Title: Preclinical assessment of the distribution, metabolism, and excretion of S-propargyl-cysteine, a novel H2S donor, in Sprague-Dawley rats.
Journal: Acta pharmacologica Sinica20120601
Title: S-propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuated tumor necrosis factor-α-induced inflammatory signaling and dysfunction in endothelial cells.
Journal: International journal of cardiology20120308
Title: Bioavailability and pharmacokinetics of S-propargyl-L-cysteine, a novel cardioprotective agent, after single and multiple doses in Beagle dogs.
Journal: Xenobiotica; the fate of foreign compounds in biological systems20120301
Title: Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice.
Journal: PloS one20120101
Title: Leonurine-cysteine analog conjugates as a new class of multifunctional anti-myocardial ischemia agent.
Journal: European journal of medicinal chemistry20110901
Title: S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.
Journal: Amino acids20110601
Title: Determination of S-propargyl-cysteine in rat plasma by mixed-mode reversed-phase and cation-exchange HPLC-MS/MS method and its application to pharmacokinetic studies.
Journal: Journal of pharmaceutical and biomedical analysis20110405
Title: S-propargyl-cysteine (ZYZ-802), a sulphur-containing amino acid, attenuates beta-amyloid-induced cognitive deficits and pro-inflammatory response: involvement of ERK1/2 and NF-κB pathway in rats.
Journal: Amino acids20110201
Title: S-propargyl-cysteine, a novel hydrogen sulfide-modulated agent, attenuates lipopolysaccharide-induced spatial learning and memory impairment: involvement of TNF signaling and NF-κB pathway in rats.
Journal: Brain, behavior, and immunity20110101
Title: H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S?
Journal: PloS one20110101
Title: Synthesis and biological evaluation of novel leonurine-SPRC conjugate as cardioprotective agents.
Journal: Bioorganic & medicinal chemistry letters20101201
Title: Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H(2)S production.
Journal: Antioxidants & redox signaling20100515
Title: S-propargyl-cysteine protects both adult rat hearts and neonatal cardiomyocytes from ischemia/hypoxia injury: the contribution of the hydrogen sulfide-mediated pathway.
Journal: Journal of cardiovascular pharmacology20090801
