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34592-47-7,MFCD00005212
Catalog No.:AA003501

34592-47-7 | L-4-Thiazolidinecarboxylic acid

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10g
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25g
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100g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003501
Chemical Name:
L-4-Thiazolidinecarboxylic acid
CAS Number:
34592-47-7
Molecular Formula:
C4H7NO2S
Molecular Weight:
133.1689
MDL Number:
MFCD00005212
SMILES:
OC(=O)[C@@H]1CSCN1
Properties
Properties
 
BP:
350.3°C at 760 mmHg  
Form:
Solid  
MP:
190-200 °C (dec.);(lit.);  
Refractive Index:
-200 ° (C=1, 1mol/L NaOH)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
106  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-2.3  

Literature

Title: Role of thioproline on seed germination: interaction ROS-ABA and effects on antioxidative metabolism.

Journal: Plant physiology and biochemistry : PPB 20121001

Title: Photoelectron spectra of some antibiotic building blocks: 2-azetidinone and thiazolidine-carboxylic acid.

Journal: The journal of physical chemistry. A 20120823

Title: Enhancement of anthraquinone production in Morinda citrifolia cell suspension cultures after stimulation of the proline cycle with two proline analogs.

Journal: Biotechnology letters 20120301

Title: [Recent approaches of personalized medicine for inflammatory bowel disease].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20120301

Title: Design, synthesis and biological evaluation of 2-(substituted phenyl)thiazolidine-4-carboxylic acid derivatives as novel tyrosinase inhibitors.

Journal: Biochimie 20120201

Title: [The management of ulcerative colitis in remission stage and the strategies for colorectal cancer surveillance in ulcerative colitis].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20111201

Title: Simple derivatization of aldehydes with D-cysteine and their determination in beverages by liquid chromatography-tandem mass spectrometry.

Journal: Analytica chimica acta 20110930

Title: Rapid photoassisted access to N,O,S-polyheterocycles with benzoazocine and hydroquinoline cores: intramolecular cycloadditions of photogenerated azaxylylenes.

Journal: Angewandte Chemie (International ed. in English) 20110926

Title: Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides.

Journal: Amino acids 20110601

Title: Effect of radioprotective agents in sporulation medium on Bacillus subtilis spore resistance to hydrogen peroxide, wet heat and germicidal and environmentally relevant UV radiation.

Journal: Journal of applied microbiology 20110601

Title: Sulfur- and seleno-containing amino acids.

Journal: Amino acids 20110601

Title: Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors.

Journal: Bioorganic & medicinal chemistry 20110401

Title: Crystal structures of (2R,4R)-2-(polyhydroxyalkyl)-1,3-thiazolidine-4-carboxylic acids: condensation products of l-cysteine with d-hexoses.

Journal: Carbohydrate research 20110103

Title: Murine models of premature ageing for the study of diet-induced immune changes: improvement of leucocyte functions in two strains of old prematurely ageing mice by dietary supplementation with sulphur-containing antioxidants.

Journal: The Proceedings of the Nutrition Society 20101101

Title: Synthesis, structure and structure-activity relationship analysis of 3-tert-butoxycarbonyl-2-arylthiazolidine-4-carboxylic acid derivatives as potential antibacterial agents.

Journal: European journal of medicinal chemistry 20091001

Title: Purification, characterization and crystallization of pyrroline-5-carboxylate reductase from the hyperthermophilic archeon Sulfolobus Solfataricus.

Journal: Protein expression and purification 20090401

Title: Actions of a proline analogue, L-thiazolidine-4-carboxylic acid (T4C), on Trypanosoma cruzi.

Journal: PloS one 20090101

Title: Lithium thiazolidine-4-carboxylate: synthesis, spectroscopic characterization and preliminary in vitro cytotoxic studies in human HeLa cells.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201

Title: Ingestion of thioproline suppresses rat esophageal adenocarcinogenesis caused by duodenogastroesophageal reflux.

Journal: Oncology reports 20071201

Title: Identification of gene markers for formaldehyde exposure in humans.

Journal: Environmental health perspectives 20071001

Title: Determination of thiazolidine-4-carboxylates in urine by chloroformate derivatization and gas chromatography-electron impact mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20070901

Title: Dietary thioproline decreases spontaneous food intake and increases survival and neurological function in mice.

Journal: Antioxidants & redox signaling 20070101

Title: Conformational studies of proline-, thiaproline- and dimethylsilaproline-containing diketopiperazines.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20061001

Title: Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides.

Journal: Journal of medicinal chemistry 20060824

Title: An approach to the stereo-controlled synthesis of polycyclic derivatives of l-4-thiazolidinecarboxylic acid active against HIV-1 integrase.

Journal: European journal of medicinal chemistry 20060801

Title: Thioproline prevents carcinogenesis in the remnant stomach induced by duodenal reflux.

Journal: Cancer letters 20060618

Title: Successful computer guided planned synthesis of (4R)-thiazolidine carboxylic acid and its 2-substituted analogues as urease inhibitors.

Journal: Molecular diversity 20060501

Title: Impact of cis-proline analogs on peptide conformation.

Journal: Biopolymers 20060405

Title: A one-pot total synthesis of crambin.

Journal: Angewandte Chemie (International ed. in English) 20040503

Title: Thioproline inhibits development of esophageal adenocarcinoma induced by gastroduodenal reflux in rats.

Journal: Carcinogenesis 20040501

Title: Improvement of the macrophage functions in prematurely ageing mice by a diet supplemented with thiolic antioxidants.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20040101

Title: Expression of Sonic hedgehog-Fc fusion protein in Pichia pastoris. Identification and control of post-translational, chemical, and proteolytic modifications.

Journal: Protein expression and purification 20030601

Title: A diet supplemented with thiolic anti-oxidants improves leucocyte function in two strains of prematurely ageing mice.

Journal: Clinical and experimental pharmacology & physiology 20021101

Title: Novel dipeptide macrocycles from 4-oxo, -thio, and -amino-substituted proline derivatives.

Journal: The Journal of organic chemistry 20020531

Title: Retinoic acid exacerbates experimental radiation nephropathy.

Journal: Radiation research 20020201

Title: The amount of thiolic antioxidant ingestion needed to improve several immune functions is higher in aged than in adult mice.

Journal: Free radical research 20020201

Title: Oxidation of L-thiazolidine-4-carboxylate by delta1-pyrroline-5-carboxylate reductase in Escherichia coli.

Journal: Current microbiology 20010601

Title: Enhanced potency of human Sonic hedgehog by hydrophobic modification.

Journal: Biochemistry 20010410

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