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364-98-7,MFCD00078578
Catalog No.:AA0039B6

364-98-7 | diazoxide

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25mg
95%
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$6.00   $4.00
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250mg
95%
in stock  
$17.00   $12.00
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1g
95%
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$65.00   $46.00
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5g
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$164.00   $115.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0039B6
Chemical Name:
diazoxide
CAS Number:
364-98-7
Molecular Formula:
C8H7ClN2O2S
Molecular Weight:
230.6714
MDL Number:
MFCD00078578
SMILES:
Clc1ccc2c(c1)S(=O)(=O)NC(=N2)C
Properties
Computed Properties
 
Complexity:
360  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
XLogP3:
1.2  

Upstream Synthesis Route

[1]Patent:CN106831648,2017,A,.Locationinpatent:Paragraph0036;0037;0038;0039;0040

[1]Patent:CN106831648,2017,A,.Locationinpatent:Paragraph0029;0030

[1]Patent:CN106831648,2017,A,.Locationinpatent:Paragraph0031;0032

Downstream Synthesis Route

[1]TOPLISS;SHERLOCK;REIMANN;KONZELMAN;SHAPIRO;PETTERSEN;SCHNEIDER;SPERBER[Journalofmedicinalchemistry,1963,vol.6,p.122-127]

123-41-1    364-98-7   
CASUnavailable 

[1]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2013/130411,2013,A1Locationinpatent:Paragraph00658

[2]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn122-124

[3]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn123

[4]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn119-122

[5]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn124

[6]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn119-122

[7]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn119-120

[8]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn119-122

[9]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn118-119;121

[10]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn118-119;121

[11]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn118-119

[12]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn117-118

[13]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-WO2007/81521,2007,A2Locationinpatent:Page/Pagecolumn137

[1]CurrentPatentAssignee:OPTASIAHEALTHCARELIMITED-US2006/51418,2006,A1Locationinpatent:Page/Pagecolumn27

Literature

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Journal: The Journal of biological chemistry 20171020

Title: Diazoxide prevents reactive oxygen species and mitochondrial damage, leading to anti-hypertrophic effects.

Journal: Chemico-biological interactions 20170105

Title: Mitochondrial Channel Opener Diazoxide Attenuates Hypoxia-Induced sFlt-1 Release in Human Choriocarcinoma Cells.

Journal: Journal of menopausal medicine 20140401

Title: Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats.

Journal: Toxicology and applied pharmacology 20130201

Title: Expression and regulation of nampt in human islets.

Journal: PloS one 20130101

Title: Skeletal muscle post-conditioning by diazoxide, anti-oxidative and anti-apoptotic mechanisms.

Journal: Molecular biology reports 20121201

Title: Mechanisms of antihyperglycaemic action of efaroxan in mice: time for reappraisal of α2A-adrenergic antagonism in the treatment of type 2 diabetes?

Journal: Diabetologia 20121101

Title: Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1.

Journal: Journal of molecular and cellular cardiology 20121101

Title: Octreotide for the treatment of sulfonylurea poisoning.

Journal: Clinical toxicology (Philadelphia, Pa.) 20121101

Title: Late anti-apoptotic effect of K(ATP) channel opening in skeletal muscle.

Journal: Clinical and experimental pharmacology & physiology 20121101

Title: Agelaia MP-I: a peptide isolated from the venom of the social wasp, Agelaia pallipes pallipes, enhances insulin secretion in mice pancreatic islets.

Journal: Toxicon : official journal of the International Society on Toxinology 20120915

Title: Prostatic relaxation induced by agmatine is decreased in spontaneously hypertensive rats.

Journal: BJU international 20120901

Title: Effects of Aβ1‐42 on the current of KATP channels in cultured cholinergic neurons.

Journal: Neurological research 20120901

Title: Mitochondrial ROMK channel is a molecular component of mitoK(ATP).

Journal: Circulation research 20120803

Title: Synthesis and pharmacological activity of N-(2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl)-4H-1,2,4-benzothiadiazine-3-carboxamides 1,1-dioxides on rat uterus, rat aorta and rat pancreatic β-cells.

Journal: European journal of medicinal chemistry 20120801

Title: Intractable absence seizures in hyperinsulinism-hyperammonemia syndrome.

Journal: Pediatric neurology 20120801

Title: Effects of mitochondrial ATP-sensitive K(+) channel on protein kinase C pathway and airway smooth muscle cell proliferation in asthma.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120801

Title: Nuciferine stimulates insulin secretion from beta cells-an in vitro comparison with glibenclamide.

Journal: Journal of ethnopharmacology 20120713

Title: Successful control of intractable hypoglycemia using radiopharmaceutical therapy with strontium-89 in a case with malignant insulinoma and bone metastases.

Journal: Japanese journal of clinical oncology 20120701

Title: Mitochondrial K+ channels are involved in ischemic postconditioning in rat hearts.

Journal: The journal of physiological sciences : JPS 20120701

Title: Enhancement of liver regeneration by adenosine triphosphate-sensitive K⁺ channel opener (diazoxide) after partial hepatectomy.

Journal: Transplantation 20120615

Title: The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine.

Journal: The Journal of physiology 20120615

Title: Role of connexin-43 in protective PI3K-Akt-GSK-3β signaling in cardiomyocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20120615

Title: Nutrient detection by incretin hormone secreting cells.

Journal: Physiology & behavior 20120606

Title: Diazoxide inhibits aortic endothelial cell apoptosis in diabetic rats via activation of ERK.

Journal: Acta diabetologica 20120601

Title: Quantitative pancreatic β cell MRI using manganese-enhanced Look-Locker imaging and two-site water exchange analysis.

Journal: Magnetic resonance in medicine 20120601

Title: Protective effects of diazoxide against Aβ₂₅₋₃₅-induced PC12 cell apoptosis due to prevention of endoplasmic reticulum stress.

Journal: Neuroreport 20120530

Title: Two neonatal diabetes mutations on transmembrane helix 15 of SUR1 increase affinity for ATP and ADP at nucleotide binding domain 2.

Journal: The Journal of biological chemistry 20120525

Title: Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells.

Journal: American journal of physiology. Endocrinology and metabolism 20120515

Title: Partial ABCC8 gene deletion mutations causing diazoxide-unresponsive hyperinsulinaemic hypoglycaemia.

Journal: Pediatric diabetes 20120501

Title: Protective effect of delayed remote limb ischemic postconditioning: role of mitochondrial K(ATP) channels in a rat model of focal cerebral ischemic reperfusion injury.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120501

Title: Polysaccharide isolated from Triticum aestivum stimulates insulin release from pancreatic cells via the ATP-sensitive K+ channel.

Journal: International journal of molecular medicine 20120501

Title: Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass: the pathophysiological role of GLP1 and its response to a somatostatin analogue.

Journal: European journal of endocrinology 20120501

Title: A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function.

Journal: Biochemical and biophysical research communications 20120427

Title: Diazoxide attenuates ischemia/reperfusion injury via upregulation of heme oxygenase-1 after liver transplantation in rats.

Journal: World journal of gastroenterology 20120421

Title: Mice expressing a human K(ATP) channel mutation have altered channel ATP sensitivity but no cardiac abnormalities.

Journal: Diabetologia 20120401

Title: Diazoxide pretreatment enhances L6 skeletal myoblast survival and inhibits apoptosis induced by hydrogen peroxide.

Journal: Anatomical record (Hoboken, N.J. : 2007) 20120401

Title: Anesthetic management of a 6 month-old infant for near total pancreatectomy with persistent hyperinsulinemic hypoglycemia.

Journal: Korean journal of anesthesiology 20120401

Title: Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell.

Journal: Molecular and cellular endocrinology 20120305

Title: Role of the amino-terminal transmembrane domain of sulfonylurea receptor SUR2B for coupling to K(IR)6.2, ligand binding, and oligomerization.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120301

Title: Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.

Journal: American journal of physiology. Endocrinology and metabolism 20120301

Title: Regulation of calcium in pancreatic α- and β-cells in health and disease.

Journal: Cell calcium 20120301

Title: Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells.

Journal: Diabetes 20120301

Title: Ethanol causes endoplasmic reticulum stress and impairment of insulin secretion in pancreatic β-cells.

Journal: Alcohol (Fayetteville, N.Y.) 20120201

Title: Successful treatment of congenital hyperinsulinism with long-acting release octreotide.

Journal: European journal of endocrinology 20120201

Title: Disruption and stabilization of β-cell actin microfilaments differently influence insulin secretion triggered by intracellular Ca2+ mobilization or store-operated Ca2+ entry.

Journal: FEBS letters 20120102

Title: Mitochondrial calcium homeostasis as potential target for mitochondrial medicine.

Journal: Mitochondrion 20120101

Title: The heterogeneity of focal forms of congenital hyperinsulinism.

Journal: The Journal of clinical endocrinology and metabolism 20120101

Title: Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs).

Journal: Gut 20120101

Title: US-guided ethanol ablation of insulinomas: a new treatment option.

Journal: Gastrointestinal endoscopy 20120101

Title: Non-classic androgen actions in Sertoli cell membrane in whole seminiferous tubules: effects of nandrolone decanoate and catechin.

Journal: Steroids 20120101

Title: K(ATP) channel openers in the trigeminovascular system.

Journal: Cephalalgia : an international journal of headache 20120101

Title: Activation of IL-11/STAT3 pathway in preconditioned human skeletal myoblasts blocks apoptotic cascade under oxidant stress.

Journal: Regenerative medicine 20120101

Title: Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells.

Journal: PloS one 20120101

Title: Hyperglycemia raises the threshold of levosimendan- but not milrinone-induced postconditioning in rat hearts.

Journal: Cardiovascular diabetology 20120101

Title: Increase of ATP-sensitive potassium (K(ATP)) channels in the heart of type-1 diabetic rats.

Journal: Cardiovascular diabetology 20120101

Title: Acute and chronic animal models for the evaluation of anti-diabetic agents.

Journal: Cardiovascular diabetology 20120101

Title: Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol.

Journal: PloS one 20120101

Title: Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor β.

Journal: PloS one 20120101

Title: High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels.

Journal: Cardiovascular diabetology 20120101

Title: The diabetic heart: too sweet for its own good?

Journal: Cardiology research and practice 20120101

Title: Effects of Extract from Solid-State Fermented Cordyceps sinensis on Type 2 Diabetes Mellitus.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension.

Journal: PloS one 20120101

Title: Insulinotropic effect of the non-steroidal compound STX in pancreatic β-cells.

Journal: PloS one 20120101

Title: Metoclopramide-induced oculogyric crisis presenting as encephalitis in a young girl.

Journal: Indian journal of pharmacology 20120101

Title: Hyperinsulinism presenting in childhood and treatment by conservative pancreatectomy.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20120101

Title: [Effects of diazoxide on the mitochondrial membrane potential and ROS generation in rat uterus cells].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20120101

Title: Localized acquired hypertrichosis associated with the application of a splint.

Journal: Case reports in pediatrics 20120101

Title: Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats.

Journal: TheScientificWorldJournal 20120101

Title: Bariatric surgery in hypothalamic obesity.

Journal: Frontiers in endocrinology 20120101

Title: Insulinoma and anaesthetic implications.

Journal: Indian journal of anaesthesia 20120101

Title: Towards therapeutic applications of arthropod venom k(+)-channel blockers in CNS neurologic diseases involving memory acquisition and storage.

Journal: Journal of toxicology 20120101

Title: Ficus deltoidea: A Potential Alternative Medicine for Diabetes Mellitus.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells.

Journal: PloS one 20120101

Title: Primary aldosteronism in pregnancy.

Journal: Acta clinica Belgica 20120101

Title: Echocardiography monitoring for diazoxide induced pericardial effusion.

Journal: BMJ case reports 20120101

Title: Drug-induced hepatitis following use of octreotide for long-term treatment of congenital hyperinsulinism.

Journal: BMJ case reports 20120101

Title: Paclitaxel-induced endothelial dysfunction in living rats is prevented by nicorandil via reduction of oxidative stress.

Journal: Journal of pharmacological sciences 20120101

Title: Seizure due to somatostatin analog discontinuation in a case diagnosed as congenital hyperinsulinism novel mutation.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20120101

Title: [Neuroprotective effect of ischemic postconditioning and remote preconditioning. Prospective of clinical use].

Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20120101

Title: Cardiac subsarcolemmal and interfibrillar mitochondria display distinct responsiveness to protection by diazoxide.

Journal: PloS one 20120101

Title: The effect of tempol administration on the aortic contractile responses in rat preeclampsia model.

Journal: ISRN pharmacology 20120101

Title: Aquaporin-7 expression during coronary artery bypass grafting with diazoxide.

Journal: Scandinavian cardiovascular journal : SCJ 20111201

Title: Protective effect of diazoxide against antimycin A-induced mitochondrial dysfunction in osteoblastic MC3T3-E1 cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111201

Title: Inhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilon.

Journal: Biochimica et biophysica acta 20111201

Title: Rapid functional evaluation of beta-cells by extracellular recording of membrane potential oscillations with microelectrode arrays.

Journal: Pflugers Archiv : European journal of physiology 20111201

Title: Morphological mosaicism of the pancreatic islets: a novel anatomopathological form of persistent hyperinsulinemic hypoglycemia of infancy.

Journal: The Journal of clinical endocrinology and metabolism 20111201

Title: Potential candidate genomic biomarkers of drug induced vascular injury in the rat.

Journal: Toxicology and applied pharmacology 20111201

Title: Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system.

Journal: Circulation. Arrhythmia and electrophysiology 20111201

Title: Activation of K(ATP) channels suppresses glucose production in humans.

Journal: The Journal of clinical investigation 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death.

Journal: Pharmaceutical research 20111101

Title: Improved control of severe hypoglycemia in patients with malignant insulinomas by peptide receptor radionuclide therapy.

Journal: The Journal of clinical endocrinology and metabolism 20111101

Title: Rapid signaling responses in Sertoli cell membranes induced by follicle stimulating hormone and testosterone: calcium inflow and electrophysiological changes.

Journal: Life sciences 20111010

Title: Lessons in human biology from a monogenic pancreatic β cell disease.

Journal: The Journal of clinical investigation 20111003

Title: In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions.

Journal: The Journal of clinical investigation 20111003

Title: Treatment with somatostatin analogs and chemoembolization of liver metastases for severe hypoglycemia in malignant insulinomas.

Journal: Journal of endocrinological investigation 20111001

Title: Advances in the etiology and management of hyperinsulinemic hypoglycemia after Roux-en-Y gastric bypass.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20111001

Title: Hyperinsulinaemic hypoglycaemia and diabetes mellitus due to dominant ABCC8/KCNJ11 mutations.

Journal: Diabetologia 20111001

Title: Mechanisms involved in the desflurane-induced post-conditioning of isolated human right atria from patients with type 2 diabetes.

Journal: British journal of anaesthesia 20111001

Title: Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3.

Journal: Diabetes 20111001

Title: Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.

Journal: PLoS genetics 20111001

Title: Mechanisms of p-methoxycinnamic acid-induced increase in insulin secretion.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20111001

Title: Genome protective effect of metformin as revealed by reduced level of constitutive DNA damage signaling.

Journal: Aging 20111001

Title: Isoflurane decreases death of human embryonic stem cell-derived, transcriptional marker Nkx2.5(+) cardiac progenitor cells.

Journal: Acta anaesthesiologica Scandinavica 20111001

Title: Glitazone-like action of glimepiride and glibenclamide in primary human adipocytes.

Journal: Diabetes, obesity & metabolism 20110901

Title: Subsecond regulation of striatal dopamine release by pre-synaptic KATP channels.

Journal: Journal of neurochemistry 20110901

Title: Diazoxide decreases ischemia-reperfusion injury in a rat model of lung transplantation.

Journal: Transplantation proceedings 20110901

Title: Characterization of an ATP-sensitive K(+) channel in rat carotid body glomus cells.

Journal: Respiratory physiology & neurobiology 20110815

Title: Diazoxide suppresses hepatic ischemia/reperfusion injury after mouse liver transplantation by a BCL-2-dependent mechanism.

Journal: The Journal of surgical research 20110801

Title: Interaction of morphine and potassium channel openers on experimental models of pain in mice.

Journal: Fundamental & clinical pharmacology 20110801

Title: Current and future drug targets in weight management.

Journal: Pharmaceutical research 20110801

Title: Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts.

Journal: Journal of molecular and cellular cardiology 20110801

Title: Heat shock protein 90 mediates anti-apoptotic effect of diazoxide by preventing the cleavage of Bid in hypothermic preservation rat hearts.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110801

Title: Severity of diabetes governs vascular lipoprotein lipase by affecting enzyme dimerization and disassembly.

Journal: Diabetes 20110801

Title: Treatment of congenital hyperinsulinism with lanreotide acetate (Somatuline Autogel).

Journal: The Journal of clinical endocrinology and metabolism 20110801

Title: ATP-sensitive potassium (KATP) channel activation decreases intraocular pressure in the anterior chamber of the eye.

Journal: Investigative ophthalmology & visual science 20110801

Title: [The effect of 5-HD on expression of PKC-alpha in rats of chronic hypoxic pulmonary hypertension].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110801

Title: The effect of adrenergic β(2) receptor agonist on paraplegia following clamping of abdominal aorta.

Journal: Archives of medical science : AMS 20110801

Title: Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells.

Journal: The Journal of biological chemistry 20110722

Title: Type-specific human papillomavirus detection in cervical smears in Romania.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20110701

Title: Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets.

Journal: Diabetologia 20110701

Title: Ontogeny of sulfonylurea-binding regulatory subunits of K(ATP) channels in the pregnant rat myometrium.

Journal: Reproduction (Cambridge, England) 20110701

Title: Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process.

Journal: Bioorganic & medicinal chemistry 20110701

Title: Glucosensing in parvocellular neurons of the rat hypothalamic paraventricular nucleus.

Journal: The European journal of neuroscience 20110701

Title: Dominantly acting ABCC8 mutations in patients with medically unresponsive hyperinsulinaemic hypoglycaemia.

Journal: Clinical genetics 20110601

Title: The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia.

Journal: The Biochemical journal 20110601

Title: Characterization of ABCC8 and KCNJ11 gene mutations and phenotypes in Korean patients with congenital hyperinsulinism.

Journal: European journal of endocrinology 20110601

Title: Mitochondrial KATP channels participate in the limitation of infarct size by cariporide.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110601

Title: Diazoxide-unresponsive congenital hyperinsulinism in children with dominant mutations of the β-cell sulfonylurea receptor SUR1.

Journal: Diabetes 20110601

Title: Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats.

Journal: Anesthesia and analgesia 20110601

Title: Mutations of the same conserved glutamate residue in NBD2 of the sulfonylurea receptor 1 subunit of the KATP channel can result in either hyperinsulinism or neonatal diabetes.

Journal: Diabetes 20110601

Title: [Protective effects of mitochondrial ATP-sensitive potassium channel on A549 cell apoptosis induced by hyperoxia].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110601

Title: Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat.

Journal: Neuroscience letters 20110516

Title: Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels.

Journal: Journal of medicinal chemistry 20110512

Title: Hypertensive emergencies in children.

Journal: Indian journal of pediatrics 20110501

Title: Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501

Title: The vasorelaxant effect of hydrogen sulfide is enhanced in streptozotocin-induced diabetic rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110501

Title: Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain condition.

Journal: Neuroscience 20110428

Title: Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).

Journal: The Journal of biological chemistry 20110415

Title: Role of PI3K/Akt in diazoxide preconditioning against rat hippocampal neuronal death in pilocarpine-induced seizures.

Journal: Brain research 20110406

Title: GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways.

Journal: Cardiovascular research 20110401

Title: Treat the graft to improve the regenerative ability of the host.

Journal: Medical hypotheses 20110401

Title: Glucose-dependent changes in SNARE protein levels in pancreatic β-cells.

Journal: Endocrinology 20110401

Title: Partial inhibition of insulin secretion results in glucose intolerance but not hyperglucagonemia.

Journal: Diabetes 20110401

Title: In vitro recovery of ATP-sensitive potassium channels in β-cells from patients with congenital hyperinsulinism of infancy.

Journal: Diabetes 20110401

Title: Congenital hyperinsulinism: review of 12 Tunisian cases.

Journal: La Tunisie medicale 20110401

Title: Transient neonatal hyperinsulinemic hypoglycemia and neurological outcome: a case report.

Journal: Minerva pediatrica 20110401

Title: KCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia.

Journal: Cell death & disease 20110401

Title: Pancreatic endocrine tumors.

Journal: North American journal of medical sciences 20110401

Title: The protective roles of mitochondrial ATP-sensitive potassium channels during hypoxia-ischemia-reperfusion in brain.

Journal: Neuroscience letters 20110310

Title: Functional role of the activity of ATP-sensitive potassium channels in electrical behavior of hippocampal neurons: experimental and theoretical studies.

Journal: Journal of theoretical biology 20110307

Title: [Malignant insulinoma].

Journal: Orvosi hetilap 20110306

Title: Hyperinsulinemic hypoglycemia associated with ectopic Cushing's syndrome due to a pancreatic endocrine tumor in a Type 2 diabetes mellitus patient: clinical implications of a rare association.

Journal: Journal of endocrinological investigation 20110301

Title: Inhibition of gastric motility by hyperglycemia is mediated by nodose ganglia KATP channels.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20110301

Title: Genome-wide homozygosity analysis reveals HADH mutations as a common cause of diazoxide-responsive hyperinsulinemic-hypoglycemia in consanguineous pedigrees.

Journal: The Journal of clinical endocrinology and metabolism 20110301

Title: Synthesis and biological evaluation of 5-membered spiro heterocycle-benzopyran derivatives against myocardial ischemia.

Journal: European journal of medicinal chemistry 20110301

Title: Postconditioning in focal cerebral ischemia: role of the mitochondrial ATP-dependent potassium channel.

Journal: Brain research 20110223

Title: Induction of insulin secretion by an aqueous extract of Tabernanhte iboga Baill. (Apocynaceae) in rat pancreatic islets of Langerhans.

Journal: Journal of ethnopharmacology 20110216

Title: Interactive medical case. Lying low.

Journal: The New England journal of medicine 20110210

Title: Recognition of sulfonylurea receptor (ABCC8/9) ligands by the multidrug resistance transporter P-glycoprotein (ABCB1): functional similarities based on common structural features between two multispecific ABC proteins.

Journal: The Journal of biological chemistry 20110204

Title: Levosimendan modulates programmed forms of cell death through K(ATP) channels and nitric oxide.

Journal: Journal of cardiovascular pharmacology 20110201

Title: Genetics of congenital hyperinsulinemic hypoglycemia.

Journal: Seminars in pediatric surgery 20110201

Title: KATP channel mutations in congenital hyperinsulinism.

Journal: Seminars in pediatric surgery 20110201

Title: A specialized team approach to diagnosis and medical versus surgical treatment of infants with congenital hyperinsulinism.

Journal: Seminars in pediatric surgery 20110201

Title: Rare forms of congenital hyperinsulinism.

Journal: Seminars in pediatric surgery 20110201

Title: Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic Ca2+ and cAMP.

Journal: Endocrinology 20110201

Title: Role of vascular K(ATP) channels in blood pressure variability after sinoaortic denervation in rats.

Journal: Acta pharmacologica Sinica 20110201

Title: Effect of glibenclamide on antinociceptive effects of antidepressants of different classes.

Journal: Clinics (Sao Paulo, Brazil) 20110201

Title: AIF-mediated mitochondrial pathway is critical for the protective effect of diazoxide against SH-SY5Y cell apoptosis.

Journal: Brain research 20110125

Title: Diazoxide attenuates indomethacin-induced small intestinal damage in the rat.

Journal: European journal of pharmacology 20110110

Title: The pancreas in human type 1 diabetes.

Journal: Seminars in immunopathology 20110101

Title: Reversal of rotenone-induced dysfunction of astrocytic connexin43 by opening mitochondrial ATP-sensitive potassium channels.

Journal: Cellular and molecular neurobiology 20110101

Title: Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice.

Journal: Diabetes 20110101

Title: Familial focal congenital hyperinsulinism.

Journal: The Journal of clinical endocrinology and metabolism 20110101

Title: Congenital hyperinsulinism and glucose hypersensitivity in homozygous and heterozygous carriers of Kir6.2 (KCNJ11) mutation V290M mutation: K(ATP) channel inactivation mechanism and clinical management.

Journal: Diabetes 20110101

Title: Cardiac glycosides are potent inhibitors of interferon-β gene expression.

Journal: Nature chemical biology 20110101

Title: Isoflurane preconditioning increases endothelial cell tolerance to in-vitro simulated ischaemia.

Journal: The Journal of pharmacy and pharmacology 20110101

Title: Elimination of hypoglycemia from the lives of people affected by diabetes.

Journal: Diabetes 20110101

Title: TRP-ing down the path to insulin secretion.

Journal: Diabetes 20110101

Title: Everolimus resolving hypoglycemia, producing hyperglycemia, and necessitating insulin use in a patient with diabetes and nonresectable malignant insulinoma.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101

Title: Metastatic insulinoma in a patient with type 2 diabetes mellitus: case report and review of the literature.

Journal: International journal of endocrinology 20110101

Title: Continuous glucose monitoring for evaluation of glycemic excursions after gastric bypass.

Journal: Journal of obesity 20110101

Title: New developments in the treatment of hyperammonemia: emerging use of carglumic acid.

Journal: International journal of general medicine 20110101

Title: Molecular mechanisms in exercise-induced cardioprotection.

Journal: Cardiology research and practice 20110101

Title: Expression of ATP-sensitive potassium channels in human pregnant myometrium.

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: Regulation of gap junctional communication by astrocytic mitochondrial K(ATP) channels following neurotoxin administration in in vitro and in vivo models.

Journal: Neuro-Signals 20110101

Title: Evidence for presence and functional effects of Kv1.1 channels in β-cells: general survey and results from mceph/mceph mice.

Journal: PloS one 20110101

Title: Nateglinide stimulates glucagon-like peptide-1 release by human intestinal L cells via a K(ATP) channel-independent mechanism.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Role of the nitric oxide on relaxation of the human umbilical artery during cooling.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101

Title: Cardioprotective effect of nicorandil, a mitochondrial ATP-sensitive potassium channel opener, prolongs survival in HSPB5 R120G transgenic mice.

Journal: PloS one 20110101

Title: Mitochondrial approaches to protect against cardiac ischemia and reperfusion injury.

Journal: Frontiers in physiology 20110101

Title: Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats.

Journal: Molecular pain 20110101

Title: Pharmacological modulation of dopamine receptor D2-mediated transmission alters the metabolic phenotype of diet induced obese and diet resistant C57Bl6 mice.

Journal: Experimental diabetes research 20110101

Title: Hypothalamic Obesity following Craniopharyngioma Surgery: Results of a Pilot Trial of Combined Diazoxide and Metformin Therapy.

Journal: International journal of pediatric endocrinology 20110101

Title: Role of Kv1 potassium channels in regulating dopamine release and presynaptic D2 receptor function.

Journal: PloS one 20110101

Title: MicroRNAs in cardiovascular disease.

Journal: F1000 medicine reports 20110101

Title: Evolving diagnostic and treatment strategies for pancreatic neuroendocrine tumors.

Journal: Journal of hematology & oncology 20110101

Title: Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1.

Journal: PloS one 20110101

Title: Modulation of myocardial mitochondrial mechanisms during severe polymicrobial sepsis in the rat.

Journal: PloS one 20110101

Title: Lack of Restoration in Vivo by K-Channel Modulators of Jejunal Fluid Absorption after Heat Stable Escherichia coli Enterotoxin (STa) Challenge.

Journal: Journal of tropical medicine 20110101

Title: Hypoglycemic syndrome in a patient with proinsulin-only secreting pancreatic adenoma (proinsulinoma).

Journal: Case reports in medicine 20110101

Title: Stem cells for cardiac repair: status, mechanisms, and new strategies.

Journal: Stem cells international 20110101

Title: Analysis of mitochondrial 3D-deformation in cardiomyocytes during active contraction reveals passive structural anisotropy of orthogonal short axes.

Journal: PloS one 20110101

Title: Octreotide-treated diabetes accompanied by endogenous hyperinsulinemic hypoglycemia and protein-losing gastroenteropathy.

Journal: Case reports in medicine 20110101

Title: [Congenital hyperinsulinism in the north-east Netherlands. Clinical features and DNA diagnostics in 22 children].

Journal: Nederlands tijdschrift voor geneeskunde 20110101

Title: ATP-Sensitive Potassium Channel Currents in Eccentrically Hypertrophied Cardiac Myocytes of Volume-Overloaded Rats.

Journal: International journal of cell biology 20110101

Title: [The influence of ATP-dependent K(+)-channel diazoxide opener on the opening of mitochondrial permeability transition pore in rat liver mitochondria].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

Title: [Regulation of the mitochondrial ATP-sensitive potassium channel in rat uterus cells by ROS].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

Title: Control of the intracellular redox state by glucose participates in the insulin secretion mechanism.

Journal: PloS one 20110101

Title: Pulmonary hypertension and reopening of the ductus arteriosus in an infant treated with diazoxide.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20110101

Title: Short- and long-term physiologic and pharmacologic control of blood pressure in pediatric patients.

Journal: Integrated blood pressure control 20110101

Title: Congenital hyperinsulinism: current trends in diagnosis and therapy.

Journal: Orphanet journal of rare diseases 20110101

Title: High-throughput assay for the identification of compounds regulating osteogenic differentiation of human mesenchymal stromal cells.

Journal: PloS one 20110101

Title: Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis.

Journal: Journal of neuroinflammation 20110101

Title: MiR-146a in Immunity and Disease.

Journal: Molecular biology international 20110101

Title: Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats.

Journal: Cardiovascular diabetology 20110101

Title: Hyperinsulinism associated with gestational exposure to bupropion in a newborn infant.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20110101

Title: Measurement of warfarin in the oral fluid of patients undergoing anticoagulant oral therapy.

Journal: PloS one 20110101

Title: [Ontogeny of sulphonylurea-binding regulatory subunits of K(ATP) channels in the pregnant rat myometrium].

Journal: Acta pharmaceutica Hungarica 20110101

Title: Clinical characteristics of recessive and dominant congenital hyperinsulinism due to mutation(s) in the ABCC8/KCNJ11 genes encoding the ATP-sensitive potasium channel in the pancreatic beta cell.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20110101

Title: Long term sequelae of pediatric craniopharyngioma - literature review and 20 years of experience.

Journal: Frontiers in endocrinology 20110101

Title: Effects of methylphenidate on weight gain and food intake in hypothalamic obesity.

Journal: Frontiers in endocrinology 20110101

Title: Hypothalamic obesity after craniopharyngioma: mechanisms, diagnosis, and treatment.

Journal: Frontiers in endocrinology 20110101

Title: Paternal Uniparental Isodisomy of Chromosome 11p15.5 within the Pancreas Causes Isolated Hyperinsulinemic Hypoglycemia.

Journal: Frontiers in endocrinology 20110101

Title: Neonatal hyperinsulinism secondary to maternal intake of high-sugar drinks.

Journal: BMJ case reports 20110101

Title: Rapidly progressing malignant insulinoma presented with multiple liver metastases: a case report.

Journal: Journal of gastrointestinal cancer 20101201

Title: Diazoxide attenuates hypothermic preservation-induced renal injury via down-regulation of CHOP and caspase-12.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101201

Title: Both mitochondrial KATP channel opening and sarcolemmal KATP channel blockage confer protection against ischemia/reperfusion-induced arrhythmia in anesthetized male rats.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: Adenosine A(1) and A (3) receptor agonists reduce hypoxic injury through the involvement of P38 MAPK.

Journal: Molecular and cellular biochemistry 20101201

Title: Role of KATP and L-type Ca2+ channel activities in regulation of ovine uterine vascular contractility: effect of pregnancy and chronic hypoxia.

Journal: American journal of obstetrics and gynecology 20101201

Title: Myocardial ischaemic and diazoxide preconditioning both increase PGC-1alpha and reduce mitochondrial damage.

Journal: Acta cardiologica 20101201

Title: Hyperinsulinemic hypoglycemia evolving to gestational diabetes and diabetes mellitus in a family carrying the inactivating ABCC8 E1506K mutation.

Journal: Pediatric diabetes 20101101

Title: Pharmacological preconditioning by diazoxide downregulates cardiac L-type Ca(2+) channels.

Journal: British journal of pharmacology 20101101

Title: Discrimination between two possible reaction sequences that create potential risk of generation of deleterious radicals by cytochrome bc₁. Implications for the mechanism of superoxide production.

Journal: Biochimica et biophysica acta 20101101

Title: ABCC8 and KCNJ11 molecular spectrum of 109 patients with diazoxide-unresponsive congenital hyperinsulinism.

Journal: Journal of medical genetics 20101101

Title: Roles of phospho-GSK-3β in myocardial protection afforded by activation of the mitochondrial K ATP channel.

Journal: Journal of molecular and cellular cardiology 20101101

Title: Management of intractable hypoglycemia with Yttirum-90 radioembolization in a patient with malignant insulinoma.

Journal: The American journal of the medical sciences 20101101

Title: Hypoglycaemia following gastric bypass surgery--diabetes remission in the extreme?

Journal: Diabetologia 20101101

Title: Diazoxide maintenance of myocyte volume and contractility during stress: evidence for a non-sarcolemmal K(ATP) channel location.

Journal: The Journal of thoracic and cardiovascular surgery 20101101

Title: Microfluidic multi-analyte gradient generator.

Journal: Analytical and bioanalytical chemistry 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: 3-(6-Fluoro-4-oxo-4H-chromen-3-yl)-3,4-dihydro-2H-1,2,4-benzothia-diazine-1,1-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Mechanisms of the beneficial actions of ischemic preconditioning on subcellular remodeling in ischemic-reperfused heart.

Journal: Current cardiology reviews 20101101

Title: Management of postgastric bypass noninsulinoma pancreatogenous hypoglycemia.

Journal: Surgical endoscopy 20101001

Title: Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning.

Journal: Cardiovascular research 20101001

Title: Endothelin signalling regulates volume-sensitive Cl- current via NADPH oxidase and mitochondrial reactive oxygen species.

Journal: Cardiovascular research 20101001

Title: MicroRNA-21 is a key determinant in IL-11/Stat3 anti-apoptotic signalling pathway in preconditioning of skeletal myoblasts.

Journal: Cardiovascular research 20101001

Title: Diazoxide preconditioning alleviates caspase-dependent and caspase-independent apoptosis induced by anoxia-reoxygenation of PC12 cells.

Journal: Journal of biochemistry 20101001

Title: Diazoxide potentiates mesenchymal stem cell survival via NF-kappaB-dependent miR-146a expression by targeting Fas.

Journal: American journal of physiology. Heart and circulatory physiology 20101001

Title: Regulation of AMPA receptor currents by mitochondrial ATP-sensitive K+ channels in anoxic turtle neurons.

Journal: Journal of neurophysiology 20101001

Title: The effect of 'Teucrium polium L.' extracts on insulin release from in situ isolated perfused rat pancreas in a newly modified isolation method: the role of Ca2+ and K+ channels.

Journal: Iranian biomedical journal 20101001

Title: Potassium channel openers exhibit cross-tolerance with morphine in two experimental models of pain.

Journal: The West Indian medical journal 20101001

Title: Targeting hypertension with a new adenosine triphosphate-sensitive potassium channel opener iptakalim.

Journal: Journal of cardiovascular pharmacology 20100901

Title: Subplasmalemmal Ca(2+) measurements in mouse pancreatic beta cells support the existence of an amplifying effect of glucose on insulin secretion.

Journal: Diabetologia 20100901

Title: Autonomic neuropathy predisposes to rosiglitazone-induced vascular leakage in insulin-treated patients with type 2 diabetes: a randomised, controlled trial on thiazolidinedione-induced vascular leakage.

Journal: Diabetologia 20100901

Title: Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets.

Journal: Diabetes 20100901

Title: Hyperinsulinemia precedes insulin resistance in mice lacking pancreatic beta-cell leptin signaling.

Journal: Endocrinology 20100901

Title: 17 β-estradiol rapidly increases ATP-sensitive potassium channel activity in gonadotropin-releasing hormone neurons [corrected] via a protein kinase signaling pathway.

Journal: Endocrinology 20100901

Title: Advanced diagnostic approaches and current medical management of insulinomas and adrenocortical disease in ferrets (Mustela putorius furo).

Journal: The veterinary clinics of North America. Exotic animal practice 20100901

Title: Congenital hyperinsulinism due to mutations in HNF4A and HADH.

Journal: Reviews in endocrine & metabolic disorders 20100901

Title: The hyperinsulinism/hyperammonemia syndrome.

Journal: Reviews in endocrine & metabolic disorders 20100901

Title: Influence of ATP-dependent K(+)-channel opener on K(+)-cycle and oxygen consumption in rat liver mitochondria.

Journal: Biochemistry. Biokhimiia 20100901

Title: Vascular dysfunctions following spinal cord injury.

Journal: Journal of medicine and life 20100815

Title: Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: Effects of high-density lipoproteins on pancreatic beta-cell insulin secretion.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100801

Title: Autophagy induced by ischemic preconditioning is essential for cardioprotection.

Journal: Journal of cardiovascular translational research 20100801

Title: AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets.

Journal: Molecular and cellular endocrinology 20100729

Title: Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.

Journal: The Biochemical journal 20100715

Title: Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations.

Journal: Biophysical journal 20100707

Title: Biotin increases glucokinase expression via soluble guanylate cyclase/protein kinase G, adenosine triphosphate production and autocrine action of insulin in pancreatic rat islets.

Journal: The Journal of nutritional biochemistry 20100701

Title: Human K(ATP) channelopathies: diseases of metabolic homeostasis.

Journal: Pflugers Archiv : European journal of physiology 20100701

Title: Mitochondria as a source of mechanical signals in cardiomyocytes.

Journal: Cardiovascular research 20100701

Title: Transient anoxia and oxyradicals induce a region-specific activation of MAPKs in the embryonic heart.

Journal: Molecular and cellular biochemistry 20100701

Title: Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells.

Journal: Diabetes 20100701

Title: Persistent hyperinsulinemic hypoglycemia of infancy due to homozygous KCNJ11 (T294M) mutation.

Journal: Indian journal of pediatrics 20100701

Title: A study of the relationship between pharmacologic preconditioning and adenosine triphosphate-sensitive potassium (KATP) channels on cultured cardiomyocytes using the microelectrode array.

Journal: Journal of cardiovascular pharmacology 20100701

Title: [Effect of K-ATP channel opener diazoxide on islet cell apoptosis and the expressions of apoptosis-related genes].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100701

Title: Anemia and neutropenic fever with high dose diazoxide treatment in a case with hyperinsulinism due to Munchausen by proxy.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20100701

Title: Two unrelated Chinese patients with hyperinsulinism /hyperammonemia (HI/HA) syndrome due to mutations in glutamate dehydrogenase gene.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20100701

Title: Effects of mitochondrial potassium channel and membrane potential on hypoxic human pulmonary artery smooth muscle cells.

Journal: American journal of respiratory cell and molecular biology 20100601

Title: Low-level arsenic impairs glucose-stimulated insulin secretion in pancreatic beta cells: involvement of cellular adaptive response to oxidative stress.

Journal: Environmental health perspectives 20100601

Title: Octreotide's role in the management of sulfonylurea-induced hypoglycemia.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20100601

Title: Signaling pathways involved in postconditioning-induced cardioprotection of human myocardium, in vitro.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100601

Title: Mechanisms of hydrogen peroxide-induced vasoconstriction in the isolated perfused rat kidney.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601

Title: The phosphatidylinositol-3 kinase/Akt pathway mediates geranylgeranylacetone-induced neuroprotection against cerebral infarction in rats.

Journal: Brain research 20100512

Title: Connexin 43 acts as a cytoprotective mediator of signal transduction by stimulating mitochondrial KATP channels in mouse cardiomyocytes.

Journal: The Journal of clinical investigation 20100503

Title: Diazoxide reduces status epilepticus neuron damage in diabetes.

Journal: Neurotoxicity research 20100501

Title: Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles.

Journal: Diabetes 20100501

Title: Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations.

Journal: European journal of endocrinology 20100501

Title: Therapies for the medical management of persistent hypoglycaemia in two cases of inoperable malignant insulinoma.

Journal: European journal of endocrinology 20100501

Title: Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia.

Journal: American journal of physiology. Endocrinology and metabolism 20100501

Title: Congenital hyperinsulinism.

Journal: Early human development 20100501

Title: Involvement of mitochondrial ATP-sensitive potassium channels in etomidate preconditioning-induced protection in human myeloid HL-60 cells.

Journal: Environmental toxicology and pharmacology 20100501

Title: A lethargic neonate and an infant with seizure.

Journal: Clinical pediatrics 20100401

Title: Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation.

Journal: Molecular and cellular biochemistry 20100401

Title: Uncoupling between insulin and release of a D-chiro-inositol-containing inositolphosphoglycan mediator of insulin action in obese women With polycystic ovary syndrome.

Journal: Metabolic syndrome and related disorders 20100401

Title: Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection.

Journal: The Journal of physiology 20100401

Title: The intracellular localization and function of the ATP-sensitive K+ channel subunit Kir6.1.

Journal: The Journal of membrane biology 20100401

Title: [Influence of diazoxide on mitochondrial apoptosis in human renal tubular cells induced by serum obtained from neonates with asphyxia].

Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20100401

Title: Inhibition of endogenous hydrogen sulfide synthesis by PAG protects against ethanol-induced gastric damage in the rat.

Journal: European journal of pharmacology 20100325

Title: Preconditioning promotes survival and angiomyogenic potential of mesenchymal stem cells in the infarcted heart via NF-kappaB signaling.

Journal: Antioxidants & redox signaling 20100315

Title: Six months of diazoxide treatment at bedtime in newly diagnosed subjects with type 1 diabetes does not influence parameters of {beta}-cell function and autoimmunity but improves glycemic control.

Journal: Diabetes care 20100301

Title: The KATP channel is a molecular sensor of atrophy in skeletal muscle.

Journal: The Journal of physiology 20100301

Title: Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts.

Journal: Journal of Korean medical science 20100301

Title: Recurrent hypoglycaemia in a type 2 diabetes patient - diagnostic difficulties.

Journal: Archives of medical science : AMS 20100301

Title: [Akt involved in diazoxide preconditioning against rat hippocampal neuronal apoptosis induced by anoxia-reoxygenation injury].

Journal: Zhonghua yi xue za zhi 20100223

Title: K(ATP) channel openers protect mesencephalic neurons against MPP+-induced cytotoxicity via inhibition of ROS production.

Journal: Journal of neuroscience research 20100201

Title: Variable effects of the mitoK(ATP) channel modulators diazoxide and 5-HD in ATP-depleted renal epithelial cells.

Journal: Molecular and cellular biochemistry 20100201

Title: Coupling of liquid chromatography/tandem mass spectrometry and liquid chromatography/solid-phase extraction/NMR techniques for the structural identification of metabolites following in vitro biotransformation of SUR1-selective ATP-sensitive potassium channel openers.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100201

Title: Inhibition of oxygen consumption in skeletal muscle-derived mitochondria by pinacidil, diazoxide, and glibenclamide, but not by 5-hydroxydecanoate.

Journal: Journal of bioenergetics and biomembranes 20100201

Title: Sevoflurane pre- and post-conditioning protect the brain via the mitochondrial K ATP channel.

Journal: British journal of anaesthesia 20100201

Title: Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channels.

Journal: British journal of pharmacology 20100201

Title: Transplantation of mesenchymal stem cells preconditioned with diazoxide, a mitochondrial ATP-sensitive potassium channel opener, promotes repair of myocardial infarction in rats.

Journal: The Tohoku journal of experimental medicine 20100201

Title: [Effects of diazoxide on the mitochondrial ultrastructure and permeability in donor rat myocardium].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100201

Title: Ischemic postconditioning may not influence early brain injury induced by focal cerebral ischemia/reperfusion in rats.

Journal: Korean journal of anesthesiology 20100201

Title: Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice.

Journal: European journal of pharmacology 20100125

Title: [Effect of diazoxide on oxygen free radicals and cell apoptosis in brain tissue after deep hypothermia cerebral ischemia reperfusion injury in young rats].

Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20100115

Title: Chloro-substituted 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel activators: impact of the position of the chlorine atom on the aromatic ring on activity and tissue selectivity.

Journal: Journal of medicinal chemistry 20100114

Title: Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture.

Journal: Journal of molecular and cellular cardiology 20100101

Title: Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel.

Journal: Biochemical pharmacology 20100101

Title: Terminalia bellirica stimulates the secretion and action of insulin and inhibits starch digestion and protein glycation in vitro.

Journal: The British journal of nutrition 20100101

Title: Differential K(ATP) channel pharmacology in intact mouse heart.

Journal: Journal of molecular and cellular cardiology 20100101

Title: ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation.

Journal: Diabetes 20100101

Title: Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume.

Journal: The Journal of biological chemistry 20100101

Title: Modeling mitochondrial bioenergetics with integrated volume dynamics.

Journal: PLoS computational biology 20100101

Title: Direct effects of K(ATP) channel openers pinacidil and diazoxide on oxidative phosphorylation of mitochondria in situ.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: Defective secretion of islet hormones in chromogranin-B deficient mice.

Journal: PloS one 20100101

Title: Congenital hyperinsulinism due to a compound heterozygous ABCC8 mutation with spontaneous resolution at eight weeks.

Journal: Hormone research in paediatrics 20100101

Title: Novel neuroprotective strategies in ischemic retinal lesions.

Journal: International journal of molecular sciences 20100101

Title: Insulinoma in a patient with MEN 1 syndrome--9-year follow-up: case report.

Journal: Endokrynologia Polska 20100101

Title: Potent cardioprotective effect of the 4-anilinoquinazoline derivative PD153035: involvement of mitochondrial K(ATP) channel activation.

Journal: PloS one 20100101

Title: Diazoxide promotes oligodendrocyte precursor cell proliferation and myelination.

Journal: PloS one 20100101

Title: Hypoglycaemia following upper gastrointestinal surgery: case report and review of the literature.

Journal: BMC gastroenterology 20100101

Title: Nonclassic congenital adrenal hyperplasia.

Journal: International journal of pediatric endocrinology 20100101

Title: Dual role of nNOS in ischemic injury and preconditioning.

Journal: BMC physiology 20100101

Title: Mitochondrial preconditioning: a potential neuroprotective strategy.

Journal: Frontiers in aging neuroscience 20100101

Title: The KATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Electrical short-circuit in β-cells from a patient with non-insulinoma pancreatogenous hypoglycemic syndrome (NIPHS): a case report.

Journal: Journal of medical case reports 20100101

Title: Neuroprotective properties of levosimendan in an in vitro model of traumatic brain injury.

Journal: BMC neurology 20100101

Title: Hyperinsulinemic hypoglycemias in infancy and childhood--diagnostic therapeutic algorithm with contribution of two cases.

Journal: Folia medica 20100101

Title: Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.

Journal: PloS one 20100101

Title: Endocrinology of hirsutism.

Journal: International journal of trichology 20100101

Title: [Effect of mitochondrial ATP-dependent potassium channel effectors diazoxide and glybenclamide on hydrodynamic diameter and membrane potential of the myometrial mitochondria].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20100101

Title: Magnesium Lithospermate B Protects Cardiomyocytes from Ischemic Injury Via Inhibition of TAB1-p38 Apoptosis Signaling.

Journal: Frontiers in pharmacology 20100101

Title: Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project.

Journal: Clinical pharmacology : advances and applications 20100101

Title: Congenital hyperinsulinism with hyperammonaemia.

Journal: BMJ case reports 20100101

Title: Diazoxide protects against hydrogen peroxide-induced toxicity in the osteoblastic MC3T3-E1 cells.

Journal: European journal of pharmacology 20091210

Title: Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules.

Journal: Cell metabolism 20091202

Title: Congenital disorder of glycosylation type Ia: heterogeneity in the clinical presentation from multivisceral failure to hyperinsulinaemic hypoglycaemia as leading symptoms in three infants with phosphomannomutase deficiency.

Journal: Journal of inherited metabolic disease 20091201

Title: Diazoxide reverses the enhanced expression of KATP subunits in cholinergic neurons caused by exposure to Aβ₁₋₄₂.

Journal: Neurochemical research 20091201

Title: Glucose deprivation regulates KATP channel trafficking via AMP-activated protein kinase in pancreatic beta-cells.

Journal: Diabetes 20091201

Title: Galanin potentiates supramaximal caerulein-stimulated pancreatic amylase secretion via its action on somatostatin secretion.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20091201

Title: Mitochondrial KATP opening confers protection against lethal myocardial injury and ischaemia-induced arrhythmias in the rat heart via PI3K/Akt-dependent and -independent mechanisms.

Journal: Canadian journal of physiology and pharmacology 20091201

Title: Bistability of mitochondrial respiration underlies paradoxical reactive oxygen species generation induced by anoxia.

Journal: PLoS computational biology 20091201

Title: Distinct effects of CGRP on typical and atypical smooth muscle cells involved in generating spontaneous contractions in the mouse renal pelvis.

Journal: British journal of pharmacology 20091201

Title: Molecular identification and functional characterization of a mitochondrial sulfonylurea receptor 2 splice variant generated by intraexonic splicing.

Journal: Circulation research 20091120

Title: New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position.

Journal: Bioorganic & medicinal chemistry 20091115

Title: Early preconditioning protection against stunning in conscious sheep. Role of KATP channels.

Journal: Molecular and cellular biochemistry 20091101

Title: Mitogen-activated protein kinase p38alpha and retinal ischemic preconditioning.

Journal: Experimental eye research 20091101

Title: Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations.

Journal: European journal of endocrinology 20091101

Title: Synthesis of modified 4H-1,2,4-benzothiadiazine-1,1-dioxides and determination of their affinity and selectivity for different types of K(ATP) channels.

Journal: ChemMedChem 20091101

Title: Beneficial effects of K-ATP channel openers in diabetes: an update on mechanisms and clinical experiences.

Journal: Diabetes, obesity & metabolism 20091101

Title: The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion.

Journal: Anesthesia and analgesia 20091101

Title: Quantitative measurement of zinc secretion from pancreatic islets with high temporal resolution using droplet-based microfluidics.

Journal: Analytical chemistry 20091101

Title: Immunotherapy for the prevention and treatment of type 1 diabetes: human trials and a look into the future.

Journal: Diabetes care 20091001

Title: [Persistent hyperinsulinemic hypoglycemia of infancy: clinical analysis of 12 cases].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20091001

Title: Phosphorylation of connexin-43 at serine 262 promotes a cardiac injury-resistant state.

Journal: Cardiovascular research 20090901

Title: Angiotensin II and tumour necrosis factor alpha as mediators of ATP-dependent potassium channel remodelling in post-infarction heart failure.

Journal: Cardiovascular research 20090901

Title: Successful medical management of status post-Roux-en-Y-gastric-bypass hyperinsulinemic hypoglycemia.

Journal: Obesity surgery 20090901

Title: Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases.

Journal: The Journal of clinical endocrinology and metabolism 20090901

Title: Radiofrequency ablation of solitary pancreatic insulinoma in a patient with episodes of severe hypoglycemia.

Journal: European journal of gastroenterology & hepatology 20090901

Title: ATP-sensitive potassium currents in rat primary afferent neurons: biophysical, pharmacological properties, and alterations by painful nerve injury.

Journal: Neuroscience 20090818

Title: Lysosomal and proteasome-dependent proteolysis are differentially regulated by insulin and/or amino acids following feeding in young, mature and old rats.

Journal: The Journal of nutritional biochemistry 20090801

Title: Deletion of PKCepsilon selectively enhances the amplifying pathways of glucose-stimulated insulin secretion via increased lipolysis in mouse beta-cells.

Journal: Diabetes 20090801

Title: Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop.

Journal: Diabetes 20090801

Title: Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells.

Journal: Diabetologia 20090801

Title: Isoflurane induces a postconditioning effect on bovine pulmonary arterial endothelial cells exposed to oxygen-glucose deprivation.

Journal: European journal of pharmacology 20090801

Title: Plasma membrane depolarization as a determinant of the first phase of insulin secretion.

Journal: American journal of physiology. Endocrinology and metabolism 20090801

Title: Galanin inhibits caerulein-stimulated pancreatic amylase secretion via cholinergic nerves and insulin.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20090801

Title: Glucose sensing during hypoglycemia: lessons from the lab.

Journal: Diabetes care 20090801

Title: Hypoglycemia: from the laboratory to the clinic.

Journal: Diabetes care 20090801

Title: [Diabetes counteracts the protective effect of the diazoxide preconditioning on ischemic reperfused rat heart].

Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20090801

Title: Role of mitochondrial ATP-sensitive potassium channels on fatigue in mouse muscle fibers.

Journal: Biochemical and biophysical research communications 20090717

Title: Evidence for an ATP-sensitive K+ channel in mitoplasts isolated from Trypanosoma cruzi and Crithidia fasciculata.

Journal: International journal for parasitology 20090715

Title: Inhibitory effects of leptin on pancreatic alpha-cell function.

Journal: Diabetes 20090701

Title: 3-Hydroxyacyl-coenzyme A dehydrogenase deficiency and hyperinsulinemic hypoglycemia: characterization of a novel mutation and severe dietary protein sensitivity.

Journal: The Journal of clinical endocrinology and metabolism 20090701

Title: Sesquiterpenoids from antidiabetic Psacalium decompositum block ATP sensitive potassium channels.

Journal: Journal of ethnopharmacology 20090625

Title: Hyperinsulinaemic hypoglycaemia.

Journal: Archives of disease in childhood 20090601

Title: The phenomenon of seasonal pseudohypokalemia: effects of ambient temperature, plasma glucose and role for sodium-potassium-exchanging-ATPase.

Journal: Clinical biochemistry 20090601

Title: Extremes of clinical and enzymatic phenotypes in children with hyperinsulinism caused by glucokinase activating mutations.

Journal: Diabetes 20090601

Title: Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain complexes I and III.

Journal: Biochimica et biophysica acta 20090601

Title: Role of the nitric oxide on diazoxide-induced relaxation of the calf cardiac vein and coronary artery during cooling.

Journal: Fundamental & clinical pharmacology 20090601

Title: Intermittent adenosine at the beginning of reperfusion does not trigger cardioprotection.

Journal: The Journal of surgical research 20090515

Title: ATP-sensitive potassium channels control glioma cells proliferation by regulating ERK activity.

Journal: Carcinogenesis 20090501

Title: Oleic acid directly regulates POMC neuron excitability in the hypothalamus.

Journal: Journal of neurophysiology 20090501

Title: Possible role of JAK-2 in attenuated cardioprotective effect of ischemic preconditioning in hyperhomocysteinemic rat hearts.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090501

Title: Cardiac dysfunctions following spinal cord injury.

Journal: Journal of medicine and life 20090415

Title: Leptin-dependent phosphorylation of PTEN mediates actin restructuring and activation of ATP-sensitive K+ channels.

Journal: The Journal of biological chemistry 20090403

Title: Iptakalim protects against MPP+-induced degeneration of dopaminergic neurons in association with astrocyte activation.

Journal: The international journal of neuropsychopharmacology 20090401

Title: Iptakalim ameliorates MPP+-induced astrocyte mitochondrial dysfunction by increasing mitochondrial complex activity besides opening mitoK(ATP) channels.

Journal: Journal of neuroscience research 20090401

Title: Glucose-dependent and -independent electrical activity in islets of Langerhans of Psammomys obesus, an animal model of nutritionally induced obesity and diabetes.

Journal: General and comparative endocrinology 20090401

Title: Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets.

Journal: Diabetologia 20090401

Title: Endothelial heparanase secretion after acute hypoinsulinemia is regulated by glucose and fatty acid.

Journal: American journal of physiology. Heart and circulatory physiology 20090401

Title: Identification of a chemical probe for NAADP by virtual screening.

Journal: Nature chemical biology 20090401

Title: Diazoxide protects myocardial mitochondria, metabolism, and function during cardiac surgery: a double-blind randomized feasibility study of diazoxide-supplemented cardioplegia.

Journal: The Journal of thoracic and cardiovascular surgery 20090401

Title: The insulinotropic effect of fluoroquinolones.

Journal: Biochemical pharmacology 20090315

Title: Involvement of hippocampal CA3 K(ATP) channels in contextual memory.

Journal: Neuropharmacology 20090301

Title: Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth.

Journal: Diabetes 20090301

Title: The role of Akt/protein kinase B subtypes in retinal ischemic preconditioning.

Journal: Experimental eye research 20090301

Title: Nicorandil attenuates FeCl(3)-induced thrombus formation through the inhibition of reactive oxygen species production.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20090301

Title: A new mechanism and strategy for inhibiting thrombus formation in the artery.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20090301

Title: [Regulation of rat airway smooth muscle cell proliferation by mitochondrial ATP-sensitive K(+) channel in asthmic rats.].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20090225

Title: Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090201

Title: Glucose and pharmacological modulators of ATP-sensitive K+ channels control [Ca2+]c by different mechanisms in isolated mouse alpha-cells.

Journal: Diabetes 20090201

Title: Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice.

Journal: Diabetes 20090201

Title: Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells.

Journal: Diabetologia 20090201

Title: The alpha-cell conundrum: ATP-sensitive K+ channels and glucose sensing.

Journal: Diabetes 20090201

Title: Effects of ATP-sensitive potassium channels on the expression of P21, P27 and leptin.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090201

Title: Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways.

Journal: The Journal of biological chemistry 20090123

Title: Effect of obestatin on insulin, glucagon and somatostatin secretion in the perfused rat pancreas.

Journal: Regulatory peptides 20090108

Title: Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial K(ATP) channels and reactive oxygen species.

Journal: Physiological research 20090101

Title: Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

Journal: Endocrinology 20090101

Title: Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells.

Journal: Diabetes 20090101

Title: Diazoxide-mediated growth inhibition in human lung cancer cells via downregulation of beta-catenin-mediated cyclin D1 transcription.

Journal: Lung 20090101

Title: Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization.

Journal: Journal of Alzheimer's disease : JAD 20090101

Title: Laparoscopic pancreatectomy for persistent hyperinsulinemic hypoglycemia of infancy.

Journal: Journal of pediatric surgery 20090101

Title: Pancreatic insulinoma co-existing with gastric GIST in the absence of neurofibromatosis-1.

Journal: World journal of surgical oncology 20090101

Title: Connexins: a myriad of functions extending beyond assembly of gap junction channels.

Journal: Cell communication and signaling : CCS 20090101

Title: Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation.

Journal: Molecular pain 20090101

Title: Childhood craniopharyngioma: greater hypothalamic involvement before surgery is associated with higher homeostasis model insulin resistance index.

Journal: BMC pediatrics 20090101

Title: Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion.

Journal: PloS one 20090101

Title: The mitochondrial ATP-sensitive potassium channel blocker 5-hydroxydecanoate inhibits toxicity of 6-hydroxydopamine on dopaminergic neurons.

Journal: Neurotoxicity research 20090101

Title: Reducing stillbirths: prevention and management of medical disorders and infections during pregnancy.

Journal: BMC pregnancy and childbirth 20090101

Title: [Effect of adenosine triphosphate-dependent potassium channel activators on electrical reactions of intact and cultured endothelial cells].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101

Title: The role of ATP-sensitive potassium channel blockers in ischemia-reperfusion-induced renal injury versus their effects on cardiac ischemia reperfusion in rats.

Journal: European review for medical and pharmacological sciences 20090101

Title: Impact of modulators of mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) on hypoxic pulmonary vasoconstriction.

Journal: Advances in experimental medicine and biology 20090101

Title: Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation.

Journal: BMC cell biology 20090101

Title: Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits.

Journal: Journal of cardiothoracic surgery 20090101

Title: [Diagnostics and treatment of organic hyperinsulinism--experience in 105 cases].

Journal: Casopis lekaru ceskych 20090101

Title: Neuroprotective effects of diazoxide and its antagonism by glibenclamide in pyramidal neurons of rat hippocampus subjected to ischemia-reperfusion-induced injury.

Journal: The International journal of neuroscience 20090101

Title: Acute dystonic reactions in a lady presenting with repetitive involuntary muscle twitching: a case report.

Journal: Cases journal 20090101

Title: Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets.

Journal: PloS one 20090101

Title: Role of potassium channels in stretch-promoted atrial natriuretic factor secretion.

Journal: Journal of the American Society of Hypertension : JASH 20090101

Title: Possible role of an ischemic preconditioning-like response mechanism in K(ATP) channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function.

Journal: Biochemical pharmacology 20081215

Title: Differential structure of atrial and ventricular KATP: atrial KATP channels require SUR1.

Journal: Circulation research 20081205

Title: Weight loss in obese men by caloric restriction and high-dose diazoxide-mediated insulin suppression.

Journal: Diabetes, obesity & metabolism 20081201

Title: Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel.

Journal: Cardiovascular research 20081201

Title: Amplified hormonal counterregulatory responses to hypoglycemia in rats after systemic delivery of a SUR-1-selective K(+) channel opener?

Journal: Diabetes 20081201

Title: Na+/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20081201

Title: A peptide of the phylloseptin family from the skin of the frog Hylomantis lemur (Phyllomedusinae) with potent in vitro and in vivo insulin-releasing activity.

Journal: Peptides 20081201

Title: Synthesis and pharmacological evaluation of a second generation of pyridothiadiazine 1,1-dioxides acting as AMPA potentiators.

Journal: Bioorganic & medicinal chemistry 20081201

Title: Minimizing hypoglycemia while maintaining glycemic control in diabetes.

Journal: Diabetes 20081201

Title: American College of Endocrinology Pre-Diabetes Consensus Conference: part three.

Journal: Diabetes care 20081201

Title: Long lasting synchronization of calcium oscillations by cholinergic stimulation in isolated pancreatic islets.

Journal: Biophysical journal 20081115

Title: Preconditioning by an in situ administration of hydrogen peroxide: involvement of reactive oxygen species and mitochondrial ATP-dependent potassium channel in a cerebral ischemia-reperfusion model.

Journal: Brain research 20081113

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel.

Journal: Journal of medicinal chemistry 20081113

Title: The L-Type Ca+ and KATP channels may contribute to pacing-induced protection against anoxia-reoxygenation in the embryonic heart model.

Journal: Journal of cardiovascular electrophysiology 20081101

Title: Coassembly of different sulfonylurea receptor subtypes extends the phenotypic diversity of ATP-sensitive potassium (KATP) channels.

Journal: Molecular pharmacology 20081101

Title: Chronic sustained and intermittent hypoxia reduce function of ATP-sensitive potassium channels in nucleus of the solitary tract.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20081101

Title: Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats.

Journal: Metabolism: clinical and experimental 20081101

Title: Involvement of mitoKATP channel in protective mechanisms of cerebral ischemic tolerance.

Journal: Brain research 20081031

Title: Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells.

Journal: The Journal of endocrinology 20081001

Title: Protein kinase C subtypes and retinal ischemic preconditioning.

Journal: Experimental eye research 20081001

Title: Mary, Mary, quite contrary, how do your beta-cells fail?

Journal: Diabetes 20081001

Title: Chronic antidiabetic sulfonylureas in vivo: reversible effects on mouse pancreatic beta-cells.

Journal: PLoS medicine 20081001

Title: Why treatment fails in type 2 diabetes.

Journal: PLoS medicine 20081001

Title: Calcium uptake in rat liver mitochondria accompanied by activation of ATP-dependent potassium channel.

Journal: Biochemistry. Biokhimiia 20081001

Title: Use of a continuous glucose monitor in the management of inoperable metastatic insulinoma: a case report.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20081001

Title: Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: role of ATP-sensitive potassium channels.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20080915

Title: Diazoxide increases liver and kidney HSP25 and HSP70 after shock and stroke.

Journal: The Journal of surgical research 20080901

Title: Influence of sedentary versus physically active conditions on regulation of plasma renin activity and vasopressin.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080901

Title: Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers.

Journal: Molecular pharmacology 20080901

Title: Stimulation of contractions in human myometrium by serotonin is unmasked by smooth muscle relaxants.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20080901

Title: Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon.

Journal: Diabetologia 20080901

Title: Bringing light to the dark side of insulin: a journey across the blood-brain barrier.

Journal: Diabetes 20080901

Title: Opening of microglial K(ATP) channels inhibits rotenone-induced neuroinflammation.

Journal: Journal of cellular and molecular medicine 20080901

Title: [Hyperinsulinemic hypoglycemia in adults. Case reports and a short review].

Journal: Orvosi hetilap 20080831

Title: The mechanisms of propofol-induced block on ion currents in differentiated H9c2 cardiac cells.

Journal: European journal of pharmacology 20080820

Title: Brief femoral artery ischaemia provides protection against myocardial ischaemia-reperfusion injury in rats: the possible mechanisms.

Journal: Experimental physiology 20080801

Title: Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway.

Journal: Diabetes 20080801

Title: Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: a role for ATP-sensitive potassium channels.

Journal: Epilepsy & behavior : E&B 20080801

Title: Protein kinase D is a key regulator of cardiomyocyte lipoprotein lipase secretion after diabetes.

Journal: Circulation research 20080801

Title: Intramitochondrial signaling: interactions among mitoKATP, PKCepsilon, ROS, and MPT.

Journal: American journal of physiology. Heart and circulatory physiology 20080801

Title: Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant KATP channel mutations.

Journal: The Journal of clinical investigation 20080801

Title: Glucose and glucose transporters regulate lymphatic pump activity through activation of the mitochondrial ATP-sensitive K+ channel.

Journal: The journal of physiological sciences : JPS 20080801

Title: [Bax is involved in K ATP-mediated protection of the hippocampal neurons against hypoxic exposure].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801

Title: Non-islet-cell tumor hypoglycemia and lactic acidosis in a child with congenital HIV and Burkitt's lymphoma.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20080801

Title: Pharmacological prevention of peri-, and post-procedural myocardial injury in percutaneous coronary intervention.

Journal: Current cardiology reviews 20080801

Title: Novel de novo mutation in sulfonylurea receptor 1 presenting as hyperinsulinism in infancy followed by overt diabetes in early adolescence.

Journal: Diabetes 20080701

Title: Bax, Bak and mitochondrial oxidants are involved in hypoxia-reoxygenation-induced apoptosis in human placenta.

Journal: Placenta 20080701

Title: Insulinoma in a third-trimester pregnant woman combined with pre-eclampsia: a case report and review of the diagnostic strategies.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080701

Title: Continuous glucose monitoring in patients with insulinoma.

Journal: Clinical endocrinology 20080601

Title: Dual effect of nitric oxide on ATP-sensitive K+ channels in rat pancreatic beta cells.

Journal: Pflugers Archiv : European journal of physiology 20080601

Title: Persistent hyperinsulinemic hypoglycemia and maturity-onset diabetes of the young due to heterozygous HNF4A mutations.

Journal: Diabetes 20080601

Title: Gene duplications resulting in over expression of glucokinase are not a common cause of hypoglycaemia of infancy in humans.

Journal: Molecular genetics and metabolism 20080601

Title: Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: involvement of the Ca2+ and mitoKATP channels.

Journal: Molecular and cellular biochemistry 20080601

Title: Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart.

Journal: American journal of physiology. Heart and circulatory physiology 20080601

Title: Synthesis and activity on rat aorta rings and rat pancreatic beta-cells of ring-opened analogues of benzopyran-type potassium channel activators.

Journal: Bioorganic & medicinal chemistry 20080601

Title: Is octreotide a risk factor in necrotizing enterocolitis?

Journal: Journal of pediatric surgery 20080601

Title: Water and ion channels: crucial in the initiation and progression of apoptosis in central nervous system?

Journal: Current neuropharmacology 20080601

Title: Neuroprotective effect of diazoxide on brain injury induced by cerebral ischemia/reperfusion during deep hypothermia.

Journal: Journal of the neurological sciences 20080515

Title: Redox properties of the adenoside triphosphate-sensitive K+ channel in brain mitochondria.

Journal: Journal of neuroscience research 20080515

Title: New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (+/-)-cromakalim as tissue-selective pancreatic beta-cell K(ATP) channel openers.

Journal: Bioorganic & medicinal chemistry 20080515

Title: KATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured astrocytes.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080501

Title: Quebrachitol-induced gastroprotection against acute gastric lesions: role of prostaglandins, nitric oxide and K+ ATP channels.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080501

Title: Induction of carbonic anhydrase IX by hypoxia and chemical disruption of oxygen sensing in rat fibroblasts and cardiomyocytes.

Journal: Pflugers Archiv : European journal of physiology 20080501

Title: Non-insulinoma persistent hyperinsulinaemic hypoglycaemia caused by an activating glucokinase mutation: hypoglycaemia unawareness and attacks.

Journal: Clinical endocrinology 20080501

Title: Ovarian steroids stimulate adenosine triphosphate-sensitive potassium (KATP) channel subunit gene expression and confer responsiveness of the gonadotropin-releasing hormone pulse generator to KATP channel modulation.

Journal: Endocrinology 20080501

Title: Effect of diazoxide on flavoprotein oxidation and reactive oxygen species generation during ischemia-reperfusion: a study on Langendorff-perfused rat hearts using optic fibers.

Journal: American journal of physiology. Heart and circulatory physiology 20080501

Title: A Kir6.2 mutation causing severe functional effects in vitro produces neonatal diabetes without the expected neurological complications.

Journal: Diabetologia 20080501

Title: KATP channel openers have opposite effects on mitochondrial respiration under different energetic conditions.

Journal: Journal of cardiovascular pharmacology 20080501

Title: Effect of pressure overload on cardioprotection of mitochondrial KATP channels and GSK-3beta: interaction with the MPT pore.

Journal: American journal of hypertension 20080501

Title: [18F-fluoro-L-DOPA PET-CT imaging combined with genetic analysis for optimal classification and treatment in a child with severe congenital hyperinsulinism].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20080501

Title: Life-threatening hyperkalemia following partial pancreatectomy for neonatal hyperinsulinism.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20080501

Title: Pulmonary hypertension, heart failure and neutropenia due to diazoxide therapy.

Journal: Advances in therapy 20080501

Title: All-trans retinoic acid prevents angiotensin II- and mechanical stretch-induced reactive oxygen species generation and cardiomyocyte apoptosis.

Journal: Journal of cellular physiology 20080401

Title: The paradigm of postconditioning to protect the heart.

Journal: Journal of cellular and molecular medicine 20080401

Title: Involvement of amlodipine, diazoxide, and glibenclamide in development of morphine tolerance in mice.

Journal: The International journal of neuroscience 20080401

Title: Correlates between hyperinsulinism and hyperandrogenemia?

Journal: Fertility and sterility 20080401

Title: Differential increase of mitochondrial matrix volume by sevoflurane in isolated cardiac mitochondria.

Journal: Anesthesia and analgesia 20080401

Title: 20(S)-ginsenoside Rg3 enhances glucose-stimulated insulin secretion and activates AMPK.

Journal: Biological & pharmaceutical bulletin 20080401

Title: Amelioration of oxidative mitochondrial DNA damage and deletion after renal ischemic injury by the KATP channel opener diazoxide.

Journal: American journal of physiology. Renal physiology 20080301

Title: [Protective effect of ischemia and diazoxide preconditioning on postischemic reperfused myocardium and possible mechanism thereof].

Journal: Zhonghua yi xue za zhi 20080226

Title: [Effects of diazoxide on Fas/FasL protein expressions in rat myocardium suffered from long-term hypothermic preservation].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20080225

Title: Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle.

Journal: The Journal of physiology 20080215

Title: Delayed pharmacological pre-conditioning effect of mitochondrial ATP-sensitive potassium channel opener on neurologic injury in a rabbit model of spinal cord ischemia.

Journal: Acta anaesthesiologica Scandinavica 20080201

Title: Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats.

Journal: British journal of pharmacology 20080201

Title: Insulin-releasing properties of the frog skin peptide pseudin-2 and its [Lys18]-substituted analogue.

Journal: Biological chemistry 20080201

Title: Enhanced activation of phospholipase C and insulin secretion from islets incubated in fatty acid-free bovine serum albumin.

Journal: Metabolism: clinical and experimental 20080201

Title: Sildenafil inhibits duodenal contractility via activation of the NO-K+ channel pathway.

Journal: Fundamental & clinical pharmacology 20080201

Title: The spontaneous mechanical activity of the circular smooth muscle of the rabbit colon in vitro.

Journal: Pharmacological research 20080201

Title: Association of malignant insulinoma and type 2 diabetes mellitus: a case report.

Journal: Annales d'endocrinologie 20080201

Title: KATP channel openers: tissue selectivity of original 3-alkylaminopyrido- and 3-alkylaminobenzothiadiazine 1,1-dioxides.

Journal: Biochemical pharmacology 20080115

Title: Glucose induces synchronous mitochondrial calcium oscillations in intact pancreatic islets.

Journal: Cell calcium 20080101

Title: Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats.

Journal: Neuromuscular disorders : NMD 20080101

Title: Acute diabetes moderates trafficking of cardiac lipoprotein lipase through p38 mitogen-activated protein kinase-dependent actin cytoskeleton organization.

Journal: Diabetes 20080101

Title: Importance of timing of magnesium administration in the isolated ischemic-reperfused rat heart: role of K(ATP) channels.

Journal: Physiological research 20080101

Title: Diazoxide prevents abdominal adiposity and fatty liver in obese OLETF rats at prediabetic stage.

Journal: Journal of diabetes and its complications 20080101

Title: [Physiological properties and possible correction of adenosine triphosphate-sensitive potassium channel function].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101

Title: Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms.

Journal: PloS one 20080101

Title: Long-term non-surgical therapy of severe persistent congenital hyperinsulinism with glucagon.

Journal: Hormone research 20080101

Title: Pituitary hypoplasia and growth hormone deficiency in a woman with glycogen storage disease type Ia: a case report.

Journal: Journal of medical case reports 20080101

Title: A pharmacological analysis of the possible role of vasoactive mediators in compensatory coronary blood flow.

Journal: Experimental and clinical cardiology 20080101

Title: Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells.

Journal: PloS one 20080101

Title: Preoperative detection of insulinomas: two case reports.

Journal: Cases journal 20080101

Title: Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion.

Journal: PloS one 20080101

Title: [Diazoxide-induced mitochondrial swelling in the rat myometrium as a consequence of the activation of the mitochondrial ATP-sensitive (K+)-channel].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20080101

Title: Amyloid deposition in transplanted human pancreatic islets: a conceivable cause of their long-term failure.

Journal: Experimental diabetes research 20080101

Title: Episodic confusional state: Due to insulinoma.

Journal: Indian journal of psychiatry 20080101

Title: Hirsutism: clinico-investigative profile of 50 Indian patients.

Journal: Indian journal of dermatology 20080101

Title: Is beta-cell failure in type 2 diabetes mellitus reversible?

Journal: International journal of diabetes in developing countries 20080101

Title: Compound K enhances insulin secretion with beneficial metabolic effects in db/db mice.

Journal: Journal of agricultural and food chemistry 20071226

Title: epsilonPKC phosphorylates the mitochondrial K(+) (ATP) channel during induction of ischemic preconditioning in the rat hippocampus.

Journal: Brain research 20071212

Title: Voltage-gated Ca(2+) influx and insulin secretion in human and mouse beta-cells are impaired by the mitochondrial Na(+)/Ca(2+) exchange inhibitor CGP-37157.

Journal: European journal of pharmacology 20071208

Title: Connexin 43 in ischemic pre- and postconditioning.

Journal: Heart failure reviews 20071201

Title: Nutrient control of insulin secretion in perifused adult pig islets.

Journal: Diabetes & metabolism 20071201

Title: Heterogeneity in disease severity in a family with a novel G68V GCK activating mutation causing persistent hyperinsulinaemic hypoglycaemia of infancy.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20071201

Title: Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20071201

Title: Involvement of glucose and ATP-sensitive potassium (K+) channels on morphine-induced conditioned place preference.

Journal: European journal of pharmacology 20071114

Title: Potassium channel openers accelerate epidermal barrier recovery.

Journal: The British journal of dermatology 20071101

Title: Gliclazide inhibits proliferation but stimulates differentiation of white and brown adipocytes.

Journal: Journal of biochemistry 20071101

Title: From hyperinsulinaemic hypoglycaemia to ketotic hypoglycaemia: the range of glucose abnormalities in patients born with intrauterine growth retardation.

Journal: European journal of pediatrics 20071001

Title: Role of insulin in the hyperandrogenemia of lean women with polycystic ovary syndrome and normal insulin sensitivity.

Journal: Fertility and sterility 20071001

Title: Resveratrol-induced inhibition of insulin secretion from rat pancreatic islets: evidence for pivotal role of metabolic disturbances.

Journal: American journal of physiology. Endocrinology and metabolism 20071001

Title: 5-Hydroxydecanoate inhibits proliferation of hypoxic human pulmonary artery smooth muscle cells by blocking mitochondrial K(ATP) channels.

Journal: Acta pharmacologica Sinica 20071001

Title: Cardioplegia and diazoxide modulate STAT3 activation and DNA binding.

Journal: The Annals of thoracic surgery 20071001

Title: Effective pharmacotherapy against oxidative injury: alternative utility of an ATP-sensitive potassium channel opener.

Journal: Journal of cardiovascular pharmacology 20071001

Title: Ischemic preconditioning: protection against myocardial necrosis and apoptosis.

Journal: Vascular health and risk management 20071001

Title: A review of pioglitazone HCL and glimepiride in the treatment of type 2 diabetes.

Journal: Vascular health and risk management 20071001

Title: Gonadotropin-releasing hormone neurons express K(ATP) channels that are regulated by estrogen and responsive to glucose and metabolic inhibition.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070919

Title: Systemic administration of diazoxide induces delayed preconditioning against transient focal cerebral ischemia in rats.

Journal: Brain research 20070907

Title: The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells.

Journal: FEBS letters 20070904

Title: In vitro evidences for glucosensing capacity and mechanisms in hypothalamus, hindbrain, and Brockmann bodies of rainbow trout.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070901

Title: Congenital hyperinsulinism associated ABCC8 mutations that cause defective trafficking of ATP-sensitive K+ channels: identification and rescue.

Journal: Diabetes 20070901

Title: Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion.

Journal: American journal of physiology. Endocrinology and metabolism 20070901

Title: Effects of washout following indomethacin administration on electrical field stimulation-induced isolated rat gastric fundus strip contractions.

Journal: Journal of gastroenterology and hepatology 20070901

Title: Maintenance of myocyte volume homeostasis during stress by diazoxide is cardioprotective.

Journal: The Annals of thoracic surgery 20070901

Title: Invited commentary.

Journal: The Annals of thoracic surgery 20070901

Title: Diazoxide is protective in the rat retina against ischemic injury induced by bilateral carotid occlusion and glutamate-induced degeneration.

Journal: Neurotoxicity research 20070901

Title: Adenosine and TNF-alpha exert similar inotropic effect on heart cultures, suggesting a cardioprotective mechanism against hypoxia.

Journal: Life sciences 20070816

Title: The actions of a novel potent islet beta-cell specific ATP-sensitive K+ channel opener can be modulated by syntaxin-1A acting on sulfonylurea receptor 1.

Journal: Diabetes 20070801

Title: Activation of alpha1B-adrenoceptors alleviates ischemia/reperfusion injury by limitation of mitochondrial Ca2+ overload in cardiomyocytes.

Journal: Cardiovascular research 20070801

Title: Preconditioning and postconditioning: the essential role of the mitochondrial permeability transition pore.

Journal: Cardiovascular research 20070801

Title: Iptakalim, a vascular ATP-sensitive potassium (KATP) channel opener, closes rat pancreatic beta-cell KATP channels and increases insulin release.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif.

Journal: Diabetologia 20070801

Title: A novel mutation associated with congenital hyperinsulinism.

Journal: American journal of perinatology 20070801

Title: A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial.

Journal: The Australian & New Zealand journal of obstetrics & gynaecology 20070801

Title: The role of mitochondria in protection of the heart by preconditioning.

Journal: Biochimica et biophysica acta 20070801

Title: Development of pulmonary hypertension in an infant treated with diazoxide.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20070801

Title: [Protection mechanisms of ATP-sensitive K channels on hippocampal CA1 neurons during chronic severe hypoxia].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070801

Title: NO mobilizes intracellular Zn2+ via cGMP/PKG signaling pathway and prevents mitochondrial oxidant damage in cardiomyocytes.

Journal: Cardiovascular research 20070715

Title: Lack of effect of short-term diazoxide administration on luteinizing hormone secretion in women with polycystic ovary syndrome.

Journal: Fertility and sterility 20070701

Title: ATP-sensitive potassium channel: a novel target for protection against UV-induced human skin cell damage.

Journal: Journal of cellular physiology 20070701

Title: Transgenic expression of a dominant negative K(ATP) channel subunit in the mouse endothelium: effects on coronary flow and endothelin-1 secretion.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701

Title: Mitochondrial Ca2+-activated K+ channels more efficiently reduce mitochondrial Ca2+ overload in rat ventricular myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20070701

Title: Intermittent activation of bradykinin B2 receptors and mitochondrial KATP channels trigger cardiac postconditioning through redox signaling.

Journal: Cardiovascular research 20070701

Title: No effect of inhibition of insulin secretion by diazoxide on weight loss in hyperinsulinaemic obese subjects during an 8-week weight-loss diet.

Journal: Diabetes, obesity & metabolism 20070701

Title: ATP-sensitive potassium channel in mitochondria of the eukaryotic microorganism Acanthamoeba castellanii.

Journal: The Journal of biological chemistry 20070615

Title: Metabolic and ionic coupling factors in amino acid-stimulated insulin release in pancreatic beta-HC9 cells.

Journal: American journal of physiology. Endocrinology and metabolism 20070601

Title: Regulation of KATP channel subunit gene expression by hyperglycemia in the mediobasal hypothalamus of female rats.

Journal: American journal of physiology. Endocrinology and metabolism 20070601

Title: A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

Journal: PLoS biology 20070601

Title: Expression and function of ATP-dependent potassium channels in late post-infarction remodeling.

Journal: Journal of molecular and cellular cardiology 20070601

Title: Metastatic insulinoma in an adult patient with underlying nesidioblastosis.

Journal: Journal of endocrinological investigation 20070601

Title: Changes in rat myocardium associated with modulation of ischemic tolerance by diazoxide.

Journal: General physiology and biophysics 20070601

Title: Glucose and hippocampal neuronal excitability: role of ATP-sensitive potassium channels.

Journal: Journal of neuroscience research 20070515

Title: ATP-sensitive potassium currents reduce the PGE2-mediated enhancement of excitability in adult rat sensory neurons.

Journal: Brain research 20070511

Title: Effects of propofol on intracellular Ca2+ homeostasis in human astrocytoma cells.

Journal: Brain research 20070511

Title: Virtual screening for novel openers of pancreatic K(ATP) channels.

Journal: Journal of medicinal chemistry 20070503

Title: Oleic acid glucose-independently stimulates glucagon secretion by increasing cytoplasmic Ca2+ via endoplasmic reticulum Ca2+ release and Ca2+ influx in the rat islet alpha-cells.

Journal: Endocrinology 20070501

Title: The role of adenosine triphosphate-regulated potassium channels in propofol-induced beneficial effect on contractile function of hypercholesterolemic isolated rabbit hearts.

Journal: Saudi medical journal 20070501

Title: [Effect of opening of mitochondrial ATP-sensitive K(+) channels on the expression of hypoxia inducible factor-1alpha and cell proliferation in pulmonary arterial smooth muscle cells of rats].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20070425

Title: Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance beta-cell sensitivity.

Journal: Diabetes 20070401

Title: ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia.

Journal: Diabetes 20070401

Title: Mitochondrial ATP-sensitive K+ channels are redox-sensitive pathways that control reactive oxygen species production.

Journal: Free radical biology & medicine 20070401

Title: beta-cell failure in diabetes and preservation by clinical treatment.

Journal: Endocrine reviews 20070401

Title: R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion.

Journal: Nature cell biology 20070401

Title: Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene.

Journal: PLoS medicine 20070401

Title: Drug-induced pulmonary hypertension in newborns: a review.

Journal: Current vascular pharmacology 20070401

Title: Extemporaneous compounding in a sample of New Zealand hospitals: a retrospective survey.

Journal: The New Zealand medical journal 20070323

Title: Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart.

Journal: Circulation research 20070302

Title: Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.

Journal: Molecular endocrinology (Baltimore, Md.) 20070301

Title: Age- and gender-related differences in mitochondrial oxygen consumption and calcium with cardioplegia and diazoxide.

Journal: The Annals of thoracic surgery 20070301

Title: Invited commentary.

Journal: The Annals of thoracic surgery 20070301

Title: Diazoxide, as a postconditioning and delayed preconditioning trigger, increases HSP25 and HSP70 in the central nervous system following combined cerebral stroke and hemorrhagic shock.

Journal: Journal of neurotrauma 20070301

Title: Involvement of ATP-sensitive potassium channels in proliferation and differentiation of rat preadipocytes.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20070225

Title: Pharmacological and molecular characterization of ATP-sensitive K(+) conductances in CART and NPY/AgRP expressing neurons of the hypothalamic arcuate nucleus.

Journal: Neuroscience 20070209

Title: The mitochondrial K(ATP) channel opener BMS-191095 reduces neuronal damage after transient focal cerebral ischemia in rats.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070201

Title: Myocardial preconditioning against ischemia-reperfusion injury is abolished in Zucker obese rats with insulin resistance.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070201

Title: Preconditioning protects endothelium by preventing ET-1-induced activation of NADPH oxidase and xanthine oxidase in post-ischemic heart.

Journal: Journal of molecular and cellular cardiology 20070201

Title: Electrophysiological and pharmacological characterization of the K(ATP) channel involved in the K+-current responses to FSH and adenosine in the follicular cells of Xenopus oocyte.

Journal: The journal of physiological sciences : JPS 20070201

Title: Twelve weeks' treatment with diazoxide without insulin supplementation in Type 2 diabetes is feasible but does not improve insulin secretion.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20070201

Title: The possible mechanisms by which phanoside stimulates insulin secretion from rat islets.

Journal: The Journal of endocrinology 20070201

Title: Downmodulation of mitochondrial F0F1 ATP synthase by diazoxide in cardiac myoblasts: a dual effect of the drug.

Journal: American journal of physiology. Heart and circulatory physiology 20070201

Title: Role of NO/cGMP/KATP pathway in antinociceptive effect of sildenafil in zymosan writhing response in mice.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070201

Title: [Effect of activation of mitochondrial ATP sensitive potassium channel and calcium activated potassium channel on the permeability transition of mitochondria from both normal and ischemic rat brain].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070201

Title: Identification of two types of ATP-sensitive K+ channels in rat ventricular myocytes.

Journal: Life sciences 20070102

Title: Nicorandil opens mitochondrial K(ATP) channels not only directly but also through a NO-PKG-dependent pathway.

Journal: Basic research in cardiology 20070101

Title: Distinct KATP channels mediate the antihypertrophic effects of adenosine receptor activation in neonatal rat ventricular myocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Diazoxide prevents diabetes through inhibiting pancreatic beta-cells from apoptosis via Bcl-2/Bax rate and p38-beta mitogen-activated protein kinase.

Journal: Endocrinology 20070101

Title: Antagonism of the insulinotropic action of first generation imidazolines by openers of K(ATP) channels.

Journal: Biochemical pharmacology 20070101

Title: Diazoxide-induced respiratory inhibition - a putative mitochondrial K(ATP) channel independent mechanism of pharmacological preconditioning.

Journal: Molecular and cellular biochemistry 20070101

Title: Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic beta-cells.

Journal: The Journal of endocrinology 20070101

Title: Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: a case report.

Journal: BMC cancer 20070101

Title: Involvement of alpha-receptors and potassium channels in the mechanism of action of sildenafil citrate.

Journal: International journal of impotence research 20070101

Title: Effect of diazoxide and Ca2+ on rat heart mitochondria loaded with Na+.

Journal: Doklady. Biochemistry and biophysics 20070101

Title: Involvement of SH-groups during interaction of diazoxide with the inner membrane of rat heart mitochondria.

Journal: Doklady. Biochemistry and biophysics 20070101

Title: Rapid intraoperative insulin assay: a novel method to differentiate insulinoma from nesidioblastosis in the pediatric patient.

Journal: Annals of surgical innovation and research 20070101

Title: NFU-Enabled FASTA: moving bioinformatics applications onto wide area networks.

Journal: Source code for biology and medicine 20070101

Title: Serofendic acid, a substance extracted from fetal calf serum, as a novel drug for cardioprotection.

Journal: Cardiovascular drug reviews 20070101

Title: Pitfalls in diagnosing a small cystic insulinoma: a case report.

Journal: Journal of medical case reports 20070101

Title: Pharmacological preconditioning with diazoxide slows energy metabolism during sustained ischemia.

Journal: Experimental and clinical cardiology 20070101

Title: New benzopyran-based openers of the mitochondrial ATP-sensitive potassium channel with potent anti-ischemic properties.

Journal: Journal of medicinal chemistry 20061228

Title: Glucose and insulin synergistically activate phosphatidylinositol 3-kinase to trigger oscillations of phosphatidylinositol 3,4,5-trisphosphate in beta-cells.

Journal: The Journal of biological chemistry 20061222

Title: Influence of ATP-dependent K+ channels on nicotine-induced inhibition of withdrawal in morphine-dependent mice.

Journal: European journal of pharmacology 20061215

Title: Diazoxide acts more as a PKC-epsilon activator, and indirectly activates the mitochondrial K(ATP) channel conferring cardioprotection against hypoxic injury.

Journal: British journal of pharmacology 20061201

Title: The atypical antipsychotic clozapine impairs insulin secretion by inhibiting glucose metabolism and distal steps in rat pancreatic islets.

Journal: Diabetologia 20061201

Title: Nutrient control of insulin secretion in isolated normal human islets.

Journal: Diabetes 20061201

Title: Contribution of calcium influx in mediating glucose-stimulated oxygen consumption in pancreatic islets.

Journal: Diabetes 20061201

Title: Ischemic preconditioning prevents endothelial dysfunction, P-selectin expression, and neutrophil adhesion by preventing endothelin and O2- generation in the post-ischemic guinea-pig heart.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201

Title: Mosaic Turner syndrome and hyperinsulinaemic hypoglycaemia.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20061201

Title: Hypoglycemia in the neonate.

Journal: Pediatric endocrinology reviews : PER 20061201

Title: Diabetes and hypoglycaemia in young children and mutations in the Kir6.2 subunit of the potassium channel: therapeutic consequences.

Journal: Diabetes & metabolism 20061201

Title: Stimulus-secretion coupling of hypotonicity-induced insulin release in BRIN-BD11 cells.

Journal: Endocrine 20061201

Title: K+ channels involved in contractility of rabbit small intestine.

Journal: Journal of physiology and biochemistry 20061201

Title: Influence of ATP-sensitive potassium channels on lithium state-dependent memory of passive avoidance in mice.

Journal: European journal of pharmacology 20061121

Title: Iptakalim protects PC12 cell against H2O2-induced oxidative injury via opening mitochondrial ATP-sensitive potassium channel.

Journal: Biochemical and biophysical research communications 20061117

Title: Opening mitoKATP increases superoxide generation from complex I of the electron transport chain.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: Mechanism of reactive oxygen species generation after opening of mitochondrial KATP channels.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation.

Journal: Cardiovascular research 20061101

Title: FCCP is cardioprotective at concentrations that cause mitochondrial oxidation without detectable depolarisation.

Journal: Cardiovascular research 20061101

Title: Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes.

Journal: British journal of pharmacology 20061101

Title: Clinical features and morphological characterization of 10 patients with noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS).

Journal: Clinical endocrinology 20061101

Title: Prolonged hyperinsulinaemic hypoglycaemia in newborns with intrauterine growth retardation.

Journal: Archives of disease in childhood. Fetal and neonatal edition 20061101

Title: European Academy of Paediatrics, Barcelona, Spain, October 7-10, 2006. Abstracts.

Journal: European journal of pediatrics 20061101

Title: [The effect of mitochondrial membrane potential on changes of reactive oxygen species and on proliferation of hypoxic human pulmonary arterial smooth muscle cells].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20061101

Title: Diazoxide-induced cardioprotection via DeltaPsim loss depending on timing of application.

Journal: Life sciences 20061012

Title: LPS from Escherichia coli protects against indomethacin-induced gastropathy in rats--role of ATP-sensitive potassium channels.

Journal: European journal of pharmacology 20061010

Title: First molecular evidence that inositol trisphosphate signaling contributes to infarct size reduction with preconditioning.

Journal: American journal of physiology. Heart and circulatory physiology 20061001

Title: Iptakalim modulates ATP-sensitive K(+) channels in dopamine neurons from rat substantia nigra pars compacta.

Journal: The Journal of pharmacology and experimental therapeutics 20061001

Title: C16:0 sulfatide inhibits insulin secretion in rat beta-cells by reducing the sensitivity of KATP channels to ATP inhibition.

Journal: Diabetes 20061001

Title: Hyperlipidemic mice present enhanced catabolism and higher mitochondrial ATP-sensitive K+ channel activity.

Journal: Gastroenterology 20061001

Title: Pancreatic islets from hypothalamic obese rats maintain K+ATP channel-dependent but not -independent pathways on glucose-induced insulin release process.

Journal: Endocrine 20061001

Title: Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways.

Journal: Circulation research 20060929

Title: Diazoxide protects against methylmalonate-induced neuronal toxicity.

Journal: Experimental neurology 20060901

Title: Diazoxide preconditioning alleviates apoptosis of hippocampal neurons induced by anoxia-reoxygenation in vitro through up-regulation of Bcl-2/Bax protein ratio.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20060825

Title: K+-independent actions of diazoxide question the role of inner membrane KATP channels in mitochondrial cytoprotective signaling.

Journal: The Journal of biological chemistry 20060818

Title: The diagnosis of ectopic focal hyperinsulinism of infancy with [18F]-dopa positron emission tomography.

Journal: The Journal of clinical endocrinology and metabolism 20060801

Title: K+-ATP-channel-related protein complexes: potential transducers in the regulation of epithelial tight junction permeability.

Journal: Journal of cell science 20060801

Title: Total cellular calcium and magnesium content of cultured human peripheral blood mononuclear cells following exposure to antidiabetic drugs.

Journal: Acta diabetologica 20060801

Title: Paradoxical stimulation of glucagon secretion by high glucose concentrations.

Journal: Diabetes 20060801

Title: First phase of glucose-stimulated insulin secretion from MIN 6 cells does not always require extracellular calcium influx.

Journal: Journal of pharmacological sciences 20060801

Title: Hypertrichosis lanuginosa acquisita associated with autoimmune hepatitis.

Journal: The Journal of dermatology 20060801

Title: Recurrent hyperinsulinemic hypoglycemia caused by an insulin-secreting insulinoma.

Journal: Nature clinical practice. Endocrinology & metabolism 20060801

Title: [Role of gap junction in ischemic preconditioning].

Journal: Zhonghua xin xue guan bing za zhi 20060801

Title: Hyperinsulinism in infancy--genetic aspects.

Journal: Pediatric endocrinology reviews : PER 20060801

Title: The mechanism by which the mitochondrial ATP-sensitive K+ channel opening and H2O2 inhibit the mitochondrial permeability transition.

Journal: The Journal of biological chemistry 20060728

Title: Design, synthesis, and pharmacological evaluation of R/S-3,4-dihydro-2,2-dimethyl- 6-halo-4-(phenylaminocarbonylamino)-2H-1-benzopyrans: toward tissue-selective pancreatic beta-cell KATP channel openers structurally related to (+/-)-cromakalim.

Journal: Journal of medicinal chemistry 20060727

Title: It is AMPA receptor, not kainate receptor, that contributes to the NBQX-induced antinociception in the spinal cord of rats.

Journal: Brain research 20060719

Title: Drugs for treatment of very high blood pressure during pregnancy.

Journal: The Cochrane database of systematic reviews 20060719

Title: New 3-alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-dioxide derivatives activate ATP-sensitive potassium channels of pancreatic beta cells.

Journal: Journal of medicinal chemistry 20060713

Title: The neuroprotection conferred by activating the mitochondrial ATP-sensitive K+ channel is mediated by inhibiting the mitochondrial permeability transition pore.

Journal: Neuroscience letters 20060710

Title: Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection.

Journal: Circulation research 20060707

Title: Regulation of plasma vasopressin and renin activity in conscious hindlimb-unloaded rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060701

Title: A novel approach to assess insulin sensitivity reveals no increased insulin sensitivity in mice with a dominant-negative mutant hepatocyte nuclear factor-1alpha.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060701

Title: Intravenous 6-hydroxydopamine attenuates vasopressin and oxytocin secretion stimulated by hemorrhage and hypotension but not hyperosmolality in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060701

Title: No loss of cardioprotection by postconditioning in connexin 43-deficient mice.

Journal: Basic research in cardiology 20060701

Title: Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis.

Journal: Diabetologia 20060701

Title: Age- and gender-related differences in ischemia/reperfusion injury and cardioprotection: effects of diazoxide.

Journal: The Annals of thoracic surgery 20060701

Title: ATP-sensitive potassium channels mediate the anti-ischemic properties of ischemic and pharmacologic preconditioning in rat random-pattern skin flap.

Journal: Annals of plastic surgery 20060701

Title: [Effect of opening of mitochondrial ATP-sensitive K⁺ channel on the distribution of cytochrome C and on proliferation of human pulmonary arterial smooth muscle cells in hypoxia].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20060625

Title: Selective inhibition of pinacidil effects by estrogen in guinea pig heart.

Journal: International journal of cardiology 20060607

Title: Diazoxide preconditioning plus subsequent hypothermia increased resistance of rat cultured hippocampal neurons against hypoxia-reoxygenation injury.

Journal: Chinese medical journal 20060605

Title: Levosimendan protects against experimental endotoxemic acute renal failure.

Journal: American journal of physiology. Renal physiology 20060601

Title: Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets.

Journal: Endocrinology 20060601

Title: Cardiac protection by mitoKATP channels is dependent on Akt translocation from cytosol to mitochondria during late preconditioning.

Journal: American journal of physiology. Heart and circulatory physiology 20060601

Title: EUS-guided alcohol ablation of an insulinoma.

Journal: Gastrointestinal endoscopy 20060601

Title: The effect of pre- and posttreatment with diazoxide on the early phase of chronic cerebral hypoperfusion in the rat.

Journal: Brain research 20060504

Title: Serofendic acid, a novel substance extracted from fetal calf serum, protects against oxidative stress in neonatal rat cardiac myocytes.

Journal: Journal of the American College of Cardiology 20060502

Title: Nitric oxide-cGMP-protein kinase G signaling pathway induces anoxic preconditioning through activation of ATP-sensitive K+ channels in rat hearts.

Journal: American journal of physiology. Heart and circulatory physiology 20060501

Title: Characterization of human cardiac mitochondrial ATP-sensitive potassium channel and its regulation by phorbol ester in vitro.

Journal: American journal of physiology. Heart and circulatory physiology 20060501

Title: Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression.

Journal: Neuroscience letters 20060501

Title: Combined modulation of the mitochondrial ATP-dependent potassium channel and the permeability transition pore causes prolongation of the biphasic calcium dynamics.

Journal: Cell calcium 20060501

Title: MitoKATP channel activation suppresses gap junction permeability in the ischemic myocardium by an ERK-dependent mechanism.

Journal: Cardiovascular research 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Antihypertensive drugs clonidine, diazoxide, hydralazine and furosemide regulate the production of cytokines by placentas and peripheral blood mononuclear cells in normal pregnancy.

Journal: Journal of hypertension 20060501

Title: Noninvasive assessment of brain injury in a canine model of hypothermic circulatory arrest using magnetic resonance spectroscopy.

Journal: The Annals of thoracic surgery 20060501

Title: Preservation of mitochondrial structure and function after cardioplegic arrest in the neonate using a selective mitochondrial KATP channel opener.

Journal: The Annals of thoracic surgery 20060501

Title: A mysterious case of normalising blood sugar: insulinoma in a long-standing diabetic patient.

Journal: Age and ageing 20060501

Title: Mitochondrial potassium ATP channels and retinal ischemic preconditioning.

Journal: Investigative ophthalmology & visual science 20060501

Title: L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter.

Journal: Diabetes 20060501

Title: The mitochondrial K-ATP channel opener, diazoxide, prevents ischemia-reperfusion injury in the rabbit spinal cord.

Journal: The American journal of pathology 20060501

Title: Diazoxide provides maximal KATP channels independent protection if present throughout hypoxia.

Journal: The Annals of thoracic surgery 20060401

Title: Invited commentary.

Journal: The Annals of thoracic surgery 20060401

Title: Data and animal management software for large-scale phenotype screening.

Journal: Mammalian genome : official journal of the International Mammalian Genome Society 20060401

Title: Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta-cells.

Journal: The Journal of endocrinology 20060401

Title: MitoK(ATP)-dependent changes in mitochondrial volume and in complex II activity during ischemic and pharmacological preconditioning of Langendorff-perfused rat heart.

Journal: Journal of bioenergetics and biomembranes 20060401

Title: Different effects of optical isomers of the 5-HT1A receptor antagonist pyrapyridolol against postischemic guinea-pig myocardial dysfunction and apoptosis through the mitochondrial permeability transition pore.

Journal: European journal of pharmacology 20060318

Title: Protein kinase G-induced activation of K(ATP) channels reduces contractility of human prostate tissue.

Journal: The Prostate 20060301

Title: Changes in membrane cholesterol of pituitary tumor (GH3) cells regulate the activity of large-conductance Ca2+-activated K+ channels.

Journal: The Chinese journal of physiology 20060227

Title: Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs.

Journal: European journal of pharmacology 20060217

Title: The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin.

Journal: European journal of pharmacology 20060215

Title: The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells.

Journal: Neuroscience letters 20060213

Title: Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets.

Journal: The Journal of biological chemistry 20060210

Title: A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channels.

Journal: The Journal of biological chemistry 20060203

Title: Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats.

Journal: The international journal of neuropsychopharmacology 20060201

Title: Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium.

Journal: Cardiovascular research 20060201

Title: Ischemic preconditioning requires increases in reactive oxygen release independent of mitochondrial K+ channel activity.

Journal: Free radical biology & medicine 20060201

Title: Clinical features and insulin regulation in infants with a syndrome of prolonged neonatal hyperinsulinism.

Journal: The Journal of pediatrics 20060201

Title: P-1075 exerts diverse modulatory effects on mitochondrial ATP-sensitive K+ channels in rabbit ventricular myocytes.

Journal: Journal of cardiovascular pharmacology 20060201

Title: A rare case of adult-onset nesidioblastosis treated successfully with diazoxide.

Journal: Endocrine journal 20060201

Title: [The effects of diazoxide on myocardium function and the expressions of ERK and JNK in isolated spontaneous hypertension rat hearts].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060201

Title: KATP channels in mouse spermatogenic cells and sperm, and their role in capacitation.

Journal: Developmental biology 20060115

Title: Acute and chronic effects of glucose and carbachol on insulin secretion and phospholipase C activation: studies with diazoxide and atropine.

Journal: American journal of physiology. Endocrinology and metabolism 20060101

Title: Initiation of remote microvascular preconditioning requires K(ATP) channel activity.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Non-beating HL-1 cells for confocal microscopy: application to mitochondrial functions during cardiac preconditioning.

Journal: Progress in biophysics and molecular biology 20060101

Title: The direct physiological effects of mitoK(ATP) opening on heart mitochondria.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Role of the sarcolemmal adenosine triphosphate-sensitive potassium channel in hyperkalemic cardioplegia-induced myocyte swelling and reduced contractility.

Journal: The Annals of thoracic surgery 20060101

Title: Hyperkalemic cardioplegia-induced myocyte swelling and contractile dysfunction: prevention by diazoxide.

Journal: The Annals of thoracic surgery 20060101

Title: Effect of phosphodiesterase 5 inhibitor on alteration in vascular smooth muscle sensitivity and renal function in rats with liver cirrhosis.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Effects of sulfonylureas on mitochondrial ATP-sensitive K+ channels in cardiac myocytes: implications for sulfonylurea controversy.

Journal: Diabetes/metabolism research and reviews 20060101

Title: Possible role of potassium channel, big K in etiology of schizophrenia.

Journal: Medical hypotheses 20060101

Title: Towards selective Kir6.2/SUR1 potassium channel openers, medicinal chemistry and therapeutic perspectives.

Journal: Current medicinal chemistry 20060101

Title: Complete clinical remission and disappearance of liver metastases after treatment with somatostatin analogue in a 40-year-old woman with a malignant insulinoma positive for somatostatin receptors type 2.

Journal: Hormone research 20060101

Title: Ischemic preconditioning: a novel target for neuroprotective therapy.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20060101

Title: [Pitfalls in the diagnosis of congenital hyperinsulinism: a case report and review of the literature].

Journal: Klinische Padiatrie 20060101

Title: Comparative proteomics analysis of differentially expressed phosphoproteins in adult rat ventricular myocytes subjected to diazoxide preconditioning.

Journal: Drug metabolism and drug interactions 20060101

Title: [The influence of the fluorine-containing activators of mitochondrial adenosine triphosphate sensitive potassium channels on the oxidative phosphorilation].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101

Title: Study of the mechanism of action of diazoxide on rat heart mitochondria under calcium loading.

Journal: Doklady. Biochemistry and biophysics 20060101

Title: Cardioprotective effects of diazoxide on myocardial ischemia/reperfusion injury in rats.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101

Title: A role of opening of mitochondrial ATP-sensitive potassium channels in the infarct size-limiting effect of ischemic preconditioning via activation of protein kinase C in the canine heart.

Journal: Biochemical and biophysical research communications 20051223

Title: Costello syndrome and hyperinsulinemic hypoglycemia.

Journal: American journal of medical genetics. Part A 20051215

Title: [Diazoxide preconditioning combined with subsequent hypothermia alleviates anoxia-re-oxygenation injury: experiment with rat hippocampal neurons].

Journal: Zhonghua yi xue za zhi 20051207

Title: Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms.

Journal: The Journal of physiology 20051201

Title: Diazoxide attenuates insulin secretion and hepatic lipogenesis in zucker diabetic fatty rats.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20051201

Title: Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells.

Journal: Endocrinology 20051101

Title: Late preconditioning with isoflurane in cultured rat cortical neurones.

Journal: British journal of anaesthesia 20051101

Title: Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia.

Journal: Diabetologia 20051101

Title: [Congenital hyperinsulinism in newborn and infant].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20051101

Title: Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats.

Journal: Diabetes 20051101

Title: Synaptic activity becomes excitotoxic in neurons exposed to elevated levels of platelet-activating factor.

Journal: The Journal of clinical investigation 20051101

Title: Persistent hyperinsulinaemic hypoglycaemia of infancy: 15 years' experience at the Royal Children's Hospital (RCH), Melbourne.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20051101

Title: Characterization of K(ATP)-channels in rat basilar and middle cerebral arteries: studies of vasomotor responses and mRNA expression.

Journal: European journal of pharmacology 20051031

Title: Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion.

Journal: Neuroscience letters 20051028

Title: Antidiabetic activity and toxicity of Zizyphus spina-christi leaves.

Journal: Journal of ethnopharmacology 20051003

Title: Lack of manifestations of diazoxide/5-hydroxydecanoate-sensitive KATP channel in rat brain nonsynaptosomal mitochondria.

Journal: The Journal of physiology 20051001

Title: Transgenic overexpression of SUR1 in the heart suppresses sarcolemmal K(ATP).

Journal: Journal of molecular and cellular cardiology 20051001

Title: Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca2+ in insulin-secreting beta-cells.

Journal: Journal of cell science 20051001

Title: Sulphonylurea sensitivity and enriched expression implicate inward rectifier K+ channels in Drosophila melanogaster renal function.

Journal: The Journal of experimental biology 20051001

Title: Multiple treatment approach to limit cardiac ischemia-reperfusion injury.

Journal: The Annals of thoracic surgery 20051001

Title: Invited commentary.

Journal: The Annals of thoracic surgery 20051001

Title: Serum glucagon counterregulatory hormonal response to hypoglycemia is blunted in congenital hyperinsulinism.

Journal: Diabetes 20051001

Title: [Effects of iptakalim on intracellular calcium concentrations, PKA and PKC activities in rat tail artery smooth muscle cells].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051001

Title: Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice.

Journal: Circulation research 20050916

Title: Sulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility.

Journal: Journal of cell science 20050915

Title: Effect of indomethacin on electrical field stimulation-induced contractions of isolated transverse and longitudinal rat gastric fundus strips.

Journal: World journal of gastroenterology 20050914

Title: Different actions of cardioprotective agents on mitochondrial Ca2+ regulation in a Ca2+ paradox-induced Ca2+ overload.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20050901

Title: Gestational change of K+ channel opener effect is correlated with the expression of uterine KATP channel subunits.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20050901

Title: Myocyte volume and function in response to osmotic stress: observations in the presence of an adenosine triphosphate-sensitive potassium channel opener.

Journal: Circulation 20050830

Title: Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks.

Journal: Circulation research 20050819

Title: Protein kinase G transmits the cardioprotective signal from cytosol to mitochondria.

Journal: Circulation research 20050819

Title: Identification of N-arachidonylglycine, U18666A, and 4-androstene-3,17-dione as novel insulin Secretagogues.

Journal: Biochemical and biophysical research communications 20050805

Title: Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20050801

Title: Integrated pharmacological preconditioning and memory of cardioprotection: role of protein kinase C and phosphatidylinositol 3-kinase.

Journal: American journal of physiology. Heart and circulatory physiology 20050801

Title: Metamizol acts as an ATP sensitive potassium channel opener to inhibit the contracting response induced by angiotensin II but not to norepinephrine in rat thoracic aorta smooth muscle.

Journal: Vascular pharmacology 20050801

Title: Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans.

Journal: Environmental health perspectives 20050801

Title: MitoKATP-channel opener protects against neuronal death in rat venous ischemia.

Journal: Neurosurgery 20050801

Title: Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria.

Journal: Brain research bulletin 20050730

Title: 3-Alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel openers: effect of 6,7-disubstitution on potency and tissue selectivity.

Journal: Journal of medicinal chemistry 20050728

Title: Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability.

Journal: Brain research 20050727

Title: Malignant insulinoma: spectrum of unusual clinical features.

Journal: Cancer 20050715

Title: Adenosine and ATP-sensitive potassium channels modulate dopamine release in the anoxic turtle (Trachemys scripta) striatum.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050701

Title: Diazoxide preserves hypercapnia-induced arteriolar vasodilation after global cerebral ischemia in piglets.

Journal: American journal of physiology. Heart and circulatory physiology 20050701

Title: K(ATP) channels and preconditioning: a re-examination of the role of mitochondrial K(ATP) channels and an overview of alternative mechanisms.

Journal: Journal of molecular and cellular cardiology 20050701

Title: Mitochondrial K(ATP) channels in cell survival and death.

Journal: Journal of molecular and cellular cardiology 20050701

Title: Cardioprotective effects of K ATP channel activation during hypoxia in goldfish Carassius auratus.

Journal: The Journal of experimental biology 20050701

Title: Probing of specific binding of synthetic sulfonylurea with the insulinoma cell line MIN6.

Journal: Journal of biochemistry 20050701

Title: [Protective effect of mitochondrial ATP-sensitive potassium channel opener on rat heart during hypothermic preservation].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20050701

Title: Role of adenosine A1 and A3 receptors in regulation of cardiomyocyte homeostasis after mitochondrial respiratory chain injury.

Journal: American journal of physiology. Heart and circulatory physiology 20050601

Title: Ketotic hypoglycaemia in children with diazoxide responsive hyperinsulinism of infancy.

Journal: European journal of pediatrics 20050601

Title: SUR, ABC proteins targeted by KATP channel openers.

Journal: Journal of molecular and cellular cardiology 20050601

Title: Mitochondria and ischemia/reperfusion injury.

Journal: Annals of the New York Academy of Sciences 20050601

Title: Effect on K(ATP) channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides.

Journal: Journal of medicinal chemistry 20050519

Title: Reactive oxygen species mediate the neuroprotection conferred by a mitochondrial ATP-sensitive potassium channel opener during ischemia in the rat hippocampal slice.

Journal: Brain research 20050503

Title: Prostacyclin attenuates oxidative damage of myocytes by opening mitochondrial ATP-sensitive K+ channels via the EP3 receptor.

Journal: American journal of physiology. Heart and circulatory physiology 20050501

Title: Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats.

Journal: Journal of neuroscience research 20050501

Title: Diazoxide-mediated insulin suppression in obese men: a dose-response study.

Journal: Diabetes, obesity & metabolism 20050501

Title: Effects of KATP channel modulation on myocardial glycogen content, lactate, and amino acids in nonischemic and ischemic rat hearts.

Journal: Journal of cardiovascular pharmacology 20050501

Title: The ATP-sensitive potassium channel blocker glibenclamide prevents renal ischemia/reperfusion injury in rats.

Journal: Kidney international 20050501

Title: 150-kD oxygen-regulated protein is an essential factor for insulin release.

Journal: Pancreas 20050501

Title: Alterations in net glucose uptake and in the pancreatic B-cell GLUT2 transporter induced by diazoxide and by secretory stimuli.

Journal: The Journal of endocrinology 20050501

Title: Hyperinsulinism of infancy associated with a novel splice site mutation in the SCHAD gene.

Journal: The Journal of pediatrics 20050501

Title: Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427

Title: Evidence that insulin secretion influences SNAP-25 through proteasomal activation.

Journal: Biochemical and biophysical research communications 20050415

Title: mitoKATP channel activation in the postanoxic developing heart protects E-C coupling via NO-, ROS-, and PKC-dependent pathways.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: Peptide blockers of PKG inhibit ROS generation by acetylcholine and bradykinin in cardiomyocytes but fail to block protection in the whole heart.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: Are one or two dangerous? Sulfonylurea exposure in toddlers.

Journal: The Journal of emergency medicine 20050401

Title: Genotypes of the pancreatic beta-cell K-ATP channel and clinical phenotypes of Japanese patients with persistent hyperinsulinaemic hypoglycaemia of infancy.

Journal: Clinical endocrinology 20050401

Title: Novel and established potassium channel openers stimulate hair growth in vitro: implications for their modes of action in hair follicles.

Journal: The Journal of investigative dermatology 20050401

Title: Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.

Journal: European journal of endocrinology 20050401

Title: Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugs.

Journal: Journal of molecular endocrinology 20050401

Title: Mitochondrial ATP-sensitive K+ channels prevent oxidative stress, permeability transition and cell death.

Journal: Journal of bioenergetics and biomembranes 20050401

Title: Protective effects of sarpogrelate, a 5-HT2A antagonist, against postischemic myocardial dysfunction in guinea-pig hearts.

Journal: Molecular and cellular biochemistry 20050401

Title: Remote preconditioning reduces ischemic injury in the explanted heart by a KATP channel-dependent mechanism.

Journal: American journal of physiology. Heart and circulatory physiology 20050301

Title: Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide.

Journal: Hypertension (Dallas, Tex. : 1979) 20050301

Title: Loss of the decrement in intraislet insulin plausibly explains loss of the glucagon response to hypoglycemia in insulin-deficient diabetes: documentation of the intraislet insulin hypothesis in humans.

Journal: Diabetes 20050301

Title: Differential effects of insulin and dietary amino acids on muscle protein synthesis in adult and old rats.

Journal: The Journal of physiology 20050215

Title: Calcium-activated potassium channel triggers cardioprotection of ischemic preconditioning.

Journal: The Journal of pharmacology and experimental therapeutics 20050201

Title: Genotype-phenotype correlations in children with congenital hyperinsulinism due to recessive mutations of the adenosine triphosphate-sensitive potassium channel genes.

Journal: The Journal of clinical endocrinology and metabolism 20050201

Title: Mitochondrial K(ATP) channels in respiratory neurons and their role in the hypoxic facilitation of rhythmic activity.

Journal: Brain research 20050201

Title: Diagnostic difficulties in long-standing insulinoma with near-normal plasma insulin levels.

Journal: Journal of endocrinological investigation 20050201

Title: 4,6-Disubstituted 2,2-dimethylchromans structurally related to the K(ATP) channel opener cromakalim: design, synthesis, and effect on insulin release and vascular tone.

Journal: Journal of medicinal chemistry 20050127

Title: Diazoxide and dimethyl sulphoxide alleviate experimental cerebral hypoperfusion-induced white matter injury in the rat brain.

Journal: Neuroscience letters 20050120

Title: Mitochondrial Ca2+-activated K+ channels in cardiac myocytes: a mechanism of the cardioprotective effect and modulation by protein kinase A.

Journal: Circulation 20050118

Title: Effect of mitochondrial KATP channel on voltage-gated K+ channel in 24 hour-hypoxic human pulmonary artery smooth muscle cells.

Journal: Chinese medical journal 20050105

Title: Activation of ATP-sensitive potassium channels prevents the cleavage of cytosolic mu-calpain and abrogates the elevation of nuclear c-Fos and c-Jun expressions after hypoxic-ischemia in neonatal rat brain.

Journal: Brain research. Molecular brain research 20050105

Title: Synthesis and pharmacological evaluation of 4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide and N-(2-cyanomethylsulfonylphenyl)acylamide derivatives as potential activators of ATP sensitive potassium channels.

Journal: Bioorganic & medicinal chemistry 20050103

Title: Mechanism, temporal patterns, and magnitudes of the metabolic responses to the KATP channel agonist diazoxide.

Journal: American journal of physiology. Endocrinology and metabolism 20050101

Title: Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide.

Journal: Biochemical pharmacology 20050101

Title: Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature.

Journal: BMC physiology 20050101

Title: Contemporary strategies in the diagnosis and management of neonatal hyperinsulinaemic hypoglycaemia.

Journal: Early human development 20050101

Title: Hyperinsulinism in tyrosinaemia type I.

Journal: Journal of inherited metabolic disease 20050101

Title: Diazoxide ameliorates microcirculatory disturbances through PKC-dependent pathway in I/R-injured rat cremaster muscles.

Journal: Journal of biomedical science 20050101

Title: Fatality after deliberate ingestion of the pesticide rotenone: a case report.

Journal: Critical care (London, England) 20050101

Title: Severe hyperinsulinaemic hypoglycaemia in a baby born to a mother taking oral ritodrine therapy for preterm labour.

Journal: Hormone research 20050101

Title: Effect of the degree of ischaemic injury and reoxygenation time on the type of myocardial cell death in man: role of caspases.

Journal: BMC physiology 20050101

Title: Effects of diazoxide treatments on electrophysiologyic properties in guinea pig papillary muscles undergoing ischemia/reperfusion.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

Title: ATP-sensitive potassium channel (KATP channel) expression in the normal canine pancreas and in canine insulinomas.

Journal: BMC veterinary research 20050101

Title: Neuroprotective effect of KR-31378, a novel potassium channel activator, on spinal cord ischemic injury in rabbits.

Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20050101

Title: Bench-to-bedside review: Antidotal treatment of sulfonylurea-induced hypoglycaemia with octreotide.

Journal: Critical care (London, England) 20050101

Title: Activation of Mitochondrial ATP-Sensitive Potassium Channel Contributes to Protective Effect in Prolonged Myocardial Preservation.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101

Title: Differing effects of cyclosporin a on swelling amplitude and time constant of mitochondria from normal and ischemic rat brain.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101

Title: Mitochondrial permeability transition dynamics: an indicator of mitochondrial potassium channel opener.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101

Title: Ischemic preconditioning and diazoxide limit mitochondrial Ca overload during ischemia/reperfusion: Role of reactive oxygen species.

Journal: Experimental and clinical cardiology 20050101

Title: 2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide activates Kir6.2/SUR1 K(ATP) channels.

Journal: Bioorganic & medicinal chemistry letters 20041206

Title: Short-term intermittent exposure to diazoxide improves functional performance of beta-cells in a high-glucose environment.

Journal: American journal of physiology. Endocrinology and metabolism 20041201

Title: Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide.

Journal: Endocrinology 20041201

Title: Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators.

Journal: Diabetes 20041201

Title: Signaling elements involved in the metabolic regulation of mTOR by nutrients, incretins, and growth factors in islets.

Journal: Diabetes 20041201

Title: P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism.

Journal: Diabetes 20041201

Title: Massive augmentation of stimulated insulin secretion induced by fatty acid-free BSA in rat pancreatic islets.

Journal: Diabetes 20041201

Title: Myocardial impairment in chronic hypoxia is abolished by short aeration episodes: involvement of K+ATP channels.

Journal: Experimental biology and medicine (Maywood, N.J.) 20041201

Title: Bimodal role of conventional protein kinase C in insulin secretion from rat pancreatic beta cells.

Journal: The Journal of physiology 20041115

Title: Testosterone induces cytoprotection by activating ATP-sensitive K+ channels in the cardiac mitochondrial inner membrane.

Journal: Circulation 20041109

Title: Diazoxide-mediated preconditioning against apoptosis involves activation of cAMP-response element-binding protein (CREB) and NFkappaB.

Journal: The Journal of biological chemistry 20041105

Title: Quinolizidine alkaloids isolated from Lupinus species enhance insulin secretion.

Journal: European journal of pharmacology 20041103

Title: Opening of Ca2+-activated K+ channels triggers early and delayed preconditioning against I/R injury independent of NOS in mice.

Journal: American journal of physiology. Heart and circulatory physiology 20041101

Title: Opening of mitochondrial KATP channels enhances cardioprotection through the modulation of mitochondrial matrix volume, calcium accumulation, and respiration.

Journal: American journal of physiology. Heart and circulatory physiology 20041101

Title: PKC-epsilon is upstream and PKC-alpha is downstream of mitoKATP channels in the signal transduction pathway of ischemic preconditioning of human myocardium.

Journal: American journal of physiology. Cell physiology 20041101

Title: Fluctuations in mitochondrial membrane potential in single isolated brain mitochondria: modulation by adenine nucleotides and Ca2+.

Journal: Biophysical journal 20041101

Title: Effect of diazoxide on regulation of vesicular and plasma membrane GABA transporter genes and proteins in hippocampus of rats subjected to picrotoxin-induced kindling.

Journal: Neuroscience research 20041101

Title: A new ATP-sensitive K+ channel-independent mechanism is involved in glucose-excited neurons of mouse arcuate nucleus.

Journal: Diabetes 20041101

Title: Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels and elevation of cytoplasmic calcium.

Journal: Diabetes 20041101

Title: Palmitoyl lysophosphatidylcholine mediated mobilization of LPL to the coronary luminal surface requires PKC activation.

Journal: Journal of molecular and cellular cardiology 20041101

Title: Inhibition of phenylephrine induced hypertrophy in rat neonatal cardiomyocytes by the mitochondrial KATP channel opener diazoxide.

Journal: Journal of molecular and cellular cardiology 20041101

Title: Selective arterial calcium stimulation and hepatic venous sampling in the evaluation of hyperinsulinemic hypoglycemia: potential and limitations.

Journal: Journal of vascular and interventional radiology : JVIR 20041101

Title: [Hyperinsulinism-hyperammonemia syndrome due to a de novo mutation in exon 7 (G979A) of the glutamate dehydrogenase gene with excellent response to diazoxide].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20041101

Title: Medications used in the treatment of hypoglycemia due to congenital hyperinsulinism of infancy (HI).

Journal: Pediatric endocrinology reviews : PER 20041101

Title: [The protective effect of diazoxide on long-term heart preservation].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20041025

Title: KATP channel activation induces ischemic preconditioning of the endothelium in humans in vivo.

Journal: Circulation 20041012

Title: Rebaudioside A potently stimulates insulin secretion from isolated mouse islets: studies on the dose-, glucose-, and calcium-dependency.

Journal: Metabolism: clinical and experimental 20041001

Title: Activation of the ATP-dependent potassium channel attenuates norepinephrine-induced vasoconstriction in the human forearm.

Journal: Shock (Augusta, Ga.) 20041001

Title: Quinones and aromatic chemical compounds in particulate matter induce mitochondrial dysfunction: implications for ultrafine particle toxicity.

Journal: Environmental health perspectives 20041001

Title: Insulin secretion is stimulated by ethanol extract of Anemarrhena asphodeloides in isolated islet of healthy Wistar and diabetic Goto-Kakizaki Rats.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20041001

Title: Persistent hyperinsulinemic hypoglycemia presenting with a rare complication: West syndrome.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20041001

Title: Does the mitochondrial permeability transition have a role in preconditioning?

Journal: Circulation 20040914

Title: Diazoxide prevents mitochondrial swelling and Ca2+ accumulation in CA1 pyramidal cells after cerebral ischemia in newborn pigs.

Journal: Brain research 20040903

Title: Contribution of Akt and endothelial nitric oxide synthase to diazoxide-induced late preconditioning.

Journal: American journal of physiology. Heart and circulatory physiology 20040901

Title: Potassium-specific effects of levosimendan on heart mitochondria.

Journal: Biochemical pharmacology 20040901

Title: Zinc inhibits glutamate release via activation of pre-synaptic K channels and reduces ischaemic damage in rat hippocampus.

Journal: Journal of neurochemistry 20040901

Title: Temporary preservation of beta-cell function by diazoxide treatment in childhood type 1 diabetes.

Journal: Diabetes care 20040901

Title: Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells.

Journal: Diabetologia 20040901

Title: Endothelial protection from reperfusion injury by ischemic preconditioning and diazoxide involves a SOD-like anti-O2- mechanism.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040901

Title: Atypical Ca2+-induced Ca2+ release from a sarco-endoplasmic reticulum Ca2+-ATPase 3-dependent Ca2+ pool in mouse pancreatic beta-cells.

Journal: The Journal of physiology 20040815

Title: Diazoxide and N omega-nitro-L-arginine counteracted A beta 1-42-induced cytotoxicity.

Journal: Neuroreport 20040806

Title: Preconditioning protects by inhibiting the mitochondrial permeability transition.

Journal: American journal of physiology. Heart and circulatory physiology 20040801

Title: Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose.

Journal: American journal of physiology. Endocrinology and metabolism 20040801

Title: Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation.

Journal: Diabetes 20040801

Title: Testosterone modulates K(+)ATP channels in Sertoli cell membrane via the PLC-PIP2 pathway.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040801

Title: Functional distinctions between the mitochondrial ATP-dependent K+ channel (mitoKATP) and its inward rectifier subunit (mitoKIR).

Journal: The Journal of biological chemistry 20040730

Title: Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.

Journal: The Journal of biological chemistry 20040730

Title: Acute increases in arterial blood pressure do not reduce plasma vasopressin levels stimulated by angiotensin II or hyperosmolality in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20040701

Title: Growth hormone promotes Ca(2+)-induced Ca2+ release in insulin-secreting cells by ryanodine receptor tyrosine phosphorylation.

Journal: Molecular endocrinology (Baltimore, Md.) 20040701

Title: NO donor-activated PKC-delta plays a pivotal role in ischemic myocardial protection through accelerated opening of mitochondrial K-ATP channels.

Journal: Journal of cardiovascular pharmacology 20040701

Title: Effect of classic preconditioning and diazoxide on endothelial function and O2- and NO generation in the post-ischemic guinea-pig heart.

Journal: Cardiovascular research 20040701

Title: A case of severe diazoxide toxicity.

Journal: Paediatric anaesthesia 20040701

Title: The anti-inflammatory effect of diazoxide in coronary artery bypass grafting.

Journal: Shock (Augusta, Ga.) 20040701

Title: Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.

Journal: Diabetes 20040701

Title: Insulin feedback alters mitochondrial activity through an ATP-sensitive K+ channel-dependent pathway in mouse islets and beta-cells.

Journal: Diabetes 20040701

Title: Mutation at position -132 in the islet amyloid polypeptide ( IAPP) gene promoter enhances basal transcriptional activity through a new CRE-like binding site.

Journal: Diabetologia 20040701

Title: Preconditioning of the myocardium by volatile anesthetics.

Journal: Current medicinal chemistry. Cardiovascular and hematological agents 20040701

Title: The major glucagon-like peptide-1 metabolite, GLP-1-(9-36)-amide, does not affect glucose or insulin levels in mice.

Journal: European journal of pharmacology 20040628

Title: Potassium channel openers are uncoupling protonophores: implication in cardioprotection.

Journal: FEBS letters 20040618

Title: Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells.

Journal: The Journal of physiology 20040615

Title: Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release.

Journal: Journal of medicinal chemistry 20040603

Title: Regulation by glucose and calcium of the carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting INS-1 cells.

Journal: American journal of physiology. Endocrinology and metabolism 20040601

Title: Diazoxide preconditioning protects against neuronal cell death by attenuation of oxidative stress upon glutamate stimulation.

Journal: Journal of neuroscience research 20040601

Title: Role of calcium in pancreatic islet cell death by IFN-gamma/TNF-alpha.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040601

Title: Glucose and insulin treatment of insulinoma cells results in transcriptional regulation of a common set of genes.

Journal: Diabetes 20040601

Title: Inhibition of insulin secretion as a new drug target in the treatment of metabolic disorders.

Journal: Current medicinal chemistry 20040601

Title: Nitric oxide protects rat hepatocytes against reperfusion injury mediated by the mitochondrial permeability transition.

Journal: Hepatology (Baltimore, Md.) 20040601

Title: Diazoxide and dimethyl sulphoxide prevent cerebral hypoperfusion-related learning dysfunction and brain damage after carotid artery occlusion.

Journal: Brain research 20040522

Title: Diazoxide affects the IF1 inhibitor protein binding to F1 sector of beef heart F0F1ATPsynthase.

Journal: Biochemical pharmacology 20040515

Title: Quinine inhibits mitochondrial ATP-regulated potassium channel from bovine heart.

Journal: The Journal of membrane biology 20040515

Title: The human mitochondrial KATP channel is modulated by calcium and nitric oxide: a patch-clamp approach.

Journal: Biochimica et biophysica acta 20040512

Title: Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine.

Journal: American journal of physiology. Endocrinology and metabolism 20040501

Title: Openers of ATP-dependent K+-channels protect against a signal-transduction-linked and not freely reversible defect of insulin secretion in a rat islet transplantation model of Type 2 diabetes.

Journal: Diabetologia 20040501

Title: [The research method for investigating the role of the mitochondrial permeability transition pore in cell death].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040501

Title: Cardioprotective effects of mitochondrial KATP channels activated at different time.

Journal: Chinese medical journal 20040501

Title: Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection.

Journal: Circulation 20040413

Title: Additive antinociceptive effect of the combination of diazoxide, an activator of ATP-sensitive K+ channels, and sodium nitroprusside and dibutyryl-cGMP.

Journal: European journal of pharmacology 20040405

Title: Exogenous nitric oxide generates ROS and induces cardioprotection: involvement of PKG, mitochondrial KATP channels, and ERK.

Journal: American journal of physiology. Heart and circulatory physiology 20040401

Title: A store-operated mechanism determines the activity of the electrically excitable glucagon-secreting pancreatic alpha-cell.

Journal: Cell calcium 20040401

Title: Attenuation of hyperinsulinemia by NN414, a SUR1/Kir6.2 selective K-adenosine triphosphate channel opener, improves glucose tolerance and lipid profile in obese Zucker rats.

Journal: Metabolism: clinical and experimental 20040401

Title: [Diagnosis and treatment of insulinoma].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20040401

Title: Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor.

Journal: The Journal of biological chemistry 20040319

Title: Chromatographic multivariate quality control of pharmaceuticals giving strongly overlapped peaks based on the chromatogram profile.

Journal: Journal of chromatography. A 20040312

Title: Influence of central administration ATP-dependent K+ channel on morphine state-dependent memory of passive avoidance.

Journal: European journal of pharmacology 20040308

Title: Evidence for mitochondrial K+ channels and their role in cardioprotection.

Journal: Circulation research 20040305

Title: ROS are required for rapid reactivation of Na+/Ca2+ exchanger in hypoxic reoxygenated guinea pig ventricular myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20040301

Title: Diazoxide enhances adipose tissue protein kinase B activation and glucose transporter-4 expression in obese Zucker rats.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20040301

Title: ROS-mediated ERK activation in delayed protection from anoxic preconditioning in neonatal rat cardiomyocytes.

Journal: Chinese medical journal 20040301

Title: Mechanism of apoptosis induced by diazoxide, a K+ channel opener, in HepG2 human hepatoma cells.

Journal: Archives of pharmacal research 20040301

Title: Influence of potassium channel modulators on morphine state-dependent memory of passive avoidance.

Journal: Behavioural pharmacology 20040301

Title: Adenosine and a nitric oxide donor enhances cardioprotection by preconditioning with isoflurane through mitochondrial adenosine triphosphate-sensitive K+ channel-dependent and -independent mechanisms.

Journal: Anesthesiology 20040301

Title: Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo.

Journal: Anesthesiology 20040301

Title: Influence of fasting on the effects of diazoxide in the ischemic-reperfused rat heart.

Journal: Journal of physiology and biochemistry 20040301

Title: Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic beta-cells.

Journal: European journal of pharmacology 20040220

Title: Diazoxide causes early activation of cardiac sarcolemmal KATP channels during metabolic inhibition by an indirect mechanism.

Journal: Cardiovascular research 20040215

Title: Delayed preconditioning of the human myocardium: signal transduction and clinical implications.

Journal: Cardiovascular research 20040215

Title: Electro-acupuncture preconditioning abrogates the elevation of c-Fos and c-Jun expression in neonatal hypoxic-ischemic rat brains induced by glibenclamide, an ATP-sensitive potassium channel blocker.

Journal: Brain research 20040213

Title: 3-trifluoromethyl-4-nitro-5-arylpyrazoles are novel K(ATP) channel agonists.

Journal: Bioorganic & medicinal chemistry letters 20040209

Title: The mitochondrial K(ATP) channel opener BMS-191095 induces neuronal preconditioning.

Journal: Neuroreport 20040209

Title: Syntaxin-1A binds the nucleotide-binding folds of sulphonylurea receptor 1 to regulate the KATP channel.

Journal: The Journal of biological chemistry 20040206

Title: Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells.

Journal: Endocrinology 20040201

Title: Autosomal-dominant hypertension with type E brachydactyly is caused by rearrangement on the short arm of chromosome 12.

Journal: Hypertension (Dallas, Tex. : 1979) 20040201

Title: Molecular mechanisms of the inhibitory effects of propofol and thiamylal on sarcolemmal adenosine triphosphate-sensitive potassium channels.

Journal: Anesthesiology 20040201

Title: Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes.

Journal: Diabetologia 20040201

Title: Difference in the cardioprotective mechanisms between ischemic preconditioning and pharmacological preconditioning by diazoxide in rat hearts.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20040201

Title: Roles of mitochondria in health and disease.

Journal: Diabetes 20040201

Title: Visualization of the specific interaction of sulfonylurea-incorporated polymer with insulinoma cell line MIN6.

Journal: Journal of biochemistry 20040201

Title: Severe transient neonatal hyperinsulinism associated with hyperlactataemia in non-asphyxiated infants.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20040201

Title: [Congenital hyperinsulinism in 15 infants, 1981-1999; experiences and new insights].

Journal: Nederlands tijdschrift voor geneeskunde 20040117

Title: Modulation of the excitability of cholinergic basal forebrain neurones by KATP channels.

Journal: The Journal of physiology 20040115

Title: Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection.

Journal: American journal of physiology. Heart and circulatory physiology 20040101

Title: Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing.

Journal: The Biochemical journal 20040101

Title: Regulation by sulfanylurea receptor type 1 of a non-selective cation channel involved in cytotoxic edema of reactive astrocytes.

Journal: Journal of neurosurgical anesthesiology 20040101

Title: Binding of sulfonylurea by AtMRP5, an Arabidopsis multidrug resistance-related protein that functions in salt tolerance.

Journal: Plant physiology 20040101

Title: Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart.

Journal: Acta pharmacologica Sinica 20040101

Title: Nine weeks of bedtime diazoxide is well tolerated and improves beta-cell function in subjects with Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20040101

Title: Hyperinsulinaemic hypoglycaemia in preterm neonates.

Journal: Archives of disease in childhood. Fetal and neonatal edition 20040101

Title: Diazoxide provides protection to human myocardium in vitro that is concentration dependent.

Journal: The Annals of thoracic surgery 20040101

Title: Subcellular heterogeneity in mitochondrial red-ox responses to KATP channel agonists in freshly isolated rabbit cardiomyocytes.

Journal: Molecular and cellular biochemistry 20040101

Title: Nesidioblastosis treated successfully by 85% pancreatectomy.

Journal: The Kurume medical journal 20040101

Title: [Study of the mechanism of action of novel fluoro-containing analogs of diazoxide on the vascular tonus].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101

Title: [Fluorine-containing analog of diazoxide prevented apoptosis in neonatal cardiomyocytes during anoxia-reoxygenation].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101

Title: The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K+ channels in the rat insulinoma cell line, CRI-G1.

Journal: BMC pharmacology 20040101

Title: [The effect of K(ATP)-channel activation on the electrical stability of myocardium in rats with postinfarction cardiosclerosis].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20040101

Title: [Persistent hyperinsulinemic hypoglycemia. Two case reports].

Journal: Cirugia y cirujanos 20040101

Title: Hirsutism: common clinical problem or index of serious disease?

Journal: MedGenMed : Medscape general medicine 20040101

Title: Mechanisms of cardioprotective effects of magnesium on hypoxia-reoxygenation-induced injury.

Journal: Experimental and clinical cardiology 20040101

Title: Palmitate-induced Ca2+-signaling in pancreatic beta-cells.

Journal: Molecular and cellular endocrinology 20031230

Title: Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

Journal: Biochemical and biophysical research communications 20031226

Title: Investigation of the subunit composition and the pharmacology of the mitochondrial ATP-dependent K+ channel in the brain.

Journal: Brain research 20031219

Title: Mitochondrial ATP-sensitive potassium channels in surgical cardioprotection.

Journal: Archives of biochemistry and biophysics 20031215

Title: Effects of the beta-carbolines, harmane and pinoline, on insulin secretion from isolated human islets of Langerhans.

Journal: European journal of pharmacology 20031215

Title: ATP-sensitive K+ channels in renal mitochondria.

Journal: American journal of physiology. Renal physiology 20031201

Title: Amiodarone inhibits sarcolemmal but not mitochondrial KATP channels in Guinea pig ventricular cells.

Journal: The Journal of pharmacology and experimental therapeutics 20031201

Title: The cardioprotective effects of Na+/H+ exchange inhibition and mitochondrial KATP channel activation are additive in the isolated rat heart.

Journal: Pflugers Archiv : European journal of physiology 20031201

Title: Novel pharmacological preconditioning with diazoxide attenuates myocardial stunning in coronary artery bypass grafting.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20031201

Title: Time course of vascular reactivity to contracting and relaxing agents after endothelial denudation by balloon angioplasty in rat carotid artery.

Journal: Atherosclerosis 20031201

Title: Trimethoprim-sulfamethoxazole induced prolonged hypoglycemia in an infant with MHC class II deficiency: diazoxide as a treatment option.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20031201

Title: Comparative effects of efaroxan and beta-carbolines on the secretory activity of rodent and human beta cells.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Early biochemical and histological alterations in rat corticoencephalic cell cultures following metabolic damage and treatment with modulators of mitochondrial ATP-sensitive potassium channels.

Journal: Neurochemistry international 20031101

Title: Interactions of diazoxide with frusemide, spironolactone, and acetylsalicylic acid in a patient with hyperinsulinism of Infancy and Fallot tetralogy.

Journal: European journal of pediatrics 20031101

Title: Enhanced cardioprotection of the rat heart during hypothermic storage with combined Na+ - H+ exchange inhibition and ATP-dependent potassium channel activation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031101

Title: Heart mitochondria contain functional ATP-dependent K+ channels.

Journal: Journal of molecular and cellular cardiology 20031101

Title: Ca2+ influx does not trigger glucose-induced traffic of the insulin granules and alteration of their distribution.

Journal: Experimental biology and medicine (Maywood, N.J.) 20031101

Title: Diazoxide induces delayed pre-conditioning in cultured rat cortical neurons.

Journal: Journal of neurochemistry 20031101

Title: ATP-dependent K+ channels in renal ischemia reperfusion injury.

Journal: Renal failure 20031101

Title: 1,5-Anhydroglucitol stimulates insulin release in insulinoma cell lines.

Journal: Biochimica et biophysica acta 20031013

Title: Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues.

Journal: Diabetologia 20031001

Title: Intracellular mechanism of mitochondrial adenosine triphosphate-sensitive potassium channel activation with isoflurane.

Journal: Anesthesia and analgesia 20031001

Title: Isoflurane pretreatment has immediate and delayed protective effects against cytokine-induced injury in endothelial and vascular smooth muscle cells.

Journal: Anesthesiology 20031001

Title: Intra-myocyte ion homeostasis during ischemia-reperfusion injury: effects of pharmacologic preconditioning and controlled reperfusion.

Journal: The Annals of thoracic surgery 20031001

Title: Early ischemic preconditioning for spinal cord protection.

Journal: The Annals of thoracic surgery 20031001

Title: A case of partial trisomy 13 presenting with hyperinsulinaemic hypoglycaemia.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20031001

Title: HL-1 myocytes exhibit PKC and K(ATP) channel-dependent delta opioid preconditioning.

Journal: The Journal of surgical research 20031001

Title: Effectiveness of octreotide in a case of refractory sulfonylurea-induced hypoglycemia.

Journal: The Journal of emergency medicine 20031001

Title: ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart.

Journal: Current vascular pharmacology 20031001

Title: Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030917

Title: Both metabolic inhibition and mitochondrial K(ATP) channel opening are myoprotective and initiate a compensatory sarcolemmal outward membrane current.

Journal: Circulation 20030909

Title: Combined pharmacological preconditioning with a G-protein-coupled receptor agonist, a mitochondrial KATP channel opener and a nitric oxide donor mimics ischaemic preconditioning.

Journal: Clinical and experimental pharmacology & physiology 20030901

Title: Chemical preconditioning prevents paradoxical increase in glutamate release during ischemia by activating ATP-dependent potassium channels in gerbil hippocampus.

Journal: Experimental neurology 20030901

Title: ATP-sensitive potassium channels induced in liver cells after transfection with insulin cDNA and the GLUT 2 transporter regulate glucose-stimulated insulin secretion.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901

Title: The K+ channel openers diazoxide and NS1619 induce depolarization of mitochondria and have differential effects on cell Ca2+ in CD34+ cell line KG-1a.

Journal: Experimental hematology 20030901

Title: P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.

Journal: Journal of molecular and cellular cardiology 20030901

Title: Evidence for rapid 'metabolic switching' through lipoprotein lipase occupation of endothelial-binding sites.

Journal: Journal of molecular and cellular cardiology 20030901

Title: Circulating triglyceride lipolysis facilitates lipoprotein lipase translocation from cardiomyocyte to myocardial endothelial lining.

Journal: Cardiovascular research 20030901

Title: [Sevoflurane anesthesia for pancreatectomy in an infant with nesidioblastosis].

Journal: Masui. The Japanese journal of anesthesiology 20030901

Title: Protective effects of the potassium channel opener-diazoxide against injury in neonatal rat ventricular myocytes.

Journal: General physiology and biophysics 20030901

Title: Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.

Journal: Circulation 20030812

Title: Activation of the KATP channel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH.

Journal: American journal of physiology. Endocrinology and metabolism 20030801

Title: Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets.

Journal: Endocrinology 20030801

Title: N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits.

Journal: The EMBO journal 20030801

Title: K(ATP) channels and pancreatic islet blood flow in anesthetized rats: increased blood flow induced by potassium channel openers.

Journal: Diabetes 20030801

Title: Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death.

Journal: Journal of neurochemistry 20030801

Title: Insulin-like growth factor-1 prevents loss of electrochemical gradient in cardiac muscle mitochondria via activation of PI 3 kinase/Akt pathway.

Journal: Molecular and cellular endocrinology 20030731

Title: Degradation of phosphatidylethanol counteracts the apparent phospholipase D-mediated formation in heart and other organs.

Journal: Biochimica et biophysica acta 20030721

Title: Toward tissue-selective pancreatic B-cells KATP channel openers belonging to 3-alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides.

Journal: Journal of medicinal chemistry 20030717

Title: Diazoxide pretreatment induces delayed preconditioning in astrocytes against oxygen glucose deprivation and hydrogen peroxide-induced toxicity.

Journal: Journal of neuroscience research 20030715

Title: Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress.

Journal: Stroke 20030701

Title: Effects of fatty acids in isolated mitochondria: implications for ischemic injury and cardioprotection.

Journal: American journal of physiology. Heart and circulatory physiology 20030701

Title: [125I]A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding.

Journal: Molecular pharmacology 20030701

Title: Long-term follow-up of 114 patients with congenital hyperinsulinism.

Journal: European journal of endocrinology 20030701

Title: Mitochondrial plasticity in classical ischemic preconditioning-moving beyond the mitochondrial KATP channel.

Journal: Cardiovascular research 20030701

Title: Ischaemic preconditioning and a mitochondrial KATP channel opener both produce cardioprotection accompanied by F1F0-ATPase inhibition in early ischaemia.

Journal: Basic research in cardiology 20030701

Title: Effect of high concentration of glucose on dopamine release from pheochromocytoma-12 cells.

Journal: Metabolism: clinical and experimental 20030701

Title: Integrated pharmacological preconditioning in combination with adenosine, a mitochondrial KATP channel opener and a nitric oxide donor.

Journal: The Journal of thoracic and cardiovascular surgery 20030701

Title: Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression.

Journal: The Journal of physiology 20030615

Title: ATP-sensitive potassium channels in rat primary afferent neurons: the effect of neuropathic injury and gabapentin.

Journal: Neuroscience letters 20030612

Title: Elevated dietary salt suppresses renin secretion but not thirst evoked by arterial hypotension in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030601

Title: Diazoxide triggers cardioprotection against apoptosis induced by oxidative stress.

Journal: American journal of physiology. Heart and circulatory physiology 20030601

Title: Antiangiogenic effect of KR-31372 by apoptosis via mediation of mitochondrial KATP channel opening and the phosphatase and tensin homolog deleted from chromosome 10 phosphorylation.

Journal: The Journal of pharmacology and experimental therapeutics 20030601

Title: Insulin inhibits rat hippocampal neurones via activation of ATP-sensitive K+ and large conductance Ca2+-activated K+ channels.

Journal: Neuropharmacology 20030601

Title: Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass in vivo in adult rats.

Journal: Endocrinology 20030601

Title: Mitochondrial ATP-sensitive potassium channel: a novel site for neuroprotection.

Journal: Investigative ophthalmology & visual science 20030601

Title: Acetylcholine-induced production of reactive oxygen species in adult rabbit ventricular myocytes is dependent on phosphatidylinositol 3- and Src-kinase activation and mitochondrial K(ATP) channel opening.

Journal: Journal of molecular and cellular cardiology 20030601

Title: Functional involvement of sulphonylurea receptor (SUR) type 1 and 2B in the activity of pig urethral ATP-sensitive K+ channels.

Journal: British journal of pharmacology 20030601

Title: Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.

Journal: Cardiovascular research 20030601

Title: Coronary endothelial dysfunction after ischemia and reperfusion and its prevention by ischemic preconditioning.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20030601

Title: Differential activation of protein kinase C between ischemic and pharmacological preconditioning in the rabbit heart.

Journal: The Japanese journal of physiology 20030601

Title: Surgery of persistent hyperinsulinaemic hypoglycaemia.

Journal: Seminars in neonatology : SN 20030601

Title: Mechanisms of delayed electrical uncoupling induced by ischemic preconditioning.

Journal: Circulation research 20030530

Title: Activation of peripheral ATP-sensitive K+ channels mediates the antinociceptive effect of Crotalus durissus terrificus snake venom.

Journal: European journal of pharmacology 20030523

Title: Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells.

Journal: The Journal of biological chemistry 20030516

Title: Isoflurane activates rat mitochondrial ATP-sensitive K+ channels reconstituted in lipid bilayers.

Journal: American journal of physiology. Heart and circulatory physiology 20030501

Title: Contrasting roles of a novel K+ channel blocker and a K+ channel opener on electro-mechanical activity in canine heart tissue.

Journal: International journal of cardiology 20030501

Title: Binding and effect of K ATP channel openers in the absence of Mg2+.

Journal: British journal of pharmacology 20030501

Title: Cellular uptake of a catechol iron chelator and chloroquine into Plasmodium falciparum infected erythrocytes.

Journal: Biochemical pharmacology 20030415

Title: Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.

Journal: European journal of pharmacology 20030411

Title: Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels.

Journal: Endocrinology 20030401

Title: Persistent hyperinsulinemic hypoglycaemia followed as benign infantile convulsion.

Journal: Seizure 20030401

Title: Insulin does not mediate glucose stimulation of proinsulin biosynthesis.

Journal: Diabetes 20030401

Title: Targeting nucleotide-requiring enzymes: implications for diazoxide-induced cardioprotection.

Journal: American journal of physiology. Heart and circulatory physiology 20030401

Title: Activation of Akt is essential for acetylcholine to trigger generation of oxygen free radicals.

Journal: Cardiovascular research 20030401

Title: Modulation of mitochondrial adenosine triphosphate-sensitive potassium channels and sodium-hydrogen exchange provide additive protection from severe ischemia-reperfusion injury.

Journal: The Journal of thoracic and cardiovascular surgery 20030401

Title: Adenine nucleotide translocase mediates the K(ATP)-channel-openers-induced proton and potassium flux to the mitochondrial matrix.

Journal: Journal of bioenergetics and biomembranes 20030401

Title: [Changes in cardiac resistance to arrhythmogenic effects during ATP-dependent K+ channel activation].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20030401

Title: Synthesis and biological activity of 3,3-diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells.

Journal: Bioorganic & medicinal chemistry 20030320

Title: Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria.

Journal: The Journal of physiology 20030315

Title: MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning.

Journal: Circulation 20030304

Title: Mechanism of inhibitory actions of oxidizing agents on calcium-activated potassium current in cultured pigment epithelial cells of the human retina.

Journal: Investigative ophthalmology & visual science 20030301

Title: Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death.

Journal: Journal of neurochemistry 20030301

Title: Pharmacological agents that directly modulate insulin secretion.

Journal: Pharmacological reviews 20030301

Title: The effects of KATP channel modulators on counterregulatory responses and cognitive function during acute controlled hypoglycaemia in healthy men: a pilot study.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20030301

Title: Modulation of the trafficking efficiency and functional properties of ATP-sensitive potassium channels through a single amino acid in the sulfonylurea receptor.

Journal: The Journal of biological chemistry 20030227

Title: Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.

Journal: Circulation 20030211

Title: Differential actions of cardioprotective agents on the mitochondrial death pathway.

Journal: Circulation research 20030207

Title: Receptor and non-receptor-dependent mechanisms of cardioprotection with adenosine.

Journal: American journal of physiology. Heart and circulatory physiology 20030201

Title: Inhibition of vascular ATP-sensitive K+ channels does not affect reactive hyperemia in human forearm.

Journal: American journal of physiology. Heart and circulatory physiology 20030201

Title: Differential sensitivity of atrial and ventricular K(ATP) channels to metabolic inhibition.

Journal: Cardiovascular research 20030201

Title: Differential effects of sulphonylureas on the vasodilatory response evoked by K(ATP) channel openers.

Journal: Fundamental & clinical pharmacology 20030201

Title: The mitochondrial K(ATP) channel and cardioprotection.

Journal: The Annals of thoracic surgery 20030201

Title: Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population.

Journal: Diabetologia 20030201

Title: Prolonged hyperinsulinemic hypoglycemia in a small for date preterm.

Journal: Minerva pediatrica 20030201

Title: Leptin fully suppresses acetylcholine-induced insulin secretion and is reversed by tolbutamide in isolated perfused chicken pancreas.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030201

Title: Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells.

Journal: The Biochemical journal 20030115

Title: Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels.

Journal: Stroke 20030101

Title: Increased vulnerability to ischemia/reperfusion-induced ventricular tachyarrhythmias by pre-ischemic inhibition of nitric oxide synthase in isolated rat hearts.

Journal: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20030101

Title: Involvement of mitogen-activated protein kinases and reactive oxygen species in the inotropic action of ouabain on cardiac myocytes. A potential role for mitochondrial K(ATP) channels.

Journal: Molecular and cellular biochemistry 20030101

Title: Effects of sulfonylureas on K(ATP) channel-dependent vasodilation.

Journal: Journal of diabetes and its complications 20030101

Title: Protection of rat pancreatic islets by potassium channel openers against alloxan, sodium nitroprusside and interleukin-1beta mediated suppression--possible involvement of the mitochondrial membrane potential.

Journal: Diabetologia 20030101

Title: [Malignant insulinoma in an 84-year-old woman].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20030101

Title: [Treatment of insulinoma with diazoxide].

Journal: Medicina 20030101

Title: Ischemic and pharmacological induction of delayed cellular protection in iNOS gene-disrupted mice myocytes.

Journal: Polish journal of pharmacology 20030101

Title: Role of mitochondrial KATP channels and protein kinase C in ischaemic preconditioning.

Journal: Clinical and experimental pharmacology & physiology 20030101

Title: Gender differences in effects of pinacidil but not diazoxide on heart automatism in the isolated guinea pig right atria.

Journal: Polish journal of pharmacology 20030101

Title: Persistent hyperinsulinemic neonatal hypoglycemia caused by focal nesidioblastosis. Preoperative diagnosis by pancreatic venous sampling.

Journal: Hormones (Athens, Greece) 20030101

Title: Methyl pyruvate stimulates pancreatic beta-cells by a direct effect on KATP channels, and not as a mitochondrial substrate.

Journal: The Biochemical journal 20021215

Title: The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration.

Journal: The Journal of physiology 20021215

Title: Opening of potassium channels modulates mitochondrial function in rat skeletal muscle.

Journal: Biochimica et biophysica acta 20021202

Title: Expression and activity of potassium ion channels in human prostate cancer.

Journal: Cancer letters 20021201

Title: Mitochondrial Ca2+ uptake is important over low [Ca2+]i range in arterial smooth muscle.

Journal: American journal of physiology. Heart and circulatory physiology 20021201

Title: The role of mitochondrial K(ATP) channels in the antiarrhythmic effects of ischaemic preconditioning in dogs.

Journal: British journal of pharmacology 20021201

Title: The role of mitochondrial K(ATP) channels in antiarrhythmic effects of ischaemic preconditioning in dogs.

Journal: British journal of pharmacology 20021201

Title: Serum inhibin B in polycystic ovary syndrome: regulation by insulin and luteinizing hormone.

Journal: The Journal of clinical endocrinology and metabolism 20021201

Title: Diazoxide in the treatment of schizophrenia: novel application of potassium channel openers in the treatment of schizophrenia.

Journal: Journal of clinical pharmacy and therapeutics 20021201

Title: Rapid insulin assay for intraoperative confirmation of complete resection of insulinomas.

Journal: Surgery 20021201

Title: Improved beta cell function after short-term treatment with diazoxide in obese subjects with type 2 diabetes.

Journal: Diabetes & metabolism 20021201

Title: Uncontrolled insulin secretion from a childhood pancreatic beta-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels.

Journal: Endocrine-related cancer 20021201

Title: Diazoxide amelioration of myocardial injury and mitochondrial damage during cardiac surgery.

Journal: The Annals of thoracic surgery 20021201

Title: Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.

Journal: The Journal of biological chemistry 20021122

Title: The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking.

Journal: European journal of biochemistry 20021101

Title: Nicorandil and leukocyte activation.

Journal: Journal of cardiovascular pharmacology 20021101

Title: BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.

Journal: The Journal of clinical endocrinology and metabolism 20021101

Title: 2-alkyl-3-Alkylamino-2H-Benzo- and pyridothiadiazine 1,1-dioxides: from K+ATP channel openers to Ca++ channel blockers?

Journal: Biological chemistry 20021101

Title: Time and amplitude regulation of pulsatile insulin secretion by triggering and amplifying pathways in mouse islets.

Journal: FEBS letters 20021023

Title: Synthesis and evaluation of 7-substituted-3-cyclobutylamino-4H-1,2,4-benzothiadiazine-1,1-dioxide derivatives as K(ATP) channel agonists.

Journal: Bioorganic & medicinal chemistry letters 20021021

Title: Rescue of beta-cell exhaustion by diazoxide after the development of diabetes mellitus in rats with streptozotocin-induced diabetes.

Journal: European journal of pharmacology 20021018

Title: Dynamics of glucose-induced membrane recruitment of protein kinase C beta II in living pancreatic islet beta-cells.

Journal: The Journal of biological chemistry 20021004

Title: Cardioprotection by multiple preconditioning cycles does not require mitochondrial K(ATP) channels in pigs.

Journal: American journal of physiology. Heart and circulatory physiology 20021001

Title: Long-term administration of nicorandil abolishes ischemic and pharmacologic preconditioning of the human myocardium: role of mitochondrial adenosine triphosphate-dependent potassium channels.

Journal: The Journal of thoracic and cardiovascular surgery 20021001

Title: Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life.

Journal: Diabetes 20021001

Title: Cell-type specific depression of neuronal excitability in rat hippocampus by activation of ATP-sensitive potassium channels.

Journal: European biophysics journal : EBJ 20021001

Title: Study of a glucose-activated anion-selective channel in rat pancreatic beta-cells.

Journal: Pflugers Archiv : European journal of physiology 20021001

Title: [PHHI (persistent hyperinsulinemic hypoglycemia of infancy)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20021001

Title: Rapid effect of testosterone on rat Sertoli cell membrane potential. Relationship with K+ATP channels.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20021001

Title: Persistent hyperinsulinaemic hypoglycaemia of infancy: case report.

Journal: East African medical journal 20021001

Title: 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells.

Journal: Journal of medicinal chemistry 20020912

Title: The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related.

Journal: The Journal of biological chemistry 20020906

Title: MitoK(ATP) opener, diazoxide, reduces neuronal damage after middle cerebral artery occlusion in the rat.

Journal: American journal of physiology. Heart and circulatory physiology 20020901

Title: Glucose-sensing in glucagon-like peptide-1-secreting cells.

Journal: Diabetes 20020901

Title: Opening of ATP-sensitive potassium channels causes generation of free radicals in vascular smooth muscle cells.

Journal: Basic research in cardiology 20020901

Title: Delta opioid agonists and volatile anesthetics facilitate cardioprotection via potentiation of K(ATP) channel opening.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020901

Title: Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia.

Journal: The Annals of thoracic surgery 20020901

Title: Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?

Journal: Cardiovascular research 20020815

Title: Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.

Journal: Cardiovascular research 20020815

Title: Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene.

Journal: Cardiovascular research 20020815

Title: Effects of mitochondrial K(ATP) modulators on cardioprotection induced by chronic high altitude hypoxia in rats.

Journal: Cardiovascular research 20020815

Title: Ischemic preconditioning protection against stunning in conscious diabetic sheep: role of glucose, insulin, sarcolemmal and mitochondrial KATP channels.

Journal: Cardiovascular research 20020815

Title: The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart.

Journal: Cardiovascular research 20020815

Title: Glucose lowering effect of aqueous extract of Enicostemma littorale Blume in diabetes: a possible mechanism of action.

Journal: Journal of ethnopharmacology 20020801

Title: Neonatal hyperinsulinemic hypoglycemia. Two case reports.

Journal: Minerva pediatrica 20020801

Title: Evidence that the novel imidazoline compound FT005 is an alpha(2)-adrenoceptor agonist.

Journal: British journal of pharmacology 20020801

Title: Sulfatide controls insulin secretion by modulation of ATP-sensitive K(+)-channel activity and Ca(2+)-dependent exocytosis in rat pancreatic beta-cells.

Journal: Diabetes 20020801

Title: K(ATP) channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart.

Journal: The Journal of physiology 20020801

Title: Diazoxide for cerebral protection during deep hypothermic circulatory arrest: is it really safe?

Journal: The Annals of thoracic surgery 20020801

Title: Pancreatectomy extension in persistent hyperinsulinaemic hypoglycaemia: a new strategy.

Journal: European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20020801

Title: Opening of mitochondrial K+ channels increases ischemic ATP levels by preventing hydrolysis.

Journal: Journal of bioenergetics and biomembranes 20020801

Title: Persistent hyperinsulinemic hypoglycemia of infancy: experience at Siriraj Hospital.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020801

Title: Glucagon is paradoxically secreted at high concentrations of glucose in rat pancreas perfused with diazoxide.

Journal: Diabetes, nutrition & metabolism 20020801

Title: The role of myocardial KATP-channel blockade in the protective effects of glibenclamide against ischaemia in the rat heart.

Journal: Pharmacology & toxicology 20020801

Title: Activation of mitochondrial ATP-sensitive potassium channels prevents neuronal cell death after ischemia in neonatal rats.

Journal: Neuroscience letters 20020726

Title: Mitochondrial K(ATP) channel openers activate the ERK kinase by an oxidant-dependent mechanism.

Journal: American journal of physiology. Cell physiology 20020701

Title: Role of nitric oxide synthase isoforms in glucose-stimulated insulin release.

Journal: American journal of physiology. Cell physiology 20020701

Title: Ketamine abolishes ischemic preconditioning through inhibition of K(ATP) channels in rabbit hearts.

Journal: American journal of physiology. Heart and circulatory physiology 20020701

Title: Mechanisms by which opening the mitochondrial ATP- sensitive K(+) channel protects the ischemic heart.

Journal: American journal of physiology. Heart and circulatory physiology 20020701

Title: Opening of mitochondrial K(ATP) channel occurs downstream of PKC-epsilon activation in the mechanism of preconditioning.

Journal: American journal of physiology. Heart and circulatory physiology 20020701

Title: Effect of metabolic inhibition on glimepiride block of native and cloned cardiac sarcolemmal K(ATP) channels.

Journal: British journal of pharmacology 20020701

Title: Suppression of human tumor cell proliferation through mitochondrial targeting.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020701

Title: Volatile anesthetics mimic cardiac preconditioning by priming the activation of mitochondrial K(ATP) channels via multiple signaling pathways.

Journal: Anesthesiology 20020701

Title: Differential effects of anesthetics on mitochondrial K(ATP) channel activity and cardiomyocyte protection.

Journal: Anesthesiology 20020701

Title: Effect of pretreatment with adenosine, diazoxide or ischemic preconditioning on ischemia- reperfusion injury in the limbs of rats.

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020701

Title: Oral hypoglycemic sulfonylurea glimepiride preserves the myoprotective effects of ischemic preconditioning.

Journal: The Journal of surgical research 20020615

Title: Diazoxide opens the mitochondrial permeability transition pore and alters Ca2+ transients in rat ventricular myocytes.

Journal: Circulation 20020604

Title: The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener.

Journal: Diabetes 20020601

Title: Chronic suppression of insulin by diazoxide alters the activities of key enzymes regulating hepatic gluconeogenesis in Zucker rats.

Journal: European journal of endocrinology 20020601

Title: Clinically relevant concentrations of propofol have no effect on adenosine triphosphate-sensitive potassium channels in rat ventricular myocytes.

Journal: Anesthesiology 20020601

Title: Modulation of a plant mitochondrial K+ATP channel and its involvement in cytochrome c release.

Journal: Journal of bioenergetics and biomembranes 20020601

Title: Identification of a familial hyperinsulinism-causing mutation in the sulfonylurea receptor 1 that prevents normal trafficking and function of KATP channels.

Journal: The Journal of biological chemistry 20020510

Title: Troglitazone ameliorates lipotoxicity in the beta cell line INS-1 expressing PPAR gamma.

Journal: Diabetes research and clinical practice 20020501

Title: High-performance liquid chromatographic method with ultraviolet detection for the determination of dapsone and its hydroxylated metabolite in human plasma.

Journal: Biomedical chromatography : BMC 20020501

Title: Contribution of the endoplasmic reticulum to the glucose-induced [Ca(2+)](c) response in mouse pancreatic islets.

Journal: American journal of physiology. Endocrinology and metabolism 20020501

Title: Mitochondrial ATP-sensitive K+ channels influence force development and anoxic contractility in a flatfish, yellowtail flounder Limanda ferruginea, but not Atlantic cod Gadus morhua heart.

Journal: The Journal of experimental biology 20020501

Title: Effects of K(ATP) channel modulators on acetylcholine release from guinea-pig isolated atria and small intestine.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020501

Title: Cardiomyocyte resistance to doxorubicin mediated by A(3) adenosine receptor.

Journal: Journal of molecular and cellular cardiology 20020501

Title: [Hirsutism and hypertrichosis in adults: investigations and treatment].

Journal: Annales de dermatologie et de venereologie 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels.

Journal: Neurochemistry international 20020401

Title: Correlation between GABA release from rat islet beta-cells and their metabolic state.

Journal: American journal of physiology. Endocrinology and metabolism 20020401

Title: Preconditioning blocks cardiocyte apoptosis: role of K(ATP) channels and PKC-epsilon.

Journal: American journal of physiology. Heart and circulatory physiology 20020401

Title: Glucosamine-induced beta-cell dysfunction: a possible involvement of glucokinase or glucose-transporter type 2.

Journal: Pancreas 20020401

Title: The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy.

Journal: Diabetes 20020401

Title: Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020401

Title: Effect of ischemic preconditioning and mitochondrial KATP channel openers on chronic left ventricular remodeling in the ischemic-reperfused rat heart.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20020401

Title: Radio-frequency ablation for symptom control in a patient with metastatic pancreatic insulinoma.

Journal: Clinical endocrinology 20020401

Title: Functional roles of KATP channels in vascular smooth muscle.

Journal: Clinical and experimental pharmacology & physiology 20020401

Title: Effects of K(ATP) channel openers, P-1075, pinacidil, and diazoxide, on energetics and contractile function in isolated rat hearts.

Journal: Journal of molecular and cellular cardiology 20020401

Title: Compound heterozygosity for the common sulfonylurea receptor mutations can cause mild diazoxide-sensitive hyperinsulinism.

Journal: Clinical pediatrics 20020401

Title: The reactivity of serotonin, acetylcholine and kcl-induced contractions to relaxant agents in the rat gastric fundus.

Journal: Pharmacological research 20020401

Title: Diazoxide protects the rabbit heart following cardioplegic ischemia.

Journal: Molecular and cellular biochemistry 20020401

Title: ATP-dependent potassium channel mediates neuroprotection by chemical preconditioning with 3-nitropropionic acid in gerbil hippocampus.

Journal: Neuroscience letters 20020301

Title: Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes.

Journal: Clinical science (London, England : 1979) 20020301

Title: Determination of the specific interaction between sulfonylurea-incorporated polymer and rat islets.

Journal: Journal of biochemistry 20020301

Title: Selective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20020301

Title: AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.

Journal: European journal of pharmacology 20020301

Title: Membrane potential dependent modulations of calcium oscillations in insulin-secreting INS-1 cells.

Journal: Cell calcium 20020301

Title: Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation.

Journal: American journal of physiology. Heart and circulatory physiology 20020201

Title: Overexpression of the Na/Ca exchanger shapes stimulus-induced cytosolic Ca(2+) oscillations in insulin-producing BRIN-BD11 cells.

Journal: Diabetes 20020201

Title: Triggering of insulin release by a combination of cAMP signal and nutrients: an ATP-sensitive K+ channel-independent phenomenon.

Journal: Diabetes 20020201

Title: The effects of cerulenin, an inhibitor of protein acylation, on the two phases of glucose-stimulated insulin secretion.

Journal: Diabetes 20020201

Title: Diazoxide and pinacidil uncouple pyruvate-malate-induced mitochondrial respiration.

Journal: Journal of bioenergetics and biomembranes 20020201

Title: Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20020201

Title: Persistent hyperinsulinaemic hypoglycaemia.

Journal: Seminars in neonatology : SN 20020201

Title: ATP-sensitive K(+) channels composed of Kir6.1 and SUR2B subunits in guinea pig gastric myocytes.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020101

Title: Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals.

Journal: Diabetes 20020101

Title: ATP-independent anoxic activation of ATP-sensitive K+ channels in dorsal vagal neurons of juvenile mice in situ.

Journal: Neuroscience 20020101

Title: Heterogeneity of persistent hyperinsulinaemic hypoglycaemia. A series of 175 cases.

Journal: European journal of pediatrics 20020101

Title: Anaesthetic management of a case of nesidioblastosis for subtotal pancreatectomy.

Journal: Paediatric anaesthesia 20020101

Title: Pharmacological and ischemic preconditioning of the human myocardium: mitoK(ATP) channels are upstream and p38MAPK is downstream of PKC.

Journal: BMC physiology 20020101

Title: Voltage-gated potassium ion channels in colon cancer.

Journal: Oncology reports 20020101

Title: ABCC8 (SUR1) and KCNJ11 (KIR6.2) mutations in persistent hyperinsulinemic hypoglycemia of infancy and evaluation of different therapeutic measures.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20020101

Title: Study of the insulinotropic effect of the novel antihyperglycemic agent KAD-1229 using HIT T15 cells, a hamster's insulinoma cell line.

Journal: Arzneimittel-Forschung 20020101

Title: Drugs for treatment of very high blood pressure during pregnancy.

Journal: The Cochrane database of systematic reviews 20020101

Title: On the effect of diazoxide on isolated mitochondria from rat myocardium.

Journal: Doklady. Biochemistry and biophysics 20020101

Title: Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. II. Electrophysiological and fluorimetric studies.

Journal: Biochemical pharmacology 20011215

Title: Characteristics and superoxide-induced activation of reconstituted myocardial mitochondrial ATP-sensitive potassium channels.

Journal: Circulation research 20011207

Title: Anesthetic effects on mitochondrial ATP-sensitive K channel.

Journal: Anesthesiology 20011201

Title: Pharmacologically induced preconditioning with diazoxide: a novel approach to brain protection.

Journal: The Annals of thoracic surgery 20011201

Title: Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel.

Journal: Diabetes, obesity & metabolism 20011201

Title: Hyperinsulinaemic hypoglycaemia--leading symptom in a patient with congenital disorder of glycosylation Ia (phosphomannomutase deficiency).

Journal: Journal of inherited metabolic disease 20011201

Title: Opening of mitochondrial K(ATP) channels attenuates the ouabain-induced calcium overload in mitochondria.

Journal: Circulation research 20011109

Title: Mitochondrial ATP-sensitive potassium channels attenuate matrix Ca(2+) overload during simulated ischemia and reperfusion: possible mechanism of cardioprotection.

Journal: Circulation research 20011109

Title: Management of hyperinsulinemia with diazoxide in an elderly hemodialysis patient.

Journal: Nephron 20011101

Title: Mitochondrial K(ATP) channel as an end effector of cardioprotection during late preconditioning: triggering role of nitric oxide.

Journal: Journal of molecular and cellular cardiology 20011101

Title: The potential antidiabetic activity of some alpha-2 adrenoceptor antagonists.

Journal: Pharmacological research 20011101

Title: Mitochondrial ATP-sensitive channel opener does not induce vascular preconditioning, but potentiates the effect of a preconditioning ischemia on coronary reactive hyperemia in the anesthetized goat.

Journal: Pflugers Archiv : European journal of physiology 20011101

Title: Ischemic and pharmacological preconditioning in Girardi cells and C2C12 myotubes induce mitochondrial uncoupling.

Journal: Circulation research 20011026

Title: Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice.

Journal: American journal of physiology. Endocrinology and metabolism 20011001

Title: Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury.

Journal: American journal of physiology. Heart and circulatory physiology 20011001

Title: Glucose effects on gastric motility and tone evoked from the rat dorsal vagal complex.

Journal: The Journal of physiology 20011001

Title: The KATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidation.

Journal: British journal of pharmacology 20011001

Title: [Properties of KATP channels in hippocampal CA1 pyramidal neurons from adult rats].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20011001

Title: Ten years' experience of persistent hyperinsulinaemic hypoglycaemia of infancy.

Journal: Journal of paediatrics and child health 20011001

Title: Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism.

Journal: The Journal of biological chemistry 20010921

Title: Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain.

Journal: The Journal of biological chemistry 20010907

Title: Amino acids and insulin are both required to regulate assembly of the eIF4E. eIF4G complex in rat skeletal muscle.

Journal: American journal of physiology. Endocrinology and metabolism 20010901

Title: Mitochondrial K(ATP) channel activation reduces anoxic injury by restoring mitochondrial membrane potential.

Journal: American journal of physiology. Heart and circulatory physiology 20010901

Title: Hepatothermic therapy of obesity: rationale and an inventory of resources.

Journal: Medical hypotheses 20010901

Title: Hyperinsulinism and hyperammonemia syndrome: report of twelve unrelated patients.

Journal: Pediatric research 20010901

Title: Contribution of both the sarcolemmal K(ATP) and mitochondrial K(ATP) channels to infarct size limitation by K(ATP) channel openers: differences from preconditioning in the role of sarcolemmal K(ATP) channels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010901

Title: Diazoxide induced cardioprotection: what comes first, K(ATP) channels or reactive oxygen species?

Journal: Cardiovascular research 20010901

Title: Mitochondrial K(ATP) channel opening protects a human atrial-derived cell line by a mechanism involving free radical generation.

Journal: Cardiovascular research 20010901

Title: Synthesis and characterization of a quinolinonic compound activating ATP-sensitive K(+) channels in endocrine and smooth muscle tissues.

Journal: British journal of pharmacology 20010901

Title: Lidocaine and mexiletine inhibit mitochondrial oxidation in rat ventricular myocytes.

Journal: Anesthesiology 20010901

Title: [Activation of ATP-sensitive K+ channels by ADP and K+ channel openers: homology model of sulfonylurea receptor carboxyl-termini].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010901

Title: Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarction.

Journal: Basic research in cardiology 20010901

Title: Incorporation of sulfonylurea into N-isopropylacrylamide as an extracellular matrix for an artificial pancreas.

Journal: Bioscience, biotechnology, and biochemistry 20010901

Title: Effects of bezafibrate on beta-cell function of rat pancreatic islets.

Journal: European journal of pharmacology 20010831

Title: Modulation of islet ATP content by inhibition or stimulation of the Na(+)/K(+) pump.

Journal: European journal of pharmacology 20010824

Title: Original 2-alkylamino-6-halogenoquinazolin-4(3H)-ones and K(ATP) channel activity.

Journal: Journal of medicinal chemistry 20010802

Title: Laparoscopic pancreatectomy for persistent hyperinsulinemic hypoglycemia of infancy.

Journal: Surgical endoscopy 20010801

Title: ATP-sensitive K+ channels and cellular actions of morphine in periaqueductal gray slices of neonatal and adult rats.

Journal: The Journal of pharmacology and experimental therapeutics 20010801

Title: Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion.

Journal: The Journal of clinical investigation 20010801

Title: Acute insulin responses to leucine in children with the hyperinsulinism/hyperammonemia syndrome.

Journal: The Journal of clinical endocrinology and metabolism 20010801

Title: Sulfonylurea receptors inhibit the epithelial sodium channel (ENaC) by reducing surface expression.

Journal: Pflugers Archiv : European journal of physiology 20010801

Title: Inhibition of large-conductance calcium-activated potassium channel by 2-methoxyestradiol in cultured vascular endothelial (HUV-EC-C) cells.

Journal: The Journal of membrane biology 20010801

Title: Increased calcium vulnerability of senescent cardiac mitochondria: protective role for a mitochondrial potassium channel opener.

Journal: Mechanisms of ageing and development 20010731

Title: Phenylcyanoguanidines as inhibitors of glucose-induced insulin secretion from beta cells.

Journal: Bioorganic & medicinal chemistry letters 20010709

Title: Downregulation of protein kinase C inhibits activation of mitochondrial K(ATP) channels by diazoxide.

Journal: Circulation 20010703

Title: Distinct effect of diazoxide on insulin secretion stimulated by protein kinase A and protein kinase C in rat pancreatic islets.

Journal: Diabetes research and clinical practice 20010701

Title: Oral agents for the treatment of type 2 diabetes mellitus: pharmacology, toxicity, and treatment.

Journal: Annals of emergency medicine 20010701

Title: Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress.

Journal: Journal of neurophysiology 20010701

Title: Effect on insulin release of compounds structurally related to the potassium-channel opener 7-chloro-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide (BPDZ 73): introduction of heteroatoms on the 3-alkylamino side chain of the benzothiadiazine 1,1-dioxide ring.

Journal: The Journal of pharmacy and pharmacology 20010701

Title: Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide.

Journal: Circulation 20010626

Title: Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells.

Journal: Circulation research 20010622

Title: Role of intracellular Na(+) kinetics in preconditioned rat heart.

Journal: Circulation research 20010608

Title: A novel enhancer of insulinotrophic action by high glucose (JTT-608) stimulates insulin secretion from pancreatic beta-cells via a new cellular mechanism.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: Glucose-regulated pulsatile insulin release from mouse islets via the K(ATP) channel-independent pathway.

Journal: European journal of endocrinology 20010601

Title: Diazoxide effects on hypothalamic and extra-hypothalamic NPY content in Zucker rats.

Journal: Peptides 20010601

Title: Transient hyperinsulinism in an asphyxiated newborn infant with hypoglycemia.

Journal: American journal of perinatology 20010601

Title: Store-operated influx of Ca(2+) in pancreatic beta-cells exhibits graded dependence on the filling of the endoplasmic reticulum.

Journal: Journal of cell science 20010601

Title: When it is more than transient neonatal hypoglycemia: hyperinsulinemia--a case study challenge.

Journal: Neonatal network : NN 20010601

Title: Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress.

Journal: Journal of medicinal chemistry 20010524

Title: Preconditioning limits mitochondrial Ca(2+) during ischemia in rat hearts: role of K(ATP) channels.

Journal: American journal of physiology. Heart and circulatory physiology 20010501

Title: Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix.

Journal: Diabetes 20010501

Title: Chloride channels regulate HIT cell volume but cannot fully account for swelling-induced insulin secretion.

Journal: Diabetes 20010501

Title: The role of cyclic AMP in the pathogenesis of glucose desensitization in rat pancreatic islets.

Journal: Pancreas 20010501

Title: Opening of mitochondrial K(ATP) channels triggers cardioprotection. Are reactive oxygen species involved?

Journal: Circulation research 20010427

Title: Diazoxide-induced cardioprotection requires signaling through a redox-sensitive mechanism.

Journal: Circulation research 20010427

Title: Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction.

Journal: The Journal of biological chemistry 20010413

Title: Diabetes and hyperglycemia impair activation of mitochondrial K(ATP) channels.

Journal: American journal of physiology. Heart and circulatory physiology 20010401

Title: Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection.

Journal: The Annals of thoracic surgery 20010401

Title: Interaction of sulfonylurea-conjugated polymer with insulinoma cell line of MIN6 and its effect on insulin secretion.

Journal: Journal of biomedical materials research 20010401

Title: Restoration of Ca2+-inhibited oxidative phosphorylation in cardiac mitochondria by mitochondrial Ca2+ unloading.

Journal: Molecular and cellular biochemistry 20010401

Title: Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice.

Journal: Circulation research 20010330

Title: Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells.

Journal: The Journal of biological chemistry 20010302

Title: Methyl pyruvate initiates membrane depolarization and insulin release by metabolic factors other than ATP.

Journal: The Biochemical journal 20010301

Title: Oxytocin antagonist disrupts hypotension-evoked renin secretion and other responses in conscious rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010301

Title: Pituitary adenylate cyclase-activating polypeptide activates K(ATP) current in rat atrial myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20010301

Title: Neurologic outcomes of 90 neonates and infants with persistent hyperinsulinemic hypoglycemia.

Journal: Pediatrics 20010301

Title: Continuous infusion of glucagon induces severe hyponatremia and thrombocytopenia in a premature neonate.

Journal: Pediatrics 20010301

Title: Characterization of secretory and morphologic properties of primary cultured endocrine cells from porcine pancreata.

Journal: Pancreas 20010301

Title: Diazoxide, a K(ATP) opener, accelerates restitution of ethanol or indomethacin-induced gastric ulceration in rats independent of polyamines.

Journal: Journal of gastroenterology and hepatology 20010301

Title: Failure to precondition pathological human myocardium.

Journal: Journal of the American College of Cardiology 20010301

Title: Mitochondrial ATP-sensitive K+ channels play a role in cardioprotection by Na+-H+ exchange inhibition against ischemia/reperfusion injury.

Journal: Journal of the American College of Cardiology 20010301

Title: Potassium channel openers depolarize hippocampal mitochondria.

Journal: Brain research 20010216

Title: Involvement of K(ATP) channels in diethylstilbestrol-induced relaxation in rat aorta.

Journal: European journal of pharmacology 20010209

Title: Bioenergetic consequences of opening the ATP-sensitive K(+) channel of heart mitochondria.

Journal: American journal of physiology. Heart and circulatory physiology 20010201

Title: Pharmacological comparison of native mitochondrial K(ATP) channels with molecularly defined surface K(ATP) channels.

Journal: Molecular pharmacology 20010201

Title: Diazoxide protects mitochondria from anoxic injury: implications for myopreservation.

Journal: The Journal of thoracic and cardiovascular surgery 20010201

Title: [Cardioprotective mechanism of ischemic preconditioning is impaired by postinfarct ventricular remodeling through angiotensin II type 1 receptor activation].

Journal: Journal of cardiology 20010201

Title: Effects of glucose and amino acids on free ADP in betaHC9 insulin-secreting cells.

Journal: Diabetes 20010201

Title: Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.

Journal: Diabetes 20010201

Title: Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.

Journal: Diabetes 20010201

Title: Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan.

Journal: Diabetes 20010201

Title: Overstimulation and beta-cell function.

Journal: Diabetes 20010201

Title: [Personal experience with surgical treatment of insulinoma].

Journal: Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti 20010201

Title: Downregulation of the voltage-dependent calcium channel (VDCC) beta-subunit mRNAs in pancreatic islets of type 2 diabetic rats.

Journal: Biochemical and biophysical research communications 20010126

Title: K(ATP) channel blockers selectively interact with A(1)-adenosine receptor mediated modulation of acetylcholine release in the rat hippocampus.

Journal: Brain research 20010119

Title: Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells.

Journal: The Journal of biological chemistry 20010112

Title: Direct activation of mitochondrial K(ATP) channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts.

Journal: Cardiovascular research 20010101

Title: Dual roles of mitochondrial K(ATP) channels in diazoxide-mediated protection in isolated rabbit hearts.

Journal: American journal of physiology. Heart and circulatory physiology 20010101

Title: Role of mitochondrial and sarcolemmal K(ATP) channels in ischemic preconditioning of the canine heart.

Journal: American journal of physiology. Heart and circulatory physiology 20010101

Title: Acute hypertension inhibits thirst stimulated by ANG II, hyperosmolality, or hypovolemia in rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010101

Title: Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes.

Journal: Journal of molecular and cellular cardiology 20010101

Title: Ischemic preconditioning with opening of mitochondrial adenosine triphosphate-sensitive potassium channels or Na/H exchange inhibition: which is the best protective strategy for heart transplants?

Journal: The Journal of thoracic and cardiovascular surgery 20010101

Title: Insulin autoimmune syndrome: the second Dutch case.

Journal: The Netherlands journal of medicine 20010101

Title: Diazoxide and trimethaphan used?

Journal: Chest 20010101

Title: Mitochondrial ATP-sensitive potassium channel plays a dominant role in ischemic preconditioning of rabbit heart.

Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20010101

Title: Intracellular potassium and chloride channels: an update.

Journal: Acta biochimica Polonica 20010101

Title: Disopyramide and its metabolite enhance insulin release from clonal pancreatic beta-cells by blocking K(ATP) channels.

Journal: Cardiovascular drugs and therapy 20010101

Title: Consequences of haemolysis without haptoglobin.

Journal: Redox report : communications in free radical research 20010101

Title: Cholelithiasis in a newborn following treatment with the somatostatin analogue octreotide.

Journal: European journal of pediatrics 20000701

Title: Dual regulation of leptin secretion: intracellular energy and calcium dependence of regulated pathway.

Journal: American journal of physiology. Endocrinology and metabolism 20000501

Title: Drugs for rapid treatment of very high blood pressure during pregnancy.

Journal: The Cochrane database of systematic reviews 20000101

Title: Modulation of beta-cell ouabain-sensitive 86Rb+ influx (Na+/K+ pump) by D-glucose, glibenclamide or diazoxide.

Journal: International journal of experimental diabetes research 20000101

Title: NADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretion.

Journal: The Journal of biological chemistry 19990903

Title: PIP2 and PIP as determinants for ATP inhibition of KATP channels.

Journal: Science (New York, N.Y.) 19981106

Title: Glucose regulation of islet amyloid polypeptide gene expression in rat pancreatic islets.

Journal: The American journal of physiology 19970401

Title: Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel.

Journal: The Journal of physiology 19970315

Title: A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel.

Journal: The Journal of biological chemistry 19961004

Title: Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.

Journal: Science (New York, N.Y.) 19951117

Title: Involvement of potassium and calcium channels at the locus coeruleus in fentanyl-induced muscular rigidity in the rat.

Journal: Neuroscience letters 19951027

Title: Effect of four potassium channel agonists on bupivacaine-induced toxicity in mice.

Journal: Life sciences 19950101

Title: Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19930901

Title: Drug-induced diabetes.

Journal: Bailliere's clinical endocrinology and metabolism 19921001

Title: Hypertrophic cardiomyopathy after prolonged diazoxide therapy for hyperinsulinemic hypoglycemia.

Journal: The Journal of pediatrics 19910601

Title: Relationship between thirst and diazoxide-induced hypotension in rats.

Journal: The American journal of physiology 19900801

Title: Complications of diazoxide treatment in persistent neonatal hyperinsulinism.

Journal: Archives of disease in childhood 19891001

Title: Reversal by hypothermia of vasodilator-induced tachycardia in anesthetized rats.

Journal: Archives internationales de pharmacodynamie et de therapie 19870801

Title: Complications of diazoxide in the treatment of nesidioblastosis.

Journal: Archives of disease in childhood 19850101

Title: Leucine-induced hypoglycemia in a family: effect of diphenylhydantoin, oxprenolol, and diazoxide.

Journal: Hormone research 19840101

Title: Effect of diazoxide-induced hypotension on cerebral blood flow in hypertensive rats.

Journal: European journal of clinical investigation 19830601

Title: Vasodilators in the treatment of hypertension.

Journal: Comprehensive therapy 19821101

Title: Treatment of hypertensive emergencies of pregnancy.

Journal: Clinical pharmacy 19820101

Title: Hazards of diazoxide in pulmonary hypertension.

Journal: British heart journal 19811001

Title: [Prolonged hypotension after the first dose of atenolol (author's transl)].

Journal: Medicina clinica 19810425

Title: Studies in the rat on endralazine, a new antihypertensive drug structurally related to hydralazine.

Journal: Clinical and experimental pharmacology & physiology 19810101

Title: Blindness and malignant hypertension.

Journal: Lancet (London, England) 19791013

Title: Individual titration of diazoxide dosage in the treatment of severe hypertension.

Journal: The American journal of cardiology 19790301

Title: Comparison of effects on cerebral blood flow of rapid reduction in systemic arterial pressure by diazoxide and labetalol in hypertensive patients: preliminary findings.

Journal: British journal of clinical pharmacology 19790101

Title: Plasma renin and angiotensin II measurement in hypertensive and normal subjects: correlation of basal and stimulated states.

Journal: The Journal of clinical endocrinology and metabolism 19770701

Title: Hypotension and bradycardia following diazoxide and hydralazine therapy.

Journal: JAMA 19770606

Title: Orthostatic hypotension due to prazosin.

Journal: Lancet (London, England) 19770212

Title: Hazards in antihypertension therapy.

Journal: Annals of internal medicine 19770101

Title: Haemodynamic effects of prazosin.

Journal: Archives internationales de pharmacodynamie et de therapie 19761201

Title: Letter: Diazoxide and myocardial ischemia.

Journal: Annals of internal medicine 19760901

Title: Angina-like syndrome with diazoxide therapy for hypertensive crisis.

Journal: Annals of internal medicine 19760601

Title: Effect of antidiuretic drugs in rats with lithium-induced polyuria.

Journal: Acta pharmacologica et toxicologica 19760201

Title: Side effects of diazoxide.

Journal: JAMA 19760119

Title: Development and management of extrapyramidal symptoms in hypertensive patients treated with diazoxide.

Journal: American heart journal 19750301

Title: Oral diazoxide in uncontrolled malignant hypertension.

Journal: The Medical journal of Australia 19741026

Title: Development of extrapyramidal symptoms in hypertensive patients treated with diazoxide.

Journal: British medical journal 19730901

Title: Diazoxide.

Journal: JAMA 19730813

Title: Intravenous diazoxide in the treatment of severe pre-eclamptic toxaemia and eclampsia.

Journal: The Australian & New Zealand journal of obstetrics & gynaecology 19730801

Title: [Hyperglycemic coma without ketoacidosis in 2 hypertensive patients treated with intravenous diazoxide].

Journal: La Nouvelle presse medicale 19720909

Title: Treatment of hypertension in infancy with diazoxide: report of a case with arrhythmia as a complications of therapy.

Journal: The Journal of pediatrics 19720401

Title: Hyperosmolar nonketotic coma associated with diazoxide therapy for hypoglycemia.

Journal: The Journal of pediatrics 19710301

Title: Management of severe hypertension with intravenous injections of diazoxide.

Journal: The American journal of cardiology 19691201

Title: Pluriglandular syndrome with hyperinsulinism. Cardiomegaly as a possible complication of diazoxide therapy.

Journal: Proceedings of the Royal Society of Medicine 19681201

Title: Toxic effects of a chlorothiazide-diazoxide combination on adipose tissue and kidneys of intact rats.

Journal: Diabetologia 19680601

Title: The therapeutic application of diazoxide in pediatric hypoglycemic states.

Journal: Annals of the New York Academy of Sciences 19680411

Title: Experimental and clinical studies with diazoxide.

Journal: Annals of the New York Academy of Sciences 19680411

Title: Influence of drugs, implanted into the hypothalamus, on the water consumption of rats.

Journal: The Journal of pharmacology and experimental therapeutics 19680101

Title: Coetzee WA, et al. Multiplicity of effectors of the cardioprotective agent, diazoxide. Pharmacol Ther. 2013 Nov;140(2):167-75.

Title: Virgili N, et al. K(ATP) channel opener diazoxide prevents neurodegeneration: a new mechanism of action viaantioxidative pathway activation. PLoS One. 2013 Sep 11;8(9):e75189.

Title: Wu H, et al. Diazoxide Attenuates Postresuscitation Brain Injury in a Rat Model of Asphyxial Cardiac Arrest by Opening Mitochondrial ATP-Sensitive Potassium Channels. Biomed Res Int. 2016;2016:1253842.

Title: Chowdhury UR, et al. ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure in vivo. Invest Ophthalmol Vis Sci. 2013 Jul 22;54(7):4892-9.

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