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39492-01-8,MFCD00867386
Catalog No.:AA00I7OV

39492-01-8 | methanesulfonic acid ethyl 4-[(6-carbamimidamidohexanoyl)oxy]benzoate

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250mg
≥ 95 %
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$576.00   $403.00
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≥ 95 %
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  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I7OV
Chemical Name:
methanesulfonic acid ethyl 4-[(6-carbamimidamidohexanoyl)oxy]benzoate
CAS Number:
39492-01-8
Molecular Formula:
C16H23N3O4
Molecular Weight:
321.3715
MDL Number:
MFCD00867386
SMILES:
CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N
Properties
Computed Properties
 
Complexity:
400  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
11  
XLogP3:
1.4  

Literature

Title: Preconditioning with gabexate is superior to inosine for ameliorating acute renal ischemia-reperfusion injury in rats.

Journal: Transplantation proceedings 20140101

Title: Clinical efficacy of gabexate mesilate for acute pancreatitis in children.

Journal: European journal of pediatrics 20131101

Title: Reduced sodium transport with nasal administration of the prostasin inhibitor camostat in subjects with cystic fibrosis.

Journal: Chest 20130701

Title: Effect of a serine protease inhibitor on the progression of chronic renal failure.

Journal: American journal of physiology. Renal physiology 20121015

Title: In vivo contribution of serine proteases to the proteolytic activation of γENaC in aldosterone-infused rats.

Journal: American journal of physiology. Renal physiology 20121001

Title: Nafamostat mesilate, a noncalcium compound, as an anticoagulant, induces calcium-dependent haemolysis when infused with packed erythrocytes.

Journal: Transfusion medicine (Oxford, England) 20120601

Title: An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.

Journal: The Journal of clinical investigation 20120402

Title: [Could nafamostat or gabexate prevent the post endoscopic retrograde cholangiopancreatography pancreatitis?].

Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20120301

Title: Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension.

Journal: Clinical and experimental nephrology 20120201

Title: Duodenal myotomy blocks reduction of meal size and prolongation of intermeal interval by cholecystokinin.

Journal: Physiology & behavior 20120201

Title: Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KRAS, BRAF and PIK3CA mutations.

Journal: PloS one 20120101

Title: Effect of synthetic protease inhibitor gabexate mesilate on attenuation of coagulant activity and cytokine release in a rat model of islet transplantation.

Journal: Transplantation proceedings 20111101

Title: Oral delivery system for two-pulse colonic release of protein drugs and protease inhibitor/absorption enhancer compounds.

Journal: Journal of pharmaceutical sciences 20110801

Title: Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.

Journal: Pain 20110801

Title: The short term satiety peptide cholecystokinin reduces meal size and prolongs intermeal interval.

Journal: Peptides 20110601

Title: Is entirely conservative management a correct strategy for hemodynamically stable patient with a grade IV blunt pancreatic injury?

Journal: World journal of surgery 20110401

Title: ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.

Journal: Innate immunity 20110201

Title: [Synthetic protease inhibitors for the treatment of DIC].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20110201

Title: Gabexate mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury.

Journal: The Journal of surgical research 20110101

Title: The effects of gabexate mesilate on the microsurgical reconstruction of the hepatic artery in living donor liver transplantation.

Journal: Transplantation proceedings 20101201

Title: Effects of a synthetic protease inhibitor (gabexate mesilate) and a neutrophil elastase inhibitor (sivelestat sodium) on acid-induced lung injury in rats.

Journal: European journal of pharmacology 20100901

Title: Regulator of calcineurin 1 controls growth plasticity of adult pancreas.

Journal: Gastroenterology 20100801

Title: Release of interleukin-1 receptor antagonist by combining a leukocyte adsorption carrier with ulinastatin.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20100801

Title: Refractory chronic urticaria treated effectively with the protease inhibitors, nafamostat mesilate and camostat mesilate.

Journal: Acta dermato-venereologica 20100701

Title: Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure.

Journal: Journal of gastroenterology and hepatology 20100701

Title: Tumor-derived trypsin enhances proliferation of intrahepatic cholangiocarcinoma cells by activating protease-activated receptor-2.

Journal: International journal of oncology 20100401

Title: Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease.

Journal: Journal of gastroenterology 20100301

Title: Post-ERCP pancreatitis.

Journal: Journal of hepato-biliary-pancreatic sciences 20100101

Title: [Treatment of disseminated intravascular coagulation].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20100101

Title: Stability of gabexate mesilate products: Influence of the addition of mannitol.

Journal: Bio-medical materials and engineering 20100101

Title: C5a-inhibitory peptide combined with gabexate mesilate prevents the instant blood-mediated inflammatory reaction in a rat model of islet transplantation.

Journal: Transplantation proceedings 20100101

Title: The specific inhibition of HepG2 cells proliferation by apoptosis induced by gabexate mesilate.

Journal: International journal of clinical and experimental pathology 20100101

Title: [Treatment of DIC associated with myelogenous leukemia].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20091001

Title: Continuous regional arterial infusion therapy for acute necrotizing pancreatitis due to Mycoplasma pneumoniae infection in a child.

Journal: Cardiovascular and interventional radiology 20090501

Title: Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease.

Journal: The Journal of pharmacology and experimental therapeutics 20090501

Title: Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations.

Journal: Protein science : a publication of the Protein Society 20090501

Title: Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.

Journal: Journal of hypertension 20090101

Title: C5a inhibitory peptide combined with gabexate mesilate is a clinically available candidate for preventing the instant blood-mediated inflammatory reaction.

Journal: Transplantation proceedings 20090101

Title: Modelling of tumour--host coexistence In vitro in the presence of serine protease inhibitors.

Journal: In vivo (Athens, Greece) 20090101

Title: Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis.

Journal: World journal of gastroenterology 20081107

Title: Choledochoscope manometry about different drugs on the Sphincter of Oddi.

Journal: World journal of gastroenterology 20081014

Title: Activation of submucosal but not myenteric plexus of the gastrointestinal tract accompanies reduction of food intake by camostat.

Journal: Regulatory peptides 20081009

Title: The effects of a new human leukocyte elastase inhibitor (recombinant guamerin) on cerulein-induced pancreatitis in rats.

Journal: International immunopharmacology 20080701

Title: Protective effects of amino acids against gabexate mesilate-induced cell injury in porcine aorta endothelial cells.

Journal: Journal of pharmacological sciences 20080701

Title: Pharmacological approach to acute pancreatitis.

Journal: World journal of gastroenterology 20080521

Title: CCK-induced pancreatic growth is not limited by mitogenic capacity in mice.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080501

Title: Characteristics of gabexate mesilate-induced cell injury in porcine aorta endothelial cells.

Journal: Journal of pharmacological sciences 20080301

Title: Somatostatin bolus injection for post-ERCP pancreatitis prevention: a need for further study.

Journal: Gastrointestinal endoscopy 20080101

Title: Synthetic serine protease inhibitor, gabexate mesilate, prevents nuclear factor-kappaB activation and increases TNF-alpha-mediated apoptosis in human pancreatic cancer cells.

Journal: Digestive diseases and sciences 20071001

Title: Early successes and late failures in the prevention of post endoscopic retrograde cholangiopancreatography.

Journal: World journal of gastroenterology 20070714

Title: Antiproteases in preventing post-ERCP acute pancreatitis.

Journal: JOP : Journal of the pancreas 20070709

Title: Somatostatin and gabexate for post-endoscopic retrograde cholangiopancreatography pancreatitis prevention: meta-analysis of randomized placebo-controlled trials.

Journal: Journal of gastroenterology and hepatology 20070701

Title: Efficacy of postprocedure administration of gabexate mesylate in the prevention of post-ERCP pancreatitis: a randomized, controlled, multicenter study.

Journal: Gastrointestinal endoscopy 20070601

Title: The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents.

Journal: Life sciences 20070501

Title: Translocation of pancreatic juice after ischemia and reperfusion of the intestines and the effects of gabexate mesilate (FOY) in rats.

Journal: Transplantation proceedings 20070501

Title: Prophylactic administration of somatostatin or gabexate does not prevent pancreatitis after ERCP: an updated meta-analysis.

Journal: Gastrointestinal endoscopy 20070401

Title: Risk for post-ERCP pancreatitis after needle knife precut sphincterotomy following repeated cannulation attempts.

Journal: Journal of clinical gastroenterology 20070401

Title: Pancreatic diabetes in a follow-up survey of chronic pancreatitis in Japan.

Journal: Journal of gastroenterology 20070401

Title: Prophylaxis of post-ERCP pancreatic complications with gabexate.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20070301

Title: [Typhoid fever and acute pancreatitis: two cases].

Journal: Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20070301

Title: Induction of early response genes in trypsin inhibitor-induced pancreatic growth.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070201

Title: Evaluation of serum amylase and gabexate mesilate with endoscopic papillary balloon dilatation.

Journal: The journal of medical investigation : JMI 20070201

Title: Gabexate in the prophylaxis of post-ERCP pancreatitis: a meta-analysis of randomized controlled trials.

Journal: BMC gastroenterology 20070101

Title: The papilla of Vater just below the pylorus presenting as recurrent duodenal ulcer bleeding.

Journal: Internal medicine (Tokyo, Japan) 20070101

Title: Successful intermittent application of the Pringle maneuver for 30 minutes during human hepatectomy: a clinical randomized study with use of a protease inhibitor.

Journal: Hepato-gastroenterology 20070101

Title: Successful liver transplantation across the ABO incompatibility barrier in 6 cases of biliary atresia.

Journal: Journal of pediatric surgery 20061201

Title: A case of feline pancreatitis.

Journal: The Journal of veterinary medical science 20061201

Title: Boerhaave syndrome treated conservatively following early endoscopic diagnosis: a case report.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20061201

Title: Frequency of post-ERCP pancreatitis in a single tertiary referral centre without and with routine prophylaxis with gabexate: a 6-year survey and cost-effectiveness analysis.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20060801

Title: Pharmacological prevention of post-ERCP pancreatitis--an everlasting dream?

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20060801

Title: Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma.

Journal: The Journal of allergy and clinical immunology 20060701

Title: [Effects of Chinese herbal medicines on spontaneous chronic pancreatitis in rats and the pathological relationships between formulas and syndromes].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060701

Title: Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice.

Journal: The Journal of physiology 20060615

Title: Properties of poly(lactic-co-glycolic acid) nanospheres containing protease inhibitors: camostat mesilate and nafamostat mesilate.

Journal: International journal of pharmaceutics 20060511

Title: Effects of gabexate mesilate on ischemia-reperfusion-induced testicular injury in rats.

Journal: Pediatric surgery international 20060501

Title: Calcineurin-dependent and calcineurin-independent signal transduction pathways activated as part of pancreatic growth.

Journal: Pancreas 20060401

Title: Efficacy of camostat mesilate compared with famotidine for treatment of functional dyspepsia: is camostat mesilate effective?

Journal: Journal of gastroenterology and hepatology 20060401

Title: Evidence-based treatment of acute pancreatitis: a look at established paradigms.

Journal: Annals of surgery 20060201

Title: Effects of gabexate mesilate on serum inflammatory cytokines in rats with acute necrotizing pancreatitis.

Journal: Cytokine 20060121

Title: New approaches for the treatment of acute pancreatitis.

Journal: JOP : Journal of the pancreas 20060111

Title: Evaluation of a protease inhibitor in the prevention of ischemia and reperfusion injury in hepatectomy under intermittent Pringle maneuver.

Journal: American journal of surgery 20060101

Title: Clinical trial of gabexate in the prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060101

Title: A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis.

Journal: Modern rheumatology 20060101

Title: Beneficial effect of gabexate mesilate on microscopic polyangiitis with renal dysfunction and pulmonary hemorrhage: A case report.

Journal: Angiology 20060101

Title: Pharmacological management of pancreatitis.

Journal: Current opinion in pharmacology 20051201

Title: Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats.

Journal: Journal of gastroenterology and hepatology 20050601

Title: Water and enzyme secretion are tightly coupled in pancreatic secretion stimulated by food or CCK-58 but not by CCK-8.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050501

Title: Synthetic protease inhibitor camostat prevents and reverses dyslipidemia, insulin secretory defects, and histological abnormalities of the pancreas in genetically obese and diabetic rats.

Journal: Metabolism: clinical and experimental 20050501

Title: Effects of gabexate mesilate (FOY) on amylase and phospholipase A2 in human serum and pancreatic juice.

Journal: Digestive diseases and sciences 20050501

Title: Gabexate mesilate and acute pancreatitis: an experience of evidence based drug information for improving rational drug use.

Journal: Pharmacy world & science : PWS 20050401

Title: Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats.

Journal: Journal of gastroenterology 20050301

Title: Effect of synthetic protease inhibitor gabexate mesilate on the attenuation of ischemia/reperfusion injury in canine kidney autotransplantation.

Journal: Surgery 20050201

Title: Preventive and therapeutic effects of the protease inhibitor camostat on pancreatic fibrosis and atrophy in CCK-1 receptor-deficient rats.

Journal: Pancreas 20050101

Title: Antimetastatic activity of a synthetic serine protease inhibitor, FOY-305 (Foypan).

Journal: In vivo (Athens, Greece) 20050101

Title: Gabexate mesilate hastens recovery from vecuronium-induced neuromuscular blockade.

Journal: European journal of anaesthesiology 20050101

Title: Use of low dose dopamine, gabexate mesilate and ulinastatin reduces the water balance and pulmonary complication in thoracic esophagectomy patients.

Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20050101

Title: [Hepatic portal venous gas--a report of two cases successfully treated with conservative management].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20041210

Title: [Essential therapeutic strategies for acute pancreatitis--guidelines for initial treatment and their significance].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20041101

Title: [Treatment of acute pancreatitis with protease inhibitor, H2 receptor antagonist and somatostatin analogue].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20041101

Title: Treatment of acute pancreatitis with protease inhibitors: a meta-analysis.

Journal: European journal of gastroenterology & hepatology 20041101

Title: The effect of continuous arterial infusion of gabexate mesilate (FOY-007) on experimental acute pancreatitis.

Journal: The journal of medical investigation : JMI 20040801

Title: Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040701

Title: Tumor protein p53-induced nuclear protein 1 (TP53INP1) in spontaneous chronic pancreatitis in the WBN/Kob rat: drug effects on its expression in the pancreas.

Journal: JOP : Journal of the pancreas 20040701

Title: Calcineurin mediates pancreatic growth in protease inhibitor-treated mice.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20040501

Title: [Changes in coagulation, fibrinolysis and platelet functions during extracorporeal circulation].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040501

Title: Gabexate mesilate and heparin responsiveness in coronary patients.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20040301

Title: [Autoimmune pancreatitis].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040110

Title: Preparation and characterization of starch/cyclodextrin bioadhesive microspheres as platform for nasal administration of Gabexate Mesylate (Foy) in allergic rhinitis treatment.

Journal: Biomaterials 20040101

Title: Circulating ethanol does not stimulate pancreatic secretion in conscious rats.

Journal: Pancreas 20031101

Title: [A case of severe Chlamydia pneumoniae pneumonia requiring mechanical ventilation and complicated with disseminated intravascular coagulation].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20031101

Title: CCK-58 is the only detectable endocrine form of cholecystokinin in rat.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030801

Title: Involvement of proteinase-activated receptor-2 in mast cell tryptase-induced barrier dysfunction in bovine aortic endothelial cells.

Journal: Cellular signalling 20030801

Title: Nafamostat mesilate is an extremely potent inhibitor of human tryptase.

Journal: Journal of pharmacological sciences 20030801

Title: [Prevention of hemorrhage occurring in patients with leukemia].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20030610

Title: Use of gabexate mesylate in Italian hospitals: a multicentre observational study.

Journal: Journal of clinical pharmacy and therapeutics 20030601

Title: Effects of bioactive agents on biliary motor function.

Journal: Current gastroenterology reports 20030401

Title: Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappaB and activator protein-1 in human monocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20030401

Title: Gabexate mesilate, a synthetic anticoagulant, inhibits the expression of endothelial leukocyte adhesion molecules in vitro.

Journal: Critical care medicine 20030401

Title: Systematic skepticism.

Journal: Critical care medicine 20030401

Title: Changes in blood viscosity with synthetic protease inhibitors.

Journal: Journal of pharmacological sciences 20030401

Title: Morphological relationship between intercalated duct and pancreatic islet in streptozotocin and/or camostat mesilate administrations in the chicken.

Journal: Anatomia, histologia, embryologia 20030401

Title: Results of treating severe acute pancreatitis with gabexate is associated with neutrophil apoptosis activity.

Journal: Hepato-gastroenterology 20030101

Title: Does gabexate mesilate affect serum concentrations of acute phase proteins after endoscopic retrograde cholangiopancreatography examination?

Journal: Hepato-gastroenterology 20030101

Title: Acute pancreatitis occurring in the early postpartum period: a case report.

Journal: Journal of perinatal medicine 20030101

Title: Gabexate mesilate (FOY) inhibition of amylase and phospholipase A(2) activity in sow pancreatic juice.

Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20030101

Title: A possible defensive mechanism in the basal region of gastric mucosa and the healing of erosions.

Journal: Clinical hemorheology and microcirculation 20030101

Title: Gabexate mesilate and/or octreotide in human immunodeficiency virus-associated pancreatic abnormalities.

Journal: Alimentary pharmacology & therapeutics 20021001

Title: Gabexate or somatostatin administration before ERCP in patients at high risk for post-ERCP pancreatitis: a multicenter, placebo-controlled, randomized clinical trial.

Journal: Gastrointestinal endoscopy 20021001

Title: Biological phenotype determination with ex vivo model in gastric cancer for matrix-metalloproteinase inhibitor treatment.

Journal: International journal of molecular medicine 20020901

Title: Early capillary no-reflow during low-flow reperfusion after hind limb ischemia in the rat.

Journal: Annals of plastic surgery 20020801

Title: Modulation of L-arginine transport and nitric oxide production by gabexate mesylate.

Journal: Biochemical pharmacology 20020715

Title: Hepatocyte protection by a protease inhibitor against ischemia/reperfusion injury of human liver.

Journal: Journal of the American College of Surgeons 20020701

Title: Different effects of oral administration of synthetic trypsin inhibitor on the pancreas between cholecystokinin-A receptor gene knockout mice and wild type mice.

Journal: Japanese journal of pharmacology 20020701

Title: Predicting and preventing post-ERCP pancreatitis.

Journal: Current gastroenterology reports 20020401

Title: Effects of gabexate mesilate, a protease inhibitor, on human sphincter of Oddi motility.

Journal: Digestive diseases and sciences 20020401

Title: Novel trial for the treatment of steroid dependency in minimal change disease: combined therapy of camostat mesilate and glycyrrhizin.

Journal: Nephron 20020301

Title: Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock.

Journal: Shock (Augusta, Ga.) 20020301

Title: [Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20020301

Title: Differential cytokine response in host defence mechanisms triggered by gram-negative and gram-positive bacteria, and the roles of gabexate mesilate, a synthetic protease inhibitor.

Journal: The Journal of international medical research 20020101

Title: A case of primary Sjögren's syndrome associated with low titer cold agglutinin disease.

Journal: Clinical and experimental rheumatology 20020101

Title: Inhibition of natural killer cytotoxicity in vitro by clinical grade serine protease inhibitors.

Journal: Haematologia 20020101

Title: Fatal cases of gabexate mesilate-induced anaphylaxis.

Journal: International journal of clinical pharmacology research 20020101

Title: Combinatorial synthesis of SSAO inhibitors using sonogashira coupling: SAR of aryl propargylic amines.

Journal: Bioorganic & medicinal chemistry letters 20011008

Title: Granulomatous tubulointerstitial nephritis induced by all-trans retinoic acid.

Journal: Anti-cancer drugs 20010901

Title: Regional effects of nafamostat, a novel potent protease and complement inhibitor, on severe necrotizing pancreatitis.

Journal: Surgery 20010801

Title: Successful treatment of DIC with a serine proteinase inhibitor.

Journal: The American journal of emergency medicine 20010701

Title: Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta.

Journal: Gastroenterology 20010601

Title: Effects of synthetic serine protease inhibitors on proliferation and collagen synthesis of human pancreatic periacinar fibroblast-like cells.

Journal: Pancreas 20010401

Title: Selective inhibition of human mast cell tryptase by gabexate mesylate, an antiproteinase drug.

Journal: Biochemical pharmacology 20010201

Title: Preparation and characterization of biodegradable or enteric-coated microspheres containing the protease inhibitor camostat.

Journal: The Journal of pharmacy and pharmacology 20010201

Title: [Can post-ERCP acute pancreatitis be predicted and prevented?].

Journal: Gastroenterologie clinique et biologique 20010101

Title: [Gabexate mesilate vs gabexate mesilate combined with octreotide in the prevention of postoperative complications of pancreatic surgery: preliminary results].

Journal: Chirurgia italiana 20010101

Title: Gabexate mesilate in acute pancreatitis: miracle or mirage?

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20010101

Title: Multicentre comparative study of two schedules of gabexate mesilate in the treatment of acute pancreatitis. Italian Acute Pancreatitis Study Group.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20010101

Title: Inhibition of pig liver and Zea mays L. polyamine oxidase: a comparative study.

Journal: Journal of enzyme inhibition 20010101

Title: Continuous regional arterial infusion (CRAI) therapy reduces the mortality rate of acute necrotizing pancreatitis: results of a cooperative survey in Japan.

Journal: Journal of hepato-biliary-pancreatic surgery 20010101

Title: Gabexate mesilate in acute pancreatitis: neither a miracle nor a mirage, merely the search of optimal dosage.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20010101

Title: Acceleration of ulcer healing by cholecystokinin (CCK): role of CCK-A receptors, somatostatin, nitric oxide and sensory nerves.

Journal: Regulatory peptides 19990630

Title: Gabexate mesylate inhibition of serine proteases: thermodynamic and computer-graphics analysis.

Journal: Journal of pharmaceutical sciences 19861201

Title: Synthetic inhibitors of trypsin, plasmin, kallikrein, thrombin, C1r-, and C1 esterase.

Journal: Biochimica et biophysica acta 19771013

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Tags:39492-01-8 Molecular Formula|39492-01-8 MDL|39492-01-8 SMILES|39492-01-8 methanesulfonic acid ethyl 4-[(6-carbamimidamidohexanoyl)oxy]benzoate