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Home Other Building Blocks 3432-99-3
3432-99-3,MFCD19443704
Catalog No.:AA00C92P

3432-99-3 | 5,10-methylenetetrahydrofolate

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Purity
Availability
Price(USD)
Quantity
  
5mg
≥75% (mixture of diastereomers)
in stock  
$520.00   $364.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C92P
Chemical Name:
5,10-methylenetetrahydrofolate
CAS Number:
3432-99-3
Molecular Formula:
C20H23N7O6
Molecular Weight:
457.4399
MDL Number:
MFCD19443704
SMILES:
OC(=O)CC[C@@H](C(=O)O)NC(=O)c1ccc(cc1)N1CC2N(C1)c1c(NC2)[nH]c(=N)[nH]c1=O
Properties
Computed Properties
 
Complexity:
911  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-0.5  

Literature

Title: Renal failure after high-dose methotrexate in a child homozygous for MTHFR C677T polymorphism.

Journal: Pediatric blood & cancer 20080101

Title: Methylenetetrahydrofolate reductase gene polymorphisms: genomic predictors of clinical response to fluoropyrimidine-based chemotherapy?

Journal: Cancer chemotherapy and pharmacology 20060601

Title: The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites.

Journal: Molecular cancer therapeutics 20050501

Title: A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase.

Journal: Nature genetics 19950501

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SDS
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Tags:3432-99-3 Molecular Formula|3432-99-3 MDL|3432-99-3 SMILES|3432-99-3 5,10-methylenetetrahydrofolate