Title: Activation of TRPV3 by Wood Smoke Particles and Roles in Pneumotoxicity.
Journal: Chemical research in toxicology 20180521
Title: TRPM8 activation attenuates inflammatory responses in mouse models of colitis.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20130430
Title: Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice.
Journal: Toxicology letters 20130313
Title: TRPA1-like channels enhance glycinergic transmission in medullary dorsal horn neurons.
Journal: Journal of neurochemistry 20120801
Title: Menthol suppresses nicotinic acetylcholine receptor functioning in sensory neurons via allosteric modulation.
Journal: Chemical senses 20120601
Title: Lumbar intervertebral disc degeneration associated with axial and radiating low back pain in ageing SPARC-null mice.
Journal: Pain 20120601
Title: Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines.
Journal: International journal of oncology 20120501
Title: Modulation of thermoreceptor TRPM8 by cooling compounds.
Journal: ACS chemical neuroscience 20120418
Title: Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material.
Journal: Molecular pharmacology 20120301
Title: Fused piperidines as a novel class of potent and orally available transient receptor potential melastatin type 8 (TRPM8) antagonists.
Journal: Journal of medicinal chemistry 20120223
Title: Effects of antagonists and heat on TRPM8 channel currents in dorsal root ganglion neuron activated by nociceptive cold stress and menthol.
Journal: Neurochemical research 20120201
Title: Supercooling agent icilin blocks a warmth-sensing ion channel TRPV3.
Journal: TheScientificWorldJournal 20120101
Title: CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch.
Journal: PloS one 20120101
Title: The effects of magnetite (Fe₃O₄) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH₃) cells and in RAW 264.7 macrophages.
Journal: International journal of nanomedicine 20120101
Title: The Role of TRP Proteins in Mast Cells.
Journal: Frontiers in immunology 20120101
Title: Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells.
Journal: PloS one 20120101
Title: Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.
Journal: Pharmacology & therapeutics 20110701
Title: A novel role for TRPM8 in visceral afferent function.
Journal: Pain 20110701
Title: TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction.
Journal: Journal of cellular physiology 20110601
Title: The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav 2.2 channels.
Journal: Hippocampus 20110501
Title: Properties and therapeutic potential of transient receptor potential channels with putative roles in adversity: focus on TRPC5, TRPM2 and TRPA1.
Journal: Current drug targets 20110501
Title: Characterization of TRPM8-like channels activated by the cooling agent icilin in the macrophage cell line RAW 264.7.
Journal: The Journal of membrane biology 20110501
Title: Icilin-evoked behavioral stimulation is attenuated by alpha₂-adrenoceptor activation.
Journal: Brain research 20110412
Title: Icilin induces G1 arrest through activating JNK and p38 kinase in a TRPM8-independent manner.
Journal: Biochemical and biophysical research communications 20110304
Title: Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
Journal: Journal of medicinal chemistry 20110113
Title: The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1.
Journal: The Biochemical journal 20110101
Title: Pharmacological and functional properties of TRPM8 channels in prostate tumor cells.
Journal: Pflugers Archiv : European journal of physiology 20110101
Title: TRPM8 and Nav1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons.
Journal: Molecular neurodegeneration 20110101
Title: The transient receptor potential family of ion channels.
Journal: Genome biology 20110101
Title: Cooling-sensitive TRPM8 is thermostat of skin temperature against cooling.
Journal: PloS one 20110101
Title: Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice.
Journal: Molecular pain 20110101
Title: Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines.
Journal: Arthritis research & therapy 20110101
Title: Sensory properties of menthol and smoking topography.
Journal: Tobacco induced diseases 20110101
Title: TRPM8 biology and medicinal chemistry.
Journal: Current topics in medicinal chemistry 20110101
Title: Activation of TRPA1 by membrane permeable local anesthetics.
Journal: Molecular pain 20110101
Title: Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice.
Journal: PloS one 20110101
Title: Role of TRPM8 in dorsal root ganglion in nerve injury-induced chronic pain.
Journal: BMC neuroscience 20110101
Title: [Comparative effects of menthol and icilin on the induced contraction of the smooth muscles of the vas deferens of normal and castrated rats].
Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101
Title: Chronic treatment with NGF induces spontaneous fluctuations of intracellular Ca(2+) in icilin-sensitive dorsal root ganglion neurons of the rat.
Journal: The Journal of veterinary medical science 20101201
Title: Expression of transient receptor potential channel vanilloid (TRPV) 1–4, melastin (TRPM) 5 and 8, and ankyrin (TRPA1) in the normal and methimazole-treated mouse olfactory epithelium.
Journal: Acta oto-laryngologica 20101101
Title: Inhibition of the cardiac L-type calcium channel current by the TRPM8 agonist, (-)-menthol.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20101001
Title: Gating of transient receptor potential melastatin 8 (TRPM8) channels activated by cold and chemical agonists in planar lipid bilayers.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100915
Title: Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8.
Journal: The Journal of biological chemistry 20100827
Title: TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo.
Journal: Pain 20100801
Title: Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Journal: Journal of medicinal chemistry 20100722
Title: Intact cutaneous C fibre afferent properties in mechanical and cold neuropathic allodynia.
Journal: European journal of pain (London, England) 20100701
Title: Grueneberg ganglion neurons are finely tuned cold sensors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100602
Title: (-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels.
Journal: Bioorganic & medicinal chemistry letters 20100501
Title: Modulation of the cold-activated cation channel TRPM8 by surface charge screening.
Journal: The Journal of physiology 20100115
Title: Amiloride-sensitive channels are a major contributor to mechanotransduction in mammalian muscle spindles.
Journal: The Journal of physiology 20100101
Title: The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity.
Journal: Molecular pain 20100101
Title: Estrogen regulation of TRPM8 expression in breast cancer cells.
Journal: BMC cancer 20100101
Title: Characterization of selective TRPM8 ligands and their structure activity response (S.A.R) relationship.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101
Title: Dissociation of μ- and δ-opioid inhibition of glutamatergic synaptic transmission in superficial dorsal horn.
Journal: Molecular pain 20100101
Title: Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons.
Journal: Molecular pain 20100101
Title: Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle.
Journal: Journal of the peripheral nervous system : JPNS 20091201
Title: Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin.
Journal: The Journal of investigative dermatology 20090901
Title: Letter to the editor: 'Is menthol- or icilin-induced vasodilation mediated by the activation of TRPM8?'.
Journal: American journal of physiology. Heart and circulatory physiology 20090801
Title: Involvement of increased expression of transient receptor potential melastatin 8 in oxaliplatin-induced cold allodynia in mice.
Journal: Neuroscience letters 20090717
Title: Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone.
Journal: American journal of physiology. Heart and circulatory physiology 20090601
Title: Primary afferents with TRPM8 and TRPA1 profiles target distinct subpopulations of rat superficial dorsal horn neurones.
Journal: British journal of pharmacology 20090601
Title: Dose-dependent effects of icilin on thermal preference in the hindpaw and face of rats.
Journal: The journal of pain : official journal of the American Pain Society 20090601
Title: Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features.
Journal: Biochimica et biophysica acta 20090501
Title: Icilin-induced wet-dog shakes in rats are dependent on NMDA receptor activation and nitric oxide production.
Journal: Pharmacology, biochemistry, and behavior 20090501
Title: Lipid raft segregation modulates TRPM8 channel activity.
Journal: The Journal of biological chemistry 20090403
Title: Adult rat odontoblasts lack noxious thermal sensitivity.
Journal: Journal of dental research 20090401
Title: Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens.
Journal: Bioorganic & medicinal chemistry 20090215
Title: Inhibition of TRPM8 by icilin distinct from desensitization induced by menthol and menthol derivatives.
Journal: The Journal of biological chemistry 20090213
Title: Pore dilation occurs in TRPA1 but not in TRPM8 channels.
Journal: Molecular pain 20090101
Title: Inorganic polyphosphate modulates TRPM8 channels.
Journal: PloS one 20090101
Title: Evolution of thermal response properties in a cold-activated TRP channel.
Journal: PloS one 20090101
Title: Tumor necrosis factor-alpha (TNF-alpha) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes.
Journal: Molecular pain 20090101
Title: Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.
Journal: Molecular pain 20090101
Title: [Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol].
Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101
Title: Impairment by allyl isothiocyanate of gastric epithelial wound repair through inhibition of ion transporters.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20081201
Title: Inhibition by the cold receptor agonists menthol and icilin of airway smooth muscle contraction.
Journal: Pulmonary pharmacology & therapeutics 20081001
Title: Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels.
Journal: Pakistan journal of pharmaceutical sciences 20081001
Title: TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: pharmacological and genetic evidence.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080730
Title: Comparison of icilin- and cold-evoked responses of spinal neurones, and their modulation of mechanical activity, in a model of neuropathic pain.
Journal: Brain research 20080618
Title: Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8.
Journal: The Journal of pharmacology and experimental therapeutics 20080601
Title: ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.
Journal: Current neuropharmacology 20080301
Title: Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis.
Journal: PLoS biology 20080201
Title: Icilin induces a hyperthermia in rats that is dependent on nitric oxide production and NMDA receptor activation.
Journal: European journal of pharmacology 20080114
Title: Molecular and cellular limits to somatosensory specificity.
Journal: Molecular pain 20080101
Title: Citral sensing by Transient [corrected] receptor potential channels in dorsal root ganglion neurons.
Journal: PloS one 20080101
Title: HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity.
Journal: Molecular pain 20080101
Title: Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine.
Journal: European journal of pharmacology 20071208
Title: Characterisation of TRPM8 as a pharmacophore receptor.
Journal: Cell calcium 20071201
Title: Differential behavioral effect of the TRPM8/TRPA1 channel agonist icilin (AG-3-5).
Journal: European journal of pharmacology 20071201
Title: Plasticity in intact A delta- and C-fibers contributes to cold hypersensitivity in neuropathic rats.
Journal: Neuroscience 20071130
Title: Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer.
Journal: Inflammopharmacology 20071001
Title: A pharmacological study of slowly adapting mechanoreceptors responsive to cold thermal stimulation.
Journal: Neuroscience 20070824
Title: Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids.
Journal: Experimental cell research 20070515
Title: Transient receptor potential channel A1 is directly gated by calcium ions.
Journal: The Journal of biological chemistry 20070504
Title: TRPM8 is required for cold sensation in mice.
Journal: Neuron 20070503
Title: Attenuated cold sensitivity in TRPM8 null mice.
Journal: Neuron 20070503
Title: Modulation of the cold-activated channel TRPM8 by lysophospholipids and polyunsaturated fatty acids.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070321
Title: Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators.
Journal: Cell calcium 20070301
Title: Nalfurafine, the kappa opioid agonist, inhibits icilin-induced wet-dog shakes in rats and antagonizes glutamate release in the dorsal striatum.
Journal: Neuropharmacology 20070301
Title: TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi.
Journal: The Journal of biological chemistry 20070202
Title: Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
Journal: Nature 20070201
Title: Transient receptor potential channel TRPM8 agonists stimulate calcium influx and neurotensin secretion in neuroendocrine tumor cells.
Journal: Neuroendocrinology 20070101
Title: Mice left out in the cold: commentary on the phenotype of TRPM8-nulls.
Journal: Molecular pain 20070101
Title: Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists.
Journal: Molecular pain 20070101
Title: The cold and menthol receptor TRPM8 contains a functionally important double cysteine motif.
Journal: The Journal of biological chemistry 20061208
Title: Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats.
Journal: European journal of pharmacology 20061010
Title: Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes.
Journal: American journal of physiology. Cell physiology 20060901
Title: Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain.
Journal: Current biology : CB 20060822
Title: Functional expression of thermo-transient receptor potential channels in dental primary afferent neurons: implication for tooth pain.
Journal: The Journal of biological chemistry 20060623
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Icilin evokes a dose- and time-dependent increase in glutamate within the dorsal striatum of rats.
Journal: Amino acids 20060501
Title: High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol.
Journal: Nature neuroscience 20060401
Title: Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.
Journal: European journal of pharmacology 20060113
Title: Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations.
Journal: BMC urology 20060101
Title: Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing.
Journal: BMC neuroscience 20060101
Title: Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells.
Journal: The Journal of biological chemistry 20051125
Title: Icilin activates the delta-subunit of the human epithelial Na+ channel.
Journal: Molecular pharmacology 20051001
Title: Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420
Title: EGF suppresses hydrogen peroxide induced Ca2+ influx by inhibiting L-type channel activity in cultured human corneal endothelial cells.
Journal: Experimental eye research 20050201
Title: How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation.
Journal: Molecular pain 20050101
Title: Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor.
Journal: The European journal of neuroscience 20041101
Title: The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel.
Journal: Neuron 20040916
Title: TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040609
Title: Thermosensitive transient receptor potential channels in vagal afferent neurons of the mouse.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040601
Title: Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay.
Journal: British journal of pharmacology 20040201
Title: ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Journal: Cell 20030321
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: A TRP channel that senses cold stimuli and menthol.
Journal: Cell 20020308
Title: Identification of a cold receptor reveals a general role for TRP channels in thermosensation.
Journal: Nature 20020307