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32315-10-9,MFCD00062848
Catalog No.:AA0035P3

32315-10-9 | Triphosgene

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1g
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$18.00   $13.00
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25g
>98.0%(T)
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$108.00   $76.00
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250g
>98.0%(T)
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA0035P3
Chemical Name:
Triphosgene
CAS Number:
32315-10-9
Molecular Formula:
C3Cl6O3
Molecular Weight:
296.7483
MDL Number:
MFCD00062848
SMILES:
O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl
Properties
Properties
 
BP:
203-206 °C(lit.)  
Form:
Solid  
MP:
79-83 °C(lit.)  
Stability:
Moisture Sensitive  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
150  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
4.4  

Literature

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Title: Studies on the synthesis of derivatives of marine-derived bostrycin and their structure-activity relationship against tumor cells.

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Title: 5-Sulfanyl-idene-2H,5H-1,3-dithiolo[4,5-d][1,3]dithiol-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: [A study of the clinical features and the effect of therapy on acute respiratory distress syndrome patients as a result of severe triphosgene poisoning].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20120201

Title: Radiosynthesis of [13N]dantrolene, a positron emission tomography probe for breast cancer resistant protein, using no-carrier-added [13N]ammonia.

Journal: Bioorganic & medicinal chemistry 20120101

Title: N-(2,3,4-Trifluoro-phen-yl)pyrrolidine-1-carboxamide.

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Title: N-(2,3,4-Trifluoro-phen-yl)morpholine-4-carboxamide.

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Title: Degradable gene delivery systems based on Pluronics-modified low-molecular-weight polyethylenimine: preparation, characterization, intracellular trafficking, and cellular distribution.

Journal: International journal of nanomedicine 20120101

Title: Degradable polyethylenimine derivate coupled to a bifunctional peptide R13 as a new gene-delivery vector.

Journal: International journal of nanomedicine 20120101

Title: [Bis-(4-methyl-1,3-thia-zol-2-yl-κN)methane]-tricarbonyl-dichlorido-tungsten(II).

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Title: Gateway synthesis of daphnane congeners and their protein kinase C affinities and cell-growth activities.

Journal: Nature chemistry 20110801

Title: 3,8-Dimethyl-quinazoline-2,4(1H,3H)-dione.

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Title: Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4.

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Title: Diversity-oriented, one-pot, multi-component synthesis of substituted uracil derivatives.

Journal: Molecular diversity 20110201

Title: Acute nose-only inhalation exposure of rats to di- and triphosgene relative to phosgene.

Journal: Inhalation toxicology 20110201

Title: Bis(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl) carbonate.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: Nanoparticulate formulations of mithramycin analogs for enhanced cytotoxicity.

Journal: International journal of nanomedicine 20110101

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Journal: PLoS neglected tropical diseases 20100901

Title: 6-Chloro-8-methyl-4H-3,1-benzoxazine-2,4(1H)-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: Solid phase synthesis of hydrogen bond surrogate derived alpha-helices: resolving the case of a difficult amide coupling.

Journal: Organic & biomolecular chemistry 20100421

Title: Inhibitors of N(alpha)-acetyl-L-ornithine deacetylase: synthesis, characterization and analysis of their inhibitory potency.

Journal: Amino acids 20100401

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Journal: Acta crystallographica. Section E, Structure reports online 20100401

Title: Synthesis of 1,3-azaphosphol-2-ones. Crystal and molecular structures of [SP-4-2]-dichlorobis(3-phenyl-1,3-dihydrobenzo[1,3]azaphosphol-2-one-P)palladium(II) and its chloro(methyl)platinum(II) analogue.

Journal: Dalton transactions (Cambridge, England : 2003) 20100107

Title: Efficient synthesis of naphtho[1,2-e][1,3]oxazine derivatives via a chemoselective reaction with the aid of low-valent titanium reagent.

Journal: Journal of combinatorial chemistry 20100101

Title: Oriented synthesis and in vitro anticancer activity of biquinazoline-2,2'-diones.

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Title: Novel synthesis of N-alkoxycarbonyl amino acids and surfactant properties of their sodium salts.

Journal: Journal of oleo science 20100101

Title: Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.

Journal: Molecular cancer 20100101

Title: Simple, rapid, and highly sensitive detection of diphosgene and triphosgene by spectrophotometric methods.

Journal: Talanta 20091115

Title: Highly efficient synthesis of DNA-binding hairpin polyamides via the use of a new triphosgene coupling strategy.

Journal: Organic letters 20090903

Title: Synthesis of 3-N-sugar-substituted-2, 4(1H,3H)-quinazolinedionesas anti-angiogenesis agents.

Journal: Molecules (Basel, Switzerland) 20090708

Title: Cyclization of hydrazones of 2-acetyl-1-naphthol and 1-acetyl-2-naphthol with triphosgene. Synthesis of Spiro naphthoxazine dimers.

Journal: Molecules (Basel, Switzerland) 20090612

Title: The Amadori rearrangement as key reaction for the synthesis of neoglycoconjugates.

Journal: Carbohydrate research 20080811

Title: Synthesis and biological evaluation of a novel pentagastrin-toxin conjugate designed for a targeted prodrug mono-therapy of cancer.

Journal: International journal of molecular sciences 20080501

Title: Synthesis and in silico biological activity evaluation of new N-substituted pyrazolo-oxazin-2-one systems.

Journal: Bioorganic & medicinal chemistry 20080315

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Title: Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain.

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Title: Peptide immobilization on amine-terminated boron-doped diamond surfaces.

Journal: Langmuir : the ACS journal of surfaces and colloids 20070410

Title: A FRET approach to phosgene detection.

Journal: Chemical communications (Cambridge, England) 20070328

Title: First catalytic and green synthesis of aryl-(Z)-vinyl chlorides and its plausible addition-elimination mechanism.

Journal: Organic letters 20070315

Title: [Emergency treatment and nursing for patients with acute triphosgene poisoning].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20070301

Title: Synthesis and antimicrobial activity of new (4,4,4-trihalo-3-oxo-but-1-enyl)-carbamic acid ethyl esters, (4,4,4-trihalo-3-hydroxy-butyl)-carbamic acid ethyl esters, and 2-oxo-6-trihalomethyl-[1,3]oxazinane-3-carboxylic acid ethyl esters.

Journal: Bioorganic & medicinal chemistry 20060501

Title: Peptide crosslinked micelles: a new strategy for the design and synthesis of peptide vaccines.

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Title: Synthesis of hydantoins from enantiomerically pure alpha-amino amides without epimerization.

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Title: Functional analysis of backbone cyclic peptides bearing the arm domain of the HIV-1 Rev protein: characterization of the karyophilic properties and inhibition of Rev-induced gene expression.

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Title: Development of an efficient strategy for the synthesis of the ETB receptor antagonist BQ-788 and some related analogues.

Journal: Peptides 20050801

Title: Deazapurine solid-phase synthesis: combinatorial synthesis of a library of N3,N5,C6-trisubstituted pyrrolo[3,2-d]pyrimidine derivatives on cross-linked polystyrene bearing a cysteamine linker.

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Title: Synthesis of disubstituted imidazo[4,5-b]pyridin-2-ones.

Journal: The Journal of organic chemistry 20041029

Title: Novel fluoro- and hydroxyl-containing jasmonate derivatives as highly efficient elicitors in suspension cultures of Taxus chinensis.

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Title: Parallel solid-phase synthesis of disubstituted (5-biphenyltetrazolyl) hydantoins and thiohydantoins targeting the growth hormone secretagogue receptor.

Journal: Bioorganic & medicinal chemistry letters 20040119

Title: The use of solid-phase supported 1-N-piperazine-4-N-carboxaldehyde in Vilsmeier reactions.

Journal: Journal of combinatorial chemistry 20040101

Title: Debenzylation of tertiary amines using phosgene or triphosgene: an efficient and rapid procedure for the preparation of carbamoyl chlorides and unsymmetrical ureas. Application in carbon-11 chemistry.

Journal: The Journal of organic chemistry 20030919

Title: Selective cleavage of N-benzyl-protected secondary amines by triphosgene.

Journal: The Journal of organic chemistry 20030124

Title: Unexpected formation of an azetidine-carborane derivative by dehydration of N-(1,12-dicarba-closo-dodecaboran-1-yl)formamide. The first X-ray structure of a 2,3-bis(imino)azetidine.

Journal: Inorganic chemistry 20021202

Title: Complexation-induced unfolding of heterocyclic ureas. Simple foldamers equilibrate with multiply hydrogen-bonded sheetlike structures.

Journal: Journal of the American Chemical Society 20011031

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