Title: Contributions of arylacetamide deacetylase and carboxylesterase 2 to flutamide hydrolysis in human liver.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120601
Title: Production of human metabolites of the anti-cancer drug flutamide via biotransformation in Cunninghamella species.
Journal: Biotechnology letters 20110201
Title: Microbial metabolism. Part 11. Metabolites of flutamide.
Journal: Chemical & pharmaceutical bulletin 20100401
Title: Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090701
Title: Role of enzymatic N-hydroxylation and reduction in flutamide metabolite-induced liver toxicity.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090101
Title: Bioactivation of flutamide metabolites by human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701
Title: Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites.
Journal: Chemical research in toxicology 20071001
Title: Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601
Title: Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060501
Title: Pharmacokinetics and metabolism of a selective androgen receptor modulator in rats: implication of molecular properties and intensive metabolic profile to investigate ideal pharmacokinetic characteristics of a propanamide in preclinical study.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060301
Title: Flutamide-induced hepatic dysfunction in relation to steady-state plasma concentrations of flutamide and its metabolites.
Journal: Molecular and cellular biochemistry 20031001
Title: Hydrogen bonding in C-substituted nitroanilines: molecular ladders in 2-trifluoromethyl-4-nitroaniline and sheets of R(4)(4)(12) and R(4)(4)(32) rings in 3-trifluoromethyl-4-nitroaniline.
Journal: Acta crystallographica. Section C, Crystal structure communications 20020201
Title: The pharmacokinetics of flutamide and its major metabolites after a single oral dose and during chronic treatment.
Journal: European journal of clinical pharmacology 19880101
