Home Other Building Blocks 3562-63-8
3562-63-8,MFCD01939877
Catalog No.:AA00I6ZQ

3562-63-8 | (8R,9S,10R,13S,14S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%(HPLC)
in stock  
$120.00   $84.00
- +
5g
98%(HPLC)
in stock  
$335.00   $235.00
- +
10g
98%(HPLC)
in stock  
$540.00   $378.00
- +
25g
98%(HPLC)
in stock  
$1,124.00   $787.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I6ZQ
Chemical Name:
(8R,9S,10R,13S,14S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
CAS Number:
3562-63-8
Molecular Formula:
C22H30O3
Molecular Weight:
342.4718
MDL Number:
MFCD01939877
SMILES:
O=C1CC[C@]2(C(=C1)C(=C[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@]2(O)C(=O)C)C)C)C
Properties
Computed Properties
 
Complexity:
717  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2.6  

Literature

Title: Nomegestrol acetate sequentially or continuously combined to estradiol did not negatively affect membrane-receptor associated progestogenic effects in human breast cancer cells.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20121101

Title: Nomegestrol acetate/estradiol: in oral contraception.

Journal: Drugs 20121001

Title: Use of aromatase inhibitors as first- and second-line medical therapy in patients with endometrial adenocarcinoma: a retrospective study.

Journal: Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20120701

Title: Efficacy, safety, and tolerability of a monophasic oral contraceptive containing nomegestrol acetate and 17β-estradiol: a randomized controlled trial.

Journal: Obstetrics and gynecology 20120501

Title: The pharmacology of nomegestrol acetate.

Journal: Maturitas 20120401

Title: [Oral combined hormonal contraception containing nomegestrol acetate and 17beta-oestradiol--the statement of Polish Gynecological Society Experts Group].

Journal: Ginekologia polska 20120401

Title: Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011 (part 2).

Journal: Journal of cachexia, sarcopenia and muscle 20120301

Title: [Zoely, a combined oral contraceptive, monophasic pill containing estradiol and nomegestrol acetate].

Journal: Revue medicale de Liege 20120301

Title: Acupuncture as treatment of hot flashes and the possible role of calcitonin gene-related Peptide.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Cost-utility analysis of adjuvant goserelin (Zoladex) and adjuvant chemotherapy in premenopausal women with breast cancer.

Journal: BMC cancer 20120101

Title: Current approaches to the management of Her2-negative metastatic breast cancer.

Journal: Breast cancer research : BCR 20120101

Title: Sarcopenia: a major challenge in elderly patients with end-stage renal disease.

Journal: Journal of aging research 20120101

Title: Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol in comparison to one containing levonorgestrel and ethinylestradiol on markers of endocrine function.

Journal: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20111201

Title: Efficacy and tolerability of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol in a 24/4 regimen, in comparison to an oral contraceptive containing ethinylestradiol and drospirenone in a 21/7 regimen.

Journal: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20111201

Title: Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol compared with one containing levonorgestrel and ethinylestradiol on haemostasis, lipids and carbohydrate metabolism.

Journal: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20111201

Title: Uterine adenocarcinoma with feline leukemia virus infection.

Journal: Laboratory animal research 20111201

Title: Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011.

Journal: Journal of cachexia, sarcopenia and muscle 20111201

Title: Intracranial meningiomas in patients with uterine sarcoma treated with long-term megestrol acetate therapy.

Journal: World neurosurgery 20111101

Title: Randomised double-blind trial of megestrol acetate vs placebo in treatment-naive advanced hepatocellular carcinoma.

Journal: British journal of cancer 20110927

Title: Aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole and vorozole templates.

Journal: ChemMedChem 20110801

Title: Nomegestrol acetate: steroid receptor transactivation profile in Chinese hamster ovary cells and ovulation inhibition in rat and monkey.

Journal: Contraception 20110801

Title: [Analysis of the initial efficacy of nedaplatin combined with megestrol in concurrent chemoradiotherapy for advanced cervical cancer].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110801

Title: Nutritional approach to failure to thrive.

Journal: Korean journal of pediatrics 20110701

Title: Comparison of a 24-day and a 21-day pill regimen for the novel combined oral contraceptive, nomegestrol acetate and 17β-estradiol (NOMAC/E2): a double-blind, randomized study.

Journal: Human reproduction (Oxford, England) 20110601

Title: Antiemetic activity of megestrol acetate in patients receiving chemotherapy.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110501

Title: Nomegestrol acetate, a novel progestogen for oral contraception.

Journal: Steroids 20110501

Title: Inhibition of ovulation by NOMAC/E2, a novel monophasic oral contraceptive combining nomegestrol acetate and 17β-oestradiol: a double-blind, randomised, dose-finding pilot study.

Journal: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20110401

Title: Haemostatic effects of a new combined oral contraceptive, nomegestrol acetate/17β-estradiol, compared with those of levonorgestrel/ethinyl estradiol. A double-blind, randomised study.

Journal: Thrombosis and haemostasis 20110301

Title: Identification and validation of novel human pregnane X receptor activators among prescribed drugs via ligand-based virtual screening.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110201

Title: Multiple sclerosis and progestins: a comment to POPART'MUS.

Journal: Journal of the neurological sciences 20110115

Title: Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals.

Journal: BMC cancer 20110101

Title: An effective personalized approach to a rare tumor: prolonged survival in metastatic pancreatic acinar cell carcinoma based on genetic analysis and cell line development.

Journal: Journal of Cancer 20110101

Title: Cerebellar degeneration as presenting symptom of recurrent endometrial stromal sarcoma with sex-cord elements.

Journal: Case reports in neurology 20110101

Title: Paediatric palliative care: theory to practice.

Journal: Indian journal of palliative care 20110101

Title: HIV-Associated Venous Thromboembolism.

Journal: Mediterranean journal of hematology and infectious diseases 20110101

Title: State of the Art Review: Emerging Therapies: The Use of Insulin Sensitizers in the Treatment of Adolescents with Polycystic Ovary Syndrome (PCOS).

Journal: International journal of pediatric endocrinology 20110101

Title: Can electronic tools help improve nursing home quality?

Journal: ISRN nursing 20110101

Title: South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: The use of nomegestrol acetate in rapid preparation of endometrium before operative hysteroscopy in pre-menopausal women.

Journal: Steroids 20101201

Title: Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17 beta-oestradiol on ovarian function in comparison to a monophasic combined oral contraceptive containing drospirenone and ethinylestradiol.

Journal: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20101001

Title: Abstracts of the 5(th) Cachexia Conference, Barcelona, Spain, December 5-8, 2009.

Journal: Journal of cachexia, sarcopenia and muscle 20100901

Title: Regression of multiple intracranial meningiomas after cessation of long-term progesterone agonist therapy.

Journal: Journal of neurosurgery 20100501

Title: Sexual dysfunctions among people living with AIDS in Brazil.

Journal: Clinics (Sao Paulo, Brazil) 20100501

Title: Megestrol acetate versus metronomic cyclophosphamide in patients having exhausted all effective therapies under standard care.

Journal: British journal of cancer 20100413

Title: Randomised phase III clinical trial of 5 different arms of treatment on 332 patients with cancer cachexia.

Journal: European review for medical and pharmacological sciences 20100401

Title: Nomegestrol acetate: pharmacology, safety profile and therapeutic efficacy.

Journal: Drugs 20100326

Title: Conservative surgical management of stage IA endometrial carcinoma for fertility preservation.

Journal: Fertility and sterility 20100301

Title: Megestrol and embryonic extracts in the treatment of advanced hepatocellular carcinoma: A prospective randomized trial in the pre-sorafenib era.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20100201

Title: Management of hot flashes in women with breast cancer.

Journal: Current oncology (Toronto, Ont.) 20100201

Title: Megestrol acetate therapy for advanced low-grade endometrial stromal sarcoma.

Journal: Onkologie 20100101

Title: Recurrent endometrial stromal sarcoma: treatment with a progestin and gonadotropin releasing hormone agonist.

Journal: Sarcoma 20100101

Title: Update on options for treatment of metastatic castration-resistant prostate cancer.

Journal: OncoTargets and therapy 20100101

Title: Management of menopause-associated vasomotor symptoms: Current treatment options, challenges and future directions.

Journal: International journal of women's health 20100101

Title: [Treatment of uraemic anorexia with megestrol acetate].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101

Title: Management of dysfunctional uterine bleeding based on endometrial thickness.

Journal: International journal of women's health 20100101

Title: Hormonal therapy in advanced or recurrent endometrial cancer.

Journal: The Cochrane database of systematic reviews 20100101

Title: Optimal management of cancer anorexia-cachexia syndrome.

Journal: Cancer management and research 20100101

Title: Evaluation of degarelix in the management of prostate cancer.

Journal: Cancer management and research 20100101

Title: Radiotherapy combined with hormonal therapy in prostate cancer: the state of the art.

Journal: Cancer management and research 20100101

Title: Treatment of cachexia in oncology.

Journal: Indian journal of palliative care 20100101

Title: Pharmacoeconomic considerations in the treatment of breast cancer.

Journal: ClinicoEconomics and outcomes research : CEOR 20100101

Title: [Nomegestrol acetate: clinical pharmacology].

Journal: Minerva ginecologica 20091001

Title: Moving from tube to oral feeding in medically fragile nonverbal toddlers.

Journal: Journal of pediatric gastroenterology and nutrition 20090801

Title: Eleven years disease-free: role of chemotherapy in metastatic BRCA2-related breast cancer.

Journal: Nature reviews. Clinical oncology 20090801

Title: Certain progestins prevent the enhancing effect of 17beta-estradiol on NO-mediated inhibition of platelet aggregation by endothelial cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090401

Title: An open-label study of subdermal implants of estradiol-only versus subdermal implants of estradiol plus nomegestrol acetate: effects on symptom control, lipid profile and tolerability.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090401

Title: Bone mineral density in human immunodeficiency virus-1 infected men with hypogonadism prior to highly-active-antiretroviral-therapy (HAART).

Journal: European journal of medical research 20090101

Title: Amplitude-modulated electromagnetic fields for the treatment of cancer: discovery of tumor-specific frequencies and assessment of a novel therapeutic approach.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: Exemestane: a review of its use in postmenopausal women with breast cancer.

Journal: Drugs 20090101

Title: Adverse effects of androgen deprivation therapy in prostate cancer: Current management issues.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20090101

Title: Food effect on the bioavailability of two distinct formulations of megestrol acetate oral suspension.

Journal: International journal of nanomedicine 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Oxandrolone Improves Height Velocity and BMI in Patients with Cystic Fibrosis.

Journal: International journal of pediatric endocrinology 20090101

Title: Fatigue in cancer: a review of literature.

Journal: Indian journal of palliative care 20090101

Title: Aromatase inhibitor strategies in metastatic breast cancer.

Journal: International journal of women's health 20090101

Title: Economic evaluation of fulvestrant as an extra step in the treatment sequence for ER-positive advanced breast cancer.

Journal: British journal of cancer 20081209

Title: Absence of progesterone receptors in a failed case of fertility-sparing treatment in early endometrial cancer: a case report.

Journal: The Journal of reproductive medicine 20081101

Title: Insulin resistance in postmenopausal women: concurrent effects of hormone replacement therapy and coffee.

Journal: Climacteric : the journal of the International Menopause Society 20081001

Title: A randomized pilot study of atractylenolide I on gastric cancer cachexia patients.

Journal: Evidence-based complementary and alternative medicine : eCAM 20080901

Title: Nanocrystal technology, drug delivery and clinical applications.

Journal: International journal of nanomedicine 20080901

Title: Effects of nomegestrol acetate administration on central and peripheral beta-endorphin and allopregnanolone in ovx rats.

Journal: The Journal of steroid biochemistry and molecular biology 20080501

Title: Megestrol acetate-induced adrenal insufficiency.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20080401

Title: Is human hepatocellular carcinoma a hormone-responsive tumor?

Journal: World journal of gastroenterology 20080321

Title: Locally relapsed and metastatic uterine leiomyoma: a case report.

Journal: Journal of medical case reports 20080101

Title: Selective androgen receptor modulators in preclinical and clinical development.

Journal: Nuclear receptor signaling 20080101

Title: [Influence of dexamethasone on appetite and body weight in lung cancer patients].

Journal: Medicinski pregled 20080101

Title: Mammary fibroadenoma in a lamb.

Journal: Journal of veterinary science 20071201

Title: Management of arthralgias associated with aromatase inhibitor therapy.

Journal: Current oncology (Toronto, Ont.) 20071201

Title: Unusual causes of Cushing's syndrome.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20071101

Title: Letrozole in advanced breast cancer: the PO25 trial.

Journal: Breast cancer research and treatment 20071001

Title: The discovery and mechanism of action of letrozole.

Journal: Breast cancer research and treatment 20071001

Title: Letrozole in the extended adjuvant setting: MA.17.

Journal: Breast cancer research and treatment 20071001

Title: Safety of aromatase inhibitors in the adjuvant setting.

Journal: Breast cancer research and treatment 20071001

Title: The patient experience.

Journal: Breast cancer research and treatment 20071001

Title: Letter by Micheletti and Chevallier regarding article, 'Hormone therapy and venous thromboembolism among postmenopausal women: impact of the route of estrogen administration and progestogens: the ESTHER Study'.

Journal: Circulation 20070925

Title: Effect of estrogens on skin aging and the potential role of SERMs.

Journal: Clinical interventions in aging 20070901

Title: [Evaluation of the climacteric symptomatology modifications and clinical-instrumental parameters in women in physiological menopause treated with hormone replacement therapy with nomegestrol acetate and in surgical menopause treated with estrogen replacement therapy. Part I].

Journal: Minerva ginecologica 20070601

Title: [Evaluation of the hematochemical parameters and bone mineral density of women in physiological menopause treated with hormone replacement therapy with nomegestrol acetate and surgical menopause treated with estrogen replacement. Part II].

Journal: Minerva ginecologica 20070601

Title: The National Cancer Institute of Canada Clinical Trials Group MAP.3 trial: an international breast cancer prevention trial.

Journal: Current oncology (Toronto, Ont.) 20070601

Title: [Synthesis and spectral analysis of three kinds of epoxy pregnene derivatives].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20070501

Title: Frail older adults and palliative care.

Journal: JAMA 20070321

Title: Testosterone supplementation of megestrol therapy does not enhance lean tissue accrual in men with human immunodeficiency virus-associated weight loss: a randomized, double-blind, placebo-controlled, multicenter trial.

Journal: The Journal of clinical endocrinology and metabolism 20070201

Title: Longitudinal evaluation of serum leptin and bone mineral density in early postmenopausal women.

Journal: Menopause (New York, N.Y.) 20070101

Title: Systemic anticancer therapy in gynecological cancer patients with renal dysfunction.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20070101

Title: Neglected respiratory toxicity caused by cancer therapy.

Journal: The open respiratory medicine journal 20070101

Title: Effects of a single Silastic contraceptive implant containing nomegestrol acetate (Uniplant) on endometrial morphology and ovarian function for 1 year.

Journal: Contraception 20061201

Title: Megestrol acetate in cachexia and anorexia.

Journal: International journal of nanomedicine 20061201

Title: Hormonal treatment of human hepatocellular carcinoma.

Journal: Annals of the New York Academy of Sciences 20061101

Title: Activation of nitric oxide synthesis in human endothelial cells using nomegestrol acetate.

Journal: Obstetrics and gynecology 20061001

Title: Second- and third-generation aromatase inhibitors as first-line endocrine therapy in postmenopausal metastatic breast cancer patients: a pooled analysis of the randomised trials.

Journal: British journal of cancer 20060619

Title: Characterization of related impurities in megestrol acetate.

Journal: Journal of pharmaceutical and biomedical analysis 20060616

Title: A successful live birth through in vitro fertilization program after conservative treatment of FIGO grade I endometrial cancer.

Journal: Journal of Korean medical science 20060601

Title: [Pharmacological therapy of cancer anorexia-cachexia].

Journal: Nutricion hospitalaria 20060501

Title: Effects of estrogen, raloxifene, and hormone replacement therapy on serum C-reactive protein and homocysteine levels.

Journal: Maturitas 20060220

Title: Durable response of metastatic endometrial carcinoma to treatment with fulvestrant (Faslodex) after prior progestin and anastrozole therapy.

Journal: Gynecologic oncology 20060201

Title: Short-term progestin treatments prevent estrous induction by a GnRH agonist implant in anestrous bitches.

Journal: Theriogenology 20060120

Title: New progestagens for contraceptive use.

Journal: Human reproduction update 20060101

Title: Nanoparticles of poorly water-soluble drugs prepared by supercritical fluid extraction of emulsions.

Journal: Pharmaceutical research 20060101

Title: Orchiectomy or androgen receptor blockade attenuates baroreflex-mediated bradycardia in conscious rats.

Journal: BMC pharmacology 20060101

Title: Hepatocellular carcinoma--Pathological complete response to oral capecitabine, megestrol and thalidomide.

Journal: Acta oncologica (Stockholm, Sweden) 20060101

Title: Megestrol attenuates the hormonal response to CCK-4-induced panic attacks.

Journal: Depression and anxiety 20060101

Title: Cyclic progestin administration increases energy expenditure and decreases body fat mass in perimenopausal women.

Journal: Menopause (New York, N.Y.) 20060101

Title: Letrozole: a pharmacoeconomic review of its use in postmenopausal women with breast cancer.

Journal: PharmacoEconomics 20060101

Title: Review of cost-effectiveness analyses in hormonal therapies in advanced breast cancer.

Journal: Expert opinion on pharmacotherapy 20050901

Title: [Isolation and identification of two new epimer from the mother liquid of megestrol acetate].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050901

Title: Role of aromatase inhibitors in breast cancer.

Journal: British journal of cancer 20050801

Title: Bone loss and the aromatase inhibitors.

Journal: British journal of cancer 20050801

Title: The effects of aromatase inhibitors on lipids and thrombosis.

Journal: British journal of cancer 20050801

Title: Pregnancy following intracytoplasmic sperm injection and preimplantation genetic diagnosis after the conservative management of endometrial cancer.

Journal: Reproductive biomedicine online 20050601

Title: Nomegestrol acetate may enhance the skeletal effects of estradiol on biochemical markers of bone turnover in menopausal women after a 12-week treatment period.

Journal: Climacteric : the journal of the International Menopause Society 20050601

Title: Phase II study of sequential hormonal therapy with anastrozole/exemestane in advanced and metastatic breast cancer.

Journal: British journal of cancer 20050509

Title: Treatment with inhibitors of angiogenesis in advanced hepatocellular carcinoma: a new tool in our hands or simply a hope?

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050401

Title: Effects of the combined treatment with thalidomide, megestrol and interleukine-2 in cirrhotic patients with advanced hepatocellular carcinoma. A pilot study.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050401

Title: Retrospective review of megestrol use for weight loss in an elderly veteran population.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20050401

Title: Hormonal treatment of a recurrent granulosa cell tumor of the ovary: case report and review of the literature.

Journal: Gynecologic oncology 20050301

Title: Antigenotoxic effects of ascorbic acid against megestrol acetate-induced genotoxicity in mice.

Journal: Human & experimental toxicology 20050301

Title: [Actions of a 19-norprogesterone derivative on mammary gland: nomegestrol acetate].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20050201

Title: Effect of nomegestrol acetate on estrogen biosynthesis and transformation in MCF-7 and T47-D breast cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20050101

Title: The science of megestrol acetate delivery: potential to improve outcomes in cachexia.

Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20050101

Title: Clinical utility of serum HER2/neu in monitoring and prediction of progression-free survival in metastatic breast cancer patients treated with trastuzumab-based therapies.

Journal: Breast cancer research : BCR 20050101

Title: Control of sulfatase activity by nomegestrol acetate in normal and cancerous human breast tissues.

Journal: Anticancer research 20050101

Title: Progestogens: effects on clinical and biochemical parameters in postmenopausal women.

Journal: Menopause (New York, N.Y.) 20050101

Title: Bleeding patterns during continuous estradiol with different sequential progestogens therapy.

Journal: Menopause (New York, N.Y.) 20050101

Title: The role of aromatase inhibitors in ameliorating deleterious effects of ovarian stimulation on outcome of infertility treatment.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Benign metastasizing leiomyoma responsive to megestrol: case report and review of the literature.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101

Title: Osteoporosis associated with megestrol acetate.

Journal: Mayo Clinic proceedings 20041201

Title: Cost utility and budget impact of third-generation aromatase inhibitors for advanced breast cancer: a literature-based model analysis of costs in the Italian National Health Service.

Journal: Clinical therapeutics 20040901

Title: A comparison of the central effects of different progestins used in hormone replacement therapy.

Journal: Maturitas 20040820

Title: Therapy for unresectable hepatocellular carcinoma: review of the randomized clinical trials-II: systemic and local non-embolization-based therapies in unresectable and advanced hepatocellular carcinoma.

Journal: Anti-cancer drugs 20040601

Title: Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy?

Journal: British journal of cancer 20040504

Title: The role of MRI in the conservative management of endometrial cancer.

Journal: Gynecologic oncology 20040401

Title: Nomegestrol acetate: a progestin that deserves recognition.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040401

Title: Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy.

Journal: Breast cancer research : BCR 20040101

Title: [Nome gesrol (lutenyl) induced severe acute hepatitis].

Journal: Gastroenterologie clinique et biologique 20040101

Title: Serum leptin levels and body composition in postmenopausal women: effects of hormone therapy.

Journal: Menopause (New York, N.Y.) 20040101

Title: Acute effects of megestrol on the hypothalamic-pituitary-adrenal axis.

Journal: Cancer chemotherapy and pharmacology 20031201

Title: Economic evaluation of antiaromatase agents in the second-line treatment of metastatic breast cancer.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20031101

Title: An overview of nomegestrol acetate selective receptor binding and lack of estrogenic action on hormone-dependent cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20031101

Title: Effects of progestins of human proliferative endometrium: an in vitro model of potential clinical relevance.

Journal: International journal of molecular medicine 20031001

Title: Should aromatase inhibitors replace tamoxifen?

Journal: Drug and therapeutics bulletin 20030801

Title: Postmenopausal femur bone loss: effects of a low dose hormone replacement therapy.

Journal: Maturitas 20030725

Title: [Effects of a 19-norprogesterone derivative, the fourth decade nomegestrol acetate, on lipids].

Journal: Annales d'endocrinologie 20030601

Title: [Comparison of changes in biochemical markers of bone turnover after 6 months of hormone replacement therapy with either transdermal 17 beta-estradiol or equine conjugated estrogen plus nomegestrol acetate].

Journal: Gynecologie, obstetrique & fertilite 20030501

Title: Megestrol complications.

Journal: Chest 20030101

Title: [Antigonadotropic effects of a 19-nor-progesterone derivative: the example of nomegestrol acetate].

Journal: Gynecologie, obstetrique & fertilite 20030101

Title: Bone turnover markers and insulin-like growth factor components in metastatic breast cancer: results from a randomised trial of exemestane vs megestrol acetate.

Journal: Anticancer research 20030101

Title: Incidence of deep-venous thrombosis in nursing home residents using megestrol acetate.

Journal: Journal of the American Medical Directors Association 20030101

Title: Cancer cachexia.

Journal: Molecular cancer 20030101

Title: Effect of nomegestrol acetate on human estrogen sulfotransferase activity in the hormone-dependent MCF-7 and T-47D breast cancer cell lines.

Journal: Anticancer research 20030101

Title: Discovery of molecular mechanisms of neuroprotection using cell-based bioassays and oligonucleotide arrays.

Journal: Physiological genomics 20021029

Title: [Low-grade sarcoma of the endometrial stroma: late recurrence with ureteral and bladder involvement].

Journal: Archivos espanoles de urologia 20021001

Title: Phase I and pharmacokinetic study of vinblastine and high-dose megestrol acetate.

Journal: Cancer chemotherapy and pharmacology 20020901

Title: Variant estrogen receptors and their role in liver disease.

Journal: Molecular and cellular endocrinology 20020731

Title: Intramuscular depot medroxyprogesterone versus oral megestrol for the control of postmenopausal hot flashes in breast cancer patients: a randomized study.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20020601

Title: Effect of megestrol caproate on the reproductive function of laboratory animals.

Journal: Bulletin of experimental biology and medicine 20020601

Title: Fertility-preserving treatment in young patients with endometrial adenocarcinoma.

Journal: Cancer 20020415

Title: Effects of megestrol acetate on weight gain, body composition, and pulmonary function in patients with cystic fibrosis.

Journal: The Journal of pediatrics 20020401

Title: Existing and emerging endocrine therapies for breast cancer.

Journal: Cancer nursing 20020401

Title: Effects of transdermal hormone replacement therapy on levels of soluble P- and E-selectin in postmenopausal healthy women.

Journal: Fertility and sterility 20020301

Title: Approval summary: letrozole in the treatment of postmenopausal women with advanced breast cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020301

Title: [Reversal of nomegestrol acetate on multidrug resistance in drug-resistant human breast cancer cell line MCF7/ADR].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20020301

Title: Dronabinol versus megestrol acetate versus combination therapy for cancer-associated anorexia: a North Central Cancer Treatment Group study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020115

Title: Cost-effectiveness analysis of exemestane compared with megestrol in advanced breast cancer: a model for Europe and Australia.

Journal: PharmacoEconomics 20020101

Title: Tamoxifen resistant and refractory breast cancer: the value of aromatase inhibitors.

Journal: Drugs 20020101

Title: Estrogen as therapy for breast cancer.

Journal: Breast cancer research : BCR 20020101

Title: The impact of hormonal treatments on quality of life of patients with metastatic breast cancer.

Journal: Clinical therapeutics 20020101

Title: Efficacy and economics of hormonal therapies for advanced breast cancer.

Journal: Drugs & aging 20020101

Title: Implant contraception.

Journal: Seminars in reproductive medicine 20011201

Title: Serum immunoglobulins, total protein and albumin levels during UniplantR use by Nigerian women.

Journal: African journal of medicine and medical sciences 20011201

Title: Effects of different types of hormone replacement therapy on mammographic density.

Journal: Maturitas 20011130

Title: Megestrol treatment in patients with hepatocellular carcinoma.

Journal: British journal of cancer 20011101

Title: Megestrol-induced Cushing syndrome.

Journal: The Annals of pharmacotherapy 20011001

Title: Effects of a short-term suspension of hormone replacement therapy on mammographic density.

Journal: Fertility and sterility 20010901

Title: Management of common symptoms in terminally ill patients: Part I. Fatigue, anorexia, cachexia, nausea and vomiting.

Journal: American family physician 20010901

Title: Treatment. Court decision to allow marketing of generic form of weight-loss drug.

Journal: AIDS policy & law 20010803

Title: A comparison of megestrol acetate, nandrolone decanoate and dietary counselling for HIV associated weight loss.

Journal: International journal of andrology 20010801

Title: Carbohydrate metabolism in sickle cell patients using a subdermal implant containing nomegestrol acetate (Uniplant).

Journal: Contraception 20010501

Title: Hormonal therapy with megestrol in inoperable hepatocellular carcinoma characterized by variant oestrogen receptors.

Journal: British journal of cancer 20010401

Title: Cost-effectiveness analysis of exemestane compared with megestrol in patients with advanced breast carcinoma.

Journal: Cancer 20010201

Title: Megestrol and tamoxifen in patients with advanced endometrial cancer: an Eastern Cooperative Oncology Group Study (E4882).

Journal: American journal of clinical oncology 20010201

Title: Managing cancer-related anorexia/cachexia.

Journal: Drugs 20010101

Title: Contemporary drug therapy in palliative care: new directions.

Journal: Cancer investigation 20010101

Title: Reversal effects of nomegestrol acetate on multidrug resistance in adriamycin-resistant MCF7 breast cancer cell line.

Journal: Breast cancer research : BCR 20010101

Title: Prevention of menstruation with leuprorelin (GnRH agonist) in women undergoing myelosuppressive chemotherapy or radiochemotherapy for hematological malignancies: a pilot study.

Journal: Leukemia & lymphoma 20010101

Title: Inhibitory effect of nomegestrol acetate on steroidogenesis of cultured granulosa cells from rat ovary in vitro.

Journal: Acta pharmacologica Sinica 20010101

Title: Systemic treatment of hepatocellular carcinoma.

Journal: Digestive diseases (Basel, Switzerland) 20010101

Title: Progestogens and Cushing's syndrome.

Journal: Irish journal of medical science 19950101

Title: Comparison of diazepam with progestin for effectiveness in suppression of urine spraying behavior in cats.

Journal: Journal of the American Veterinary Medical Association 19920315

Title: Life-threatening hypercalcemia and tamoxifen.

Journal: The American journal of medicine 19900401

Title: Medical castration using megestrol acetate and minidose estrogen.

Journal: Urology 19880501

Title: Oral contraceptives and endometrial carcinoma: Case for progesterone-receptor defect.

Journal: Lancet (London, England) 19770312

Title: Multiple arterial occlusions and hypertension probably caused by an oral contraceptive: a patient in whom the development of renovascular hypertension has been followed.

Journal: Clinical nephrology 19761001

Title: Steroid contraceptives: neuro-psychiatric & electroencephalographic complications.

Journal: The Journal of international medical research 19730101

Title: Thromboembolic disease and the steroidal content of oral contraceptives. A report to the Committee on Safety of Drugs.

Journal: British medical journal 19700425

Title: Garcia JM, et al. Off-Label Megestrol in Patients with Anorexia-Cachexia Syndrome Associated with Malignancy and Its Treatments. Am J Med. 2018 Jun;131(6):623-629.e1.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:3562-63-8 Molecular Formula|3562-63-8 MDL|3562-63-8 SMILES|3562-63-8 (8R,9S,10R,13S,14S,17R)-17-Acetyl-17-hydroxy-6,10,13-trimethyl-8,9,10,11,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one