Home Amines 3687-18-1
3687-18-1,MFCD00008225
Catalog No.:AA003IR3
3687-18-1 | 3-Amino-1-propanesulfonic acid
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5g
98%
in stock  
$12.00   $8.00
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25g
98%
in stock  
$19.00   $13.00
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100g
98%
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$72.00   $50.00
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500g
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  • Technical Information
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Technical Information
Catalog Number:
AA003IR3
Chemical Name:
3-Amino-1-propanesulfonic acid
CAS Number:
3687-18-1
Molecular Formula:
C3H9NO3S
Molecular Weight:
139.1735
MDL Number:
MFCD00008225
IUPAC Name:
3-aminopropane-1-sulfonic acid
InChI:
InChI=1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)
InChI Key:
SNKZJIOFVMKAOJ-UHFFFAOYSA-N
SMILES:
NCCCS(=O)(=O)O
EC Number:
222-977-4
UNII:
5K8EAX0G53
NSC Number:
77071
Properties
Computed Properties
 
Complexity:
133  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
139.03g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
139.169g/mol
Monoisotopic Mass:
139.03g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
88.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.8  

Synonyms
 
3-amino-1-propanesulfonic acid 
3-aminopropanesulfonic acid 
3-aminopropane-1-sulfonic acid 
AJ-26623 
AK208811 
HY-14602 
K349 
SC-17979 
SMR000059181 
SY006704 
AB0006301 
AB1006721 
DB-049023 
Alzhemed 
LS-174627 
TC-063811 
B7446 
FT-0614911 
3-Aminopropane-1-sulfonic Acid (Homotaurine) 
A-2738 
C03349 
D06202 
AB00052207_13 
MFCD00008225 (97+%) 
3-aminopropanesulphonic acid 
687H181 
I05-0199 
Q-200354 
Acamprosate impurity A, European Pharmacopoeia (EP) Reference Standard 
Acamprosate Related Compound A, United States Pharmacopeia (USP) Reference Standard 
A20 
Vivimind 
3-Amino-1,2-propanediol 
D09DLP 
3-Amino-1-propanesulfonicacid 
3APS 
gamma-aminopropanesulfonic acid 
CID1646 
Tramiprosate (stroke), Neurochem 
C3-H9-N-O3-S 
3- aminopropane- 1- sulphonic acid 
NC 758 
LU-02659 
A2602 
Tramiprosate (Alzheimer's disease), Neurochem 
3-Amino-1-propanesulfonic acid, 95% - 1G 1g 
1-Propanesulfonic acid, 3-amino- 
C001355 
Cerebril 
NC-758 
3-aminopropanesulfonic acid 
3-Aminopropane sulfonic acid 
3-Aminopropanesulfonate 
3-aminopropylsulfonic acid 
3-aminopropylsulfonic acid 
C3H9NO3S 
3-APS 
UNII-5K8EAX0G53 
NSC 77071 
Tramiprosate [USAN] 
3-Aminopropane-1-sulphonic acid 
EINECS 222-977-4 
AI3-52544 
5K8EAX0G53 
3-APS 
CHEBI:1457 
CHEMBL149082 
NSC77071 
Tramiprosat 
Tramiprosate (USAN) 
3-Amino-1-propanesulfonic acid, 95% 
MFCD00008225 
Tramiprosate [USAN:INN] 
3-Sulfopropylamine 
NC-531 
homotaurine 
Aminopropanesulfonic-3 
PubChem18251 
Spectrum_001340 
ACMC-209ipe 
Homotaurine; Tramiprosate 
Spectrum2_001409 
Spectrum3_000924 
Spectrum4_001023 
Spectrum5_001319 
3-Aminopropiosulfonic Acid 
tramiprosate 
EC 222-977-4 
AC1L1BX3 
AC1Q54JX 
3 APS 
Lopac0_000066 
SCHEMBL26759 
3-ammoniopropane-1-sulfonate 
KBioGR_001545 
KBioSS_001820 
MLS000028639 
Homotaurine 
DivK1c_000348 
SPECTRUM1501125 
SPBio_001458 
Jsp006555 
3-amino-1-propanesulphonic acid 
3-amino-1-propane sulfonic acid 
CTK3I9761 
HMS501B10 
KBio1_000348 
KBio2_001820 
3-Amino-1-propanesulfonic acid 
KBio2_004388 
KBio2_006956 
KBio3_001928 
1-Propanesulfonic acid,3-amino- 
3-Amino-propane-1-sulfonic acid 
DTXSID80190352 
NINDS_000348 
SNKZJIOFVMKAOJ-UHFFFAOYSA-N 
HMS1921H05 
HMS2235L19 
Tramiprosate 
HMS3372L06 
KS-00000K3A 
ZINC1529636 
ANW-28512 
BDBM50281573 
CCG-39012 
CPD-11725 
NSC-77071 
ZINC01529636 
AKOS006221419 
3687-18-1 
3-Amino-1-propanesulfonic acid, 97% 
CA-1139 
CS-5741 
GS-3103 
LS41859 
RTC-063811 
TRA0073390 
IDI1_000348 
NCGC00094904-01 
NCGC00094904-02 
Literature

Title: High selectivity of the γ-aminobutyric acid transporter 2 (GAT-2, SLC6A13) revealed by structure-based approach.

Journal: The Journal of biological chemistry 20121102

Title: Variable-temperature 17O NMR studies allow quantitative evaluation of molecular dynamics in organic solids.

Journal: Journal of the American Chemical Society 20120905

Title: Acamprosate for treatment of alcohol dependence: mechanisms, efficacy, and clinical utility.

Journal: Therapeutics and clinical risk management 20120101

Title: Metal chaperones: a holistic approach to the treatment of Alzheimer's disease.

Journal: Frontiers in psychiatry 20120101

Title: Alzheimer's disease and the amyloid cascade hypothesis: a critical review.

Journal: International journal of Alzheimer's disease 20120101

Title: Alzheimer's disease: a clinical practice-oriented review.

Journal: Frontiers in neurology 20120101

Title: Probing and trapping a sensitive conformation: amyloid-β fibrils, oligomers, and dimers.

Journal: Journal of Alzheimer's disease : JAD 20120101

Title: Calcium acamprosate: a triclinic polymorph.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: Alzheimer's disease: pathological mechanisms and recent insights.

Journal: Current neuropharmacology 20111201

Title: Current and emerging drug treatment options for Alzheimer's disease: a systematic review.

Journal: Drugs 20111022

Title: Reversed-phase liquid chromatographic determination of tramiprosate in rat plasma using evaporative light scattering detector.

Journal: Biomedical chromatography : BMC 20110801

Title: Precolumn derivatization followed by liquid chromatographic separation and determination of tramiprosate in rat plasma by fluorescence detector: application to pharmacokinetics.

Journal: Journal of pharmaceutical and biomedical analysis 20110515

Title: Gas-phase binding energies for non-covalent Aβ-40 peptide/small molecule complexes from CID mass spectrometry and RRKM theory.

Journal: Physical chemistry chemical physics : PCCP 20110321

Title: Predicting harms and benefits in translational trials: ethics, evidence, and uncertainty.

Journal: PLoS medicine 20110301

Title: Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates.

Journal: Journal of molecular biology 20110225

Title: Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study).

Journal: Archives of medical science : AMS 20110201

Title: Investigational drugs for the treatment of AD: what can we learn from negative trials?

Journal: Alzheimer's research & therapy 20110101

Title: Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment.

Journal: International journal of Alzheimer's disease 20110101

Title: Neurosteroid Binding Sites on the GABA(A) Receptor Complex as Novel Targets for Therapeutics to Reduce Alcohol Abuse and Dependence.

Journal: Advances in pharmacological sciences 20110101

Title: Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease.

Journal: Frontiers in endocrinology 20110101

Title: Determination of the natural abundance δ15N of taurine by gas chromatography-isotope ratio measurement mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20101215

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: The persisting burden of intracerebral haemorrhage: can effective treatments be found?

Journal: PLoS medicine 20101001

Title: Investigation of the noncovalent interactions between anti-amyloid agents and amyloid beta peptides by ESI-MS.

Journal: Journal of the American Society for Mass Spectrometry 20100901

Title: [Progress in the development of anti-amyloid drugs for treatment of Alzheimer's disease.].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100701

Title: Update on the pharmacological treatment of Alzheimer's disease.

Journal: Current neuropharmacology 20100301

Title: Glycine receptors in the nucleus accumbens involved in the ethanol intake-reducing effect of acamprosate.

Journal: Alcoholism, clinical and experimental research 20100101

Title: Simple in vitro assays to identify amyloid-beta aggregation blockers for Alzheimer's disease therapy.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Reciprocal regulation between taurine and glutamate response via Ca2+-dependent pathways in retinal third-order neurons.

Journal: Journal of biomedical science 20100101

Title: Regulation of in vitro Aβ1-40 aggregation mediated by small molecules.

Journal: Journal of Alzheimer's disease : JAD 20100101

Title: Domain-specific cognitive effects of tramiprosate in patients with mild to moderate Alzheimer's disease: ADAS-cog subscale results from the Alphase Study.

Journal: The journal of nutrition, health & aging 20091101

Title: Homotaurine: a failed drug for Alzheimer's disease and now a nutraceutical for memory protection.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091101

Title: Homotaurine metabolized to 3-sulfopropanoate in Cupriavidus necator H16: enzymes and genes in a patchwork pathway.

Journal: Journal of bacteriology 20091001

Title: Effect of tramiprosate in patients with mild-to-moderate Alzheimer's disease: exploratory analyses of the MRI sub-group of the Alphase study.

Journal: The journal of nutrition, health & aging 20090601

Title: Drug development for Alzheimer's disease: where are we now and where are we headed?

Journal: The American journal of geriatric pharmacotherapy 20090601

Title: Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer's disease: the ALZHEMED (Tramiprosate) experience.

Journal: The journal of nutrition, health & aging 20090401

Title: Multivalent & multifunctional ligands to beta-amyloid.

Journal: Current pharmaceutical design 20090101

Title: Recent developments in Alzheimer's disease therapeutics.

Journal: BMC medicine 20090101

Title: The effects of taurine, taurine homologs and hypotaurine on cell and membrane antioxidative system alterations caused by type 2 diabetes in rat erythrocytes.

Journal: Advances in experimental medicine and biology 20090101

Title: The effects of taurine, hypotaurine, and taurine homologs on erythrocyte morphology, membrane fluidity and cytoskeletal spectrin alterations due to diabetes, alcoholism and diabetes-alcoholism in the rat.

Journal: Advances in experimental medicine and biology 20090101

Title: Alzheimer's disease therapeutic research: the path forward.

Journal: Alzheimer's research & therapy 20090101

Title: Present and prospective clinical therapeutic regimens for Alzheimer's disease.

Journal: Neuropsychiatric disease and treatment 20080801

Title: [New approaches for the development of anti-Alzheimer's disease drugs based on the cholinergic hypothesis and amyloid hypothesis].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080501

Title: Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate.

Journal: FEMS microbiology letters 20080201

Title: Preventing beta-amyloid fibrillization and deposition: beta-sheet breakers and pathological chaperone inhibitors.

Journal: BMC neuroscience 20080101

Title: Taurine, an inducer for tau polymerization and a weak inhibitor for amyloid-beta-peptide aggregation.

Journal: Neuroscience letters 20071218

Title: Pharmacogenetic aspects of addictive behaviors.

Journal: Dialogues in clinical neuroscience 20071201

Title: Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions.

Journal: Current neuropharmacology 20071201

Title: Current therapeutic options for Alzheimer's disease.

Journal: Current genomics 20071201

Title: Progress update: Pharmacological treatment of Alzheimer's disease.

Journal: Neuropsychiatric disease and treatment 20071001

Title: The amyloid beta ion channel hypothesis of Alzheimer's disease.

Journal: Neuropsychiatric disease and treatment 20071001

Title: Therapies for Alzheimer's disease.

Journal: Nature reviews. Drug discovery 20070501

Title: Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis.

Journal: Neurobiology of aging 20070401

Title: Influences of different developmental periods of taurine supplements on synaptic plasticity in hippocampal CA1 area of rats following prenatal and perinatal lead exposure.

Journal: BMC developmental biology 20070101

Title: Changing the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon.

Journal: Primary care companion to the Journal of clinical psychiatry 20070101

Title: Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau.

Journal: Molecular neurodegeneration 20070101

Title: Acamprosate: a new tool in the battle against alcohol dependence.

Journal: Neuropsychiatric disease and treatment 20061201

Title: A Phase II study targeting amyloid-beta with 3APS in mild-to-moderate Alzheimer disease.

Journal: Neurology 20061128

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20061001

Title: Substrate specificity of the amino acid transporter PAT1.

Journal: Amino acids 20060901

Title: Influence of a proton gradient on the transport kinetics of the H+/amino acid cotransporter PAT1 in Caco-2 cells.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Tramiprosate.

Journal: Drugs of today (Barcelona, Spain : 1998) 20060501

Title: Diazepam inhibits the induction and maintenance of LTP of C-fiber evoked field potentials in spinal dorsal horn of rats.

Journal: Neuropharmacology 20060201

Title: Molecule of the month. Tramiprosate.

Journal: Drug news & perspectives 20060101

Title: A phase 2 study of tramiprosate for cerebral amyloid angiopathy.

Journal: Alzheimer disease and associated disorders 20060101

Title: The regulation of alpha-MSH release by GABA is mediated by a chloride-dependent [Ca2+]c increase in frog melanotrope cells.

Journal: Peptides 20051001

Title: Inhibitors arrest myofibrillogenesis in skeletal muscle cells at early stages of assembly.

Journal: Cell motility and the cytoskeleton 20040901

Title: Taurine-induced long-lasting potentiation in the rat hippocampus shows a partial dissociation from total hippocampal taurine content and independence from activation of known taurine transporters.

Journal: Journal of neurochemistry 20040601

Title: Transport of pharmacologically active proline derivatives by the human proton-coupled amino acid transporter hPAT1.

Journal: The Journal of pharmacology and experimental therapeutics 20040401

Title: Interactions of taurine and structurally related analogues with the GABAergic system and taurine binding sites of rabbit brain.

Journal: British journal of pharmacology 20030301

Title: Effects of sulfur containing amino acids on iron and nitric oxide stimulated catecholamine oxidation.

Journal: Amino acids 20020601

Title: Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release.

Journal: European journal of pharmacology 20020215

Title: Interactions between taurine and ethanol in the central nervous system.

Journal: Amino acids 20020101

Title: Role of K+ -channels in homotaurine-induced analgesia.

Journal: Fundamental & clinical pharmacology 20010601

Title: Synthesis and characterization of N,N-dichlorinated amino acids: taurine, homotaurine, GABA and L-leucine.

Journal: Neurochemical research 20010601

Title: Neurotoxic effect of acamprosate, n-acetyl-homotaurine, in cultured neurons.

Journal: Journal of biomedical science 20010101

Title: Taurine is a weak scavenger of peroxynitrite and does not attenuate sodium nitroprusside toxicity to cells in culture.

Journal: Amino acids 20010101

Title: Treatment of alcohol-dependent outpatients with acamprosate: a clinical review.

Journal: The Journal of clinical psychiatry 20010101

Title: GABAA receptor-mediated positive inotropism in guinea-pig isolated left atria: evidence for the involvement of capsaicin-sensitive nerves.

Journal: British journal of pharmacology 19890501

Title: Baclofen induces catatonia in rats.

Journal: Neuropharmacology 19870901

Title: The effect of peripherally administered GABA on noradrenaline-induced reflex vagal bradycardia in urethane anaesthetized rats.

Journal: General pharmacology 19850101

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