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32887-03-9,MFCD01682071
Catalog No.:AA00C6GX

32887-03-9 | Pivmecillinam hydrochloride

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Purity
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Price(USD)
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1mg
98%
in stock  
$21.00   $15.00
- +
10mg
98%
in stock  
$65.00   $46.00
- +
25mg
98%
in stock  
$85.00   $60.00
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50mg
98%
in stock  
$115.00   $81.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C6GX
Chemical Name:
Pivmecillinam hydrochloride
CAS Number:
32887-03-9
Molecular Formula:
C21H34ClN3O5S
Molecular Weight:
476.0298
MDL Number:
MFCD01682071
SMILES:
O=C([C@@H]1N2C(=O)[C@H]([C@H]2SC1(C)C)/N=C/N1CCCCCC1)OCOC(=O)C(C)(C)C.Cl
Properties
Computed Properties
 
Complexity:
710  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
8  

Literature

Title: Efficacy of pivmecillinam for treatment of lower urinary tract infection caused by extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20120401

Title: French results of the ARESC study: clinical aspects and epidemiology of antimicrobial resistance in female patients with cystitis. Implications for empiric therapy.

Journal: Medecine et maladies infectieuses 20120201

Title: [Clinical efficacy of tebipenem pivoxil treatment in children with pneumonia, who had no relief despite having administered oral beta-lactam antibiotics].

Journal: The Japanese journal of antibiotics 20110601

Title: Inequality in quality? Regional and educational differences in treatment with fluoroquinolone in urinary tract infection of 236,376 Swedish patients.

Journal: BMJ quality & safety 20110101

Title: Characteristics of Escherichia coli causing persistence or relapse of urinary tract infections: phylogenetic groups, virulence factors and biofilm formation.

Journal: Virulence 20110101

Title: [Update on current care guidelines: urinary tract infections].

Journal: Duodecim; laaketieteellinen aikakauskirja 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Antibiotics for the treatment of dysentery in children.

Journal: International journal of epidemiology 20100401

Title: Pivmecillinam versus sulfamethizole for short-term treatment of uncomplicated acute cystitis in general practice: a randomized controlled trial.

Journal: Scandinavian journal of primary health care 20090101

Title: Risk of miscarriage for pregnant users of pivmecillinam: a population-based case-control study.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20080401

Title: Usefulness and problems of the urinary tract infection criteria for evaluating drug efficacy for complicated urinary tract infections.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20071001

Title: Clinical and bacteriological outcome of different doses and duration of pivmecillinam compared with placebo therapy of uncomplicated lower urinary tract infection in women: the LUTIW project.

Journal: Scandinavian journal of primary health care 20070101

Title: Successful treatment of ctx-m ESBL producing Escherichia coli relapsing pyelonephritis with long term pivmecillinam.

Journal: Scandinavian journal of infectious diseases 20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: New media for the semiselective isolation and enumeration of Xanthomonas campestris pv. mangiferaeindicae, the causal agent of mango bacterial black spot.

Journal: Journal of applied microbiology 20050101

Title: Hyperammonemic encephalopathy induced by a combination of valproate and pivmecillinam.

Journal: Acta neurologica Scandinavica 20040401

Title: The natural course of uncomplicated lower urinary tract infection in women illustrated by a randomized placebo controlled study.

Journal: Scandinavian journal of infectious diseases 20040101

Title: Pivmecillinam and adverse birth and neonatal outcomes: a population-based cohort study.

Journal: Scandinavian journal of infectious diseases 20040101

Title: [Is repeat antibiotic prescription following treatment with sulfonamide or pivmecillinam a valid method for assessment of therapeutic failure in urinary infection?].

Journal: Ugeskrift for laeger 20031103

Title: [Sulfamethizole versus pivmecillinam in urinary tract infections].

Journal: Ugeskrift for laeger 20031103

Title: Pivmecillinam--therapy of choice for lower urinary tract infection.

Journal: International journal of antimicrobial agents 20031001

Title: [Prescriptions of a new antibiotic following treatment with sulfamethizole or pivmecillinam].

Journal: Ugeskrift for laeger 20030922

Title: Symptomatic vaginal candidiasis after pivmecillinam and norfloxacin treatment of acute uncomplicated lower urinary tract infection.

Journal: International journal of antimicrobial agents 20021001

Title: Treatment failures after antibiotic therapy of uncomplicated urinary tract infections. A prescription database study.

Journal: Scandinavian journal of primary health care 20020601

Title: [Urinary antimicrobial prophylaxis].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20020501

Title: [Is new prescription of antibiotics after treatment with sulfonamide or pivmecillinam a validated method for assessment of treatment failure?].

Journal: Ugeskrift for laeger 20020211

Title: Three days of pivmecillinam or norfloxacin for treatment of acute uncomplicated urinary infection in women.

Journal: Scandinavian journal of infectious diseases 20020101

Title: [Repeat antibiotic prescriptions following treatment with sulfonamide or pivmecillinam. A survey of prescriptions among women aged 15-50 years in the county of Nordjylland].

Journal: Ugeskrift for laeger 20011231

Title: Hyperimmune bovine colostrum in the treatment of shigellosis in children: a double-blind, randomized, controlled trial.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20011201

Title: Effect of perorally administered pivmecillinam on the normal oropharyngeal, intestinal and skin microflora.

Journal: Journal of chemotherapy (Florence, Italy) 20010601

Title: Birth outcome and risk of neonatal hypoglycaemia following in utero exposure to pivmecillinam: a population-based cohort study with 414 exposed pregnancies.

Journal: Scandinavian journal of infectious diseases 20010101

Title: Pivmecillinam (selexid).

Journal: Drug and therapeutics bulletin 19781222

Title: Nicolle LE. Pivmecillinam in the treatment of urinary tract infections.J Antimicrob Chemother. 2000 Aug;46 Suppl A:35-39.

Title: Graninger W. Pivmecillinam--therapy of choice for lower urinary tract infection. Int J Antimicrob Agents. 2003 Oct;22 Suppl 2:73-8.

Title: Holme E, et al. Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. Lancet. 1989 Aug 26;2(8661):469-73.

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