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38083-17-9,MFCD00055505
Catalog No.:AA0034JM

38083-17-9 | 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5g
98%
in stock  
$24.00   $17.00
- +
25g
≥98%
in stock  
$63.00   $44.00
- +
50g
≥98%
in stock  
$112.00   $78.00
- +
100g
98%
in stock  
$170.00   $119.00
- +
250g
≥98%
in stock  
$398.00   $278.00
- +
500g
98%
in stock  
$517.00   $362.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0034JM
Chemical Name:
1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
CAS Number:
38083-17-9
Molecular Formula:
C15H17ClN2O2
Molecular Weight:
292.7607
MDL Number:
MFCD00055505
SMILES:
Clc1ccc(cc1)OC(C(=O)C(C)(C)C)n1cncc1
NSC Number:
759808
Properties
Properties
 
Form:
Solid  
MP:
96-100°C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
335  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.7  

Literature

Title: Efficacy of a piroctone olamine/climbazol shampoo in comparison with a zinc pyrithione shampoo in subjects with moderate to severe dandruff.

Journal: International journal of cosmetic science 20110601

Title: Evaluation of the genotoxicity of the imidazole antifungal climbazole: comparison to published results for other azole compounds.

Journal: Mutation research 20090101

Title: [Determination of antidangdruff agent salicylic acid, zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo by high performance liquid chromatography].

Journal: Wei sheng yan jiu = Journal of hygiene research 20050901

Title: Induction and inhibition of cytochrome P450 and drug-metabolizing enzymes by climbazole.

Journal: Biological & pharmaceutical bulletin 20020101

Title: [Clinical effectiveness and tolerance of climbazole containing dandruff shampoo in patients with seborrheic scalp eczema].

Journal: Praxis 20010816

Title: Climbazole is a new potent inducer of rat hepatic cytochrome P450.

Journal: The Journal of toxicological sciences 20010801

Title: Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25;8(1):8161.

Title: Y Kobayashi, et al. Climbazole is a new potent inducer of rat hepatic cytochrome P450. J Toxicol Sci. 2001 Aug;26(3):141-50.

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Tags:38083-17-9 Molecular Formula|38083-17-9 MDL|38083-17-9 SMILES|38083-17-9 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one |Heterocyclic_Building_Blocks