Title: Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals.
Journal: Chemical research in toxicology 20170515
Title: High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities.
Journal: Archives of toxicology 20170101
Title: New use for an old drug: COX-independent anti-inflammatory effects of sulindac in models of cystic fibrosis.
Journal: British journal of pharmacology 20160601
Title: Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10.
Journal: Chemico-biological interactions 20150605
Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Journal: Chemical research in toxicology 20150518
Title: Sulindac, 3,3'-diindolylmethane and curcumin reduce carcinogenesis in the Pirc rat, an Apc-driven model of colon carcinogenesis.
Journal: BMC cancer 20150101
Title: A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101
Title: Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101
Title: Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking.
Journal: Journal of molecular modeling 20121201
Title: Entrapment of human flavin-containing monooxygenase 3 in the presence of gold nanoparticles: TEM, FTIR and electrocatalysis.
Journal: Biochimica et biophysica acta 20121201
Title: Serum biomarker modulation following molecular targeting of epidermal growth factor and cyclooxygenase pathways: a pilot randomized trial in head and neck cancer.
Journal: Oral oncology 20121101
Title: Beneficial effects of sulindac in focal cerebral ischemia: a positive role in Wnt/β-catenin pathway.
Journal: Brain research 20121030
Title: Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas.
Journal: Cancer causes & control : CCC 20121001
Title: COX inhibitors Indomethacin and Sulindac derivatives as antiproliferative agents: synthesis, biological evaluation, and mechanism investigation.
Journal: European journal of medicinal chemistry 20121001
Title: Nitric oxide donor exisulind is an effective inhibitor of murine photocarcinogenesis.
Journal: Photochemistry and photobiology 20120901
Title: Regioselective oxidation of phospho-NSAIDs by human cytochrome P450 and flavin monooxygenase isoforms: implications for their pharmacokinetic properties and safety.
Journal: British journal of pharmacology 20120901
Title: A prospective, controlled phase II study of neoadjuvant exisulind therapy before radical prostatectomy: effect on apoptosis.
Journal: Urology 20120801
Title: Citalopram alleviates chronic stress induced depression-like behaviors in rats by activating GSK3β signaling in dorsal hippocampus.
Journal: Brain research 20120727
Title: Role of Sulindac and Celecoxib in the regulation of angiogenesis during the early neoplasm of colon: exploring PI3-K/PTEN/Akt pathway to the canonical Wnt/β-catenin signaling.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120701
Title: Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Journal: European journal of medicinal chemistry 20120701
Title: The HMGA1-COX-2 axis: a key molecular pathway and potential target in pancreatic adenocarcinoma.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20120701
Title: Assessment of the involvement of oxidative stress and Mitogen-Activated Protein Kinase signaling pathways in the cytotoxic effects of arsenic trioxide and its combination with sulindac or its metabolites: sulindac sulfide and sulindac sulfone on human leukemic cell lines.
Journal: Medical oncology (Northwood, London, England) 20120601
Title: Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis.
Journal: Oncology reports 20120601
Title: A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.
Journal: Cancer prevention research (Philadelphia, Pa.) 20120601
Title: First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms.
Journal: The Journal of biological chemistry 20120406
Title: The metabolism and pharmacokinetics of phospho-sulindac (OXT-328) and the effect of difluoromethylornithine.
Journal: British journal of pharmacology 20120401
Title: Synergistic cytotoxic effect of sulindac and pyrrolidine dithiocarbamate against ovarian cancer cells.
Journal: Oncology reports 20120401
Title: Target delivery and controlled release of the chemopreventive drug sulindac by using an advanced layered double hydroxide nanomatrix formulation system.
Journal: Journal of materials science. Materials in medicine 20120401
Title: Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect.
Journal: Biochemical pharmacology 20120315
Title: Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.
Journal: Journal of medicinal chemistry 20120308
Title: Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120301
Title: Role of Sulindac and Celecoxib in chemoprevention of colorectal cancer via intrinsic pathway of apoptosis: exploring NHE-1, intracellular calcium homeostasis and Calpain 9.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120301
Title: In vitro drug metabolism by C-terminally truncated human flavin-containing monooxygenase 3.
Journal: Biochemical pharmacology 20120215
Title: The novel compound OSI-461 induces apoptosis and growth arrest in human acute myeloid leukemia cells.
Journal: Annals of hematology 20120201
Title: Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.
Journal: The Journal of pharmacology and experimental therapeutics 20120201
Title: Muscle relaxants for pain management in rheumatoid arthritis.
Journal: The Cochrane database of systematic reviews 20120118
Title: DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines.
Journal: International journal of cancer 20120115
Title: The molecular basis for inhibition of sulindac and its metabolites towards human aldose reductase.
Journal: FEBS letters 20120102
Title: Facilitation of human osteoblast apoptosis by sulindac and indomethacin under hypoxic injury.
Journal: Journal of cellular biochemistry 20120101
Title: Drug-induced chronic pancreatitis.
Journal: Medicine and health, Rhode Island 20120101
Title: Modulation of apoptosis protein profiles--role of P-gp in HeLa cells exposed to doxorubicin.
Journal: Cancer genomics & proteomics 20120101
Title: Colorectal cancer chemoprevention: is this the future of colorectal cancer prevention?
Journal: TheScientificWorldJournal 20120101
Title: Combination of sulindac and dichloroacetate kills cancer cells via oxidative damage.
Journal: PloS one 20120101
Title: Jaded smiles: ancient Mayan dental inlays and today's Central American patients.
Journal: Journal of the Massachusetts Dental Society 20120101
Title: Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
Journal: PloS one 20120101
Title: Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury.
Journal: Toxicology 20111218
Title: Chemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds.
Journal: Cancer research 20111215
Title: An old NSAID revisited: crystal structure of aldose reductase in complex with sulindac at 1.0 Å supports a novel mechanism for its anticancer and antiproliferative effects.
Journal: ChemMedChem 20111209
Title: Non steroidal anti-inflammatory drugs modulate the physicochemical properties of plasma membrane in experimental colorectal cancer: a fluorescence spectroscopic study.
Journal: Molecular and cellular biochemistry 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein.
Journal: The Journal of biological chemistry 20111118
Title: An intermittent approach for cancer chemoprevention.
Journal: Nature reviews. Cancer 20111110
Title: Functional characterization of peroxisome proliferator-activated receptor-β/δ expression in colon cancer.
Journal: Molecular carcinogenesis 20111101
Title: Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).
Journal: Prostaglandins & other lipid mediators 20111101
Title: Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats.
Journal: Cancer prevention research (Philadelphia, Pa.) 20111101
Title: Novel human mPGES-1 inhibitors identified through structure-based virtual screening.
Journal: Bioorganic & medicinal chemistry 20111015
Title: The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway.
Journal: Apoptosis : an international journal on programmed cell death 20110901
Title: FOXO3 is inhibited by oncogenic PI3K/Akt signaling but can be reactivated by the NSAID sulindac sulfide.
Journal: The Journal of clinical endocrinology and metabolism 20110901
Title: A sulindac analogue is effective against malignant pleural effusion in mice.
Journal: Lung cancer (Amsterdam, Netherlands) 20110801
Title: Inhibition of PDE5 by sulindac sulfide selectively induces apoptosis and attenuates oncogenic Wnt/β-catenin-mediated transcription in human breast tumor cells.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110801
Title: Sulindac and its metabolites: sulindac sulfide and sulindac sulfone enhance cytotoxic effects of arsenic trioxide on leukemic cell lines.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110801
Title: Manufacture and performance evaluation of a stable amorphous complex of an acidic drug molecule and Neusilin.
Journal: Journal of pharmaceutical sciences 20110801
Title: Phospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110701
Title: Studies on the metabolism and biological activity of the epimers of sulindac.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110601
Title: Randomized double-blind trial of sulindac and etodolac to eradicate aberrant crypt foci and to prevent sporadic colorectal polyps.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110601
Title: Sulindac sulfide induces autophagic death in gastric epithelial cells via survivin down-regulation: a mechanism of NSAIDs-induced gastric injury.
Journal: Biochemical pharmacology 20110601
Title: Of timing and surrogates: a way forward for cancer chemoprevention.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110601
Title: Effects of intervention with sulindac and inulin/VSL#3 on mucosal and luminal factors in the pouch of patients with familial adenomatous polyposis.
Journal: International journal of colorectal disease 20110501
Title: Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.
Journal: Journal of medicinal chemistry 20110414
Title: The novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats.
Journal: British journal of pharmacology 20110401
Title: Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities.
Journal: Journal of pharmaceutical and biomedical analysis 20110325
Title: The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon.
Journal: Gut 20110301
Title: [Antitumor effects of sulindac in ovarian cell cultures].
Journal: Ginekologia polska 20110301
Title: A phase I study of OSI-461 in combination with mitoxantrone in patients with advanced solid tumors potentially responsive to mitoxantrone.
Journal: Cancer chemotherapy and pharmacology 20110201
Title: Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110201
Title: TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells.
Journal: The Journal of pathology 20110201
Title: Randomized phase II trial of sulindac, atorvastatin, and prebiotic dietary fiber for colorectal cancer chemoprevention.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110201
Title: Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies.
Journal: Bioorganic & medicinal chemistry 20110201
Title: Role of nonsteroidal anti-inflammatory drug-activated gene-1 in docetaxel-induced cell death of human colorectal cancer cells with different p53 status.
Journal: Archives of pharmacal research 20110201
Title: Intervening in β-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis.
Journal: Neoplasia (New York, N.Y.) 20110201
Title: Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101
Title: The role of NAG-1/GDF15 in the inhibition of intestinal polyps in APC/Min mice by sulindac.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110101
Title: Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARα and PLZF/RARα.
Journal: PloS one 20110101
Title: Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.
Journal: PloS one 20110101
Title: Effect of sulindac sulfide on metallohydrolases in the human colon cancer cell line HT-29.
Journal: PloS one 20110101
Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20101116
Title: Phospho-sulindac (OXT-922) inhibits the growth of human colon cancer cell lines: a redox/polyamine-dependent effect.
Journal: Carcinogenesis 20101101
Title: Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells.
Journal: European journal of medicinal chemistry 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Ornithine decarboxylase-1 polymorphism, chemoprevention with eflornithine and sulindac, and outcomes among colorectal adenoma patients.
Journal: Journal of the National Cancer Institute 20101006
Title: Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice.
Journal: Gastroenterology 20101001
Title: Fluo-cAMP is transported by multidrug resistance-associated protein isoform 4 in rat choroid plexus.
Journal: Journal of neurochemistry 20101001
Title: Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition.
Journal: Cancer prevention research (Philadelphia, Pa.) 20101001
Title: Suppression of growth arrest and DNA damage-inducible 45alpha expression confers resistance to sulindac and indomethacin-induced gastric mucosal injury.
Journal: The Journal of pharmacology and experimental therapeutics 20100901
Title: Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma.
Journal: Gastroenterology 20100901
Title: Molecular alterations associated with sulindac-resistant colon tumors in ApcMin/+ mice.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100901
Title: Sulindac and its metabolites inhibit multiple transport proteins in rat and human hepatocytes.
Journal: The Journal of pharmacology and experimental therapeutics 20100801
Title: Induction of p53-independent apoptosis by a novel synthetic hexahydrocannabinol analog is mediated via Sp1-dependent NSAID-activated gene-1 in colon cancer cells.
Journal: Biochemical pharmacology 20100701
Title: A novel sulindac derivative lacking cyclooxygenase-inhibitory activities suppresses carcinogenesis in the transgenic adenocarcinoma of mouse prostate model.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100701
Title: Oxidative stress is important in the pathogenesis of liver injury induced by sulindac and lipopolysaccharide cotreatment.
Journal: Toxicology 20100604
Title: R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100601
Title: Sulindac reverses aberrant expression and localization of beta-catenin in papillary thyroid cancer cells with the BRAFV600E mutation.
Journal: Thyroid : official journal of the American Thyroid Association 20100601
Title: Radiological reasoning: multiple mesenteric masses.
Journal: AJR. American journal of roentgenology 20100601
Title: Loss of GDF-15 abolishes sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer.
Journal: Journal of cancer research and clinical oncology 20100401
Title: The integrated stress response-associated signals modulates intestinal tumor cell growth by NSAID-activated gene 1 (NAG-1/MIC-1/PTGF-beta).
Journal: Carcinogenesis 20100401
Title: Sulindac metabolites induce proteosomal and lysosomal degradation of the epidermal growth factor receptor.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100401
Title: Curcumin potentiates the pro-apoptotic effects of sulindac sulfone in colorectal cancer.
Journal: Expert opinion on investigational drugs 20100401
Title: Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori.
Journal: Dalton transactions (Cambridge, England : 2003) 20100321
Title: Sulindac sulfide suppresses 5-lipoxygenase at clinically relevant concentrations.
Journal: Cellular and molecular life sciences : CMLS 20100301
Title: Sulindac sulfone induces a decrease of beta-catenin in HNSCC.
Journal: Anticancer research 20100201
Title: Synergistic action of doxorubicin and sulindac in human cervix carcinoma cells - studies on possible mechanisms.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20100101
Title: Sulindac and sulindac metabolites in nipple aspirate fluid and effect on drug targets in a phase I trial.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100101
Title: Possible role of HSP60 in synergistic action of anthracyclines and sulindac in HeLa cells.
Journal: Acta poloniae pharmaceutica 20100101
Title: The cyclooxygenase inhibitor sulindac sulfide inhibits EP4 expression and suppresses the growth of glioblastoma cells.
Journal: Cancer prevention research (Philadelphia, Pa.) 20091201
Title: Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G.
Journal: Molecular cancer therapeutics 20091201
Title: Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention.
Journal: Essays in biochemistry 20091104
Title: Sulindac prevents carcinogen-induced intrahepatic cholangiocarcinoma formation in vivo.
Journal: The Journal of surgical research 20091101
Title: Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations.
Journal: Carcinogenesis 20091101
Title: Up-regulation of GADD45alpha expression by NSAIDs leads to apoptotic and necrotic colon cancer cell deaths.
Journal: Apoptosis : an international journal on programmed cell death 20091101
Title: Chemical and structural biology to direct the repurposing of sulindac.
Journal: ChemMedChem 20091101
Title: Flushing out the diagnosis.
Journal: Journal of hospital medicine 20091101
Title: Combination of sulindac and antimicrobial eradication of Helicobacter pylori prevents progression of gastric cancer in hypergastrinemic INS-GAS mice.
Journal: Cancer research 20091015
Title: Sulindac metabolism and synergy with tumor necrosis factor-alpha in a drug-inflammation interaction model of idiosyncratic liver injury.
Journal: The Journal of pharmacology and experimental therapeutics 20091001
Title: Nutrition and colon cancer prevention.
Journal: Current opinion in clinical nutrition and metabolic care 20090901
Title: Sulindac induces apoptotic cell death in susceptible human breast cancer cells through, at least in part, inhibition of IKKbeta.
Journal: Apoptosis : an international journal on programmed cell death 20090701
Title: The influence of double bond geometry in the inhibition of cyclooxygenases by sulindac derivatives.
Journal: Bioorganic & medicinal chemistry letters 20090615
Title: Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells.
Journal: European journal of pharmacology 20090610
Title: The oncogenic effects of constitutive Stat3 signaling in salivary gland cancer cells are mediated by survivin and modulated by the NSAID sulindac.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20090601
Title: Lung tumor promotion by curcumin.
Journal: Carcinogenesis 20090601
Title: A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.
Journal: Cancer prevention research (Philadelphia, Pa.) 20090601
Title: Synthesis, pharmacological evaluation and docking studies of new sulindac analogues.
Journal: European journal of medicinal chemistry 20090501
Title: [Role of peroxisome proliferators-activated receptor-gamma in the chemical prevention therapy of sulindac for precancerous lesions of rats].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20090418
Title: Inhibitory effect of sulindac on DMBA-induced hamster cheek pouch carcinogenesis and its derived cell line.
Journal: Oncology reports 20090401
Title: Off-label use of approved drugs.
Journal: Nature reviews. Clinical oncology 20090401
Title: Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs.
Journal: Chemico-biological interactions 20090316
Title: Novel dithiolethione-modified nonsteroidal anti-inflammatory drugs in human hepatoma HepG2 and colon LS180 cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090315
Title: Hepatotoxic interaction of sulindac with lipopolysaccharide: role of the hemostatic system.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090301
Title: Risk of cardiovascular events in a randomized placebo-controlled, double-blind trial of difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas.
Journal: Cancer prevention research (Philadelphia, Pa.) 20090301
Title: A dose-ranging study of the pharmacokinetics and pharmacodynamics of the selective apoptotic antineoplastic drug (SAAND), OSI-461, in patients with advanced cancer, in the fasted and fed state.
Journal: Cancer chemotherapy and pharmacology 20090201
Title: A phase II study of carboplatin, etoposide, and exisulind in patients with extensive small cell lung cancer: CALGB 30104.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20090201
Title: Reducing the risk of recurrent colon polyps.
Journal: Clinical advances in hematology & oncology : H&O 20090201
Title: NO-sulindac inhibits the hypoxia response of PC-3 prostate cancer cells via the Akt signalling pathway.
Journal: International journal of cancer 20090101
Title: Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death.
Journal: Carcinogenesis 20090101
Title: Topical sulindac combined with hydrogen peroxide in the treatment of actinic keratoses.
Journal: Journal of drugs in dermatology : JDD 20090101
Title: Inhibitory effects of 5-fluorouracil and oxaliplatin on human colorectal cancer cell survival are synergistically enhanced by sulindac sulfide.
Journal: Anticancer research 20090101
Title: Sulindac enhances the killing of cancer cells exposed to oxidative stress.
Journal: PloS one 20090101
Title: Suppressive effect of sulindac on branch duct-intraductal papillary mucinous neoplasms.
Journal: Journal of gastroenterology 20090101
Title: Sulindac inhibits canonical Wnt signaling by blocking the PDZ domain of the protein Dishevelled.
Journal: Angewandte Chemie (International ed. in English) 20090101
Title: Single dose oral sulindac for acute postoperative pain in adults.
Journal: The Cochrane database of systematic reviews 20090101
Title: Longitudinal assessment of air conduction audiograms in a phase III clinical trial of difluoromethylornithine and sulindac for prevention of sporadic colorectal adenomas.
Journal: Cancer prevention research (Philadelphia, Pa.) 20081201
Title: The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents.
Journal: Cancer research 20081015
Title: Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Journal: Journal of medicinal chemistry 20081009
Title: A combination of sulindac and arsenic trioxide synergistically induces apoptosis in human lung cancer H1299 cells via c-Jun NH2-terminal kinase-dependent Bcl-xL phosphorylation.
Journal: Lung cancer (Amsterdam, Netherlands) 20080901
Title: Cellular imaging predictions of clinical drug-induced liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080901
Title: Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention.
Journal: International journal of cancer 20080901
Title: Phase I/II study of vinorelbine and exisulind as first-line treatment of advanced non-small cell lung cancer in patients at least 70 years old: a wisconsin oncology network study.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080901
Title: A phase II study of estramustine, docetaxel, and exisulind in patients with hormone- refractory prostate cancer: results of cancer and leukemia group B trial 90004.
Journal: Clinical genitourinary cancer 20080901
Title: Sulindac derivatives that activate the peroxisome proliferator-activated receptor gamma but lack cyclooxygenase inhibition.
Journal: Journal of medicinal chemistry 20080828
Title: Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases.
Journal: Oncology reports 20080801
Title: Sulindac treatment alters collagen and matrilysin expression in adenomas of ApcMin/+ mice.
Journal: Carcinogenesis 20080701
Title: Sulindac enhances arsenic trioxide-mediated apoptosis by inhibition of NF-kappaB in HCT116 colon cancer cells.
Journal: Oncology reports 20080701
Title: Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase.
Journal: Molecular cancer therapeutics 20080701
Title: Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts.
Journal: Molecular cancer therapeutics 20080701
Title: Interactions of sulindac and its metabolites with phospholipid membranes: an explanation for the peroxidation protective effect of the bioactive metabolite.
Journal: Free radical research 20080701
Title: Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment.
Journal: International journal of pharmaceutics 20080624
Title: Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase.
Journal: The Journal of biological chemistry 20080620
Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Journal: Journal of medicinal chemistry 20080612
Title: Drugs to prevent colon cancer show promise, but hurdles remain for chemoprevention.
Journal: Journal of the National Cancer Institute 20080604
Title: Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial.
Journal: Cancer prevention research (Philadelphia, Pa.) 20080601
Title: Clinical prevention of recurrence of colorectal adenomas by the combination of difluoromethylornithine and sulindac: an important milestone.
Journal: Cancer prevention research (Philadelphia, Pa.) 20080601
Title: Effects of sulindac sulfide on the membrane architecture and the activity of gamma-secretase.
Journal: Neuropharmacology 20080501
Title: The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB.
Journal: Oncogene 20080417
Title: Interactions of acetylcholinesterase with caveolin-1 and subsequently with cytochrome c are required for apoptosome formation.
Journal: Carcinogenesis 20080401
Title: Sulindac suppresses beta-catenin expression in human cancer cells.
Journal: European journal of pharmacology 20080331
Title: Qualitative and quantitative characterization of the amyloid beta peptide (Abeta) population in biological matrices using an immunoprecipitation-LC/MS assay.
Journal: Journal of neuroscience methods 20080315
Title: Growth compensatory role of sulindac sulfide-induced thrombospondin-1 linked with ERK1/2 and RhoA GTPase signaling pathways.
Journal: Life sciences 20080312
Title: Sulindac and its metabolites induce carcinogen metabolizing enzymes in human colon cancer cells.
Journal: International journal of cancer 20080301
Title: Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB.
Journal: Molecular pharmacology 20080301
Title: Combined effects of sulindac and suberoylanilide hydroxamic acid on apoptosis induction in human lung cancer cells.
Journal: Molecular pharmacology 20080301
Title: Comparative bioavailability of sulindac in capsule and tablet formulations.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080301
Title: Aseptic meningitis associated with chronic sulindac use for osteoarthritis: a case report.
Journal: Rheumatology international 20080201
Title: Chemoprevention with special reference to inherited colorectal cancer.
Journal: Familial cancer 20080101
Title: Unique MAP Kinase binding sites.
Journal: Biochimica et biophysica acta 20080101
Title: Chemoprevention of arylamine-induced colorectal aberrant crypts.
Journal: Experimental biology and medicine (Maywood, N.J.) 20080101
Title: SMAC mimetics sensitize nonsteroidal anti-inflammatory drug-induced apoptosis by promoting caspase-3-mediated cytochrome c release.
Journal: Cancer research 20080101
Title: Relevance of the concept of oncogene addiction to hormonal carcinogenesis and molecular targeting in cancer prevention and therapy.
Journal: Advances in experimental medicine and biology 20080101
Title: Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation.
Journal: Journal of neuroinflammation 20080101
Title: Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis.
Journal: Nutrition and cancer 20080101
Title: The management of desmoids in patients with familial adenomatous polyposis (FAP).
Journal: Acta chirurgica Iugoslavica 20080101
Title: Sulindac prevents esophageal adenocarcinomas induced by gastroduodenal reflux in rats.
Journal: Yonsei medical journal 20071231
Title: Signal peptide peptidase and gamma-secretase share equivalent inhibitor binding pharmacology.
Journal: The Journal of biological chemistry 20071221
Title: Anti-angiogenic properties of a sulindac analogue.
Journal: British journal of pharmacology 20071201
Title: New form discovery for the analgesics flurbiprofen and sulindac facilitated by polymer-induced heteronucleation.
Journal: Journal of pharmaceutical sciences 20071101
Title: Use of sulindac in polyhydramnios.
Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20071101
Title: Relative non-steroidal anti-inflammatory drug (NSAID) antiproliferative activity is mediated through p21-induced G1 arrest and E2F inhibition.
Journal: Molecular carcinogenesis 20071001
Title: Exisulind in combination with celecoxib modulates epidermal growth factor receptor, cyclooxygenase-2, and cyclin D1 against prostate carcinogenesis: in vivo evidence.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071001
Title: Docetaxel and exisulind in previously treated non-small cell lung cancer (NSCLC) patients: a multicenter, phase II clinical trial.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20071001
Title: Up-regulation of early growth response gene 1 (EGR-1) via ERK1/2 signals attenuates sulindac sulfide-mediated cytotoxicity in the human intestinal epithelial cells.
Journal: Toxicology and applied pharmacology 20070901
Title: The effect of long-term treatment with sulindac on the progression of diabetic retinopathy.
Journal: Current medical research and opinion 20070801
Title: A case of Cronkhite-Canada syndrome with colorectal adenomas: effect of the nonsteroidal anti-inflammatory drug sulindac.
Journal: The American journal of gastroenterology 20070801
Title: Desmethyl derivatives of indomethacin and sulindac as probes for cyclooxygenase-dependent biology.
Journal: ACS chemical biology 20070720
Title: Survivin is a downstream target and effector of sulindac-sensitive oncogenic Stat3 signalling in head and neck cancer.
Journal: International journal of oral and maxillofacial surgery 20070701
Title: Spontaneous regression of rectal polyps following abdominal colectomy and ileorectal anastomosis for familial adenomatous polyposis, without sulindac treatment: report of four cases.
Journal: Endoscopy 20070701
Title: Sulindac loaded alginate beads for a mucoprotective and controlled drug release.
Journal: Journal of microencapsulation 20070601
Title: Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo.
Journal: Molecular cancer therapeutics 20070601
Title: Functionalized magnetic nanoparticles for small-molecule isolation, identification, and quantification.
Journal: Analytical chemistry 20070501
Title: Sulindac sulfone modulates beta-catenin in human cholesteatoma cell culture.
Journal: Archives of medical research 20070501
Title: Sulindac treatment in hereditary non-polyposis colorectal cancer.
Journal: European journal of cancer (Oxford, England : 1990) 20070501
Title: Defective acute apoptotic response to genotoxic carcinogen in small intestine of APC(Min/+) mice is restored by sulindac.
Journal: Cancer letters 20070418
Title: JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo.
Journal: European journal of pharmacology 20070410
Title: Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells.
Journal: Histology and histopathology 20070401
Title: One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia--a new paradigm.
Journal: Transfusion 20070401
Title: Nonsteroidal anti-inflammatory drugs induce colorectal cancer cell apoptosis by suppressing 14-3-3epsilon.
Journal: Cancer research 20070401
Title: Non-steroidal anti-inflammatory agents, tolmetin and sulindac attenuate quinolinic acid (QA)-induced oxidative stress in primary hippocampal neurons and reduce QA-induced spatial reference memory deficits in male Wistar rats.
Journal: Life sciences 20070320
Title: The same gamma-secretase accounts for the multiple intramembrane cleavages of APP.
Journal: Journal of neurochemistry 20070301
Title: Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinoma.
Journal: Neoplasia (New York, N.Y.) 20070301
Title: [Effect of peroxisome proliferators-activated receptor-gamma in the mechanisms of sulindac against large intestine carcinoma].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20070218
Title: Alpha-tocopheryl succinate sensitizes human colon cancer cells to exisulind-induced apoptosis.
Journal: Apoptosis : an international journal on programmed cell death 20070201
Title: A 10-year review of surgery for desmoid disease associated with familial adenomatous polyposis (Br J Surg 2006; 93; 1258-1264).
Journal: The British journal of surgery 20070201
Title: Polyproline-rod approach to isolating protein targets of bioactive small molecules: isolation of a new target of indomethacin.
Journal: Journal of the American Chemical Society 20070131
Title: Sulindac induces specific degradation of the HPV oncoprotein E7 and causes growth arrest and apoptosis in cervical carcinoma cells.
Journal: Cancer letters 20070108
Title: A phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer.
Journal: Cancer chemotherapy and pharmacology 20070101
Title: Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction.
Journal: Apoptosis : an international journal on programmed cell death 20070101
Title: Effects of non-steroidal anti-inflammatory drugs on blood pressure.
Journal: Journal of hypertension 20070101
Title: Differential activity of sulindac metabolites against squamous cell carcinoma of the head and neck is mediated by p21waf1/cip1 induction and cell cycle inhibition.
Journal: Cancer biology & therapy 20070101
Title: Immunomodulatory effect of nonsteroidal anti-inflammatory drugs (NSAIDs) at the clinically available doses.
Journal: Archives of pharmacal research 20070101
Title: Dietary anthocyanin-rich tart cherry extract inhibits intestinal tumorigenesis in APC(Min) mice fed suboptimal levels of sulindac.
Journal: Journal of agricultural and food chemistry 20061213
Title: Effects of oral dosing paradigms (gavage versus diet) on pharmacokinetics and pharmacodynamics.
Journal: Chemico-biological interactions 20061201
Title: Sulindac, a nonsteroidal anti-inflammatory drug, selectively inhibits interferon-gamma-induced expression of the chemokine CXCL9 gene in mouse macrophages.
Journal: Biochemical and biophysical research communications 20061117
Title: Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin.
Journal: Biochemical pharmacology 20061115
Title: Non-steroidal anti-inflammatory agents, tolmetin and sulindac, inhibit liver tryptophan 2,3-dioxygenase activity and alter brain neurotransmitter levels.
Journal: Life sciences 20061110
Title: Exisulind induces apoptosis in advanced myelodysplastic syndrome (MDS) and acute myeloid leukaemia/MDS.
Journal: British journal of haematology 20061101
Title: p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis.
Journal: Oncology reports 20061101
Title: Intra- or intercomplex binding to the gamma-secretase enzyme. A model to differentiate inhibitor classes.
Journal: The Journal of biological chemistry 20061020
Title: 15-Hydroxyprostaglandin-dehydrogenase is involved in anti-proliferative effect of non-steroidal anti-inflammatory drugs COX-1 inhibitors on a human medullary thyroid carcinoma cell line.
Journal: Prostaglandins & other lipid mediators 20061001
Title: High perinatal survival in monoamniotic twins managed by prophylactic sulindac, intensive ultrasound surveillance, and Cesarean delivery at 32 weeks' gestation.
Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 20061001
Title: Mitochondrial uncoupling by the sulindac metabolite, sulindac sulfide.
Journal: Basic & clinical pharmacology & toxicology 20061001
Title: Inhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agents.
Journal: Current drug metabolism 20061001
Title: Non-steroidal anti-inflammatory agents, tolmetin and sulindac, attenuate oxidative stress in rat brain homogenate and reduce quinolinic acid-induced neurodegeneration in rat hippocampal neurons.
Journal: Metabolic brain disease 20060901
Title: A phase II trial of carboplatin and gemcitabine with exisulind (IND #65,056) in patients with advanced non-small cell lung cancer: an Eastern Cooperative Oncology Group study (E1501).
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060901
Title: Sulindac regulates the aryl hydrocarbon receptor-mediated expression of Phase 1 metabolic enzymes in vivo and in vitro.
Journal: Carcinogenesis 20060801
Title: Chemopreventive alteration of the cell-cell adhesion in head and neck squamous cell cancer.
Journal: Oncology reports 20060801
Title: Non-steroidal anti-inflammatory drug-related hepatic damage in France and Spain: analysis from national spontaneous reporting systems.
Journal: Fundamental & clinical pharmacology 20060801
Title: Phase II evaluation of docetaxel plus exisulind in patients with androgen independent prostate carcinoma.
Journal: American journal of clinical oncology 20060801
Title: Hepatic disorders in patients treated with COX-2 selective inhibitors or nonselective NSAIDs: a case/noncase analysis of spontaneous reports.
Journal: Clinical therapeutics 20060801
Title: Proapoptotic activity of NAG-1 is cell type specific and not related to COX-2 expression.
Journal: Apoptosis : an international journal on programmed cell death 20060701
Title: [Inhibition of gastric cancer cells growth in vitro by sulindac].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20060701
Title: Capillary electrophoresis combining field-amplified sample stacking and electroosmotic flow suppressant for analysis of sulindac and its two metabolites in plasma.
Journal: Journal of chromatography. A 20060630
Title: Combination treatment with arsenic trioxide and sulindac augments their apoptotic potential in lung cancer cells through activation of caspase cascade and mitochondrial dysfunction.
Journal: International journal of oncology 20060601
Title: Differential targeting of protein kinase B in cell death induced by sulindac and its metabolite sulindac sulfide.
Journal: International journal of oncology 20060601
Title: Sulindac sulfide and exisulind inhibit expression of the estrogen and progesterone receptors in human breast cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060601
Title: Apoptosis: a relevant tool for anticancer therapy.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20060601
Title: Cyclooxygenase-2 expression in hamster and human pancreatic neoplasia.
Journal: Neoplasia (New York, N.Y.) 20060601
Title: Inhibition of chemically induced skin carcinogenesis by sulindac is independent of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).
Journal: Carcinogenesis 20060501
Title: Novel drug release profiles from micellar solutions of PLA-PEO-PLA triblock copolymers.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Nonsteroidal antiinflammatory drugs during third trimester and the risk of premature closure of the ductus arteriosus: a meta-analysis.
Journal: The Annals of pharmacotherapy 20060501
Title: Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.
Journal: Molecular cancer therapeutics 20060501
Title: Early loss of Fhit in the respiratory tract of rodents exposed to environmental cigarette smoke.
Journal: Cancer research 20060401
Title: Id-1 gene downregulation by sulindac sulfide and its upregulation during tumor development in gastric cancer.
Journal: International journal of cancer 20060315
Title: Sporadic adenomatous polyp regression with exisulind is effective but toxic: a randomised, double blind, placebo controlled, dose-response study.
Journal: Gut 20060301
Title: Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways.
Journal: Molecular cancer therapeutics 20060301
Title: Phase I/II study of gemcitabine and exisulind as second-line therapy in patients with advanced non-small cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060301
Title: Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells.
Journal: The Biochemical journal 20060215
Title: Inhibitory effects of black tea theaflavin derivatives on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears.
Journal: Molecular nutrition & food research 20060201
Title: [Non-steroidal anti-inflammatory agents and prevention of colorectal adenomas and carcinomas].
Journal: Ugeskrift for laeger 20060123
Title: MF tricyclic and sulindac retard tumor formation in an animal model.
Journal: International journal of cancer 20060101
Title: Phase I clinical trial of weekly docetaxel and exisulind, a novel inducer of apoptosis.
Journal: Investigational new drugs 20060101
Title: The sulindac derivatives OSI-461, OSIP486823, and OSIP487703 arrest colon cancer cells in mitosis by causing microtubule depolymerization.
Journal: Molecular cancer therapeutics 20060101
Title: Effect of the non-steroidal anti-inflammatory drug sulindac on colorectal adenomas of uncolectomized familial adenomatous polyposis.
Journal: Journal of gastroenterology and hepatology 20060101
Title: Antiangiogenic effect of sulindac sulfide could be secondary to induction of apoptosis and cell cycle arrest.
Journal: Anticancer research 20060101
Title: Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer.
Journal: PloS one 20060101
Title: COX-independent antineoplastic effects of sulindac in oral cancer are mediated by survivin down-regulation.
Journal: Anticancer research 20060101
Title: Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis.
Journal: Nutrition and cancer 20060101
Title: Modulation of multigene expression and proteome profiles by chemopreventive agents.
Journal: Mutation research 20051211
Title: Modulation of apoptosis by cancer chemopreventive agents.
Journal: Mutation research 20051211
Title: Both PPARgamma and PPARdelta influence sulindac sulfide-mediated p21WAF1/CIP1 upregulation in a human prostate epithelial cell line.
Journal: Oncogene 20051208
Title: Sulindac suppresses nuclear factor-kappaB activation and RANTES gene and protein expression in endometrial stromal cells from women with endometriosis.
Journal: The Journal of clinical endocrinology and metabolism 20051201
Title: Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries determine vessel plasticity.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051201
Title: Differential gene expression of sulindac-treated human breast epithelial cells.
Journal: International journal of oncology 20051201
Title: Exisulind in the treatment of prostate cancer.
Journal: Expert review of anticancer therapy 20051201
Title: Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene.
Journal: The Journal of pharmacology and experimental therapeutics 20051101
Title: Sulindac sulfone is most effective in modulating beta-catenin-mediated transcription in cells with mutant APC.
Journal: Annals of the New York Academy of Sciences 20051101
Title: p27kip1 in intestinal tumorigenesis and chemoprevention in the mouse.
Journal: Cancer research 20051015
Title: Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice.
Journal: International journal of cancer 20051010
Title: Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenografts in immunodeficient mice.
Journal: The Journal of pharmacology and experimental therapeutics 20051001
Title: Genetic polymorphisms of flavin monooxygenase 3 in sulindac-induced regression of colorectal adenomas in familial adenomatous polyposis.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20051001
Title: Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2.
Journal: Molecular cancer therapeutics 20051001
Title: Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1.
Journal: Molecular cancer therapeutics 20051001
Title: Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.
Journal: Cancer research 20050915
Title: Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells.
Journal: Life sciences 20050902
Title: [The effects of sulindac on the pathology of colorectal remnant polyps of familial adenomatous polyposis (FAP) patients].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20050818
Title: Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling.
Journal: The Journal of biological chemistry 20050805
Title: The influence of sulindac on diabetic cardiomyopathy: a non-invasive evaluation by Doppler echocardiography in streptozotocin-induced diabetic rats.
Journal: Vascular pharmacology 20050801
Title: Sulindac enhances the proteasome inhibitor bortezomib-mediated oxidative stress and anticancer activity.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050715
Title: Glucuronidation of nonsteroidal anti-inflammatory drugs: identifying the enzymes responsible in human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701
Title: Sulindac inhibits beta-catenin expression in normal-appearing colon of hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis patients.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050701
Title: [Possibilities in the treatment of primary biliary cirrhosis].
Journal: Orvosi hetilap 20050605
Title: Inhibition of IKK down-regulates antigen + IgE-induced TNF production by mast cells: a role for the IKK-IkappaB-NF-kappaB pathway in IgE-dependent mast cell activation.
Journal: Journal of leukocyte biology 20050601
Title: The nonsteroidal anti-inflammatory drug Exisulind selectively induces apoptosis via JNK in secondary acute myeloid leukemia after myelodysplastic syndrome.
Journal: Cell cycle (Georgetown, Tex.) 20050601
Title: Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: implication in apoptosis resistance.
Journal: Experimental cell research 20050515
Title: Sulindac induces apoptosis and protects against colon carcinoma in mice.
Journal: World journal of gastroenterology 20050514
Title: Random mutagenesis of presenilin-1 identifies novel mutants exclusively generating long amyloid beta-peptides.
Journal: The Journal of biological chemistry 20050513
Title: A phase I/II dose-escalation study of exisulind and docetaxel in patients with hormone-refractory prostate cancer.
Journal: BJU international 20050501
Title: The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3).
Journal: Molecular cancer therapeutics 20050501
Title: A phase I/II study of exisulind in combination with docetaxel/carboplatin in patients with metastatic non-small-cell lung cancer.
Journal: Clinical lung cancer 20050501
Title: Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Journal: Journal of medicinal chemistry 20050407
Title: Uncoupling of oxidative phosphorylation and Smac/DIABLO release are not sufficient to account for induction of apoptosis by sulindac sulfide in human colorectal cancer cells.
Journal: International journal of oncology 20050401
Title: Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis.
Journal: Journal of neurochemistry 20050401
Title: Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells.
Journal: Molecular cancer therapeutics 20050401
Title: Apoptosis of human gastric cancer SGC-7901 cells induced by mitomycin combined with sulindac.
Journal: World journal of gastroenterology 20050328
Title: Methylation in the p21WAF1/cip1 promoter of Apc+/-, p21+/- mice and lack of response to sulindac.
Journal: Oncogene 20050317
Title: Inhibition of angiogenesis-relevant receptor tyrosine kinases by sulindac analogues.
Journal: Chembiochem : a European journal of chemical biology 20050301
Title: Tocolytic therapy and clinical experience. Combination therapy.
Journal: BJOG : an international journal of obstetrics and gynaecology 20050301
Title: The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15.
Journal: Molecular cancer therapeutics 20050301
Title: Mechanisms of sulindac-induced apoptosis and cell cycle arrest.
Journal: Cancer letters 20050227
Title: Sulindac and its metabolites inhibit invasion of glioblastoma cells via down-regulation of Akt/PKB and MMP-2.
Journal: Journal of cellular biochemistry 20050215
Title: Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer.
Journal: Molecular cancer therapeutics 20050201
Title: Sulindac sulfide-induced apoptosis in sinonasal cancer cells.
Journal: Acta oto-laryngologica 20050201
Title: The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells.
Journal: Experimental cell research 20050115
Title: Lack of specific amyloid-beta(1-42) suppression by nonsteroidal anti-inflammatory drugs in young, plaque-free Tg2576 mice and in guinea pig neuronal cultures.
Journal: The Journal of pharmacology and experimental therapeutics 20050101
Title: Nonsteroidal antiinflammatory drugs differentially suppress endometriosis in a murine model.
Journal: Fertility and sterility 20050101
Title: Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells.
Journal: Molecular cancer therapeutics 20050101
Title: Induction and modulation of lung tumors: genomic and transcriptional alterations in cigarette smoke-exposed mice.
Journal: Experimental lung research 20050101
Title: [Non-steroid anti-inflammatory drugs in the treatment of Alzheimer's disease].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101
Title: Genetic polymorphisms of human flavin monooxygenase 3 in sulindac-mediated primary chemoprevention of familial adenomatous polyposis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041215
Title: Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation.
Journal: Oncogene 20041209
Title: Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.
Journal: Journal of the National Cancer Institute 20041201
Title: Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites.
Journal: Cancer research 20041115
Title: Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041115
Title: A phase I and pharmacokinetic study of exisulind and docetaxel in patients with advanced solid tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041101
Title: Selected non-steroidal anti-inflammatory drugs and their derivatives target gamma-secretase at a novel site. Evidence for an allosteric mechanism.
Journal: The Journal of biological chemistry 20041015
Title: Non-steroidal anti-inflammatory drug activated gene (NAG-1) expression is closely related to death receptor-4 and -5 induction, which may explain sulindac sulfide induced gastric cancer cell apoptosis.
Journal: Carcinogenesis 20041001
Title: Alterations of gene expression in skin and lung of mice exposed to light and cigarette smoke.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041001
Title: Nitrosulindac (NCX 1102): a new nitric oxide-donating non-steroidal anti-inflammatory drug (NO-NSAID), inhibits proliferation and induces apoptosis in human prostatic epithelial cell lines.
Journal: The Prostate 20041001
Title: Modulation of the transactivation function of nuclear factor-kappaB by lipopolysaccharide in RAW264.7 macrophages.
Journal: International journal of oncology 20041001
Title: Suppression of angiogenic activity of sera from diabetic patients with non-proliferative retinopathy by compounds of herbal origin and sulindac sulfone.
Journal: International journal of molecular medicine 20041001
Title: Synergistic effects of acyclic retinoid and OSI-461 on growth inhibition and gene expression in human hepatoma cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041001
Title: Ursodeoxycholate/Sulindac combination treatment effectively prevents intestinal adenomas in a mouse model of polyposis.
Journal: Gastroenterology 20040901
Title: Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression.
Journal: The Journal of biological chemistry 20040827
Title: Purification and characterization of the human gamma-secretase complex.
Journal: Biochemistry 20040803
Title: Cough and angioedema from angiotensin-converting enzyme inhibitors: new insights into mechanisms and management.
Journal: Current opinion in allergy and clinical immunology 20040801
Title: High-dose tamoxifen and sulindac as first-line treatment for desmoid tumors.
Journal: Cancer 20040801
Title: Glutathione-S-transferase P1-1 protects aberrant crypt foci from apoptosis induced by deoxycholic acid.
Journal: Gastroenterology 20040801
Title: Nutritional-pharmacological combinations--a novel approach to reducing colon cancer incidence.
Journal: European journal of nutrition 20040801
Title: Comparison of the anti-proliferation and apoptosis-induction activities of sulindac, celecoxib, curcumin, and nifedipine in mismatch repair-deficient cell lines.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20040801
Title: Chemoprevention of carcinogenesis in familial tumors.
Journal: International journal of clinical oncology 20040801
Title: Induction of transcription by p21Waf1/Cip1/Sdi1: role of NFkappaB and effect of non-steroidal anti-inflammatory drugs.
Journal: Cell cycle (Georgetown, Tex.) 20040701
Title: Anti-cancer effects of COX-2 inhibitors and their correlation with angiogenesis and invasion in gastric cancer.
Journal: World journal of gastroenterology 20040701
Title: Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells.
Journal: Cancer research 20040601
Title: Replication of the Weber effect using postmarketing adverse event reports voluntarily submitted to the United States Food and Drug Administration.
Journal: Pharmacotherapy 20040601
Title: OSI-461 (OSI).
Journal: Current opinion in investigational drugs (London, England : 2000) 20040601
Title: Combined effect of arsenic trioxide and sulindac sulfide in A549 human lung cancer cells in vitro.
Journal: Journal of experimental & clinical cancer research : CR 20040601
Title: COX-2 inhibition and colorectal cancer.
Journal: Seminars in oncology 20040401
Title: -to: Gardiner TA, Anderson HR, Degenhardt T et al. (2003) prevention of retinal capillary basement membrane thickening in diabetic dogs by a non-steroidal anti-inflammatory drug. Diabetologia 46:1269-1275.
Journal: Diabetologia 20040401
Title: Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice.
Journal: Toxicology and applied pharmacology 20040315
Title: Sulindac sulfide and caffeic acid phenethyl ester suppress the motility of lung adenocarcinoma cells promoted by transforming growth factor-beta through Akt inhibition.
Journal: Journal of cancer research and clinical oncology 20040301
Title: Drug-induced liver injury.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040301
Title: Antiproliferative effect of nitrosulindac (NCX 1102), a new nitric oxide-donating non-steroidal anti-inflammatory drug, on human bladder carcinoma cell lines.
Journal: Molecular cancer therapeutics 20040301
Title: Sulindac improves memory and increases NMDA receptor subunits in aged Fischer 344 rats.
Journal: Neurobiology of aging 20040301
Title: The chemopreventive agent sulindac attenuates expression of the antiapoptotic protein survivin in colorectal carcinoma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20040201
Title: High-dose tamoxifen and sulindac as first-line treatment for desmoid tumors.
Journal: Cancer 20040201
Title: Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis.
Journal: Gastroenterology 20040201
Title: Adenomas of the ampulla of vater in familial adenomatous polyposis: Christian Theodore responds.
Journal: Gastroenterology 20040201
Title: Identification of potent Ras signaling inhibitors by pathway-selective phenotype-based screening.
Journal: Angewandte Chemie (International ed. in English) 20040116
Title: Sulindac-derived Ras pathway inhibitors target the Ras-Raf interaction and downstream effectors in the Ras pathway.
Journal: Angewandte Chemie (International ed. in English) 20040116
Title: Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines.
Journal: British journal of cancer 20040112
Title: Differential effects of selective COX-2 inhibitors on cell cycle regulation and proliferation of glioblastoma cell lines.
Journal: Cancer biology & therapy 20040101
Title: Increased anti-tumour efficacy of doxorubicin when combined with sulindac in a xenograft model of an MRP-1-positive human lung cancer.
Journal: Anticancer research 20040101
Title: Exisulind: Aptosyn, FGN 1, Prevatac, sulindac sulfone.
Journal: Drugs in R&D 20040101
Title: Combinatorial chemoprevention: efficacy of lovostatin and exisulind on the formation and progression of aberrant crypt foci.
Journal: Anticancer research 20040101
Title: Reduction of Sulindac to its active metabolite, sulindac sulfide: assay and role of the methionine sulfoxide reductase system.
Journal: Biochemical and biophysical research communications 20031226
Title: Nonsteroidal anti-inflammatory drugs inhibit growth of human neuroendocrine tumor cells via G1 cell-cycle arrest.
Journal: International journal of cancer 20031210
Title: Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells.
Journal: Apoptosis : an international journal on programmed cell death 20031201
Title: Combination of tumor necrosis factor-alpha with sulindac in human carcinoma cells in vivo.
Journal: Annals of the New York Academy of Sciences 20031201
Title: Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer.
Journal: The Journal of biological chemistry 20031128
Title: Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho.
Journal: Science (New York, N.Y.) 20031114
Title: Hepatocellular damage from non-steroidal anti-inflammatory drugs.
Journal: QJM : monthly journal of the Association of Physicians 20031101
Title: The metabolism of sulindac enhances its scavenging activity against reactive oxygen and nitrogen species.
Journal: Free radical biology & medicine 20031101
Title: MEK inhibition of pancreatic carcinoma cells by U0126 and its effect in combination with sulindac.
Journal: Pancreas 20031101
Title: [Management of duodenal adenomatosis in patients with familial adenomatous polyposis].
Journal: Annales de chirurgie 20031101
Title: Exisulind and related compounds inhibit expression and function of the androgen receptor in human prostate cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20031015
Title: Prostaglandin inhibitors in preterm labour.
Journal: Best practice & research. Clinical obstetrics & gynaecology 20031001
Title: [Pioglitazone, a peroxisome proliferators-activated receptor gamma ligand, inhibits dimethylhydrazine (DMH) induced aberrant crypt foci in rats].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20031001
Title: Phase I and II study of exisulind in combination with capecitabine in patients with metastatic breast cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030915
Title: Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells.
Journal: The Biochemical journal 20030901
Title: Systemic genotoxic effects produced by light, and synergism with cigarette smoke in the respiratory tract of hairless mice.
Journal: Carcinogenesis 20030901
Title: Prevention of retinal capillary basement membrane thickening in diabetic dogs by a non-steroidal anti-inflammatory drug.
Journal: Diabetologia 20030901
Title: Apoptosis induction and enhancement of cytotoxicity of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines.
Journal: International journal of oncology 20030901
Title: Okadaic acid induces sustained activation of NFkappaB and degradation of the nuclear IkappaBalpha in human neutrophils.
Journal: Archives of biochemistry and biophysics 20030901
Title: Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells.
Journal: Molecular cancer therapeutics 20030901
Title: Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity.
Journal: The Journal of biological chemistry 20030822
Title: Rofecoxib (Vioxx), a specific cyclooxygenase-2 inhibitor, is chemopreventive in a mouse model of colon cancer.
Journal: American journal of clinical oncology 20030801
Title: Gene modulation by the cyclooxygenase inhibitor, sulindac sulfide, in human colorectal carcinoma cells: possible link to apoptosis.
Journal: The Journal of biological chemistry 20030711
Title: Cyclo-oxygenase 2 inhibitors: emerging roles in the gut.
Journal: International journal of colorectal disease 20030701
Title: ROCK and nuclear factor-kappaB-dependent activation of cyclooxygenase-2 by Rho GTPases: effects on tumor growth and therapeutic consequences.
Journal: Molecular biology of the cell 20030701
Title: Expression of apoptosis regulators in cutaneous T-cell lymphoma (CTCL) cells.
Journal: The Journal of pathology 20030601
Title: Lactacystin augments the sulindac-induced apoptosis in HT-29 cells.
Journal: Apoptosis : an international journal on programmed cell death 20030601
Title: Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation.
Journal: The Journal of biological chemistry 20030516
Title: Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival.
Journal: Molecular cancer therapeutics 20030501
Title: Chemoprevention of colorectal cancer: slow, steady progress.
Journal: Cleveland Clinic journal of medicine 20030401
Title: A double-blind randomized study of fetal side effects during and after the short-term maternal administration of indomethacin, sulindac, and nimesulide for the treatment of preterm labor.
Journal: American journal of obstetrics and gynecology 20030401
Title: Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle.
Journal: The Journal of pharmacy and pharmacology 20030401
Title: [Inhibition of vascular smooth muscle cell proliferation by non-steroidal anti-inflammatory drugs].
Journal: Shi yan sheng wu xue bao 20030401
Title: Combination of tumor necrosis factor-alpha with sulindac augments its apoptotic potential and suppresses tumor growth of human carcinoma cells in nude mice.
Journal: Cancer 20030315
Title: Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations.
Journal: Carcinogenesis 20030301
Title: Chemoprevention for colorectal tumorigenesis associated with chronic colitis in mice via apoptosis.
Journal: Journal of experimental & clinical cancer research : CR 20030301
Title: Cardiovascular and renal effects of cyclooxygenase inhibition in transgenic rats harboring mouse renin-2 gene (TGR[mREN2]27).
Journal: European journal of pharmacology 20030214
Title: Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells.
Journal: Cancer research 20030201
Title: Anti-angiogenic and apoptotic effects of metabolites of sulindac on chick embryo chorioallantoic membrane.
Journal: Hybridoma and hybridomics 20030201
Title: The combined treatment of aspirin and radiation induces apoptosis by the regulation of bcl-2 and caspase-3 in human cervical cancer cell.
Journal: Cancer letters 20030128
Title: What's new in the treatment of advanced prostate cancer?
Journal: European journal of cancer (Oxford, England : 1990) 20030101
Title: Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac.
Journal: Carcinogenesis 20030101
Title: Thermodynamic characterization of the binding process of sulindac to human serum albumin.
Journal: Arzneimittel-Forschung 20030101
Title: New TNF-alpha releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen.
Journal: Mutation research 20030101
Title: Inhibition of the phosphatidylinositol 3'-kinase signaling pathway increases the responsiveness of pancreatic carcinoma cells to sulindac.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20030101
Title: Molecular basis of sulindac competition with specific markers for the major binding sites on human serum albumin.
Journal: Arzneimittel-Forschung 20030101
Title: Exisulind and CP248 induce growth inhibition and apoptosis in human esophageal adenocarcinoma and squamous carcinoma cells.
Journal: Journal of experimental therapeutics & oncology 20030101
Title: The influence of sulindac on patients with primary biliary cirrhosis that responds incompletely to ursodeoxycholic acid: a pilot study.
Journal: European journal of gastroenterology & hepatology 20021201
Title: Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model.
Journal: Carcinogenesis 20021201
Title: No effect of cyclooxygenase inhibition on plaque size in atherosclerosis-prone mice.
Journal: Scandinavian cardiovascular journal : SCJ 20021201
Title: Modulation by colony stimulating factors of human epithelial colon cancer cell apoptosis.
Journal: Cytokine 20021124
Title: Chemoprevention of FAP with sulindac.
Journal: Current oncology reports 20021101
Title: Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs.
Journal: The Journal of pharmacology and experimental therapeutics 20021101
Title: Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation.
Journal: Biochemical pharmacology 20021101
Title: Rapid development of colitis in NSAID-treated IL-10-deficient mice.
Journal: Gastroenterology 20021101
Title: Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention.
Journal: Cancer research 20021101
Title: Effects of long-term administration of sulindac on APC mRNA and apoptosis in colons of rats treated with azoxymethane.
Journal: Journal of cancer research and clinical oncology 20021101
Title: Discovery of molecular mechanisms of neuroprotection using cell-based bioassays and oligonucleotide arrays.
Journal: Physiological genomics 20021029
Title: Benzylamide sulindac analogues induce changes in cell shape, loss of microtubules and G(2)-M arrest in a chronic lymphocytic leukemia (CLL) cell line and apoptosis in primary CLL cells.
Journal: Cancer research 20021015
Title: Phase I and pharmacokinetic trial of the proapoptotic sulindac analog CP-461 in patients with advanced cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20021001
Title: Effect of sulindac treatment for attenuated familial adenomatous polyposis with a new germline APC mutation at codon 161: report of a case.
Journal: Diseases of the colon and rectum 20021001
Title: Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Journal: Mutation research 20020930
Title: A mouse model of human oral-esophageal cancer.
Journal: The Journal of clinical investigation 20020915
Title: Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells.
Journal: Oncogene 20020905
Title: Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents.
Journal: Carcinogenesis 20020901
Title: [Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma].
Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20020901
Title: Sulindac in familial adenomatous polyposis.
Journal: The New England journal of medicine 20020822
Title: [Rectal carcinoma in a patient with familial adenomatous polyposis coli after colectomy with ileorectal anastomosis and consecutive chemoprevention with sulindac suppositories].
Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20020801
Title: Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G.
Journal: Molecular cancer therapeutics 20020801
Title: Rectal epithelial apoptosis does not predict response to sulindac treatment or polyp development in presymptomatic familial adenomatous polyposis patients.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020701
Title: Primary chemoprevention of familial adenomatous polyposis with sulindac: more questions than answers.
Journal: Gastroenterology 20020701
Title: Sulindac derivative-induced apoptosis in a human umbilical vein endothelial cell line ECV304.
Journal: Chinese medical journal 20020701
Title: Novel clinical trials in androgen-independent prostate cancer.
Journal: Clinical prostate cancer 20020601
Title: Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue.
Journal: Gastroenterology 20020501
Title: PPARgamma-mediated antineoplastic effect of NSAID sulindac on human oral squamous carcinoma cells.
Journal: International journal of cancer 20020420
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: Primary chemoprevention of familial adenomatous polyposis with sulindac.
Journal: The New England journal of medicine 20020404
Title: Cyclooxygenase inhibition in cancer--a blind alley or a new therapeutic reality?
Journal: The New England journal of medicine 20020404
Title: Chemoprevention of esophageal adenocarcinoma by COX-2 inhibitors in an animal model of Barrett's esophagus.
Journal: Gastroenterology 20020401
Title: CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells.
Journal: Molecular cancer therapeutics 20020401
Title: Expression profile analysis of colon cancer cells in response to sulindac or aspirin.
Journal: Biochemical and biophysical research communications 20020329
Title: Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
Journal: Cancer research 20020315
Title: The new sulindac derivative IND 12 reverses Ras-induced cell transformation.
Journal: Cancer research 20020315
Title: Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane.
Journal: Cancer letters 20020308
Title: Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study.
Journal: Gastroenterology 20020301
Title: Exisulind in combination with docetaxel inhibits growth and metastasis of human lung cancer and prolongs survival in athymic nude rats with orthotopic lung tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020301
Title: Induction of apoptosis by sulindac in azoxymethane-induced possible colonic premalignant lesions in rats.
Journal: Japanese journal of cancer research : Gann 20020301
Title: Observation on the therapeutic effect of Shu Feng Huo Luo Pian for treatment of osseous arthritis.
Journal: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20020301
Title: New indene-derivatives with anti-proliferative properties.
Journal: Bioorganic & medicinal chemistry letters 20020225
Title: The nonsteroidal anti-inflammatory drug sulindac causes down-regulation of signal transducer and activator of transcription 3 in human oral squamous cell carcinoma cells.
Journal: Cancer research 20020215
Title: GATA-6 transcriptional regulation of 15-lipoxygenase-1 during NSAID-induced apoptosis in colorectal cancer cells.
Journal: Cancer research 20020215
Title: Induction of multidrug resistance proteins MRP1 and MRP3 and gamma-glutamylcysteine synthetase gene expression by nonsteroidal anti-inflammatory drugs in human colon cancer cells.
Journal: Biochemical and biophysical research communications 20020208
Title: Sulindac enhances tumor necrosis factor-alpha-mediated apoptosis of lung cancer cell lines by inhibition of nuclear factor-kappaB.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020201
Title: Preclinical and clinical studies of docetaxel and exisulind in the treatment of human lung cancer.
Journal: Seminars in oncology 20020201
Title: [Experimental study on sulindac metabolites -induced apoptosis on human umbilical vein endothelial cell line ECV304].
Journal: Zhonghua fu chan ke za zhi 20020201
Title: [Chemoprevention of colorectal cancer].
Journal: Presse medicale (Paris, France : 1983) 20020126
Title: Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice.
Journal: Cancer research 20020115
Title: Inhibition of cell transformation by sulindac sulfide is confined to specific oncogenic pathways.
Journal: Cancer letters 20020110
Title: Prevention and chemoprevention of colorectal neoplasms.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20020101
Title: Resistance to apoptosis is increased during metastatic dissemination of colon cancer.
Journal: Clinical & experimental metastasis 20020101
Title: Sulindac induces apoptosis, inhibits proliferation and activates caspase-3 in Hep G2 cells.
Journal: Anticancer research 20020101
Title: Effects of betamethasone, sulindac and quinacrine drugs on the inflammatory neoangiogenesis response induced by polyurethane sponge implanted in mouse.
Journal: Biological research 20020101
Title: [The growth inhibition of colorectal adenoma cells by sulindac and its mechanisms].
Journal: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20020101
Title: beta-Catenin signaling: therapeutic strategies in oncology.
Journal: Cancer biology & therapy 20020101
Title: Protein phosphatase 2A interacts with and directly dephosphorylates RelA.
Journal: The Journal of biological chemistry 20011221
Title: Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro.
Journal: Genes & development 20011215
Title: Growth inhibition and apoptosis induction of Sulindac on Human gastric cancer cells.
Journal: World journal of gastroenterology 20011215
Title: Progression and NSAID-induced apoptosis in malignant melanomas are independent of cyclooxygenase II.
Journal: Melanoma research 20011201
Title: Molecular analysis of sulindac-resistant adenomas in familial adenomatous polyposis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011201
Title: Chemopreventive agents inhibit aberrant proliferation of the aneuploid phenotype in a colon epithelial cell line established from Apc 1638N [+/-] mouse.
Journal: Annals of the New York Academy of Sciences 20011201
Title: Nerve pathology in the type 1 diabetic dog: effects of treatment with sulindac.
Journal: Journal of the peripheral nervous system : JPNS 20011201
Title: Sulindac inhibited gene expression and activity of arylamine N-acetyltransferase and DNA-2-aminofluorene adduct formation in T24 human bladder tumor cells.
Journal: Urological research 20011201
Title: A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.
Journal: Nature 20011108
Title: Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells.
Journal: The Journal of pharmacology and experimental therapeutics 20011101
Title: Complete regression of colonic adenomas after treatment with sulindac in Gardner's syndrome: a 4-year follow-up.
Journal: Journal of gastroenterology 20011101
Title: A Fas-associated death domain protein-dependent mechanism mediates the apoptotic action of non-steroidal anti-inflammatory drugs in the human leukemic Jurkat cell line.
Journal: The Journal of biological chemistry 20011019
Title: Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase.
Journal: Cancer research 20011015
Title: Sulindac to prevent recurrent preterm labor: a randomized controlled trial.
Journal: Obstetrics and gynecology 20011001
Title: Exisulind, a selective apoptotic antineoplastic drug.
Journal: Expert opinion on investigational drugs 20011001
Title: Effects of non-steroidal anti-inflammatory drugs on hypertension control using angiotensin converting enzyme inhibitors and thiazide diuretics.
Journal: East African medical journal 20011001
Title: Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis.
Journal: Oncogene 20010927
Title: Sulindac sulfide-induced apoptosis involves death receptor 5 and the caspase 8-dependent pathway in human colon and prostate cancer cells.
Journal: Cancer research 20010915
Title: Safety and efficacy of exisulind for treatment of recurrent prostate cancer after radical prostatectomy.
Journal: The Journal of urology 20010901
Title: Cell cycle effects of nonsteroidal anti-inflammatory drugs and enhanced growth inhibition in combination with gemcitabine in pancreatic carcinoma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20010901
Title: Cancer prevention with green tea and monitoring by a new biomarker, hnRNP B1.
Journal: Mutation research 20010901
Title: Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29.
Journal: Experimental cell research 20010815
Title: Suppression of intestinal polyps in Msh2-deficient and non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor.
Journal: Cancer research 20010815
Title: p21(WAF1/cip1) is an important determinant of intestinal cell response to sulindac in vitro and in vivo.
Journal: Cancer research 20010815
Title: Relationship between APC genotype, polyp distribution, and oral sulindac treatment in the colon and rectum of patients with familial adenomatous polyposis.
Journal: Diseases of the colon and rectum 20010801
Title: Docetaxel and exisulind in hormone-refractory prostate cancer.
Journal: Seminars in oncology 20010801
Title: Sulindac-associated choledocholithiasis.
Journal: The American journal of gastroenterology 20010701
Title: Enhanced apoptosis and transforming growth factor-beta1 expression in colorectal adenomas and carcinomas after Sulindac therapy.
Journal: Diseases of the colon and rectum 20010701
Title: Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells.
Journal: International journal of cancer 20010615
Title: Antiproliferative effects of nitrosulindac on human colon adenocarcinoma cell lines.
Journal: Biochemical and biophysical research communications 20010615
Title: Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression.
Journal: Cancer research 20010615
Title: Rat colorectal tumours treated with a range of non-steroidal anti-inflammatory drugs show altered cyclooxygenase-2 and cyclooxygenase-1 splice variant mRNA expression levels.
Journal: Carcinogenesis 20010601
Title: Prolonged activation of mitogen-activated protein kinases during NSAID-induced apoptosis in HT-29 colon cancer cells.
Journal: International journal of colorectal disease 20010601
Title: Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis.
Journal: Cancer research 20010515
Title: Regulation of renal proximal tubular epithelial cell hyaluronan generation: implications for diabetic nephropathy.
Journal: Kidney international 20010501
Title: Sulindac in familial adenomatous polyposis: evaluation by nuclear morphometry.
Journal: The European journal of surgery = Acta chirurgica 20010501
Title: Sulindac and its derivatives: a novel class of anticancer agents.
Journal: Current opinion in investigational drugs (London, England : 2000) 20010501
Title: Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention.
Journal: Cancer research 20010415
Title: Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cells.
Journal: Biochemical and biophysical research communications 20010406
Title: Proapoptotic anti-inflammatory drugs.
Journal: Urology 20010401
Title: Restoration of epithelial cell polarity in a colorectal cancer cell line by suppression of beta-catenin/T-cell factor 4-mediated gene transactivation.
Journal: Cancer research 20010315
Title: Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites.
Journal: Cancer research 20010215
Title: Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor.
Journal: Cancer research 20010215
Title: Bowen's disease (squamous cell carcinoma in situ) in immunosuppressed patients treated with imiquimod 5% cream and a cox inhibitor, sulindac: potential applications for this combination of immunotherapy.
Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20010201
Title: Antiproliferative effects of S-allylmercaptocysteine on colon cancer cells when tested alone or in combination with sulindac sulfide.
Journal: Cancer research 20010115
Title: Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors.
Journal: Carcinogenesis 20010101
Title: Combination cancer chemoprevention with green tea extract and sulindac shown in intestinal tumor formation in Min mice.
Journal: Journal of cancer research and clinical oncology 20010101
Title: Directed control of electroosmotic flow in nonaqueous electrolytes using poly(ethylene glycol) coated capillaries.
Journal: Electrophoresis 20010101
Title: Cyclooxygenase inhibitors are potent sensitizers of prostate tumours to hyperthermia and radiation.
Journal: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20010101
Title: Induction of apoptosis by sulindac sulfide in HL60 cells is enhanced by p21CiP1 or p27KiP1.
Journal: Anticancer research 20010101
Title: Growth-suppressive effect of non-steroidal anti-inflammatory drugs on 11 colon-cancer cell lines and fluorescence differential display of genes whose expression is influenced by sulindac.
Journal: International journal of cancer 20001215
Title: Sulindac and a cyclooxygenase-2 inhibitor, etodolac, increase APC mRNA in the colon of rats treated with azoxymethane.
Journal: Gut 20001201
Title: Sulindac sulfone inhibits K-ras-dependent cyclooxygenase-2 expression in human colon cancer cells.
Journal: Cancer research 20001201
Title: Non-steroidal anti-inflammatory drugs with different cyclooxygenase inhibitory profiles that prevent aberrant crypt foci formation but vary in acute gastrotoxicity in a rat model.
Journal: Journal of gastroenterology and hepatology 20001201
Title: Role of BAX in the apoptotic response to anticancer agents.
Journal: Science (New York, N.Y.) 20001103
Title: Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20001001
Title: Two opposing effects of non-steroidal anti-inflammatory drugs on the expression of the inducible cyclooxygenase. Mediation through different signaling pathways.
Journal: The Journal of biological chemistry 20000908
Title: [A case of rheumatoid arthritis associated with autoimmune hemolytic anemia due to weekly low-dose methotrexate therapy].
Journal: Ryumachi. [Rheumatism] 20000801
Title: 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells.
Journal: Journal of the National Cancer Institute 20000719
Title: Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta).
Journal: Molecular and cellular biology 20000701
Title: Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.
Journal: Cancer research 20000701
Title: Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells.
Journal: Gastroenterology 20000601
Title: Colon cancer chemopreventive drugs modulate integrin-mediated signaling pathways.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20000301
Title: Transcriptional regulation of cyclooxygenase-2 gene expression: novel effects of nonsteroidal anti-inflammatory drugs.
Journal: Cancer research 20000215
Title: Inhibition of rat colon tumors by sulindac and sulindac sulfone is independent of K-ras (codon 12) mutation.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20000201
Title: Treatment and survival study in the C57BL/6J-APC(Min)/+(Min) mouse with R-flurbiprofen.
Journal: Life sciences 20000114
Title: A new concept of tumor promotion by tumor necrosis factor-alpha, and cancer preventive agents (-)-epigallocatechin gallate and green tea--a review.
Journal: Cancer detection and prevention 20000101
Title: PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs.
Journal: Cell 19991029
Title: Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac.
Journal: Gastroenterology 19991001
Title: Sulindac inhibits activation of the NF-kappaB pathway.
Journal: The Journal of biological chemistry 19990917
Title: Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs.
Journal: Cancer research 19990901
Title: Drug-associated cholelithiasis: a case of sulindac stone formation and the incorporation of sulindac metabolites into the gallstones.
Journal: The American journal of gastroenterology 19990801
Title: Green tea and cancer chemoprevention.
Journal: Mutation research 19990716
Title: Chemopreventive efficacy of sulindac sulfone against colon cancer depends on time of administration during carcinogenic process.
Journal: Cancer research 19990715
Title: Nitric oxide prevents anoxia-induced apoptosis in colonic HT29 cells.
Journal: Archives of biochemistry and biophysics 19990615
Title: Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes.
Journal: Cytokine 19990501
Title: Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19990401
Title: Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice.
Journal: Carcinogenesis 19990401
Title: Nonsteroidal anti-inflammatory drugs enhance glutathione S-transferase theta levels in rat colon.
Journal: Biochimica et biophysica acta 19980824
Title: Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction.
Journal: Cancer research 19970615
Title: Renal impairment after acute diclofenac, naproxen, and sulindac overdoses.
Journal: Journal of toxicology. Clinical toxicology 19950101
Title: The influence of sulindac on experimental streptozotocin-induced diabetic neuropathy.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19940801
Title: [Acute immunoallergic hemolytic anemia induced by sulindac].
Journal: La Revue de medecine interne 19940301
Title: Sulindac-induced immune hemolytic anemia.
Journal: Transfusion 19940301
Title: [Development of Stevens-Johnson syndrome following sulindac administration in a patient with mixed connective tissue disease].
Journal: Ryumachi. [Rheumatism] 19931001
Title: Naproxen-induced recurrent aseptic meningitis.
Journal: DICP : the annals of pharmacotherapy 19911101
Title: Effects of sulindac and naproxen on prostaglandin excretion in patients with impaired renal function and rheumatoid arthritis.
Journal: The American journal of medicine 19900901
Title: Aplastic anaemia associated with a non-steroidal anti-inflammatory drug: relapse after exposure to another such drug.
Journal: BMJ (Clinical research ed.) 19900707
Title: Auditory and visual hallucinations associated with sulindac: focus on prostaglandin synthesis and psychotic symptoms.
Journal: Psychosomatics 19900101
Title: Sulindac-induced aseptic meningitis in mixed connective tissue disease.
Journal: Clinical neurology and neurosurgery 19890101
Title: Recurrent sulindac-induced aseptic meningitis in a patient tolerant to other nonsteroidal anti-inflammatory drugs.
Journal: Southern medical journal 19881101
Title: Renal failure and nephrotic syndrome associated with sulindac.
Journal: Clinical nephrology 19880701
Title: Non-steroidal anti-inflammatory nephrotoxicity.
Journal: Annals of clinical and laboratory science 19880101
Title: Reduced incidence of hyperkalemia and azotemia in patients receiving sulindac compared with indomethacin.
Journal: Nephron 19880101
Title: Acute cholangitis and pancreatitis associated with sulindac (clinoril).
Journal: Histopathology 19870601
Title: Hyperkalemia associated with sulindac therapy.
Journal: The Journal of rheumatology 19861201
Title: Encephalopathy associated with sulindac.
Journal: Human toxicology 19860101
Title: Sulindac is not renal sparing in man.
Journal: Clinical pharmacology and therapeutics 19850901
Title: Sulindac hepatotoxicity: effects of acute and chronic exposure.
Journal: Australian and New Zealand journal of medicine 19850801
Title: Immune hemolytic anemia associated with sulindac.
Journal: Archives of internal medicine 19850801
Title: Acute renal effects of sulindac and indomethacin in chronic renal failure.
Journal: Clinical pharmacology and therapeutics 19850401
Title: Increased glomerular thromboxane synthesis as a possible cause of proteinuria in experimental nephrosis.
Journal: The Journal of clinical investigation 19850101
Title: Hypersensitivity reaction to sulindac (Clinoril).
Journal: Archives of internal medicine 19841101
Title: Anaphylactic reaction associated with sulindac.
Journal: Annals of emergency medicine 19840601
Title: Sulindac-induced acute interstitial nephritis.
Journal: The New Zealand medical journal 19840411
Title: Renal papillary necrosis due to naproxen.
Journal: The Journal of rheumatology 19840201
Title: Effect of prostaglandin synthetase inhibitors on experimentally induced convulsions in rats.
Journal: Pharmacology 19840101
Title: Temporary hearing loss induced by combinations of intense sounds and nonsteroidal anti-inflammatory drugs.
Journal: American journal of otolaryngology 19840101
Title: Sulindac-induced meningitis in mixed connective tissue disease.
Journal: Southern medical journal 19830901
Title: Recurrent aseptic meningitis due to sulindac.
Journal: Annals of internal medicine 19830901
Title: Sulindac and renal impairment.
Journal: JAMA 19830603
Title: Peripheral neuropathy after concomitant administration of dimethyl sulfoxide and sulindac.
Journal: Arthritis and rheumatism 19830601
Title: Effect of prostaglandin synthetase inhibitors on non-analgesic actions of morphine.
Journal: European journal of pharmacology 19830520
Title: Sulindac. A potentially renal-sparing nonsteroidal anti-inflammatory drug.
Journal: JAMA 19821203
Title: Peripheral neuropathy after concomitant dimethyl sulfoxide use and sulindac therapy.
Journal: Archives of physical medicine and rehabilitation 19821101
Title: Sulindac hepatotoxicity.
Journal: Gut 19821001
Title: Papillary necrosis mimicking staghorn calculi.
Journal: Urology 19820901
Title: Cholestatic jaundice caused by sulindac.
Journal: Canadian journal of surgery. Journal canadien de chirurgie 19820501
Title: Sulindac-induced aseptic meningitis.
Journal: Archives of internal medicine 19820101
Title: Sulindac (Clinoril) hepatitis.
Journal: Gastroenterology 19810301
Title: Nephrotic syndrome associated with sulindac.
Journal: The New England journal of medicine 19810212
Title: Myasthenia gravis and penicillamine therapy of rheumatoid arthritis.
Journal: JAMA 19801017
Title: Sulindac-induced bone marrow toxicity.
Journal: Lancet (London, England) 19801011
Title: Hypertensive reaction with sulindac.
Journal: Canadian Medical Association journal 19800607
Title: Delirium associated with sulindac.
Journal: JAMA 19800425
Title: Marrow aplasia and sulindac.
Journal: Annals of internal medicine 19800101
Title: [Ionized fluorine in the plasma and urine of subjects treated with organofluorine drugs prescribed in rheumatology].
Journal: Revue du rhumatisme et des maladies osteo-articulaires 19790201