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3428-24-8,MFCD00463757
Catalog No.:AA003KET

3428-24-8 | 4,5-Dichlorocatechol

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1g
96%
in stock  
$261.00   $183.00
- +
5g
96%
in stock  
$760.00   $532.00
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10g
96%
in stock  
$1,258.00   $881.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003KET
Chemical Name:
4,5-Dichlorocatechol
CAS Number:
3428-24-8
Molecular Formula:
C6H4Cl2O2
Molecular Weight:
179.0008
MDL Number:
MFCD00463757
SMILES:
Oc1cc(Cl)c(cc1O)Cl
Properties
Properties
 
Form:
Solid  
MP:
111-114°C  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
106  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
XLogP3:
2.7  

Downstream Synthesis Route

[1]GazzettaChimicaItaliana,1898,vol.28I,p.222

3428-24-8    349-03-1   
7,8-dichloro-2-trifluoromethyldibenzo-p-dioxine 

[1]ChemistryofHeterocyclicCompounds,1994,vol.30,p.777-782    KhimiyaGeterotsiklicheskikhSoedinenii,1994,p.902-907

3428-24-8    400-70-4   
2-trifluoromethyl-3,7,8-trichlorodibenzo-p-dioxine 

[1]ChemistryofHeterocyclicCompounds,1994,vol.30,p.777-782    KhimiyaGeterotsiklicheskikhSoedinenii,1994,p.902-907

[1]Hu,Keke;Bunce,NigelJ.[JournalofBiochemicalandMolecularToxicology,1999,vol.13,#6,p.307-315]

[1]GazzettaChimicaItaliana,1898,vol.28I,p.222

Literature

Title: Characterization of the propanil biodegradation pathway in Sphingomonas sp. Y57 and cloning of the propanil hydrolase gene prpH.

Journal: Journal of hazardous materials 20111130

Title: 2,4,5-trichlororophenol and its derivatives induce biochemical and morphological changes in human peripheral blood lymphocytes in vitro.

Journal: Archives of environmental contamination and toxicology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Catechol 1,2-dioxygenase from the Gram-positive Rhodococcus opacus 1CP: quantitative structure/activity relationship and the crystal structures of native enzyme and catechols adducts.

Journal: Journal of structural biology 20100601

Title: Chlorophenols, chlorocatechols and chloroguaiacols induce DNA base oxidation in human lymphocytes (in vitro).

Journal: Toxicology 20100209

Title: Chlorophenols and chlorocatechols induce apoptosis in human lymphocytes (in vitro).

Journal: Toxicology letters 20091215

Title: Fine-tuning of catalytic properties of catechol 1,2-dioxygenase by active site tailoring.

Journal: Chembiochem : a European journal of chemical biology 20090417

Title: Characterization of catechol derivative removal by lignin peroxidase in aqueous mixture.

Journal: Bioresource technology 20090401

Title: Degradation of polychlorinated dibenzo-p-dioxins in aqueous solution by Fe(II)/H2O2/UV system.

Journal: Chemosphere 20060401

Title: Induction of cytotoxicity, aldehydic DNA lesions, and poly(ADP-ribose) polymerase-1 activation by catechol derivatives of pentachlorophenol in calf thymus DNA and in human breast cancer cells.

Journal: Chemical research in toxicology 20050201

Title: Chlorocatechols substituted at positions 4 and 5 are substrates of the broad-spectrum chlorocatechol 1,2-dioxygenase of Pseudomonas chlororaphis RW71.

Journal: Journal of bacteriology 20010201

Title: T Potrawfke , et al. Chlorocatechols Substituted at Positions 4 and 5 Are Substrates of the Broad-Spectrum Chlorocatechol 1,2-dioxygenase of Pseudomonas Chlororaphis RW71. J Bacteriol. 2001 Feb;183(3):997-1011.

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Tags:3428-24-8 Molecular Formula|3428-24-8 MDL|3428-24-8 SMILES|3428-24-8 4,5-Dichlorocatechol