Catalog No.:AA01E42Z

327056-26-8 | AZD9272

Name: Name:AZD9272
Brand: AABLOCKS
SKU: AA01E42Z
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

Quantity

5mg

≥98%

in stock

$152.00 $106.00

- +

10mg

≥98%

in stock

$283.00 $198.00

- +

25mg

≥98%

in stock

$668.00 $467.00

- +

Technical Information
Properties
Literature
Request for Quotation
Download SDS

Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA01E42Z

Chemical Name:

AZD9272

CAS Number:

327056-26-8

Molecular Formula:

C14H6F2N4O

Molecular Weight:

284.2204

MDL Number:

MFCD26394953

SMILES:

N#Cc1cc(F)cc(c1)c1onc(n1)c1ccc(cn1)F

Properties

Computed Properties

Complexity:

415

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Rotatable Bond Count:

XLogP3:

2.3

Literature

Title: Discovery and characterization of AZD9272 and AZD6538-Two novel mGluR5 negative allosteric modulators selected for clinical development.

Journal: Bioorganic & medicinal chemistry letters 20121115

Title: Swedberg MD, et al. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J Pharmacol Exp Ther. 2014 Aug;350(2):212-22.

Title: Raboisson P, et al. Discovery and characterization of AZD9272 and AZD6538-Two novel mGluR5 negative allosteric modulators selected for clinical development. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6974-9.

Quotation Request

Company Name:

Contact Person:

Email:

Quantity Required:

Country:

Additional Info:

SDS