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331947-66-1,MFCD09837707
Catalog No.:AA00C91J

331947-66-1 | (R)-(+)-Tolvaptan

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
3 weeks  
$466.00   $326.00
- +
2.5mg
3 weeks  
$688.00   $481.00
- +
25mg
3 weeks  
$4,213.00   $2,949.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C91J
Chemical Name:
(R)-(+)-Tolvaptan
CAS Number:
331947-66-1
Molecular Formula:
C26H25ClN2O3
Molecular Weight:
448.9413
MDL Number:
MFCD09837707
SMILES:
CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C
Properties
Computed Properties
 
Complexity:
674  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
4.8  

Literature

Title: Pharmacokinetics and pharmacodynamics of oral tolvaptan administered in 15- to 60-mg single doses to healthy Korean men.

Journal: Journal of cardiovascular pharmacology 20120401

Title: Tolvaptan for the treatment of heart failure: a review of the literature.

Journal: Expert opinion on pharmacotherapy 20110401

Title: Treatment of hypervolemic or euvolemic hyponatremia associated with heart failure, cirrhosis, or the syndrome of inappropriate antidiuretic hormone with tolvaptan: a clinical review.

Journal: Clinical therapeutics 20100601

Title: Pharmacology of new agents for acute heart failure syndromes.

Journal: The American journal of cardiology 20050919

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SDS
Tags:331947-66-1 Molecular Formula|331947-66-1 MDL|331947-66-1 SMILES|331947-66-1 (R)-(+)-Tolvaptan