs.
Journal: European journal of gastroenterology & hepatology 20030201
Title: Decrease of proinflammatory molecules correlates with neuroprotective effect of the fluorinated salicylate triflusal after postnatal excitotoxic damage.
Journal: Stroke 20021001
Title: Compliance of geriatric patients subjected to antiplatelet agents with Triflusal in peripheral arteriopathy. Preliminary data.
Journal: Minerva cardioangiologica 20020601
Title: Platelet aggregation in different antithrombotic regimens. Possible proaggregant effect of low level oral anticoagulation.
Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20020501
Title: Economic evaluation of triflusal and aspirin in the treatment of acute myocardial infarction.
Journal: PharmacoEconomics 20020101
Title: Photopatch testing in seven cases of photosensitive drug eruptions.
Journal: The Annals of pharmacotherapy 20011201
Title: Triflusal posttreatment inhibits glial nuclear factor-kappaB, downregulates the glial response, and is neuroprotective in an excitotoxic injury model in postnatal brain.
Journal: Stroke 20011001
Title: Photochemistry of 2-hydroxy-4-trifluoromethylbenzoic acid, major metabolite of the photosensitizing platelet antiaggregant drug triflusal.
Journal: Photochemistry and photobiology 20010501
Title: Effect of 4-trifluoromethyl derivatives of salicylate on nuclear factor kappaB-dependent transcription in human astrocytoma cells.
Journal: British journal of pharmacology 20010101
Title: Randomized comparative trial of triflusal and aspirin following acute myocardial infarction.
Journal: European heart journal 20000301
Title: Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid.
Journal: Molecular pharmacology 19990401
Title: Fernández de Arriba A, et al. Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid. Mol Pharmacol. 1999 Apr;55(4):753-60.
Title: Duran, X., et al., Protective effects of triflusal on secondary thrombus growth and vascular cyclooxygenase-2. J Thromb Haemost, 2008. 6(8): p. 1385-92.
Title: De Miguel, L.S., et al., A 4-trifluoromethyl derivative of salicylate, triflusal, stimulates nitric oxide production by human neutrophils: role in platelet function. Eur J Clin Invest, 2000. 30(9): p. 811-7.