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37680-73-2,MFCD00055553
Catalog No.:AA00ILHI

37680-73-2 | 1,1'-Biphenyl, 2,2',4,5,5'-pentachloro-

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10mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ILHI
Chemical Name:
1,1'-Biphenyl, 2,2',4,5,5'-pentachloro-
CAS Number:
37680-73-2
Molecular Formula:
C12H5Cl5
Molecular Weight:
326.4331
MDL Number:
MFCD00055553
SMILES:
Clc1ccc(c(c1)c1cc(Cl)c(cc1Cl)Cl)Cl
Properties
Computed Properties
 
Complexity:
259  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Rotatable Bond Count:
1  
XLogP3:
6.5  

Literature

Title: Liver Disease in a Residential Cohort With Elevated Polychlorinated Biphenyl Exposures.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20180701

Title: Possible mechanism for the polychlorinated bipheny-linduced liver-selective accumulation of thyroxine in rats.

Journal: The Journal of toxicological sciences 20170101

Title: Maternal exposure to a mixture of di(2-ethylhexyl) phthalate (DEHP) and polychlorinated biphenyls (PCBs) causes reproductive dysfunction in adult male mouse offspring.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20161001

Title: Lactational exposure of mice to low levels of non-dioxin-like polychlorinated biphenyls increases susceptibility to neuronal stress at a mature age.

Journal: Neurotoxicology 20160301

Title: Detection and measurement of the agonistic activities of PCBs and mono-hydroxylated PCBs to the constitutive androstane receptor using a recombinant yeast assay.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20151001

Title: Polychlorinated Biphenyls (PCB 101, 153, and 180) Impair Murine Macrophage Responsiveness to Lipopolysaccharide: Involvement of NF-κB Pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150901

Title: Exploring the associations between microRNA expression profiles and environmental pollutants in human placenta from the National Children's Study (NCS).

Journal: Epigenetics 20150801

Title: Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways.

Journal: Toxicology letters 20150402

Title: Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.

Journal: Toxicology and applied pharmacology 20150401

Title: Lactational exposure to low levels of the six indicator non-dioxin-like polychlorinated biphenyls induces DNA damage and repression of neuronal activity, in juvenile male mice.

Journal: Toxicology 20150203

Title: Polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) alter leptin signaling and lipid metabolism in differentiated 3T3-L1 adipocytes.

Journal: Toxicology and applied pharmacology 20140915

Title: Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes.

Journal: Toxicology and applied pharmacology 20131001

Title: Comparative study on 2,2',4,5,5'-pentachlorobiphenyl-mediated decrease in serum thyroxine level between C57BL/6 and its transthyretin-deficient mice.

Journal: Toxicology and applied pharmacology 20120915

Title: Neurodevelopmental and behavioral toxicity via lactational exposure to the sum of six indicator non-dioxin-like-polychlorinated biphenyls (∑6 NDL-PCBs) in mice.

Journal: Toxicology 20120904

Title: Biological monitoring of indoor-exposure to dioxin-like and non-dioxin-like polychlorinated biphenyls (PCB) in a public building.

Journal: Toxicology letters 20120813

Title: Long-term trends of continental-scale PCB patterns studied using a global atmosphere-ocean general circulation model.

Journal: Environmental science and pollution research international 20120701

Title: Effects of polychlorinated biphenyls in CD-1 mice: reproductive toxicity and intergenerational transmission.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120301

Title: Biodegradation of PCB congeners by white rot fungus, Ceriporia sp. ZLY-2010, and analysis of metabolites.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101

Title: A non-invasive approach to study lifetime exposure and bioaccumulation of PCBs in protected marine mammals: PBPK modeling in harbor porpoises.

Journal: Toxicology and applied pharmacology 20111015

Title: Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs.

Journal: Toxicology letters 20111010

Title: Genotoxic effects of polychlorinated biphenyls (PCB 153, 138, 101, 118) in a fish cell line (RTG-2).

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110801

Title: Organochlorine pesticide and polychlorinated biphenyls levels in fish and mussel in Van region, Turkey.

Journal: Bulletin of environmental contamination and toxicology 20110701

Title: In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110501

Title: Effects of non-dioxin-like polychlorinated biphenyl congeners (PCB 101, PCB 153 and PCB 180) alone or mixed on J774A.1 macrophage cell line: modification of apoptotic pathway.

Journal: Toxicology letters 20110410

Title: Fluorescence detection of trace PCB101 based on PITC immobilized on porous AAO membrane.

Journal: The Analyst 20110121

Title: Non-dioxin-like PCBs interact with benzo[a]pyrene-induced p53-responses and inhibit apoptosis.

Journal: Toxicology and applied pharmacology 20101201

Title: Evaluation of an hPXR reporter gene assay for the detection of aquatic emerging pollutants: screening of chemicals and application to water samples.

Journal: Analytical and bioanalytical chemistry 20100101

Title: Determination of lead, cadmium, and persistent organic pollutants in wild and orchard-farm-grown fruit in northeastern Poland.

Journal: Journal of toxicology and environmental health. Part A 20100101

Title: Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells.

Journal: Chemico-biological interactions 20091210

Title: Degradation of pentachlorobiphenyl by a sequential treatment using Pd coated iron and an aerobic bacterium (H1).

Journal: Chemosphere 20090901

Title: Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants.

Journal: Environmental science & technology 20090815

Title: Cell death mechanisms in GT1-7 GnRH cells exposed to polychlorinated biphenyls PCB74, PCB118, and PCB153.

Journal: Toxicology and applied pharmacology 20090601

Title: Catalytic dechlorination of polychlorinated biphenyls in soil by palladium-iron bimetallic catalyst.

Journal: Journal of hazardous materials 20090515

Title: Destruction of pentachlorobiphenyl in soil by supercritical CO(2) extraction coupled with polymer-stabilized palladium nanoparticles.

Journal: Chemosphere 20090501

Title: An Assessment of Mutagenic Effect of 3, 3', 4, 4', 5 Pentachlorobiphenyl (PCB126) in Muta Mouse Fetuses.

Journal: The Journal of veterinary medical science 20090401

Title: Pesticide contamination profiles of water, sediment and aquatic organisms in the effluent of Gaobeidian wastewater treatment plant.

Journal: Chemosphere 20080701

Title: Different effects of PCB101, PCB118, PCB138 and PCB153 alone or mixed in MCF-7 breast cancer cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080701

Title: Serum concentrations of indicator PCB congeners in the Czech adult population.

Journal: Chemosphere 20080701

Title: Relationship of thyroid hormone levels to levels of polychlorinated biphenyls, lead, p,p'- DDE, and other toxicants in Akwesasne Mohawk youth.

Journal: Environmental health perspectives 20080601

Title: Immune cell counts and risks of respiratory infections among infants exposed pre- and postnatally to organochlorine compounds: a prospective study.

Journal: Environmental health : a global access science source 20080101

Title: Associations between prenatal exposure to polychlorinated biphenyls and neonatal thyroid-stimulating hormone levels in a Mexican-American population, Salinas Valley, California.

Journal: Environmental health perspectives 20071001

Title: Improved quality control in gas chromatography interfaced to stable isotope ratio mass spectrometry by application of derivative chromatography.

Journal: Analytica chimica acta 20070502

Title: [Metabolism of 2,2',4,5,5'-pentachlorobiphenyl (CB101) by liver microsomes of rats, hamsters and guinea pigs].

Journal: Fukuoka igaku zasshi = Hukuoka acta medica 20070501

Title: Optimization of separation and detection conditions for comprehensive two-dimensional gas chromatography--time-of-flight mass spectrometry analysis of polychlorinated dibenzo-p-dioxins and dibenzofurans.

Journal: Journal of chromatography. A 20070323

Title: Bioaccumulation of 14C-PCB 101 and 14C-PBDE 99 in the marine planktonic copepod Calanus finmarchicus under different food regimes.

Journal: Marine environmental research 20070201

Title: Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls.

Journal: European journal of clinical pharmacology 20061201

Title: Tumor promoting potency of PCBs 28 and 101 in rat liver.

Journal: Toxicology letters 20060701

Title: Specific human CYP 450 isoform metabolism of a pentachlorobiphenyl (PCB-IUPAC# 101).

Journal: Biochemical and biophysical research communications 20060526

Title: Effects of PCBs and MeSO2-PCBs on adrenocortical steroidogenesis in H295R human adrenocortical carcinoma cells.

Journal: Chemosphere 20060501

Title: Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1).

Journal: Chemical research in toxicology 20060101

Title: Apoptosis in bovine cumulus-oocyte complexes after exposure to polychlorinated biphenyl mixtures during in vitro maturation.

Journal: Reproduction (Cambridge, England) 20051201

Title: The decrease in level of serum thyroxine by 2,2',4,5,5'-pentachlorobiphenyl in rats and mice: no correlation with formation of methylsulfonyl metabolites.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101

Title: Species differences in the tissue distribution of catechol and methylsulphonyl metabolites of 2,4,5,2',5'-penta- and 2,3,4,2',3',6'-hexachlorobiphenyls in rats, mice, hamsters and guinea pigs.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050101

Title: Lineage-specific effects of polychlorinated biphenyls (PCB) on gene expression in the rabbit blastocyst.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20050101

Title: Metabolism of polychlorinated biphenyls by Gunn rats: identification and serum retention of catechol metabolites.

Journal: Chemical research in toxicology 20041201

Title: A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041001

Title: Retention indexes for temperature-programmed gas chromatography of polychlorinated biphenyls.

Journal: Analytical chemistry 20040915

Title: An unrecognized source of PCB contamination in schools and other buildings.

Journal: Environmental health perspectives 20040701

Title: Tumor promoters as inhibitors of apoptosis in rat hepatocytes.

Journal: Toxicology letters 20040401

Title: Ortho-substituted polychlorinated biphenyl (PCB) congeners (95 or 101) decrease pituitary response to thyrotropin releasing hormone.

Journal: Toxicology letters 20030930

Title: Proliferative effects of estradiol, progesterone, and two CB congeners and their metabolites on gray seal (Halichoerus grypus) uterine myocytes in vitro.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030901

Title: Metabolic disturbances in fish exposed to sodium pentachlorophenate (NaPCP) and 3,3',4,4',5-pentachlorobiphenyl (PCB126), individually or combined.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020801

Title: The hypothalamo-pituitary-thyroid (HPT) axis: a target of nonpersistent ortho-substituted PCB congeners.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020101

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SDS
Tags:37680-73-2 Molecular Formula|37680-73-2 MDL|37680-73-2 SMILES|37680-73-2 1,1'-Biphenyl, 2,2',4,5,5'-pentachloro- |Organic_Building_Blocks