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39552-01-7,MFCD00864594
Catalog No.:AA00C96P

39552-01-7 | Befunolol

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25mg
3 weeks  
$530.00   $371.00
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250mg
3 weeks  
$2,786.00   $1,950.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C96P
Chemical Name:
Befunolol
CAS Number:
39552-01-7
Molecular Formula:
C16H21NO4
Molecular Weight:
291.3422
MDL Number:
MFCD00864594
SMILES:
OC(COc1cccc2c1oc(c2)C(=O)C)CNC(C)C
Properties
Computed Properties
 
Complexity:
347  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2  

Literature

Title: Short-term effect of topical antiglaucoma medication on tear-film stability, tear secretion, and corneal sensitivity in healthy subjects.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20110101

Title: Sick sinus syndrome associated with topical timolol maleate instillation.

Journal: Journal of pharmacology & pharmacotherapeutics 20110101

Title: Reconstruction of a human cornea by the self-assembly approach of tissue engineering using the three native cell types.

Journal: Molecular vision 20100101

Title: Pharmacological evaluation of ocular beta-adrenoceptors in rabbit by tissue segment binding method.

Journal: Life sciences 20090130

Title: Allergic contact dermatitis due to levobunolol with cross-sensitivity to befunolol.

Journal: Contact dermatitis 20070101

Title: Utilization of 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) for kinetic spectrophotometric assay of befunolol hydrochloride in its pharmaceutical formulation.

Journal: Journal of AOAC International 20060101

Title: Human cornea construct HCC-an alternative for in vitro permeation studies? A comparison with human donor corneas.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050701

Title: Human corneal equivalent as cell culture model for in vitro drug permeation studies.

Journal: The British journal of ophthalmology 20040401

Title: [Levels of antiphospholipid antibodies in the serum and aqueous humor of glaucoma patients].

Journal: Klinika oczna 20040101

Title: The use of a porcine organotypic cornea construct for permeation studies from formulations containing befunolol hydrochloride.

Journal: International journal of pharmaceutics 20030102

Title: Contact dermatitis to topical drugs for glaucoma.

Journal: American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20011201

Title: Allergic contact dermatitis due to the beta-blocker befunolol in eyedrops, with cross-sensitivity to carteolol.

Journal: Contact dermatitis 20010601

Title: Assessment of systemic adverse reactions induced by ophthalmic beta-adrenergic receptor antagonists.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601

Title: Aqueous humor dynamics in beagle dogs with caffeine-induced ocular hypertension.

Journal: The Journal of veterinary medical science 19980601

Title: Relationship between caffeine-induced ocular hypertension and ultrastructure changes of non-pigmented ciliary epithelial cells in rats.

Journal: The Journal of toxicological sciences 19971201

Title: Takayanagi I, et al. A beta-adrenoceptor blocking agent, befunolol as a partial agonist in isolated organs. Gen Pharmacol. 1985;16(3):265-7.

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