Home Amines 366-80-3
366-80-3,MFCD00242937
Catalog No.:AA01X3HT

366-80-3 | Methanesulfonamide, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-, hydrochloride (1:2)

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01X3HT
Chemical Name:
Methanesulfonamide, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-, hydrochloride (1:2)
CAS Number:
366-80-3
Molecular Formula:
C12H21ClN2O3S
Molecular Weight:
308.8247
MDL Number:
MFCD00242937
SMILES:
CC(NCC(c1ccc(cc1)NS(=O)(=O)C)O)C.Cl
Properties
Computed Properties
 
Complexity:
330  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Why Can dl-Sotalol Prolong the QT Interval In Vivo Despite Its Weak Inhibitory Effect on hERG K(+) Channels In Vitro? Electrophysiological and Pharmacokinetic Analysis with the Halothane-Anesthetized Guinea Pig Model.

Journal: Cardiovascular toxicology 20160401

Title: Discovery of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors (part I).

Journal: European journal of medicinal chemistry 20140623

Title: Excimer formation in inclusion complexes of β-cyclodextrin with salbutamol, sotalol and atenolol: spectral and molecular modeling studies.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001

Title: Beneficial cardiac effects of cicletanine in conscious rabbits with metabolic syndrome.

Journal: Journal of cardiovascular pharmacology 20120801

Title: Sotalol permeability in cultured-cell, rat intestine, and PAMPA system.

Journal: Pharmaceutical research 20120701

Title: Concurrent supplement of estradiol and progesterone reduces the cardiac sensitivity to D,L-sotalol-induced arrhythmias in ovariectomized rabbits.

Journal: Journal of cardiovascular pharmacology and therapeutics 20120601

Title: Effectiveness of sotalol as first-line therapy for fetal supraventricular tachyarrhythmias.

Journal: The American journal of cardiology 20120601

Title: [Practical ECG problems. Torsade de pointes in an elderly patient].

Journal: Revue medicale suisse 20120509

Title: Characterization of A-935142, a hERG enhancer, in the presence and absence of standard hERG blockers.

Journal: Life sciences 20120420

Title: Wide QRS Tachycardia in a young patient.

Journal: Archives of internal medicine 20120409

Title: Diverse modulating effects of estradiol and progesterone on the monophasic action potential duration in Langendorff-perfused female rabbit hearts.

Journal: Fundamental & clinical pharmacology 20120401

Title: Acute inhibition of the Na(+)/Ca(2+) exchanger reduces proarrhythmia in an experimental model of chronic heart failure.

Journal: Heart rhythm 20120401

Title: Role of sodium/calcium exchange in heart failure-induced arrhythmias: a potential therapeutic target.

Journal: Heart rhythm 20120401

Title: Long-term omega-3 polyunsaturated fatty acid supplementation reduces the recurrence of persistent atrial fibrillation after electrical cardioversion.

Journal: Heart rhythm 20120401

Title: Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol.

Journal: Circulation. Arrhythmia and electrophysiology 20120401

Title: Gender differences in cardiac repolarization following intravenous sotalol administration.

Journal: Journal of cardiovascular pharmacology and therapeutics 20120301

Title: Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations.

Journal: Heart rhythm 20120301

Title: Comparative pharmacophysiology of vernakalant, ranolazine, and d-sotalol in canine pulmonary vein sleeve preparations: new flavors or same old taste?

Journal: Heart rhythm 20120301

Title: Pharmacophore modeling for hERG channel facilitation.

Journal: Biochemical and biophysical research communications 20120203

Title: Transplacental fetal therapy for junctional ectopic tachycardia.

Journal: Journal of clinical ultrasound : JCU 20120201

Title: Heart rate variability response to standing in men and women receiving d,l-sotalol following coronary artery bypass graft surgery.

Journal: Biological research for nursing 20120101

Title: Cardiac sarcoidosis masquerading as arrhythmogenic right ventricular cardiomyopathy.

Journal: Heart, lung & circulation 20120101

Title: Electrophysiologic profile of dronedarone on the ventricular level: beneficial effect on postrepolarization refractoriness in the presence of rapid phase 3 repolarization.

Journal: Journal of cardiovascular pharmacology 20120101

Title: Intraosseous infusion is unreliable for adenosine delivery in the treatment of supraventricular tachycardia.

Journal: Pediatric emergency care 20120101

Title: In vitro model for assessing arrhythmogenic properties of drugs based on high-resolution impedance measurements.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: Conventional QT variability measurement vs. template matching techniques: comparison of performance using simulated and real ECG.

Journal: PloS one 20120101

Title: [Atrial fibrillation after coronary artery bypass surgery: possibilities of prevention].

Journal: Srpski arhiv za celokupno lekarstvo 20120101

Title: Combined blockade of early and late activated atrial potassium currents suppresses atrial fibrillation in a pig model of obstructive apnea.

Journal: Heart rhythm 20111201

Title: Pharmacological treatment of atrial fibrillation: what does it take?

Journal: Heart rhythm 20111201

Title: Guidelines for the diagnosis and management of arrhythmogenic right ventricular cardiomyopathy.

Journal: Heart, lung & circulation 20111201

Title: Ranolazine reduces ventricular tachycardia burden and ICD shocks in patients with drug-refractory ICD shocks.

Journal: Pacing and clinical electrophysiology : PACE 20111201

Title: One-year treatment persistence and potential adverse events among patients with atrial fibrillation treated with amiodarone or sotalol: a retrospective claims database analysis.

Journal: Clinical therapeutics 20111101

Title: Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized multicenter study.

Journal: Circulation 20111018

Title: High-dose sotalol is safe and effective in neonates and infants with refractory supraventricular tachyarrhythmias.

Journal: Pediatric cardiology 20111001

Title: A new mechanism preventing proarrhythmia in chronic heart failure: rapid phase-III repolarization explains the low proarrhythmic potential of amiodarone in contrast to sotalol in a model of pacing-induced heart failure.

Journal: European journal of heart failure 20111001

Title: Modulation of the late sodium current by ATX-II and ranolazine affects the reverse use-dependence and proarrhythmic liability of IKr blockade.

Journal: British journal of pharmacology 20110901

Title: The efficacy of sotalol in preventing postoperative atrial fibrillation: a meta-analysis.

Journal: The American journal of medicine 20110901

Title: Assessment of sotalol prescribing in a community hospital: opportunities for clinical pharmacist involvement.

Journal: The International journal of pharmacy practice 20110801

Title: First direct comparison of the late sodium current blocker ranolazine to established antiarrhythmic agents in an ischemia/reperfusion model.

Journal: Journal of cardiovascular pharmacology and therapeutics 20110601

Title: I(Kr) vs. I(Ks) blockade and arrhythmogenicity in normoxic rabbit Purkinje fibers: does it really make a difference?

Journal: Fundamental & clinical pharmacology 20110601

Title: Granuloma annulare of the palms.

Journal: Dermatology online journal 20110515

Title: A novel mutation in the KCNH2 gene associated with short QT syndrome.

Journal: Journal of molecular and cellular cardiology 20110301

Title: Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301

Title: Mixed treatment comparisons for atrial fibrillation: evidence network or bewildering entanglement?

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301

Title: Occurrence and removal of pharmaceuticals and hormones through drinking water treatment.

Journal: Water research 20110101

Title: A comparison of long-standing implantable cardioverter-defibrillator patients with and without appropriate therapy for ventricular arrhythmias: impact of a widening QRS.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110101

Title: Microminipig, a non-rodent experimental animal optimized for life science research: in vivo proarrhythmia models of drug-induced long QT syndrome: development of chronic atrioventricular block model of microminipig.

Journal: Journal of pharmacological sciences 20110101

Title: Canadian Cardiovascular Society atrial fibrillation guidelines 2010: rate and rhythm management.

Journal: The Canadian journal of cardiology 20110101

Title: Cardiovascular and respiratory safety pharmacology in Göttingen minipigs: Pharmacological characterization.

Journal: Journal of pharmacological and toxicological methods 20110101

Title: [Appearance of ECG signs of the Brugada syndrome during therapy with class 1C antiarrhythmic drug ethacizine].

Journal: Kardiologiia 20110101

Title: Atrial fibrillation (acute onset).

Journal: BMJ clinical evidence 20110101

Title: Late proarrhythmia on sotalol therapy triggered by emotional stress.

Journal: Kardiologia polska 20110101

Title: 'Zone of avoidance': RR interval distribution in tachograms, histograms, and Poincaré plots of a Boxer dog.

Journal: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology 20101201

Title: Augmenting maintenance of sinus rhythm in the control of atrial fibrillation by antiarrhythmic drug combinations.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Sotalol-induced torsades de pointes precipitated during treatment with oseltamivir for H1N1 influenza.

Journal: Heart rhythm 20101001

Title: Extraction and preconcentration of beta-blockers in human urine for analysis with high performance liquid chromatography by means of carrier-mediated liquid phase microextraction.

Journal: Talanta 20100815

Title: Combination therapy with mexiletine and sotalol suppresses inherited ventricular arrhythmias in German shepherd dogs better than mexiletine or sotalol monotherapy: a randomized cross-over study.

Journal: Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology 20100801

Title: Covariate analysis of QTc and T-wave morphology: new possibilities in the evaluation of drugs that affect cardiac repolarization.

Journal: Clinical pharmacology and therapeutics 20100701

Title: Rhythm control agents and adverse events in patients with atrial fibrillation.

Journal: International journal of clinical practice 20100701

Title: Pharmacologic prophylaxis of postoperative atrial fibrillation in patients undergoing cardiac surgery: beyond beta-blockers.

Journal: Pharmacotherapy 20100701

Title: First time and repeat cardioversion of atrial tachyarrhythmias - a comparison of outcomes.

Journal: International journal of clinical practice 20100701

Title: Highly sensitive transient isotachophoresis sample stacking coupling with capillary electrophoresis-amperometric detection for analysis of doping substances.

Journal: Talanta 20100615

Title: Mortality and safety of catheter ablation for antiarrhythmic drug-refractory ventricular tachycardia in elderly patients with coronary artery disease.

Journal: Heart rhythm 20100601

Title: ECG of the month. Arrhythmogenic right ventricular cardiomyopathy in a Boxer.

Journal: Journal of the American Veterinary Medical Association 20100501

Title: Autonomic, behavioral, and neural analyses of mild conditioned negative affect in marmosets.

Journal: Behavioral neuroscience 20100401

Title: Atrial fibrillation degenerates into ventricular fibrillation.

Journal: Journal of the American College of Cardiology 20100309

Title: Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes.

Journal: Stem cell research 20100301

Title: Massive ingestion of cardiac drugs: toxicokinetic aspects of digoxin and sotalol during hemofiltration.

Journal: Clinical toxicology (Philadelphia, Pa.) 20100301

Title: Physician stated atrial fibrillation management in light of treatment guidelines: data from an international, observational prospective survey.

Journal: Clinical cardiology 20100301

Title: Sotalol and a broken heart.

Journal: Journal of cardiovascular electrophysiology 20100201

Title: Reversible vestibular dysfunction secondary to sotalol use.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20100101

Title: Control of branchial artery tone in fish: effects of environmental temperature and phylogeny.

Journal: Physiological and biochemical zoology : PBZ 20100101

Title: ECG of the Month. Atrial flutter.

Journal: Journal of the American Veterinary Medical Association 20100101

Title: The time course of new T-wave ECG descriptors following single- and double-dose administration of sotalol in healthy subjects.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20100101

Title: Human and murine embryonic stem cell-derived cardiomyocytes serve together as a valuable model for drug safety screening.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101

Title: Developing a safe intravenous sotalol dosing regimen.

Journal: American journal of therapeutics 20100101

Title: [Atrial fibrillation in patients with type 2 diabetes mellitus: specific features of development and antirecurrence therapy].

Journal: Kardiologiia 20100101

Title: QT prolongation and serum sotalol concentration are highly correlated following intravenous and oral sotalol.

Journal: Cardiology 20100101

Title: A new ECG biomarker for drug toxicity: a combined signal processing and computational modeling study.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20100101

Title: Gastroenteritis with severe consequences: a case of sotalol-induced torsades de pointes.

Journal: Acta cardiologica 20091201

Title: [79-year-old patient with paroxysmal artial fibrillation and syncope].

Journal: Deutsche medizinische Wochenschrift (1946) 20091101

Title: Challenge. What is your diagnosis? Answer. Primary nodal diffuse large B-cell lymphoma with secondary cutaneous involvement.

Journal: The American Journal of dermatopathology 20091001

Title: Intrapericardial delivery of amiodarone and sotalol: atrial transmural drug distribution and electrophysiological effects.

Journal: Journal of cardiovascular pharmacology 20091001

Title: d,l-Sotalol reverses abbreviated atrial refractoriness and prevents promotion of atrial fibrillation in a canine model with left ventricular dysfunction induced by atrial tachypacing.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20091001

Title: Novelty-induced arousal enhances memory for cued classical fear conditioning: interactions between peripheral adrenergic and brainstem glutamatergic systems.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20091001

Title: Famotidine neither affects action potential parameters nor inhibits human ether-a-go-go-related gene (hERG) K+ current.

Journal: The Journal of toxicological sciences 20091001

Title: Termination of recurrent ventricular tachycardia by continuous positive airway pressure ventilation.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20091001

Title: [Effectiveness of D,L-sotalol in post-ablative atrial arrhythmias in patients with atrial fibrillation treated with radiofrequency ablation].

Journal: Orvosi hetilap 20090906

Title: Prenatal management with digoxin and sotalol combination for fetal supraventricular tachycardia: case report and review of literature.

Journal: Indian journal of medical sciences 20090901

Title: Atrial tachycardias in young adults and adolescents with congenital heart disease: conversion using single dose oral sotalol.

Journal: International journal of cardiology 20090821

Title: Efficacy of antiarrhythmic drugs in arrhythmogenic right ventricular cardiomyopathy: a report from the North American ARVC Registry.

Journal: Journal of the American College of Cardiology 20090811

Title: Empiric antiarrhythmic drug therapy in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia: pragmatism or anachronism?

Journal: Journal of the American College of Cardiology 20090811

Title: Effect of the nature of the single-isomer anionic CD and the BGE composition on the enantiomeric separation of beta-blockers in NACE.

Journal: Electrophoresis 20090801

Title: [Life-threatening ventricular arrhythmia during simultaneous administration of propafenone and sotatol].

Journal: Kardiologia polska 20090801

Title: Simultaneous RP-HPLC determination of sotalol, metoprolol, alpha-hydroxymetoprolol, paracetamol and its glucuronide and sulfate metabolites in human urine.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090601

Title: [Effects of chronic amiodarone therapy on L-type calcium current recovery and action potential duration of rabbit ventricular myocytes].

Journal: Zhonghua xin xue guan bing za zhi 20090601

Title: Systemic propranolol acts centrally to reduce conditioned fear in rats without impairing extinction.

Journal: Biological psychiatry 20090515

Title: Cost of hospital admission for antiarrhythmic drug initiation in atrial fibrillation.

Journal: The Annals of pharmacotherapy 20090501

Title: Implantable cardioverter defibrillator therapy for patients with chronic Chagas' disease: a randomized trial may not be necessary in high-risk patients.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090401

Title: Adverse event in response to aliskiren.

Journal: Southern medical journal 20090401

Title: Aliskiren-induced QT interval prolongation.

Journal: Southern medical journal 20090401

Title: Post induction arrhythmia in a renal patient: an unexpected risk factor.

Journal: Anaesthesia 20090401

Title: Dispersion of repolarization and arrhythmogenesis.

Journal: Heart rhythm 20090401

Title: Restitution, heterogeneity and unidirectional conduction block: New roles for old players.

Journal: Heart rhythm 20090401

Title: [Next cardioversion or RF ablation in professional driver with recurrent typical atrial flutter and MAS syndromes].

Journal: Kardiologia polska 20090301

Title: Recurrent syncope associated with paroxysmal supraventricular tachycardia in a Devon Rex cat diagnosed by implantable loop recorder.

Journal: Journal of feline medicine and surgery 20090201

Title: Effects of intrapericardial sotalol and flecainide on transmural atrial electrophysiology and atrial fibrillation.

Journal: Journal of cardiovascular electrophysiology 20090201

Title: Systematic electrocardioversion for atrial fibrillation and role of antiarrhythmic drugs: a substudy of the SAFE-T trial.

Journal: Heart rhythm 20090201

Title: In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes.

Journal: Stem cells and development 20090101

Title: Mortality and reinfarction among patients using different beta-blockers for secondary prevention after a myocardial infarction.

Journal: Cardiology 20090101

Title: Halothane-anaesthetized, closed-chest, guinea-pig model for assessment of drug-induced QT-interval prolongation.

Journal: Basic & clinical pharmacology & toxicology 20090101

Title: Baseline values and sotalol-induced changes of ventricular repolarization duration, heterogeneity, and instability in patients with a history of drug-induced torsades de pointes.

Journal: Journal of clinical pharmacology 20090101

Title: d,l-Sotalol at therapeutic concentrations facilitates the occurrence of long-lasting non-stationary reentry during ventricular fibrillation in isolated rabbit hearts.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20090101

Title: Calculation of QT shift in non clinical safety pharmacology studies.

Journal: Journal of pharmacological and toxicological methods 20090101

Title: Automatic extraction of ECG strips from continuous 12-lead holter recordings for QT analysis at prescheduled versus optimized time points.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20090101

Title: Automated QT analysis that learns from cardiologist annotations.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20090101

Title: [Effect of hypotensive therapy on metalloproteinase activity of the blood in patients with arterial hypertension].

Journal: Kardiologiia 20090101

Title: Evaluation of drug-induced QT prolongation in a halothane-anesthetized monkey model: effects of sotalol.

Journal: Journal of pharmacological and toxicological methods 20090101

Title: Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy.

Journal: Cardiology journal 20090101

Title: Effect of compound plate composition on measurement of hERG current IC(50) using PatchXpress.

Journal: Journal of pharmacological and toxicological methods 20090101

Title: Sotalol as adjunctive therapy to implantable cardioverter-defibrillators in heart failure patients.

Journal: Congestive heart failure (Greenwich, Conn.) 20090101

Title: Identifying drug-induced repolarization abnormalities from distinct ECG patterns in congenital long QT syndrome: a study of sotalol effects on T-wave morphology.

Journal: Drug safety 20090101

Title: Non-invasive telemetric electrocardiogram assessment in conscious beagle dogs.

Journal: Journal of pharmacological and toxicological methods 20090101

Title: [Current application of sotalol in treatment of pediatric cardiac arrhythmia].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20090101

Title: Prevalence of appropriate cardioverter-defibrillator shocks in 1038 consecutive patients with implantable cardioverter-defibrillators.

Journal: American journal of therapeutics 20090101

Title: Pharmacological enhancement of cardiac gap junction coupling prevents arrhythmias in canine LQT2 model.

Journal: Cell communication & adhesion 20090101

Title: Identify drug-induced T wave morphology changes by a cell-to-electrocardiogram model and validation with clinical trial data.

Journal: Journal of electrocardiology 20090101

Title: Efficacy and safety of sotalol for refractory tachyarrhythmias in congenital heart disease.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20081201

Title: Endoluminal norepinephrine inhibits smooth muscle activity of the pig pyeloureter by stimulation of beta-adrenoceptors without side effects.

Journal: Basic & clinical pharmacology & toxicology 20081101

Title: Electrochemically modulated liquid-liquid extraction of ionized drugs under physiological conditions.

Journal: Analytical chemistry 20081101

Title: Effects of procainamide and sotalol on restitution properties, dispersion of refractoriness, and ventricular fibrillation activation patterns in pigs.

Journal: Journal of cardiovascular electrophysiology 20081001

Title: Combination antiarrhythmic therapy: 1 + 1 > 2?

Journal: Journal of cardiovascular electrophysiology 20081001

Title: Absence of protective effect of renin-angiotensin system inhibitors on atrial fibrillation development: insights from the Canadian Trial of Atrial Fibrillation (CTAF).

Journal: The Canadian journal of cardiology 20080901

Title: Dose-response effects of sotalol on cardiovascular function in conscious, freely moving cynomolgus monkeys.

Journal: British journal of pharmacology 20080801

Title: Role of drug therapy for sustained ventricular tachyarrhythmias.

Journal: Cardiology clinics 20080801

Title: Treatment of fetal tachycardia.

Journal: Heart rhythm 20080801

Title: The Drug And Pace Health cliNical Evaluation (DAPHNE) study: a randomized trial comparing sotalol versus beta-blockers to treat symptomatic atrial fibrillation in patients with brady-tachycardia syndrome implanted with an antitachycardia pacemaker.

Journal: American heart journal 20080801

Title: Prediction of drug-induced QT interval prolongation in telemetered common marmosets.

Journal: The Journal of toxicological sciences 20080801

Title: Ask the doctor. When I was diagnosed with atrial fibrillation four years ago, my doctor put me on a calcium-channel blocker. A year or so later, after I had angioplasty and got a stent, my doctor switched me to twice-a-day sotalol. Now I feel tired all the time and have gained weight, even though I feel like I am eating less. Can this be from the sotalol?

Journal: Harvard heart letter : from Harvard Medical School 20080801

Title: Incidence and pathophysiology of atrioventricular block following mitral valve replacement and ring annuloplasty.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20080701

Title: [Sotalol prevents atrio-ventricular tachycardia but not atrial fibrillation with rapid ventricular response in a patient wiht WPW syndrome].

Journal: Kardiologia polska 20080701

Title: Drug-induced torsades de pointes: a review of the Swedish pharmacovigilance database.

Journal: Pharmacoepidemiology and drug safety 20080601

Title: Comparison of electropharmacological effects of bepridil and sotalol in halothane-anesthetized dogs.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080601

Title: [The comparison between the efficiency of different anti-arrhythmic agents in preventing postoperative atrial fibrillation after open heart surgery].

Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20080601

Title: Intravenous magnesium sulphate and sotalol for prevention of atrial fibrillation after coronary artery bypass surgery: a systematic review and economic evaluation.

Journal: Health technology assessment (Winchester, England) 20080601

Title: The effects of nifekalant hydrochloride on the QT dispersion after direct-current defibrillation.

Journal: Osaka city medical journal 20080601

Title: Quantitative performance of E-Scribe warehouse in detecting quality issues with digital annotated ECG data from healthy subjects.

Journal: Journal of clinical pharmacology 20080501

Title: Effects of pink grapefruit juice on QT variability in patients with dilated or hypertensive cardiomyopathy and in healthy subjects.

Journal: Translational research : the journal of laboratory and clinical medicine 20080501

Title: Can digoxin and sotalol therapy for fetal supraventricular tachycardia and hydrops be successful? A case report.

Journal: The Journal of reproductive medicine 20080501

Title: Atrial fibrillation pharmacotherapy after hospital discharge between 1995 and 2004: a shift towards beta-blockers.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20080401

Title: Sotalol unmasks susceptibility to drug-induced long QT syndrome and torsades de pointes.

Journal: International journal of cardiology 20080314

Title: Cardiogenic shock secondary to combination of diltiazem and sotalol.

Journal: Internal medicine journal 20080301

Title: Role of brain adrenoceptors in the corticortopin-releasing factor-induced central activation of sympatho-adrenomedullary outflow in rats.

Journal: Life sciences 20080227

Title: A randomized comparison of amiodarone and class IC antiarrhythmic drugs to treat atrial fibrillation in patients paced for sinus node disease: the Prevention Investigation and Treatment: A Group for Observation and Research on Atrial arrhythmias (PITAGORA) trial.

Journal: American heart journal 20080101

Title: Use of a combination of class III and class Ic antiarrhythmic agents in patients with electrical storm.

Journal: Pharmacotherapy 20080101

Title: Effects of antiarrhythmic drugs on inappropriate shocks in patients with implantable cardioverter defibrillators.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20080101

Title: [Circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation. Results of the APAF trial].

Journal: Kardiologiia 20080101

Title: Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart.

Journal: Journal of pharmacological and toxicological methods 20080101

Title: The Bix rule.

Journal: Heart & lung : the journal of critical care 20080101

Title: Investigating the effect of sotalol on the repolarization intervals in healthy young individuals.

Journal: Journal of electrocardiology 20080101

Title: Atrial fibrillation (acute onset).

Journal: BMJ clinical evidence 20080101

Title: Bifocal versus unifocal right atrial pacing under plasma level controlled sotalol to prevent atrial fibrillation in patients with symptomatic sinus bradycardia and paroxysmal atrial fibrillation.

Journal: Herzschrittmachertherapie & Elektrophysiologie 20071201

Title: In vitro effects of acute amiodarone and dronedarone on epicardial, endocardial, and M cells of the canine ventricle.

Journal: Journal of cardiovascular pharmacology and therapeutics 20071201

Title: Torsades de Pointes: a rare complication of an extra-adrenal pheochromocytoma.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20071201

Title: [Suicide attempt with sotalol: a proarrhythmic intoxication].

Journal: Nederlands tijdschrift voor geneeskunde 20071006

Title: Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation.

Journal: The American journal of medicine 20071001

Title: Analyses of dynamic beat-to-beat QT-TQ interval (ECG restitution) changes in humans under normal sinus rhythm and prior to an event of torsades de pointes during QT prolongation caused by sotalol.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20071001

Title: Measurements of blood pressure and electrocardiogram in conscious freely moving guineapigs: a model for screening QT interval prolongation effects.

Journal: Laboratory animals 20071001

Title: Contrasting time- and rate-based approaches for the assessment of drug-induced QT changes.

Journal: Journal of clinical pharmacology 20070901

Title: Monotherapy versus combination therapy with class III antiarrhythmic agents to attenuate transmural dispersion of repolarization: a potential risk factor for torsade de pointes.

Journal: Pharmacotherapy 20070901

Title: Effect of dl-sotalol on mortality and recurrence of ventricular tachyarrhythmias: ischemic compared to nonischemic cardiomyopathy.

Journal: Pacing and clinical electrophysiology : PACE 20070901

Title: Adjunctive therapy for recurrent ventricular tachycardia in patients with implantable cardioverter defibrillators.

Journal: Current cardiology reports 20070901

Title: Electrophysiologic actions of d,l-sotalol and GLG-V-13 in ischemically injured canine epicardium.

Journal: Journal of cardiovascular pharmacology 20070901

Title: [Pharmacological therapy for atrial fibrillation after cardiac surgery].

Journal: Kyobu geka. The Japanese journal of thoracic surgery 20070701

Title: Evidence that pharmacological strategies lack efficacy for the prevention of sudden death in hypertrophic cardiomyopathy.

Journal: Heart (British Cardiac Society) 20070601

Title: Reduction of dispersion of repolarization and prolongation of postrepolarization refractoriness explain the antiarrhythmic effects of quinidine in a model of short QT syndrome.

Journal: Journal of cardiovascular electrophysiology 20070601

Title: Quinidine in short QT syndrome: an old drug for a new disease.

Journal: Journal of cardiovascular electrophysiology 20070601

Title: Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.

Journal: Heart rhythm 20070501

Title: Torsades de pointes with a severely prolonged QT interval induced by an initial low dose sotalol intake.

Journal: International journal of cardiology 20070404

Title: Analysis of action potentials in the canine ventricular septum: no phenotypic expression of M cells.

Journal: Cardiovascular research 20070401

Title: Elimination of beta-blockers in sewage treatment plants.

Journal: Water research 20070401

Title: Exercise capacity in atrial fibrillation: a substudy of the Sotalol-Amiodarone Atrial Fibrillation Efficacy Trial (SAFE-T).

Journal: American heart journal 20070401

Title: Antiarrhythmic drugs: present and future.

Journal: The Journal of the Association of Physicians of India 20070401

Title: Simultaneous determination of ten antiarrhythic drugs and a metabolite in human plasma by liquid chromatography--tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301

Title: Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function.

Journal: Journal of cardiovascular pharmacology and therapeutics 20070301

Title: Methodological validation of an existing telemetry system for QT evaluation in conscious guinea pigs.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: The effect of high extracellular potassium on IKr inhibition by anti-arrhythmic agents.

Journal: Cardiology 20070101

Title: Prophylactic therapy to prevent atrial arrhythmia after cardiac surgery.

Journal: Current opinion in cardiology 20070101

Title: Drug-induced QT prolongation: consequences and current dilemma.

Journal: British journal of hospital medicine (London, England : 2005) 20070101

Title: The effects of plasma proteins on delayed repolarization in vitro with cisapride, risperidone, and D, L-sotalol.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: [Comparative study of the electrophysiological properties of class iii medicinals (cardiocyclide, nibentan, sotalol) and evaluation of their efficacy in atrial fibrillation produced by auricular and vagal stimulation].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20070101

Title: [Effect of bisoprolol and sotalol on clinical status of patients with proximal form of atrial fibrillation and chronic heart failure].

Journal: Kardiologiia 20070101

Title: Management of infants with idiopathic dilatation of the right atrium and atrial tachycardia.

Journal: Pediatric cardiology 20070101

Title: Suitability of commonly used excipients for electrophysiological in-vitro safety pharmacology assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: Action potential experiments complete hERG assay and QT-interval measurements in cardiac preclinical studies.

Journal: Journal of pharmacological and toxicological methods 20070101

Title: The clinical noncompliance of oral sotalol/magnesium for prophylactic treatment of atrial fibrillation after coronary artery bypass grafting.

Journal: Journal of cardiac surgery 20070101

Title: The changing face of postoperative atrial fibrillation prevention: a review of current medical therapy.

Journal: Cardiology in review 20070101

Title: [Arrhythmias in pregnancy. How and when to treat?].

Journal: Archivos de cardiologia de Mexico 20070101

Title: [Influence of perindopril, rosuvastatin, or omega-3 polyunsaturated fatty acids on efficacy of antirecurrence therapy with sotalol in patients with persistent atrial fibrillation].

Journal: Kardiologiia 20070101

Title: A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study.

Journal: Journal of the American College of Cardiology 20061205

Title: Guidelines on the prevention and management of de novo atrial fibrillation after cardiac and thoracic surgery.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20061201

Title: Comparison of four rate-correction algorithms for the ventricular repolarization period in assessing net effects of IKr blockers in dogs.

Journal: Journal of pharmacological sciences 20061201

Title: Comparison of a standard versus accelerated dosing regimen for D,L-sotalol for the treatment of atrial and ventricular dysrhythmias.

Journal: Pacing and clinical electrophysiology : PACE 20061101

Title: Cytochrome P450 (CYP) inhibition screening: comparison of three tests.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20061001

Title: Determinants of sudden cardiac death in patients with persistent atrial fibrillation in the rate control versus electrical cardioversion (RACE) study.

Journal: The American journal of cardiology 20061001

Title: QT-RR relationships and suitable QT correction formulas for halothane-anesthetized dogs.

Journal: The Journal of toxicological sciences 20061001

Title: Attenuation of the negative inotropic effects of metoprolol at short cycle lengths in humans: comparison with sotalol and verapamil.

Journal: Journal of the American College of Cardiology 20060919

Title: Azimilide vs. placebo and sotalol for persistent atrial fibrillation: the A-COMET-II (Azimilide-CardiOversion MaintEnance Trial-II) trial.

Journal: European heart journal 20060901

Title: Quality of life and exercise performance in patients in sinus rhythm versus persistent atrial fibrillation: a Veterans Affairs Cooperative Studies Program Substudy.

Journal: Journal of the American College of Cardiology 20060815

Title: Atrial fibrillation post-cardiac surgery: changing perspectives.

Journal: Current medical research and opinion 20060801

Title: Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.

Journal: Circulation 20060711

Title: Development an ion-pair liquid chromatographic method for determination of sotalol in plasma using a monolithic column.

Journal: Journal of pharmaceutical and biomedical analysis 20060616

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Comparison of efficacy of sotalol and nifekalant for ventricular tachyarrhythmias.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20060501

Title: Transdermal delivery of beta-blockers.

Journal: Expert opinion on drug delivery 20060501

Title: Mechanisms underlying the QT interval-prolonging effects of sevoflurane and its interactions with other QT-prolonging drugs.

Journal: Anesthesiology 20060501

Title: Sotalol in the treatment of fetal tachyarrhythmia.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20060501

Title: A randomized trial of prophylactic antiarrhythmic agents (amiodarone and sotalol) in patients with atrial fibrillation for whom direct current cardioversion is planned.

Journal: American heart journal 20060401

Title: Characterization of the halothane-anesthetized guinea-pig heart as a model to detect the K+ channel blocker-induced QT-interval prolongation.

Journal: Biological & pharmaceutical bulletin 20060401

Title: A micromethod for the quantification of atenolol in plasma using high-performance liquid chromatography with fluorescence detection: therapeutic drug monitoring of two patients with severe coronary insufficiency before cardiac surgery.

Journal: Therapeutic drug monitoring 20060401

Title: An evaluation of the impact of oral magnesium lactate on the corrected QT interval of patients receiving sotalol or dofetilide to prevent atrial or ventricular tachyarrhythmia recurrence.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20060401

Title: Combined use of 1C and III agents for highly symptomatic, refractory atrial fibrillation.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20060401

Title: Epinephrine administration increases neural impulses propagated along the vagus nerve: Role of peripheral beta-adrenergic receptors.

Journal: Neurobiology of learning and memory 20060301

Title: Intra-adrenal interactions in fish: catecholamine stimulated cortisol release in sea bass (Dicentrarchus labrax L.).

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20060301

Title: Inadvertent toxic drug reaction in the management of atrial fibrillation.

Journal: Journal of the Royal Society of Medicine 20060301

Title: Tachycardia-induced elevations in cardiac troponin in the absence of coronary artery disease.

Journal: Hawaii medical journal 20060301

Title: Fetal atrial flutter: a case report and experience of sotalol treatment.

Journal: Taiwanese journal of obstetrics & gynecology 20060301

Title: [Conversion to sinus rhythm].

Journal: Praxis 20060215

Title: [Present status in and prospects for anti-arrhythmic drug therapy: How to use type III anti-arrhythmic agents].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060210

Title: Rate of conversion and recurrence after sotalol treatment in patients with direct current-refractory atrial fibrillation.

Journal: Clinical cardiology 20060201

Title: [Conversion in sinus rhythm].

Journal: Praxis 20060201

Title: Amiodarone versus Sotalol and Propafenone for prevention of immediate recurrence of atrial fibrillation after internal cardioversion: importance of P wave analysis.

Journal: International journal of cardiology 20060113

Title: Comparison of beta-blockers, amiodarone plus beta-blockers, or sotalol for prevention of shocks from implantable cardioverter defibrillators: the OPTIC Study: a randomized trial.

Journal: JAMA 20060111

Title: [Effects of amiodarone versus sotalol in treatment of atrial fibrillation: a random controlled clinical study].

Journal: Zhonghua yi xue za zhi 20060110

Title: [Implantable cardioverter defibrillator does not eliminate need for antiarrhythmic drugs in secondary prevention of life threatening ventricular arrhythmias. Results of OPTIC trial].

Journal: Kardiologiia 20060101

Title: Does prophylactic sotalol and magnesium decrease the incidence of atrial fibrillation following coronary artery bypass surgery: a propensity-matched analysis.

Journal: Journal of cardiothoracic surgery 20060101

Title: Safety pharmacology assessment of drug-induced QT-prolongation in dogs with reduced repolarization reserve.

Journal: Journal of pharmacological and toxicological methods 20060101

Title: Sustained torsade de pointes occurring early during oral sotalol therapy for atrial fibrillation recurrence prophylaxis in a patient without heart disease.

Journal: International journal of cardiology 20051207

Title: [Atrial flutter and fibrillation].

Journal: Praxis 20051109

Title: Sotalol and amiodarone versus digoxin for conversion of recent onset atrial fibrillation.

Journal: American heart journal 20051101

Title: Development of a safe and effective pediatric dosing regimen for sotalol based on population pharmacokinetics and pharmacodynamics in children with supraventricular tachycardia.

Journal: Journal of the American College of Cardiology 20051004

Title: Reduction of repolarization reserve by halothane anaesthesia sensitizes the guinea-pig heart for drug-induced QT interval prolongation.

Journal: British journal of pharmacology 20051001

Title: Severe poisoning with sotalol and verapamil. Recovery after 4 h of normothermic CPR followed by extra corporeal heart lung assist.

Journal: Acta anaesthesiologica Scandinavica 20051001

Title: Halothane sensitizes the guinea-pig heart to pharmacological IKr blockade: comparison with urethane anesthesia.

Journal: Journal of pharmacological sciences 20051001

Title: The electrocardiogram of human embryonic stem cell-derived cardiomyocytes.

Journal: Journal of electrocardiology 20051001

Title: Drug therapy in Brugada syndrome.

Journal: Current drug targets. Cardiovascular & haematological disorders 20051001

Title: Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

Journal: Circulation 20050906

Title: Randomized double-blind trial of sotalol versus lignocaine in out-of-hospital refractory cardiac arrest due to ventricular tachyarrhythmia.

Journal: Internal medicine journal 20050901

Title: Ablation of atrial fibrillation using microwave energy--early experience.

Journal: Asian cardiovascular & thoracic annals 20050901

Title: Potential proarrhythmic effect of biventricular pacing: fact or myth?

Journal: Heart rhythm 20050901

Title: Proarrhythmias and antiarrhythmias: two sides of the same coin.

Journal: Heart rhythm 20050901

Title: Case records of the Massachusetts General Hospital. Case 26-2005. A 48-year-old man with sudden loss of consciousness while jogging.

Journal: The New England journal of medicine 20050825

Title: Amiodarone versus sotalol for atrial fibrillation.

Journal: The New England journal of medicine 20050811

Title: Amiodarone versus sotalol for atrial fibrillation.

Journal: The New England journal of medicine 20050811

Title: Amiodarone versus sotalol for atrial fibrillation.

Journal: The New England journal of medicine 20050811

Title: Assessment of the effect of a single oral dose of telithromycin on sotalol-induced qt interval prolongation in healthy women.

Journal: British journal of clinical pharmacology 20050801

Title: [PAFAC Study. Secondary prevention of atrial fibrillation after cardioversion].

Journal: Der Internist 20050701

Title: Consequences of atrial electrical remodeling for the anti-arrhythmic action of class IC and class III drugs.

Journal: Cardiovascular research 20050701

Title: Digital 12-lead Holter in the assessment of drug effects on cardiac repolarization.

Journal: Journal of electrocardiology 20050701

Title: Effect of concomitant antiarrhythmic therapy on survival in patients with implantable cardioverter defibrillators.

Journal: Pacing and clinical electrophysiology : PACE 20050701

Title: Amiodarone versus sotalol for atrial fibrillation.

Journal: The New England journal of medicine 20050505

Title: Liquid-phase microextraction based on carrier mediated transport combined with liquid chromatography-mass spectrometry. New concept for the determination of polar drugs in a single drop of human plasma.

Journal: Journal of chromatography. A 20050422

Title: Differential effects of human ether-a-go-go-related gene (HERG) blocking agents on QT duration variability in conscious dogs.

Journal: European journal of pharmacology 20050404

Title: The effects of sotalol on ventricular repolarization during exercise.

Journal: Journal of Zhejiang University. Science. B 20050401

Title: Electrophysiologic study-guided therapy with sotalol for life-threatening ventricular tachyarrhythmias.

Journal: Pacing and clinical electrophysiology : PACE 20050401

Title: Hybrid therapy with right atrial catheter ablation and previously ineffective antiarrhythmic drugs for the management of atrial fibrillation.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20050401

Title: [Calmodulin antagonist inhibits torsade de pointes induced by d-sotalol in an isolated rabbit heart model].

Journal: Zhonghua xin xue guan bing za zhi 20050401

Title: Electrophysiological effects of flecainide and sotalol in the human atrium during persistent atrial fibrillation.

Journal: Basic research in cardiology 20050301

Title: Pharmacologic strategies for prevention of atrial fibrillation after open heart surgery.

Journal: The Annals of thoracic surgery 20050201

Title: Tetraethylammonium exacerbates ischemic neuronal injury in rat cerebrocortical slice cultures.

Journal: European journal of pharmacology 20050131

Title: Additive effects of ziprasidone and D,L-sotalol on the action potential in rabbit Purkinje fibres and on the hERG potassium current.

Journal: Journal of pharmacological and toxicological methods 20050101

Title: [Possibility of differentiated treatment of ventricular heart rate disturbances based on mechanism of their development].

Journal: Kardiologiia 20050101

Title: Successful management of supraventricular tachycardia in a fetus using fetal magnetocardiography.

Journal: Fetal diagnosis and therapy 20050101

Title: Development of an intravenous microdialysis method for pharmacokinetic investigations in humans.

Journal: Journal of pharmacological and toxicological methods 20050101

Title: [A comparative study of the effects of antiarrhythmic class III drugs cardiocyclide and sotalol on the atrioventricular fibrillation caused by vagus nerve excitation in narcotized dogs].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20050101

Title: QT PRODACT: inter- and intra-facility variability of the action potential assay using isolated guinea-pig papillary muscles.

Journal: Journal of pharmacological sciences 20050101

Title: QT PRODACT: usability of miniature pigs in safety pharmacology studies: assessment for drug-induced QT interval prolongation.

Journal: Journal of pharmacological sciences 20050101

Title: QT PRODACT: inter-facility variability in electrocardiographic and hemodynamic parameters in conscious dogs and monkeys.

Journal: Journal of pharmacological sciences 20050101

Title: Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation.

Journal: The American journal of cardiology 20041215

Title: Advantages and pitfalls of combining device-based and pharmacologic therapies for the treatment of ventricular arrhythmias: observations from a tertiary referral center.

Journal: Pacing and clinical electrophysiology : PACE 20041201

Title: A benefit-risk assessment of class III antiarrhythmic agents.

Journal: Expert opinion on drug safety 20041101

Title: Sotalol-induced coronary spasm in a patient with dilated cardiomyopathy associated with sustained ventricular tachycardia.

Journal: Internal medicine (Tokyo, Japan) 20041101

Title: Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs.

Journal: Circulation 20041019

Title: Amiodarone versus sotalol for the treatment of atrial fibrillation after open heart surgery: the Reduction in Postoperative Cardiovascular Arrhythmic Events (REDUCE) trial.

Journal: American heart journal 20041001

Title: Fetal supraventricular tachycardia diagnosed and treated at twenty-four weeks of gestation and after birth: a case report.

Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20041001

Title: Limitations to antiarrhythmic drug use in patients with atrial fibrillation.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20040928

Title: Chemoenzymatic synthesis of (S) and (R)-propranolol and sotalol employing one-pot lipase resolution protocol.

Journal: Bioorganic & medicinal chemistry letters 20040906

Title: Comparison of the in vitro electrophysiologic and proarrhythmic effects of amiodarone and sotalol in a rabbit model of acute atrioventricular block.

Journal: Journal of cardiovascular pharmacology 20040901

Title: Prevention of atrial fibrillation after cardioversion: results of the PAFAC trial.

Journal: European heart journal 20040801

Title: Suppression of paroxysmal atrial tachyarrhythmias--results of the SOPAT trial.

Journal: European heart journal 20040801

Title: Sotalol reverses remodeled action potential in patients with chronic atrial fibrillation but does not prevent arrhythmia recurrence.

Journal: Journal of cardiovascular electrophysiology 20040801

Title: Is atrial remodeling a viable target for prevention of atrial fibrillation recurrence?

Journal: Journal of cardiovascular electrophysiology 20040801

Title: [Perspectives and limitations in the treatment of vagus-induced atrial fibrillation. Insights from cellular pharmacology].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20040715

Title: Intrapericardial delivery enhances cardiac effects of sotalol and atenolol.

Journal: Journal of cardiovascular pharmacology 20040701

Title: Biopharmaceutical characterization of sotalol-containing oral immediate release drug products.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040701

Title: Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20040701

Title: Magnesium in addition to sotalol does not influence the incidence of postoperative atrial tachyarrhythmias after coronary artery bypass surgery.

Journal: Journal of cardiothoracic and vascular anesthesia 20040601

Title: Effectiveness of sotalol treatment in symptomatic Brugada syndrome.

Journal: The American journal of cardiology 20040515

Title: [Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].

Journal: Orvosi hetilap 20040509

Title: Long-term follow-up of implantable cardioverter defibrillator therapy for hypertrophic cardiomyopathy.

Journal: The American journal of cardiology 20040501

Title: Short QT syndrome: pharmacological treatment.

Journal: Journal of the American College of Cardiology 20040421

Title: A comparison between oral antiarrhythmic drugs in the prevention of atrial fibrillation after cardiac surgery: the pilot study of prevention of postoperative atrial fibrillation (SPPAF), a randomized, placebo-controlled trial.

Journal: American heart journal 20040401

Title: Experimental study on the mechanism of sex difference in the risk of torsade de pointes.

Journal: Chinese medical journal 20040401

Title: Atrial fibrillation: rate control often better than rhythm control.

Journal: Prescrire international 20040401

Title: Preoperative use of sotalol versus atenolol for atrial fibrillation after cardiac surgery.

Journal: The Annals of thoracic surgery 20040301

Title: Role of dipolar and nondipolar components of the T wave in determining the T wave residuum in an isolated rabbit heart model.

Journal: Journal of cardiovascular electrophysiology 20040301

Title: Antiarrhythmic drug therapy of atrial fibrillation.

Journal: Cardiology clinics 20040201

Title: Long-term efficacy of atenolol for atrioventricular reciprocating tachycardia in children less than 5 years old.

Journal: Pediatric cardiology 20040101

Title: Oral class III antiarrhythmics: what is new?

Journal: Current opinion in cardiology 20040101

Title: Rapid loading of sotalol or amiodarone for management of recent onset symptomatic atrial fibrillation: a randomized, digoxin-controlled trial.

Journal: American heart journal 20040101

Title: Establishment of an enzyme-linked immunosorbent assay for measurement of sotalol.

Journal: Biological & pharmaceutical bulletin 20040101

Title: Electrocardiographic identification of drug-induced QT prolongation: assessment by different recording and measurement methods.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20040101

Title: Novel antiarrhythmic compounds with combined class IB and class III mode of action.

Journal: Current medicinal chemistry 20040101

Title: [Correction of rate and structure of ventricular rhythm in permanent atrial fibrillation: a novel pathogenetic approach].

Journal: Kardiologiia 20040101

Title: Sotalol-induced depression.

Journal: The Annals of pharmacotherapy 20040101

Title: Seventy-four defibrillations for sotalol-induced torsades de pointes.

Journal: Indian heart journal 20040101

Title: QT and RR intervals in conscious and anesthetized guinea pigs with highly varying RR intervals and given QTc-lengthening test articles.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031201

Title: Atrial stunning: basics and clinical considerations.

Journal: International journal of cardiology 20031201

Title: Initiation and monitoring of class III antiarrhythmic agents.

Journal: Journal of cardiovascular electrophysiology 20031201

Title: Evaluation of the dofetilide risk-management program.

Journal: American heart journal 20031101

Title: Beta receptor blockade potentiates the antiarrhythmic actions of d-sotalol on reentrant ventricular tachycardia in a canine model of myocardial infarction.

Journal: Journal of cardiovascular electrophysiology 20031101

Title: Torsades de pointes following cardioversion: case history and literature review.

Journal: Australian critical care : official journal of the Confederation of Australian Critical Care Nurses 20031101

Title: Enantioselective liquid chromatographic-electrospray mass spectrometric assay of beta-adrenergic blockers: application to a pharmacokinetic study of sotalol in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031025

Title: Arrhythmias in the intensive care patient.

Journal: Current opinion in critical care 20031001

Title: New antiarrhythmic agents for atrial fibrillation and atrial flutter: United States drug market response as an indicator of acceptance.

Journal: Pharmacotherapy 20031001

Title: [Sotalol in treatment of pediatric severe (refractory) cardiac arrhythmias].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20031001

Title: Clinical predictors and time course of arrhythmia recurrence in patients with early reinitiation of atrial fibrillation after successful internal cardioversion.

Journal: Pacing and clinical electrophysiology : PACE 20030901

Title: Pure class III agents for prevention of sudden cardiac death.

Journal: Journal of cardiovascular electrophysiology 20030901

Title: Iontophoretic in vivo transdermal delivery of beta-blockers in hairless rats and reduced skin irritation by liposomal formulation.

Journal: Pharmaceutical research 20030901

Title: Cost evaluation of rhythm control methods for atrial fibrillation: evidence from CTAF.

Journal: Cardiac electrophysiology review 20030901

Title: Quality of life variables in the selection of rate versus rhythm control in patients with atrial fibrillation: observations from the Canadian Trial of Atrial Fibrillation.

Journal: Cardiac electrophysiology review 20030901

Title: Facilitating electrical cardioversion of persistant atrial fibrillation by antiarrhythmic drugs: update on clinical trial results.

Journal: Cardiac electrophysiology review 20030901

Title: Treatment of fetal tachycardia with sotalol: transplacental pharmacokinetics and pharmacodynamics.

Journal: Journal of the American College of Cardiology 20030820

Title: Comparison of sotalol versus amiodarone in maintaining stability of sinus rhythm in patients with atrial fibrillation (Sotalol-Amiodarone Fibrillation Efficacy Trial [Safe-T]).

Journal: The American journal of cardiology 20030815

Title: Fully automated LC method for the determination of sotalol in human plasma using restricted access material with cation exchange properties for sample clean-up.

Journal: Journal of pharmaceutical and biomedical analysis 20030808

Title: A review of the class III antiarrhythmic agents and their uses and implications for patient management.

Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20030801

Title: Maintenance of sinus rhythm in patients with atrial fibrillation: an AFFIRM substudy of the first antiarrhythmic drug.

Journal: Journal of the American College of Cardiology 20030702

Title: Impact of left atrial size reduction on chronic atrial fibrillation in mitral valve surgery.

Journal: The Journal of heart valve disease 20030701

Title: [Dramatic symptoms of pheochromocytoma in old woman during antiarrhythmic therapy with sotalol: case report].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030701

Title: Atrial fibrillation after cardiac surgery: evidence on prophylactic interventions.

Journal: Expert review of cardiovascular therapy 20030701

Title: [Results of prenatal management of fetuses with supraventricular tachycardia. A series of 66 cases].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20030601

Title: Clinical usefulness of electrophysiologic testing in patients with ventricular tachycardia and chronic chagasic cardiomyopathy treated with amiodarone or sotalol.

Journal: Journal of cardiovascular electrophysiology 20030601

Title: Do we need a randomized trial of defibrillator therapy in every subset of patients with increased risk of sudden death?

Journal: Journal of cardiovascular electrophysiology 20030601

Title: Combination therapy for prevention of atrial fibrillation after coronary artery bypass surgery: a randomized trial of sotalol and magnesium.

Journal: Cardiac electrophysiology review 20030601

Title: Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results.

Journal: Cardiac electrophysiology review 20030601

Title: Atrial fibrillation after cardiac surgery: update on the evidence on the available prophylactic interventions.

Journal: Cardiac electrophysiology review 20030601

Title: Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation: the Strategies of Treatment of Atrial Fibrillation (STAF) study.

Journal: Journal of the American College of Cardiology 20030521

Title: Meta-analysis of antiarrhythmic therapy in the prevention of postoperative atrial fibrillation and the effect on hospital length of stay, costs, cerebrovascular accidents, and mortality in patients undergoing cardiac surgery.

Journal: The American journal of cardiology 20030501

Title: Electrical heterogeneity and arrhythmogenesis: importance of conduction velocity dispersion.

Journal: Journal of cardiovascular pharmacology 20030501

Title: A case series of sotalol-induced torsade de pointes in patients with atrial fibrillation--a tale with a twist.

Journal: Annals of the Academy of Medicine, Singapore 20030501

Title: Sotalol testing unmasks altered repolarization in patients with suspected acquired long-QT-syndrome--a case-control pilot study using i.v. sotalol.

Journal: European heart journal 20030401

Title: Effect of sotalol and acute ventricular dilatation on action potential duration and dispersion of repolarization after defibrillation shocks.

Journal: Journal of cardiovascular pharmacology 20030401

Title: Stability of sotalol in two liquid formulations at two temperatures.

Journal: The Annals of pharmacotherapy 20030401

Title: Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.

Journal: The American journal of cardiology 20030320

Title: Risk of proarrhythmia with class III antiarrhythmic agents: sex-based differences and other issues.

Journal: The American journal of cardiology 20030320

Title: Excitable gap composition in the presence of antiarrhythmic drugs in common human atrial flutter.

Journal: The Canadian journal of cardiology 20030315

Title: Prolonged action potential durations, increased dispersion of repolarization, and polymorphic ventricular tachycardia in a mouse model of proarrhythmia.

Journal: Basic research in cardiology 20030201

Title: Identification and management of ventricular tachycardia.

Journal: Journal of the Indian Medical Association 20030201

Title: Findings suggest revised atrial fibrillation approach.

Journal: Report on medical guidelines & outcomes research 20030110

Title: [Comparative study of electrophysiological mechanisms of anti-arrhythmia III class agents, cardiocyclide, nibentan, and sotalol during experimental myocardial infarction and sympathetic stimulation].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20030101

Title: Potentially significant drug interactions of class III antiarrhythmic drugs.

Journal: Drug safety 20030101

Title: Intracardiac low-energy versus transthoracic high-energy direct-current cardioversion of atrial fibrillation: a randomised comparison.

Journal: Cardiology 20030101

Title: Long-term follow-up of sudden cardiac arrest survivors and electrophysiologically guided antiarrhythmic therapy.

Journal: Cardiology 20030101

Title: [Anti-arrhythmic therapy: diagnostic possibilities of signal-averaged electrocardiography and heart rate variability].

Journal: Kardiologiia 20030101

Title: [Effect of drug therapy on frequency of adequate discharges of implanted cardioverter defibrillator].

Journal: Kardiologiia 20030101

Title: Identification of sotalol-induced changes in repolarization with T wave area-based repolarization duration parameters.

Journal: Journal of electrocardiology 20030101

Title: [Chronic heart failure and atrial fibrilation: aspects of management].

Journal: Kardiologiia 20030101

Title: Electrophysiologic actions of dl-sotalol in patients with persistent atrial fibrillation.

Journal: Journal of the American College of Cardiology 20021218

Title: Electrophysiological and antiarrhythmic effects of the novel I(Kur) channel blockers, S9947 and S20951, on left vs. right pig atrium in vivo in comparison with the I(Kr) blockers dofetilide, azimilide, d,l-sotalol and ibutilide.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20021101

Title: [Recent findings on the dromotropic actions of the class III antiarrhythmic agents].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101

Title: Efficacy of metoprolol and sotalol in the prevention of recurrences of sustained ventricular tachyarrhythmias in patients with an implantable cardioverter defibrillator.

Journal: Pacing and clinical electrophysiology : PACE 20021101

Title: New insights into the mechanisms and management of atrial fibrillation.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20021029

Title: Management and outcome of patients with atrial fibrillation during acute myocardial infarction: the GUSTO-III experience. Global use of strategies to open occluded coronary arteries.

Journal: Heart (British Cardiac Society) 20021001

Title: A potassium ion channel is involved in cytokine production by activated human macrophages.

Journal: Clinical and experimental immunology 20021001

Title: Rate-correction technique for QT interval in long-term telemetry ECG recording in beagle dogs.

Journal: Experimental animals 20021001

Title: Overview of randomized trials of antiarrhythmic drugs and devices for the prevention of sudden cardiac death.

Journal: American heart journal 20020901

Title: Combination of sotalol and magnesium prevents atrial fibrillation after coronary artery bypass grafting.

Journal: The Annals of thoracic surgery 20020901

Title: Comparison of the effects of four antiarrhythmic treatments for familial ventricular arrhythmias in Boxers.

Journal: Journal of the American Veterinary Medical Association 20020815

Title: Enantioselective determination of (R)- and (S)-sotalol in human plasma by on-line coupling of a restricted-access material precolumn to a cellobiohydrolase I-based chiral stationary phase.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020805

Title: Implantable cardiac defibrillators.

Journal: The New England journal of medicine 20020801

Title: Buccal transport of flecainide and sotalol: effect of a bile salt and ionization state.

Journal: International journal of pharmaceutics 20020708

Title: Interventions on prevention of postoperative atrial fibrillation in patients undergoing heart surgery: a meta-analysis.

Journal: Circulation 20020702

Title: Amiodarone: pearl or peril?

Journal: European heart journal 20020701

Title: Amiodarone reduces procedures and costs related to atrial fibrillation in a controlled clinical trial.

Journal: European heart journal 20020701

Title: Transient atrial mechanical dysfunction (stunning) after cardioversion of atrial fibrillation and flutter.

Journal: American heart journal 20020701

Title: Centrally applied nitric oxide donor elevates plasma corticosterone by activation of the hypothalamic noradrenergic neurons in rats.

Journal: Brain research 20020607

Title: An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation.

Journal: European heart journal 20020601

Title: Quality of life improves with treatment in the Canadian Trial of Atrial Fibrillation.

Journal: American heart journal 20020601

Title: A randomised cross-over study on the haemodynamic effects of oral dofetilide compared with oral sotalol in patients with ischaemic heart disease and sustained ventricular tachycardia.

Journal: European journal of clinical pharmacology 20020601

Title: Preconditioning attenuates the shortening of recovery during coronary occlusion in isolated rabbit hearts with D-sotalol-induced long QT intervals.

Journal: Journal of cardiovascular pharmacology 20020501

Title: Atrial fibrillation recurrence after internal cardioversion: prognostic importance of electrophysiological parameters.

Journal: Heart (British Cardiac Society) 20020501

Title: Hypertrophic cardiomyopathy with massive hypertrophy, amiodarone treatment and high defibrillation threshold at cardioverter-defibrillator implant.

Journal: International journal of cardiology 20020501

Title: Suppression of atrial fibrillation by multisite and septal pacing in a novel experimental model.

Journal: Cardiovascular research 20020501

Title: Drug-induced ventricular tachyarrhythmia in isolated rabbit hearts with atrioventricular block.

Journal: Pharmacology & toxicology 20020501

Title: Maintainance of sinus rhythm after electrical cardioversion of persistent atrial fibrillation.

Journal: European heart journal 20020401

Title: Amiodarone vs. sotalol as prophylaxis against atrial fibrillation/flutter after heart surgery: a meta-analysis.

Journal: Chest 20020401

Title: Relationship between the U wave on electrocardiogram and the midmyocardium of the left ventricular wall.

Journal: Chinese medical journal 20020401

Title: Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome.

Journal: Circulation 20020312

Title: Flecainide and sotalol: a new combination therapy for refractory supraventricular tachycardia in children <1 year of age.

Journal: Journal of the American College of Cardiology 20020206

Title: Proarrhythmic effects of intravenous quinidine, amiodarone, D-sotalol, and almokalant in the anesthetized rabbit model of torsade de pointes.

Journal: Journal of cardiovascular pharmacology 20020201

Title: New antiarrhythmic drugs for the treatment of atrial fibrillation.

Journal: Pacing and clinical electrophysiology : PACE 20020201

Title: Electrophysiologic characterization of the antipsychotic drug sertindole in a rabbit heart model of torsade de pointes: low torsadogenic potential despite QT prolongation.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Drug treatment of fetal tachycardias.

Journal: Paediatric drugs 20020101

Title: Prenatal ultrasound may predict fetal response to therapy in non-hydropic fetuses with supraventricular tachycardia.

Journal: Fetal diagnosis and therapy 20020101

Title: The cellular electrophysiologic effect of a new amiodarone like antiarrhythmic drug GYKI 16638 in undiseased human ventricular muscle: comparison with sotalol and mexiletine.

Journal: Current medicinal chemistry 20020101

Title: Combination IK1 and IKr channel blockade: no additive lowering of the defibrillation threshold.

Journal: Canadian journal of physiology and pharmacology 20020101

Title: Kinetic disposition of (+)-S- and (-)-R-sotalol enantiomers in cardiac patients with tachyarrhythmias using an improved HPLC-fluorescence stereoselective method.

Journal: Bollettino chimico farmaceutico 20020101

Title: Fractal dynamics of heart beat interval fluctuations in corticotropin-releasing factor receptor subtype 2 deficient mice.

Journal: Integrative physiological and behavioral science : the official journal of the Pavlovian Society 20020101

Title: A method for QT correction based on beat-to-beat analysis of the QT/RR interval relationship in conscious telemetred beagle dogs.

Journal: Journal of pharmacological and toxicological methods 20020101

Title: [Atrial fibrillation successfully converted. A new standard in the prevention of recurrence?].

Journal: MMW Fortschritte der Medizin 20011213

Title: (+/-)-sotalol alters neither the shape of the T wave downslope nor the U wave; a magnetocardiographic study.

Journal: British journal of clinical pharmacology 20011201

Title: Sotalol in treatment of pediatric cardiac arrhythmias.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20011201

Title: Effect of metoprolol and d,l-sotalol on microvolt-level T-wave alternans. Results of a prospective, double-blind, randomized study.

Journal: Journal of the American College of Cardiology 20011201

Title: A review of class III antiarrhythmic agents for atrial fibrillation: maintenance of normal sinus rhythm.

Journal: Pharmacotherapy 20011201

Title: [Chronic hepatitis ascribed to the use of sotalol].

Journal: Nederlands tijdschrift voor geneeskunde 20011201

Title: Cellular basis for complex T waves and arrhythmic activity following combined I(Kr) and I(Ks) block.

Journal: Journal of cardiovascular electrophysiology 20011201

Title: Amplified effects of d,l-sotalol in canine dilated cardiomyopathy.

Journal: Pacing and clinical electrophysiology : PACE 20011201

Title: A multicentre, double-blind randomized crossover comparative study on the efficacy and safety of dofetilide vs sotalol in patients with inducible sustained ventricular tachycardia and ischaemic heart disease.

Journal: European heart journal 20011201

Title: Population pharmacokinetics and pharmacodynamics of sotalol in pediatric patients with supraventricular or ventricular tachyarrhythmia.

Journal: Journal of pharmacokinetics and pharmacodynamics 20011201

Title: Scavenger effect of experimental and clinically used cardiovascular drugs.

Journal: Journal of cardiovascular pharmacology 20011101

Title: Influence of age, the autonomic nervous system and anxiety on QT-interval variability.

Journal: Clinical science (London, England : 1979) 20011001

Title: Effect of Sotalol in the prevention of atrial fibrillation following coronary artery bypass grafting.

Journal: The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi 20011001

Title: Is it rational, reasonable or excessive, and consistently applied? One view of the increasing FDA emphasis on safety first for the release and use of antiarrhythmic drugs for supraventricular arrhythmias.

Journal: Journal of cardiovascular pharmacology and therapeutics 20011001

Title: Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation.

Journal: The American journal of cardiology 20010915

Title: Multi-morphology wide QRS tachycardias in a patient without structural heart disease: an unusual presentation of ventricular tachycardia.

Journal: Japanese heart journal 20010901

Title: Sotalol: a fool's deal?

Journal: European heart journal 20010801

Title: Maintenance of sinus rhythm after electrical cardioversion of persistent atrial fibrillation; sotalol vs bisoprolol.

Journal: European heart journal 20010801

Title: Effects of oral sotalol administration before electrical cardioversion of persistent atrial fibrillation.

Journal: European heart journal 20010801

Title: Correlation between the effective refractory period and activation-recovery interval calculated from the intracardiac unipolar electrogram of humans with and without dl-sotalol treatment.

Journal: Japanese circulation journal 20010801

Title: Oral amiodarone and atrial fibrillation.

Journal: Lancet (London, England) 20010714

Title: d,l-sotalol enhances baroreflex sensitivity in conscious rats surviving acute myocardial infarction.

Journal: Pharmacological research 20010701

Title: Shortening the second phase duration of biphasic shocks: effects of class III antiarrhythmic drugs on defibrillation efficacy in humans.

Journal: Journal of cardiovascular electrophysiology 20010701

Title: [Protocols for the treatment of supraventricular tachycardias in the fetus].

Journal: Nederlands tijdschrift voor geneeskunde 20010623

Title: Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome : direct evidence from intracellular recordings in the intact left ventricular wall.

Journal: Circulation 20010612

Title: Comparison of class III antiarrhythmic drugs versus digoxin for the reversion of new-onset atrial fibrillation.

Journal: Annals of emergency medicine 20010601

Title: The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis.

Journal: Journal of cardiovascular pharmacology 20010501

Title: Drug-disease interactions: reduced beta-adrenergic and potassium channel antagonist activities of sotalol in the presence of acute and chronic inflammatory conditions in the rat.

Journal: British journal of pharmacology 20010501

Title: Termination of automatic atrial tachycardia in an infant by adequate sotalol dosing. Indication of clinically relevant age-dependent pharmacokinetics of sotalol.

Journal: European journal of clinical pharmacology 20010501

Title: Small blood volumes from children for quantitative sotalol determination using high-performance liquid chromatography.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010405

Title: Control of vascular tone in notothenioid fishes is determined by phylogeny, not environmental temperature.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010401

Title: The class III antiarrhythmic drugs dofetilide and sotalol prevent AF induction by atrial premature complexes at doses that fail to terminate AF.

Journal: Cardiovascular research 20010401

Title: CIBIS, MERIT-HF, and COPERNICUS trial outcomes: do they complete the chapter on beta-adrenergic blockers as antiarrhythmic and antifibrillatory drugs?

Journal: Journal of cardiovascular pharmacology and therapeutics 20010401

Title: Pharmacokinetics and pharmacodynamics of sotalol in a pediatric population with supraventricular and ventricular tachyarrhythmia.

Journal: Clinical pharmacology and therapeutics 20010301

Title: Development and validation of an automated method for the liquid chromatographic determination of sotalol in plasma using dialysis and trace enrichment on a cation-exchange pre-column as on-line sample preparation.

Journal: Journal of pharmaceutical and biomedical analysis 20010301

Title: Does prophylaxis against atrial fibrillation after cardiac surgery reduce length of stay or hospital costs?

Journal: Pharmacotherapy 20010301

Title: Global distribution of atrial ectopic foci triggering recurrence of atrial tachyarrhythmia after electrical cardioversion of long-standing atrial fibrillation: a bi-atrial basket mapping study.

Journal: Journal of the American College of Cardiology 20010301

Title: Which beta-blocker?

Journal: The Medical letter on drugs and therapeutics 20010205

Title: Meta-analysis of the Risk of Torsades de Pointes in patients treated with intravenous racemic sotalol.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20010201

Title: Effects of acute global low-flow ischemia on triggered arrhythmias in d-sotalol-induced long Q-T intervals in perfused rabbit hearts.

Journal: Journal of cardiovascular pharmacology 20010201

Title: 'Stable' ventricular tachycardia is not a benign rhythm : insights from the antiarrhythmics versus implantable defibrillators (AVID) registry.

Journal: Circulation 20010116

Title: Single-dose pharmacokinetics of sotalol in a pediatric population with supraventricular and/or ventricular tachyarrhythmia.

Journal: Journal of clinical pharmacology 20010101

Title: Effects of EGIS-7229 (S 21407), a novel class III antiarrhythmic drug, on myocardial refractoriness to electrical stimulation in vivo and in vitro.

Journal: Journal of cardiovascular pharmacology 20010101

Title: Frequency-dependent electrophysiological effects of flecainide, nifekalant and d,l-sotalol on the human atrium.

Journal: Japanese circulation journal 20010101

Title: Developmental toxicity in the pregnant rabbit by the class III antiarrhythmic drug sotalol.

Journal: Pharmacology & toxicology 20010101

Title: The frequency analysis of signal-averaged ECG of P wave as predictor of efficacy of class III antiarrhythmic drugs to maintain sinus rhythm in recurrent idiopathic atrial fibrillation.

Journal: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20010101

Title: Efficacy of sequential antiarrhythmic treatment in sinus rhythm maintenance after successful electrocardioversion in patients with chronic non-valvular atrial fibrillation.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: Sotalol vs metoprolol for ventricular rate control in patients with chronic atrial fibrillation who have undergone digitalization: a single-blinded crossover study.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20010101

Title: Mechanisms of action of antiarrhythmic drugs relative to the origin and perpetuation of cardiac arrhythmias.

Journal: Journal of cardiovascular pharmacology and therapeutics 20010101

Title: Sotalol: the mechanism of its antiarrhythmic-defibrillating effect.

Journal: Cardiovascular drug reviews 20010101

Title: Pharmacologic conversion of atrial fibrillation: a systematic review of available evidence.

Journal: Progress in cardiovascular diseases 20010101

Title: An improved HPLC-fluorescence stereoselective method for analysis of (+)-S- and (-)-R-sotalol enantiomers in plasma sample.

Journal: Bollettino chimico farmaceutico 20010101

Title: Permanent pacing-aid to carry out long-term lithium therapy in manic patient with symptomatic bradycardia.

Journal: Pharmacopsychiatry 20000701

Title: Transmural heterogeneity of ventricular repolarization under baseline and long QT conditions in the canine heart in vivo: torsades de pointes develops with halothane but not pentobarbital anesthesia.

Journal: Journal of cardiovascular electrophysiology 20000301

Title: Effects of chronic treatment by amiodarone on transmural heterogeneity of canine ventricular repolarization in vivo: interactions with acute sotalol.

Journal: Cardiovascular research 19991101

Title: Maintenance of sinus rhythm with oral d,l-sotalol therapy in patients with symptomatic atrial fibrillation and/or atrial flutter. d,l-Sotalol Atrial Fibrillation/Flutter Study Group.

Journal: The American journal of cardiology 19990801

Title: A case of sotalol associated torsades de pointes tachycardia in a 15 month old child.

Journal: Pacing and clinical electrophysiology : PACE 19990101

Title: Two cases of torsades de pointes caused by sotalol therapy.

Journal: Resuscitation 19990101

Title: [Effect of sotalol on systemic hemodynamics and electrophysiology in patients with life-threatening ventricular tachyarrhythmias].

Journal: Zhonghua nei ke za zhi 19990101

Title: [Sotalol--atrial fibrillation, reduced renal function and sudden death].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 19981030

Title: Drug-related torsades de pointes in the isolated rabbit heart: comparison of clofilium, d,l-sotalol, and erythromycin.

Journal: Journal of cardiovascular pharmacology 19980901

Title: T wave alternans after sotalol: evidence for increased sensitivity to sotalol after conversion from atrial fibrillation to sinus rhythm.

Journal: Heart (British Cardiac Society) 19980901

Title: Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications.

Journal: Journal of the American College of Cardiology 19980701

Title: Polymorphic ventricular tachycardias induced by D-sotalol and phenylephrine in canine preparations of atrioventricular block: initiation in the conduction system followed by spatially unstable re-entry.

Journal: Cardiovascular research 19980601

Title: Sotalol associated torsades de pointes tachycardia in a 15-month-old child: successful therapy with magnesium aspartate.

Journal: Pacing and clinical electrophysiology : PACE 19980501

Title: Sotalol associated polymorphic ventricular tachycardia and coronary spasm.

Journal: Heart (British Cardiac Society) 19980501

Title: Thrombolytic activity of beta-adrenolytic drug, sotalol.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 19980301

Title: Inhibition of isoproterenol-induced tachycardia by azimilide in the isolated perfused guinea pig heart.

Journal: Cardiovascular drugs and therapy 19980301

Title: Leukocytoclastic vasculitis associated with sotalol therapy.

Journal: Journal of the American Academy of Dermatology 19980101

Title: Torsade de pointes secondary to d,l-sotalol after catheter ablation of incessant atrioventricular reentrant tachycardia--evidence for a significant contribution of the 'cardiac memory'.

Journal: Clinical cardiology 19980101

Title: Reproducible induction of 'atypical' torsades de pointes by programmed electrical stimulation: a novel form of sotalol-induced proarrhythmia?

Journal: Journal of cardiovascular electrophysiology 19970901

Title: Efficacy and safety of d,l-sotalol in patients with ventricular tachycardia and in survivors of cardiac arrest.

Journal: Journal of the American College of Cardiology 19970801

Title: Efficacy and proarrhythmia with the use of d,l-sotalol for sustained ventricular tachyarrhythmias.

Journal: Journal of cardiovascular pharmacology 19970301

Title: [Iatrogenic collapse; can this be prevented?].

Journal: Nederlands tijdschrift voor geneeskunde 19970208

Title: Successful haemodialysis in sotalol-induced torsade de pointes in a patient with progressive renal failure.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19970201

Title: Sotalol-induced torsades de pointes in patients with renal failure.

Journal: The Canadian journal of cardiology 19970101

Title: Sotalol-induced Torsade de pointes in a CAPD patient--successful treatment with intermittent peritoneal dialysis.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 19970101

Title: Torsades de pointes with administration of high-dose intravenous d-sotalol to a patient with congestive heart failure.

Journal: Pharmacotherapy 19970101

Title: [Noninvasive monitoring of anti-arrhythmia sotalol therapy by analysis of intracardiac signals].

Journal: Biomedizinische Technik. Biomedical engineering 19970101

Title: Atrial flutter with 1:1 conduction after administration of the antimalarial drug mefloquine.

Journal: Clinical cardiology 19961201

Title: Sex difference in risk of torsade de pointes with d,l-sotalol.

Journal: Circulation 19961115

Title: Torsades de pointes from terfenadine and sotalol given in combination.

Journal: Pacing and clinical electrophysiology : PACE 19961001

Title: [Torsade de Pointes tachycardia during sotalol treatment of a patient with normal potassium levels].

Journal: Ugeskrift for laeger 19960708

Title: Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction. The SWORD Investigators. Survival With Oral d-Sotalol.

Journal: Lancet (London, England) 19960706

Title: Torsades de pointes during low-dosage sotalol therapy in haemodialysis patients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19960601

Title: [Sotalol and torsades de pointes ventricular tachycardia].

Journal: Ugeskrift for laeger 19960506

Title: Sotalol proarrhythmia: a report of five cases and an audit of the use of a sotalol in a teaching hospital.

Journal: Australian and New Zealand journal of medicine 19960401

Title: [Sotalol-induced torsade de pointes tachycardia in a 15-month-old infant].

Journal: Zeitschrift fur Kardiologie 19951001

Title: Comparison of sotalol with digoxin-quinidine for conversion of acute atrial fibrillation to sinus rhythm (the Sotalol-Digoxin-Quinidine Trial).

Journal: The American journal of cardiology 19950901

Title: Sotalol-induced bradycardia reversed by glucagon.

Journal: Canadian family physician Medecin de famille canadien 19950401

Title: Intravenous sotalol for the termination of supraventricular tachycardia and atrial fibrillation and flutter: a multicenter, randomized, double-blind, placebo-controlled study. Sotalol Multicenter Study Group.

Journal: American heart journal 19950401

Title: The effect of flunarizine and ryanodine on acquired torsades de pointes arrhythmias in the intact canine heart.

Journal: Journal of cardiovascular electrophysiology 19950301

Title: Clinical implications of pleomorphic ventricular tachycardias on oral sotalol therapy.

Journal: European heart journal 19950301

Title: Multicenter trial of sotalol compared with procainamide in the suppression of inducible ventricular tachycardia: a double-blind, randomized parallel evaluation. Sotalol Multicenter Study Group.

Journal: American heart journal 19950101

Title: Hemodynamic effects and safety of sotalol in the prevention of supraventricular arrhythmias after coronary artery bypass surgery.

Journal: Journal of cardiothoracic and vascular anesthesia 19940801

Title: Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.

Journal: Molecular pharmacology 19940601

Title: [A case report. Sotalol-disopyramide caused asystole].

Journal: Lakartidningen 19940601

Title: Torsade de pointes complicating drug treatment of low-malignant forms of arrhythmia: four cases reports.

Journal: Clinical cardiology 19940401

Title: Comparative effects of the combination of digoxin and dl-sotalol therapy versus digoxin monotherapy for control of ventricular response in chronic atrial fibrillation. dl-Sotalol Atrial Fibrillation Study Group.

Journal: American heart journal 19940301

Title: Response to sotalol predicts the response to amiodarone during serial drug testing in patients with sustained ventricular tachycardia and coronary artery disease.

Journal: The American journal of cardiology 19940215

Title: Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.

Journal: JAMA 19931201

Title: Effect of oral sotalol on systemic hemodynamics and programmed electrical stimulation in patients with ventricular arrhythmias and structural heart disease.

Journal: The American journal of cardiology 19930812

Title: Clinical safety profile of sotalol in the treatment of arrhythmias.

Journal: The American journal of cardiology 19930812

Title: Practical considerations in the use of sotalol for ventricular tachycardia and ventricular fibrillation.

Journal: The American journal of cardiology 19930812

Title: d-sotalol reduces heart rate in vivo through a beta-adrenergic receptor-independent mechanism.

Journal: Clinical pharmacology and therapeutics 19930401

Title: Double-blind trial of aspirin in primary prevention of myocardial infarction in patients with stable chronic angina pectoris. The Swedish Angina Pectoris Aspirin Trial (SAPAT) Group.

Journal: Lancet (London, England) 19921212

Title: Efficacy and safety of sotalol in patients with complex ventricular arrhythmias.

Journal: International journal of cardiology 19921201

Title: Dual chamber rate responsive pacing to allow sotalol therapy for ventricular tachycardia.

Journal: Pacing and clinical electrophysiology : PACE 19921101

Title: Efficacy of flecainide, sotalol, and verapamil in the treatment of right ventricular tachycardia in patients without overt cardiac abnormality.

Journal: British heart journal 19921001

Title: Short- and long-term antiarrhythmic and hemodynamic effects of d,l-sotalol in patients with symptomatic ventricular arrhythmias.

Journal: American heart journal 19920501

Title: Sotalol-induced torsade de pointes: management with magnesium infusion.

Journal: Postgraduate medical journal 19920401

Title: Usefulness of d, I sotalol for suppression of chronic ventricular arrhythmias.

Journal: The American journal of cardiology 19910301

Title: Reduction in QT dispersion by sotalol following myocardial infarction.

Journal: European heart journal 19910301

Title: Sotalol-induced torsades de pointes successfully treated with hemodialysis after failure of conventional therapy.

Journal: American heart journal 19910201

Title: [Hemiparesis and torsade de pointes under low-dose sotalol therapy].

Journal: Schweizerische medizinische Wochenschrift 19900922

Title: Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia.

Journal: Lancet (London, England) 19900915

Title: A mechanism of D-(+)-sotalol effects on heart rate not related to beta-adrenoceptor antagonism.

Journal: British journal of clinical pharmacology 19900801

Title: Serious interactions of sotalol with amiodarone and flecainide.

Journal: The Medical journal of Australia 19900305

Title: Clinical safety profile of sotalol in patients with arrhythmias.

Journal: The American journal of cardiology 19900102

Title: A comparison of sotalol and procainamide in symptomatic ventricular tachycardia.

Journal: Cardiovascular drugs and therapy 19890401

Title: Clinical experience with sotalol in patients with drug-refractory ventricular arrhythmias.

Journal: Journal of the American College of Cardiology 19890101

Title: [Sotalol-induced torsades de pointe in the conscious dog with atrioventricular block. Role of hypokalemia].

Journal: Archives des maladies du coeur et des vaisseaux 19880901

Title: [Ventricular tachyarrhythmia induced by low doses of sotalol: torsade de pointes or polymorphous ventricular tachycardia?].

Journal: Zeitschrift fur Kardiologie 19880601

Title: A normal response to programmed stimulation does not preclude the occurrence of life-threatening torsades de pointes with sotalol.

Journal: European heart journal 19880401

Title: Effect of regression of left ventricular hypertrophy following sotalol therapy on diastolic function in hypertensive patients.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19871201

Title: Sotalol-induced torsades de pointes in a patient with pre-existent normal response to programmed ventricular stimulation.

Journal: European heart journal 19871201

Title: Torsades de pointes induced by sotalol.

Journal: The American journal of cardiology 19871115

Title: Effects of intravenous sotalol in patients with atrioventricular accessory pathways.

Journal: American heart journal 19870901

Title: Effect of beta-adrenoceptor blocking agents on isolation and apomorphine-induced aggression in rodents.

Journal: Indian journal of physiology and pharmacology 19870101

Title: Effect of sotalol, aprindine and their combination on maximum upstroke velocity of action potential in guinea-pig papillary muscle.

Journal: European journal of pharmacology 19861119

Title: [Severe ventricular arrhythmia after ingestion of sotalol. Apropos of 3 cases].

Journal: Therapie 19860101

Title: Torsade de pointes induced by sotalol and hypokalaemia.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 19851012

Title: Electrophysiologic and antiarrhythmic effects of sotalol in patients with life-threatening ventricular tachyarrhythmias.

Journal: Circulation 19850901

Title: Torsade de pointes induced by sotalol.

Journal: British medical journal (Clinical research ed.) 19850824

Title: Torsade de pointes induced by sotalol despite therapeutic plasma sotalol concentrations.

Journal: British medical journal (Clinical research ed.) 19850615

Title: [Possible embryofetopathy caused by beta-blocker (sotalol) taken throughout the pregnancy].

Journal: Pediatrie 19850301

Title: Drug-induced torsade de pointes.

Journal: Clinical pharmacy 19850101

Title: Blood pressure and heart rate response to central beta-blockade in conscious rats with glucocorticoid-induced hypertension.

Journal: Journal of cardiovascular pharmacology 19850101

Title: Sotalol-induced prolongation of the Q-T interval and attacks of unconsciousness.

Journal: International journal of clinical pharmacology, therapy, and toxicology 19840901

Title: Sotalol, hypokalaemia, syncope, and torsade de pointes.

Journal: British heart journal 19840201

Title: Sotalol-induced torsade de pointes.

Journal: American heart journal 19840101

Title: Sotalol-induced torsade de pointes.

Journal: Catheterization and cardiovascular diagnosis 19840101

Title: [Atrioventricular block and torsade de pointes following sotalol overdose].

Journal: La Nouvelle presse medicale 19821225

Title: Sudden versus gradual withdrawal of sotalol in ambulant patients with ischaemic heart disease.

Journal: British heart journal 19821201

Title: Overdrive pacing as treatment of sotalol-induced ventricular tachyarrhythmias (torsade de pointes).

Journal: Acta medica Scandinavica. Supplementum 19820101

Title: Central cholinergic mechanisms in L-DOPA induced hyperactive urinary bladder of the rat.

Journal: Urological research 19820101

Title: Propranolol and sotalol as antagonists of isoproterenol-enhanced physiologic tremor.

Journal: Clinical pharmacology and therapeutics 19810901

Title: Prolongation of the Q-T interval caused by sotalol--possible association with ventricular tachyarrhythmias.

Journal: European heart journal 19810801

Title: Satalol-induced torsade de pointes.

Journal: Postgraduate medical journal 19810501

Title: Reversal of clonidine-induced hypotension by beta-adrenoceptor blocking drugs.

Journal: European journal of pharmacology 19800711

Title: Comparison of the activity and plasma levels of oxprenolol, slow release oxprenolol, long acting propranolol and sotalol.

Journal: European journal of clinical pharmacology 19800601

Title: Proximal myopathy during beta-blockade.

Journal: British medical journal 19791124

Title: Relationship between pharmacokinetics and pharmacodynamics of the beta adrenergic blocking drug sotalol in dogs.

Journal: The Journal of pharmacology and experimental therapeutics 19791101

Title: Cutaneous thickening in hyperthyroidism treated with radioactive iodine and sotalol.

Journal: Lancet (London, England) 19790106

Title: Interaction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye.

Journal: Investigative ophthalmology 19760201

Title: Metabolic responses to catecholamines.

Journal: Acta physiologica latino americana 19760101

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Tags:366-80-3 Molecular Formula|366-80-3 MDL|366-80-3 SMILES|366-80-3 Methanesulfonamide, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-, hydrochloride (1:2)