Home Other Building Blocks 342639-96-7
342639-96-7,MFCD30182306
Catalog No.:AA00CMW8

342639-96-7 | Kribb11

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥95%
in stock  
$89.00   $62.00
- +
10mg
≥95%
in stock  
$165.00   $115.00
- +
50mg
≥98%
in stock  
$693.00   $485.00
- +
100mg
≥98%
in stock  
$1,202.00   $842.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00CMW8
Chemical Name:
Kribb11
CAS Number:
342639-96-7
Molecular Formula:
C13H12N6O2
Molecular Weight:
284.2734
MDL Number:
MFCD30182306
SMILES:
CNc1ccc(c(n1)Nc1ccc2c(c1)cn[nH]2)[N+](=O)[O-]
Properties
Computed Properties
 
Complexity:
376  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
3.1  

Upstream Synthesis Route

[1]Patent:US6743795,2004,B1,.Locationinpatent:Page/Pagecolumn8

Literature

Title: Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20160301

Title: Solanesol protects human hepatic L02 cells from ethanol-induced oxidative injury via upregulation of HO-1 and Hsp70.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20150401

Title: Yoon YJ, et al. KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter. J Biol Chem. 2011 Jan 21;286(3):1737-47

Title: Samarasinghe B, et al. Heat shock factor 1 confers resistance to Hsp90 inhibitors through p62/SQSTM1 expression and promotion of autophagic flux. Biochem Pharmacol. 2014 Feb 1;87(3):445-55

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SDS
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