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375-22-4,MFCD00004171
Catalog No.:AA0038PD

375-22-4 | Heptafluorobutyric Acid

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10g
≥80%
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$42.00   $29.00
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50g
≥80%
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$122.00   $85.00
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100g
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0038PD
Chemical Name:
Heptafluorobutyric Acid
CAS Number:
375-22-4
Molecular Formula:
C4HF7O2
Molecular Weight:
214.0384
MDL Number:
MFCD00004171
SMILES:
OC(=O)C(C(C(F)(F)F)(F)F)(F)F
NSC Number:
820
Properties
Computed Properties
 
Complexity:
217  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.2  

Literature

Title: Perfluoroalkylated substances (PFAS) affect neither estrogen and androgen receptor activity nor steroidogenesis in human cells in vitro.

Journal: Toxicology letters 20180701

Title: Identification of protein tyrosine phosphatase SHP-2 as a new target of perfluoroalkyl acids in HepG2 cells.

Journal: Archives of toxicology 20170401

Title: Poly- and perfluorinated compounds activate human pregnane X receptor.

Journal: Toxicology 20170401

Title: Binding interactions of perfluoroalkyl substances with thyroid hormone transport proteins and potential toxicological implications.

Journal: Toxicology 20160729

Title: Structure-dependent binding and activation of perfluorinated compounds on human peroxisome proliferator-activated receptor γ.

Journal: Toxicology and applied pharmacology 20140915

Title: Evaluation of perfluoroalkyl acid activity using primary mouse and human hepatocytes.

Journal: Toxicology 20130607

Title: In vitro toxicological characterization of perfluorinated carboxylic acids with different carbon chain lengths.

Journal: Toxicology letters 20130412

Title: Electrochemical mineralization of perfluorocarboxylic acids (PFCAs) by ce-doped modified porous nanocrystalline PbO2 film electrode.

Journal: Environmental science & technology 20120918

Title: Perfluorinated compounds in surface water and organisms from Baiyangdian Lake in North China: source profiles, bioaccumulation and potential risk.

Journal: Bulletin of environmental contamination and toxicology 20120901

Title: A quantitative liquid chromatography tandem mass spectrometry method for metabolomic analysis of Plasmodium falciparum lipid related metabolites.

Journal: Analytica chimica acta 20120820

Title: Analysis of perfluoroalkyl substances in waters from Germany and Spain.

Journal: The Science of the total environment 20120801

Title: Toxicological evaluation of ammonium perfluorobutyrate in rats: twenty-eight-day and ninety-day oral gavage studies.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20120701

Title: Protic ionic liquids with fluorous anions: physicochemical properties and self-assembly nanostructure.

Journal: Physical chemistry chemical physics : PCCP 20120614

Title: Behavior of perfluorinated compounds in soils during leaching experiments.

Journal: Chemosphere 20120501

Title: 5:3 Polyfluorinated acid aerobic biotransformation in activated sludge via novel 'one-carbon removal pathways'.

Journal: Chemosphere 20120401

Title: [Analysis of aliphatic carboxylic acids in anaerobic digestion process waters by ion-exclusion chromatography].

Journal: Se pu = Chinese journal of chromatography 20120401

Title: Quantification of vitamin B6 vitamers in human cerebrospinal fluid by ultra performance liquid chromatography-tandem mass spectrometry.

Journal: Analytica chimica acta 20120127

Title: Occurrence of perfluoroalkyl compounds in surface waters from the North Pacific to the Arctic Ocean.

Journal: Environmental science & technology 20120117

Title: Toxicity of polyfluorinated and perfluorinated compounds to lettuce (Lactuca sativa) and green algae (Pseudokirchneriella subcapitata).

Journal: Archives of environmental contamination and toxicology 20120101

Title: Transcriptional effects of perfluorinated compounds in rat hepatoma cells.

Journal: Chemosphere 20120101

Title: The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Journal: PloS one 20120101

Title: Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells.

Journal: PloS one 20120101

Title: Effect of the leaving group and solvent combination on the LFER reaction constants.

Journal: International journal of molecular sciences 20120101

Title: Beneficial effects of long-term administration of an oral formulation of Angiotensin-(1-7) in infarcted rats.

Journal: International journal of hypertension 20120101

Title: Destabilization of the outer and inner mitochondrial membranes by core and linker histones.

Journal: PloS one 20120101

Title: Comparison of ion balance and nitrogen metabolism in old and young leaves of alkali-stressed rice plants.

Journal: PloS one 20120101

Title: The detection and quantification of ethyl glucuronide in placental tissue and placental perfusate by headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry.

Journal: Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharamcologie clinique 20120101

Title: Role of medium- and short-chain L-3-hydroxyacyl-CoA dehydrogenase in the regulation of body weight and thermogenesis.

Journal: Endocrinology 20111201

Title: Isomer profiles of perfluorochemicals in matched maternal, cord, and house dust samples: manufacturing sources and transplacental transfer.

Journal: Environmental health perspectives 20111101

Title: Cooperative effect in ion pairing of oligolysine with heptafluorobutyric acid in reversed-phase chromatography.

Journal: Journal of chromatography. A 20111028

Title: Analysis of a homologous series of perfluorocarboxylates from American Red Cross adult blood donors, 2000-2001 and 2006.

Journal: Environmental science & technology 20111001

Title: Glycosyl part identified within Balanites aegyptiaca fruit protease.

Journal: International journal of biological macromolecules 20111001

Title: Perfluoroalkyl and polyfluoroalkyl substances in the environment: terminology, classification, and origins.

Journal: Integrated environmental assessment and management 20111001

Title: Determination of 4(5)-methylimidazole in soy sauce and other foods by LC-MS/MS after solid-phase extraction.

Journal: Journal of agricultural and food chemistry 20110928

Title: Quantitation of quinapril in human plasma by matrix-assisted laser desorption ionization time-of-flight mass spectrometry with quinolone matrix additives.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110915

Title: [Simultaneous determination of 20 underivatized amino acids by high performance liquid chromatography-evaporative light-scattering detection].

Journal: Se pu = Chinese journal of chromatography 20110901

Title: N-Glycosylation influences the structure and self-association abilities of recombinant nucleolin.

Journal: The FEBS journal 20110701

Title: Development and validation of an ultra-high performance liquid chromatography-tandem mass-spectrometry (UHPLC-MS/MS) method for the simultaneous determination of neurotransmitters in rat brain samples.

Journal: Journal of neuroscience methods 20110615

Title: Impact of solvent conditions on separation and detection of basic drugs by micro liquid chromatography-mass spectrometry under overloading conditions.

Journal: Journal of chromatography. A 20110603

Title: Targeted identification of metastasis-associated cell-surface sialoglycoproteins in prostate cancer.

Journal: Molecular & cellular proteomics : MCP 20110601

Title: A novel strategy to isolate ubiquitin conjugates reveals wide role for ubiquitination during neural development.

Journal: Molecular & cellular proteomics : MCP 20110501

Title: An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect.

Journal: Clinics (Sao Paulo, Brazil) 20110501

Title: Effects of perfluoroalkyl compounds on mRNA expression levels of thyroid hormone-responsive genes in primary cultures of avian neuronal cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401

Title: Sorption of perfluorochemicals to granular activated carbon in the presence of ultrasound.

Journal: The journal of physical chemistry. A 20110324

Title: Exploring indirect sources of human exposure to perfluoroalkyl carboxylates (PFCAs): evaluating uptake, elimination, and biotransformation of polyfluoroalkyl phosphate esters (PAPs) in the rat.

Journal: Environmental health perspectives 20110301

Title: Liquid chromatography-tandem mass spectrometry detection of the quaternary ammonium compound mebezonium as an active ingredient in t61.

Journal: Journal of analytical toxicology 20110301

Title: Enzymatic shaving of the tegument surface of live schistosomes for proteomic analysis: a rational approach to select vaccine candidates.

Journal: PLoS neglected tropical diseases 20110301

Title: Rhodium-catalyzed synthesis of 2,3-disubstituted indoles from β,β-disubstituted stryryl azides.

Journal: Angewandte Chemie (International ed. in English) 20110211

Title: Simultaneous determination of six analytes by HPLC-UV for high throughput analysis in permeability assessment.

Journal: Journal of chromatographic science 20110201

Title: Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes.

Journal: The Journal of biological chemistry 20110114

Title: Structure-activity relationship assessment of four perfluorinated chemicals using a prolonged zebrafish early life stage test.

Journal: Chemosphere 20110101

Title: Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling.

Journal: Fibrogenesis & tissue repair 20110101

Title: Polyamine analysis by LC-MS.

Journal: Methods in molecular biology (Clifton, N.J.) 20110101

Title: Analysis of common and specific mechanisms of liver function affected by nitrotoluene compounds.

Journal: PloS one 20110101

Title: Insights on the evolution of prolyl 3-hydroxylation sites from comparative analysis of chicken and Xenopus fibrillar collagens.

Journal: PloS one 20110101

Title: Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies.

Journal: PloS one 20110101

Title: Stable differences in intrinsic mitochondrial membrane potential of tumor cell subpopulations reflect phenotypic heterogeneity.

Journal: International journal of cell biology 20110101

Title: Adsorption of four perfluorinated acids on non ion exchange polymer sorbents.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20110101

Title: Toxicity and Molecular Identification of Green Toadfish Lagocephalus lunaris Collected from Kyushu Coast, Japan.

Journal: Journal of toxicology 20110101

Title: Analytical challenges: determination of tetrodotoxin in human urine and plasma by LC-MS/MS.

Journal: Marine drugs 20110101

Title: Structural analysis of fungal cerebrosides.

Journal: Frontiers in microbiology 20110101

Title: Assessment of monacolin in the fermented products using Monascus purpureus FTC5391.

Journal: Journal of biomedicine & biotechnology 20110101

Title: The ratio 1660/1690 cm(-1) measured by infrared microspectroscopy is not specific of enzymatic collagen cross-links in bone tissue.

Journal: PloS one 20110101

Title: Sunitinib Inhibits Cell Proliferation and Alters Steroidogenesis by Down-Regulation of HSD3B2 in Adrenocortical Carcinoma Cells.

Journal: Frontiers in endocrinology 20110101

Title: Microbial biodegradation of a novel fluorotelomer alcohol, 1H,1H,2H,2H,8H,8H-perfluorododecanol, yields short fluorinated acids.

Journal: Applied microbiology and biotechnology 20101101

Title: Relationship between Pentosidine and Pyridinoline Levels in Human Diabetic Cataract Lenses.

Journal: Journal of clinical biochemistry and nutrition 20101101

Title: Interdependent phosphorylation within the kinase domain T-loop Regulates CHK2 activity.

Journal: The Journal of biological chemistry 20101022

Title: Distribution and sources of polyfluoroalkyl substances (PFAS) in the River Rhine watershed.

Journal: Environmental pollution (Barking, Essex : 1987) 20101001

Title: Brominated flame retardants and perfluorinated compounds in indoor dust from homes and offices in Flanders, Belgium.

Journal: Chemosphere 20100901

Title: Quantification of immature and mature collagen crosslinks by liquid chromatography-electrospray ionization mass spectrometry in connective tissues.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601

Title: Determination of perfluorinated compounds in the upper Mississippi river basin.

Journal: Environmental science & technology 20100601

Title: Polyfluoroalkyl compounds in landfill leachates.

Journal: Environmental pollution (Barking, Essex : 1987) 20100501

Title: Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination Survey.

Journal: Environmental health perspectives 20100501

Title: Wet deposition of poly- and perfluorinated compounds in Northern Germany.

Journal: Environmental pollution (Barking, Essex : 1987) 20100501

Title: Determination of aminoglycoside and macrolide antibiotics in meat by pressurized liquid extraction and LC-ESI-MS.

Journal: Journal of separation science 20100301

Title: Steroid assays in paediatric endocrinology.

Journal: Journal of clinical research in pediatric endocrinology 20100301

Title: Sources of polyfluoroalkyl compounds in the North Sea, Baltic Sea and Norwegian Sea: Evidence from their spatial distribution in surface water.

Journal: Marine pollution bulletin 20100201

Title: Carbohydrate analysis throughout the development of a protein therapeutic.

Journal: Glycoconjugate journal 20100201

Title: Application of perfluorinated acids as ion-pairing reagents for reversed-phase chromatography and retention-hydrophobicity relationships studies of selected beta-blockers.

Journal: Journal of chromatography. A 20100122

Title: A novel method for sample preparation of fresh lung cancer tissue for proteomics analysis by tumor cell enrichment and removal of blood contaminants.

Journal: Proteome science 20100101

Title: The zebra finch neuropeptidome: prediction, detection and expression.

Journal: BMC biology 20100101

Title: Male accessory gland protein reduces egg laying in a simultaneous hermaphrodite.

Journal: PloS one 20100101

Title: Characterization of a diverse secretome generated by the mouse preimplantation embryo in vitro.

Journal: Reproductive biology and endocrinology : RB&E 20100101

Title: Inhibition of methylglyoxal-mediated protein modification in glyoxalase I overexpressing mouse lenses.

Journal: Journal of ophthalmology 20100101

Title: Developmental effects of perfluorononanoic Acid in the mouse are dependent on peroxisome proliferator-activated receptor-alpha.

Journal: PPAR research 20100101

Title: Gene Expression Profiling in Wild-Type and PPARα-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPARα-Independent Effects.

Journal: PPAR research 20100101

Title: Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells.

Journal: PloS one 20100101

Title: Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101

Title: GC separation of amino acid enantiomers via derivatization with heptafluorobutyl chloroformate and Chirasil-L-Val column.

Journal: Journal of separation science 20091101

Title: Organic anion transporting polypeptide (Oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of Oatp1a1 in renal elimination of perfluorocarboxylates in rats.

Journal: Toxicology letters 20091028

Title: Separation of polar betalain pigments from cacti fruits of Hylocereus polyrhizus by ion-pair high-speed countercurrent chromatography.

Journal: Journal of chromatography. A 20091009

Title: Structure-activity relationships and human relevance for perfluoroalkyl acid-induced transcriptional activation of peroxisome proliferation in liver cell cultures.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090901

Title: Solvolytic reactivity of heptafluorobutyrates and trifluoroacetates.

Journal: The Journal of organic chemistry 20090821

Title: Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC-MS/MS and evaluation of their stability in mice tissues.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715

Title: Underivatized polyamine analysis in plant samples by ion pair LC coupled with electrospray tandem mass spectrometry.

Journal: Plant physiology and biochemistry : PPB 20090701

Title: Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-alpha.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090701

Title: Modulation of morphology and conductivity of mixed-valence tetrathiafulvalene nanofibers by coexisting organic acid anions.

Journal: Langmuir : the ACS journal of surfaces and colloids 20090616

Title: C(1) compounds as auxiliary substrate for engineered Pseudomonas putida S12.

Journal: Applied microbiology and biotechnology 20090601

Title: Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20090501

Title: Identification and characterization of neuronal mitogen-activated protein kinase substrates using a specific phosphomotif antibody.

Journal: Molecular & cellular proteomics : MCP 20090401

Title: Differential expression of a virulence factor in pathogenic and non-pathogenic mycobacteria.

Journal: Molecular microbiology 20090401

Title: Structure-activity-dependent regulation of cell communication by perfluorinated fatty acids using in vivo and in vitro model systems.

Journal: Environmental health perspectives 20090401

Title: High-performance liquid chromatographic determination of chlorhexidine in whole blood by solid-phase extraction and kinetics following an intravenous infusion in rats.

Journal: Journal of analytical toxicology 20090301

Title: Reductive defluorination of aqueous perfluorinated alkyl surfactants: effects of ionic headgroup and chain length.

Journal: The journal of physical chemistry. A 20090129

Title: Histone H3 tail clipping regulates gene expression.

Journal: Nature structural & molecular biology 20090101

Title: Barometric sensitive coatings based upon osmium complexes dissolved in a fluoroacrylic polymer.

Journal: Analytical chemistry 20090101

Title: Malaria parasite invasion of the mosquito salivary gland requires interaction between the Plasmodium TRAP and the Anopheles saglin proteins.

Journal: PLoS pathogens 20090101

Title: Phosphorylation regulates human T-cell leukemia virus type 1 Rex function.

Journal: Retrovirology 20090101

Title: Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia.

Journal: Critical care (London, England) 20090101

Title: HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase.

Journal: The Journal of biological chemistry 20081226

Title: Simultaneous detection and quantitation of highly water-soluble herbicides in serum using ion-pair liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081215

Title: Quantitative determination of spinosin in rat plasma by liquid chromatography-tandem mass spectrometry method.

Journal: Journal of pharmaceutical and biomedical analysis 20081201

Title: Quantitative determination of glycopyrrolate in human plasma by liquid chromatography-electrospray ionization mass spectrometry: the use of a volatile ion-pairing agent during both liquid-liquid extraction and liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081201

Title: Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081101

Title: Separation of Amadori peptides from their unmodified analogs by ion-pairing RP-HPLC with heptafluorobutyric acid as ion-pair reagent.

Journal: Analytical and bioanalytical chemistry 20081101

Title: Quantification of amino acid ionic liquids using liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20081024

Title: A fully validated isotope dilution HPLC-MS/MS method for the simultaneous determination of succinylcholine and succinylmonocholine in serum and urine samples.

Journal: Journal of mass spectrometry : JMS 20081001

Title: Isolation and identification of the Amanita muscaria and Amanita pantherina toxins in human urine.

Journal: Neuro endocrinology letters 20081001

Title: Quantitative determination of underivatized polyamines by using isotope dilution RP-LC-ESI-MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis 20080929

Title: Identification of c-Src tyrosine kinase substrates using mass spectrometry and peptide microarrays.

Journal: Journal of proteome research 20080905

Title: Effects of perfluorobutyrate exposure during pregnancy in the mouse.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080901

Title: The influence of carbon-carbon multiple bonds on the solvolyses of tertiary alkyl halides: A Grunwald-Winstein analysis.

Journal: International journal of molecular sciences 20080901

Title: Comparative pharmacokinetics of perfluorobutyrate in rats, mice, monkeys, and humans and relevance to human exposure via drinking water.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080701

Title: Analysis of glutamine, glutamate, pyroglutamate, and GABA in cerebrospinal fluid using ion pairing HPLC with positive electrospray LC/MS/MS.

Journal: Journal of neuroscience methods 20080630

Title: Preconcentration and decomposition of perfluorinated carboxylic acids on an activated charcoal cartridge with sodium biphenyl reagent and its determination at microg L(-1) level on the basis of flow injection-fluorimetric detection of fluoride ion.

Journal: Talanta 20080215

Title: Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.

Journal: The EMBO journal 20080109

Title: Single-laboratory validation of a liquid chromatographic/tandem mass spectrometric method for the determination of free and total carnitine in infant formula and raw ingredients.

Journal: Journal of AOAC International 20080101

Title: Neuropeptide receptor transcriptome reveals unidentified neuroendocrine pathways.

Journal: PloS one 20080101

Title: Physical and in silico approaches identify DNA-PK in a Tax DNA-damage response interactome.

Journal: Retrovirology 20080101

Title: Sample prep for proteomics of breast cancer: proteomics and gene ontology reveal dramatic differences in protein solubilization preferences of radioimmunoprecipitation assay and urea lysis buffers.

Journal: Proteome science 20080101

Title: Analysis of underivatized polyamines by reversed phase liquid chromatography with electrospray tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20071130

Title: Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS).

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101

Title: Simultaneous determination of flavonoid and alkaloid compounds in Citrus herbs by high-performance liquid chromatography-photodiode array detection-electrospray mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071001

Title: Perfluoroalkyl acids: what is the evidence telling us?

Journal: Environmental health perspectives 20070501

Title: [Photodegradation of perfluorinated carboxylic acids by 185 nm VUV light].

Journal: Huan jing ke xue= Huanjing kexue 20070401

Title: Light-induced degradation of perfluorocarboxylic acids in the presence of titanium dioxide.

Journal: Chemosphere 20070301

Title: Occurrence of perfluorooctane sulfonate and other perfluorinated alkylated substances in harbor porpoises from the Black Sea.

Journal: Environmental science & technology 20070101

Title: Photodegradation of perfluorooctanoic acid by 185 nm vacuum ultraviolet light.

Journal: Journal of environmental sciences (China) 20070101

Title: Proteomics reveals multiple routes to the osteogenic phenotype in mesenchymal stem cells.

Journal: BMC genomics 20070101

Title: Capillary scale monolithic trap column for desalting and preconcentration of peptides and proteins in one- and two-dimensional separations.

Journal: Journal of chromatography. A 20061215

Title: Reliable on-line sample preparation of basic compounds from plasma using a reversed phase restricted access media in column-switching LC.

Journal: Journal of pharmaceutical and biomedical analysis 20061116

Title: Selenium speciation in dill (Anethum graveolens L.) by ion pairing reversed phase and cation exchange HPLC with ICP-MS detection.

Journal: Talanta 20061115

Title: Quantification and confirmation of anionic, cationic and neutral pesticides and transformation products in water by on-line solid phase extraction-liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20061110

Title: Dirhodium(II) tetrakis(perfluorobutyrate)-catalyzed 1,4-hydrosilylation of alpha,beta-unsaturated carbonyl compounds.

Journal: Chemical & pharmaceutical bulletin 20061101

Title: Analysis for perfluorocarboxylic acids/anions in surface waters and precipitation using GC--MS and analysis of PFOA from large-volume samples.

Journal: Environmental science & technology 20061015

Title: LC/MS/MS analysis of quaternary ammonium drugs and herbicides in whole blood.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061002

Title: An analytical strategy for quaternary ammonium neuromuscular blocking agents in a forensic setting using LC-MS/MS on a tandem quadrupole/time-of-flight instrument.

Journal: Journal of the American Society for Mass Spectrometry 20061001

Title: Histone proteins determined in a human colon cancer by high-performance liquid chromatography and mass spectrometry.

Journal: Journal of chromatography. A 20060929

Title: Context-dependent effects on the hydrophilicity/hydrophobicity of side-chains during reversed-phase high-performance liquid chromatography: Implications for prediction of peptide retention behaviour.

Journal: Journal of chromatography. A 20060901

Title: Novel configurational structures of sodium tetrakis(3-heptafluorobutylryl-(+)-camphorato) Ln(III) complexes with a trapped Na+ by Na+...FC interactions in the solid state and in solution.

Journal: Inorganic chemistry 20060807

Title: Adsorption at liquid interfaces: the generalized Langmuir isotherm and interfacial structure.

Journal: The journal of physical chemistry. B 20060615

Title: Analysis of etimicin sulfate by liquid chromatography with pulsed amperometric detection.

Journal: Journal of chromatography. A 20060519

Title: Evaluation of porous graphitic carbon stationary phase for simultaneous preconcentration and separation of organic and inorganic selenium species in 'clean' water systems.

Journal: Journal of chromatography. A 20060505

Title: Ion-interaction-capillary zone electrophoresis of cationic proteomic peptide standards.

Journal: Journal of chromatography. A 20060414

Title: Atmospheric chemistry of N-methyl perfluorobutane sulfonamidoethanol, C4F9SO2N(CH3)CH2CH2OH: kinetics and mechanism of reaction with OH.

Journal: Environmental science & technology 20060315

Title: Evaluation of volatile ion-pair reagents for the liquid chromatography-mass spectrometry analysis of polar compounds and its application to the determination of methadone in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20060224

Title: Analysis of monosaccharides, fatty constituents and rare O-acetylated sialic acids from gonads of the starfish Asterias rubens.

Journal: Biochimie 20060201

Title: Measurement of stable isotopic enrichment and concentration of long-chain fatty acyl-carnitines in tissue by HPLC-MS.

Journal: Journal of lipid research 20060201

Title: Phosphorylation analysis by mass spectrometry: myths, facts, and the consequences for qualitative and quantitative measurements.

Journal: Molecular & cellular proteomics : MCP 20060101

Title: Identification of neuroactive steroids and their precursors and metabolites in adult male rat brain.

Journal: Endocrinology 20060101

Title: Proteomic analysis of nipple aspirate fluid from women with early-stage breast cancer using isotope-coded affinity tags and tandem mass spectrometry reveals differential expression of vitamin D binding protein.

Journal: BMC cancer 20060101

Title: Knock-out of SO1377 gene, which encodes the member of a conserved hypothetical bacterial protein family COG2268, results in alteration of iron metabolism, increased spontaneous mutation and hydrogen peroxide sensitivity in Shewanella oneidensis MR-1.

Journal: BMC genomics 20060101

Title: Structural analysis of naturally occurring sialic acids.

Journal: Methods in molecular biology (Clifton, N.J.) 20060101

Title: Syntheses of new androstane brassinosteroids with 17beta-ester groups--butyrates, heptafluorobutyrates, and laurates.

Journal: Steroids 20051001

Title: Tissue distribution of perfluorinated chemicals in harbor seals (Phoca vitulina) from the Dutch Wadden Sea.

Journal: Environmental science & technology 20050915

Title: Separation and detection of phosphorylated and nonphosphorylated peptides in liquid chromatography-mass spectrometry using monolithic columns and acidic or alkaline mobile phases.

Journal: Analytical chemistry 20050715

Title: Multianalyte quantification of vitamin B6 and B2 species in the nanomolar range in human plasma by liquid chromatography-tandem mass spectrometry.

Journal: Clinical chemistry 20050701

Title: Effect of anionic ion-pairing reagent hydrophobicity on selectivity of peptide separations by reversed-phase liquid chromatography.

Journal: Journal of chromatography. A 20050701

Title: GC/MS identification and quantification of constituents of bacterial lipids and glycoconjugates obtained after methanolysis as heptafluorobutyrate derivatives.

Journal: Analytical biochemistry 20050515

Title: Effects of chromatography conditions on intact protein separations for top-down proteomics.

Journal: Journal of chromatography. A 20050506

Title: Nucleolin undergoes partial N- and O-glycosylations in the extranuclear cell compartment.

Journal: Biochemistry 20050419

Title: Silver(I) compounds consisting of [2.2]paracyclophane: reversible guest-driven solid-state transformation and incorporation behavior.

Journal: Inorganic chemistry 20050321

Title: The zebrafish progranulin gene family and antisense transcripts.

Journal: BMC genomics 20050101

Title: Chronobiological analysis and mass spectrometric characterization of pigment-dispersing factor in the cockroach Leucophaea maderae.

Journal: Journal of insect science (Online) 20050101

Title: A sensitive and specific HPLC method for the determination of total pentosidine concentration in plasma.

Journal: Journal of biochemical and biophysical methods 20041130

Title: Enhancement of evaporative light scattering detection in high-performance liquid chromatographic determination of neomycin based on highly volatile mobile phase, high-molecular-mass ion-pairing reagents and controlled peak shape.

Journal: Journal of chromatography. A 20041119

Title: Validation of ion chromatography for human salivary anionic analysis.

Journal: Archives of oral biology 20041101

Title: Human salivary anionic analysis using ion chromatography.

Journal: Archives of oral biology 20041101

Title: Diagnosis of chronic alcohol consumption. Hair analysis for ethyl-glucuronide.

Journal: Forensic science international 20041029

Title: Operational variables in high-performance liquid chromatography-electrospray ionization mass spectrometry of peptides and proteins using poly(styrene-divinylbenzene) monoliths.

Journal: Journal of chromatography. A 20041022

Title: Development of an analytical reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometry method for characterization of recombinant antibodies.

Journal: Journal of chromatography. A 20041022

Title: Determination of paraquat and diquat in human body fluids by high-performance liquid chromatography/tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20041001

Title: Optimization of diagonal chromatography for recognizing post-translational modifications.

Journal: Journal of chromatography. A 20040827

Title: Quantitative gas chromatography/mass spectrometry determination of C-mannosylation of tryptophan residues in glycoproteins.

Journal: Analytical biochemistry 20040615

Title: Liquid chromatography/quadrupole time-of-flight mass spectrometry for determination of saxitoxin and decarbamoylsaxitoxin in shellfish.

Journal: Journal of chromatography. A 20040521

Title: Influence of perfluorinated carboxylic acids on ion-pair reversed-phase high-performance liquid chromatographic separation of betacyanins and 17-decarboxy-betacyanins.

Journal: Journal of chromatography. A 20040312

Title: Identification and characterization of Se-methyl selenomethionine in Brassica juncea roots.

Journal: Journal of chromatography. A 20040213

Title: Sequential GC/MS analysis of sialic acids, monosaccharides, and amino acids of glycoproteins on a single sample as heptafluorobutyrate derivatives.

Journal: Biochemistry 20030715

Title: Analytical method for the determination of the aminoglycoside gentamicin in hospital wastewater via liquid chromatography-electrospray-tandem mass spectrometry.

Journal: Journal of chromatography. A 20030606

Title: Separation and detection of siderophores produced by marine bacterioplankton using high-performance liquid chromatography with electrospray ionization mass spectrometry.

Journal: Analytical chemistry 20030601

Title: Heteroconjugation-based capillary electrophoretic separation of phenolic compounds in acetonitrile and propylene carbonate.

Journal: Electrophoresis 20030501

Title: Derivatisation and gas chromatography-chemical ionisation mass spectrometry of selected synthetic and natural endocrine disruptive chemicals.

Journal: Journal of chromatography. A 20030328

Title: Effect of the mobile phase composition on the separation and detection of intact proteins by reversed-phase liquid chromatography-electrospray mass spectrometry.

Journal: Journal of chromatography. A 20020531

Title: Gas-chromatography/mass-spectrometry analysis of human skin constituents as heptafluorobutyrate derivatives with special reference to long-chain bases.

Journal: Journal of lipid research 20020501

Title: Toxicological analysis of chlorhexidine in human serum using HPLC on a polymer-coated ODS column.

Journal: Journal of analytical toxicology 20020301

Title: HPLC simultaneous determination of glycerol and mannitol in human tissues for forensic analysis.

Journal: Forensic science international 20020218

Title: A parallel processing solid phase extraction protocol for the determination of whole blood folate.

Journal: Analytical biochemistry 20020201

Title: Selenium speciation by HPLC with tandem mass spectrometric detection.

Journal: Analytical and bioanalytical chemistry 20020201

Title: Studies of signal suppression in liquid chromatography-electrospray ionization mass spectrometry using volatile ion-pairing reagents.

Journal: Journal of chromatography. A 20011207

Title: Diversity of sialic acids revealed using gas chromatography/mass spectrometry of heptafluorobutyrate derivatives.

Journal: Glycobiology 20010801

Title: Electrospray ionization mass spectrometry of tetrodotoxin and its analogs: liquid chromatography/mass spectrometry, tandem mass spectrometry, and liquid chromatography/tandem mass spectrometry.

Journal: Analytical biochemistry 20010301

Title: Determination of chlormequat in fruit samples by liquid chromatography-electrospray-mass spectrometry/mass spectrometry.

Journal: Journal of AOAC International 20010101

Title: Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus.

Journal: BMC biochemistry 20010101

Application
The employment of Perfluorobutyric acid represents a significant advancement in the field of high-performance liquid chromatography (HPLC), particularly in enhancing the selectivity of histone protein analysis. Acting as a mobile phase modifier, Perfluorobutyric acid aids in the optimization of chromatographic separation, thereby facilitating the precise identification and quantification of histone proteins. Additionally, Perfluorobutyric acid serves as an essential ion pairing reagent in both preparative and analytical reserved phase HPLC methodologies for underivatized peptides. Through its strategic application, Perfluorobutyric acid enables the efficient isolation and purification of peptides, contributing to the elucidation of complex biological samples. This utilization underscores its significance as a versatile chemical tool in chromatographic techniques, ultimately advancing our understanding of biomolecular interactions and enabling the characterization of intricate biological systems with heightened accuracy and resolution.
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SDS
Tags:375-22-4 Molecular Formula|375-22-4 MDL|375-22-4 SMILES|375-22-4 Heptafluorobutyric Acid |Fluorinated_Building_Blocks