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35838-58-5,MFCD00209848
Catalog No.:AA007E9N

35838-58-5 | 1H-Pyrazolo[3,4-b]pyridine-5-carboxylicacid, 1-ethyl-4-[2-(1-methylethylidene)hydrazinyl]-, ethyl ester, hydrochloride(1:1)

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Purity
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Quantity
  
10mg
≥98%(HPLC)
in stock  
$256.00   $179.00
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50mg
≥98%(HPLC)
in stock  
$879.00   $615.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA007E9N
Chemical Name:
1H-Pyrazolo[3,4-b]pyridine-5-carboxylicacid, 1-ethyl-4-[2-(1-methylethylidene)hydrazinyl]-, ethyl ester, hydrochloride(1:1)
CAS Number:
35838-58-5
Molecular Formula:
C14H19N5O2
Molecular Weight:
289.3330
MDL Number:
MFCD00209848
SMILES:
CCOC(=O)c1cnc2c(c1NN=C(C)C)cnn2CC
NSC Number:
163611
Properties
Computed Properties
 
Complexity:
397  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  

Literature

Title: Antidepressant-like effect of etazolate, a cyclic nucleotide phosphodiesterase 4 inhibitor--an approach using rodent behavioral antidepressant tests battery.

Journal: European journal of pharmacology 20120815

Title: EHT0202 in Alzheimer's disease: a 3-month, randomized, placebo-controlled, double-blind study.

Journal: Current Alzheimer research 20110301

Title: Etazolate improves performance in a foraging and homing task in aged rats.

Journal: European journal of pharmacology 20100525

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Etazolate, a neuroprotective drug linking GABA(A) receptor pharmacology to amyloid precursor protein processing.

Journal: Journal of neurochemistry 20080701

Title: TcPDE4, a novel membrane-associated cAMP-specific phosphodiesterase from Trypanosoma cruzi.

Journal: Molecular and biochemical parasitology 20060101

Title: Expression, purification, and characterization of human cAMP-specific phosphodiesterase (PDE4) subtypes A, B, C, and D.

Journal: Biochemical and biophysical research communications 19970519

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Tags:35838-58-5 Molecular Formula|35838-58-5 MDL|35838-58-5 SMILES|35838-58-5 1H-Pyrazolo[3,4-b]pyridine-5-carboxylicacid, 1-ethyl-4-[2-(1-methylethylidene)hydrazinyl]-, ethyl ester, hydrochloride(1:1)