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357649-93-5,MFCD02307488
Catalog No.:AA00C9FS

357649-93-5 | Histone Acetyltransferase Inhibitor IV, CPTH2

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
100%
in stock  
$303.00   $212.00
- +
250mg
99+%
in stock  
$491.00   $344.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00C9FS
Chemical Name:
Histone Acetyltransferase Inhibitor IV, CPTH2
CAS Number:
357649-93-5
Molecular Formula:
C14H14ClN3S
Molecular Weight:
291.7991
MDL Number:
MFCD02307488
SMILES:
Clc1ccc(cc1)c1csc(n1)NN=C1CCCC1
Properties
Computed Properties
 
Complexity:
321  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.2  

Upstream Synthesis Route

[1]Patent:CN108409683,2018,A,.Locationinpatent:Paragraph0010;0011

[2]BioorganicandMedicinalChemistryLetters,2007,vol.17,#16,p.4635-4640

[3]BioorganicandMedicinalChemistry,2010,vol.18,#14,p.5063-5070

Literature

Title: Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.

Journal: Bioorganic & medicinal chemistry 20100715

Title: A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone.

Journal: Journal of medicinal chemistry 20090122

Title: Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp.

Journal: Bioorganic & medicinal chemistry letters 20070815

Quotation Request
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SDS
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Tags:357649-93-5 Molecular Formula|357649-93-5 MDL|357649-93-5 SMILES|357649-93-5 Histone Acetyltransferase Inhibitor IV, CPTH2
Catalog No.: AA00C9FS
357649-93-5,MFCD02307488
357649-93-5 | Histone Acetyltransferase Inhibitor IV, CPTH2
Pack Size： 10mg
Purity： 100%
in stock
$303.00 $212.00
Pack Size： 250mg
Purity： 99+%
in stock
$491.00 $344.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00C9FS
Chemical Name: Histone Acetyltransferase Inhibitor IV, CPTH2
CAS Number: 357649-93-5
Molecular Formula: C14H14ClN3S
Molecular Weight: 291.7991
MDL Number: MFCD02307488
SMILES: Clc1ccc(cc1)c1csc(n1)NN=C1CCCC1
Properties
Complexity: 321  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 19  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 3  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.2  
Upstream Synthesis Route
7283-39-8    536-38-9    357649-93-5 

[1]Patent:CN108409683,2018,A,.Locationinpatent:Paragraph0010;0011

[2]BioorganicandMedicinalChemistryLetters,2007,vol.17,#16,p.4635-4640

[3]BioorganicandMedicinalChemistry,2010,vol.18,#14,p.5063-5070

Literature fold

Title: Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.

Journal: Bioorganic & medicinal chemistry20100715

Title: A novel histone acetyltransferase inhibitor modulating Gcn5 network: cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone.

Journal: Journal of medicinal chemistry20090122

Title: Synthesis and in vitro activity of 2-thiazolylhydrazone derivatives compared with the activity of clotrimazole against clinical isolates of Candida spp.

Journal: Bioorganic & medicinal chemistry letters20070815

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