Home Fluorides 372198-97-5
372198-97-5,MFCD20526337
Catalog No.:AA00CHSP

372198-97-5 | N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]glycine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%(HPLC)
in stock  
$291.00   $204.00
- +
10mg
≥98%(HPLC)
in stock  
$418.00   $293.00
- +
25mg
≥98%(HPLC)
in stock  
$868.00   $608.00
- +
50mg
≥98%(HPLC)
in stock  
$1,563.00   $1,094.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00CHSP
Chemical Name:
N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]glycine
CAS Number:
372198-97-5
Molecular Formula:
C19H20F3NO3
Molecular Weight:
367.3622
MDL Number:
MFCD20526337
SMILES:
OC(=O)CN(CC[C@H](c1ccccc1)Oc1ccc(cc1)C(F)(F)F)C
Properties
Computed Properties
 
Complexity:
430  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
8  
XLogP3:
1.8  

Literature

Title: The glycine reuptake inhibitor Org24598 and acamprosate reduce ethanol intake in the rat; tolerance development to acamprosate but not to Org24598.

Journal: Addiction biology 20120901

Title: Development of a novel high-throughput assay for the investigation of GlyT-1b neurotransmitter transporter function.

Journal: Combinatorial chemistry & high throughput screening 20060101

Title: Role of glial and neuronal glycine transporters in the control of glycinergic and glutamatergic synaptic transmission in lamina X of the rat spinal cord.

Journal: The Journal of physiology 20040815

Title: The synthesis and SAR of 2-arylsulfanyl-phenyl piperazinyl acetic acids as glyT-1 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20040802

Title: Positive N-methyl-D-aspartate receptor modulation by selective glycine transporter-1 inhibition in the rat dorsal spinal cord in vivo.

Journal: Neuroscience 20040101

Title: Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor.

Journal: Biological psychiatry 20031201

Title: Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine.

Journal: Neuropharmacology 20031001

Title: Glycine modulators in schizophrenia.

Journal: Current opinion in investigational drugs (London, England : 2000) 20020701

Title: Discovery and SAR of org 24598-a selective glycine uptake inhibitor.

Journal: Bioorganic & medicinal chemistry letters 20010806

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:372198-97-5 Molecular Formula|372198-97-5 MDL|372198-97-5 SMILES|372198-97-5 N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]glycine