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342577-38-2,MFCD11973642
Catalog No.:AA00C6HG

342577-38-2 | Velneperit

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$55.00   $38.00
- +
5mg
≥98%
in stock  
$135.00   $94.00
- +
10mg
≥98%
in stock  
$240.00   $168.00
- +
25mg
≥98%
in stock  
$530.00   $371.00
- +
50mg
98%
in stock  
$961.00   $673.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00C6HG
Chemical Name:
Velneperit
CAS Number:
342577-38-2
Molecular Formula:
C17H24F3N3O3S
Molecular Weight:
407.4510
MDL Number:
MFCD11973642
SMILES:
O=C([C@@H]1CC[C@H](CC1)NS(=O)(=O)C(C)(C)C)Nc1ccc(cn1)C(F)(F)F
Properties
Computed Properties
 
Complexity:
618  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
2.6  

Downstream Synthesis Route

[1]OrganicProcessResearchandDevelopment,2015,vol.19,p.531-536

Literature

Title: Identification of a novel and orally available benzimidazole derivative as an NPY Y5 receptor antagonist with in vivo efficacy.

Journal: Bioorganic & medicinal chemistry letters 20121101

Title: Discovery and evaluation of spirocyclic derivatives as antagonists of the neuropeptide Y5 receptor.

Journal: Bioorganic & medicinal chemistry letters 20120415

Title: Shinichi Oda*, et al. Development of an Optimized Synthetic and Purification Process of S-2367 (Velneperit), a Novel Neuropeptide Y (NPY) Y5 Receptor Antagonist. Org. Process Res. Dev., 2015, 19 (4), pp 531-536.

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Additional Info:
SDS
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